# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Aa_trans PF01490.18 EST41294.1 - 1.6e-07 30.4 5.9 1.7e-07 30.3 5.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AAA PF00004.29 EST41295.1 - 1.5e-09 38.3 0.0 2.5e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EST41295.1 - 0.0017 18.5 0.0 0.0027 17.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EST41295.1 - 0.017 15.1 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EST41295.1 - 0.038 14.4 0.0 0.065 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EST41295.1 - 0.11 12.9 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 EST41296.1 - 3.3e-23 82.6 0.0 3.7e-23 82.4 0.0 1.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SBBP PF06739.11 EST41296.1 - 0.0054 16.7 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Beta-propeller repeat AAA PF00004.29 EST41297.1 - 0.00048 20.5 0.1 0.0011 19.4 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EST41297.1 - 0.018 14.4 0.0 0.043 13.2 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EST41297.1 - 0.03 14.3 0.1 0.08 12.9 0.1 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EST41297.1 - 0.046 14.0 0.0 0.095 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EST41297.1 - 0.096 13.1 0.0 0.22 11.9 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.17 EST41297.1 - 0.16 11.7 0.0 0.42 10.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Spc7 PF08317.11 EST41298.1 - 0.11 11.4 12.5 0.011 14.7 4.6 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Vir_act_alpha_C PF10400.9 EST41298.1 - 0.45 11.2 3.9 0.63 10.8 0.1 2.5 2 0 0 2 2 2 0 Virulence activator alpha C-term Laminin_II PF06009.12 EST41298.1 - 0.64 10.0 7.5 3.5 7.7 1.4 2.3 2 0 0 2 2 2 0 Laminin Domain II YabA PF06156.13 EST41298.1 - 2.9 8.6 7.8 1.7 9.3 3.7 2.3 2 0 0 2 2 2 0 Initiation control protein YabA Fmp27_WPPW PF10359.9 EST41298.1 - 3.4 6.4 15.0 0.34 9.7 6.1 2.1 1 1 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain NPV_P10 PF05531.12 EST41298.1 - 4.1 7.9 10.5 0.35 11.4 2.3 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 EST41298.1 - 6 7.0 14.5 0.63 10.2 5.1 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family GIT_CC PF16559.5 EST41298.1 - 7.8 6.5 11.6 1.4 8.8 5.2 2.5 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor CENP-H PF05837.12 EST41298.1 - 8.9 6.8 9.0 8.7 6.8 2.3 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) ZapB PF06005.12 EST41300.1 - 0.013 15.9 6.0 2.6 8.6 3.1 2.9 2 0 0 2 2 2 0 Cell division protein ZapB NRBF2 PF08961.10 EST41300.1 - 0.12 12.0 2.1 0.42 10.2 0.3 2.2 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator TSC22 PF01166.18 EST41300.1 - 0.16 12.3 9.9 0.42 10.9 1.2 3.5 4 0 0 4 4 4 0 TSC-22/dip/bun family YabA PF06156.13 EST41300.1 - 0.26 12.0 11.8 0.12 13.0 1.3 3.4 3 1 1 4 4 4 0 Initiation control protein YabA Shugoshin_N PF07558.11 EST41300.1 - 0.45 10.4 6.8 12 5.8 0.5 3.3 2 1 0 2 2 2 0 Shugoshin N-terminal coiled-coil region bZIP_1 PF00170.21 EST41300.1 - 0.49 10.5 6.2 15 5.8 2.5 2.9 2 0 0 2 2 2 0 bZIP transcription factor CENP-H PF05837.12 EST41300.1 - 0.51 10.8 5.7 3.4 8.1 0.9 2.7 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF2553 PF10830.8 EST41301.1 - 0.068 14.0 0.6 0.096 13.5 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2553) TAFII28 PF04719.14 EST41301.1 - 0.34 11.0 3.1 0.34 11.0 0.7 2.0 2 0 0 2 2 2 0 hTAFII28-like protein conserved region Poxvirus_B22R_N PF13169.6 EST41302.1 - 0.03 14.8 0.2 0.044 14.3 0.2 1.2 1 0 0 1 1 1 0 Poxvirus B22R protein N-terminal Pkinase PF00069.25 EST41304.1 - 1.6e-70 237.5 0.0 2.2e-70 237.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST41304.1 - 1.9e-34 119.1 0.0 2.6e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EST41304.1 - 9e-06 25.2 0.0 3.1e-05 23.5 0.0 1.8 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 EST41304.1 - 0.0016 18.1 0.0 1.1 8.8 0.0 2.5 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EST41304.1 - 0.0094 15.3 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EST41304.1 - 0.029 13.4 0.0 0.055 12.5 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 EST41304.1 - 0.03 13.3 0.0 0.05 12.5 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EST41304.1 - 0.18 11.7 0.0 0.66 9.9 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family GLTP PF08718.11 EST41305.1 - 4.8e-14 52.9 0.6 1.3e-12 48.3 0.6 2.0 1 1 0 1 1 1 1 Glycolipid transfer protein (GLTP) SPT16 PF08644.11 EST41306.1 - 1.8e-08 34.7 0.2 1.8e-08 34.7 0.2 2.8 3 1 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) SRP54_N PF02881.19 EST41306.1 - 0.12 12.6 1.0 1.6 9.0 0.0 3.2 3 0 0 3 3 3 0 SRP54-type protein, helical bundle domain DUF1283 PF06932.11 EST41306.1 - 0.77 10.0 6.1 0.059 13.6 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1283) TBCA PF02970.16 EST41306.1 - 2.1 8.7 7.0 0.27 11.6 1.1 2.6 2 0 0 2 2 2 0 Tubulin binding cofactor A Matrilin_ccoil PF10393.9 EST41307.1 - 0.099 12.5 0.9 9.8 6.1 0.1 2.3 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin tRNA-synt_2 PF00152.20 EST41308.1 - 2.7e-91 305.9 0.0 3.4e-91 305.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EST41308.1 - 1.7e-11 43.9 0.1 4.5e-11 42.6 0.1 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Raf1_HTH PF18579.1 EST41309.1 - 0.078 12.7 0.8 0.1 12.3 0.3 1.4 2 0 0 2 2 2 0 Rubisco accumulation factor 1 helix turn helix domain PQ-loop PF04193.14 EST41311.1 - 1.1e-21 76.3 20.0 1.6e-12 47.0 4.3 2.9 3 0 0 3 3 3 2 PQ loop repeat Lip_prot_lig_C PF10437.9 EST41312.1 - 0.02 14.9 0.3 0.031 14.3 0.3 1.3 1 0 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus Pox_A_type_inc PF04508.12 EST41312.1 - 0.081 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DUF724 PF05266.14 EST41312.1 - 0.32 10.8 5.9 0.44 10.3 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) FlxA PF14282.6 EST41313.1 - 0.0074 16.3 7.1 0.012 15.6 7.1 1.3 1 0 0 1 1 1 1 FlxA-like protein DNA_pol_A_exo1 PF01612.20 EST41313.1 - 0.014 15.1 0.1 2.6 7.7 0.0 2.1 1 1 1 2 2 2 0 3'-5' exonuclease Sugarporin_N PF11471.8 EST41313.1 - 1.4 9.0 7.3 0.1 12.6 2.4 1.7 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Laminin_EGF PF00053.24 EST41314.1 - 6.8e-09 35.7 51.1 0.0063 16.6 13.7 3.5 1 1 2 3 3 3 3 Laminin EGF domain EGF PF00008.27 EST41314.1 - 0.00019 21.7 34.8 0.016 15.5 3.2 4.2 4 0 0 4 4 4 3 EGF-like domain EGF_2 PF07974.13 EST41314.1 - 4.3 7.8 50.0 0.2 12.0 8.3 4.9 4 0 0 4 4 4 0 EGF-like domain AAA_18 PF13238.6 EST41315.1 - 2.5e-10 41.0 0.0 5.3e-10 40.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EST41315.1 - 4.3e-05 23.8 0.1 9.1e-05 22.8 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EST41315.1 - 0.002 18.3 0.0 0.0055 16.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EST41315.1 - 0.0039 17.5 0.2 0.015 15.6 0.2 2.0 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 EST41315.1 - 0.022 14.6 3.8 0.055 13.3 3.8 1.8 1 1 0 1 1 1 0 Deoxynucleoside kinase AAA_14 PF13173.6 EST41315.1 - 0.026 14.5 0.0 0.064 13.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EST41315.1 - 0.055 13.9 2.0 0.43 11.0 0.1 2.6 2 1 0 2 2 2 0 RNA helicase zf-C3HC4_3 PF13920.6 EST41317.1 - 7.3e-05 22.5 6.2 0.00013 21.7 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EST41317.1 - 8.1e-05 22.5 10.1 0.00016 21.5 10.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EST41317.1 - 0.00035 20.5 4.8 0.00078 19.4 4.8 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EST41317.1 - 0.0013 18.8 9.0 0.0027 17.8 9.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C2H2_3 PF13878.6 EST41317.1 - 0.0037 17.1 3.3 0.91 9.4 0.3 2.7 2 0 0 2 2 2 2 zinc-finger of acetyl-transferase ESCO zf-RING_2 PF13639.6 EST41317.1 - 0.0039 17.5 9.9 0.009 16.3 9.9 1.6 1 1 0 1 1 1 1 Ring finger domain DUF244 PF03112.14 EST41317.1 - 0.0042 16.9 1.0 0.014 15.3 0.6 2.2 2 1 0 2 2 2 1 Uncharacterized protein family (ORF7) DUF zf-C3HC4_2 PF13923.6 EST41317.1 - 0.0046 16.8 4.3 0.0046 16.8 4.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Arena_ncap_C PF17290.2 EST41317.1 - 0.0068 15.8 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Arenavirus nucleocapsid C-terminal domain zf-RING_10 PF16685.5 EST41317.1 - 0.0089 16.1 7.9 0.021 15.0 7.9 1.6 1 1 0 1 1 1 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 EST41317.1 - 0.019 14.8 7.7 0.054 13.4 7.6 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EST41317.1 - 0.028 14.3 10.3 0.053 13.4 10.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EST41317.1 - 0.085 12.6 0.3 0.085 12.6 0.3 3.0 3 0 0 3 3 3 0 RING-like zinc finger zinc_ribbon_13 PF09855.9 EST41317.1 - 4.5 7.5 7.5 1 9.6 0.2 3.1 3 0 0 3 3 3 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) FYVE PF01363.21 EST41317.1 - 4.5 7.5 7.3 18 5.6 7.3 1.9 1 1 0 1 1 1 0 FYVE zinc finger Lip_prot_lig_C PF10437.9 EST41319.1 - 0.02 14.9 0.3 0.031 14.3 0.3 1.3 1 0 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus Pox_A_type_inc PF04508.12 EST41319.1 - 0.081 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DUF724 PF05266.14 EST41319.1 - 0.32 10.8 5.9 0.44 10.3 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) WD40 PF00400.32 EST41320.1 - 1.8e-15 57.1 6.9 0.00032 21.4 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EST41320.1 - 6.1e-15 55.3 0.0 7.4e-06 26.2 0.1 5.1 2 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EST41320.1 - 2.4e-05 24.3 0.1 0.016 15.1 0.0 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cep57_CLD_2 PF14197.6 EST41320.1 - 5.4 7.2 8.9 0.25 11.4 0.6 2.8 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 Xol-1_N PF09108.10 EST41322.1 - 0.016 15.1 0.7 0.028 14.3 0.7 1.4 1 1 0 1 1 1 0 Switch protein XOL-1, N-terminal Aminotran_1_2 PF00155.21 EST41323.1 - 4.5e-37 128.1 0.0 6.3e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EST41323.1 - 0.014 14.7 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EST41323.1 - 0.025 13.9 0.2 0.053 12.8 0.1 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase ABC_tran PF00005.27 EST41324.1 - 2.5e-49 167.3 0.0 1.4e-25 90.4 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EST41324.1 - 3.4e-46 158.1 50.3 5.6e-26 91.8 13.4 2.6 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 EST41324.1 - 1.3e-13 50.9 9.1 4.3e-08 32.9 0.1 4.6 4 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EST41324.1 - 2.3e-05 24.4 0.0 0.31 11.1 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EST41324.1 - 3e-05 24.0 0.7 0.24 11.3 0.1 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EST41324.1 - 4.8e-05 23.0 0.0 0.49 10.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EST41324.1 - 5e-05 23.3 0.0 0.58 9.9 0.0 3.7 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EST41324.1 - 0.00027 21.2 0.0 1.4 9.2 0.0 3.0 2 1 0 2 2 2 2 AAA domain DUF87 PF01935.17 EST41324.1 - 0.0012 19.0 4.7 0.011 15.9 0.1 3.2 3 1 0 3 3 2 1 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 EST41324.1 - 0.0017 17.8 0.0 1.5 8.1 0.0 2.7 2 0 0 2 2 2 2 FtsK/SpoIIIE family Dynamin_N PF00350.23 EST41324.1 - 0.0022 18.1 0.0 0.23 11.5 0.0 3.1 2 0 0 2 2 2 1 Dynamin family AAA_7 PF12775.7 EST41324.1 - 0.0026 17.3 0.0 0.78 9.2 0.0 2.8 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_16 PF13191.6 EST41324.1 - 0.005 17.3 0.0 2.4 8.5 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 EST41324.1 - 0.005 17.4 0.2 0.027 15.0 0.1 4.4 5 1 0 5 5 4 2 AAA domain AAA_18 PF13238.6 EST41324.1 - 0.0051 17.4 0.1 0.97 10.0 0.0 3.5 4 0 0 4 4 2 1 AAA domain IstB_IS21 PF01695.17 EST41324.1 - 0.0085 15.8 0.1 0.36 10.6 0.0 2.9 3 0 0 3 3 3 1 IstB-like ATP binding protein MeaB PF03308.16 EST41324.1 - 0.02 13.9 0.0 0.18 10.8 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 EST41324.1 - 0.02 14.5 0.3 0.82 9.2 0.0 2.8 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain DEAD PF00270.29 EST41324.1 - 0.028 14.2 0.0 47 3.7 0.4 4.3 3 2 0 3 3 3 0 DEAD/DEAH box helicase NACHT PF05729.12 EST41324.1 - 0.043 13.7 0.1 3.1 7.7 0.0 2.9 3 0 0 3 3 2 0 NACHT domain Sigma54_activat PF00158.26 EST41324.1 - 0.076 12.7 0.0 0.27 10.9 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain PRK PF00485.18 EST41324.1 - 0.082 12.6 0.0 8.1 6.1 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ResIII PF04851.15 EST41324.1 - 0.39 10.7 3.9 0.53 10.3 0.0 3.0 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Pkinase PF00069.25 EST41325.1 - 2.2e-65 220.6 0.4 2.2e-65 220.6 0.4 2.1 2 1 1 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST41325.1 - 2.3e-43 148.3 0.3 6.9e-43 146.8 0.3 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EST41325.1 - 0.029 14.3 0.1 0.79 9.6 0.1 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family HAD_2 PF13419.6 EST41327.1 - 3e-28 99.1 0.1 3.9e-28 98.7 0.1 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EST41327.1 - 4.1e-14 53.4 0.0 9.7e-12 45.6 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EST41327.1 - 5e-07 30.3 0.0 9.5e-07 29.4 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EST41327.1 - 0.00015 21.8 0.0 0.00027 20.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like NT5C PF06941.12 EST41327.1 - 0.015 15.2 0.1 0.03 14.2 0.1 1.5 1 1 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Hydrolase_6 PF13344.6 EST41327.1 - 0.11 12.7 0.5 0.54 10.4 0.5 2.2 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase SNF2_N PF00176.23 EST41328.1 - 1.5e-27 96.2 4.0 2.2e-27 95.7 4.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EST41328.1 - 2.5e-13 50.3 2.7 3.6e-13 49.8 0.1 2.5 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EST41328.1 - 4.9e-08 33.2 0.5 4.9e-08 33.2 0.5 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EST41328.1 - 7.8e-06 25.8 0.7 2e-05 24.4 0.7 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 EST41328.1 - 4.6e-05 22.8 0.4 0.0001 21.6 0.4 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_11 PF13086.6 EST41328.1 - 0.084 12.6 0.7 0.22 11.3 0.1 2.0 1 1 1 2 2 2 0 AAA domain GbpA_2 PF18416.1 EST41328.1 - 0.12 12.7 0.7 0.31 11.3 0.5 1.8 2 0 0 2 2 2 0 N-acetylglucosamine binding protein domain 2 PI3K_P85_iSH2 PF16454.5 EST41328.1 - 0.22 11.1 3.6 0.61 9.7 1.6 2.2 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain AFP_2 PF18815.1 EST41328.1 - 6.1 7.2 5.8 18 5.7 0.0 3.3 4 0 0 4 4 4 0 Bacterial antifreeze protein repeat Spectrin_like PF18373.1 EST41329.1 - 0.04 14.0 1.7 0.99 9.5 0.1 2.2 1 1 1 2 2 2 0 Spectrin like domain DUF4407 PF14362.6 EST41330.1 - 0.023 14.0 0.3 0.039 13.3 0.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3782 PF12644.7 EST41330.1 - 0.038 14.1 0.6 0.9 9.7 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3782) DivIC PF04977.15 EST41330.1 - 0.81 9.5 7.5 2.1 8.1 0.1 2.6 3 0 0 3 3 3 0 Septum formation initiator Csm1_N PF18504.1 EST41330.1 - 2 8.8 6.0 3.5 8.0 0.1 2.6 3 0 0 3 3 3 0 Csm1 N-terminal domain ADIP PF11559.8 EST41330.1 - 2.2 8.4 6.3 24 5.0 0.2 2.9 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding SlyX PF04102.12 EST41330.1 - 2.4 8.9 13.5 0.96 10.1 1.6 3.1 2 1 1 3 3 3 0 SlyX bZIP_2 PF07716.15 EST41330.1 - 2.9 8.1 8.8 6 7.0 0.1 2.9 3 0 0 3 3 3 0 Basic region leucine zipper Fer4_20 PF14691.6 EST41331.1 - 1.4e-38 131.1 3.1 2.7e-38 130.2 3.1 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.14 EST41331.1 - 1.2e-35 123.1 2.9 2.1e-35 122.4 2.9 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DHODB_Fe-S_bind PF10418.9 EST41331.1 - 2e-12 46.7 3.3 5.8e-12 45.2 3.3 1.9 1 0 0 1 1 1 1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Pyr_redox PF00070.27 EST41331.1 - 2.6e-12 47.1 5.3 2.5e-08 34.4 0.2 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EST41331.1 - 8e-12 45.0 1.5 5.6e-07 29.1 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EST41331.1 - 1.5e-07 31.0 6.0 9.3e-06 25.1 0.1 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 EST41331.1 - 2.3e-07 31.0 3.5 6.7e-06 26.3 0.5 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EST41331.1 - 5.6e-07 29.3 11.4 9.5e-07 28.5 0.7 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 EST41331.1 - 1e-06 28.2 0.1 0.0063 15.9 0.0 2.5 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 EST41331.1 - 1e-05 24.4 8.0 0.00015 20.7 2.3 2.8 3 0 0 3 3 3 2 HI0933-like protein NAD_binding_1 PF00175.21 EST41331.1 - 1.1e-05 26.0 0.0 3.8e-05 24.3 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_7 PF13241.6 EST41331.1 - 1.9e-05 25.1 2.5 0.025 15.0 0.1 3.0 3 0 0 3 3 2 2 Putative NAD(P)-binding Thi4 PF01946.17 EST41331.1 - 4.7e-05 22.7 0.8 0.0037 16.5 0.3 2.7 2 0 0 2 2 2 1 Thi4 family AdoHcyase_NAD PF00670.21 EST41331.1 - 5.6e-05 23.3 1.4 0.53 10.3 0.0 3.3 3 0 0 3 3 3 2 S-adenosyl-L-homocysteine hydrolase, NAD binding domain FAD_binding_3 PF01494.19 EST41331.1 - 7.2e-05 22.2 1.7 0.0074 15.6 0.4 2.2 2 0 0 2 2 2 1 FAD binding domain PALP PF00291.25 EST41331.1 - 0.00011 21.7 0.6 0.0064 15.9 0.0 2.7 3 0 0 3 3 3 1 Pyridoxal-phosphate dependent enzyme GIDA PF01134.22 EST41331.1 - 0.00026 20.2 8.6 0.0015 17.7 1.0 2.8 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EST41331.1 - 0.00075 18.7 4.4 0.00075 18.7 4.4 2.8 3 0 0 3 3 3 1 FAD binding domain FAD_binding_6 PF00970.24 EST41331.1 - 0.0009 19.6 0.0 0.002 18.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain FMO-like PF00743.19 EST41331.1 - 0.0019 16.7 0.1 0.41 9.0 0.0 2.3 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like XdhC_C PF13478.6 EST41331.1 - 0.002 18.6 0.7 0.0036 17.8 0.0 1.8 2 0 0 2 2 1 1 XdhC Rossmann domain DAO PF01266.24 EST41331.1 - 0.003 17.2 6.6 0.4 10.2 1.3 3.3 3 1 0 3 3 3 2 FAD dependent oxidoreductase ELFV_dehydrog PF00208.21 EST41331.1 - 0.0069 16.1 0.2 2.2 7.9 0.0 2.4 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 3HCDH_N PF02737.18 EST41331.1 - 0.01 15.7 3.5 1.7 8.5 1.1 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EST41331.1 - 0.013 16.1 3.6 4.7 7.8 0.0 3.1 3 0 0 3 3 2 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EST41331.1 - 0.014 15.5 2.6 0.18 11.9 0.0 2.7 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase Fer2_3 PF13085.6 EST41331.1 - 0.015 15.3 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain NAD_binding_6 PF08030.12 EST41331.1 - 0.032 14.4 0.0 0.12 12.5 0.0 2.0 1 1 0 1 1 1 0 Ferric reductase NAD binding domain IlvN PF07991.12 EST41331.1 - 0.032 13.8 1.0 1.1 8.8 0.2 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_Gly3P_dh_N PF01210.23 EST41331.1 - 0.042 13.8 0.2 0.57 10.2 0.1 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Amino_oxidase PF01593.24 EST41331.1 - 0.072 12.4 0.4 0.17 11.2 0.5 1.5 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase YjeF_N PF03853.15 EST41331.1 - 0.2 11.5 0.7 2.8 7.8 0.1 2.3 2 0 0 2 2 2 0 YjeF-related protein N-terminus UDPG_MGDP_dh_N PF03721.14 EST41331.1 - 0.55 9.8 3.0 7.4 6.1 0.2 2.7 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Lycopene_cycl PF05834.12 EST41331.1 - 1.5 7.8 6.7 0.41 9.6 1.5 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein RNA_pol_Rpb5_C PF01191.19 EST41332.1 - 2.1e-13 49.9 0.1 4.7e-13 48.8 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain Ten1 PF12658.7 EST41332.1 - 0.055 13.4 0.1 0.069 13.1 0.1 1.3 1 0 0 1 1 1 0 Telomere capping, CST complex subunit RRM_3 PF08777.11 EST41333.1 - 7.2e-12 45.2 0.3 1.1e-11 44.7 0.3 1.2 1 0 0 1 1 1 1 RNA binding motif B5 PF03484.15 EST41334.1 - 0.018 15.4 0.0 0.061 13.6 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetase B5 domain DUF3782 PF12644.7 EST41337.1 - 0.049 13.8 0.8 0.9 9.7 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3782) SHIPPO-rpt PF07004.12 EST41338.1 - 3.9e-61 201.3 140.8 0.00012 22.8 0.2 23.6 24 0 0 24 24 24 19 Sperm-tail PG-rich repeat Pcc1 PF09341.10 EST41339.1 - 0.0003 20.9 0.0 0.00039 20.5 0.0 1.2 1 0 0 1 1 1 1 Transcription factor Pcc1 Fib_alpha PF08702.10 EST41340.1 - 0.36 11.0 8.5 0.44 10.7 3.0 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 EST41340.1 - 9.5 6.8 10.6 0.35 11.4 0.6 2.5 2 1 0 2 2 2 0 Protein of unknown function DUF16 DUF903 PF06004.12 EST41341.1 - 1 9.3 23.4 9 6.3 0.4 7.3 6 2 2 8 8 8 0 Bacterial protein of unknown function (DUF903) DUF1659 PF07872.11 EST41341.1 - 6.3 6.5 6.6 6.7 6.5 0.2 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1659) SHIPPO-rpt PF07004.12 EST41342.1 - 8.8e-30 102.2 77.4 0.00053 20.8 0.1 12.7 12 1 0 12 12 12 12 Sperm-tail PG-rich repeat SHIPPO-rpt PF07004.12 EST41343.1 - 1.1e-05 26.1 1.4 0.076 14.0 0.0 3.0 3 1 0 3 3 3 2 Sperm-tail PG-rich repeat PC4 PF02229.16 EST41343.1 - 0.024 14.2 0.2 0.087 12.5 0.2 1.9 1 1 0 1 1 1 0 Transcriptional Coactivator p15 (PC4) Myb_DNA-binding PF00249.31 EST41345.1 - 0.0013 18.9 0.1 0.0029 17.8 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST41345.1 - 0.0045 17.2 0.1 0.014 15.7 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain K-box PF01486.17 EST41345.1 - 0.019 15.1 0.7 0.036 14.2 0.7 1.4 1 0 0 1 1 1 0 K-box region DegQ PF08181.11 EST41345.1 - 0.055 13.6 4.4 3.2 7.9 0.8 3.3 3 0 0 3 3 3 0 DegQ (SacQ) family SANT_DAMP1_like PF16282.5 EST41345.1 - 0.19 11.9 0.8 1.8 8.8 0.8 2.3 1 1 0 1 1 1 0 SANT/Myb-like domain of DAMP1 GAS PF13851.6 EST41346.1 - 0.0098 15.3 18.7 0.35 10.2 12.6 2.4 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding JIP_LZII PF16471.5 EST41346.1 - 0.011 15.8 3.2 0.011 15.8 3.2 3.0 3 1 1 4 4 3 0 JNK-interacting protein leucine zipper II Cnn_1N PF07989.11 EST41346.1 - 0.015 15.4 11.4 1.2 9.4 0.2 3.0 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 FAM76 PF16046.5 EST41346.1 - 0.046 13.1 12.9 0.068 12.5 12.9 1.2 1 0 0 1 1 1 0 FAM76 protein T3SchapCesA PF11439.8 EST41346.1 - 0.051 13.7 2.5 1.7 8.8 0.3 2.7 2 1 0 2 2 2 0 Type III secretion system filament chaperone CesA Spc7 PF08317.11 EST41346.1 - 0.06 12.2 17.5 0.067 12.1 9.6 2.1 1 1 0 2 2 2 0 Spc7 kinetochore protein KIAA1430 PF13879.6 EST41346.1 - 0.1 13.4 11.3 3.1 8.6 9.1 3.0 1 1 1 2 2 2 0 KIAA1430 homologue CENP-F_leu_zip PF10473.9 EST41346.1 - 0.17 11.9 18.3 0.062 13.3 13.2 2.4 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF16 PF01519.16 EST41346.1 - 0.21 12.1 17.6 2.2 8.8 6.9 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 Lectin_N PF03954.14 EST41346.1 - 0.38 10.5 12.2 5.8 6.7 0.1 2.7 1 1 0 2 2 2 0 Hepatic lectin, N-terminal domain PRKG1_interact PF15898.5 EST41346.1 - 0.45 11.4 16.3 0.58 11.1 8.7 2.9 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain YabA PF06156.13 EST41346.1 - 2.1 9.0 16.1 13 6.5 0.5 3.3 2 1 2 4 4 3 0 Initiation control protein YabA T3SSipB PF16535.5 EST41346.1 - 2.7 8.5 18.0 7.3 7.0 17.4 2.0 1 1 0 1 1 1 0 Type III cell invasion protein SipB Jnk-SapK_ap_N PF09744.9 EST41346.1 - 3.4 7.9 22.6 0.29 11.3 10.8 3.0 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 Fungal_TACC PF12709.7 EST41346.1 - 3.7 8.0 13.0 5.4 7.5 1.6 3.7 2 1 2 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins T3SS_needle_E PF08988.10 EST41346.1 - 4.2 7.6 10.1 1.8 8.8 0.8 3.5 2 1 0 3 3 3 0 Type III secretion system, cytoplasmic E component of needle Tup_N PF08581.10 EST41346.1 - 5.8 7.3 13.5 1.8 8.9 0.6 3.2 1 1 2 3 3 3 0 Tup N-terminal Pribosyltran PF00156.27 EST41347.1 - 8.4e-09 35.1 0.0 1.2e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GAS PF13851.6 EST41348.1 - 0.00019 20.8 6.7 0.00019 20.8 6.7 4.4 2 1 2 4 4 4 2 Growth-arrest specific micro-tubule binding OmpH PF03938.14 EST41348.1 - 0.0027 18.1 8.1 0.0027 18.1 8.1 4.9 2 2 4 6 6 6 1 Outer membrane protein (OmpH-like) Cnn_1N PF07989.11 EST41348.1 - 0.018 15.2 4.0 0.018 15.2 4.0 6.1 5 1 1 6 6 6 0 Centrosomin N-terminal motif 1 DUF2760 PF10816.8 EST41348.1 - 0.21 11.5 4.2 0.32 10.8 1.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2760) PK PF00224.21 EST41349.1 - 0.00023 20.2 0.3 0.00037 19.5 0.0 1.4 2 0 0 2 2 2 1 Pyruvate kinase, barrel domain START PF01852.19 EST41350.1 - 1.4e-08 34.4 0.0 2.2e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 START domain TMA7 PF09072.10 EST41351.1 - 6.8e-11 42.8 15.3 7.4e-11 42.7 15.3 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 HAD_2 PF13419.6 EST41353.1 - 1.6e-26 93.4 0.1 2.1e-26 93.1 0.1 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EST41353.1 - 1e-15 58.6 1.5 2.8e-12 47.4 0.0 2.1 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EST41353.1 - 1.4e-05 25.5 0.0 2.1e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EST41353.1 - 0.00033 20.7 0.7 0.058 13.5 0.7 3.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EST41353.1 - 0.00081 19.4 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Put_Phosphatase PF06888.12 EST41353.1 - 0.017 14.5 0.0 0.022 14.2 0.0 1.1 1 0 0 1 1 1 0 Putative Phosphatase Cystatin PF00031.21 EST41353.1 - 0.072 13.4 0.1 0.12 12.6 0.1 1.3 1 0 0 1 1 1 0 Cystatin domain Hydrolase_3 PF08282.12 EST41353.1 - 0.19 11.4 3.0 8.6 6.0 0.0 2.6 3 1 0 3 3 3 0 haloacid dehalogenase-like hydrolase Aminotran_4 PF01063.19 EST41354.1 - 3.1e-26 92.6 0.0 3.8e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Pkinase PF00069.25 EST41355.1 - 2.1e-13 50.3 0.0 2.6e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 EST41355.1 - 1.9e-09 37.4 0.2 2.8e-09 36.8 0.2 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 EST41355.1 - 8.9e-06 25.2 0.0 1.7e-05 24.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase FTA2 PF13095.6 EST41355.1 - 0.00075 19.2 0.1 0.0016 18.1 0.1 1.5 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 DUF4135 PF13575.6 EST41355.1 - 0.0016 17.8 0.0 0.0022 17.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) Choline_kinase PF01633.20 EST41355.1 - 0.12 11.9 5.9 1.1 8.8 0.8 2.5 2 1 1 3 3 3 0 Choline/ethanolamine kinase SHIPPO-rpt PF07004.12 EST41356.1 - 8.6e-27 92.8 24.6 2.8e-05 24.8 0.3 6.3 6 0 0 6 6 6 6 Sperm-tail PG-rich repeat ECR1_N PF14382.6 EST41356.1 - 3.1e-06 26.9 6.1 10 6.0 0.0 6.1 5 1 1 6 6 6 4 Exosome complex exonuclease RRP4 N-terminal region DUF1489 PF07370.11 EST41357.1 - 0.0082 15.9 0.0 5.4 6.8 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1489) SWIRM PF04433.17 EST41357.1 - 0.013 15.8 1.1 0.013 15.8 1.1 3.6 4 0 0 4 4 4 0 SWIRM domain Nas2_N PF18265.1 EST41358.1 - 3.9 7.5 12.4 0.26 11.2 1.2 4.7 4 0 0 4 4 4 0 Nas2 N_terminal domain Myb_DNA-bind_6 PF13921.6 EST41360.1 - 3.3e-08 33.7 1.7 7.3e-05 22.9 0.6 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EST41360.1 - 0.004 17.3 1.0 2.1 8.6 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain SHIPPO-rpt PF07004.12 EST41363.1 - 4e-19 68.6 27.4 8.3e-05 23.3 0.1 6.5 6 1 0 6 6 6 6 Sperm-tail PG-rich repeat PASTA PF03793.19 EST41364.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 PASTA domain MFS_1 PF07690.16 EST41367.1 - 2.4e-27 95.8 26.9 9.2e-22 77.4 8.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MSP7_C PF12948.7 EST41367.1 - 2.9 8.6 8.4 6.1 7.5 8.4 1.4 1 0 0 1 1 1 0 MSP7-like protein C-terminal domain HEAT PF02985.22 EST41368.1 - 6.6e-06 26.0 0.7 0.096 13.0 0.2 4.2 2 1 1 3 3 3 2 HEAT repeat HEAT_2 PF13646.6 EST41368.1 - 2.6e-05 24.5 0.3 0.11 12.9 0.1 3.6 2 1 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 EST41368.1 - 0.049 14.2 0.1 0.71 10.4 0.0 2.9 2 1 1 3 3 3 0 HEAT-like repeat Cohesin_HEAT PF12765.7 EST41368.1 - 0.69 10.3 4.2 0.97 9.8 0.1 3.4 3 1 1 4 4 4 0 HEAT repeat associated with sister chromatid cohesion DUF4042 PF13251.6 EST41368.1 - 0.76 9.4 10.6 0.97 9.1 0.1 4.6 5 1 1 6 6 6 0 Domain of unknown function (DUF4042) Pro_isomerase PF00160.21 EST41369.1 - 3.6e-44 150.8 0.7 4.1e-44 150.6 0.7 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ATP_bind_1 PF03029.17 EST41370.1 - 3.7e-41 141.5 0.1 4.4e-41 141.2 0.1 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 EST41370.1 - 0.00013 22.5 0.2 0.00067 20.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain MeaB PF03308.16 EST41370.1 - 0.0016 17.5 0.0 0.003 16.6 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 EST41370.1 - 0.015 14.9 0.0 0.023 14.3 0.0 1.5 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 EST41370.1 - 0.017 15.2 0.0 0.057 13.5 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 EST41370.1 - 0.02 14.6 0.0 0.039 13.7 0.0 1.5 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 EST41370.1 - 0.022 14.3 0.0 0.58 9.7 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain NB-ARC PF00931.22 EST41370.1 - 0.023 13.9 0.1 0.055 12.6 0.0 1.7 1 1 1 2 2 2 0 NB-ARC domain Pox_A32 PF04665.12 EST41370.1 - 0.036 13.5 0.5 0.1 12.0 0.1 1.8 2 1 0 2 2 2 0 Poxvirus A32 protein KAP_NTPase PF07693.14 EST41370.1 - 0.037 13.3 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain ArsA_ATPase PF02374.15 EST41370.1 - 0.038 13.2 0.0 0.074 12.2 0.0 1.5 1 0 0 1 1 1 0 Anion-transporting ATPase CbiA PF01656.23 EST41370.1 - 0.044 13.9 0.0 0.049 13.7 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain KTI12 PF08433.10 EST41370.1 - 0.052 13.0 0.0 0.081 12.4 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF2164 PF09932.9 EST41370.1 - 0.054 13.6 0.2 0.19 11.8 0.2 2.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2164) PRK PF00485.18 EST41370.1 - 0.073 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA PF00004.29 EST41370.1 - 0.075 13.5 0.1 0.17 12.3 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EST41370.1 - 0.077 13.2 0.2 0.17 12.2 0.2 1.8 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 EST41370.1 - 0.081 12.5 0.0 9.1 5.8 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF5398 PF17376.2 EST41370.1 - 0.088 13.4 0.1 0.16 12.6 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5398) TsaE PF02367.17 EST41370.1 - 0.16 11.9 0.1 0.38 10.8 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE E2F_TDP PF02319.20 EST41371.1 - 1.9e-14 53.4 0.1 7.2e-07 29.2 0.0 2.1 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 EST41371.1 - 1.1e-06 28.4 0.0 0.00034 20.5 0.0 2.2 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB UBA_2 PF08587.11 EST41371.1 - 0.12 12.5 0.0 12 6.1 0.0 2.7 2 1 0 2 2 2 0 Ubiquitin associated domain (UBA) DIRP PF06584.13 EST41372.1 - 0.4 10.9 4.9 0.32 11.2 0.5 2.2 1 1 1 2 2 2 0 DIRP Metallophos PF00149.28 EST41373.1 - 3.3e-35 122.4 0.0 5.3e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase WD40 PF00400.32 EST41375.1 - 1.4e-16 60.5 3.3 0.0037 18.1 0.0 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat BBS2_Mid PF14783.6 EST41375.1 - 0.019 15.0 4.8 20 5.3 0.0 4.7 4 1 2 6 6 6 0 Ciliary BBSome complex subunit 2, middle region Mcl1_mid PF12341.8 EST41375.1 - 0.026 13.9 0.3 0.2 10.9 0.2 2.6 1 1 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region HPS3_N PF14761.6 EST41375.1 - 0.068 12.7 4.8 3 7.3 0.1 3.8 2 2 2 4 4 4 0 Hermansky-Pudlak syndrome 3 PQQ_3 PF13570.6 EST41375.1 - 0.16 12.5 0.3 9.5 6.9 0.0 3.3 4 0 0 4 4 4 0 PQQ-like domain Thioredoxin_6 PF13848.6 EST41376.1 - 3.9e-07 30.2 10.8 5.9e-06 26.3 4.3 2.2 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_9 PF14595.6 EST41376.1 - 0.073 12.8 0.1 0.81 9.5 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin DUF4269 PF14091.6 EST41377.1 - 1.2 9.3 5.8 6.8 6.9 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4269) ATG16 PF08614.11 EST41378.1 - 0.0024 18.1 20.3 0.0024 18.1 20.3 4.3 1 1 2 4 4 4 1 Autophagy protein 16 (ATG16) Uso1_p115_C PF04871.13 EST41378.1 - 0.0067 16.8 12.5 0.0067 16.8 12.5 4.7 1 1 4 5 5 5 2 Uso1 / p115 like vesicle tethering protein, C terminal region PKcGMP_CC PF16808.5 EST41378.1 - 0.019 14.8 0.0 0.019 14.8 0.0 4.5 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Phenyl_P_gamma PF09662.10 EST41378.1 - 0.14 12.4 3.9 1.5 9.0 0.7 3.3 2 2 1 3 3 3 0 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) Fez1 PF06818.15 EST41378.1 - 6.5 7.2 60.3 7.9 6.9 13.5 3.3 1 1 2 3 3 3 0 Fez1 NMT PF01233.19 EST41378.1 - 7.9 6.3 10.9 6.4 6.6 0.7 3.0 2 1 0 3 3 3 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Spc7 PF08317.11 EST41378.1 - 8.6 5.1 67.0 7 5.4 17.3 3.4 1 1 3 4 4 4 0 Spc7 kinetochore protein APG6_N PF17675.1 EST41379.1 - 0.0017 18.9 10.4 0.0017 18.9 10.4 1.9 1 1 1 2 2 2 1 Apg6 coiled-coil region Spc7 PF08317.11 EST41379.1 - 0.014 14.3 11.3 0.026 13.4 11.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein HMMR_N PF15905.5 EST41379.1 - 0.022 14.2 12.0 0.027 14.0 12.0 1.0 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Fez1 PF06818.15 EST41379.1 - 0.032 14.7 9.7 0.022 15.2 6.6 1.9 1 1 0 1 1 1 0 Fez1 CortBP2 PF09727.9 EST41379.1 - 0.045 13.7 8.2 0.025 14.5 6.6 1.5 2 0 0 2 2 2 0 Cortactin-binding protein-2 ERM PF00769.19 EST41379.1 - 0.07 12.9 8.4 0.24 11.2 6.2 2.0 2 0 0 2 2 2 0 Ezrin/radixin/moesin family RraB PF06877.11 EST41379.1 - 0.12 13.1 4.2 0.21 12.3 4.2 1.5 1 0 0 1 1 1 0 Regulator of ribonuclease activity B BST2 PF16716.5 EST41379.1 - 0.18 12.4 13.5 0.041 14.5 3.1 2.9 1 1 1 3 3 3 0 Bone marrow stromal antigen 2 CLZ PF16526.5 EST41379.1 - 0.92 9.9 6.9 12 6.3 1.0 2.7 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SlyX PF04102.12 EST41379.1 - 1.5 9.4 12.2 0.09 13.4 2.0 2.7 2 1 1 3 3 3 0 SlyX Bap31_Bap29_C PF18035.1 EST41379.1 - 1.7 8.7 0.0 1.7 8.7 0.0 3.6 3 1 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF4250 PF14056.6 EST41379.1 - 2 8.5 6.2 5.7 7.0 0.1 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4250) PRKG1_interact PF15898.5 EST41379.1 - 4.9 8.1 13.6 8.8 7.3 5.3 3.0 1 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain DHR10 PF18595.1 EST41379.1 - 7.5 6.6 14.4 2.4 8.3 0.8 2.9 2 1 0 3 3 3 0 Designed helical repeat protein 10 domain PAP_assoc PF03828.19 EST41380.1 - 0.0047 17.1 0.1 0.0047 17.1 0.1 2.3 2 0 0 2 2 2 1 Cid1 family poly A polymerase LPD13 PF18825.1 EST41380.1 - 0.12 12.2 1.4 0.54 10.0 0.1 2.3 1 1 2 3 3 3 0 Large polyvalent protein-associated domain 13 DUF3177 PF11375.8 EST41380.1 - 0.13 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3177) DUF5375 PF17345.2 EST41380.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5375) Epimerase PF01370.21 EST41381.1 - 7.4e-17 61.6 0.0 1.1e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EST41381.1 - 1.3e-09 37.9 0.1 1.8e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EST41381.1 - 1.5e-09 37.4 0.0 4.6e-09 35.8 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 EST41381.1 - 6.2e-09 35.3 0.0 1.4e-08 34.1 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EST41381.1 - 6.5e-08 32.7 0.0 1.7e-07 31.4 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EST41381.1 - 0.00033 20.9 0.0 0.00078 19.7 0.0 1.7 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 EST41381.1 - 0.018 15.0 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 KR domain DUF1952 PF09189.10 EST41382.1 - 0.064 13.1 2.5 0.099 12.5 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1952) START PF01852.19 EST41383.1 - 1.4e-11 44.2 0.0 1.9e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 START domain AAA_lid_10 PF17872.1 EST41383.1 - 0.056 13.6 0.3 0.21 11.7 0.1 1.9 2 0 0 2 2 2 0 AAA lid domain Glucokinase PF02685.16 EST41384.1 - 6.4e-59 199.5 0.0 7.3e-59 199.3 0.0 1.0 1 0 0 1 1 1 1 Glucokinase ROK PF00480.20 EST41384.1 - 6e-10 39.1 0.0 1.5e-09 37.8 0.0 1.6 1 1 0 1 1 1 1 ROK family GalKase_gal_bdg PF10509.9 EST41386.1 - 3.6e-15 55.2 0.0 1.5e-14 53.3 0.0 2.0 2 0 0 2 2 2 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 EST41386.1 - 1.6e-12 47.4 2.5 5.7e-12 45.7 2.5 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EST41386.1 - 1.2e-09 38.4 0.2 6.7e-09 36.0 0.1 2.3 2 0 0 2 2 2 1 GHMP kinases C terminal Endonuclease_1 PF04231.13 EST41387.1 - 2.3e-27 96.2 0.8 3.2e-27 95.7 0.8 1.1 1 0 0 1 1 1 1 Endonuclease I Fijivirus_P9-2 PF06837.11 EST41390.1 - 0.016 14.7 0.9 0.016 14.7 0.9 1.7 2 0 0 2 2 2 0 Fijivirus P9-2 protein HrcA PF01628.21 EST41390.1 - 0.034 14.1 0.0 0.047 13.6 0.0 1.2 1 0 0 1 1 1 0 HrcA protein C terminal domain DUF2542 PF10808.8 EST41390.1 - 0.2 12.2 2.6 1.5 9.3 2.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2542) Ctr PF04145.15 EST41390.1 - 1.2 9.7 6.6 0.089 13.4 1.3 1.7 1 1 1 2 2 2 0 Ctr copper transporter family UCH PF00443.29 EST41391.1 - 2.3e-27 96.1 4.3 2.3e-27 96.1 4.3 1.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EST41391.1 - 5.7e-10 39.3 7.3 1.1e-08 35.1 7.3 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-RING_9 PF13901.6 EST41391.1 - 1 9.3 11.2 11 6.0 0.4 3.8 2 1 1 3 3 3 0 Putative zinc-RING and/or ribbon SPA PF08616.10 EST41392.1 - 0.052 13.5 2.1 0.095 12.7 0.1 2.4 2 1 1 3 3 3 0 Stabilization of polarity axis FH2 PF02181.23 EST41393.1 - 3.3e-41 141.6 19.4 5.8e-41 140.8 19.4 1.3 1 0 0 1 1 1 1 Formin Homology 2 Domain RNA_pol_N PF01194.17 EST41394.1 - 5.7e-29 100.2 1.8 6.6e-29 100.0 1.8 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 EST41394.1 - 0.028 14.7 0.9 0.048 13.9 0.9 1.4 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) FlxA PF14282.6 EST41395.1 - 9.9 6.2 15.7 0.38 10.8 0.4 3.0 3 1 0 3 3 3 0 FlxA-like protein Palm_thioest PF02089.15 EST41396.1 - 1.2e-54 185.7 0.1 1.4e-54 185.5 0.1 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 EST41396.1 - 5.1e-06 26.2 0.0 8.9e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 EST41396.1 - 0.025 13.8 0.0 0.054 12.8 0.0 1.6 1 1 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 EST41396.1 - 0.034 13.9 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein DUF915 PF06028.11 EST41396.1 - 0.045 13.1 0.1 4.7 6.5 0.0 2.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Peptidase_S9 PF00326.21 EST41396.1 - 0.057 12.9 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EST41396.1 - 0.069 12.8 0.2 0.19 11.4 0.1 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Pkinase PF00069.25 EST41397.1 - 2.2e-24 86.3 1.5 4.1e-22 78.8 1.2 2.4 1 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST41397.1 - 1.3e-13 50.9 1.2 2e-12 47.0 0.1 2.1 1 1 1 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EST41397.1 - 0.0082 16.1 0.1 0.014 15.4 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EST41397.1 - 0.015 14.9 0.2 0.034 13.8 0.2 1.6 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 EST41397.1 - 0.025 13.9 0.0 0.049 12.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 EST41397.1 - 0.029 13.7 0.4 0.051 12.9 0.4 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EST41397.1 - 0.037 13.6 1.2 0.064 12.8 1.2 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase CAP160 PF07918.11 EST41397.1 - 0.26 11.0 0.4 0.53 10.1 0.4 1.5 1 0 0 1 1 1 0 CAP160 repeat DUF2164 PF09932.9 EST41398.1 - 0.064 13.3 1.9 0.31 11.1 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2164) DUF45 PF01863.17 EST41398.1 - 0.39 10.7 3.7 0.69 9.9 3.4 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF45 Thioredoxin_8 PF13905.6 EST41399.1 - 2.4e-09 37.4 0.0 3.9e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 EST41399.1 - 1.4e-08 34.6 0.0 1.9e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EST41399.1 - 3.6e-08 33.2 0.0 4.8e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.6 EST41399.1 - 0.0013 19.2 0.0 0.0021 18.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 EST41399.1 - 0.055 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin PF00085.20 EST41399.1 - 0.059 13.4 0.0 0.49 10.4 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin DUF393 PF04134.12 EST41399.1 - 0.087 14.2 0.0 0.12 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF393 HhH-GPD PF00730.25 EST41401.1 - 6.6e-16 58.7 0.0 1e-15 58.1 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EST41401.1 - 1.9e-05 24.3 0.0 4.6e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif PHF5 PF03660.14 EST41402.1 - 1.3 9.3 23.5 2.1 8.6 23.5 1.4 1 1 0 1 1 1 0 PHF5-like protein WD40_like PF17005.5 EST41403.1 - 2.6e-08 33.6 20.5 0.00022 20.7 7.8 4.3 1 1 1 4 4 4 3 WD40-like domain ANAPC4_WD40 PF12894.7 EST41403.1 - 3.5e-07 30.4 0.0 0.21 11.9 0.0 5.9 3 2 4 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EST41403.1 - 1.3e-05 25.9 0.6 0.27 12.2 0.0 5.2 4 2 0 4 4 4 1 WD domain, G-beta repeat PQQ_3 PF13570.6 EST41403.1 - 0.0025 18.3 0.0 64 4.2 0.0 4.7 4 0 0 4 4 4 0 PQQ-like domain Frtz PF11768.8 EST41403.1 - 0.0048 15.3 2.2 0.54 8.5 0.0 3.9 4 1 0 4 4 4 1 WD repeat-containing and planar cell polarity effector protein Fritz Utp8 PF10395.9 EST41403.1 - 0.008 14.7 5.6 0.046 12.2 0.0 2.2 2 0 0 2 2 2 1 Utp8 family Histone PF00125.24 EST41404.1 - 2e-40 138.2 5.6 2.3e-40 138.0 5.6 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EST41404.1 - 2.2e-05 24.7 0.0 5.1e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EST41404.1 - 7.2e-05 22.9 1.7 0.00015 21.9 0.1 2.1 1 1 1 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EST41404.1 - 0.00086 19.9 0.9 0.00086 19.9 0.9 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain TFIID-31kDa PF02291.15 EST41404.1 - 0.078 13.0 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 EST41405.1 - 3.6e-31 108.2 4.8 4.3e-31 108.0 4.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EST41405.1 - 3.3e-06 27.2 1.0 5.9e-06 26.4 0.1 1.8 1 1 1 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EST41405.1 - 0.0011 19.3 0.8 0.0018 18.6 0.2 1.6 2 0 0 2 2 2 1 CENP-S protein Nepo_coat_C PF03688.14 EST41405.1 - 0.0086 15.9 0.0 0.01 15.7 0.0 1.1 1 0 0 1 1 1 1 Nepovirus coat protein, C-terminal domain TFIID-31kDa PF02291.15 EST41405.1 - 0.0094 16.0 0.1 0.016 15.3 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit DUF3509 PF12021.8 EST41405.1 - 0.83 9.5 5.0 0.28 10.9 0.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3509) UQ_con PF00179.26 EST41406.1 - 7.5e-43 145.5 0.1 8.7e-43 145.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EST41406.1 - 0.00027 20.7 0.0 0.00038 20.2 0.0 1.3 1 1 0 1 1 1 1 Prokaryotic E2 family B Ras PF00071.22 EST41407.1 - 1e-05 25.2 0.0 1.5e-05 24.6 0.0 1.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EST41407.1 - 0.0032 17.7 0.0 0.0052 17.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 EST41407.1 - 0.0094 16.2 0.1 0.08 13.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EST41407.1 - 0.013 15.8 0.0 0.028 14.8 0.0 1.5 1 1 0 1 1 1 0 RNA helicase MMR_HSR1 PF01926.23 EST41407.1 - 0.022 14.8 0.0 0.054 13.6 0.0 1.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_24 PF13479.6 EST41407.1 - 0.037 13.7 0.0 0.074 12.8 0.0 1.3 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 EST41407.1 - 0.084 12.2 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.12 EST41407.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 EST41407.1 - 0.16 12.1 0.0 0.18 12.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain Lactamase_B PF00753.27 EST41408.1 - 7.6e-17 62.0 0.1 1.1e-16 61.5 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EST41408.1 - 8.3e-06 25.5 1.1 6.4e-05 22.6 1.1 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain PDEase_II PF02112.15 EST41408.1 - 0.004 16.3 0.2 0.0077 15.4 0.2 1.4 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II Cas_Csn2 PF09711.10 EST41408.1 - 0.016 14.9 0.6 0.024 14.3 0.6 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csn2) HTH_WhiA PF02650.14 EST41408.1 - 0.13 12.6 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 WhiA C-terminal HTH domain Pox_Ag35 PF03286.14 EST41409.1 - 0.013 15.3 2.1 0.013 15.3 2.1 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein RNase_PH_C PF03725.15 EST41410.1 - 0.062 13.3 0.0 0.17 11.9 0.0 1.7 2 0 0 2 2 2 0 3' exoribonuclease family, domain 2 DUF2202 PF09968.9 EST41410.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein domain (DUF2202) Endonuclease_1 PF04231.13 EST41411.1 - 3.3e-26 92.4 1.7 4.3e-26 92.0 1.7 1.1 1 0 0 1 1 1 1 Endonuclease I ubiquitin PF00240.23 EST41415.1 - 4e-17 61.7 2.3 4.6e-17 61.5 2.3 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EST41415.1 - 4.8e-07 29.5 1.2 5.1e-07 29.4 1.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 EST41415.1 - 1.9e-05 24.7 0.3 5.9e-05 23.1 0.3 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 EST41415.1 - 0.00019 21.3 0.3 0.0002 21.2 0.3 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 EST41415.1 - 0.013 15.9 0.2 0.016 15.6 0.2 1.3 1 1 0 1 1 1 0 Ubiquitin-like domain UN_NPL4 PF11543.8 EST41415.1 - 0.041 14.4 0.6 0.054 14.0 0.6 1.2 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 V-SNARE_C PF12352.8 EST41416.1 - 0.002 18.4 2.2 0.011 16.0 0.5 2.3 1 1 1 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EST41416.1 - 0.0094 15.9 0.2 0.037 14.0 0.0 1.8 1 1 1 2 2 2 1 Sec20 ComR_TPR PF18710.1 EST41416.1 - 0.053 13.1 1.3 0.062 12.8 1.3 1.1 1 0 0 1 1 1 0 ComR tetratricopeptide Histidinol_dh PF00815.20 EST41418.1 - 0.026 13.5 0.4 0.1 11.6 0.4 2.0 1 0 0 1 1 1 0 Histidinol dehydrogenase DUF2569 PF10754.9 EST41420.1 - 0.16 12.4 4.9 0.21 12.0 4.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2569) SET PF00856.28 EST41422.1 - 8.8e-20 71.8 0.1 9.2e-19 68.4 0.1 2.3 1 1 0 1 1 1 1 SET domain TolB_N PF04052.13 EST41423.1 - 0.02 15.0 0.1 0.1 12.8 0.0 2.1 1 1 1 2 2 2 0 TolB amino-terminal domain CENP-N PF05238.13 EST41424.1 - 0.81 8.9 3.0 16 4.6 0.5 2.2 1 1 0 2 2 2 0 Kinetochore protein CHL4 like Tup_N PF08581.10 EST41425.1 - 0.01 16.1 9.3 0.01 16.1 9.3 8.0 6 1 2 8 8 8 0 Tup N-terminal VraX PF17412.2 EST41426.1 - 0.1 12.2 1.1 0.34 10.6 0.6 2.1 1 1 1 2 2 2 0 Family of unknown function Pkinase PF00069.25 EST41427.1 - 1.4e-07 31.2 0.2 4.6e-07 29.5 0.2 2.0 1 0 0 1 1 1 1 Protein kinase domain Myb_DNA-binding PF00249.31 EST41428.1 - 1.5e-05 25.1 7.0 0.021 15.0 0.4 2.7 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST41428.1 - 0.0013 19.0 7.4 0.18 12.1 1.3 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain HTH_32 PF13565.6 EST41428.1 - 0.0063 17.1 0.2 0.05 14.2 0.1 2.0 1 1 1 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 EST41428.1 - 0.062 13.1 0.2 0.24 11.2 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain DUF3896 PF13035.6 EST41428.1 - 1.3 9.3 6.9 0.42 10.8 0.7 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF3896) Skp1 PF01466.19 EST41428.1 - 2.8 8.1 6.2 3.6 7.8 0.1 3.2 3 1 0 3 3 3 0 Skp1 family, dimerisation domain Glucokinase PF02685.16 EST41430.1 - 3.6e-59 200.3 0.0 4.1e-59 200.1 0.0 1.0 1 0 0 1 1 1 1 Glucokinase ROK PF00480.20 EST41430.1 - 2.4e-11 43.7 0.1 3.1e-11 43.3 0.1 1.1 1 0 0 1 1 1 1 ROK family Palm_thioest PF02089.15 EST41431.1 - 4.3e-56 190.5 0.1 4.9e-56 190.3 0.1 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 EST41431.1 - 2.9e-05 23.7 0.3 9.2e-05 22.0 0.3 1.7 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 EST41431.1 - 0.0039 16.9 0.1 0.011 15.3 0.1 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF915 PF06028.11 EST41431.1 - 0.0042 16.4 0.5 3 7.1 0.0 2.8 2 1 1 3 3 3 2 Alpha/beta hydrolase of unknown function (DUF915) Peptidase_S9 PF00326.21 EST41431.1 - 0.011 15.2 0.1 0.39 10.2 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family PGAP1 PF07819.13 EST41431.1 - 0.042 13.6 0.0 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 PGAP1-like protein Abhydrolase_6 PF12697.7 EST41431.1 - 0.18 12.4 0.0 0.28 11.7 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Pkinase PF00069.25 EST41432.1 - 0.0014 18.0 0.1 0.0041 16.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain TP6A_N PF04406.14 EST41433.1 - 2.8e-08 33.6 2.5 5.4e-08 32.7 1.2 2.0 2 0 0 2 2 2 1 Type IIB DNA topoisomerase DUF5043 PF16446.5 EST41433.1 - 0.064 13.3 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5043) VanY PF02557.17 EST41434.1 - 0.0085 15.9 0.1 0.0091 15.8 0.1 1.0 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Phyto_Pns9_10 PF05878.11 EST41435.1 - 0.048 12.8 0.0 0.15 11.1 0.0 1.8 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 MFS_1 PF07690.16 EST41436.1 - 6.8e-26 91.0 19.8 7.8e-26 90.8 19.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EST41436.1 - 4e-13 49.0 13.2 3.5e-11 42.6 5.5 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 EST41436.1 - 3.6e-10 39.0 24.6 1.5e-08 33.7 7.0 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein Myb_DNA-bind_6 PF13921.6 EST41437.1 - 3.3e-06 27.3 1.0 3.3e-06 27.3 1.0 1.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EST41437.1 - 0.05 13.8 0.3 0.05 13.8 0.3 1.8 2 0 0 2 2 2 0 Myb-like DNA-binding domain T7SS_ESX1_EccB PF05108.13 EST41437.1 - 0.24 10.0 0.0 0.29 9.7 0.0 1.0 1 0 0 1 1 1 0 Type VII secretion system ESX-1, transport TM domain B ANAPC4_WD40 PF12894.7 EST41439.1 - 2.5e-06 27.7 0.5 0.0046 17.2 0.3 2.8 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain E2F_TDP PF02319.20 EST41440.1 - 1.5e-06 28.2 0.2 2.3e-06 27.6 0.2 1.3 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 EST41440.1 - 0.00067 19.5 0.0 0.00091 19.1 0.0 1.2 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Rio2_N PF09202.11 EST41440.1 - 0.0067 16.6 0.1 0.01 16.0 0.1 1.3 1 0 0 1 1 1 1 Rio2, N-terminal TFIIE_alpha PF02002.17 EST41440.1 - 0.018 14.9 0.3 0.023 14.6 0.3 1.4 1 1 0 1 1 1 0 TFIIE alpha subunit DUF4423 PF14394.6 EST41440.1 - 0.025 14.3 0.1 0.029 14.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) DUF87 PF01935.17 EST41441.1 - 1.7 8.7 16.3 0.11 12.5 2.3 3.3 3 0 0 3 3 3 0 Helicase HerA, central domain Myb_DNA-binding PF00249.31 EST41442.1 - 1.2e-05 25.4 4.0 0.13 12.5 1.9 3.9 3 2 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST41442.1 - 4.3e-05 23.7 4.3 0.091 13.0 1.5 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain DUF1722 PF08349.11 EST41442.1 - 0.011 16.0 1.6 0.055 13.7 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1722) SANT_DAMP1_like PF16282.5 EST41442.1 - 0.067 13.4 1.2 0.11 12.7 0.1 2.0 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_5 PF13873.6 EST41442.1 - 0.16 12.1 3.0 1.7 8.8 0.3 2.5 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain SHIPPO-rpt PF07004.12 EST41444.1 - 1e-23 83.1 21.2 6.1e-05 23.7 0.4 6.2 6 0 0 6 6 6 6 Sperm-tail PG-rich repeat ECR1_N PF14382.6 EST41444.1 - 2.2e-05 24.1 0.8 5.9 6.8 0.0 4.9 5 0 0 5 5 5 2 Exosome complex exonuclease RRP4 N-terminal region Cpn60_TCP1 PF00118.24 EST41446.1 - 3.3e-130 435.0 13.8 3.7e-130 434.8 13.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ANAPC9 PF12856.7 EST41446.1 - 0.11 12.7 0.3 0.2 11.8 0.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 9 ANAPC15 PF15243.6 EST41447.1 - 0.0076 16.6 0.1 0.013 15.9 0.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 15 Orthopox_A49R PF06489.11 EST41447.1 - 0.16 12.2 1.6 0.55 10.5 0.9 2.1 2 1 1 3 3 3 0 Orthopoxvirus A49R protein NifU PF01106.17 EST41448.1 - 5.6e-18 64.8 0.0 9.6e-18 64.1 0.0 1.3 1 0 0 1 1 1 1 NifU-like domain SecD-TM1 PF13721.6 EST41448.1 - 0.089 13.3 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 SecD export protein N-terminal TM region Ribosomal_S3_C PF00189.20 EST41450.1 - 1.6e-19 70.2 5.5 1.9e-19 70.0 3.8 1.9 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 EST41450.1 - 1.7e-06 27.7 0.0 4e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 KH domain UPF0270 PF06794.12 EST41450.1 - 0.0039 17.2 0.0 0.0072 16.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0270) S-AdoMet_synt_N PF00438.20 EST41450.1 - 0.063 14.0 0.1 0.84 10.4 0.0 2.2 2 0 0 2 2 2 0 S-adenosylmethionine synthetase, N-terminal domain RHINO PF15319.6 EST41451.1 - 0.014 15.5 0.4 0.021 14.9 0.4 1.4 1 0 0 1 1 1 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein Sugar_tr PF00083.24 EST41452.1 - 2.7e-52 178.1 39.2 3.1e-31 108.7 11.5 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EST41452.1 - 9.4e-20 70.8 37.0 4.7e-14 52.1 12.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily YqzM PF14141.6 EST41452.1 - 1.3 9.1 13.8 0.48 10.5 2.7 3.4 2 0 0 2 2 2 0 YqzM-like protein Trimer_CC PF08954.11 EST41453.1 - 1.3 8.7 3.9 12 5.5 0.0 3.1 2 1 1 3 3 3 0 Trimerisation motif Allexi_40kDa PF05549.11 EST41454.1 - 0.13 11.8 4.1 0.14 11.7 3.4 1.3 1 1 0 1 1 1 0 Allexivirus 40kDa protein zf-MIZ PF02891.20 EST41455.1 - 3e-06 26.9 4.0 8.5e-06 25.4 4.0 1.8 1 1 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 EST41455.1 - 0.025 14.4 2.2 0.072 12.9 2.2 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit V-ATPase_C PF03223.15 EST41456.1 - 2.7e-21 76.4 0.2 3.7e-21 75.9 0.2 1.1 1 0 0 1 1 1 1 V-ATPase subunit C KELK PF15796.5 EST41456.1 - 0.29 11.6 0.2 0.29 11.6 0.2 2.7 3 0 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase RNA_pol_I_A49 PF06870.12 EST41457.1 - 3.8e-05 22.7 1.8 0.0075 15.2 0.1 2.5 1 1 0 2 2 2 2 A49-like RNA polymerase I associated factor Leu_zip PF15294.6 EST41458.1 - 0.032 13.7 41.3 0.16 11.5 14.1 2.3 1 1 0 2 2 2 0 Leucine zipper APG6_N PF17675.1 EST41458.1 - 0.3 11.6 50.9 0.12 12.9 11.5 4.1 1 1 2 3 3 3 0 Apg6 coiled-coil region Filament PF00038.21 EST41458.1 - 0.47 10.0 45.5 0.16 11.5 24.2 2.9 1 1 0 2 2 2 0 Intermediate filament protein JIP_LZII PF16471.5 EST41458.1 - 0.54 10.5 18.1 0.56 10.4 0.9 4.4 2 2 0 3 3 3 0 JNK-interacting protein leucine zipper II CENP-F_leu_zip PF10473.9 EST41458.1 - 6.1 6.9 45.1 8.2 6.5 18.5 3.5 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PTAC PF06130.12 EST41460.1 - 0.076 13.2 0.4 0.14 12.3 0.4 1.4 1 0 0 1 1 1 0 Phosphate propanoyltransferase LuxT_C PF18285.1 EST41461.1 - 0.068 13.7 0.2 6.2 7.4 0.1 3.1 3 0 0 3 3 3 0 Tetracycline repressor LuxT C-terminal domain Malic_M PF03949.15 EST41462.1 - 2.1e-84 282.8 0.7 2.8e-84 282.4 0.7 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EST41462.1 - 5.1e-58 195.9 0.0 7.9e-58 195.2 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain BLM10_N PF16547.5 EST41462.1 - 0.15 12.4 0.2 0.33 11.3 0.2 1.6 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, N-terminal Cluap1 PF10234.9 EST41463.1 - 7.2e-51 173.1 10.8 7.2e-51 173.1 10.8 1.6 2 0 0 2 2 2 1 Clusterin-associated protein-1 DUF1664 PF07889.12 EST41463.1 - 0.012 15.7 5.0 0.49 10.4 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HWE_HK PF07536.14 EST41463.1 - 0.02 15.6 0.7 0.057 14.1 0.7 1.8 1 0 0 1 1 1 0 HWE histidine kinase Atg14 PF10186.9 EST41463.1 - 0.21 10.6 8.4 0.42 9.7 8.4 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RNA_pol_L_2 PF13656.6 EST41464.1 - 6.6e-22 77.1 0.0 7.3e-22 76.9 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EST41464.1 - 8e-07 28.4 0.0 9.7e-07 28.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Dzip-like_N PF13815.6 EST41465.1 - 1.8e-12 47.3 1.0 2.9e-12 46.6 1.0 1.3 1 0 0 1 1 1 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf-C2H2 PF00096.26 EST41465.1 - 0.05 14.1 0.4 0.14 12.7 0.4 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type XPA_N PF01286.18 EST41465.1 - 0.057 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 XPA protein N-terminal Myb_DNA-bind_6 PF13921.6 EST41467.1 - 0.0031 17.7 0.2 0.0043 17.3 0.2 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain PHY PF00360.20 EST41467.1 - 0.1 11.9 0.2 0.12 11.7 0.2 1.1 1 0 0 1 1 1 0 Phytochrome region PP2C PF00481.21 EST41468.1 - 8.5e-40 137.0 0.2 2e-38 132.5 0.0 2.1 2 0 0 2 2 2 1 Protein phosphatase 2C DUF4780 PF16012.5 EST41468.1 - 0.006 16.1 0.1 0.011 15.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4780) PP2C_2 PF13672.6 EST41468.1 - 0.019 14.6 0.1 0.19 11.4 0.1 2.3 2 1 0 2 2 2 0 Protein phosphatase 2C SpoIIE PF07228.12 EST41468.1 - 0.13 12.2 0.2 0.39 10.6 0.0 1.9 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) Pkinase PF00069.25 EST41469.1 - 8.7e-26 90.8 0.6 1.3e-25 90.3 0.6 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST41469.1 - 2.4e-19 69.7 0.1 3e-19 69.3 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EST41469.1 - 0.0058 15.6 5.5 0.0082 15.1 5.5 1.1 1 0 0 1 1 1 1 Haspin like kinase domain IZUMO PF15005.6 EST41470.1 - 0.0041 17.6 1.4 0.065 13.7 0.3 2.0 2 0 0 2 2 2 2 Izumo sperm-egg fusion, Ig domain-associated OTU PF02338.19 EST41471.1 - 1.2e-05 25.9 0.1 1.2e-05 25.9 0.1 3.0 2 2 0 2 2 2 1 OTU-like cysteine protease Branch PF02485.21 EST41471.1 - 0.0091 15.5 0.2 0.014 14.9 0.2 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Peptidase_C65 PF10275.9 EST41471.1 - 0.013 14.9 9.1 0.015 14.8 0.3 3.0 1 1 2 3 3 3 0 Peptidase C65 Otubain Choline_kinase PF01633.20 EST41471.1 - 0.045 13.3 5.5 0.059 13.0 5.5 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase LMBR1 PF04791.16 EST41471.1 - 2.4 7.0 7.6 3 6.7 7.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Presenilin PF01080.17 EST41471.1 - 7.2 5.3 4.9 7.5 5.2 4.9 1.1 1 0 0 1 1 1 0 Presenilin CH PF00307.31 EST41472.1 - 0.00016 21.8 1.8 0.00016 21.8 1.8 2.9 2 1 0 3 3 3 1 Calponin homology (CH) domain MAPKK1_Int PF08923.10 EST41472.1 - 0.0096 15.7 0.1 0.021 14.6 0.1 1.6 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting DUF3810 PF12725.7 EST41472.1 - 0.028 13.8 1.6 0.04 13.3 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) ISG65-75 PF11727.8 EST41472.1 - 0.087 12.0 2.1 0.14 11.3 2.1 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein Ras PF00071.22 EST41473.1 - 1.4e-09 37.8 0.0 7.1e-09 35.5 0.0 2.0 1 1 0 1 1 1 1 Ras family CH PF00307.31 EST41473.1 - 8e-07 29.2 0.1 2.1e-06 27.9 0.1 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain AAA_14 PF13173.6 EST41473.1 - 0.006 16.6 0.0 0.021 14.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 EST41473.1 - 0.037 14.2 0.0 1 9.6 0.0 2.3 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Flavodoxin_2 PF02525.17 EST41475.1 - 2.6e-22 79.5 0.0 3e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 EST41475.1 - 0.0025 17.6 0.0 0.0032 17.2 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Inhibitor_I36 PF03995.13 EST41475.1 - 0.027 14.4 0.7 0.07 13.1 0.6 1.7 2 0 0 2 2 2 0 Peptidase inhibitor family I36 HTH_24 PF13412.6 EST41475.1 - 0.05 13.2 0.1 0.082 12.5 0.1 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding OmdA PF13376.6 EST41477.1 - 1.1 9.3 4.1 9.5 6.3 0.7 2.9 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated Mto2_bdg PF12808.7 EST41477.1 - 5 7.5 11.8 0.29 11.5 4.0 2.9 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region WD40 PF00400.32 EST41478.1 - 2.4e-41 138.9 12.1 1e-07 32.5 0.1 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EST41478.1 - 8e-17 61.3 0.2 0.00037 20.7 0.0 4.8 2 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EST41478.1 - 1e-06 27.9 0.2 0.029 13.3 0.0 4.1 1 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EST41478.1 - 0.00044 19.7 0.0 0.023 14.1 0.0 2.8 2 1 0 2 2 2 1 WD40-like domain eIF2A PF08662.11 EST41478.1 - 0.0084 16.0 0.0 1.2 8.9 0.0 3.3 2 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EST41478.1 - 0.018 13.7 2.7 0.23 10.1 0.2 3.1 1 1 2 4 4 4 0 Nucleoporin Nup120/160 Myb_DNA-binding PF00249.31 EST41481.1 - 3.3e-10 40.0 0.2 0.00057 20.0 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST41481.1 - 4.5e-07 30.0 0.1 2e-06 27.9 0.1 1.9 1 1 1 2 2 2 2 Myb-like DNA-binding domain HTH_24 PF13412.6 EST41481.1 - 0.32 10.6 0.9 0.51 9.9 0.1 1.7 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_32 PF13565.6 EST41481.1 - 4.8 7.9 6.1 8.9 7.0 0.3 2.5 1 1 1 2 2 2 0 Homeodomain-like domain Ribosomal_L5e PF17144.4 EST41484.1 - 4.7e-73 244.6 1.6 5.3e-73 244.4 0.3 1.7 2 1 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 EST41484.1 - 3.9e-21 75.8 4.7 8.8e-21 74.7 4.7 1.6 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.22 EST41484.1 - 0.0019 18.6 0.0 0.0053 17.1 0.0 1.7 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Choline_transpo PF04515.12 EST41485.1 - 2.1e-47 161.9 43.3 2.1e-47 161.9 43.3 3.2 3 0 0 3 3 3 2 Plasma-membrane choline transporter H-kinase_dim PF02895.14 EST41486.1 - 0.42 11.0 2.6 0.5 10.8 0.1 2.4 3 0 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain DUF2633 PF11119.8 EST41487.1 - 0.13 12.2 0.2 0.36 10.8 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) DUF3917 PF13055.6 EST41487.1 - 2.4 8.7 7.6 0.48 10.9 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3917) UPF0730 PF15827.5 EST41488.1 - 0.085 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 UPF0730 unknown protein family DUF4164 PF13747.6 EST41489.1 - 0.0081 16.4 4.4 0.023 15.0 4.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4164) zf-C3HC4 PF00097.25 EST41490.1 - 2.2e-06 27.5 10.3 2.2e-06 27.5 10.3 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EST41490.1 - 6.3e-06 26.3 8.5 6.3e-06 26.3 8.5 2.6 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EST41490.1 - 9e-06 25.5 8.2 9e-06 25.5 8.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EST41490.1 - 0.00012 21.8 12.3 0.00012 21.8 12.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EST41490.1 - 0.00017 21.3 10.2 0.00017 21.3 10.2 2.6 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EST41490.1 - 0.0005 20.0 16.6 0.00064 19.7 6.3 3.2 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 EST41490.1 - 0.00076 19.8 10.6 0.00076 19.8 10.6 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 EST41490.1 - 0.0011 18.9 9.8 0.0011 18.9 9.8 2.2 2 0 0 2 2 2 1 zinc-RING finger domain U-box PF04564.15 EST41490.1 - 0.0012 19.0 0.2 0.0058 16.8 0.1 2.1 2 0 0 2 2 2 1 U-box domain Mac PF12464.8 EST41490.1 - 0.016 15.5 0.0 0.033 14.4 0.0 1.5 1 0 0 1 1 1 0 Maltose acetyltransferase zf-RING_6 PF14835.6 EST41490.1 - 0.14 12.0 5.9 0.064 13.1 3.1 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 EST41490.1 - 0.55 10.1 10.2 0.11 12.3 4.4 2.6 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 EST41490.1 - 0.78 9.9 12.9 0.27 11.4 7.6 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-UDP PF14569.6 EST41490.1 - 2.8 8.1 9.2 28 4.9 5.4 3.0 2 1 0 2 2 2 0 Zinc-binding RING-finger Zn_Tnp_IS91 PF14319.6 EST41490.1 - 3.6 7.7 8.9 3 7.9 3.8 2.9 2 1 0 2 2 2 0 Transposase zinc-binding domain Vps39_2 PF10367.9 EST41490.1 - 6.6 7.2 9.5 10 6.6 1.4 3.3 3 2 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 DUF4485 PF14846.6 EST41491.1 - 6.7e-05 22.8 0.5 0.0002 21.4 0.5 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4485) tRNA-synt_1g PF09334.11 EST41491.1 - 0.017 13.9 0.1 0.018 13.8 0.1 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (M) CH PF00307.31 EST41492.1 - 6.1e-07 29.6 0.1 1.8e-06 28.1 0.1 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain Flavodoxin_2 PF02525.17 EST41494.1 - 1.4e-20 73.8 0.0 1.7e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 EST41494.1 - 0.00079 19.2 0.0 0.00094 19.0 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Inhibitor_I36 PF03995.13 EST41494.1 - 0.094 12.7 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Peptidase inhibitor family I36 p25-alpha PF05517.12 EST41495.1 - 3.3e-13 50.1 0.3 3.8e-06 27.1 0.1 3.2 1 1 1 3 3 3 3 p25-alpha Plasmod_dom_1 PF09715.10 EST41496.1 - 0.17 11.9 0.2 0.85 9.7 0.2 2.2 1 0 0 1 1 1 0 Plasmodium protein of unknown function (Plasmod_dom_1) Cystatin PF00031.21 EST41498.1 - 7.5e-05 22.9 0.3 8.8e-05 22.7 0.3 1.2 1 0 0 1 1 1 1 Cystatin domain SQAPI PF16845.5 EST41498.1 - 0.0075 16.6 0.2 0.01 16.2 0.2 1.3 1 0 0 1 1 1 1 Aspartic acid proteinase inhibitor DUF296 PF03479.15 EST41498.1 - 0.14 12.5 0.0 0.16 12.4 0.0 1.1 1 0 0 1 1 1 0 Plants and Prokaryotes Conserved (PCC) domain CAMSAP_CKK PF08683.11 EST41499.1 - 2.4e-10 40.6 0.0 6.7e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated Met_10 PF02475.16 EST41500.1 - 2e-31 109.3 0.0 3.3e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 EST41500.1 - 2.1e-05 24.2 0.0 3.8e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain TRM PF02005.16 EST41500.1 - 0.0018 17.5 0.0 0.0028 16.9 0.0 1.3 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_25 PF13649.6 EST41500.1 - 0.018 15.7 0.0 0.044 14.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 EST41500.1 - 0.033 13.2 0.0 0.054 12.5 0.0 1.3 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Choline_transpo PF04515.12 EST41503.1 - 3.5e-46 157.9 40.2 3.5e-46 157.9 40.2 3.1 3 1 0 3 3 3 1 Plasma-membrane choline transporter UPF0242 PF06785.11 EST41503.1 - 3.7 7.6 7.7 0.68 10.0 0.7 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Fumble PF03630.14 EST41504.1 - 7.4e-09 35.2 0.0 9.1e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 Fumble MCM_OB PF17207.3 EST41504.1 - 0.14 12.0 0.1 0.56 10.1 0.0 1.8 1 1 1 2 2 2 0 MCM OB domain GMC_oxred_N PF00732.19 EST41506.1 - 0.0013 18.2 0.2 0.0021 17.5 0.2 1.2 1 0 0 1 1 1 1 GMC oxidoreductase BRCT PF00533.26 EST41506.1 - 0.097 13.1 0.1 0.24 11.8 0.1 1.7 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Utp12 PF04003.12 EST41509.1 - 0.064 13.6 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Dip2/Utp12 Family Fmp27_SW PF10305.9 EST41510.1 - 0.1 13.3 0.1 0.19 12.4 0.1 1.4 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Imm40 PF15569.6 EST41513.1 - 0.063 13.4 0.7 0.22 11.6 0.7 1.9 1 0 0 1 1 1 0 Immunity protein 40 Uteroglobin PF01099.17 EST41513.1 - 0.082 13.3 0.9 0.32 11.3 0.9 2.0 1 0 0 1 1 1 0 Uteroglobin family GreA_GreB_N PF03449.15 EST41513.1 - 3.3 7.9 7.8 2.2 8.5 0.1 3.0 3 0 0 3 3 3 0 Transcription elongation factor, N-terminal VSP PF03302.13 EST41514.1 - 1.9e-06 27.0 92.2 0.0017 17.3 40.8 2.8 1 1 1 2 2 2 2 Giardia variant-specific surface protein DUF4748 PF15932.5 EST41514.1 - 0.15 11.8 0.2 0.27 11.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) DUF945 PF06097.11 EST41514.1 - 0.44 9.6 1.9 0.54 9.3 1.9 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) Podoplanin PF05808.11 EST41514.1 - 0.59 10.2 7.2 0.91 9.6 6.8 1.7 1 1 0 1 1 1 0 Podoplanin DUF3042 PF11240.8 EST41514.1 - 0.73 9.9 1.9 1.6 8.8 1.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) VSP PF03302.13 EST41515.1 - 0.0019 17.1 81.7 0.085 11.7 41.5 2.2 1 1 1 2 2 2 2 Giardia variant-specific surface protein Podoplanin PF05808.11 EST41515.1 - 0.0071 16.5 0.1 0.0071 16.5 0.1 1.6 2 0 0 2 2 2 1 Podoplanin Furin-like_2 PF15913.5 EST41515.1 - 0.022 14.9 12.7 0.022 14.9 12.7 4.9 1 1 4 5 5 5 0 Furin-like repeat, cysteine-rich VSP PF03302.13 EST41517.1 - 4.3e-06 25.9 84.5 0.0025 16.7 38.7 2.4 1 1 1 2 2 2 2 Giardia variant-specific surface protein 3Beta_HSD PF01073.19 EST41517.1 - 0.05 12.6 0.5 0.072 12.1 0.5 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Podoplanin PF05808.11 EST41517.1 - 0.14 12.3 0.4 0.3 11.2 0.4 1.6 1 0 0 1 1 1 0 Podoplanin PARM PF17061.5 EST41517.1 - 0.62 10.2 3.0 1.3 9.1 3.0 1.5 1 0 0 1 1 1 0 PARM VSP PF03302.13 EST41518.1 - 5.9e-05 22.1 75.8 0.025 13.4 42.3 2.6 1 1 1 2 2 2 2 Giardia variant-specific surface protein Podoplanin PF05808.11 EST41518.1 - 1.1 9.4 6.8 1.8 8.7 6.8 1.5 1 1 0 1 1 1 0 Podoplanin VSP PF03302.13 EST41522.1 - 0.0007 18.6 0.0 0.0007 18.6 0.0 3.9 2 1 1 3 3 3 1 Giardia variant-specific surface protein DUF4366 PF14283.6 EST41522.1 - 0.1 12.6 0.1 0.1 12.6 0.1 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) LapA_dom PF06305.11 EST41522.1 - 0.29 11.0 0.4 0.42 10.5 0.4 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Podoplanin PF05808.11 EST41522.1 - 4.9 7.2 5.6 4.1 7.5 3.0 2.0 1 1 1 2 2 2 0 Podoplanin GP3 PF03076.14 EST41523.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Equine arteritis virus GP3 DUF4766 PF15973.5 EST41523.1 - 0.043 14.4 0.7 0.068 13.7 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4766) Methyltransf_13 PF08421.11 EST41524.1 - 0.046 14.0 0.1 0.097 12.9 0.1 1.4 1 0 0 1 1 1 0 Putative zinc binding domain VSP PF03302.13 EST41525.1 - 0.00045 19.2 0.2 0.00045 19.2 0.2 4.1 2 1 1 4 4 4 1 Giardia variant-specific surface protein Podoplanin PF05808.11 EST41525.1 - 0.04 14.0 1.4 0.096 12.8 1.4 1.6 1 0 0 1 1 1 0 Podoplanin Methyltransf_13 PF08421.11 EST41527.1 - 0.2 11.9 0.1 0.2 11.9 0.1 2.7 3 0 0 3 3 3 0 Putative zinc binding domain DUF4131 PF13567.6 EST41528.1 - 0.018 14.7 0.4 0.019 14.6 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) PrgI PF12666.7 EST41528.1 - 0.02 15.6 1.1 0.028 15.1 1.1 1.2 1 0 0 1 1 1 0 PrgI family protein DUF2244 PF10003.9 EST41528.1 - 0.037 13.7 0.4 0.044 13.5 0.4 1.0 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) OppC_N PF12911.7 EST41528.1 - 0.16 12.0 0.1 0.16 12.0 0.1 2.1 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF2207 PF09972.9 EST41528.1 - 0.25 10.1 4.2 0.28 9.9 4.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3951 PF13131.6 EST41528.1 - 9.3 6.5 10.5 14 6.0 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3951) Ribosomal_L4 PF00573.22 EST41529.1 - 1.4e-35 122.8 0.1 1.8e-35 122.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 EST41529.1 - 4.9e-08 32.9 0.4 4.7e-07 29.8 0.1 2.6 3 0 0 3 3 3 1 60S ribosomal protein L4 C-terminal domain NIF PF03031.18 EST41531.1 - 3.8e-46 156.7 0.9 4.9e-46 156.3 0.9 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase VMA21 PF09446.10 EST41532.1 - 3.5e-09 36.6 3.4 4.3e-09 36.3 3.4 1.2 1 0 0 1 1 1 1 VMA21-like domain Toxin_GhoT_OrtT PF10753.9 EST41532.1 - 0.036 14.3 1.1 0.07 13.4 0.1 1.8 2 0 0 2 2 2 0 Toxin GhoT_OrtT TNFR_16_TM PF18422.1 EST41532.1 - 1.2 9.2 4.7 0.19 11.7 0.8 1.7 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain Cpn60_TCP1 PF00118.24 EST41533.1 - 3.8e-135 451.3 3.9 4.3e-135 451.1 3.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SF-assemblin PF06705.11 EST41534.1 - 2.4e-06 27.1 34.3 0.0059 16.0 15.7 3.0 1 1 1 2 2 2 2 SF-assemblin/beta giardin CdvA PF18822.1 EST41534.1 - 0.0041 16.9 5.5 0.0041 16.9 5.5 4.0 3 1 0 4 4 4 1 CdvA-like coiled-coil domain Baculo_PEP_C PF04513.12 EST41534.1 - 0.26 11.3 18.3 1.2 9.1 6.1 3.4 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.8 EST41534.1 - 1.2 6.5 32.3 1.6 6.1 32.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3090 PF11290.8 EST41534.1 - 3.5 7.4 8.3 0.89 9.3 4.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3090) V-ATPase_G PF03179.15 EST41534.1 - 3.5 8.2 27.0 1.3 9.5 0.6 3.7 1 1 2 3 3 3 0 Vacuolar (H+)-ATPase G subunit Fib_alpha PF08702.10 EST41534.1 - 5.3 7.2 28.3 2.7 8.2 6.9 2.7 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF2767 PF10965.8 EST41534.1 - 6.7 6.8 11.0 0.82 9.7 0.4 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2767) FUSC PF04632.12 EST41534.1 - 8.4 4.8 7.2 3.8 5.9 4.1 1.7 1 1 1 2 2 2 0 Fusaric acid resistance protein family ApoLp-III PF07464.11 EST41534.1 - 8.7 6.4 26.6 6.4 6.9 7.7 2.9 1 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) SRF-TF PF00319.18 EST41536.1 - 2e-18 65.6 0.2 3.4e-18 64.8 0.2 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Diphthamide_syn PF01866.17 EST41537.1 - 0.025 14.0 0.6 0.032 13.7 0.6 1.2 1 0 0 1 1 1 0 Putative diphthamide synthesis protein HD_3 PF13023.6 EST41537.1 - 1.2 9.1 5.7 0.72 9.8 0.5 2.1 1 1 1 2 2 2 0 HD domain Ribosomal_L39 PF00832.20 EST41538.1 - 1.1e-08 34.5 10.4 1.4e-08 34.3 10.4 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Thioredoxin_16 PF18569.1 EST41540.1 - 0.3 11.2 0.1 0.3 11.2 0.1 2.2 2 1 0 2 2 2 0 Thioredoxin-like domain UBA PF00627.31 EST41540.1 - 0.44 10.5 0.1 0.44 10.5 0.1 2.2 2 0 0 2 2 2 0 UBA/TS-N domain Methyltrn_RNA_4 PF09936.9 EST41540.1 - 7.2 6.4 6.4 2.1 8.2 3.1 1.6 2 0 0 2 2 2 0 SAM-dependent RNA methyltransferase DUF4678 PF15727.5 EST41540.1 - 9 5.4 10.1 10 5.3 10.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4678) SeqA_N PF17206.3 EST41542.1 - 0.27 10.6 0.6 0.36 10.2 0.1 1.5 2 0 0 2 2 2 0 SeqA protein N-terminal domain DUF3624 PF12292.8 EST41545.1 - 0.022 15.2 0.7 0.022 15.2 0.7 3.0 4 1 0 4 4 4 0 Protein of unknown function (DUF3624) DUF4366 PF14283.6 EST41545.1 - 0.048 13.7 0.3 0.12 12.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Podoplanin PF05808.11 EST41545.1 - 0.08 13.0 0.4 0.08 13.0 0.4 1.8 2 0 0 2 2 2 0 Podoplanin VSP PF03302.13 EST41545.1 - 0.26 10.1 79.8 52 2.5 38.5 3.3 1 1 1 2 2 2 0 Giardia variant-specific surface protein VSP PF03302.13 EST41546.1 - 0.011 14.6 94.7 0.15 10.9 50.6 2.8 1 1 1 2 2 2 0 Giardia variant-specific surface protein DUF456 PF04306.13 EST41546.1 - 0.02 15.2 1.4 0.027 14.7 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Podoplanin PF05808.11 EST41546.1 - 0.36 10.9 7.6 0.61 10.2 6.2 1.8 2 1 0 2 2 2 0 Podoplanin VSP PF03302.13 EST41547.1 - 4.2e-06 25.9 84.2 1.8e-05 23.8 40.5 2.3 1 1 1 2 2 2 2 Giardia variant-specific surface protein Podoplanin PF05808.11 EST41547.1 - 0.00068 19.8 0.1 0.001 19.2 0.1 1.4 1 0 0 1 1 1 1 Podoplanin VSP PF03302.13 EST41550.1 - 7.5e-06 25.0 0.4 0.0047 15.8 0.0 2.0 2 0 0 2 2 2 2 Giardia variant-specific surface protein Podoplanin PF05808.11 EST41550.1 - 0.018 15.2 0.1 0.018 15.2 0.1 1.2 1 0 0 1 1 1 0 Podoplanin DUF4366 PF14283.6 EST41550.1 - 0.021 14.9 0.0 0.024 14.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF4748 PF15932.5 EST41550.1 - 0.026 14.3 0.1 0.039 13.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) LapA_dom PF06305.11 EST41550.1 - 0.06 13.2 0.5 0.078 12.8 0.5 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF3042 PF11240.8 EST41550.1 - 0.096 12.7 1.3 0.15 12.1 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) DUF485 PF04341.12 EST41550.1 - 0.16 11.9 0.0 0.2 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF485 DUF945 PF06097.11 EST41550.1 - 0.42 9.7 1.2 0.49 9.4 1.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) FeoB_associated PF12669.7 EST41550.1 - 8.6 6.8 8.5 3.2 8.2 1.2 2.2 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein DUF3142 PF11340.8 EST41553.1 - 0.13 12.1 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3142) CS PF04969.16 EST41557.1 - 6.4e-10 39.9 0.1 8.4e-10 39.5 0.1 1.2 1 0 0 1 1 1 1 CS domain Ribosomal_S13 PF00416.22 EST41560.1 - 7.4 7.0 11.4 4.8 7.6 0.5 3.0 2 2 1 3 3 3 0 Ribosomal protein S13/S18 Ribosomal_L44 PF00935.19 EST41561.1 - 2.6e-27 95.1 15.7 3.4e-27 94.7 15.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 DUF1126 PF06565.12 EST41562.1 - 8.1e-67 221.7 1.2 8e-27 93.1 0.2 3.3 3 0 0 3 3 3 3 DUF1126 PH-like domain RHH_7 PF16777.5 EST41562.1 - 0.039 14.4 0.0 2 8.9 0.0 2.6 2 0 0 2 2 2 0 Transcriptional regulator, RHH-like, CopG Myb_DNA-bind_7 PF15963.5 EST41563.1 - 0.00052 19.9 0.0 0.00073 19.4 0.0 1.3 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 EST41563.1 - 0.0015 18.7 0.1 0.0023 18.1 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EST41563.1 - 0.0088 16.2 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EST41563.1 - 0.012 15.8 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 VSP PF03302.13 EST41564.1 - 0.02 13.8 71.8 0.055 12.3 37.0 3.4 1 1 1 2 2 2 0 Giardia variant-specific surface protein Rax2 PF12768.7 EST41564.1 - 0.042 13.3 0.0 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Cor1 PF04803.12 EST41565.1 - 0.1 12.8 0.5 0.18 12.0 0.1 1.5 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region VirB7 PF17413.2 EST41565.1 - 0.15 11.4 0.1 0.3 10.4 0.1 1.5 1 0 0 1 1 1 0 Outer membrane lipoprotein virB7 VSP PF03302.13 EST41566.1 - 1.2e-06 27.7 64.8 4.4e-05 22.5 21.9 3.0 1 1 2 3 3 3 3 Giardia variant-specific surface protein VSP PF03302.13 EST41567.1 - 0.00025 20.0 43.6 0.00025 20.0 43.6 2.4 1 1 1 2 2 2 1 Giardia variant-specific surface protein VSP PF03302.13 EST41568.1 - 0.00036 19.5 0.1 0.00036 19.5 0.1 4.2 2 1 2 4 4 4 2 Giardia variant-specific surface protein Podoplanin PF05808.11 EST41568.1 - 0.026 14.6 0.4 0.064 13.4 0.4 1.6 1 0 0 1 1 1 0 Podoplanin Bacteriocin_IIc PF10439.9 EST41568.1 - 0.36 11.0 4.6 0.91 9.7 4.6 1.6 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DUF848 PF05852.11 EST41571.1 - 0.02 15.0 0.1 0.021 14.9 0.1 1.1 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) SHIPPO-rpt PF07004.12 EST41572.1 - 1.8e-11 44.3 11.1 0.13 13.2 0.1 7.3 8 0 0 8 8 8 4 Sperm-tail PG-rich repeat DUF5001 PF16392.5 EST41572.1 - 0.0098 15.8 0.2 18 5.3 0.0 3.8 4 1 0 4 4 4 1 Ig-like domain NAD_binding_5 PF07994.12 EST41572.1 - 0.099 12.0 0.7 0.53 9.6 0.1 2.4 3 1 1 4 4 4 0 Myo-inositol-1-phosphate synthase DUF5011 PF16403.5 EST41572.1 - 0.35 11.0 2.5 22 5.2 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF5011) HMMR_N PF15905.5 EST41572.1 - 4.1 6.8 11.8 0.15 11.5 1.9 2.9 3 1 1 4 4 4 0 Hyaluronan mediated motility receptor N-terminal GH97_C PF14509.6 EST41572.1 - 8.5 6.7 9.1 28 5.0 0.2 4.0 2 1 3 5 5 5 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation NADH_oxidored PF08040.11 EST41572.1 - 9.6 6.0 9.3 2e+02 1.8 0.1 4.7 5 0 0 5 5 5 0 MNLL subunit DUF5005 PF16396.5 EST41573.1 - 0.067 11.9 0.0 0.079 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5005) Myb_DNA-binding PF00249.31 EST41574.1 - 6.3e-12 45.5 0.2 2.8e-09 37.0 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST41574.1 - 1.9e-08 34.5 2.6 4.1e-07 30.2 0.3 2.3 2 1 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST41574.1 - 9.5e-08 31.8 4.0 3.5e-06 26.8 2.7 2.2 1 1 1 2 2 2 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EST41574.1 - 0.00035 20.7 4.4 0.0013 18.9 4.4 1.8 1 1 0 1 1 1 1 SANT/Myb-like domain of DAMP1 GCR1_C PF12550.8 EST41574.1 - 0.036 14.4 3.0 0.042 14.2 1.6 1.8 1 1 1 2 2 2 0 Transcriptional activator of glycolytic enzymes Pkinase PF00069.25 EST41575.1 - 1.4e-71 241.0 0.0 1.5e-71 240.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST41575.1 - 3.5e-34 118.3 0.0 4.4e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EST41575.1 - 0.00032 20.3 0.6 0.00071 19.2 0.6 1.4 1 1 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 EST41575.1 - 0.00059 19.2 0.0 0.0011 18.3 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EST41575.1 - 0.0012 18.8 0.2 0.0056 16.6 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EST41575.1 - 0.0026 17.2 1.1 0.0066 15.8 1.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EST41575.1 - 0.0053 15.8 0.6 0.075 12.0 0.6 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EST41575.1 - 0.1 11.3 1.1 0.25 10.1 0.4 1.4 1 1 1 2 2 2 0 Fungal protein kinase VSP PF03302.13 EST41578.1 - 0.0043 16.0 85.9 0.0081 15.1 47.3 2.3 1 1 1 2 2 2 2 Giardia variant-specific surface protein PARM PF17061.5 EST41578.1 - 2 8.5 3.4 3.5 7.7 3.4 1.3 1 0 0 1 1 1 0 PARM Podoplanin PF05808.11 EST41578.1 - 8.6 6.4 7.4 5.5 7.1 4.7 1.8 1 1 0 2 2 2 0 Podoplanin VSP PF03302.13 EST41579.1 - 3.5e-05 22.9 85.2 0.00021 20.3 38.7 2.5 1 1 1 2 2 2 2 Giardia variant-specific surface protein Podoplanin PF05808.11 EST41579.1 - 0.0041 17.3 0.5 0.009 16.1 0.5 1.6 1 0 0 1 1 1 1 Podoplanin DUF456 PF04306.13 EST41579.1 - 0.095 13.0 4.7 0.14 12.4 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) VSP PF03302.13 EST41580.1 - 1.8e-05 23.8 82.2 0.0054 15.6 33.6 2.3 1 1 1 2 2 2 2 Giardia variant-specific surface protein Podoplanin PF05808.11 EST41580.1 - 0.41 10.7 7.3 0.075 13.1 3.2 1.7 2 0 0 2 2 2 0 Podoplanin Podoplanin PF05808.11 EST41581.1 - 0.25 11.4 1.7 0.75 9.9 1.7 1.7 1 0 0 1 1 1 0 Podoplanin VSP PF03302.13 EST41581.1 - 5.5 5.7 65.8 0.049 12.5 26.0 3.7 1 1 1 2 2 2 0 Giardia variant-specific surface protein VSP PF03302.13 EST41582.1 - 0.00011 21.2 85.2 0.00049 19.1 38.2 2.3 1 1 1 2 2 2 2 Giardia variant-specific surface protein Podoplanin PF05808.11 EST41582.1 - 0.00036 20.7 0.1 0.00059 20.0 0.1 1.5 1 0 0 1 1 1 1 Podoplanin Rx_N PF18052.1 EST41584.1 - 1 9.6 8.6 7.1 7.0 0.2 3.6 3 1 0 3 3 3 0 Rx N-terminal domain Nas2_N PF18265.1 EST41586.1 - 0.01 15.7 0.0 0.016 15.1 0.0 1.4 1 1 0 1 1 1 0 Nas2 N_terminal domain zf-C2H2_2 PF12756.7 EST41587.1 - 0.00032 21.0 0.6 0.00085 19.6 0.1 1.9 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 EST41587.1 - 0.0021 18.3 0.8 0.0021 18.3 0.8 1.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding FAM76 PF16046.5 EST41587.1 - 0.05 13.0 10.9 0.076 12.4 10.9 1.3 1 0 0 1 1 1 0 FAM76 protein zf-C2H2 PF00096.26 EST41587.1 - 0.066 13.7 0.2 0.066 13.7 0.2 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EST41587.1 - 0.1 13.5 1.9 0.27 12.2 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Nif11 PF07862.11 EST41587.1 - 0.22 11.9 1.0 0.74 10.2 0.4 2.1 2 0 0 2 2 2 0 Nif11 domain DUF1178 PF06676.11 EST41587.1 - 6 7.2 7.0 0.92 9.9 2.0 2.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1178) CKS PF01111.19 EST41589.1 - 5e-33 113.2 2.1 5.6e-33 113.0 2.1 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DUF1965 PF09248.10 EST41589.1 - 0.019 14.7 0.6 0.075 12.8 0.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1965) Bromodomain PF00439.25 EST41590.1 - 6.3e-15 55.0 1.2 1e-14 54.4 0.1 1.9 2 0 0 2 2 2 1 Bromodomain Jnk-SapK_ap_N PF09744.9 EST41592.1 - 0.00041 20.6 2.3 0.00049 20.4 2.3 1.2 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Porin_3 PF01459.22 EST41592.1 - 0.019 14.5 0.3 0.022 14.2 0.3 1.1 1 0 0 1 1 1 0 Eukaryotic porin FlaC_arch PF05377.11 EST41592.1 - 0.037 14.4 0.7 0.066 13.6 0.7 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF641 PF04859.12 EST41592.1 - 0.095 13.0 4.0 0.11 12.8 3.9 1.3 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) TMF_DNA_bd PF12329.8 EST41592.1 - 0.097 12.7 3.0 0.18 11.8 3.0 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Ribosomal_L32e PF01655.18 EST41593.1 - 1.2e-35 122.2 0.0 1.4e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Ribosomal_60s PF00428.19 EST41594.1 - 3.1e-17 62.9 1.5 3.6e-17 62.7 1.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Sun2_CC2 PF18580.1 EST41594.1 - 0.11 12.8 0.3 5.8 7.2 0.1 2.3 2 0 0 2 2 2 0 SUN2 coiled coil domain 2 Myb_DNA-binding PF00249.31 EST41595.1 - 0.00025 21.2 0.0 0.001 19.2 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST41595.1 - 0.03 14.6 0.2 1.1 9.6 0.1 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST41595.1 - 0.041 13.8 0.0 0.053 13.4 0.0 1.2 1 0 0 1 1 1 0 Myb DNA-binding like KIAA1430 PF13879.6 EST41596.1 - 9.1e-16 58.5 0.7 9.1e-16 58.5 0.7 2.6 1 1 1 2 2 2 1 KIAA1430 homologue Ribosomal_S25 PF03297.15 EST41597.1 - 3.2e-17 62.6 2.0 3.7e-17 62.4 2.0 1.0 1 0 0 1 1 1 1 S25 ribosomal protein ParcG PF10274.9 EST41599.1 - 9.4e-73 244.2 0.0 1.1e-72 244.1 0.0 1.0 1 0 0 1 1 1 1 Parkin co-regulated protein Nrf1_DNA-bind PF10491.9 EST41600.1 - 0.45 10.2 3.1 0.45 10.2 0.7 1.9 2 0 0 2 2 2 0 NLS-binding and DNA-binding and dimerisation domains of Nrf1 DUF1387 PF07139.11 EST41600.1 - 0.63 9.7 6.6 0.8 9.4 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) BPL_N PF09825.9 EST41600.1 - 1.1 8.3 4.5 1.4 7.9 4.5 1.3 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Myb_DNA-binding PF00249.31 EST41602.1 - 4e-06 26.9 2.2 7.4e-06 26.1 2.2 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST41602.1 - 0.00094 19.4 4.1 0.0013 19.0 4.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain PilJ_C PF18223.1 EST41602.1 - 0.042 14.4 0.3 0.067 13.7 0.2 1.4 1 1 0 1 1 1 0 Pili PilJ C-terminal domain Myb_DNA-binding PF00249.31 EST41603.1 - 5.8e-11 42.4 0.6 0.00029 21.0 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST41603.1 - 1.2e-07 31.9 1.9 0.0039 17.4 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Use1 PF09753.9 EST41605.1 - 0.0056 16.4 0.3 0.0061 16.3 0.3 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 Aida_N PF08910.10 EST41605.1 - 0.0081 16.5 2.0 0.01 16.2 2.0 1.1 1 0 0 1 1 1 1 Aida N-terminus DUF2703 PF10865.8 EST41605.1 - 0.056 13.6 0.2 0.072 13.3 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2703) Rubis-subs-bind PF09273.11 EST41605.1 - 0.056 14.1 0.6 0.073 13.8 0.6 1.2 1 0 0 1 1 1 0 Rubisco LSMT substrate-binding DUF4492 PF14899.6 EST41606.1 - 0.13 12.2 1.1 0.29 11.1 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4492) COPI_assoc PF08507.10 EST41606.1 - 0.16 12.0 7.8 0.23 11.5 7.8 1.2 1 0 0 1 1 1 0 COPI associated protein HRG PF16954.5 EST41606.1 - 0.17 12.3 0.1 0.17 12.3 0.1 2.8 3 1 0 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene VSP PF03302.13 EST41607.1 - 1.1 8.0 92.6 0.42 9.4 37.4 4.0 1 1 2 3 3 3 0 Giardia variant-specific surface protein Podoplanin PF05808.11 EST41608.1 - 0.08 13.0 0.5 0.08 13.0 0.5 1.7 2 0 0 2 2 2 0 Podoplanin VSP PF03302.13 EST41608.1 - 0.3 9.9 69.0 0.031 13.2 26.3 4.1 1 1 2 3 3 3 0 Giardia variant-specific surface protein DUF4366 PF14283.6 EST41608.1 - 0.31 11.1 2.0 0.42 10.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Bacteriocin_IIc PF10439.9 EST41608.1 - 0.95 9.6 6.0 1.7 8.8 6.0 1.3 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide VSP PF03302.13 EST41610.1 - 0.0014 17.5 0.0 0.0014 17.5 0.0 3.3 2 1 1 3 3 3 1 Giardia variant-specific surface protein Podoplanin PF05808.11 EST41610.1 - 0.01 16.0 0.1 0.024 14.7 0.0 1.6 2 0 0 2 2 2 0 Podoplanin DUF4366 PF14283.6 EST41610.1 - 0.017 15.1 0.0 0.033 14.2 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Metallothi_Euk2 PF12809.7 EST41611.1 - 0.15 12.4 13.7 1.6 9.1 13.4 2.1 1 1 0 1 1 1 0 Eukaryotic metallothionein Dickkopf_N PF04706.12 EST41611.1 - 0.45 11.0 14.7 0.21 12.1 2.1 2.2 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region Podoplanin PF05808.11 EST41615.1 - 0.0016 18.6 0.2 0.0034 17.5 0.1 1.8 2 0 0 2 2 2 1 Podoplanin VSP PF03302.13 EST41615.1 - 0.002 17.0 95.9 0.048 12.5 57.0 3.2 1 1 1 2 2 2 2 Giardia variant-specific surface protein VSP PF03302.13 EST41616.1 - 6.5e-07 28.5 83.0 0.00024 20.1 42.0 2.3 1 1 1 2 2 2 2 Giardia variant-specific surface protein Podoplanin PF05808.11 EST41616.1 - 0.0031 17.6 0.2 0.0058 16.7 0.2 1.5 1 0 0 1 1 1 1 Podoplanin Furin-like_2 PF15913.5 EST41616.1 - 0.018 15.2 12.7 0.018 15.2 12.7 4.9 1 1 4 5 5 5 0 Furin-like repeat, cysteine-rich VSP PF03302.13 EST41617.1 - 2.2e-09 36.7 14.3 2.2e-09 36.7 14.3 2.0 1 1 1 2 2 2 1 Giardia variant-specific surface protein Podoplanin PF05808.11 EST41617.1 - 0.0092 16.1 0.0 0.024 14.7 0.0 1.6 2 0 0 2 2 2 1 Podoplanin DUF4366 PF14283.6 EST41617.1 - 0.024 14.7 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF3624 PF12292.8 EST41617.1 - 0.068 13.6 1.9 0.068 13.6 1.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3624) Bacteriocin_IIc PF10439.9 EST41617.1 - 1.9 8.7 8.9 0.55 10.4 5.3 1.9 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide GBP_PSP PF02425.15 EST41617.1 - 2.5 7.8 8.8 8.4 6.1 0.5 3.3 3 0 0 3 3 3 0 Paralytic/GBP/PSP peptide Dickkopf_N PF04706.12 EST41618.1 - 0.69 10.4 14.3 1.1 9.8 8.8 2.2 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region Podoplanin PF05808.11 EST41619.1 - 0.00028 21.0 3.5 0.0006 20.0 3.6 1.6 1 1 0 1 1 1 1 Podoplanin Bacteriocin_IIc PF10439.9 EST41619.1 - 0.2 11.8 4.7 0.1 12.8 2.4 1.7 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide PsbX PF06596.11 EST41619.1 - 0.69 10.0 3.4 1.2 9.2 3.4 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) VSP PF03302.13 EST41622.1 - 0.003 16.5 0.1 0.003 16.5 0.1 3.8 2 1 1 3 3 3 1 Giardia variant-specific surface protein DUF4366 PF14283.6 EST41622.1 - 0.021 14.9 0.0 0.056 13.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF3624 PF12292.8 EST41622.1 - 0.021 15.2 0.5 0.021 15.2 0.5 3.0 4 1 1 5 5 5 0 Protein of unknown function (DUF3624) Podoplanin PF05808.11 EST41622.1 - 0.024 14.8 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 Podoplanin FAP PF07174.11 EST41622.1 - 2 7.8 25.0 3.3 7.1 25.0 1.4 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) TMEM52 PF14979.6 EST41624.1 - 0.0033 17.4 1.4 0.0041 17.1 1.4 1.3 1 1 0 1 1 1 1 Transmembrane 52 MLANA PF14991.6 EST41624.1 - 0.0043 17.3 0.0 0.0061 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein melan-A Ribosomal_L13e PF01294.18 EST41625.1 - 6.7e-45 153.1 4.5 9.1e-45 152.7 4.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Sigma_reg_N PF13800.6 EST41626.1 - 0.87 9.9 4.6 1.1 9.6 4.6 1.4 1 1 0 1 1 1 0 Sigma factor regulator N-terminal Bunya_G2 PF03563.13 EST41626.1 - 3 7.0 9.2 2.4 7.4 7.8 1.5 1 1 1 2 2 2 0 Bunyavirus glycoprotein G2 FeoB_associated PF12669.7 EST41626.1 - 3 8.3 5.7 9.1 6.8 5.7 1.8 1 1 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Comm PF15957.5 EST41628.1 - 0.0039 17.5 0.1 0.0043 17.4 0.1 1.1 1 0 0 1 1 1 1 Commissureless Ycf70 PF17382.2 EST41628.1 - 0.012 16.0 0.1 0.014 15.8 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized Ycf70-like Shisa PF13908.6 EST41628.1 - 0.014 15.7 0.1 0.016 15.5 0.1 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator TssO PF17561.2 EST41628.1 - 0.035 14.2 1.8 0.039 14.0 1.8 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssO SafA PF17073.5 EST41628.1 - 0.041 13.8 0.7 0.055 13.4 0.7 1.3 1 0 0 1 1 1 0 Two-component-system connector protein WBP-1 PF11669.8 EST41628.1 - 0.085 13.5 0.2 0.1 13.2 0.2 1.1 1 0 0 1 1 1 0 WW domain-binding protein 1 TMEM132D_C PF15706.5 EST41628.1 - 0.093 12.5 2.0 0.12 12.2 2.0 1.3 1 1 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Vpu PF00558.19 EST41628.1 - 0.16 11.8 3.6 0.21 11.4 3.4 1.3 1 1 0 1 1 1 0 Vpu protein ASFV_J13L PF05568.11 EST41628.1 - 0.16 11.7 0.4 0.17 11.6 0.4 1.1 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF3139 PF11337.8 EST41628.1 - 0.18 12.5 1.6 0.22 12.2 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) Sigma_reg_N PF13800.6 EST41628.1 - 0.41 11.0 7.5 6.1 7.2 7.5 2.0 1 1 0 1 1 1 0 Sigma factor regulator N-terminal TMEM154 PF15102.6 EST41628.1 - 0.7 9.8 4.0 0.94 9.4 4.0 1.3 1 1 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 EST41628.1 - 0.78 10.7 3.4 1.1 10.2 3.4 1.4 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Synaptobrevin PF00957.21 EST41628.1 - 0.96 9.3 6.5 0.69 9.7 0.3 2.1 2 0 0 2 2 2 0 Synaptobrevin DUF1514 PF07438.11 EST41628.1 - 2.6 8.0 6.1 6.1 6.8 5.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1514) SIT PF15330.6 EST41628.1 - 3.9 7.9 7.6 10 6.6 7.6 1.8 1 1 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Cpn60_TCP1 PF00118.24 EST41630.1 - 9e-127 423.7 13.2 1e-126 423.5 13.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rad60-SLD PF11976.8 EST41630.1 - 0.036 13.9 1.0 2.7 7.9 0.0 3.5 2 1 1 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like Hydant_A_N PF05378.13 EST41632.1 - 0.26 11.0 5.4 0.061 13.0 1.2 2.0 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase N-terminal region FHA PF00498.26 EST41636.1 - 1.1e-17 64.1 0.0 2.6e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EST41636.1 - 1.1e-10 41.7 0.0 3.6e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-ribbon_3 PF13248.6 EST41636.1 - 0.17 11.4 0.1 0.33 10.4 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Ribosomal_L37e PF01907.19 EST41637.1 - 1.2e-22 79.8 7.6 1.8e-22 79.2 7.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e HypA PF01155.19 EST41637.1 - 0.083 12.9 0.8 0.11 12.5 0.8 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ENTH PF01417.20 EST41638.1 - 9.3e-23 80.6 0.1 1.5e-22 80.0 0.1 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 EST41638.1 - 0.0087 15.1 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 ANTH domain Mid2 PF04478.12 EST41639.1 - 0.69 9.7 3.6 0.96 9.3 2.7 1.6 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor VSP PF03302.13 EST41640.1 - 0.0028 16.6 0.0 0.0028 16.6 0.0 4.0 2 1 1 3 3 3 2 Giardia variant-specific surface protein Podoplanin PF05808.11 EST41640.1 - 0.02 15.0 0.0 0.047 13.8 0.0 1.5 1 0 0 1 1 1 0 Podoplanin DUF4366 PF14283.6 EST41640.1 - 0.022 14.8 0.0 0.076 13.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Rdx PF10262.9 EST41643.1 - 4e-09 36.5 0.0 4.4e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Rdx family TRM13 PF05206.14 EST41646.1 - 2.1e-28 99.6 2.1 2.6e-20 73.1 0.9 2.2 1 1 1 2 2 2 2 Methyltransferase TRM13 Methyltransf_32 PF13679.6 EST41646.1 - 0.00017 21.6 0.4 0.0003 20.8 0.4 1.3 1 0 0 1 1 1 1 Methyltransferase domain zf-U11-48K PF05253.12 EST41646.1 - 0.00022 21.0 1.4 0.00049 19.9 1.4 1.6 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger DUF807 PF05660.11 EST41647.1 - 0.036 14.0 0.0 0.081 12.9 0.0 1.5 1 0 0 1 1 1 0 Coxiella burnetii protein of unknown function (DUF807) RRM_1 PF00076.22 EST41648.1 - 0.00069 19.4 1.4 0.71 9.7 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF883 PF05957.13 EST41649.1 - 0.27 11.8 4.0 8.3 7.1 0.4 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF244 PF03112.14 EST41649.1 - 0.59 10.0 10.3 0.034 14.0 2.8 2.3 1 1 1 2 2 2 0 Uncharacterized protein family (ORF7) DUF GlutR_dimer PF00745.20 EST41649.1 - 0.73 10.3 5.6 3.3 8.2 0.3 3.1 3 1 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain Fzo_mitofusin PF04799.13 EST41649.1 - 1.1 8.8 23.6 2.7 7.5 3.4 4.1 3 1 1 4 4 4 0 fzo-like conserved region DUF99 PF01949.16 EST41649.1 - 2.2 7.6 3.6 7 6.0 0.5 2.7 2 1 1 3 3 3 0 Protein of unknown function DUF99 LCAT PF02450.15 EST41650.1 - 1.4e-18 67.3 0.5 3.5e-18 66.0 0.0 1.9 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase PGAP1 PF07819.13 EST41650.1 - 1.9e-06 27.8 0.1 2.2e-05 24.3 0.0 2.7 2 1 0 2 2 2 1 PGAP1-like protein Lipase_2 PF01674.18 EST41650.1 - 0.00019 21.0 0.0 0.00046 19.8 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 2) DUF676 PF05057.14 EST41650.1 - 0.0006 19.4 0.1 0.0013 18.2 0.1 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF900 PF05990.12 EST41650.1 - 0.0045 16.5 0.0 0.0085 15.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.8 EST41650.1 - 0.0066 15.7 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF915 PF06028.11 EST41650.1 - 0.024 14.0 0.2 0.12 11.7 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) PseudoU_synth_2 PF00849.22 EST41652.1 - 3.3e-18 66.3 0.1 6.5e-18 65.3 0.1 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase InvH PF04741.12 EST41652.1 - 0.01 15.8 0.4 0.02 14.8 0.1 1.6 2 0 0 2 2 2 0 InvH outer membrane lipoprotein Zap1_zf2 PF18217.1 EST41652.1 - 0.14 12.2 0.7 0.33 11.0 0.7 1.6 1 0 0 1 1 1 0 Zap1 zinc finger 2 DEAD PF00270.29 EST41653.1 - 1.9e-40 138.5 0.2 6.8e-40 136.7 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EST41653.1 - 1.4e-24 86.6 0.0 6.2e-24 84.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EST41653.1 - 2.2e-15 56.6 0.2 4.6e-15 55.6 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ERCC3_RAD25_C PF16203.5 EST41653.1 - 8.1e-05 21.9 0.9 0.0014 17.8 0.0 2.2 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Tctex-1 PF03645.13 EST41654.1 - 6.1e-15 55.3 0.4 7.1e-15 55.1 0.4 1.1 1 0 0 1 1 1 1 Tctex-1 family Methyltransf_15 PF09445.10 EST41655.1 - 3.3e-14 52.8 0.3 3.3e-14 52.8 0.3 1.7 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase RrnaAD PF00398.20 EST41655.1 - 6.4e-07 28.7 0.0 9.1e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.14 EST41655.1 - 1e-05 25.2 0.0 1.7e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 EST41655.1 - 0.00054 19.7 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 EST41655.1 - 0.002 18.8 0.0 0.0039 17.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 EST41655.1 - 0.046 13.4 0.0 0.099 12.3 0.0 1.5 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F Ecm33 PF12454.8 EST41655.1 - 0.053 13.7 0.0 1.7 8.9 0.0 2.5 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein RSN1_7TM PF02714.15 EST41657.1 - 1.8e-23 83.3 26.6 1.8e-23 83.3 26.6 2.8 4 1 0 4 4 4 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EST41657.1 - 6.1e-10 39.1 9.4 6.1e-10 39.1 9.4 3.9 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport Lipase_GDSL_2 PF13472.6 EST41658.1 - 9.6e-09 35.9 0.0 7.7e-08 32.9 0.0 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EST41658.1 - 1.4e-07 31.7 0.2 1.1e-05 25.5 0.2 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Dcc1 PF09724.9 EST41659.1 - 2.8e-06 26.9 1.1 0.016 14.6 0.1 2.4 2 1 0 2 2 2 2 Sister chromatid cohesion protein Dcc1 DUF4751 PF15942.5 EST41659.1 - 0.0087 16.0 2.3 0.059 13.3 0.1 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4751) Imm39 PF15568.6 EST41659.1 - 0.14 12.3 0.1 0.28 11.3 0.1 1.6 1 1 0 1 1 1 0 Immunity protein 39 DUF1676 PF07898.13 EST41660.1 - 0.062 13.3 3.4 0.28 11.2 3.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1676) Sec20 PF03908.13 EST41660.1 - 0.17 11.8 11.1 0.22 11.5 0.4 2.5 2 0 0 2 2 2 0 Sec20 ETRAMP PF09716.10 EST41660.1 - 4.5 7.4 9.1 0.89 9.7 5.3 1.9 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Fes1 PF08609.10 EST41662.1 - 0.018 15.9 2.0 0.041 14.8 2.0 1.6 1 0 0 1 1 1 0 Nucleotide exchange factor Fes1 Vasculin PF15337.6 EST41662.1 - 0.05 14.4 0.7 0.23 12.3 0.7 2.1 1 0 0 1 1 1 0 Vascular protein family Vasculin-like 1 DbpA PF03880.15 EST41664.1 - 0.4 10.7 2.9 6.1 6.9 0.3 3.1 2 0 0 2 2 2 0 DbpA RNA binding domain Ribosomal_L31e PF01198.19 EST41666.1 - 1e-12 48.1 0.8 1.3e-12 47.8 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Acyltransferase PF01553.21 EST41667.1 - 1.1e-17 63.9 0.0 1.8e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Ion_trans_2 PF07885.16 EST41669.1 - 5e-13 48.8 7.0 5e-13 48.8 7.0 3.1 3 1 0 3 3 3 1 Ion channel DUF4806 PF16064.5 EST41669.1 - 0.24 11.7 1.8 1.1 9.6 0.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4806) UQ_con PF00179.26 EST41670.1 - 2.5e-14 53.1 0.0 3.3e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf_C2H2_10 PF18414.1 EST41670.1 - 1.9 8.1 4.0 1 9.0 1.1 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger FTO_CTD PF12934.7 EST41671.1 - 0.0045 16.8 0.1 0.0069 16.2 0.1 1.3 1 0 0 1 1 1 1 FTO C-terminal domain ABC_tran_CTD PF16326.5 EST41671.1 - 0.068 13.4 1.3 1.7 8.9 0.6 2.5 2 1 0 2 2 2 0 ABC transporter C-terminal domain PSK_trans_fac PF07704.11 EST41672.1 - 0.0082 16.9 0.2 0.0082 16.9 0.2 5.1 2 2 3 6 6 6 1 Rv0623-like transcription factor Vps4_C PF09336.10 EST41672.1 - 0.033 14.2 0.1 0.18 11.8 0.1 2.4 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain Ank_2 PF12796.7 EST41673.1 - 8.1e-17 61.6 1.0 1.6e-14 54.2 0.5 2.7 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EST41673.1 - 2.6e-15 56.6 1.5 2e-11 44.2 0.3 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EST41673.1 - 2.2e-10 40.5 0.5 0.00049 20.4 0.0 2.9 2 1 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EST41673.1 - 3.1e-10 39.4 0.2 0.0052 17.2 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EST41673.1 - 9.5e-10 38.5 0.5 0.00052 20.3 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) TMEM71 PF15121.6 EST41673.1 - 0.092 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 TMEM71 protein family STAT6_C PF14596.6 EST41674.1 - 0.04 13.9 0.9 5.8 6.9 0.0 2.3 2 0 0 2 2 2 0 STAT6 C-terminal Pkinase PF00069.25 EST41676.1 - 8e-33 113.9 3.3 2.3e-18 66.5 0.0 3.3 2 1 0 2 2 2 2 Protein kinase domain Ank_2 PF12796.7 EST41677.1 - 0.1 13.2 0.3 0.51 10.9 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) SHS2_FTSA PF02491.20 EST41677.1 - 0.13 12.7 0.3 0.55 10.7 0.3 2.1 1 0 0 1 1 1 0 SHS2 domain inserted in FTSA Y_phosphatase PF00102.27 EST41681.1 - 5.1e-27 95.0 0.1 3e-26 92.4 0.1 1.9 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 EST41681.1 - 5.5e-05 23.0 0.5 0.00012 21.9 0.5 1.6 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EST41681.1 - 0.002 18.3 0.0 0.0031 17.7 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate PsaF PF17550.2 EST41681.1 - 0.0036 16.8 0.0 0.0067 15.9 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function YabA PF06156.13 EST41683.1 - 0.66 10.7 11.0 0.21 12.3 4.8 2.9 2 1 1 3 3 3 0 Initiation control protein YabA MRP-S26 PF14943.6 EST41683.1 - 1.5 8.7 12.4 3.6 7.5 11.5 1.9 1 1 1 2 2 2 0 Mitochondrial ribosome subunit S26 LMBR1 PF04791.16 EST41683.1 - 2.8 6.8 3.8 4 6.2 3.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Spc24 PF08286.11 EST41683.1 - 4.6 7.5 13.7 4.7 7.5 4.4 3.5 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 Cnn_1N PF07989.11 EST41683.1 - 5.9 7.1 17.4 3.5 7.9 6.7 4.1 2 2 2 4 4 4 0 Centrosomin N-terminal motif 1 Ly49 PF08391.10 EST41683.1 - 9.3 6.6 10.5 0.67 10.3 0.3 2.5 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region LLC1 PF14945.6 EST41685.1 - 0.053 14.1 0.1 0.12 12.9 0.1 1.6 1 1 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein SHIPPO-rpt PF07004.12 EST41685.1 - 0.34 11.9 28.9 0.46 11.5 0.9 5.3 6 0 0 6 6 6 0 Sperm-tail PG-rich repeat PMR5N PF14416.6 EST41687.1 - 0.062 13.6 0.1 0.14 12.5 0.1 1.5 1 0 0 1 1 1 0 PMR5 N terminal Domain Ank_2 PF12796.7 EST41688.1 - 2.4e-16 60.1 0.9 6.3e-14 52.3 0.5 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EST41688.1 - 6.2e-12 45.8 0.6 1.8e-11 44.3 0.3 2.0 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EST41688.1 - 1.7e-10 40.9 0.5 0.00044 20.6 0.0 2.9 2 1 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EST41688.1 - 2.4e-10 39.7 0.2 0.0047 17.3 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EST41688.1 - 6.2e-10 39.1 0.5 0.00045 20.5 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) TMEM71 PF15121.6 EST41688.1 - 0.081 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 TMEM71 protein family Histone PF00125.24 EST41689.1 - 4.5e-28 98.2 1.0 5.7e-28 97.9 1.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EST41689.1 - 2.6e-05 24.3 0.1 5.8e-05 23.2 0.0 1.6 1 1 1 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 EST41689.1 - 0.00027 21.1 1.7 0.00076 19.7 0.8 2.3 2 1 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 EST41689.1 - 0.006 16.6 0.0 0.036 14.1 0.1 1.9 2 0 0 2 2 2 1 Bromodomain associated CENP-S PF15630.6 EST41689.1 - 0.062 13.7 0.1 0.12 12.8 0.1 1.6 1 1 0 1 1 1 0 CENP-S protein Exo_endo_phos PF03372.23 EST41690.1 - 0.012 15.1 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family zf-CHY PF05495.12 EST41691.1 - 5.3e-15 55.7 16.4 5.3e-15 55.7 16.4 4.5 1 1 3 4 4 4 1 CHY zinc finger zinc_ribbon_6 PF14599.6 EST41691.1 - 7.5e-10 38.7 1.9 7.5e-10 38.7 1.9 4.2 4 0 0 4 4 4 1 Zinc-ribbon zf-RING_2 PF13639.6 EST41691.1 - 1.3e-08 35.0 8.6 1.3e-08 35.0 8.6 6.1 5 1 0 5 5 5 1 Ring finger domain zf-C3HC4_2 PF13923.6 EST41691.1 - 5.3e-06 26.2 11.0 5.3e-06 26.2 11.0 4.9 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EST41691.1 - 0.0012 18.6 7.1 0.0012 18.6 7.1 3.3 3 0 0 3 3 3 1 RING-like zinc finger DJ-1_PfpI PF01965.24 EST41693.1 - 0.003 17.4 0.0 0.0038 17.1 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DUF3137 PF11335.8 EST41693.1 - 0.046 13.7 1.2 0.082 12.9 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3137) Pkinase PF00069.25 EST41695.1 - 4.3e-57 193.5 1.0 5.8e-57 193.1 0.1 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST41695.1 - 6.1e-39 133.9 0.2 1.7e-38 132.4 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase FTA2 PF13095.6 EST41695.1 - 0.00096 18.8 0.0 1 9.0 0.0 2.9 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EST41695.1 - 0.016 14.0 2.2 0.019 13.7 0.1 1.9 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 EST41695.1 - 0.047 13.0 0.0 0.099 12.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinesin PF00225.23 EST41696.1 - 3.9e-68 229.8 8.7 3.9e-68 229.8 8.7 2.9 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 EST41696.1 - 3e-16 59.7 0.7 3e-16 59.7 0.7 3.5 3 1 0 3 3 3 1 Microtubule binding TA0956 PF11513.8 EST41696.1 - 1.8 8.8 9.1 10 6.4 0.1 4.3 4 2 1 5 5 5 0 Thermoplasma acidophilum protein TA0956 Peptidase_C1 PF00112.23 EST41697.1 - 1.5e-05 25.2 2.4 2.3e-05 24.6 0.1 2.4 3 0 0 3 3 3 1 Papain family cysteine protease Exo_endo_phos PF03372.23 EST41698.1 - 3.7e-07 29.9 0.1 1.4e-06 28.0 0.1 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MpPF1 PF07668.11 EST41698.1 - 0.045 13.0 1.1 0.09 12.0 0.3 1.8 2 0 0 2 2 2 0 M penetrans paralogue family 1 Lactamase_B PF00753.27 EST41699.1 - 2e-23 83.4 0.0 2.5e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EST41699.1 - 0.00022 20.8 0.0 0.00031 20.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PAPA-1 PF04795.12 EST41700.1 - 0.016 16.0 3.9 0.027 15.2 3.9 1.4 1 0 0 1 1 1 0 PAPA-1-like conserved region POLO_box PF00659.18 EST41701.1 - 0.13 12.5 1.5 0.76 10.0 0.3 2.7 2 0 0 2 2 2 0 POLO box duplicated region DEAD_2 PF06733.15 EST41702.1 - 0.02 14.5 0.2 0.042 13.5 0.2 1.6 1 1 0 1 1 1 0 DEAD_2 zf-CHY PF05495.12 EST41703.1 - 5e-15 55.7 16.4 5e-15 55.7 16.4 5.3 2 1 4 6 6 6 1 CHY zinc finger zf-RING_2 PF13639.6 EST41703.1 - 2.1e-08 34.4 4.5 2.1e-08 34.4 4.5 5.3 3 1 2 5 5 5 1 Ring finger domain zf-C3HC4_3 PF13920.6 EST41703.1 - 5.8e-06 26.1 4.4 5.8e-06 26.1 4.4 5.5 3 1 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EST41703.1 - 9.8e-06 25.4 6.2 9.8e-06 25.4 6.2 5.8 6 1 0 6 6 6 1 zinc-RING finger domain AAA_14 PF13173.6 EST41704.1 - 3.4e-05 23.9 1.1 6e-05 23.1 0.2 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EST41704.1 - 0.048 14.0 0.0 0.063 13.7 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain DNA_pol3_delta2 PF13177.6 EST41704.1 - 0.65 9.8 7.3 0.21 11.3 1.3 2.3 2 1 0 3 3 3 0 DNA polymerase III, delta subunit Stn1_C PF12659.7 EST41706.1 - 0.00012 22.0 1.1 0.00012 22.0 1.1 2.3 2 1 0 2 2 2 1 Telomere capping C-terminal wHTH DUF2340 PF10209.9 EST41707.1 - 5.2e-13 49.5 0.1 6.3e-13 49.2 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Sec23_trunk PF04811.15 EST41709.1 - 3.1e-07 30.2 0.1 7e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.15 EST41709.1 - 2.3e-05 24.3 4.3 7.1e-05 22.8 4.3 1.9 1 1 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 EST41709.1 - 0.00047 20.8 0.2 0.0021 18.7 0.1 2.2 1 1 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EST41709.1 - 0.0033 17.2 0.0 0.011 15.5 0.0 2.0 1 0 0 1 1 1 1 Sec23/Sec24 helical domain DUF3802 PF12290.8 EST41709.1 - 0.031 14.8 0.2 0.59 10.7 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3802) Luteo_coat PF00894.18 EST41709.1 - 0.032 14.1 0.1 0.49 10.3 0.0 2.6 2 0 0 2 2 2 0 Luteovirus coat protein MTS PF05175.14 EST41710.1 - 0.027 14.0 0.2 0.062 12.9 0.2 1.6 1 0 0 1 1 1 0 Methyltransferase small domain DMSP_lyase PF16867.5 EST41710.1 - 0.063 12.9 0.8 0.13 11.9 0.8 1.5 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase Lactamase_B PF00753.27 EST41711.1 - 1.1e-09 38.6 0.0 1.6e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EST41711.1 - 5.5e-07 29.3 0.0 1.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 EST41711.1 - 0.0072 15.8 0.1 0.014 14.8 0.1 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain UPF0122 PF04297.14 EST41712.1 - 4.5 7.6 11.7 0.38 11.0 5.0 2.4 2 1 1 3 3 3 0 Putative helix-turn-helix protein, YlxM / p13 like DUF5071 PF16804.5 EST41714.1 - 0.1 12.9 1.2 0.55 10.5 0.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5071) DUF503 PF04456.12 EST41715.1 - 0.017 14.9 0.0 0.036 13.9 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF503) Baculo_PEP_C PF04513.12 EST41715.1 - 0.11 12.5 3.5 0.2 11.7 0.2 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MSC PF09402.10 EST41716.1 - 9.7e-05 22.0 1.1 9.7e-05 22.0 1.1 2.5 1 1 1 2 2 2 1 Man1-Src1p-C-terminal domain HALZ PF02183.18 EST41717.1 - 0.0016 18.6 3.7 0.0016 18.6 3.7 7.3 8 1 0 8 8 8 2 Homeobox associated leucine zipper DNA_pack_N PF02500.15 EST41718.1 - 0.13 12.1 2.0 0.092 12.6 0.5 1.5 2 0 0 2 2 2 0 Probable DNA packing protein, N-terminus Peptidase_S28 PF05577.12 EST41719.1 - 1.4e-72 244.9 2.2 2.4e-72 244.1 2.2 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 EST41719.1 - 3.8e-06 26.8 0.0 6.9e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EST41719.1 - 0.0039 16.5 0.0 0.0063 15.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EST41719.1 - 0.011 15.3 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Mob1_phocein PF03637.17 EST41720.1 - 2.7e-44 151.2 3.6 4.2e-44 150.5 3.6 1.3 1 0 0 1 1 1 1 Mob1/phocein family RNA_pol_Rpb6 PF01192.22 EST41721.1 - 7.1e-14 51.5 0.0 9.3e-14 51.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb6 DUF3342 PF11822.8 EST41722.1 - 3.5e-05 23.9 0.4 3.5e-05 23.9 0.4 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF3342) CotJB PF12652.7 EST41722.1 - 2.8 8.2 4.9 12 6.2 0.0 3.9 2 1 1 3 3 3 0 CotJB protein Mak16 PF04874.14 EST41722.1 - 5.2 7.7 6.3 1.1 9.9 0.4 2.6 2 1 0 2 2 2 0 Mak16 protein C-terminal region DUF3850 PF12961.7 EST41723.1 - 0.02 14.9 0.2 0.052 13.6 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3850) Ank_2 PF12796.7 EST41724.1 - 1.2e-51 173.2 17.9 3.8e-13 49.8 0.1 8.4 1 1 4 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EST41724.1 - 1.9e-24 85.7 9.5 0.0041 17.7 0.0 10.4 10 2 1 11 11 11 6 Ankyrin repeats (many copies) Ank PF00023.30 EST41724.1 - 4.7e-24 83.7 14.2 0.00084 19.7 0.0 12.4 11 4 4 15 15 15 8 Ankyrin repeat Ank_3 PF13606.6 EST41724.1 - 7.5e-24 81.2 13.6 0.024 15.1 0.0 13.5 12 3 3 15 15 15 5 Ankyrin repeat Ank_5 PF13857.6 EST41724.1 - 1.4e-18 66.7 9.0 0.13 12.6 0.1 11.3 8 3 5 13 13 13 7 Ankyrin repeats (many copies) DUF3447 PF11929.8 EST41724.1 - 0.0027 17.6 20.2 0.087 12.8 1.0 5.4 1 1 5 6 6 6 3 Domain of unknown function (DUF3447) PsbW PF07123.12 EST41724.1 - 0.1 12.6 0.5 0.2 11.7 0.5 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) Peptidase_C1 PF00112.23 EST41725.1 - 3.9e-58 197.1 3.6 3.9e-58 197.1 3.6 1.7 2 0 0 2 2 2 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EST41725.1 - 0.00075 18.4 0.7 0.88 8.3 0.3 2.5 2 0 0 2 2 2 2 Peptidase C1-like family V-set_2 PF15910.5 EST41725.1 - 0.0095 16.0 0.2 0.033 14.3 0.2 1.9 1 0 0 1 1 1 1 ICOS V-set domain Myb_DNA-binding PF00249.31 EST41726.1 - 2.4e-08 34.0 0.0 3.3e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST41726.1 - 5.3e-05 23.0 0.0 6.2e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 EST41726.1 - 0.0018 18.4 0.1 0.0024 18.1 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EST41726.1 - 0.005 17.0 0.1 0.013 15.6 0.1 1.7 1 1 0 1 1 1 1 SANT/Myb-like domain of DAMP1 LSM PF01423.22 EST41727.1 - 1.7e-10 40.4 0.0 2.3e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 LSM domain CEP76-C2 PF15627.6 EST41728.1 - 0.012 15.2 0.1 0.022 14.3 0.1 1.4 1 0 0 1 1 1 0 CEP76 C2 domain DUF3964 PF13107.6 EST41728.1 - 0.053 13.9 0.4 0.17 12.3 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3964) DUF2999 PF11212.8 EST41728.1 - 0.14 12.5 1.1 0.42 10.9 1.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2999) Transglut_core PF01841.19 EST41728.1 - 0.16 12.4 0.0 0.38 11.2 0.0 1.6 1 0 0 1 1 1 0 Transglutaminase-like superfamily SET PF00856.28 EST41730.1 - 0.00027 21.4 1.4 0.00077 19.9 1.2 2.0 1 1 0 1 1 1 1 SET domain DUF1451 PF07295.11 EST41731.1 - 0.0041 17.2 0.2 0.0049 16.9 0.2 1.2 1 0 0 1 1 1 1 Zinc-ribbon containing domain FYVE_2 PF02318.16 EST41731.1 - 0.0099 16.1 0.9 0.015 15.5 0.9 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger Zn_Tnp_IS1595 PF12760.7 EST41731.1 - 0.11 12.4 1.2 0.21 11.6 1.2 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Shugoshin_N PF07558.11 EST41732.1 - 0.001 18.9 3.8 0.83 9.6 0.1 3.7 2 0 0 2 2 2 2 Shugoshin N-terminal coiled-coil region DUF4136 PF13590.6 EST41732.1 - 0.026 15.1 4.8 0.039 14.5 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4136) PHP PF02811.19 EST41733.1 - 4.8e-07 30.2 0.0 6.3e-07 29.8 0.0 1.3 1 1 0 1 1 1 1 PHP domain Lipase_3 PF01764.25 EST41734.1 - 1.4e-10 41.2 0.0 3.5e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 EST41734.1 - 5.9e-06 26.2 0.3 9.9e-06 25.4 0.3 1.4 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 EST41734.1 - 6.4e-06 26.5 0.0 1.3e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.20 EST41734.1 - 3.8e-05 23.5 0.0 6.9e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Cutinase PF01083.22 EST41734.1 - 5.3e-05 23.3 0.5 9e-05 22.5 0.5 1.3 1 0 0 1 1 1 1 Cutinase Abhydrolase_3 PF07859.13 EST41734.1 - 0.0008 19.3 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.14 EST41734.1 - 0.0023 17.4 0.1 0.0043 16.6 0.1 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EST41734.1 - 0.0049 16.7 1.8 0.011 15.6 1.8 1.6 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Hydrolase_4 PF12146.8 EST41734.1 - 0.0074 15.6 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PE-PPE PF08237.11 EST41734.1 - 0.016 14.8 0.1 0.03 13.9 0.1 1.4 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_6 PF12697.7 EST41734.1 - 0.04 14.5 0.0 0.056 14.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Zot PF05707.12 EST41734.1 - 0.054 13.1 0.1 0.087 12.5 0.1 1.4 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) LIP PF03583.14 EST41734.1 - 0.075 12.3 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 Secretory lipase Abhydrolase_8 PF06259.12 EST41734.1 - 0.096 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase Nramp PF01566.18 EST41735.1 - 0.0079 15.2 0.8 0.013 14.6 0.8 1.2 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein DUF3021 PF11457.8 EST41735.1 - 0.04 14.2 0.7 0.04 14.2 0.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) DUF5131 PF07505.11 EST41735.1 - 0.063 12.7 0.2 0.086 12.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF5131) YaeQ PF07152.12 EST41735.1 - 0.08 12.5 0.8 0.15 11.6 0.8 1.4 1 0 0 1 1 1 0 YaeQ protein KLRAQ PF10205.9 EST41735.1 - 0.31 11.3 16.0 0.27 11.5 9.7 3.0 3 1 0 3 3 3 0 Predicted coiled-coil domain-containing protein PRP9_N PF16958.5 EST41735.1 - 0.65 10.0 6.0 0.21 11.6 1.0 2.2 1 1 1 2 2 2 0 Pre-mRNA-splicing factor PRP9 N-terminus Peptidase_S28 PF05577.12 EST41736.1 - 1.9e-88 297.1 3.7 3.4e-88 296.3 3.7 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 EST41736.1 - 2.1e-06 27.6 0.0 4.7e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EST41736.1 - 0.0046 16.3 0.0 0.0078 15.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EST41736.1 - 0.011 15.2 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family TPR_7 PF13176.6 EST41737.1 - 0.39 10.9 2.1 0.85 9.8 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1390 PF07150.11 EST41738.1 - 0.16 11.7 0.2 0.21 11.3 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1390) TM2 PF05154.16 EST41739.1 - 5.3e-08 33.1 14.4 7.1e-08 32.7 14.4 1.2 1 0 0 1 1 1 1 TM2 domain BMFP PF04380.13 EST41740.1 - 0.0016 18.9 0.4 0.0048 17.4 0.4 1.8 1 0 0 1 1 1 1 Membrane fusogenic activity NTNH_C PF08470.10 EST41740.1 - 0.0051 16.7 0.7 0.013 15.4 0.7 1.6 1 0 0 1 1 1 1 Nontoxic nonhaemagglutinin C-terminal DUF4326 PF14216.6 EST41740.1 - 0.13 13.0 0.2 0.46 11.2 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4326) Ycf66_N PF07444.11 EST41741.1 - 0.33 11.1 4.5 2.8 8.1 0.3 2.5 1 1 1 2 2 2 0 Ycf66 protein N-terminus Type_III_YscG PF09477.10 EST41746.1 - 0.018 15.1 0.0 0.042 13.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_20 PF14561.6 EST41746.1 - 0.066 13.6 0.1 0.16 12.4 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3823_C PF18003.1 EST41746.1 - 0.12 13.1 0.7 0.27 12.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3823_C) zf-C2H2 PF00096.26 EST41747.1 - 4.5e-21 74.1 32.8 2.4e-05 24.6 0.2 5.3 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EST41747.1 - 9e-21 72.8 29.9 0.00042 20.9 0.1 5.3 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EST41747.1 - 1.1e-09 38.2 26.8 0.0099 16.3 0.2 6.3 6 0 0 6 6 6 3 Zinc-finger double domain zf-met PF12874.7 EST41747.1 - 5e-09 36.2 22.4 0.14 12.6 0.8 5.5 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EST41747.1 - 1.8e-08 34.5 27.1 0.011 16.0 0.9 5.8 6 0 0 6 6 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EST41747.1 - 7.2e-06 26.3 26.6 0.075 13.4 1.8 5.0 1 1 4 5 5 5 3 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 EST41747.1 - 3.3e-05 23.7 34.1 0.14 12.2 1.8 5.9 5 1 0 5 5 5 3 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 EST41747.1 - 3.6e-05 23.8 23.2 0.14 12.3 5.9 5.0 2 1 3 5 5 5 4 Zinc ribbon domain Elf1 PF05129.13 EST41747.1 - 4.5e-05 23.4 2.0 4.5e-05 23.4 2.0 3.8 2 2 1 3 3 3 2 Transcription elongation factor Elf1 like zf-C2H2_11 PF16622.5 EST41747.1 - 7.9e-05 22.3 21.4 0.063 13.0 0.9 4.6 5 0 0 5 5 4 3 zinc-finger C2H2-type zf_UBZ PF18439.1 EST41747.1 - 0.00016 21.2 17.7 0.9 9.2 0.1 5.4 5 0 0 5 5 5 3 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 EST41747.1 - 0.00041 20.6 2.1 0.00041 20.6 2.1 3.4 2 2 2 4 4 4 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 EST41747.1 - 0.00044 20.5 2.6 0.00044 20.5 2.6 2.8 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-C2H2_9 PF16293.5 EST41747.1 - 0.00065 19.5 9.8 5.9 6.8 0.0 4.9 3 2 2 5 5 5 0 C2H2 type zinc-finger (1 copy) BolA PF01722.18 EST41747.1 - 0.0023 18.2 2.8 0.81 10.0 0.0 3.4 2 1 1 3 3 3 1 BolA-like protein HypA PF01155.19 EST41747.1 - 0.0024 17.9 17.8 0.2 11.7 1.5 4.1 1 1 3 4 4 4 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-FCS PF06467.14 EST41747.1 - 0.0025 17.7 17.5 0.84 9.6 4.5 4.6 4 1 0 4 4 4 1 MYM-type Zinc finger with FCS sequence motif zf-C2H2_3rep PF18868.1 EST41747.1 - 0.0027 18.4 17.1 0.025 15.2 12.0 3.2 1 1 1 2 2 2 1 Zinc finger C2H2-type, 3 repeats DUF2340 PF10209.9 EST41747.1 - 0.0049 17.3 0.8 0.014 15.9 0.3 1.8 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2340) ADK_lid PF05191.14 EST41747.1 - 0.0063 16.5 7.6 1.2 9.2 0.1 3.7 3 1 1 4 4 4 1 Adenylate kinase, active site lid LIM PF00412.22 EST41747.1 - 0.0079 16.4 22.6 1.4 9.2 2.0 4.8 2 2 2 4 4 4 1 LIM domain HNH PF01844.23 EST41747.1 - 0.01 16.0 22.1 5.3 7.3 0.4 5.1 5 0 0 5 5 5 0 HNH endonuclease DZR PF12773.7 EST41747.1 - 0.011 15.8 16.1 7.1e+02 0.3 14.9 3.1 1 1 0 1 1 1 0 Double zinc ribbon GAGA PF09237.11 EST41747.1 - 0.011 15.5 2.2 0.82 9.5 0.3 2.6 1 1 1 2 2 2 0 GAGA factor zinc_ribbon_15 PF17032.5 EST41747.1 - 0.013 16.2 16.8 0.42 11.4 4.6 3.0 1 1 0 2 2 2 0 zinc-ribbon family HNH_5 PF14279.6 EST41747.1 - 0.021 14.7 17.4 0.25 11.2 3.6 4.2 4 0 0 4 4 4 0 HNH endonuclease zf_C2H2_ZHX PF18387.1 EST41747.1 - 0.035 13.8 2.2 0.035 13.8 2.2 4.7 4 1 1 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF3268 PF11672.8 EST41747.1 - 0.049 14.0 9.0 0.71 10.2 1.2 3.1 3 0 0 3 3 3 0 zinc-finger-containing domain zf-RRN7 PF11781.8 EST41747.1 - 0.053 13.2 13.8 2 8.2 0.2 5.0 5 0 0 5 5 5 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zinc_ribbon_4 PF13717.6 EST41747.1 - 0.073 13.0 17.3 8.7 6.4 0.1 5.1 4 1 0 4 4 4 0 zinc-ribbon domain Prok-RING_1 PF14446.6 EST41747.1 - 0.083 12.8 20.8 1.3 9.0 3.3 5.0 3 2 0 3 3 3 0 Prokaryotic RING finger family 1 Ta0938 PF11494.8 EST41747.1 - 0.094 13.0 0.1 0.094 13.0 0.1 3.2 1 1 2 3 3 3 0 Ta0938 STPPase_N PF16891.5 EST41747.1 - 0.14 12.6 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain DUF4524 PF15025.6 EST41747.1 - 0.21 11.3 3.8 0.25 11.1 1.5 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4524) zf_C2H2_10 PF18414.1 EST41747.1 - 0.26 10.9 5.4 3.5 7.3 0.0 3.8 3 0 0 3 3 3 0 C2H2 type zinc-finger YhfH PF14149.6 EST41747.1 - 0.26 11.3 13.4 16 5.6 0.3 4.5 4 0 0 4 4 4 0 YhfH-like protein zf-C2HC_2 PF13913.6 EST41747.1 - 0.26 11.2 0.2 0.26 11.2 0.2 5.1 5 1 0 5 5 5 0 zinc-finger of a C2HC-type zinc-ribbons_6 PF07191.12 EST41747.1 - 0.44 10.6 20.2 3.5 7.7 4.9 4.3 1 1 2 3 3 3 0 zinc-ribbons zinc_ribbon_9 PF14369.6 EST41747.1 - 0.47 10.7 0.1 0.47 10.7 0.1 4.7 6 0 0 6 6 5 0 zinc-ribbon zinc_ribbon_5 PF13719.6 EST41747.1 - 0.85 9.4 0.0 0.85 9.4 0.0 4.7 5 0 0 5 5 4 0 zinc-ribbon domain RNA_POL_M_15KD PF02150.16 EST41747.1 - 0.86 9.5 15.2 5.9 6.9 0.1 4.6 5 0 0 5 5 5 0 RNA polymerases M/15 Kd subunit Zn-C2H2_12 PF18112.1 EST41747.1 - 0.88 10.1 16.0 5.9 7.4 0.8 5.1 5 0 0 5 5 5 0 Autophagy receptor zinc finger-C2H2 domain zf-BED PF02892.15 EST41747.1 - 1 9.5 23.2 2.3 8.3 0.7 5.2 2 2 3 5 5 5 0 BED zinc finger DUF983 PF06170.12 EST41747.1 - 2.2 8.7 15.5 9.6 6.7 0.1 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF983) Terminase_GpA PF05876.12 EST41747.1 - 2.5 6.5 11.1 0.13 10.8 1.1 2.3 1 1 0 2 2 2 0 Phage terminase large subunit (GpA) TF_Zn_Ribbon PF08271.12 EST41747.1 - 4.9 6.8 20.7 2.2 7.8 3.0 4.5 3 2 0 3 3 3 0 TFIIB zinc-binding DUF2225 PF09986.9 EST41747.1 - 8.4 6.0 16.1 1.6 8.4 0.2 4.1 2 2 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) OrfB_Zn_ribbon PF07282.11 EST41747.1 - 9.9 6.2 21.0 4.1 7.4 3.2 4.6 1 1 4 5 5 5 0 Putative transposase DNA-binding domain BING4CT PF08149.11 EST41748.1 - 1.2e-13 50.6 0.0 3.3e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 EST41748.1 - 6e-05 23.3 0.0 1.4 9.3 0.0 3.6 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain AAA_6 PF12774.7 EST41750.1 - 7.5e-21 74.4 7.5 7.5e-21 74.4 7.5 4.7 6 0 0 6 6 6 1 Hydrolytic ATP binding site of dynein motor region MT PF12777.7 EST41750.1 - 4.2e-19 68.8 3.7 4.2e-19 68.8 3.7 2.1 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 EST41750.1 - 3.5e-07 30.3 0.0 0.064 13.3 0.0 3.8 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) NACHT PF05729.12 EST41750.1 - 0.017 15.0 1.6 0.27 11.2 0.1 3.6 3 0 0 3 3 3 0 NACHT domain AAA_16 PF13191.6 EST41750.1 - 0.03 14.7 3.2 14 6.0 0.0 5.2 5 0 0 5 5 5 0 AAA ATPase domain RNA_helicase PF00910.22 EST41750.1 - 0.17 12.3 5.0 23 5.4 0.0 5.1 4 0 0 4 4 4 0 RNA helicase AAA PF00004.29 EST41750.1 - 0.73 10.3 9.3 20 5.6 0.0 4.9 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EST41750.1 - 1.9 8.8 5.8 12 6.2 0.0 4.9 4 1 1 5 5 5 0 AAA domain Hus1 PF04005.12 EST41751.1 - 0.055 12.6 1.9 0.3 10.2 0.4 2.1 2 0 0 2 2 2 0 Hus1-like protein Myotub-related PF06602.14 EST41752.1 - 3.8e-19 68.9 7.0 2.1e-17 63.1 7.1 2.3 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain Bac_export_2 PF01312.19 EST41752.1 - 0.092 11.9 0.3 0.17 11.1 0.3 1.3 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Pkinase PF00069.25 EST41753.1 - 7.9e-75 251.6 0.4 2.2e-74 250.1 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST41753.1 - 2.8e-45 154.6 0.0 8.6e-44 149.8 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase KA1 PF02149.19 EST41753.1 - 8e-10 38.4 1.3 2.7e-09 36.7 0.1 2.5 3 0 0 3 3 3 1 Kinase associated domain 1 Kinase-like PF14531.6 EST41753.1 - 5.1e-07 29.3 0.0 1.2e-05 24.8 0.0 2.6 2 1 1 3 3 3 1 Kinase-like Seadorna_VP7 PF07387.11 EST41753.1 - 0.0073 15.4 0.0 0.019 14.0 0.0 1.7 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 EST41753.1 - 0.011 14.7 0.3 0.028 13.4 0.3 1.8 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EST41753.1 - 0.047 13.6 0.1 0.15 11.9 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family SpoVIF PF14069.6 EST41754.1 - 0.057 13.2 2.5 0.13 12.0 1.3 2.2 1 1 1 2 2 2 0 Stage VI sporulation protein F DUF5582 PF17819.1 EST41754.1 - 0.12 12.8 4.7 0.14 12.6 2.9 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5582) FAM60A PF15396.6 EST41754.1 - 0.23 11.4 3.6 0.32 11.0 3.6 1.2 1 0 0 1 1 1 0 Protein Family FAM60A YjcB PF15940.5 EST41756.1 - 0.052 13.7 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function NUDIX PF00293.28 EST41758.1 - 5.8e-12 45.8 0.1 1.1e-11 44.9 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.11 EST41758.1 - 0.027 14.1 2.3 0.046 13.4 1.2 2.1 2 1 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_2 PF13240.6 EST41758.1 - 0.029 14.1 1.8 0.19 11.5 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 EST41758.1 - 0.05 13.6 2.2 0.05 13.6 2.2 2.0 1 1 1 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 EST41758.1 - 0.06 13.3 4.8 14 5.7 5.7 3.1 2 1 0 2 2 2 0 zinc-ribbons Nudix_N_2 PF14803.6 EST41758.1 - 0.07 13.1 6.1 0.13 12.2 0.3 2.7 3 0 0 3 3 3 0 Nudix N-terminal zf-ribbon_3 PF13248.6 EST41758.1 - 0.092 12.2 1.1 3.7 7.1 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain RecR PF02132.15 EST41758.1 - 0.11 12.1 2.2 0.14 11.7 0.1 2.3 3 0 0 3 3 3 0 RecR protein C1_1 PF00130.22 EST41758.1 - 1.4 8.8 7.4 1.1 9.2 5.3 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Palm_thioest PF02089.15 EST41761.1 - 7.2e-23 81.7 0.0 4.9e-22 79.0 0.0 1.9 1 1 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 EST41761.1 - 1.3e-05 24.7 0.1 0.0002 20.8 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) UPF0227 PF05728.12 EST41761.1 - 0.00024 21.1 0.1 0.00043 20.3 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) DUF676 PF05057.14 EST41761.1 - 0.00033 20.2 0.0 0.86 9.1 0.0 2.1 2 0 0 2 2 2 2 Putative serine esterase (DUF676) PGAP1 PF07819.13 EST41761.1 - 0.001 18.9 0.0 0.0063 16.3 0.0 1.9 1 1 0 2 2 2 1 PGAP1-like protein Abhydrolase_1 PF00561.20 EST41761.1 - 0.0058 16.3 0.0 0.023 14.4 0.1 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EST41761.1 - 0.024 13.9 0.0 0.11 11.7 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Thioesterase PF00975.20 EST41761.1 - 0.031 14.4 0.0 0.044 13.9 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain FSH1 PF03959.13 EST41761.1 - 0.065 12.9 0.1 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 EST41761.1 - 0.087 13.4 0.0 0.09 13.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_2 PF01674.18 EST41761.1 - 0.11 11.9 0.0 2.2 7.7 0.0 2.7 2 1 0 2 2 2 0 Lipase (class 2) DUF4609 PF15382.6 EST41762.1 - 2 8.4 6.0 13 5.7 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4609) Enkurin PF13864.6 EST41763.1 - 2.6e-19 69.5 4.8 5e-19 68.5 4.8 1.5 1 0 0 1 1 1 1 Calmodulin-binding CREPT PF16566.5 EST41763.1 - 0.037 14.2 1.3 0.083 13.1 0.9 1.7 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour DUF5344 PF17279.2 EST41763.1 - 0.071 13.7 2.2 0.2 12.3 2.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5344) DUF5113 PF17140.4 EST41763.1 - 0.09 12.6 0.2 0.18 11.6 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5113) DUF3886 PF13025.6 EST41763.1 - 0.21 11.8 6.2 0.51 10.6 6.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) Terminase_6 PF03237.15 EST41764.1 - 0.025 14.3 0.8 0.14 11.8 0.2 2.0 1 1 1 2 2 2 0 Terminase-like family PTA_PTB PF01515.19 EST41764.1 - 0.097 12.0 0.2 0.12 11.7 0.2 1.2 1 0 0 1 1 1 0 Phosphate acetyl/butaryl transferase Cullin_Nedd8 PF10557.9 EST41767.1 - 5.4 7.1 11.0 20 5.3 4.5 4.0 2 1 1 3 3 3 0 Cullin protein neddylation domain PPP1R35_C PF15503.6 EST41768.1 - 0.0026 17.6 0.8 0.011 15.6 0.1 2.3 2 0 0 2 2 2 1 Protein phosphatase 1 regulatory subunit 35 C-terminus Ank_3 PF13606.6 EST41768.1 - 0.028 14.9 0.0 0.38 11.4 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat Ank PF00023.30 EST41768.1 - 0.043 14.3 0.0 0.13 12.7 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeat PCNA_N PF00705.18 EST41770.1 - 1.1e-22 80.1 0.6 1.9e-22 79.3 0.4 1.5 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 EST41770.1 - 8.9e-21 74.4 0.2 3e-19 69.5 0.0 2.2 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 EST41770.1 - 0.00014 21.4 0.5 0.00029 20.4 0.5 1.5 1 1 0 1 1 1 1 Rad9 Rad1 PF02144.16 EST41770.1 - 0.00035 19.7 2.6 0.0031 16.6 0.4 2.0 1 1 1 2 2 2 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 EST41770.1 - 0.0036 16.5 0.6 0.012 14.8 0.4 1.8 1 1 1 2 2 2 1 Hus1-like protein ChuX_HutX PF06228.13 EST41770.1 - 0.059 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Haem utilisation ChuX/HutX Neugrin PF06413.11 EST41771.1 - 0.71 9.8 11.6 3.6 7.5 1.0 2.7 2 1 0 2 2 2 0 Neugrin AATF-Che1 PF13339.6 EST41772.1 - 1.3 9.7 6.0 3 8.5 6.0 1.9 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Hexapep PF00132.24 EST41773.1 - 4.1e-18 64.3 10.7 9.6e-08 31.5 0.7 4.1 2 1 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 EST41773.1 - 0.00058 18.9 0.6 0.0029 16.6 0.3 2.2 1 1 1 2 2 2 1 L-fucokinase DUF4954 PF16314.5 EST41773.1 - 0.00098 17.4 0.6 0.0014 16.9 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 EST41773.1 - 0.0031 17.2 6.5 2.1 8.2 0.3 3.8 3 1 1 4 4 4 3 Hexapeptide repeat of succinyl-transferase tRNA_m1G_MT PF01746.21 EST41774.1 - 5.4e-12 45.8 0.6 1.4e-11 44.5 0.0 2.0 2 1 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase Lipase_GDSL PF00657.22 EST41774.1 - 0.0031 17.5 0.2 0.0055 16.7 0.2 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DFRP_C PF16543.5 EST41774.1 - 0.076 13.5 2.1 2.3 8.8 3.7 2.4 3 0 0 3 3 3 0 DRG Family Regulatory Proteins, Tma46 SRP_SPB PF02978.19 EST41774.1 - 0.12 13.0 0.9 1.4 9.6 0.2 2.6 2 0 0 2 2 2 0 Signal peptide binding domain zf-CHY PF05495.12 EST41776.1 - 4.1e-13 49.6 22.2 4.1e-13 49.6 22.2 4.2 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 EST41776.1 - 4.2e-06 27.0 7.2 4.2e-06 27.0 7.2 5.3 4 2 1 5 5 5 1 Ring finger domain zf-RING_5 PF14634.6 EST41776.1 - 0.0015 18.5 8.0 0.0015 18.5 8.0 5.9 4 2 2 6 6 6 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EST41776.1 - 0.017 14.9 9.3 0.017 14.9 9.3 5.8 2 1 3 5 5 5 0 Zinc finger, C3HC4 type (RING finger) Dynein_attach_N PF15867.5 EST41777.1 - 0.12 12.4 0.6 0.26 11.3 0.6 1.6 1 0 0 1 1 1 0 Dynein attachment factor N-terminus EAP30 PF04157.16 EST41778.1 - 8.2e-15 54.7 1.6 2e-14 53.4 1.6 1.5 1 1 0 1 1 1 1 EAP30/Vps36 family COG2 PF06148.11 EST41778.1 - 0.0095 16.0 2.8 0.037 14.1 1.6 2.1 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 FliL PF03748.14 EST41778.1 - 0.011 16.3 0.0 0.039 14.6 0.0 2.0 1 1 0 1 1 1 0 Flagellar basal body-associated protein FliL DUF4504 PF14953.6 EST41778.1 - 0.062 12.7 1.8 2.1 7.7 0.6 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4504) LON_substr_bdg PF02190.16 EST41778.1 - 1.2 9.0 3.9 0.59 10.0 1.0 1.8 2 0 0 2 2 2 0 ATP-dependent protease La (LON) substrate-binding domain Holin_BhlA PF10960.8 EST41779.1 - 1.1 9.2 7.7 1.4 9.0 2.7 3.3 2 1 0 2 2 2 0 BhlA holin family SNARE PF05739.19 EST41780.1 - 2.7e-05 24.1 1.7 7.6e-05 22.6 0.0 2.6 3 0 0 3 3 3 1 SNARE domain DUF1993 PF09351.10 EST41780.1 - 0.0007 19.8 3.8 0.012 15.8 0.8 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF1993) Med30 PF11315.8 EST41780.1 - 0.21 11.8 12.7 0.22 11.7 1.9 2.2 1 1 1 2 2 2 0 Mediator complex subunit 30 EzrA PF06160.12 EST41780.1 - 0.23 9.6 16.2 0.49 8.5 16.2 1.5 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA DUF1664 PF07889.12 EST41780.1 - 1 9.4 12.5 1.7 8.7 5.3 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Spectrin PF00435.21 EST41780.1 - 1.2 9.6 11.0 0.13 12.7 5.7 2.0 1 1 1 2 2 2 0 Spectrin repeat Fes1 PF08609.10 EST41780.1 - 1.4 9.8 6.7 0.55 11.1 3.4 1.9 1 1 0 2 2 2 0 Nucleotide exchange factor Fes1 NPV_P10 PF05531.12 EST41780.1 - 1.8 9.0 10.7 0.4 11.2 1.0 3.3 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF2203 PF09969.9 EST41780.1 - 5.1 7.8 9.8 14 6.4 1.2 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) bZIP_1 PF00170.21 EST41780.1 - 7.5 6.7 8.9 9.4 6.4 0.4 3.3 3 1 1 4 4 4 0 bZIP transcription factor Lipase_3 PF01764.25 EST41782.1 - 2e-09 37.4 0.2 9.8e-09 35.2 0.0 2.2 2 1 0 2 2 2 1 Lipase (class 3) PGAP1 PF07819.13 EST41782.1 - 0.0077 16.0 0.1 0.079 12.7 0.0 2.2 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_1 PF00561.20 EST41782.1 - 0.0081 15.8 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EST41782.1 - 0.022 14.5 0.0 0.05 13.4 0.0 1.6 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EST41782.1 - 0.054 14.1 0.0 0.073 13.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family TMF_TATA_bd PF12325.8 EST41784.1 - 0.0036 17.5 33.0 0.0077 16.4 6.1 3.4 1 1 2 3 3 3 1 TATA element modulatory factor 1 TATA binding BLOC1_2 PF10046.9 EST41784.1 - 0.1 12.9 30.6 1 9.7 3.0 4.5 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 EST41784.1 - 0.14 11.0 35.6 0.82 8.5 21.7 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Dak2 PF02734.17 EST41784.1 - 0.15 11.9 3.2 0.26 11.2 0.0 2.3 2 1 0 2 2 2 0 DAK2 domain Ax_dynein_light PF10211.9 EST41784.1 - 0.18 11.8 30.9 2.2 8.2 15.3 3.0 2 1 0 2 2 2 0 Axonemal dynein light chain DUF3138 PF11336.8 EST41784.1 - 0.2 10.2 5.9 0.2 10.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) DUF3584 PF12128.8 EST41784.1 - 0.21 9.1 32.2 0.28 8.7 32.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ERM PF00769.19 EST41784.1 - 0.39 10.5 33.5 0.84 9.4 33.4 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family GAS PF13851.6 EST41784.1 - 0.84 9.0 36.4 0.96 8.8 35.4 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Macoilin PF09726.9 EST41784.1 - 0.88 8.1 28.0 1.1 7.7 28.0 1.1 1 0 0 1 1 1 0 Macoilin family YabA PF06156.13 EST41784.1 - 1.8 9.2 28.5 5.3 7.7 4.3 3.5 1 1 3 4 4 4 0 Initiation control protein YabA Sec34 PF04136.15 EST41784.1 - 2 8.3 27.2 1.4 8.8 2.9 3.4 1 1 2 3 3 3 0 Sec34-like family APG6_N PF17675.1 EST41784.1 - 2.7 8.5 37.4 0.17 12.4 14.2 3.6 1 1 2 3 3 3 0 Apg6 coiled-coil region DUF812 PF05667.11 EST41784.1 - 3.5 6.4 41.3 4.9 5.9 30.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) FUSC PF04632.12 EST41784.1 - 3.8 5.9 10.3 8 4.9 10.1 1.5 1 1 1 2 2 2 0 Fusaric acid resistance protein family ADIP PF11559.8 EST41784.1 - 4 7.5 39.2 7 6.7 15.6 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding NPV_P10 PF05531.12 EST41784.1 - 4.4 7.8 24.0 3 8.4 7.9 3.5 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Tweety PF04906.13 EST41784.1 - 5.3 5.6 20.9 0.28 9.8 5.4 2.5 1 1 1 3 3 3 0 Tweety DUF2381 PF09544.10 EST41784.1 - 6 6.3 10.2 0.48 9.9 3.4 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2381) CARM1 PF11531.8 EST41784.1 - 6.2 7.0 8.8 3.2 8.0 1.0 3.5 3 1 0 3 3 3 0 Coactivator-associated arginine methyltransferase 1 N terminal Tropomyosin_1 PF12718.7 EST41784.1 - 6.3 7.0 36.2 34 4.6 8.2 3.3 1 1 2 3 3 3 0 Tropomyosin like GrpE PF01025.19 EST41784.1 - 6.8 6.3 30.3 25 4.5 9.9 3.1 1 1 1 2 2 2 0 GrpE Spectrin PF00435.21 EST41784.1 - 6.8 7.2 31.0 4 8.0 8.2 3.5 1 1 2 3 3 3 0 Spectrin repeat DUF724 PF05266.14 EST41784.1 - 8.8 6.1 28.9 2.7 7.8 12.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF724) GILT PF03227.16 EST41787.1 - 3.2e-06 27.4 0.1 9.9e-06 25.8 0.1 1.9 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) LRRNT_2 PF08263.12 EST41787.1 - 0.018 15.3 0.8 0.037 14.3 0.8 1.5 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain HtaA PF04213.13 EST41787.1 - 0.11 13.0 0.4 1.6 9.2 0.2 2.6 2 1 0 2 2 2 0 Htaa HPS3_C PF14763.6 EST41789.1 - 0.035 13.5 0.0 0.041 13.2 0.0 1.1 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3, C-terminal DUF4500 PF14937.6 EST41789.1 - 0.056 13.5 0.2 0.086 12.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) tRNA_m1G_MT PF01746.21 EST41790.1 - 1.5e-12 47.6 0.0 3.2e-12 46.6 0.0 1.6 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase LRR_4 PF12799.7 EST41791.1 - 7.1e-15 54.9 16.3 1.9e-07 31.2 0.7 4.1 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EST41791.1 - 3.5e-14 52.7 0.5 6.7e-08 32.2 0.5 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 EST41791.1 - 9.8e-11 41.3 12.5 6.1e-05 22.7 3.4 4.2 2 1 2 4 4 4 4 Leucine rich repeat LRR_6 PF13516.6 EST41791.1 - 0.076 13.1 10.1 5.1 7.4 0.0 4.6 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 EST41791.1 - 1.9 9.3 9.1 90 4.3 0.1 5.1 4 1 1 5 5 5 0 Leucine Rich Repeat VWA PF00092.28 EST41792.1 - 1.8e-12 47.8 0.8 6e-12 46.2 0.8 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EST41792.1 - 1.1e-08 35.7 0.1 1.8e-07 31.7 0.1 2.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 EST41792.1 - 9.4e-05 22.4 0.0 0.0018 18.2 0.0 2.5 3 0 0 3 3 3 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 EST41792.1 - 0.017 15.2 0.6 0.19 11.9 0.6 2.3 1 1 0 1 1 1 0 vWA found in TerF C terminus IQ PF00612.27 EST41793.1 - 0.2 11.6 0.0 0.16 11.9 2.2 20.2 26 0 0 26 26 26 0 IQ calmodulin-binding motif TPR_10 PF13374.6 EST41793.1 - 0.36 10.8 1.3 1.3 9.0 1.3 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Pkinase PF00069.25 EST41794.1 - 6.1e-45 153.6 0.1 2.6e-44 151.6 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST41794.1 - 1.5e-23 83.5 0.0 3.4e-20 72.4 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 EST41794.1 - 0.00038 19.9 0.1 0.0009 18.6 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1758 PF05585.12 EST41794.1 - 0.014 15.2 0.1 0.45 10.3 0.0 2.4 2 0 0 2 2 2 0 Putative peptidase (DUF1758) Mis12 PF05859.12 EST41794.1 - 0.026 14.6 0.3 0.054 13.5 0.3 1.5 1 0 0 1 1 1 0 Mis12 protein Endonuc_subdom PF09062.10 EST41794.1 - 0.064 14.1 0.9 0.21 12.4 0.1 2.3 2 0 0 2 2 2 0 PI-PfuI Endonuclease subdomain ABC1 PF03109.16 EST41794.1 - 0.076 13.2 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 ABC1 family FAE1_CUT1_RppA PF08392.12 EST41795.1 - 5.4e-86 288.5 0.0 7.2e-86 288.1 0.0 1.1 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.10 EST41795.1 - 2.3e-10 40.5 0.0 5.1e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Chal_sti_synt_C PF02797.15 EST41795.1 - 3.4e-10 40.1 0.0 6.6e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III PF08545.10 EST41795.1 - 0.17 11.8 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HPS3_C PF14763.6 EST41796.1 - 0.078 12.3 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3, C-terminal DUF4500 PF14937.6 EST41796.1 - 0.084 12.9 0.2 0.16 12.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) COX6C PF02937.15 EST41796.1 - 0.79 9.9 3.0 1.2 9.3 0.5 2.5 2 1 0 2 2 2 0 Cytochrome c oxidase subunit VIc Chromo PF00385.24 EST41799.1 - 6.5e-08 32.4 0.2 2.2e-07 30.6 0.2 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain HMG_box PF00505.19 EST41800.1 - 1.4e-09 38.3 1.6 1.4e-09 38.3 1.6 3.3 3 1 1 4 4 4 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EST41800.1 - 2.1e-09 37.8 3.9 2.1e-09 37.8 3.9 2.2 1 1 1 2 2 2 1 HMG-box domain GIY-YIG PF01541.24 EST41800.1 - 0.14 12.5 3.0 0.29 11.5 3.0 1.6 1 0 0 1 1 1 0 GIY-YIG catalytic domain S-l_SbsC_C PF18316.1 EST41801.1 - 0.022 15.3 0.3 0.036 14.6 0.3 1.3 1 0 0 1 1 1 0 S-layer protein SbsC C-terminal domain PKHD_C PF18331.1 EST41803.1 - 0.77 9.9 7.5 12 6.1 0.0 3.8 4 1 0 4 4 4 0 PKHD-type hydroxylase C-terminal domain DUF3800 PF12686.7 EST41803.1 - 0.82 10.3 4.4 11 6.7 4.4 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) Spc7 PF08317.11 EST41803.1 - 0.92 8.3 43.6 0.012 14.5 28.7 2.2 1 1 0 2 2 2 0 Spc7 kinetochore protein Latarcin PF10279.9 EST41803.1 - 2.3 8.7 13.3 2.8 8.4 9.6 2.7 2 1 0 2 2 2 0 Latarcin precursor Peptidase_M18 PF02127.15 EST41806.1 - 5.7e-60 203.3 0.0 2.5e-59 201.2 0.0 1.7 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 EST41806.1 - 4.3e-06 26.0 0.1 2.8e-05 23.3 0.1 1.9 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase TRM PF02005.16 EST41808.1 - 3.6e-90 302.9 0.8 4.6e-90 302.5 0.8 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase PUF PF00806.19 EST41809.1 - 1.7e-23 80.9 17.9 4.8e-06 26.0 0.1 7.6 7 1 1 8 8 8 6 Pumilio-family RNA binding repeat CPL PF08144.11 EST41809.1 - 0.67 10.3 2.2 5 7.5 0.1 3.1 2 1 2 4 4 4 0 CPL (NUC119) domain Varsurf_PPLC PF03490.13 EST41811.1 - 0.19 11.7 0.1 0.45 10.5 0.1 1.6 1 0 0 1 1 1 0 Variant-surface-glycoprotein phospholipase C EF-hand_1 PF00036.32 EST41812.1 - 1.3e-31 105.8 15.0 4.3e-09 35.3 1.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EST41812.1 - 7.6e-29 100.0 9.9 2.7e-14 53.4 3.9 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EST41812.1 - 3.9e-25 87.5 15.6 3.5e-13 49.2 1.0 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 EST41812.1 - 1.2e-24 84.1 10.4 1.6e-08 33.8 0.1 4.3 4 1 0 4 4 4 4 EF-hand domain EF-hand_9 PF14658.6 EST41812.1 - 5.9e-17 61.8 0.1 4.6e-07 30.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EST41812.1 - 1.9e-12 46.1 17.1 5e-06 25.8 0.2 4.7 4 1 1 5 5 5 3 EF hand EF-hand_4 PF12763.7 EST41812.1 - 7.9e-06 25.8 4.8 0.046 13.7 0.6 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_14 PF17959.1 EST41812.1 - 0.00059 20.1 1.0 1.3 9.4 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain SurA_N_3 PF13624.6 EST41812.1 - 0.004 17.0 0.6 0.17 11.7 0.3 2.1 1 1 1 2 2 2 1 SurA N-terminal domain SPARC_Ca_bdg PF10591.9 EST41812.1 - 0.0072 16.6 0.4 0.66 10.3 0.2 2.1 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region SurA_N_2 PF13623.6 EST41812.1 - 0.023 14.5 0.4 0.85 9.5 0.2 2.3 1 1 0 2 2 2 0 SurA N-terminal domain Dockerin_1 PF00404.18 EST41812.1 - 0.031 14.5 1.7 0.32 11.2 0.1 2.6 2 1 0 2 2 2 0 Dockerin type I domain DUF3911 PF13050.6 EST41812.1 - 0.087 13.0 0.1 0.81 9.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3911) DUF853 PF05872.12 EST41812.1 - 0.088 11.4 0.1 4.4 5.8 0.0 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) DUF3349 PF11829.8 EST41812.1 - 0.098 13.4 0.2 14 6.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) Caleosin PF05042.13 EST41812.1 - 0.11 12.4 0.4 5.3 6.9 0.3 3.2 1 1 1 2 2 2 0 Caleosin related protein EF-hand_10 PF14788.6 EST41812.1 - 0.11 12.3 4.0 0.84 9.5 0.9 2.8 2 1 1 3 3 3 0 EF hand DUF21 PF01595.20 EST41812.1 - 0.35 10.5 0.4 1.2 8.8 0.2 1.9 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain UBA_2 PF08587.11 EST41812.1 - 0.56 10.4 3.3 18 5.6 0.0 3.3 3 1 0 3 3 3 0 Ubiquitin associated domain (UBA) Peptidase_M18 PF02127.15 EST41813.1 - 9.2e-06 24.7 0.1 9.9e-06 24.6 0.1 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Alpha-amylase PF00128.24 EST41814.1 - 4.3e-07 29.8 0.0 3e-05 23.8 0.0 2.3 3 0 0 3 3 3 2 Alpha amylase, catalytic domain IFT57 PF10498.9 EST41816.1 - 1.9e-47 162.0 18.9 2.9e-47 161.4 18.9 1.2 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Tropomyosin PF00261.20 EST41816.1 - 0.11 11.8 10.5 0.29 10.5 2.1 2.4 2 0 0 2 2 2 0 Tropomyosin RVT_connect PF06815.13 EST41816.1 - 0.18 12.1 2.4 0.25 11.6 0.9 1.9 1 1 1 2 2 2 0 Reverse transcriptase connection domain DUF1993 PF09351.10 EST41816.1 - 0.19 11.9 2.4 0.42 10.7 2.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) DUF3552 PF12072.8 EST41816.1 - 0.53 9.7 13.3 0.19 11.1 9.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) Rootletin PF15035.6 EST41816.1 - 0.63 10.0 19.1 0.77 9.7 12.3 2.3 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DASH_Spc19 PF08287.11 EST41816.1 - 0.7 9.8 17.3 0.17 11.8 8.2 3.3 1 1 2 3 3 3 0 Spc19 Phlebovirus_NSM PF07246.11 EST41816.1 - 0.95 8.8 11.3 0.05 13.0 4.7 1.9 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M CHD5 PF04420.14 EST41816.1 - 1 9.2 8.9 0.21 11.4 1.3 2.5 2 0 0 2 2 2 0 CHD5-like protein DUF1664 PF07889.12 EST41816.1 - 1.6 8.8 10.1 7.1 6.7 0.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Snapin_Pallidin PF14712.6 EST41816.1 - 1.9 9.0 17.4 0.29 11.6 2.8 4.4 2 1 2 4 4 4 0 Snapin/Pallidin TMPIT PF07851.13 EST41816.1 - 2.9 7.1 10.4 1 8.5 7.5 1.6 1 1 1 2 2 2 0 TMPIT-like protein Laminin_II PF06009.12 EST41816.1 - 2.9 7.9 14.4 2.4 8.2 8.2 2.5 1 1 1 2 2 2 0 Laminin Domain II Occludin_ELL PF07303.13 EST41816.1 - 3 8.6 8.8 11 6.8 0.3 2.9 1 1 1 2 2 2 0 Occludin homology domain Nitroreductase PF00881.24 EST41818.1 - 1.1e-17 64.6 0.0 1.1e-10 41.8 0.0 2.1 1 1 1 2 2 2 2 Nitroreductase family TM1586_NiRdase PF14512.6 EST41818.1 - 0.015 14.9 0.0 0.33 10.5 0.0 2.2 1 1 1 2 2 2 0 Putative TM nitroreductase Nop14 PF04147.12 EST41819.1 - 1.5e-06 26.8 48.7 2.4e-05 22.8 4.5 4.1 1 1 3 4 4 4 2 Nop14-like family 2-ph_phosp PF04029.14 EST41819.1 - 0.075 12.2 1.2 0.14 11.3 0.4 1.9 2 0 0 2 2 2 0 2-phosphosulpholactate phosphatase DUF575 PF04746.12 EST41819.1 - 6.1 7.2 6.3 15 5.9 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF575) DUF724 PF05266.14 EST41821.1 - 0.0047 16.8 16.2 0.06 13.2 8.5 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF724) Exonuc_VII_L PF02601.15 EST41821.1 - 1 8.9 6.4 1.4 8.5 6.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit RNA_pol_L_2 PF13656.6 EST41822.1 - 9e-12 44.6 0.2 1.1e-11 44.3 0.2 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Ribosomal_L26 PF16906.5 EST41822.1 - 0.051 14.0 0.0 0.07 13.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal proteins L26 eukaryotic, L24P archaeal DUF2746 PF10874.8 EST41823.1 - 4.1 7.9 7.4 8.5 6.9 0.4 3.8 2 2 2 4 4 4 0 Protein of unknown function (DUF2746) DUF2935 PF11155.8 EST41823.1 - 4.8 7.5 15.7 35 4.8 0.8 4.4 1 1 0 2 2 2 0 Domain of unknown function (DUF2935) Herpes_IE2_3 PF03361.14 EST41823.1 - 5.2 6.9 14.5 2.7 7.8 2.7 3.2 2 1 0 3 3 3 0 Herpes virus intermediate/early protein 2/3 Fez1 PF06818.15 EST41823.1 - 6.4 7.2 38.4 10 6.5 17.1 3.4 1 1 3 4 4 4 0 Fez1 Myb_DNA-binding PF00249.31 EST41824.1 - 3.3e-05 24.0 0.0 8.1e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain FCD PF07729.12 EST41824.1 - 0.058 13.8 0.2 0.16 12.4 0.1 1.7 2 0 0 2 2 2 0 FCD domain DUF4247 PF14042.6 EST41824.1 - 0.066 13.9 0.4 0.085 13.5 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4247) DUF2285 PF10074.9 EST41824.1 - 0.13 12.9 0.2 0.19 12.4 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2285) Sulfotransfer_3 PF13469.6 EST41824.1 - 0.23 11.8 2.6 0.36 11.2 2.6 1.2 1 0 0 1 1 1 0 Sulfotransferase family WD40 PF00400.32 EST41825.1 - 6.6e-09 36.3 0.0 9.9e-05 23.1 0.0 3.0 2 0 0 2 2 2 2 WD domain, G-beta repeat Katanin_con80 PF13925.6 EST41825.1 - 0.00035 20.7 0.7 0.00076 19.6 0.7 1.5 1 1 0 1 1 1 1 con80 domain of Katanin ANAPC4_WD40 PF12894.7 EST41825.1 - 0.003 17.8 0.0 0.051 13.9 0.0 2.7 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nup54 PF13874.6 EST41826.1 - 1.1e-05 25.5 4.9 1.9e-05 24.8 4.9 1.3 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 CENP-H PF05837.12 EST41826.1 - 0.046 14.1 4.8 0.69 10.3 6.4 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Imm7 PF15585.6 EST41826.1 - 0.093 13.0 0.3 0.2 11.9 0.3 1.5 1 0 0 1 1 1 0 Immunity protein 7 PRD PF00874.20 EST41826.1 - 5.5 7.4 9.7 12 6.3 1.6 2.4 1 1 1 2 2 2 0 PRD domain BLOC1_2 PF10046.9 EST41827.1 - 9.7e-05 22.6 13.7 0.021 15.1 1.2 2.9 1 1 2 3 3 3 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 ADIP PF11559.8 EST41827.1 - 0.0086 16.2 21.6 0.28 11.3 7.5 2.1 1 1 1 2 2 2 2 Afadin- and alpha -actinin-Binding SF3A3 PF16837.5 EST41827.1 - 0.16 12.5 0.5 0.16 12.5 0.5 1.8 2 1 0 2 2 2 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 CCDC144C PF14915.6 EST41827.1 - 0.28 10.3 23.9 0.63 9.1 11.6 2.2 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region CALM_bind PF16025.5 EST41827.1 - 9.5 6.8 13.8 6.7 7.3 1.6 2.2 2 0 0 2 2 2 0 Calcium-dependent calmodulin binding Aa_trans PF01490.18 EST41828.1 - 2.4e-30 105.6 33.0 3.4e-30 105.1 33.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ceramidase PF05875.12 EST41828.1 - 0.035 13.5 6.2 0.087 12.2 1.5 3.2 2 1 0 2 2 2 0 Ceramidase ANAPC4_WD40 PF12894.7 EST41829.1 - 5.6e-05 23.4 0.1 0.00076 19.7 0.1 2.9 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Hormone_recep PF00104.30 EST41829.1 - 0.0054 16.3 0.2 0.014 14.9 0.2 1.7 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor TPR_19 PF14559.6 EST41829.1 - 0.0078 16.7 7.4 39 4.9 0.1 6.8 5 1 0 5 5 5 0 Tetratricopeptide repeat DUF836 PF05768.14 EST41829.1 - 0.021 15.2 2.8 0.026 14.9 0.1 2.7 3 0 0 3 3 3 0 Glutaredoxin-like domain (DUF836) TPR_12 PF13424.6 EST41829.1 - 0.026 14.8 6.8 47 4.4 0.1 6.1 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 EST41829.1 - 0.033 14.3 0.3 0.033 14.3 0.3 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF4945 PF16303.5 EST41829.1 - 0.11 12.4 0.1 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4945) TPR_1 PF00515.28 EST41829.1 - 1.7 8.6 6.4 4.3 7.3 0.3 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat FSH1 PF03959.13 EST41830.1 - 5.2e-24 85.1 0.1 1.4e-23 83.7 0.1 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 EST41830.1 - 0.0013 19.4 0.0 0.0016 19.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 EST41830.1 - 0.034 14.0 0.1 0.14 11.9 0.1 2.1 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase DUF3703 PF12487.8 EST41831.1 - 0.043 13.7 0.9 0.1 12.4 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3703) Lip_prot_lig_C PF10437.9 EST41831.1 - 0.11 12.6 2.1 6.1 6.9 0.1 2.8 2 1 0 3 3 3 0 Bacterial lipoate protein ligase C-terminus Enkurin PF13864.6 EST41831.1 - 8.1 7.0 16.0 0.066 13.7 4.8 3.0 3 1 1 4 4 4 0 Calmodulin-binding DUF4407 PF14362.6 EST41832.1 - 2.1 7.6 31.6 0.084 12.2 6.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Chordopox_A35R PF05989.12 EST41833.1 - 0.054 13.4 5.6 0.29 11.0 0.1 2.8 3 0 0 3 3 3 0 Chordopoxvirus A35R protein DUF3949 PF13133.6 EST41833.1 - 0.66 10.5 7.9 5 7.7 1.4 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3949) DSPc PF00782.20 EST41836.1 - 6.1e-10 39.0 0.0 1.3e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EST41836.1 - 2.8e-05 24.3 0.0 5.9e-05 23.2 0.0 1.5 2 0 0 2 2 2 1 Inositol hexakisphosphate DSPn PF14671.6 EST41836.1 - 0.00015 22.2 0.0 0.00032 21.2 0.0 1.5 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half Y_phosphatase PF00102.27 EST41836.1 - 0.00058 19.5 0.0 0.00084 19.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EST41836.1 - 0.074 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family CDKN3 PF05706.12 EST41836.1 - 0.15 11.7 0.0 0.6 9.8 0.0 1.9 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Pkinase PF00069.25 EST41839.1 - 0.00042 19.8 2.5 0.00042 19.8 2.5 2.5 2 1 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 EST41839.1 - 0.024 14.0 0.6 0.024 14.0 0.6 1.9 2 1 0 2 2 2 0 Kinase-like Pkinase_Tyr PF07714.17 EST41839.1 - 0.06 12.6 0.4 0.17 11.2 0.0 1.9 2 1 1 3 3 3 0 Protein tyrosine kinase HIP1_clath_bdg PF16515.5 EST41840.1 - 0.88 10.2 5.9 13 6.5 1.0 2.7 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Aa_trans PF01490.18 EST41841.1 - 2.2e-24 86.0 33.1 2.2e-24 86.0 33.1 1.7 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein DUF5305 PF17231.2 EST41841.1 - 0.05 13.0 3.5 6.1 6.2 0.1 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5305) ETRAMP PF09716.10 EST41841.1 - 8.3 6.6 7.2 7.1 6.8 0.4 3.5 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Shugoshin_N PF07558.11 EST41843.1 - 0.018 14.9 3.0 0.035 14.0 1.1 2.7 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DUF1843 PF08898.10 EST41843.1 - 0.044 14.3 3.0 0.044 14.3 3.0 3.6 2 2 2 4 4 4 0 Domain of unknown function (DUF1843) Csm1_N PF18504.1 EST41843.1 - 0.35 11.2 20.6 3.9 7.9 8.8 3.1 1 1 1 2 2 2 0 Csm1 N-terminal domain DUF724 PF05266.14 EST41843.1 - 0.82 9.5 11.0 1.2 8.9 11.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) COG2 PF06148.11 EST41843.1 - 1.1 9.3 16.6 0.21 11.7 8.0 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TMF_DNA_bd PF12329.8 EST41843.1 - 1.4 9.0 22.3 0.73 9.9 14.1 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4407 PF14362.6 EST41843.1 - 1.7 7.9 11.4 2.5 7.4 11.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LRS4 PF10422.9 EST41843.1 - 1.7 8.1 13.3 2 7.9 13.3 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 CEP19 PF14933.6 EST41843.1 - 2.6 8.4 10.7 3.1 8.1 10.7 1.1 1 0 0 1 1 1 0 CEP19-like protein MutS_III PF05192.18 EST41843.1 - 4.1 7.6 7.5 5.2 7.2 7.5 1.1 1 0 0 1 1 1 0 MutS domain III Spc29 PF17082.5 EST41843.1 - 5.8 6.7 11.8 0.96 9.2 4.9 2.0 1 1 1 2 2 2 0 Spindle Pole Component 29 FUSC PF04632.12 EST41843.1 - 7.4 5.0 5.5 8.1 4.8 5.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Metallophos PF00149.28 EST41844.1 - 6.4e-37 128.0 0.1 1.1e-36 127.2 0.0 1.4 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EST41844.1 - 0.0023 18.1 0.0 0.0042 17.3 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain BNIP2 PF12496.8 EST41845.1 - 1.8 9.0 12.0 8.1 6.9 1.2 3.9 3 0 0 3 3 3 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Myb_DNA-binding PF00249.31 EST41846.1 - 6.6e-18 64.6 1.8 1.7e-11 44.2 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST41846.1 - 7e-14 51.8 5.9 3.2e-07 30.5 1.4 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EST41846.1 - 2e-05 24.6 0.5 0.19 11.8 0.2 2.4 1 1 0 2 2 2 2 SLIDE AbbA_antirepres PF14156.6 EST41846.1 - 0.0046 16.8 0.4 0.099 12.5 0.1 2.4 2 0 0 2 2 2 1 Antirepressor AbbA Myb_DNA-bind_3 PF12776.7 EST41846.1 - 0.0089 17.0 4.2 0.75 10.8 0.8 3.0 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain PP_M1 PF03012.14 EST41846.1 - 0.013 15.1 0.2 0.017 14.7 0.2 1.2 1 0 0 1 1 1 0 Phosphoprotein FliG_C PF01706.16 EST41846.1 - 0.034 14.3 0.3 0.43 10.8 0.0 2.1 1 1 1 2 2 2 0 FliG C-terminal domain Rap1_C PF11626.8 EST41846.1 - 0.035 14.2 1.2 3 8.0 0.1 2.3 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Memo PF01875.17 EST41846.1 - 0.12 11.5 0.2 1.1 8.3 0.3 1.9 1 1 1 2 2 2 0 Memo-like protein Myb_DNA-bind_5 PF13873.6 EST41846.1 - 0.3 11.2 7.0 4.5 7.4 0.3 3.5 1 1 3 4 4 4 0 Myb/SANT-like DNA-binding domain DUP PF00674.18 EST41846.1 - 0.71 10.0 5.8 16 5.7 0.1 2.9 2 1 1 3 3 3 0 DUP family Atg29_N PF18388.1 EST41846.1 - 5.7 6.8 9.6 3.1 7.7 2.3 2.9 3 0 0 3 3 3 0 Atg29 N-terminal domain ARTD15_N PF18084.1 EST41847.1 - 0.12 12.6 0.8 1.2 9.4 0.8 2.3 1 1 0 1 1 1 0 ARTD15 N-terminal domain Ank_2 PF12796.7 EST41849.1 - 1.9e-18 66.8 5.8 5.6e-06 26.9 0.1 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EST41849.1 - 8.8e-14 50.3 1.8 0.048 14.2 0.0 6.6 7 0 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 EST41849.1 - 6.6e-11 42.2 0.3 0.0065 16.9 0.0 5.1 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 EST41849.1 - 4.7e-10 39.5 1.2 0.0012 19.1 0.0 4.2 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EST41849.1 - 5.3e-10 39.6 5.9 2.7e-06 27.8 0.0 4.2 4 1 1 5 5 5 3 Ankyrin repeats (many copies) DUF3624 PF12292.8 EST41850.1 - 0.013 15.9 1.1 0.013 15.9 1.1 3.8 3 2 1 4 4 4 0 Protein of unknown function (DUF3624) Sugar_tr PF00083.24 EST41851.1 - 2.5e-49 168.3 44.4 8.7e-32 110.6 16.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EST41851.1 - 3.8e-23 82.0 53.5 1.5e-19 70.1 35.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EST41851.1 - 6.3e-05 22.4 14.9 0.00012 21.6 14.9 1.5 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB RNR_Alpha PF17975.1 EST41852.1 - 0.007 16.8 0.7 0.029 14.8 0.1 2.0 2 1 0 2 2 2 1 Ribonucleotide reductase alpha domain CBFB_NFYA PF02045.15 EST41852.1 - 6.9 7.4 8.8 0.16 12.6 0.7 2.2 2 1 0 2 2 2 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B tRNA-synt_1d PF00750.19 EST41853.1 - 2.5e-119 398.3 0.4 3.6e-119 397.8 0.4 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EST41853.1 - 1.5e-21 76.8 0.4 4.1e-21 75.4 0.1 1.9 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 EST41853.1 - 1.1e-08 35.5 0.1 3.3e-08 34.0 0.1 1.8 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1g PF09334.11 EST41853.1 - 0.023 13.4 0.0 0.035 12.8 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EST41853.1 - 0.024 12.9 0.0 0.042 12.1 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 EST41853.1 - 0.087 12.2 0.5 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain STAS PF01740.21 EST41855.1 - 0.00013 21.6 0.1 0.00016 21.3 0.1 1.2 1 0 0 1 1 1 1 STAS domain ESCRT-II PF05871.12 EST41855.1 - 0.071 13.4 1.3 0.14 12.4 1.3 1.7 1 1 0 1 1 1 0 ESCRT-II complex subunit A2M_BRD PF07703.14 EST41856.1 - 0.0082 16.5 0.2 0.011 16.0 0.2 1.4 1 0 0 1 1 1 1 Alpha-2-macroglobulin bait region domain KicB PF03882.14 EST41857.1 - 0.037 14.2 3.5 0.046 13.9 3.5 1.2 1 0 0 1 1 1 0 MukF winged-helix domain DHR10 PF18595.1 EST41857.1 - 0.054 13.6 25.1 0.29 11.2 1.4 2.7 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain Serine_rich PF08824.10 EST41857.1 - 0.06 13.3 11.4 0.034 14.2 7.4 1.9 1 1 1 2 2 2 0 Serine rich protein interaction domain FKBP_N PF01346.18 EST41857.1 - 0.44 11.5 16.3 0.45 11.5 14.3 1.9 1 1 1 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase FPP PF05911.11 EST41857.1 - 0.53 8.4 24.4 0.6 8.2 24.4 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DUF1910 PF08928.10 EST41857.1 - 0.81 9.7 14.3 1.6 8.7 0.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1910) PRKG1_interact PF15898.5 EST41857.1 - 1.1 10.2 21.8 4.3 8.3 12.8 2.1 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain FapA PF03961.13 EST41857.1 - 1.1 7.7 18.2 1.3 7.6 18.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A GrpE PF01025.19 EST41857.1 - 2.7 7.6 18.3 2.3e+02 1.3 18.3 2.1 1 1 0 1 1 1 0 GrpE E2F_CC-MB PF16421.5 EST41857.1 - 2.7 8.4 20.2 1.6 9.1 4.1 2.2 1 1 1 2 2 2 0 E2F transcription factor CC-MB domain Atg14 PF10186.9 EST41857.1 - 2.9 6.9 20.8 5.8 5.9 20.8 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 LPP PF04728.13 EST41857.1 - 3.5 8.1 13.3 2.2 8.7 1.8 2.9 2 1 1 3 3 3 0 Lipoprotein leucine-zipper DUF4279 PF14106.6 EST41857.1 - 4.4 7.6 10.1 8 6.7 3.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4279) SH3_13 PF18335.1 EST41857.1 - 4.4 7.2 7.8 0.84 9.5 3.9 1.8 2 0 0 2 2 2 0 ATP-dependent RecD-like DNA helicase SH3 domain GvpL_GvpF PF06386.11 EST41857.1 - 4.9 7.0 10.7 3.1 7.7 8.4 1.4 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF ACR_tran PF00873.19 EST41857.1 - 5.2 4.6 10.0 6 4.4 10.0 1.0 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family GIDA_assoc PF13932.6 EST41857.1 - 6.1 7.0 15.1 6.8 6.8 15.1 1.1 1 0 0 1 1 1 0 GidA associated domain DUF948 PF06103.11 EST41857.1 - 6.3 7.1 9.1 4.6e+02 1.2 8.9 2.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) COG2 PF06148.11 EST41857.1 - 6.8 6.8 15.7 4.6 7.3 9.4 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.12 EST41857.1 - 8.6 6.4 15.7 16 5.5 12.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Peptidase_A6 PF01829.16 EST41859.1 - 0.06 12.7 0.1 0.067 12.5 0.1 1.1 1 0 0 1 1 1 0 Peptidase A6 family DUF4573 PF15140.6 EST41860.1 - 0.0089 15.8 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4573) LRR_4 PF12799.7 EST41861.1 - 0.034 14.6 26.2 1.8 9.1 1.2 5.4 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) ERCC4 PF02732.15 EST41862.1 - 2.1e-07 31.2 1.1 1e-06 29.0 0.1 2.3 2 1 0 2 2 2 1 ERCC4 domain PocR PF10114.9 EST41862.1 - 0.08 12.7 0.3 0.29 10.9 0.1 1.9 1 1 1 2 2 2 0 Sensory domain found in PocR DUF1878 PF08963.10 EST41862.1 - 0.24 11.9 5.0 0.25 11.8 1.1 2.5 2 1 0 3 3 3 0 Protein of unknown function (DUF1878) ATP_bind_3 PF01171.20 EST41863.1 - 4.1e-20 72.3 0.0 6e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 PP-loop family PAPS_reduct PF01507.19 EST41863.1 - 0.0053 16.8 0.1 0.022 14.8 0.1 1.9 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family QueC PF06508.13 EST41863.1 - 0.057 12.9 0.1 3.4 7.1 0.1 2.4 1 1 0 1 1 1 0 Queuosine biosynthesis protein QueC UDPGP PF01704.18 EST41864.1 - 3.5e-09 35.8 8.9 8.5e-09 34.5 8.9 1.5 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 EST41864.1 - 7e-05 23.2 0.0 0.00014 22.2 0.0 1.4 1 1 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 EST41864.1 - 0.086 12.4 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyl transferase Aa_trans PF01490.18 EST41865.1 - 5.2e-34 117.7 44.9 9.2e-34 116.8 44.9 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Pkinase PF00069.25 EST41867.1 - 1.2e-52 178.9 0.0 1.4e-52 178.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST41867.1 - 1.2e-20 73.9 0.0 2.2e-20 73.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EST41867.1 - 0.00091 18.6 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EST41867.1 - 0.0078 15.6 0.0 0.017 14.4 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EST41867.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Phospholip_B PF04916.13 EST41868.1 - 8.3e-113 377.8 4.2 9.8e-113 377.5 4.2 1.0 1 0 0 1 1 1 1 Phospholipase B Arf PF00025.21 EST41869.1 - 1.6e-57 193.8 0.0 1.7e-57 193.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EST41869.1 - 2.4e-11 43.4 0.0 3e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EST41869.1 - 1.3e-10 41.0 0.4 1.4e-06 27.7 0.0 2.5 2 1 0 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EST41869.1 - 4.3e-10 39.9 0.0 5.5e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EST41869.1 - 8.2e-08 32.3 0.0 1.1e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 EST41869.1 - 2.4e-07 30.5 0.0 2.9e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EST41869.1 - 8.2e-05 22.1 0.0 9.8e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 EST41869.1 - 0.014 15.9 0.0 0.016 15.7 0.0 1.5 1 1 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.27 EST41869.1 - 0.023 14.2 0.1 2.7 7.5 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 EST41869.1 - 0.13 12.0 0.0 0.39 10.4 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation GDH_N PF12466.8 EST41871.1 - 0.11 12.7 0.5 0.24 11.6 0.1 1.7 2 0 0 2 2 2 0 Glutamate dehydrogenase N terminal Spt4 PF06093.13 EST41872.1 - 0.0004 20.4 0.2 0.0013 18.8 0.2 1.8 1 1 0 1 1 1 1 Spt4/RpoE2 zinc finger TackOD1 PF18551.1 EST41872.1 - 0.0032 17.2 0.5 0.0042 16.8 0.5 1.1 1 0 0 1 1 1 1 Thaumarchaeal output domain 1 TBCC PF07986.12 EST41872.1 - 0.005 16.6 0.3 0.0065 16.2 0.3 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor C zf-RING_4 PF14570.6 EST41872.1 - 0.0052 16.6 2.5 0.0099 15.7 2.5 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain NRDD PF13597.6 EST41872.1 - 0.025 13.4 0.4 0.027 13.2 0.4 1.0 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase PADR1 PF08063.12 EST41872.1 - 0.027 14.3 0.6 0.045 13.5 0.6 1.4 1 0 0 1 1 1 0 PADR1 (NUC008) domain DUF35_N PF12172.8 EST41872.1 - 0.041 13.8 0.3 0.064 13.2 0.3 1.3 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-C4H2 PF10146.9 EST41872.1 - 0.15 12.4 0.5 0.2 12.0 0.5 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein DUF4174 PF13778.6 EST41874.1 - 0.042 14.3 0.1 0.15 12.6 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) ELMO_CED12 PF04727.13 EST41875.1 - 2.1e-13 50.8 0.0 3.5e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family Speriolin_C PF15059.6 EST41875.1 - 0.012 15.8 1.7 0.079 13.1 0.1 2.6 2 1 1 3 3 3 0 Speriolin C-terminus Hydrolase_4 PF12146.8 EST41876.1 - 3.3e-11 42.9 0.0 2.3e-06 27.0 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EST41876.1 - 6.1e-06 25.9 0.0 0.013 14.9 0.0 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EST41876.1 - 9.1e-06 25.5 0.9 0.026 14.1 0.1 2.5 1 1 1 2 2 2 2 alpha/beta hydrolase fold LIP PF03583.14 EST41876.1 - 0.00048 19.6 0.6 0.024 14.0 0.1 2.1 2 0 0 2 2 2 1 Secretory lipase Esterase PF00756.20 EST41876.1 - 0.013 15.2 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.16 EST41876.1 - 0.015 15.1 0.3 0.066 13.0 0.3 1.9 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase FSH1 PF03959.13 EST41876.1 - 0.017 14.8 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 EST41876.1 - 0.031 14.9 0.0 0.04 14.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Snf7 PF03357.21 EST41877.1 - 2.2e-11 43.7 32.7 2.8e-11 43.3 32.7 1.1 1 0 0 1 1 1 1 Snf7 L_biotic_typeA PF04604.13 EST41877.1 - 0.057 13.3 1.2 0.057 13.3 1.2 2.4 3 0 0 3 3 3 0 Type-A lantibiotic Flu_M1 PF00598.19 EST41877.1 - 0.088 12.3 1.9 3.6 7.1 0.4 2.1 1 1 1 2 2 2 0 Influenza Matrix protein (M1) Herpes_BLRF2 PF05812.12 EST41877.1 - 0.87 9.7 8.0 0.34 11.1 1.0 2.7 1 1 1 3 3 3 0 Herpesvirus BLRF2 protein bZIP_2 PF07716.15 EST41877.1 - 8.8 6.5 10.1 0.96 9.6 2.4 2.8 2 0 0 2 2 2 0 Basic region leucine zipper GDH_N PF12466.8 EST41878.1 - 0.1 12.8 0.5 0.21 11.8 0.1 1.6 2 0 0 2 2 2 0 Glutamate dehydrogenase N terminal ELMO_CED12 PF04727.13 EST41879.1 - 1.3e-13 51.4 0.2 1.8e-13 51.0 0.2 1.1 1 0 0 1 1 1 1 ELMO/CED-12 family Bromodomain PF00439.25 EST41880.1 - 5.4e-08 32.8 0.3 2.6e-07 30.6 0.3 2.2 1 0 0 1 1 1 1 Bromodomain WD40 PF00400.32 EST41880.1 - 0.12 13.3 0.1 0.12 13.3 0.1 2.4 2 0 0 2 2 2 0 WD domain, G-beta repeat Aa_trans PF01490.18 EST41882.1 - 3.3e-28 98.5 42.4 4.1e-28 98.2 42.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TPR_19 PF14559.6 EST41891.1 - 0.0025 18.3 0.0 0.49 10.9 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Fungal_TACC PF12709.7 EST41891.1 - 0.1 13.1 8.2 0.12 12.9 2.0 3.0 3 0 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins TPR_14 PF13428.6 EST41891.1 - 0.18 12.7 0.9 16 6.6 0.0 4.0 4 1 1 5 5 5 0 Tetratricopeptide repeat MCPVI PF02993.14 EST41892.1 - 0.064 13.1 0.3 0.11 12.3 0.3 1.4 1 0 0 1 1 1 0 Minor capsid protein VI Ras_bdg_2 PF14847.6 EST41894.1 - 0.01 16.1 0.5 0.016 15.6 0.5 1.4 1 0 0 1 1 1 0 Ras-binding domain of Byr2 Allantoicase PF03561.15 EST41894.1 - 0.043 13.8 0.7 0.067 13.2 0.5 1.3 1 1 0 1 1 1 0 Allantoicase repeat CLIP PF12032.8 EST41894.1 - 0.092 13.0 0.5 0.19 12.1 0.5 1.8 1 1 0 1 1 1 0 Regulatory CLIP domain of proteinases Ly-6_related PF06579.12 EST41894.1 - 0.1 12.9 0.6 0.15 12.3 0.4 1.4 1 1 0 1 1 1 0 Caenorhabditis elegans ly-6-related protein V_ATPase_I PF01496.19 EST41896.1 - 0.09 10.7 2.3 0.1 10.5 2.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0172 PF03665.13 EST41896.1 - 0.1 12.7 1.7 0.17 12.0 1.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) UPF0242 PF06785.11 EST41896.1 - 0.96 9.5 20.4 0.24 11.5 2.2 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Gp58 PF07902.11 EST41896.1 - 2.5 6.3 14.4 1.8 6.8 12.9 1.5 1 1 1 2 2 2 0 gp58-like protein FapA PF03961.13 EST41896.1 - 3.8 6.0 5.4 5.5 5.5 5.3 1.3 1 1 0 1 1 1 0 Flagellar Assembly Protein A Myb_DNA-bind_6 PF13921.6 EST41897.1 - 1.5e-10 41.1 4.4 1.4e-06 28.5 0.3 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EST41897.1 - 1.7e-10 40.9 0.4 1.5e-06 28.3 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST41897.1 - 0.1 12.5 0.7 0.18 11.7 0.2 1.7 2 0 0 2 2 2 0 Myb DNA-binding like Copine PF07002.16 EST41899.1 - 1.5e-09 37.7 0.3 3.6e-09 36.4 0.3 1.6 1 1 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 EST41899.1 - 1.5e-06 28.5 0.2 1.9e-06 28.1 0.2 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus I_LWEQ PF01608.17 EST41900.1 - 0.0073 16.6 12.1 0.0073 16.6 12.1 5.7 4 1 2 6 6 6 1 I/LWEQ domain TnpV PF14198.6 EST41900.1 - 0.042 13.8 0.5 0.042 13.8 0.5 4.5 6 1 1 7 7 7 0 Transposon-encoded protein TnpV CC2-LZ PF16516.5 EST41901.1 - 0.017 15.5 2.6 0.017 15.5 2.6 1.9 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Preseq_ALAS PF09029.10 EST41901.1 - 0.24 11.9 3.1 0.2 12.1 1.2 1.9 1 1 1 2 2 2 0 5-aminolevulinate synthase presequence CSN5_C PF18323.1 EST41901.1 - 0.64 11.0 5.0 0.96 10.4 3.3 2.2 2 1 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain DUF349 PF03993.12 EST41902.1 - 0.027 14.7 2.9 0.027 14.7 2.9 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Peptidase_S46 PF10459.9 EST41902.1 - 0.27 9.8 14.6 0.32 9.6 14.6 1.1 1 0 0 1 1 1 0 Peptidase S46 HAGH_C PF16123.5 EST41902.1 - 2.4 8.7 8.4 0.61 10.6 0.4 3.0 1 1 1 3 3 3 0 Hydroxyacylglutathione hydrolase C-terminus DUF4618 PF15397.6 EST41903.1 - 0.0028 17.1 5.6 0.0028 17.1 5.6 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4618) PUB PF09409.10 EST41903.1 - 0.046 13.7 0.8 0.16 12.0 0.8 2.0 1 1 0 1 1 1 0 PUB domain Matrilin_ccoil PF10393.9 EST41903.1 - 0.078 12.9 3.7 1.5 8.7 0.0 3.1 3 1 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Mod_r PF07200.13 EST41903.1 - 0.19 11.9 7.8 0.38 10.8 7.8 1.5 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Laminin_II PF06009.12 EST41903.1 - 0.22 11.5 5.9 0.28 11.2 4.9 1.7 1 1 0 1 1 1 0 Laminin Domain II NPV_P10 PF05531.12 EST41903.1 - 0.88 10.1 10.3 0.21 12.1 5.8 2.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 EST41903.1 - 0.94 9.5 4.5 1 9.4 3.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) zf-met PF12874.7 EST41908.1 - 4.9e-05 23.6 2.0 8.9e-05 22.7 2.0 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CpXC PF14353.6 EST41908.1 - 0.00019 21.5 0.2 0.00023 21.2 0.2 1.1 1 0 0 1 1 1 1 CpXC protein zf-C2H2_2 PF12756.7 EST41908.1 - 0.0073 16.6 4.9 0.0094 16.3 4.9 1.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 EST41908.1 - 0.019 15.3 4.8 0.038 14.3 4.8 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding NADHdh_A3 PF14987.6 EST41909.1 - 4.7 7.6 6.1 0.55 10.6 0.4 2.0 2 1 0 2 2 2 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 RRP36 PF06102.12 EST41910.1 - 2.7e-18 66.5 19.8 3e-18 66.3 19.8 1.0 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 Myb_DNA-bind_7 PF15963.5 EST41911.1 - 1.2e-05 25.1 4.2 3.9e-05 23.5 0.0 3.2 2 1 2 4 4 4 1 Myb DNA-binding like ubiquitin PF00240.23 EST41912.1 - 4.2e-34 116.1 0.6 4.6e-34 116.0 0.6 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EST41912.1 - 1.1e-18 66.8 0.9 1.2e-18 66.7 0.9 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EST41912.1 - 5.6e-06 26.7 0.2 2.3e-05 24.7 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EST41912.1 - 7.3e-05 22.8 0.1 0.00014 21.9 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 EST41912.1 - 0.0004 20.3 0.1 0.00045 20.1 0.1 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 EST41912.1 - 0.00056 20.4 0.1 0.00065 20.2 0.1 1.1 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 EST41912.1 - 0.00065 19.7 0.8 0.69 10.0 0.1 2.0 1 1 1 2 2 2 2 Ubiquitin-like domain Ubiquitin_5 PF18037.1 EST41912.1 - 0.0013 19.0 0.1 0.0014 18.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain Sde2_N_Ubi PF13019.6 EST41912.1 - 0.017 14.9 0.0 0.019 14.8 0.0 1.0 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain Ank_2 PF12796.7 EST41914.1 - 9.2e-09 35.8 1.1 0.0001 22.8 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EST41914.1 - 5.8e-05 23.6 0.4 0.72 10.5 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EST41914.1 - 6e-05 23.3 1.2 0.13 12.8 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 EST41914.1 - 0.00016 21.9 0.2 1.4 9.8 0.0 4.0 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 EST41914.1 - 0.00097 19.4 1.7 4.1 7.8 0.0 3.6 3 1 1 4 4 4 2 Ankyrin repeats (many copies) PMC2NT PF08066.12 EST41915.1 - 0.0072 17.0 0.2 0.013 16.2 0.2 1.4 1 0 0 1 1 1 1 PMC2NT (NUC016) domain Plasmo_rep PF12135.8 EST41915.1 - 0.041 13.4 0.0 0.093 12.3 0.0 1.6 1 0 0 1 1 1 0 Plasmodium repeat family DUF4064 PF13273.6 EST41917.1 - 0.0052 17.0 0.0 0.0065 16.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) TraL PF07178.11 EST41917.1 - 0.0057 17.1 0.1 0.0082 16.6 0.1 1.1 1 0 0 1 1 1 1 TraL protein Chordopox_A13L PF05961.11 EST41917.1 - 0.0064 16.7 0.1 0.011 16.0 0.1 1.5 1 0 0 1 1 1 1 Chordopoxvirus A13L protein DUF515 PF04415.12 EST41917.1 - 0.012 14.0 1.3 0.014 13.8 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF5305 PF17231.2 EST41917.1 - 0.012 15.0 0.0 0.014 14.8 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) OAD_gamma PF04277.13 EST41917.1 - 0.025 15.2 0.0 0.032 14.8 0.0 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF4271 PF14093.6 EST41917.1 - 0.031 14.2 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) Saf_2TM PF18303.1 EST41917.1 - 0.068 12.8 0.0 0.079 12.5 0.0 1.2 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain Myc_target_1 PF15179.6 EST41917.1 - 0.073 13.0 0.0 0.083 12.8 0.0 1.2 1 0 0 1 1 1 0 Myc target protein 1 ETRAMP PF09716.10 EST41917.1 - 0.71 10.0 6.5 1.7 8.8 6.5 1.8 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) CYYR1 PF10873.8 EST41917.1 - 1.8 9.0 4.7 2.3 8.7 4.7 1.3 1 1 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 MatE PF01554.18 EST41918.1 - 4.2e-28 98.0 31.8 3.3e-18 65.8 11.2 2.8 3 1 0 3 3 3 2 MatE Gp5_OB PF06714.11 EST41918.1 - 0.074 13.3 0.1 9.9 6.4 0.0 2.5 2 0 0 2 2 2 0 Gp5 N-terminal OB domain Polysacc_synt_C PF14667.6 EST41918.1 - 0.4 10.7 35.8 0.036 14.1 13.1 4.6 3 2 0 3 3 3 0 Polysaccharide biosynthesis C-terminal domain zf-C2H2 PF00096.26 EST41919.1 - 2.2e-18 65.6 33.0 9e-05 22.7 0.1 5.1 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EST41919.1 - 2e-17 62.3 32.0 0.00037 21.1 0.2 5.1 5 0 0 5 5 5 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EST41919.1 - 3e-14 52.7 32.2 1.5e-05 25.2 0.1 6.2 6 0 0 6 6 6 3 Zinc-finger double domain zf-met PF12874.7 EST41919.1 - 1.3e-10 41.3 20.6 0.002 18.4 2.6 4.4 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EST41919.1 - 2.4e-06 27.7 22.6 0.0051 17.1 0.1 4.7 5 1 0 5 5 4 3 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 EST41919.1 - 7.4e-05 22.4 23.3 0.38 10.6 0.1 5.5 5 0 0 5 5 5 4 C2H2-type zinc-finger domain zf-Di19 PF05605.12 EST41919.1 - 8.8e-05 22.7 24.7 0.014 15.7 5.8 3.9 2 1 2 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 EST41919.1 - 0.02 15.2 26.3 1.1 9.6 0.3 4.6 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 EST41919.1 - 0.031 14.3 0.0 0.031 14.3 0.0 5.5 5 1 0 5 5 5 0 C2H2-type zinc finger BolA PF01722.18 EST41919.1 - 0.039 14.2 4.3 1.9 8.8 1.7 2.9 1 1 1 2 2 2 0 BolA-like protein zf-Sec23_Sec24 PF04810.15 EST41919.1 - 0.11 12.6 20.7 1.5 9.0 0.4 4.8 3 1 1 4 4 4 0 Sec23/Sec24 zinc finger LIM PF00412.22 EST41919.1 - 0.38 11.0 20.9 5.2 7.4 7.6 3.9 2 2 1 3 3 3 0 LIM domain zf-nanos PF05741.13 EST41919.1 - 0.58 10.4 22.2 2.6 8.3 0.7 4.3 2 1 2 4 4 4 0 Nanos RNA binding domain PriA_CRR PF18319.1 EST41919.1 - 0.76 9.8 0.1 0.76 9.8 0.1 5.3 6 1 1 7 7 6 0 PriA DNA helicase Cys-rich region (CRR) domain zf-MYST PF17772.1 EST41919.1 - 0.86 9.3 22.5 2.1 8.0 1.6 4.4 1 1 3 4 4 4 0 MYST family zinc finger domain GAGA PF09237.11 EST41919.1 - 1 9.2 13.2 0.64 9.9 0.5 3.4 3 1 0 3 3 3 0 GAGA factor Rpr2 PF04032.16 EST41919.1 - 1.3 9.4 10.9 1.4 9.3 3.9 2.4 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf_UBZ PF18439.1 EST41919.1 - 2.2 8.0 16.5 3.7 7.2 0.2 4.3 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Zn_ribbon_SprT PF17283.2 EST41919.1 - 2.5 8.1 17.7 0.66 9.9 0.9 4.0 2 1 1 3 3 3 0 SprT-like zinc ribbon domain zf-C2H2_9 PF16293.5 EST41919.1 - 2.5 8.0 19.3 18 5.3 0.3 4.9 3 2 2 5 5 5 0 C2H2 type zinc-finger (1 copy) PHD PF00628.29 EST41919.1 - 3.4 7.6 18.7 0.18 11.8 3.5 3.7 4 0 0 4 4 4 0 PHD-finger zf-BED PF02892.15 EST41919.1 - 6 7.0 19.4 20 5.3 0.1 4.2 1 1 2 3 3 3 0 BED zinc finger Methyltransf_16 PF10294.9 EST41920.1 - 1.9e-14 53.8 0.0 2.5e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 EST41920.1 - 8.8e-08 31.9 0.0 1.1e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 EST41920.1 - 2e-05 24.5 0.1 3e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EST41920.1 - 2.5e-05 24.9 0.0 5.9e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EST41920.1 - 0.0004 20.0 0.0 0.00062 19.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 EST41920.1 - 0.0022 18.6 0.0 0.0035 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EST41920.1 - 0.0062 17.3 0.0 0.01 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MFS_1 PF07690.16 EST41921.1 - 7.4e-22 77.7 36.0 9.7e-22 77.4 34.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Myb_DNA-bind_7 PF15963.5 EST41922.1 - 6.7e-06 25.9 2.3 0.00013 21.7 0.0 3.1 1 1 3 4 4 4 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 EST41922.1 - 0.05 13.8 0.0 0.33 11.2 0.0 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain DUF725 PF05267.12 EST41923.1 - 0.16 12.0 0.0 0.2 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF725) Hexapep_2 PF14602.6 EST41925.1 - 2.1e-12 46.6 10.0 1.4e-10 40.7 3.3 3.3 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 EST41925.1 - 7.2e-12 44.5 6.1 8.5e-10 38.0 3.9 2.8 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 EST41925.1 - 0.00059 20.0 0.0 0.0009 19.4 0.0 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase LRR_4 PF12799.7 EST41926.1 - 3e-10 40.2 18.1 1.8e-05 25.0 1.1 4.1 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EST41926.1 - 1.8e-07 30.8 14.1 0.0036 17.0 0.7 3.7 1 1 3 4 4 4 4 Leucine rich repeat LRR_6 PF13516.6 EST41926.1 - 2.5e-06 27.1 10.8 0.16 12.1 0.0 5.7 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.33 EST41926.1 - 0.00043 20.4 11.8 4.3 8.3 0.1 5.9 5 0 0 5 5 5 3 Leucine Rich Repeat DUF3511 PF12023.8 EST41927.1 - 0.072 12.9 0.2 0.13 12.1 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3511) RabGAP-TBC PF00566.18 EST41929.1 - 1.6e-33 116.1 3.1 2.9e-33 115.4 3.1 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Lipoprotein_17 PF04200.12 EST41929.1 - 0.019 15.3 1.0 0.019 15.3 1.0 2.8 3 0 0 3 3 3 0 Lipoprotein associated domain Tsi6 PF18660.1 EST41930.1 - 0.14 12.2 0.5 1.2 9.2 0.1 2.3 2 0 0 2 2 2 0 Tsi6 Tctex-1 PF03645.13 EST41931.1 - 3.7e-17 62.4 0.6 4.7e-17 62.1 0.6 1.1 1 0 0 1 1 1 1 Tctex-1 family DUF4403 PF14356.6 EST41931.1 - 0.049 12.3 0.1 0.065 11.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4403) RP-C_C PF11800.8 EST41932.1 - 0.3 11.2 3.9 0.38 10.8 3.9 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Alpha_adaptinC2 PF02883.20 EST41935.1 - 0.067 13.5 0.3 0.28 11.5 0.3 1.9 1 1 0 1 1 1 0 Adaptin C-terminal domain bMG1 PF17970.1 EST41936.1 - 0.11 12.5 0.1 0.22 11.6 0.0 1.4 1 1 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG1 domain UPF0047 PF01894.17 EST41937.1 - 2.2e-34 118.1 0.0 2.5e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 DUF4498 PF14926.6 EST41938.1 - 1.6e-29 103.0 0.1 1.8e-29 102.8 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4498) Furin-like_2 PF15913.5 EST41939.1 - 0.069 13.3 11.4 0.096 12.9 11.4 1.2 1 0 0 1 1 1 0 Furin-like repeat, cysteine-rich zf-P11 PF03854.14 EST41939.1 - 0.44 10.2 6.8 0.82 9.4 6.8 1.4 1 0 0 1 1 1 0 P-11 zinc finger Ribosomal_L21e PF01157.18 EST41941.1 - 5.1e-17 61.6 1.3 8.7e-17 60.8 1.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L21e DUF3945 PF13101.6 EST41941.1 - 0.062 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3945) Ribosomal_L21e PF01157.18 EST41945.1 - 4.7e-39 132.3 2.9 7.2e-39 131.7 2.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e AIG2_2 PF13772.6 EST41945.1 - 0.08 13.3 0.0 0.23 11.9 0.0 1.8 1 0 0 1 1 1 0 AIG2-like family Nuf2 PF03800.14 EST41946.1 - 2.9e-30 105.2 5.2 2.9e-30 105.2 5.2 2.6 2 1 1 3 3 3 1 Nuf2 family TPR_MLP1_2 PF07926.12 EST41946.1 - 0.13 12.3 35.9 0.51 10.4 5.6 3.6 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein Filament PF00038.21 EST41946.1 - 0.84 9.2 32.5 4.7 6.7 32.5 2.3 1 1 0 1 1 1 0 Intermediate filament protein Spc7 PF08317.11 EST41946.1 - 1.6 7.5 41.6 3.3 6.5 20.2 3.5 1 1 3 4 4 4 0 Spc7 kinetochore protein Thioredoxin_8 PF13905.6 EST41946.1 - 1.7 9.0 5.6 0.49 10.8 1.5 2.3 2 1 0 2 2 2 0 Thioredoxin-like DUF2206 PF09971.9 EST41947.1 - 0.35 9.6 0.9 0.41 9.4 0.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) Furin-like_2 PF15913.5 EST41948.1 - 0.00049 20.2 8.6 0.00063 19.9 8.6 1.2 1 0 0 1 1 1 1 Furin-like repeat, cysteine-rich DUF3149 PF11346.8 EST41948.1 - 0.0078 15.8 1.0 0.013 15.1 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3149) JAMP PF05571.12 EST41948.1 - 0.022 14.4 1.6 0.034 13.8 1.6 1.5 1 1 0 1 1 1 0 JNK1/MAPK8-associated membrane protein DAG1 PF05454.11 EST41948.1 - 0.034 13.5 0.1 0.034 13.5 0.1 1.1 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF5385 PF17359.2 EST41948.1 - 0.043 13.4 0.3 0.056 13.0 0.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5385) DUF3404 PF11884.8 EST41948.1 - 0.092 11.9 1.2 0.1 11.8 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3404) EphA2_TM PF14575.6 EST41948.1 - 0.11 13.3 0.2 0.27 12.1 0.1 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain NRBF2_MIT PF17169.4 EST41949.1 - 0.49 10.7 1.7 1.4 9.2 0.0 2.7 3 0 0 3 3 3 0 MIT domain of nuclear receptor-binding factor 2 SR-25 PF10500.9 EST41949.1 - 3 7.4 8.1 6.2 6.4 8.1 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3792 PF12670.7 EST41950.1 - 0.0083 16.3 0.2 0.011 15.9 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3792) EphA2_TM PF14575.6 EST41950.1 - 0.017 16.0 0.2 0.028 15.3 0.2 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 EST41950.1 - 0.041 14.2 0.1 0.047 14.0 0.1 1.1 1 0 0 1 1 1 0 Orf78 (ac78) TMEM154 PF15102.6 EST41950.1 - 0.049 13.5 0.1 0.049 13.5 0.1 1.2 1 0 0 1 1 1 0 TMEM154 protein family Protocadherin PF08374.11 EST41950.1 - 0.071 13.1 0.1 0.079 12.9 0.1 1.2 1 0 0 1 1 1 0 Protocadherin Cadherin_C_2 PF16492.5 EST41950.1 - 0.14 12.9 0.7 0.19 12.5 0.1 1.5 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal PolC_DP2 PF03833.13 EST41950.1 - 0.23 9.3 3.1 0.21 9.4 3.1 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 VSP PF03302.13 EST41950.1 - 0.27 10.1 11.7 0.7 8.7 11.8 1.5 1 1 1 2 2 2 0 Giardia variant-specific surface protein zinc_ribbon_4 PF13717.6 EST41950.1 - 3.3 7.7 9.5 4 7.5 2.9 3.1 2 1 1 3 3 3 0 zinc-ribbon domain Furin-like_2 PF15913.5 EST41951.1 - 0.092 12.9 7.4 0.21 11.8 7.4 1.6 1 1 0 1 1 1 0 Furin-like repeat, cysteine-rich TMEMspv1-c74-12 PF11044.8 EST41951.1 - 1.5 8.9 5.6 2.1 8.4 5.2 1.6 1 1 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Laminin_EGF PF00053.24 EST41951.1 - 3.7 7.8 12.1 23 5.2 12.1 2.4 1 1 0 1 1 1 0 Laminin EGF domain tRNA_int_endo PF01974.17 EST41952.1 - 3.5e-11 43.0 0.8 5.9e-11 42.3 0.8 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Snf7 PF03357.21 EST41953.1 - 0.046 13.3 4.3 0.041 13.5 2.3 2.0 2 0 0 2 2 2 0 Snf7 KTI12 PF08433.10 EST41954.1 - 8.5e-31 107.4 3.1 1.5e-30 106.6 3.1 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 EST41954.1 - 0.00019 21.6 0.0 0.00038 20.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EST41954.1 - 0.057 14.0 0.1 0.19 12.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EST41954.1 - 0.077 13.4 0.0 0.25 11.7 0.0 2.0 1 1 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 EST41954.1 - 0.098 12.6 0.0 0.28 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 EST41954.1 - 0.12 12.8 0.1 0.55 10.7 0.0 2.1 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) MatE PF01554.18 EST41955.1 - 9.2e-32 109.9 28.7 1.5e-19 70.2 10.3 2.5 2 1 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 EST41955.1 - 9.4e-05 22.5 7.5 9.4e-05 22.5 7.5 4.5 4 1 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Polysacc_synt PF01943.17 EST41955.1 - 0.0005 19.5 13.7 0.0005 19.5 13.7 3.1 1 1 1 3 3 3 2 Polysaccharide biosynthesis protein Osw5 PF17062.5 EST41955.1 - 0.057 13.5 9.7 1.6 8.9 0.0 3.7 3 0 0 3 3 3 0 Outer spore wall 5 BTAD PF03704.17 EST41956.1 - 0.021 15.2 0.1 0.036 14.5 0.1 1.4 1 0 0 1 1 1 0 Bacterial transcriptional activator domain Dioxygenase_N PF04444.14 EST41957.1 - 0.07 13.0 0.1 0.16 11.8 0.0 1.6 2 0 0 2 2 2 0 Catechol dioxygenase N terminus zf-RING_2 PF13639.6 EST41959.1 - 0.002 18.4 3.3 0.002 18.4 3.3 3.8 4 1 0 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.25 EST41959.1 - 0.0041 16.9 3.9 0.0041 16.9 3.9 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) SF3a60_bindingd PF12108.8 EST41962.1 - 0.19 11.7 1.3 9.5 6.2 0.1 2.5 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain DUF3147 PF11345.8 EST41968.1 - 0.00051 20.4 0.6 0.00086 19.7 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3147) Glycophorin_A PF01102.18 EST41968.1 - 0.092 13.0 0.1 0.15 12.3 0.1 1.3 1 0 0 1 1 1 0 Glycophorin A EphA2_TM PF14575.6 EST41968.1 - 0.16 12.9 2.0 0.35 11.8 2.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3149 PF11346.8 EST41968.1 - 0.33 10.6 4.2 0.56 9.9 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Thioredoxin PF00085.20 EST41970.1 - 4.1e-25 87.7 0.3 1.9e-24 85.6 0.1 1.9 2 0 0 2 2 2 1 Thioredoxin OST3_OST6 PF04756.13 EST41970.1 - 6.7e-07 28.9 0.0 8.4e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EST41970.1 - 5.1e-06 26.7 0.0 1.7e-05 25.0 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EST41970.1 - 4.5e-05 23.9 0.1 9.9e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 EST41970.1 - 0.0003 20.7 0.1 0.0005 20.0 0.1 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 EST41970.1 - 0.018 14.8 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Pkinase PF00069.25 EST41971.1 - 8.8e-44 149.8 0.1 1.5e-43 149.1 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST41971.1 - 7.7e-30 104.0 0.4 1.2e-28 100.1 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EST41971.1 - 8e-05 22.1 0.4 0.00015 21.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EST41971.1 - 0.00086 18.2 0.0 0.0015 17.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EST41971.1 - 0.05 13.5 0.0 0.078 12.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EST41971.1 - 0.056 12.8 1.8 0.15 11.4 0.2 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Gp-FAR-1 PF05823.12 EST41971.1 - 0.063 13.6 2.0 0.069 13.5 0.1 2.0 3 0 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) MRP-S23 PF10484.9 EST41972.1 - 0.032 14.5 2.4 0.053 13.8 2.4 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein S23 His_Phos_1 PF00300.22 EST41974.1 - 1.2e-43 149.1 0.0 1.3e-43 149.0 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF2967 PF11179.8 EST41975.1 - 0.34 9.0 1.2 0.35 8.9 1.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) AAA_6 PF12774.7 EST41976.1 - 1.7e-133 444.7 6.2 1.4e-132 441.7 0.0 3.5 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EST41976.1 - 2.1e-103 346.5 14.0 2.1e-103 346.5 14.0 4.6 3 2 1 4 4 3 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 EST41976.1 - 1.3e-76 257.7 0.0 7.4e-76 255.3 0.0 2.5 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 EST41976.1 - 1.4e-67 227.8 0.0 7.6e-67 225.4 0.0 2.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 EST41976.1 - 5.6e-59 198.9 2.4 5.6e-59 198.9 2.4 4.1 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 EST41976.1 - 7.2e-47 159.2 5.4 3.3e-35 121.2 0.0 4.8 5 0 0 5 5 5 3 P-loop containing dynein motor region MT PF12777.7 EST41976.1 - 1.2e-46 159.3 14.6 1.2e-46 159.3 14.6 2.0 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 EST41976.1 - 7.8e-36 122.8 0.6 7.8e-35 119.5 0.1 3.0 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 EST41976.1 - 4.1e-35 121.0 0.6 2.7e-34 118.3 0.6 2.6 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 EST41976.1 - 4.4e-13 49.3 0.1 2.6e-12 46.8 0.1 2.4 1 0 0 1 1 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 EST41976.1 - 2.3e-10 40.7 0.3 6.1e-09 36.1 0.3 3.5 2 1 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 EST41976.1 - 3.1e-07 30.5 0.0 0.2 11.6 0.0 6.1 5 2 0 5 5 4 2 AAA domain (dynein-related subfamily) AAA PF00004.29 EST41976.1 - 3.6e-06 27.4 0.2 0.62 10.5 0.0 4.9 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EST41976.1 - 0.0072 16.6 0.0 13 6.0 0.0 4.6 4 0 0 4 4 4 0 AAA domain RNA_helicase PF00910.22 EST41976.1 - 0.074 13.5 0.3 18 5.8 0.0 4.3 4 0 0 4 4 4 0 RNA helicase HTH_19 PF12844.7 EST41978.1 - 5.9e-07 29.4 0.1 8.5e-07 28.9 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 EST41978.1 - 0.00039 20.4 0.1 0.00059 19.8 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EST41978.1 - 0.044 14.1 0.0 0.066 13.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain AAA_6 PF12774.7 EST41979.1 - 1.6e-92 310.0 2.4 1.6e-92 310.0 2.4 7.3 7 0 0 7 7 7 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EST41979.1 - 9.7e-46 156.6 28.8 9.7e-46 156.6 28.8 9.6 9 1 1 10 10 7 1 Dynein heavy chain, N-terminal region 2 AAA_7 PF12775.7 EST41979.1 - 1.5e-33 115.8 6.0 1.6e-28 99.4 0.4 4.7 3 0 0 3 3 3 3 P-loop containing dynein motor region AAA_8 PF12780.7 EST41979.1 - 6.5e-31 107.6 5.6 6.5e-31 107.6 5.6 5.9 6 0 0 6 6 6 1 P-loop containing dynein motor region D4 MT PF12777.7 EST41979.1 - 6.7e-24 84.6 13.8 1.7e-23 83.2 13.8 1.7 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 EST41979.1 - 1.4e-20 73.7 0.0 3.8e-05 23.7 0.0 5.9 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EST41979.1 - 6.1e-09 36.3 8.4 0.045 14.0 0.0 7.6 7 0 0 7 7 6 2 AAA domain AAA PF00004.29 EST41979.1 - 7.3e-08 32.9 1.8 0.2 12.1 0.0 6.9 6 2 0 6 6 5 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EST41979.1 - 9.4e-08 32.1 0.6 0.00012 22.1 0.0 3.5 3 0 0 3 3 2 2 NACHT domain AAA_lid_11 PF18198.1 EST41979.1 - 4e-05 23.5 0.9 0.00026 20.9 0.0 3.0 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_16 PF13191.6 EST41979.1 - 4.5e-05 23.9 0.0 3.5 8.0 0.0 4.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.6 EST41979.1 - 0.00013 22.1 0.0 0.45 10.7 0.0 3.9 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 EST41979.1 - 0.0017 17.5 0.1 0.1 11.7 0.0 2.9 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_lid_1 PF17857.1 EST41979.1 - 0.003 17.8 0.4 0.055 13.7 0.1 3.6 2 0 0 2 2 1 1 AAA+ lid domain AAA_30 PF13604.6 EST41979.1 - 0.032 13.9 0.0 3 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EST41979.1 - 0.045 14.3 1.0 26 5.4 0.0 5.1 4 0 0 4 4 4 0 AAA domain RNA_helicase PF00910.22 EST41979.1 - 0.064 13.6 6.5 9.5 6.7 0.0 5.1 5 0 0 5 5 3 0 RNA helicase AAA_29 PF13555.6 EST41979.1 - 0.21 11.4 1.0 9.5 6.1 0.0 3.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_19 PF13245.6 EST41979.1 - 0.28 11.5 2.7 11 6.4 0.0 4.4 5 0 0 5 5 4 0 AAA domain LSM PF01423.22 EST41981.1 - 1.6e-12 46.9 0.7 1.8e-12 46.7 0.7 1.1 1 0 0 1 1 1 1 LSM domain GABP-alpha PF11620.8 EST41981.1 - 0.0088 16.2 0.3 0.01 16.0 0.3 1.1 1 0 0 1 1 1 1 GA-binding protein alpha chain Urm1 PF09138.11 EST41984.1 - 2.7e-21 75.7 1.7 3e-21 75.6 1.7 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 EST41984.1 - 0.0044 17.6 0.0 0.0054 17.3 0.0 1.2 1 0 0 1 1 1 1 ThiS family Metallophos PF00149.28 EST41988.1 - 2.8e-08 34.5 2.8 3.5e-08 34.2 0.2 2.2 2 1 1 3 3 3 2 Calcineurin-like phosphoesterase FeoB_N PF02421.18 EST41988.1 - 0.063 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B 5_nucleotid_C PF02872.18 EST41988.1 - 0.077 13.2 0.1 0.27 11.4 0.1 1.9 1 1 0 1 1 1 0 5'-nucleotidase, C-terminal domain QRPTase_C PF01729.19 EST41988.1 - 0.17 11.6 0.0 0.42 10.4 0.0 1.6 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain cEGF PF12662.7 EST41990.1 - 0.0044 16.9 0.6 0.0044 16.9 0.6 4.3 4 0 0 4 4 4 1 Complement Clr-like EGF-like FXa_inhibition PF14670.6 EST41990.1 - 0.0099 16.1 4.8 0.0099 16.1 4.8 3.8 3 1 0 3 3 3 1 Coagulation Factor Xa inhibitory site Lig_chan PF00060.26 EST41992.1 - 0.16 11.8 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Ligand-gated ion channel Caldesmon PF02029.15 EST41994.1 - 0.0015 17.4 22.1 0.0018 17.1 22.1 1.2 1 0 0 1 1 1 1 Caldesmon Peptidase_M49 PF03571.15 EST41995.1 - 2.2e-133 445.6 0.4 3.1e-133 445.1 0.4 1.1 1 0 0 1 1 1 1 Peptidase family M49 NPHI_C PF08469.10 EST41995.1 - 0.062 13.3 0.6 0.97 9.4 0.4 2.6 2 0 0 2 2 2 0 Nucleoside triphosphatase I C-terminal RdRP_4 PF02123.16 EST41995.1 - 0.12 11.2 2.2 0.74 8.6 0.4 2.1 2 0 0 2 2 2 0 Viral RNA-directed RNA-polymerase TatD_DNase PF01026.21 EST41996.1 - 3.9e-42 144.4 0.0 4.4e-42 144.2 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase zf-RING_2 PF13639.6 EST41997.1 - 2.4e-09 37.4 5.9 4e-09 36.7 5.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EST41997.1 - 2.4e-07 30.5 4.5 3.8e-07 29.9 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EST41997.1 - 4.9e-07 29.5 4.4 0.00012 21.8 2.0 2.2 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EST41997.1 - 1.8e-06 27.8 4.9 1.8e-06 27.8 4.9 1.6 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EST41997.1 - 3e-05 23.8 9.7 9.6e-05 22.2 9.6 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EST41997.1 - 0.00016 21.4 6.9 0.00057 19.6 7.0 1.8 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 EST41997.1 - 0.00046 20.0 7.0 0.0011 18.8 7.1 1.6 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EST41997.1 - 0.0012 19.1 6.8 0.0056 16.9 1.7 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EST41997.1 - 0.0028 17.7 5.2 0.0047 16.9 3.8 1.8 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF4428 PF14471.6 EST41997.1 - 0.0098 15.8 1.4 0.24 11.4 0.0 2.6 2 1 1 3 3 3 1 Domain of unknown function (DUF4428) zf-Di19 PF05605.12 EST41997.1 - 0.01 16.1 5.7 0.64 10.3 1.4 2.4 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding Zn_ribbon_17 PF17120.5 EST41997.1 - 0.012 15.2 4.6 0.02 14.5 4.6 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 EST41997.1 - 0.03 14.3 7.2 0.12 12.4 0.9 2.6 3 0 0 3 3 3 0 RING-type zinc-finger zf-C2H2_9 PF16293.5 EST41997.1 - 0.037 13.9 1.9 3.1 7.7 0.0 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) Rad50_zn_hook PF04423.14 EST41997.1 - 0.14 12.0 3.2 3.3 7.6 0.1 2.7 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-RING-like PF08746.11 EST41997.1 - 0.14 12.5 9.5 0.48 10.8 7.9 2.2 1 1 1 2 2 2 0 RING-like domain Cys_rich_CPXG PF14255.6 EST41997.1 - 0.3 11.0 7.5 16 5.5 5.3 2.8 1 1 1 2 2 2 0 Cysteine-rich CPXCG zinc-ribbons_6 PF07191.12 EST41997.1 - 0.31 11.1 5.7 1.2 9.2 4.9 2.0 1 1 1 2 2 2 0 zinc-ribbons FYVE PF01363.21 EST41997.1 - 0.61 10.3 4.6 13 6.0 0.1 2.4 2 1 1 3 3 3 0 FYVE zinc finger zf-C3H2C3 PF17122.5 EST41997.1 - 0.67 10.0 10.3 9.4 6.4 0.1 2.7 2 1 0 2 2 2 0 Zinc-finger zf-C3HC4_5 PF17121.5 EST41997.1 - 0.72 9.8 8.5 2.2 8.2 8.5 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EST41997.1 - 0.9 9.3 5.3 0.81 9.5 1.3 2.4 2 0 0 2 2 2 0 RING-like zinc finger Zn-C2H2_12 PF18112.1 EST41997.1 - 1.5 9.4 4.4 29 5.2 0.4 2.7 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain PHD PF00628.29 EST41997.1 - 2.2 8.2 10.5 1.6 8.7 3.9 2.4 2 1 0 2 2 2 0 PHD-finger Pkinase PF00069.25 EST41998.1 - 2.1e-60 204.3 0.8 2.8e-60 203.9 0.8 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST41998.1 - 1.5e-31 109.6 0.2 2e-31 109.2 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EST41998.1 - 3.5e-06 26.5 0.1 6e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EST41998.1 - 0.006 16.5 0.1 0.033 14.1 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EST41998.1 - 0.017 13.9 0.1 0.024 13.4 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 EST41998.1 - 0.018 14.6 0.4 0.032 13.8 0.4 1.3 1 0 0 1 1 1 0 RIO1 family U3snoRNP10 PF12397.8 EST41998.1 - 0.031 14.6 0.0 0.059 13.7 0.0 1.5 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 10 Pkinase PF00069.25 EST41999.1 - 3.3e-59 200.4 0.7 4.2e-59 200.1 0.7 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST41999.1 - 1.8e-37 129.0 0.2 2.7e-37 128.5 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EST41999.1 - 0.00012 21.5 0.1 0.00029 20.2 0.1 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EST41999.1 - 0.00046 19.1 0.0 0.00069 18.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EST41999.1 - 0.037 13.6 0.8 0.097 12.3 0.4 1.8 1 1 0 2 2 2 0 RIO1 family Kdo PF06293.14 EST41999.1 - 0.07 12.5 0.3 0.13 11.6 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MAAL_C PF07476.11 EST42000.1 - 0.0049 16.1 2.0 1.1 8.4 2.0 2.5 1 1 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus ApoO PF09769.9 EST42000.1 - 0.21 11.5 8.2 0.13 12.2 0.4 3.2 3 0 0 3 3 3 0 Apolipoprotein O TTRAP PF14203.6 EST42000.1 - 0.35 10.9 4.3 0.29 11.1 1.0 2.7 3 0 0 3 3 3 0 Putative tranposon-transfer assisting protein DUF1251 PF06856.11 EST42000.1 - 0.82 9.4 8.9 1 9.1 1.5 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1251) STI1 PF17830.1 EST42001.1 - 2.6e-12 46.5 3.3 2e-11 43.6 2.8 2.4 2 0 0 2 2 2 1 STI1 domain TPR_1 PF00515.28 EST42001.1 - 3.1e-10 39.4 0.1 0.0008 19.1 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EST42001.1 - 4.3e-08 32.7 1.7 0.025 14.7 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat SGTA_dimer PF16546.5 EST42001.1 - 4.4e-07 29.6 0.1 9.5e-07 28.5 0.1 1.5 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_8 PF13181.6 EST42001.1 - 0.00015 21.7 0.5 1.1 9.7 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EST42001.1 - 0.00064 20.0 0.0 0.0015 18.8 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat SNAP PF14938.6 EST42001.1 - 0.013 15.0 0.6 0.024 14.1 0.6 1.4 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP TPR_11 PF13414.6 EST42001.1 - 0.021 14.5 0.1 0.44 10.3 0.0 2.5 2 0 0 2 2 2 0 TPR repeat Exo84_C PF16528.5 EST42001.1 - 0.047 13.5 0.3 0.13 12.0 0.3 1.8 2 0 0 2 2 2 0 Exocyst component 84 C-terminal TPR_19 PF14559.6 EST42001.1 - 0.11 13.1 3.6 0.14 12.7 0.3 2.7 3 1 0 3 3 3 0 Tetratricopeptide repeat HAD_2 PF13419.6 EST42002.1 - 9.7e-30 104.0 0.2 1.2e-29 103.7 0.2 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EST42002.1 - 1.9e-13 51.2 5.0 4.5e-12 46.7 1.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EST42002.1 - 2.5e-08 34.5 0.0 3.6e-08 34.0 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EST42002.1 - 6.9e-06 26.0 0.1 3.3e-05 23.9 0.0 2.0 1 1 1 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EST42002.1 - 0.00018 21.6 0.3 0.0014 18.7 0.3 2.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EST42002.1 - 0.016 14.9 1.4 1 9.1 0.0 3.1 3 1 1 4 4 4 0 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 EST42002.1 - 0.034 14.0 1.1 0.17 11.7 1.1 2.0 1 1 0 1 1 1 0 Acid Phosphatase DUF789 PF05623.12 EST42002.1 - 0.085 12.5 0.1 0.098 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF789) FAD_binding_1 PF00667.20 EST42003.1 - 0.0044 16.6 0.4 0.17 11.4 0.1 2.5 2 0 0 2 2 2 1 FAD binding domain LD_cluster2 PF18163.1 EST42003.1 - 0.029 13.9 0.2 0.44 10.0 0.0 2.2 2 0 0 2 2 2 0 SLOG cluster2 Lipocalin_8 PF16585.5 EST42003.1 - 0.034 14.6 0.6 0.086 13.3 0.6 1.6 1 0 0 1 1 1 0 Lipocalin-like domain PI3_PI4_kinase PF00454.27 EST42004.1 - 8.8e-10 38.8 1.1 1.1e-09 38.5 1.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EST42004.1 - 1.9e-06 27.6 0.4 3.7e-06 26.6 0.4 1.5 1 0 0 1 1 1 1 FATC domain IL34 PF15036.6 EST42004.1 - 0.0026 17.8 1.2 0.011 15.7 0.9 2.1 1 1 0 1 1 1 1 Interleukin 34 TMEM141 PF15110.6 EST42004.1 - 0.015 15.9 0.6 2.9 8.5 0.1 2.4 2 0 0 2 2 2 0 TMEM141 protein family RRM_1 PF00076.22 EST42005.1 - 3.6e-62 206.1 4.6 3.4e-15 55.6 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EST42005.1 - 1.7e-09 37.5 0.0 0.02 14.9 0.0 4.6 4 1 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 EST42005.1 - 7.7e-08 32.0 1.0 0.00074 19.1 0.0 3.6 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EST42005.1 - 1.5e-07 31.4 1.1 0.076 13.1 0.1 4.6 4 0 0 4 4 4 2 Limkain b1 RRM_occluded PF16842.5 EST42005.1 - 0.0014 18.4 1.3 2 8.3 0.0 4.5 4 0 0 4 4 4 1 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 EST42005.1 - 0.0025 17.6 5.5 5.6 6.7 0.0 4.4 4 0 0 4 4 4 2 Rrp7 RRM-like N-terminal domain DbpA PF03880.15 EST42005.1 - 0.017 15.1 0.2 26 4.9 0.0 4.2 4 0 0 4 4 4 0 DbpA RNA binding domain DUF910 PF06014.11 EST42005.1 - 0.076 13.0 0.6 0.38 10.8 0.1 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF910) Annexin PF00191.20 EST42006.1 - 1.9e-22 79.1 11.2 1.3e-11 44.4 0.3 4.1 4 0 0 4 4 4 3 Annexin DUF4284 PF14112.6 EST42006.1 - 0.047 14.6 5.9 1.7 9.6 2.6 2.4 2 0 0 2 2 2 0 Immunity protein 22 MlaC PF05494.12 EST42006.1 - 0.14 11.9 2.7 1.7 8.4 0.0 2.9 3 0 0 3 3 3 0 MlaC protein Annexin PF00191.20 EST42007.1 - 6.5e-52 173.5 10.2 1.1e-18 67.0 0.1 4.9 4 1 0 4 4 4 4 Annexin Annexin PF00191.20 EST42008.1 - 3.1e-54 180.9 5.7 2.1e-16 59.7 0.0 4.4 4 1 0 4 4 4 4 Annexin ZYG-11_interact PF05884.12 EST42008.1 - 0.013 14.9 0.6 0.033 13.6 0.6 1.6 2 0 0 2 2 2 0 Interactor of ZYG-11 SLAIN PF15301.6 EST42009.1 - 0.63 9.2 7.7 1.4 8.1 7.7 1.5 1 0 0 1 1 1 0 SLAIN motif-containing family Tubulin PF00091.25 EST42010.1 - 9.3e-55 185.9 0.1 1.9e-54 184.8 0.1 1.6 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Misat_Tub_SegII PF10644.9 EST42010.1 - 0.00068 19.9 1.5 0.003 17.8 0.0 2.3 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_C PF03953.17 EST42010.1 - 0.00098 19.3 0.0 0.0021 18.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EST42010.1 - 0.085 12.5 0.0 0.76 9.4 0.0 2.1 2 0 0 2 2 2 0 Tubulin domain Bin3 PF06859.12 EST42010.1 - 0.81 10.3 3.3 43 4.8 1.3 2.9 2 1 1 3 3 3 0 Bicoid-interacting protein 3 (Bin3) SL4P PF17618.2 EST42012.1 - 0.013 15.5 3.4 0.14 12.2 0.2 2.8 2 0 0 2 2 2 0 Uncharacterized Strongylid L4 protein DUF4470 PF14737.6 EST42012.1 - 0.057 13.6 0.1 0.13 12.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4470) YWFCY PF14293.6 EST42013.1 - 0.032 14.6 0.1 2.9 8.3 0.0 3.2 2 0 0 2 2 2 0 YWFCY protein Macro PF01661.21 EST42014.1 - 1.5e-05 25.0 0.0 3.2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Macro domain Aminotran_5 PF00266.19 EST42015.1 - 8.9e-28 97.3 0.0 1.5e-27 96.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Rad33 PF08730.10 EST42018.1 - 0.0077 16.3 0.3 0.013 15.5 0.3 1.3 1 0 0 1 1 1 1 Rad33 IU_nuc_hydro PF01156.19 EST42019.1 - 1.5e-35 123.2 0.0 2.7e-35 122.4 0.0 1.3 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DUF2862 PF11061.8 EST42019.1 - 0.01 15.7 0.1 0.035 13.9 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2862) zf-C2H2_2 PF12756.7 EST42020.1 - 1.8e-21 76.3 20.1 1.1e-14 54.6 3.5 3.7 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EST42020.1 - 3.2e-10 40.0 13.2 0.026 15.3 0.1 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EST42020.1 - 1.8e-06 28.0 14.7 2.8e-06 27.5 1.4 4.5 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 EST42020.1 - 9.9e-06 25.7 22.8 0.009 16.4 0.7 4.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-met PF12874.7 EST42020.1 - 2.3e-05 24.6 1.1 2.3e-05 24.6 1.1 4.2 5 0 0 5 5 4 1 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 EST42020.1 - 0.0052 16.6 3.7 0.73 9.8 0.2 2.9 2 0 0 2 2 2 2 zinc-finger of a C2HC-type FAS_N PF17828.1 EST42020.1 - 0.011 15.8 0.4 1.9 8.5 0.0 2.9 3 0 0 3 3 3 0 N-terminal domain in fatty acid synthase subunit beta zf-BED PF02892.15 EST42020.1 - 0.039 14.0 12.1 2.4 8.2 0.2 4.1 4 0 0 4 4 4 0 BED zinc finger Stealth_CR3 PF17102.5 EST42020.1 - 0.058 13.3 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Stealth protein CR3, conserved region 3 zf-C2H2_6 PF13912.6 EST42020.1 - 0.09 12.8 0.6 0.09 12.8 0.6 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2HE PF16278.5 EST42020.1 - 1.9 9.0 24.9 2.1 8.9 1.3 5.3 3 2 2 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger zf-FCS PF06467.14 EST42020.1 - 4.2 7.4 11.1 10 6.2 0.2 3.6 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif HSP70 PF00012.20 EST42021.1 - 4e-203 675.9 5.5 4.5e-203 675.8 5.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EST42021.1 - 3e-17 62.5 0.0 1.5e-15 56.8 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 EST42021.1 - 0.0011 19.4 1.7 1.9 8.9 0.0 3.1 3 2 0 3 3 3 2 Cell division protein FtsA BcrAD_BadFG PF01869.20 EST42021.1 - 0.0085 15.6 0.0 0.89 9.0 0.0 2.4 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family DDR PF08841.10 EST42021.1 - 0.012 14.6 0.1 2.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain GTP_EFTU PF00009.27 EST42023.1 - 6.4e-26 91.1 0.0 9.7e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EST42023.1 - 6.2e-06 26.5 0.9 1.4e-05 25.4 0.9 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 eIF2_C PF09173.11 EST42023.1 - 1.9e-05 24.8 0.0 4.2e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal MMR_HSR1 PF01926.23 EST42023.1 - 3.8e-05 23.8 0.0 7.9e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 EST42023.1 - 0.0053 16.6 0.1 0.1 12.4 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Zn-ribbon_8 PF09723.10 EST42023.1 - 0.0057 16.7 0.6 0.0057 16.7 0.6 2.1 2 0 0 2 2 2 1 Zinc ribbon domain RsgA_GTPase PF03193.16 EST42023.1 - 0.0088 16.0 0.1 0.19 11.6 0.1 2.4 2 1 0 2 2 2 1 RsgA GTPase LRR_6 PF13516.6 EST42024.1 - 1.4e-05 24.7 14.8 2.6 8.3 0.0 8.3 10 0 0 10 10 10 4 Leucine Rich repeat LRR_8 PF13855.6 EST42024.1 - 0.11 12.3 6.4 3.5 7.5 1.6 3.8 4 1 1 5 5 5 0 Leucine rich repeat Peptidase_M90 PF06167.12 EST42025.1 - 0.0052 16.4 0.0 0.0078 15.8 0.0 1.2 1 0 0 1 1 1 1 Glucose-regulated metallo-peptidase M90 NTNH_C PF08470.10 EST42028.1 - 0.049 13.5 0.2 0.12 12.3 0.1 1.6 1 1 0 2 2 2 0 Nontoxic nonhaemagglutinin C-terminal UL2 PF08196.11 EST42030.1 - 0.1 12.6 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 UL2 protein RICTOR_M PF14666.6 EST42031.1 - 0.025 14.3 2.6 0.91 9.3 0.3 3.0 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain DUF2341 PF10102.9 EST42031.1 - 0.49 11.0 6.6 1.4 9.5 0.6 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF2341) DUF3552 PF12072.8 EST42032.1 - 0.0043 16.5 0.9 0.0052 16.2 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) adh_short PF00106.25 EST42033.1 - 7.8e-32 110.3 0.0 1e-31 109.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EST42033.1 - 4.4e-19 69.0 0.0 5.8e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EST42033.1 - 2.4e-05 24.0 0.0 4e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EST42033.1 - 3.7e-05 23.7 0.0 5.7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EST42033.1 - 0.0056 16.6 0.0 0.0096 15.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EST42033.1 - 0.091 11.8 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Pkinase PF00069.25 EST42034.1 - 3.4e-50 170.9 3.1 5.4e-50 170.2 3.1 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST42034.1 - 2.9e-26 92.3 0.5 4.5e-26 91.7 0.5 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 EST42034.1 - 4.1e-05 23.3 1.6 0.021 14.5 0.2 2.5 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 DUF3086 PF11285.8 EST42034.1 - 0.011 14.9 0.3 0.022 13.9 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) APH PF01636.23 EST42034.1 - 0.012 15.5 0.0 4.1 7.2 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 EST42034.1 - 0.013 15.2 0.3 0.037 13.6 0.3 1.8 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 EST42034.1 - 0.023 13.5 0.3 0.023 13.5 0.3 1.6 2 0 0 2 2 2 0 Fungal protein kinase Cor1 PF04803.12 EST42034.1 - 0.045 14.0 0.4 0.045 14.0 0.4 2.5 3 0 0 3 3 3 0 Cor1/Xlr/Xmr conserved region DUF3352 PF11832.8 EST42034.1 - 0.095 11.3 3.7 3.4 6.2 0.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3352) POLO_box PF00659.18 EST42035.1 - 0.051 13.8 0.3 0.39 11.0 0.0 2.5 2 0 0 2 2 2 0 POLO box duplicated region DUF2911 PF11138.8 EST42035.1 - 0.22 11.4 1.0 0.42 10.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2911) AKAP2_C PF15304.6 EST42036.1 - 0.018 14.3 0.6 0.022 14.1 0.6 1.1 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus TNFR_16_TM PF18422.1 EST42036.1 - 0.57 10.2 3.0 0.97 9.4 3.0 1.3 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain PPTA PF01239.22 EST42037.1 - 0.16 11.7 5.7 0.95 9.3 0.1 3.6 4 0 0 4 4 4 0 Protein prenyltransferase alpha subunit repeat Prenyltrans PF00432.21 EST42038.1 - 0.049 13.4 0.1 2.2 8.1 0.0 2.8 3 0 0 3 3 3 0 Prenyltransferase and squalene oxidase repeat SprT-like PF10263.9 EST42039.1 - 5.6e-16 58.4 0.1 8.3e-16 57.8 0.1 1.2 1 0 0 1 1 1 1 SprT-like family Peptidase_M50B PF13398.6 EST42039.1 - 0.062 12.9 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 Peptidase M50B-like POR_N PF01855.19 EST42040.1 - 7.9e-54 182.8 0.2 1.3e-53 182.1 0.2 1.3 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 EST42040.1 - 1.3e-17 64.4 0.5 2.4e-17 63.6 0.5 1.4 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase TPP_enzyme_C PF02775.21 EST42040.1 - 1.2e-09 38.1 0.3 5.7e-09 35.9 0.2 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4_7 PF12838.7 EST42040.1 - 5e-08 33.4 13.2 1.5e-07 31.9 13.2 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain PFOR_II PF17147.4 EST42040.1 - 1.7e-07 31.5 0.0 4.4e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Fer4 PF00037.27 EST42040.1 - 6.8e-07 28.8 20.4 0.00031 20.4 4.5 2.9 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_21 PF14697.6 EST42040.1 - 9.2e-07 28.9 10.3 3.4e-06 27.1 10.2 2.1 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 EST42040.1 - 7.5e-06 25.7 17.1 0.0028 17.7 3.1 3.9 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_10 PF13237.6 EST42040.1 - 1.1e-05 25.4 12.3 2.6e-05 24.3 11.5 2.1 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 EST42040.1 - 0.00011 22.1 22.1 0.00086 19.3 5.7 3.6 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_16 PF13484.6 EST42040.1 - 0.00014 22.7 16.5 0.0014 19.5 14.7 2.9 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 EST42040.1 - 0.002 18.2 19.2 0.011 15.9 16.8 2.6 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_17 PF13534.6 EST42040.1 - 0.0022 18.5 13.3 0.048 14.2 0.9 3.3 3 0 0 3 3 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 EST42040.1 - 0.0089 16.5 16.5 0.22 12.1 4.5 3.0 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 EST42040.1 - 0.024 15.1 14.2 0.29 11.6 15.3 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 EST42040.1 - 0.11 12.7 6.6 1.6 8.9 0.3 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 EST42040.1 - 0.37 11.4 17.2 0.31 11.6 2.0 2.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I DUF4481 PF14800.6 EST42042.1 - 0.37 10.2 2.3 0.57 9.6 2.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) RAP80_UIM PF18282.1 EST42042.1 - 2.6 7.9 6.5 2.8 7.8 3.0 2.4 2 0 0 2 2 2 0 RAP80 N-terminal ubiquitin interaction motif YabA PF06156.13 EST42043.1 - 0.0095 16.6 13.6 0.032 14.9 7.0 2.3 1 1 1 2 2 2 1 Initiation control protein YabA KASH_CCD PF14662.6 EST42043.1 - 0.019 14.8 19.6 0.02 14.7 11.1 2.0 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH ZapB PF06005.12 EST42043.1 - 0.023 15.2 7.3 0.023 15.2 7.3 2.3 1 1 0 2 2 2 0 Cell division protein ZapB DUF1471 PF07338.13 EST42043.1 - 0.024 14.6 5.2 0.93 9.5 0.1 3.1 3 1 1 4 4 3 0 Protein of unknown function (DUF1471) AIG1 PF04548.16 EST42043.1 - 0.031 13.6 7.8 0.046 13.0 7.7 1.3 1 1 0 1 1 1 0 AIG1 family DASH_Dam1 PF08653.10 EST42043.1 - 0.047 13.5 7.7 0.31 10.9 0.3 3.1 3 0 0 3 3 3 0 DASH complex subunit Dam1 DUF1204 PF06721.11 EST42043.1 - 0.078 12.4 8.5 0.086 12.3 8.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) Herpes_BLRF2 PF05812.12 EST42043.1 - 0.1 12.8 6.0 0.18 11.9 5.9 1.6 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein DUF4734 PF15881.5 EST42043.1 - 0.11 12.6 3.1 0.59 10.3 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4734) AAA_23 PF13476.6 EST42043.1 - 0.14 12.6 22.7 0.2 12.1 22.7 1.2 1 0 0 1 1 1 0 AAA domain RNA_pol_Rpb4 PF03874.16 EST42043.1 - 0.18 12.1 9.1 0.24 11.8 9.1 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb4 V_ATPase_I PF01496.19 EST42043.1 - 0.28 9.0 12.1 0.3 8.9 12.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Flagellin_N PF00669.20 EST42043.1 - 0.36 10.9 9.2 0.065 13.3 4.9 1.8 1 1 0 2 2 2 0 Bacterial flagellin N-terminal helical region Cep57_CLD_2 PF14197.6 EST42043.1 - 0.42 10.7 12.5 0.74 10.0 5.2 2.8 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 GCN5L1 PF06320.13 EST42043.1 - 0.52 10.5 14.8 0.35 11.0 5.9 2.2 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) Jnk-SapK_ap_N PF09744.9 EST42043.1 - 0.58 10.4 15.9 1.5 9.0 16.0 1.7 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 TSC22 PF01166.18 EST42043.1 - 0.58 10.5 8.4 0.78 10.1 0.1 2.8 2 1 1 3 3 3 0 TSC-22/dip/bun family TMF_TATA_bd PF12325.8 EST42043.1 - 0.62 10.3 16.1 3.8 7.8 7.8 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding HemX PF04375.14 EST42043.1 - 0.82 8.9 16.1 0.13 11.5 10.5 1.8 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF1664 PF07889.12 EST42043.1 - 1.2 9.2 13.0 0.76 9.8 6.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) THOC7 PF05615.13 EST42043.1 - 1.3 9.4 16.3 3.5 7.9 14.2 2.0 1 1 1 2 2 2 0 Tho complex subunit 7 PCRF PF03462.18 EST42043.1 - 1.3 8.8 11.2 2.2 8.1 11.2 1.4 1 1 0 1 1 1 0 PCRF domain Prefoldin_2 PF01920.20 EST42043.1 - 1.5 8.8 24.2 0.62 10.1 7.6 2.8 1 1 2 3 3 3 0 Prefoldin subunit UPF0449 PF15136.6 EST42043.1 - 1.7 9.1 15.1 0.14 12.6 6.9 2.5 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 TPR_MLP1_2 PF07926.12 EST42043.1 - 2 8.5 19.4 7.2 6.7 19.4 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Seryl_tRNA_N PF02403.22 EST42043.1 - 2.2 8.6 19.7 4.3 7.6 10.0 2.1 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain SlyX PF04102.12 EST42043.1 - 2.2 9.0 16.6 1.6 9.4 2.4 3.0 2 1 1 3 3 3 0 SlyX Atg14 PF10186.9 EST42043.1 - 2.9 6.9 14.8 4 6.4 14.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Laminin_II PF06009.12 EST42043.1 - 3.4 7.7 14.1 0.31 11.1 6.9 2.0 1 1 0 1 1 1 0 Laminin Domain II LPD5 PF18799.1 EST42043.1 - 4.1 7.8 12.5 3 8.2 10.5 1.7 1 1 1 2 2 2 0 Large polyvalent protein-associated domain 5 APG6_N PF17675.1 EST42043.1 - 4.2 7.9 21.6 11 6.6 4.6 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF948 PF06103.11 EST42043.1 - 4.6 7.6 8.2 4.4 7.6 2.0 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Syntaxin-6_N PF09177.11 EST42043.1 - 4.7 7.8 10.8 8.3 7.0 8.7 2.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Fib_alpha PF08702.10 EST42043.1 - 5.8 7.1 15.3 30 4.8 15.3 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DivIC PF04977.15 EST42043.1 - 7 6.5 26.7 1.8 8.4 2.6 3.1 1 1 2 3 3 3 0 Septum formation initiator DUF3450 PF11932.8 EST42043.1 - 7.2 5.8 19.1 2.1e+02 1.1 19.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF2203 PF09969.9 EST42043.1 - 7.5 7.3 11.3 0.91 10.3 4.4 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) SPAM PF02090.15 EST42043.1 - 7.6 6.3 17.6 0.62 9.9 6.4 2.4 1 1 1 2 2 2 0 Salmonella surface presentation of antigen gene type M protein DUF4446 PF14584.6 EST42043.1 - 8.4 6.4 15.6 3.5 7.6 5.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) WXG100 PF06013.12 EST42043.1 - 9.5 6.5 13.6 10 6.4 1.5 3.1 1 1 2 3 3 3 0 Proteins of 100 residues with WXG Ax_dynein_light PF10211.9 EST42043.1 - 9.8 6.1 22.0 2.5 8.0 4.2 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain DUF745 PF05335.13 EST42046.1 - 0.33 10.7 4.9 0.68 9.6 4.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF3929 PF13066.6 EST42047.1 - 0.15 12.1 0.1 0.82 9.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3929) F-112 PF09645.10 EST42048.1 - 0.03 14.4 0.7 0.03 14.4 0.7 1.9 3 0 0 3 3 3 0 F-112 protein Cas_DxTHG PF09455.10 EST42050.1 - 0.011 15.4 8.7 0.013 15.1 8.7 1.0 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family UPF0242 PF06785.11 EST42050.1 - 5.7 7.0 24.7 34 4.5 24.7 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Pkinase PF00069.25 EST42054.1 - 6.1e-40 137.2 0.7 7.9e-39 133.6 0.7 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST42054.1 - 6.5e-17 61.7 0.3 1.6e-16 60.4 0.1 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Choline_kinase PF01633.20 EST42054.1 - 0.002 17.8 0.2 0.0045 16.6 0.2 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 EST42054.1 - 0.0057 16.3 0.1 0.011 15.3 0.1 1.5 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 EST42054.1 - 0.013 15.2 0.4 2.4 7.7 0.1 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EST42054.1 - 0.042 13.8 0.0 0.56 10.1 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family PK PF00224.21 EST42055.1 - 1.4e-05 24.2 0.0 2.1e-05 23.6 0.0 1.3 1 1 0 1 1 1 1 Pyruvate kinase, barrel domain DUF1358 PF07096.11 EST42055.1 - 0.12 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1358) T4SS_TraI PF16932.5 EST42057.1 - 0.02 14.1 0.2 0.18 10.9 0.2 2.3 2 0 0 2 2 2 0 Type IV secretory system, conjugal DNA-protein transfer V-SNARE_C PF12352.8 EST42058.1 - 8e-05 22.8 1.6 8e-05 22.8 1.6 2.7 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus zf-C4H2 PF10146.9 EST42058.1 - 0.0046 17.3 2.6 0.0065 16.8 2.6 1.2 1 0 0 1 1 1 1 Zinc finger-containing protein Glutaredoxin2_C PF04399.13 EST42058.1 - 0.022 14.6 4.5 0.046 13.6 0.8 2.6 1 1 1 2 2 2 0 Glutaredoxin 2, C terminal domain YebG PF07130.12 EST42058.1 - 0.035 14.0 0.1 0.4 10.6 0.0 2.4 2 0 0 2 2 2 0 YebG protein Syntaxin-6_N PF09177.11 EST42058.1 - 0.044 14.3 3.7 0.19 12.3 3.7 2.2 1 1 0 1 1 1 0 Syntaxin 6, N-terminal MbeB_N PF04837.12 EST42058.1 - 0.063 13.6 0.4 25 5.3 0.0 2.7 2 0 0 2 2 2 0 MbeB-like, N-term conserved region Phycobilisome PF00502.19 EST42058.1 - 0.074 13.0 3.3 2 8.3 0.3 2.3 2 0 0 2 2 2 0 Phycobilisome protein Kinesin_assoc PF16183.5 EST42058.1 - 0.1 12.7 3.5 0.073 13.2 2.0 1.5 1 1 1 2 2 2 0 Kinesin-associated Occludin_ELL PF07303.13 EST42058.1 - 0.16 12.7 3.9 0.14 12.9 1.0 2.1 1 1 0 2 2 2 0 Occludin homology domain Focal_AT PF03623.13 EST42058.1 - 0.46 10.5 8.2 0.7 9.9 3.3 2.3 1 1 1 2 2 2 0 Focal adhesion targeting region T3SS_ATPase_C PF18269.1 EST42058.1 - 0.49 10.3 8.8 1.2 9.0 0.8 3.5 3 1 1 4 4 4 0 T3SS EscN ATPase C-terminal domain DUF745 PF05335.13 EST42058.1 - 0.62 9.8 13.3 0.66 9.7 4.3 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF745) CHASE3 PF05227.13 EST42058.1 - 0.69 9.8 7.3 0.46 10.4 2.6 2.2 1 1 0 2 2 2 0 CHASE3 domain DUF2524 PF10732.9 EST42058.1 - 0.81 10.0 10.4 0.069 13.5 3.2 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2524) Laminin_II PF06009.12 EST42058.1 - 1.3 9.0 12.4 0.44 10.6 1.5 2.6 1 1 0 2 2 2 0 Laminin Domain II TMPIT PF07851.13 EST42058.1 - 1.8 7.7 8.4 1.2 8.3 3.3 2.0 1 1 1 2 2 2 0 TMPIT-like protein DUF948 PF06103.11 EST42058.1 - 7 7.0 14.9 1e+03 0.0 14.9 3.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Peptidase_C1 PF00112.23 EST42060.1 - 1.8e-54 185.2 11.4 2e-54 185.0 11.4 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EST42060.1 - 1.8e-08 33.6 0.8 0.00014 20.8 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family EF1G PF00647.19 EST42061.1 - 0.091 12.8 1.4 0.3 11.2 0.5 2.0 1 1 1 2 2 2 0 Elongation factor 1 gamma, conserved domain MCM PF00493.23 EST42062.1 - 6.2e-86 287.1 0.3 1e-85 286.4 0.3 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EST42062.1 - 4.3e-22 78.3 0.3 8.3e-22 77.4 0.3 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EST42062.1 - 1.7e-20 73.2 0.2 3.5e-20 72.2 0.2 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 EST42062.1 - 1.1e-09 38.0 0.1 1.6e-06 27.6 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EST42062.1 - 9e-07 29.0 0.1 7.5e-06 26.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EST42062.1 - 5.8e-05 23.0 0.0 0.00015 21.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EST42062.1 - 0.047 13.4 0.0 0.62 9.8 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain DNA_pol3_tau_4 PF12168.8 EST42064.1 - 0.045 14.3 24.5 4.7 7.8 1.4 7.6 1 1 5 6 6 6 0 DNA polymerase III subunits tau domain IV DnaB-binding HisKA_4TM PF16926.5 EST42064.1 - 0.065 12.8 0.8 2.6 7.6 0.1 3.3 1 1 4 6 6 6 0 Archaeal 4TM region of histidine kinase DUF5398 PF17376.2 EST42064.1 - 0.2 12.3 9.6 6.5 7.5 0.3 4.6 1 1 5 7 7 7 0 Family of unknown function (DUF5398) DUF948 PF06103.11 EST42064.1 - 0.24 11.7 18.4 12 6.3 2.6 5.0 1 1 5 6 6 6 0 Bacterial protein of unknown function (DUF948) ENTH PF01417.20 EST42064.1 - 0.67 10.0 8.2 0.5 10.4 0.3 3.4 1 1 1 2 2 2 0 ENTH domain Zincin_2 PF10103.9 EST42064.1 - 0.76 9.0 8.8 1.6e+02 1.3 8.8 2.7 1 1 0 1 1 1 0 Zincin-like metallopeptidase MRP-S27 PF10037.9 EST42064.1 - 2.9 6.6 23.0 20 3.9 3.7 3.3 1 1 1 2 2 2 0 Mitochondrial 28S ribosomal protein S27 Peptidase_C1 PF00112.23 EST42066.1 - 2.8e-58 197.6 9.6 3.3e-58 197.4 9.6 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EST42066.1 - 7.1e-10 38.2 0.4 0.00028 19.8 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family zf-RING_2 PF13639.6 EST42067.1 - 2.5e-11 43.7 24.8 6.5e-07 29.6 9.0 2.6 2 1 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.6 EST42067.1 - 2.1e-08 34.0 24.0 6.4e-06 26.0 9.5 2.3 2 0 0 2 2 2 2 zinc-RING finger domain zf-RING_11 PF17123.5 EST42067.1 - 2.2e-08 33.7 12.1 4.5e-06 26.3 3.9 3.5 2 1 0 2 2 2 2 RING-like zinc finger zf-rbx1 PF12678.7 EST42067.1 - 1.4e-07 31.7 19.4 0.0011 19.2 5.6 2.5 2 0 0 2 2 2 2 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EST42067.1 - 7.8e-05 22.5 8.1 7.8e-05 22.5 8.1 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EST42067.1 - 0.00011 22.0 8.8 0.00011 22.0 8.8 3.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EST42067.1 - 0.00042 20.1 7.4 0.00042 20.1 7.4 3.1 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EST42067.1 - 0.0015 18.5 8.6 0.029 14.4 1.7 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EST42067.1 - 0.0016 18.5 4.0 0.0016 18.5 4.0 3.0 2 1 1 3 3 3 1 RING-type zinc-finger Rtf2 PF04641.12 EST42067.1 - 0.19 11.1 8.8 0.16 11.3 1.1 2.4 2 0 0 2 2 2 0 Rtf2 RING-finger zf-C3H2C3 PF17122.5 EST42067.1 - 0.63 10.1 21.5 0.063 13.3 7.9 2.5 2 0 0 2 2 2 0 Zinc-finger zf-RING_9 PF13901.6 EST42067.1 - 1.8 8.5 24.9 3.5 7.5 9.5 2.7 2 2 0 2 2 2 0 Putative zinc-RING and/or ribbon zf-Di19 PF05605.12 EST42067.1 - 3 8.2 14.9 9.7 6.6 0.1 3.7 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding TerY_C PF15616.6 EST42067.1 - 3.4 7.8 19.3 0.046 13.8 3.4 2.8 3 1 0 3 3 3 0 TerY-C metal binding domain DUF5415 PF17436.2 EST42068.1 - 0.043 13.9 0.1 0.096 12.8 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5415) ThiS PF02597.20 EST42068.1 - 0.058 14.0 0.4 0.23 12.1 0.1 2.0 2 0 0 2 2 2 0 ThiS family SF-assemblin PF06705.11 EST42070.1 - 2.6e-06 26.9 21.1 0.00069 19.0 14.9 2.6 1 1 1 2 2 2 2 SF-assemblin/beta giardin Baculo_PEP_C PF04513.12 EST42070.1 - 0.01 15.9 13.6 0.12 12.4 1.0 3.5 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 EST42070.1 - 0.045 14.2 9.1 5.9 7.4 0.7 3.9 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein SRA1 PF07304.11 EST42070.1 - 0.065 13.0 0.4 0.065 13.0 0.4 2.2 2 1 0 2 2 2 0 Steroid receptor RNA activator (SRA1) Cytochrom_C_2 PF01322.20 EST42070.1 - 0.17 12.8 6.5 1.2 10.0 0.2 2.8 1 1 1 2 2 2 0 Cytochrome C' MtrG PF04210.13 EST42070.1 - 0.25 11.2 1.0 28 4.7 0.1 3.0 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G TetR_C_13 PF16925.5 EST42070.1 - 0.56 10.2 8.3 0.15 12.0 0.7 2.8 2 2 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Muted PF14942.6 EST42070.1 - 0.67 10.3 25.0 0.79 10.1 7.8 2.2 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein UPF0184 PF03670.13 EST42070.1 - 3.7 8.0 9.8 22 5.5 0.1 3.9 2 2 2 4 4 4 0 Uncharacterised protein family (UPF0184) DUF2115 PF09888.9 EST42070.1 - 3.9 8.0 9.4 0.55 10.7 1.6 2.7 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2115) DUF4718 PF15842.5 EST42070.1 - 5 6.9 7.0 0.41 10.4 0.8 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4718) HalX PF08663.10 EST42070.1 - 5 7.5 15.8 0.38 11.1 1.4 4.0 2 1 2 4 4 4 0 HalX domain FAST_2 PF08368.12 EST42070.1 - 5.2 7.9 6.3 8 7.3 0.6 2.8 2 1 1 3 3 3 0 FAST kinase-like protein, subdomain 2 DUF948 PF06103.11 EST42070.1 - 5.2 7.4 8.3 3.3 8.0 0.4 2.9 3 1 1 4 4 3 0 Bacterial protein of unknown function (DUF948) Atg14 PF10186.9 EST42070.1 - 7.8 5.5 21.2 2.3 7.2 10.8 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3947 PF13135.6 EST42071.1 - 0.0016 18.6 7.2 0.69 10.1 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3947) TetR_C_10 PF16295.5 EST42071.1 - 0.017 15.4 0.6 0.033 14.5 0.2 1.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain CbiK PF06180.11 EST42071.1 - 0.017 14.4 5.6 0.072 12.4 5.6 1.9 1 1 0 1 1 1 0 Cobalt chelatase (CbiK) RPA PF10134.9 EST42071.1 - 0.028 13.9 0.1 0.036 13.5 0.1 1.3 1 0 0 1 1 1 0 Replication initiator protein A WD40_3 PF15911.5 EST42071.1 - 0.074 13.1 0.1 0.28 11.2 0.0 1.9 2 0 0 2 2 2 0 WD domain, G-beta repeat Robl_LC7 PF03259.17 EST42073.1 - 2.3e-17 62.5 0.0 2.8e-17 62.3 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 EST42073.1 - 0.006 16.5 0.0 0.0083 16.0 0.0 1.2 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 PSD4 PF07631.11 EST42074.1 - 0.06 13.9 0.3 0.17 12.4 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1592) F_actin_bund_C PF18060.1 EST42074.1 - 0.077 13.1 0.4 0.25 11.5 0.4 1.9 1 0 0 1 1 1 0 F actin bundling C terminal Blt1 PF12754.7 EST42074.1 - 0.69 10.2 4.4 0.83 10.0 0.3 2.2 2 0 0 2 2 2 0 Blt1 N-terminal domain DUF573 PF04504.14 EST42074.1 - 3.2 8.5 9.1 5.3 7.8 1.2 3.0 2 2 0 2 2 2 0 Protein of unknown function, DUF573 GTP_EFTU PF00009.27 EST42075.1 - 2.6e-42 144.6 0.0 6.2e-42 143.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EST42075.1 - 8.3e-05 22.5 0.1 0.00028 20.8 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus zf-TRAF PF02176.18 EST42076.1 - 6.9e-17 61.9 17.7 1e-09 38.9 6.8 3.4 2 1 1 3 3 3 2 TRAF-type zinc finger ANAPC4_WD40 PF12894.7 EST42077.1 - 1.2e-13 51.1 0.0 0.041 14.2 0.0 7.6 6 2 2 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EST42077.1 - 1e-08 35.7 0.4 4.2 8.4 0.0 7.9 8 0 0 8 8 8 2 WD domain, G-beta repeat BBS2_Mid PF14783.6 EST42077.1 - 3.9e-05 23.6 0.3 0.0092 16.0 0.0 3.9 3 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Mcl1_mid PF12341.8 EST42077.1 - 0.001 18.5 4.1 0.075 12.4 0.0 4.3 4 1 1 5 5 5 1 Minichromosome loss protein, Mcl1, middle region Kelch_6 PF13964.6 EST42077.1 - 0.15 12.4 0.2 3.5 8.0 0.0 3.0 2 0 0 2 2 2 0 Kelch motif Noelin-1 PF12308.8 EST42077.1 - 0.64 10.0 4.0 8.4 6.4 0.5 2.7 2 0 0 2 2 2 0 Neurogenesis glycoprotein MafB19-deam PF14437.6 EST42078.1 - 1.9e-16 60.0 2.6 2.2e-16 59.9 2.6 1.0 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 EST42078.1 - 6.5e-14 51.6 5.3 8.8e-14 51.2 5.3 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region NAD1 PF18778.1 EST42078.1 - 2.7e-05 24.3 0.4 4.5e-05 23.6 0.4 1.3 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 SNAD4 PF18750.1 EST42078.1 - 3.1e-05 24.1 0.3 6.2e-05 23.1 0.3 1.5 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 EST42078.1 - 4.5e-05 23.6 0.2 7.1e-05 22.9 0.2 1.3 1 0 0 1 1 1 1 APOBEC2 NAD2 PF18782.1 EST42078.1 - 0.0007 19.7 0.7 0.00088 19.4 0.7 1.3 1 1 0 1 1 1 1 Novel AID APOBEC clade 2 APOBEC3 PF18771.1 EST42078.1 - 0.0012 19.0 1.8 0.0042 17.2 0.9 1.9 1 1 1 2 2 2 1 APOBEC3 Inv-AAD PF18785.1 EST42078.1 - 0.0014 18.4 0.2 0.0022 17.9 0.2 1.4 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase APOBEC_N PF08210.11 EST42078.1 - 0.0034 17.3 1.6 0.0042 17.0 1.6 1.3 1 1 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC4_like PF18774.1 EST42078.1 - 0.012 15.5 1.0 0.028 14.4 0.4 1.7 1 1 0 2 2 2 0 APOBEC4-like -AID/APOBEC-deaminase Bd3614-deam PF14439.6 EST42078.1 - 0.34 11.0 5.4 1.2 9.2 1.5 2.3 1 1 1 2 2 2 0 Bd3614-like deaminase zf-UBR PF02207.20 EST42079.1 - 1.6e-09 37.7 18.2 1.6e-09 37.7 18.2 3.4 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) PS_Dcarbxylase PF02666.15 EST42080.1 - 4.5e-09 36.1 0.2 7.8e-09 35.4 0.2 1.4 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Adhesin_E PF16747.5 EST42082.1 - 0.028 14.4 1.2 0.057 13.5 1.2 1.5 1 1 0 1 1 1 0 Surface-adhesin protein E BCNT PF07572.12 EST42083.1 - 5.6e-05 23.1 0.8 5.6e-05 23.1 0.8 2.1 2 1 0 2 2 2 1 Bucentaur or craniofacial development FlaG PF03646.15 EST42083.1 - 0.045 13.9 8.3 0.1 12.8 8.3 1.6 1 0 0 1 1 1 0 FlaG protein GvpK PF05121.12 EST42083.1 - 0.055 13.5 0.6 0.68 10.0 0.6 2.1 2 0 0 2 2 2 0 Gas vesicle protein K putAbiC PF16872.5 EST42083.1 - 0.29 11.9 0.1 0.29 11.9 0.1 2.4 2 1 0 2 2 2 0 Putative phage abortive infection protein TORC_M PF12885.7 EST42083.1 - 1.5 8.7 5.8 1.4 8.8 4.8 1.5 1 1 0 1 1 1 0 Transducer of regulated CREB activity middle domain zf-P11 PF03854.14 EST42086.1 - 0.025 14.2 9.5 0.06 13.0 9.5 1.6 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_5 PF14634.6 EST42086.1 - 0.078 13.0 14.8 0.2 11.7 14.8 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 EST42086.1 - 2.1 8.3 13.6 5.9 6.9 13.6 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EST42086.1 - 2.9 7.8 12.7 5.6 6.9 12.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ILEI PF15711.5 EST42086.1 - 3 8.4 6.5 1.7 9.2 0.6 2.9 3 0 0 3 3 3 0 Interleukin-like EMT inducer RED_C PF07807.11 EST42087.1 - 0.071 13.6 1.8 0.11 13.0 0.0 2.1 2 0 0 2 2 2 0 RED-like protein C-terminal region FOP_dimer PF09398.10 EST42089.1 - 0.00013 22.1 0.0 0.00019 21.6 0.0 1.2 1 0 0 1 1 1 1 FOP N terminal dimerisation domain Porphobil_deam PF01379.20 EST42089.1 - 0.075 12.5 0.0 0.086 12.3 0.0 1.1 1 0 0 1 1 1 0 Porphobilinogen deaminase, dipyromethane cofactor binding domain DUF2890 PF11081.8 EST42090.1 - 6.9 6.8 8.1 5.4 7.1 2.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) LRR_4 PF12799.7 EST42091.1 - 4.5e-07 30.1 14.0 0.00071 19.9 1.1 3.2 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EST42091.1 - 1.5e-06 27.9 11.1 1.4e-05 24.8 7.2 2.9 3 1 1 4 4 4 2 Leucine rich repeat LRR_9 PF14580.6 EST42091.1 - 6.5e-05 22.5 1.2 0.00011 21.8 1.2 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 EST42091.1 - 0.67 10.7 13.3 1.8 9.4 0.5 4.3 3 1 0 3 3 3 0 Leucine Rich Repeat Furin-like PF00757.20 EST42092.1 - 2.2e-08 34.1 114.8 0.016 15.1 22.8 7.8 1 1 5 6 6 6 6 Furin-like cysteine rich region VPS13 PF16908.5 EST42093.1 - 3e-21 76.3 11.3 3e-21 76.3 11.3 9.5 9 3 2 11 11 11 3 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 EST42093.1 - 1.3e-19 70.4 3.4 1.3e-19 70.4 3.4 8.0 7 2 1 8 8 8 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 EST42093.1 - 0.00015 22.0 0.0 0.00058 20.2 0.0 2.0 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain ATP-gua_PtransN PF02807.15 EST42093.1 - 0.026 14.9 0.0 0.099 13.1 0.0 2.0 1 0 0 1 1 1 0 ATP:guanido phosphotransferase, N-terminal domain DUF2407 PF10302.9 EST42094.1 - 0.0011 19.5 1.5 0.0023 18.5 0.0 2.1 2 1 0 2 2 2 1 DUF2407 ubiquitin-like domain RXLR_WY PF18634.1 EST42094.1 - 0.12 12.3 0.9 0.27 11.2 0.9 1.6 1 0 0 1 1 1 0 RXLR phytopathogen effector protein WY-domain ESAG1 PF03238.13 EST42094.1 - 0.15 11.5 1.3 0.18 11.2 1.3 1.2 1 0 0 1 1 1 0 ESAG protein Herpes_UL43 PF05072.13 EST42094.1 - 0.27 10.3 0.0 0.34 10.0 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL43 protein Bac_small_YrzI PF09501.10 EST42094.1 - 0.39 10.9 3.9 13 6.0 0.1 3.1 3 0 0 3 3 3 0 Probable sporulation protein (Bac_small_yrzI) HMG_box PF00505.19 EST42095.1 - 9.1e-08 32.4 14.9 1.3e-06 28.7 9.1 2.8 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 EST42095.1 - 1.7e-05 25.3 15.3 0.00011 22.7 9.3 2.4 2 0 0 2 2 2 2 HMG-box domain HMG_box_5 PF14887.6 EST42095.1 - 0.00046 20.1 6.2 0.00046 20.1 6.2 2.0 2 1 0 2 2 2 1 HMG (high mobility group) box 5 NUC PF18510.1 EST42095.1 - 0.71 10.3 5.6 0.34 11.3 2.7 1.8 1 1 1 2 2 2 0 Nuclease domain NPHI_C PF08469.10 EST42098.1 - 0.003 17.6 0.1 0.0096 15.9 0.0 1.9 2 0 0 2 2 2 1 Nucleoside triphosphatase I C-terminal Microtub_bind PF13931.6 EST42098.1 - 0.068 13.6 0.2 0.13 12.6 0.2 1.5 1 0 0 1 1 1 0 Kinesin-associated microtubule-binding DUF5600 PF18150.1 EST42099.1 - 0.38 11.4 10.6 0.066 13.8 4.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF5600) MatE PF01554.18 EST42101.1 - 1.6e-05 24.6 25.5 0.00077 19.1 17.4 2.7 2 0 0 2 2 2 2 MatE PAPS_reduct PF01507.19 EST42103.1 - 0.0043 17.1 0.2 0.0043 17.1 0.2 2.1 2 1 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family ASFV_L11L PF05293.11 EST42105.1 - 0.011 16.1 1.0 0.029 14.7 0.1 2.1 2 0 0 2 2 2 0 African swine fever virus (ASFV) L11L protein DUF2577 PF10844.8 EST42106.1 - 0.6 10.4 3.1 0.67 10.2 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2577) Raptor_N PF14538.6 EST42109.1 - 0.015 15.3 0.3 0.039 13.9 0.1 1.8 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain TFIIA PF03153.13 EST42112.1 - 0.028 14.4 22.0 0.035 14.1 22.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NPF PF16601.5 EST42112.1 - 9.5 6.6 12.9 0.086 13.3 1.6 2.2 1 1 1 2 2 2 0 Rabosyn-5 repeating NPF sequence-motif TANGO2 PF05742.12 EST42114.1 - 0.01 15.9 2.7 0.02 14.9 2.7 1.4 1 0 0 1 1 1 0 Transport and Golgi organisation 2 MetOD1 PF18546.1 EST42114.1 - 0.15 12.0 5.1 2.3 8.1 0.1 2.6 2 0 0 2 2 2 0 Metanogen output domain 1 DUF5602 PF18197.1 EST42115.1 - 0.81 10.2 6.1 19 5.8 1.0 3.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5602) zf-RING_9 PF13901.6 EST42115.1 - 4 7.4 5.5 1.4 8.8 0.5 2.5 3 0 0 3 3 3 0 Putative zinc-RING and/or ribbon SF-assemblin PF06705.11 EST42116.1 - 4.8e-13 49.0 25.8 2.1e-12 47.0 25.8 1.8 1 1 0 1 1 1 1 SF-assemblin/beta giardin Herpes_UL31 PF02718.14 EST42116.1 - 0.0057 15.7 1.7 0.009 15.0 1.2 1.6 1 1 0 1 1 1 1 Herpesvirus UL31-like protein LIP1 PF15904.5 EST42116.1 - 0.026 14.9 0.5 0.069 13.5 0.5 1.8 1 0 0 1 1 1 0 LKB1 serine/threonine kinase interacting protein 1 Formin_GBD_N PF18382.1 EST42116.1 - 0.25 11.8 4.8 0.15 12.5 1.3 2.3 1 1 1 2 2 2 0 Formin N-terminal GTPase-binding domain PMC2NT PF08066.12 EST42116.1 - 5.3 7.8 12.6 6.5 7.5 1.4 3.2 1 1 2 3 3 3 0 PMC2NT (NUC016) domain VPS13 PF16908.5 EST42117.1 - 5.2e-24 85.4 2.2 5.2e-24 85.4 2.2 7.0 7 2 0 7 7 7 2 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 EST42117.1 - 3.9e-19 68.9 3.7 3.9e-19 68.9 3.7 6.3 6 1 1 7 7 7 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 EST42117.1 - 0.00018 21.8 0.0 0.0007 19.9 0.0 2.0 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain DUF3583 PF12126.8 EST42118.1 - 0.024 14.1 0.2 0.033 13.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) DUF2117 PF09890.9 EST42118.1 - 0.035 13.6 0.1 5.7 6.4 0.0 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2117) DUF2240 PF09999.9 EST42118.1 - 0.064 12.9 0.1 1.8 8.2 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2240) BAR_3 PF16746.5 EST42118.1 - 0.25 11.0 5.2 0.47 10.1 0.2 2.1 1 1 1 2 2 2 0 BAR domain of APPL family Misat_Tub_SegII PF10644.9 EST42119.1 - 0.013 15.8 4.8 0.017 15.4 0.3 3.0 3 1 0 3 3 3 0 Misato Segment II tubulin-like domain Tubulin PF00091.25 EST42119.1 - 0.23 11.6 2.0 9.2 6.4 0.1 2.6 1 1 0 2 2 2 0 Tubulin/FtsZ family, GTPase domain DrrA_P4M PF14860.6 EST42119.1 - 1.6 8.6 5.6 0.42 10.5 0.7 2.5 3 0 0 3 3 3 0 DrrA phosphatidylinositol 4-phosphate binding domain Noggin PF05806.12 EST42120.1 - 0.035 14.0 1.6 0.047 13.6 1.6 1.1 1 0 0 1 1 1 0 Noggin PRK PF00485.18 EST42121.1 - 2.4e-41 141.7 0.2 3e-41 141.3 0.2 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family dNK PF01712.19 EST42121.1 - 2.5e-07 30.8 0.2 3.2e-07 30.4 0.2 1.1 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.6 EST42121.1 - 9.4e-07 29.4 0.0 2e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain CoaE PF01121.20 EST42121.1 - 8.2e-06 25.6 0.6 3.7e-05 23.5 0.6 2.0 1 1 0 1 1 1 1 Dephospho-CoA kinase CPT PF07931.12 EST42121.1 - 0.0059 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Cytidylate_kin PF02224.18 EST42121.1 - 0.013 15.2 0.5 1.1 8.9 0.5 2.2 1 1 0 1 1 1 0 Cytidylate kinase Zeta_toxin PF06414.12 EST42121.1 - 0.021 14.1 0.0 0.034 13.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.6 EST42121.1 - 0.059 13.8 1.0 0.57 10.6 1.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.6 EST42121.1 - 0.074 12.8 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system MobB PF03205.14 EST42121.1 - 0.17 11.8 0.1 26 4.7 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF285 PF03382.14 EST42122.1 - 0.012 15.3 0.2 0.019 14.7 0.2 1.3 1 0 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 WD40 PF00400.32 EST42123.1 - 3.3 8.7 12.6 1.2 10.2 0.3 4.7 3 1 1 4 4 4 0 WD domain, G-beta repeat FKBP_C PF00254.28 EST42124.1 - 1.4e-34 118.3 0.0 1.7e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TBCC PF07986.12 EST42125.1 - 7.7e-20 70.8 3.3 1.8e-19 69.6 3.3 1.7 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 EST42125.1 - 0.0071 16.0 3.5 0.0071 16.0 3.5 1.8 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) C terminal HEPN_RES_NTD1 PF18870.1 EST42126.1 - 0.014 15.6 0.3 0.017 15.3 0.3 1.1 1 0 0 1 1 1 0 HEPN/RES N-terminal domain 1 DnaB_2 PF07261.11 EST42128.1 - 0.25 11.1 3.4 1.9 8.3 0.8 3.0 2 0 0 2 2 2 0 Replication initiation and membrane attachment DUF4021 PF13213.6 EST42129.1 - 0.075 13.0 0.5 1 9.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4021) IFT20 PF14931.6 EST42131.1 - 1e-09 38.6 3.2 1.2e-09 38.4 3.2 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 Clat_adaptor_s PF01217.20 EST42132.1 - 1.8e-33 115.5 2.8 2.2e-33 115.2 2.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Copine PF07002.16 EST42133.1 - 1.1e-09 38.1 0.0 1.8e-09 37.4 0.0 1.4 1 1 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 EST42133.1 - 3.5e-05 24.0 0.2 3.5e-05 24.0 0.2 1.7 2 0 0 2 2 2 1 vWA found in TerF C terminus SASA PF03629.18 EST42133.1 - 0.015 15.0 0.4 0.029 14.0 0.1 1.7 2 0 0 2 2 2 0 Carbohydrate esterase, sialic acid-specific acetylesterase GutM PF06923.11 EST42133.1 - 0.17 12.0 0.8 13 5.9 0.0 2.8 2 1 1 3 3 3 0 Glucitol operon activator protein (GutM) SHIPPO-rpt PF07004.12 EST42134.1 - 4.2e-20 71.7 85.1 0.00025 21.8 1.6 12.2 12 0 0 12 12 12 10 Sperm-tail PG-rich repeat Utp11 PF03998.13 EST42135.1 - 1.4e-12 48.1 12.4 2.2e-12 47.5 12.4 1.3 1 1 0 1 1 1 1 Utp11 protein FliD_N PF02465.18 EST42135.1 - 0.32 11.7 5.0 0.76 10.5 0.5 2.2 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF3912 PF13051.6 EST42136.1 - 1.2e-05 25.4 0.3 0.0023 18.2 0.1 3.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3912) KOW PF00467.29 EST42136.1 - 0.001 18.9 11.6 0.0012 18.7 0.0 4.6 6 0 0 6 6 6 2 KOW motif WD40 PF00400.32 EST42137.1 - 3.4 8.7 12.6 1.2 10.2 0.3 4.7 3 1 1 4 4 4 0 WD domain, G-beta repeat IL4 PF00727.18 EST42138.1 - 0.22 11.8 5.2 0.94 9.7 1.4 2.6 1 1 1 2 2 2 0 Interleukin 4 SBDS PF01172.18 EST42141.1 - 1.9e-13 50.3 0.3 1.9e-13 50.3 0.3 2.3 3 1 0 3 3 3 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 EST42141.1 - 0.013 15.5 0.2 0.023 14.7 0.2 1.5 1 1 0 1 1 1 0 SBDS protein C-terminal domain TBCA PF02970.16 EST42144.1 - 3.8e-12 46.4 7.9 4.5e-12 46.1 7.6 1.3 1 1 0 1 1 1 1 Tubulin binding cofactor A DUF2564 PF10819.8 EST42144.1 - 0.049 14.0 6.6 0.3 11.5 1.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2564) DUF4951 PF16309.5 EST42144.1 - 0.13 12.3 0.7 0.2 11.8 0.5 1.6 1 1 0 1 1 1 0 Domian of unknown function (DUF4951) Lactamase_B PF00753.27 EST42145.1 - 3.7e-21 76.0 0.0 4.3e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EST42145.1 - 3.6e-07 29.9 0.0 4.9e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF5492 PF17596.2 EST42146.1 - 0.13 12.7 2.6 3 8.2 2.6 2.3 1 1 0 1 1 1 0 Family of unknown function (DUF5492) SET PF00856.28 EST42148.1 - 2.7e-10 40.9 0.1 3.3e-09 37.3 0.1 2.3 1 1 0 1 1 1 1 SET domain Meckelin PF09773.9 EST42152.1 - 1.8e-21 76.0 11.9 2.3e-14 52.5 0.0 4.2 3 1 0 4 4 4 4 Meckelin (Transmembrane protein 67) POP1 PF06978.11 EST42153.1 - 1.7e-09 38.0 12.7 6.3e-09 36.1 10.1 2.1 1 1 1 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 Chordopox_G2 PF05796.12 EST42154.1 - 0.061 12.8 0.8 0.17 11.3 0.1 1.9 2 0 0 2 2 2 0 Chordopoxvirus protein G2 DUF641 PF04859.12 EST42155.1 - 0.016 15.6 1.9 0.016 15.6 1.9 3.7 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) SF-assemblin PF06705.11 EST42155.1 - 0.073 12.4 33.4 0.088 12.1 33.4 1.0 1 0 0 1 1 1 0 SF-assemblin/beta giardin LMP PF04778.12 EST42155.1 - 0.48 10.3 29.6 0.35 10.8 2.5 2.2 2 0 0 2 2 2 0 LMP repeated region ZnuA PF01297.17 EST42155.1 - 1.1 8.6 9.9 2 7.8 9.9 1.3 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic TCTP PF00838.17 EST42155.1 - 1.2 9.4 9.8 3.5 8.0 4.8 2.5 1 1 0 2 2 2 0 Translationally controlled tumour protein CAP_N PF01213.19 EST42155.1 - 6.3 6.2 11.2 2.9 7.3 8.3 1.7 1 1 1 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Shugoshin_N PF07558.11 EST42156.1 - 1.9 8.4 10.6 1.9 8.4 4.9 2.7 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region tRNA-synt_1c PF00749.21 EST42157.1 - 8.7e-97 323.8 0.0 1.2e-96 323.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EST42157.1 - 2.4e-31 108.9 0.1 5.2e-31 107.9 0.1 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.15 EST42157.1 - 0.0019 18.2 0.0 0.0042 17.1 0.0 1.5 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Pkinase PF00069.25 EST42159.1 - 1.5e-18 67.2 0.0 2e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST42159.1 - 6.6e-12 45.3 0.0 8e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EST42159.1 - 3.6e-07 29.3 0.0 5e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase NAD_synthase PF02540.17 EST42160.1 - 1.9e-37 128.7 0.0 2.1e-37 128.5 0.0 1.0 1 0 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.16 EST42160.1 - 0.034 12.9 0.0 0.05 12.4 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase PAPS_reduct PF01507.19 EST42160.1 - 0.063 13.3 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Peptidase_S49_N PF08496.10 EST42161.1 - 0.17 11.9 8.7 1.3 9.1 0.6 2.7 3 0 0 3 3 3 0 Peptidase family S49 N-terminal DUF3298 PF11738.8 EST42161.1 - 0.24 12.5 1.7 0.81 10.8 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3298) ComGF PF15980.5 EST42161.1 - 0.33 11.3 0.1 0.33 11.3 0.1 2.5 3 0 0 3 3 3 0 Putative Competence protein ComGF EMP24_GP25L PF01105.24 EST42162.1 - 5.4e-07 29.7 0.8 7.3e-07 29.3 0.8 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Pkinase PF00069.25 EST42164.1 - 9.5e-23 80.9 0.0 1.4e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST42164.1 - 3.3e-13 49.5 0.0 4.3e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EST42164.1 - 0.00034 19.5 1.3 0.00047 19.0 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase PGA2 PF07543.12 EST42164.1 - 1.1 9.2 8.2 2.3 8.2 8.2 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 Pyr_redox_dim PF02852.22 EST42166.1 - 0.067 13.5 0.1 0.17 12.2 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain MqsR_toxin PF15723.5 EST42166.1 - 0.069 13.5 0.6 0.44 10.9 0.1 2.2 2 0 0 2 2 2 0 Motility quorum-sensing regulator, toxin of MqsA DUF489 PF04356.12 EST42167.1 - 0.058 13.4 0.2 0.083 12.9 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF489) zf-RING_2 PF13639.6 EST42172.1 - 0.02 15.2 6.1 0.02 15.2 6.1 3.5 3 0 0 3 3 3 0 Ring finger domain DUF87 PF01935.17 EST42172.1 - 0.32 11.0 4.7 0.74 9.9 4.7 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain GNAT_acetyltran PF12746.7 EST42172.1 - 0.49 9.9 4.8 1.1 8.7 4.8 1.7 1 0 0 1 1 1 0 GNAT acetyltransferase HycA_repressor PF11046.8 EST42174.1 - 0.0047 17.1 0.1 0.0082 16.3 0.1 1.4 1 0 0 1 1 1 1 Transcriptional repressor of hyc and hyp operons DUF19 PF01579.18 EST42174.1 - 0.031 14.1 0.1 0.044 13.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF19) CRM1_repeat_2 PF18784.1 EST42176.1 - 8.7e-08 31.7 0.4 8.7e-08 31.7 0.4 2.2 2 0 0 2 2 2 1 CRM1 / Exportin repeat 2 NfrA_C PF13283.6 EST42177.1 - 0.017 14.6 0.3 0.018 14.5 0.3 1.2 1 0 0 1 1 1 0 Bacteriophage N adsorption protein A C-term V-ATPase_G PF03179.15 EST42177.1 - 0.054 14.0 2.5 0.054 14.0 2.5 2.1 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit GRDB PF07355.12 EST42178.1 - 0.14 11.3 3.9 0.18 11.0 3.9 1.2 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) CAC1F_C PF16885.5 EST42178.1 - 0.82 9.3 8.3 0.89 9.2 8.3 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term DUF1043 PF06295.12 EST42178.1 - 3 7.8 22.8 7.1 6.7 21.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) MMR_HSR1 PF01926.23 EST42179.1 - 6.5e-13 48.8 0.0 1.2e-10 41.4 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EST42179.1 - 5.3e-05 22.8 0.1 0.00024 20.7 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EST42179.1 - 0.00023 21.1 0.7 0.75 9.7 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase APH PF01636.23 EST42179.1 - 0.81 9.6 3.1 8.5 6.2 1.3 2.9 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 EST42180.1 - 1.2e-17 64.1 1.2 4.7e-17 62.2 0.0 2.6 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST42180.1 - 4.9e-10 39.1 0.4 2.8e-09 36.7 0.0 2.5 3 0 0 3 3 3 1 Protein tyrosine kinase PAS PF00989.25 EST42180.1 - 0.025 14.6 0.7 0.09 12.8 0.7 1.9 1 0 0 1 1 1 0 PAS fold TSNR_N PF04705.12 EST42180.1 - 0.072 13.2 0.1 0.24 11.5 0.1 1.8 1 0 0 1 1 1 0 Thiostrepton-resistance methylase, N terminus DUF2935 PF11155.8 EST42180.1 - 1.8 8.9 10.1 50 4.3 9.7 3.3 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) Pkinase PF00069.25 EST42181.1 - 2.1e-71 240.4 0.0 5.2e-71 239.1 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST42181.1 - 4.2e-37 127.8 0.1 2.5e-36 125.3 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EST42181.1 - 0.0013 17.7 1.4 0.0032 16.5 1.4 1.6 1 0 0 1 1 1 1 Haspin like kinase domain DUF747 PF05346.11 EST42182.1 - 4.6e-05 23.0 18.0 0.0073 15.8 18.0 2.4 1 1 0 1 1 1 1 Eukaryotic membrane protein family Ank_2 PF12796.7 EST42183.1 - 9.6e-13 48.5 5.9 0.0052 17.4 0.4 4.8 1 1 5 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EST42183.1 - 3.3e-06 27.5 0.0 0.18 12.4 0.1 4.0 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EST42183.1 - 1.4e-05 25.1 0.4 26 5.8 0.0 6.8 7 0 0 7 7 7 0 Ankyrin repeat Ank_5 PF13857.6 EST42183.1 - 4.3e-05 23.7 0.0 2.1 8.8 0.0 4.6 3 1 1 4 4 4 1 Ankyrin repeats (many copies) DUF3447 PF11929.8 EST42183.1 - 0.0043 17.0 1.1 0.0043 17.0 1.1 4.1 2 2 1 3 3 3 1 Domain of unknown function (DUF3447) Ank PF00023.30 EST42183.1 - 0.024 15.1 0.1 23 5.7 0.0 4.3 5 0 0 5 5 5 0 Ankyrin repeat DUF4116 PF13475.6 EST42183.1 - 0.06 13.1 1.9 0.23 11.2 0.5 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4116) WD40 PF00400.32 EST42185.1 - 1.5e-08 35.1 5.5 0.059 14.3 0.1 7.9 9 0 0 9 9 9 1 WD domain, G-beta repeat WD40_like PF17005.5 EST42185.1 - 4.3e-07 29.6 20.5 0.057 12.7 14.7 3.8 1 1 0 2 2 2 2 WD40-like domain Nup160 PF11715.8 EST42185.1 - 1.3e-06 27.3 0.4 0.076 11.6 0.0 3.6 3 1 0 3 3 3 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EST42185.1 - 2.5e-05 24.5 0.3 0.019 15.3 0.0 4.1 4 2 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EST42185.1 - 0.00027 20.9 0.8 1.6 8.8 0.0 4.1 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region RAB3GAP2_N PF14655.6 EST42185.1 - 0.0039 16.5 0.5 0.013 14.8 0.2 2.0 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4520 PF15016.6 EST42185.1 - 0.094 12.8 0.0 0.31 11.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) POLO_box PF00659.18 EST42185.1 - 0.095 12.9 4.6 15 5.9 0.0 4.3 4 0 0 4 4 4 0 POLO box duplicated region DUF4809 PF16067.5 EST42185.1 - 1.4 9.1 5.4 1.8 8.8 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4809) Bromodomain PF00439.25 EST42187.1 - 2.7e-15 56.2 0.5 1.2e-14 54.2 0.1 2.1 2 1 0 2 2 2 1 Bromodomain Ribosomal_S17 PF00366.20 EST42189.1 - 1.1e-26 92.7 2.2 1.7e-26 92.1 2.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_S17_N PF16205.5 EST42189.1 - 1.4e-20 73.4 0.5 1.4e-20 73.4 0.5 1.8 2 0 0 2 2 2 1 Ribosomal_S17 N-terminal OmdA PF13376.6 EST42189.1 - 0.0059 16.6 0.0 0.029 14.4 0.2 1.9 2 0 0 2 2 2 1 Bacteriocin-protection, YdeI or OmpD-Associated MRP-L46 PF11788.8 EST42191.1 - 0.027 15.2 0.2 0.069 13.9 0.2 1.6 1 0 0 1 1 1 0 39S mitochondrial ribosomal protein L46 ADAM_CR PF08516.12 EST42191.1 - 0.4 11.1 3.2 0.45 10.9 1.0 2.0 2 0 0 2 2 2 0 ADAM cysteine-rich Maelstrom PF13017.6 EST42193.1 - 0.00054 19.7 0.8 0.033 13.9 0.4 2.3 2 0 0 2 2 2 2 piRNA pathway germ-plasm component RNase_T PF00929.24 EST42193.1 - 0.009 16.6 0.2 1.3 9.5 0.0 2.2 2 0 0 2 2 2 2 Exonuclease Chordopox_A35R PF05989.12 EST42194.1 - 0.033 14.1 2.0 0.086 12.7 0.4 2.4 2 0 0 2 2 2 0 Chordopoxvirus A35R protein WD40 PF00400.32 EST42195.1 - 4e-08 33.8 0.7 0.026 15.4 0.2 4.5 4 1 0 4 4 4 2 WD domain, G-beta repeat Lectin_C PF00059.21 EST42195.1 - 0.019 15.7 0.1 0.079 13.7 0.0 2.0 2 0 0 2 2 2 0 Lectin C-type domain NIF PF03031.18 EST42197.1 - 7.8e-12 45.2 0.1 1.9e-11 44.0 0.1 1.7 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT_2 PF16589.5 EST42197.1 - 0.0015 18.9 2.1 0.022 15.1 0.3 3.0 1 1 1 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EST42197.1 - 0.0048 17.2 1.1 0.23 11.9 0.0 3.1 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 EST42197.1 - 0.023 15.0 0.2 0.056 13.7 0.2 1.6 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 EST42197.1 - 0.029 14.3 0.0 0.066 13.2 0.0 1.5 1 0 0 1 1 1 0 twin BRCT domain AAA_6 PF12774.7 EST42199.1 - 1.5e-143 477.7 1.5 5.8e-141 469.2 0.3 3.6 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EST42199.1 - 1.6e-107 360.1 15.3 1.6e-107 360.1 15.3 6.3 5 1 1 6 6 2 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 EST42199.1 - 3.8e-82 275.5 0.4 3.8e-82 275.5 0.4 5.3 6 0 0 6 6 5 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 EST42199.1 - 5e-74 248.1 4.6 5e-74 248.1 4.6 7.2 6 1 1 7 7 6 2 ATP-binding dynein motor region Dynein_C PF18199.1 EST42199.1 - 1.4e-69 234.7 0.1 1.4e-69 234.7 0.1 2.5 3 0 0 3 3 2 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 EST42199.1 - 3.4e-55 186.4 3.7 9.1e-48 162.2 0.1 5.4 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EST42199.1 - 8.3e-45 152.5 0.7 8.3e-45 152.5 0.7 2.8 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain DHC_N1 PF08385.12 EST42199.1 - 2e-42 145.6 26.9 2e-42 145.6 26.9 4.6 2 2 0 3 3 2 1 Dynein heavy chain, N-terminal region 1 Dynein_heavy PF03028.15 EST42199.1 - 1.4e-36 125.2 2.3 9e-33 112.9 0.6 4.1 3 0 0 3 3 2 2 Dynein heavy chain region D6 P-loop domain MT PF12777.7 EST42199.1 - 3.5e-34 118.3 7.6 8.1e-34 117.2 7.6 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 EST42199.1 - 3.7e-18 65.8 0.2 1.2e-07 31.8 0.0 6.1 5 0 0 5 5 5 2 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 EST42199.1 - 4.5e-14 52.5 0.1 4.5e-14 52.5 0.1 3.9 4 0 0 4 4 2 1 AAA+ lid domain AAA_16 PF13191.6 EST42199.1 - 1.4e-11 45.1 0.1 0.012 16.0 0.0 6.0 5 0 0 5 5 4 2 AAA ATPase domain AAA_22 PF13401.6 EST42199.1 - 6.5e-11 42.7 6.8 0.0002 21.6 0.0 5.6 6 0 0 6 6 3 3 AAA domain DUF815 PF05673.13 EST42199.1 - 5.8e-10 38.8 1.2 0.045 12.9 0.0 3.9 3 0 0 3 3 3 3 Protein of unknown function (DUF815) AAA PF00004.29 EST42199.1 - 1.5e-08 35.2 12.1 0.25 11.8 0.0 8.6 8 0 0 8 8 7 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EST42199.1 - 8.9e-08 32.8 0.5 1.5 9.4 0.0 6.7 5 0 0 5 5 5 1 AAA domain Dynein_AAA_lid PF17852.1 EST42199.1 - 1.9e-07 31.2 0.4 1.9e-07 31.2 0.4 3.4 3 0 0 3 3 1 1 Dynein heavy chain AAA lid domain FtsK_SpoIIIE PF01580.18 EST42199.1 - 2.9e-06 26.8 2.2 0.12 11.8 0.0 4.3 4 0 0 4 4 4 2 FtsK/SpoIIIE family ABC_tran PF00005.27 EST42199.1 - 3.2e-06 27.7 14.6 0.0011 19.5 0.1 6.1 6 1 0 6 6 3 2 ABC transporter AAA_29 PF13555.6 EST42199.1 - 3.6e-06 26.6 2.1 0.26 11.0 0.0 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EST42199.1 - 1.2e-05 25.3 15.9 0.0013 18.6 0.1 5.2 5 0 0 5 5 3 2 RsgA GTPase MMR_HSR1 PF01926.23 EST42199.1 - 3.4e-05 23.9 0.4 0.059 13.5 0.0 3.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 EST42199.1 - 0.00011 22.4 2.8 0.052 13.8 0.1 3.8 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 EST42199.1 - 0.00023 20.6 0.2 0.032 13.6 0.0 2.9 2 0 0 2 2 2 1 Bacterial TniB protein RNA_helicase PF00910.22 EST42199.1 - 0.00044 20.6 7.9 0.26 11.7 0.1 5.2 5 0 0 5 5 3 1 RNA helicase Zeta_toxin PF06414.12 EST42199.1 - 0.0013 18.0 1.8 0.33 10.2 0.1 3.1 3 0 0 3 3 3 1 Zeta toxin AAA_24 PF13479.6 EST42199.1 - 0.0018 18.1 2.6 9 6.0 0.0 5.0 4 0 0 4 4 4 0 AAA domain SMC_N PF02463.19 EST42199.1 - 0.0036 16.8 1.2 1.6 8.1 0.1 4.4 4 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 EST42199.1 - 0.0074 16.0 0.0 1 9.1 0.0 3.1 2 0 0 2 2 2 1 IstB-like ATP binding protein PRK PF00485.18 EST42199.1 - 0.0083 15.9 0.7 1.2 8.8 0.1 3.5 3 0 0 3 3 2 1 Phosphoribulokinase / Uridine kinase family CbiA PF01656.23 EST42199.1 - 0.011 15.8 0.0 0.16 12.1 0.0 3.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Viral_helicase1 PF01443.18 EST42199.1 - 0.011 15.5 0.1 7.3 6.3 0.0 3.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 EST42199.1 - 0.011 15.9 0.1 1.4 9.1 0.0 3.6 3 0 0 3 3 2 0 AAA domain AAA_19 PF13245.6 EST42199.1 - 0.015 15.6 5.4 1.1 9.6 0.0 4.8 5 0 0 5 5 4 0 AAA domain Dynamin_N PF00350.23 EST42199.1 - 0.016 15.2 1.3 5.1 7.1 0.1 3.7 2 0 0 2 2 2 0 Dynamin family Mg_chelatase PF01078.21 EST42199.1 - 0.026 13.9 1.2 0.69 9.3 0.1 3.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 EST42199.1 - 0.033 13.2 4.0 1.3 8.1 0.1 3.4 3 0 0 3 3 2 0 Type II/IV secretion system protein NACHT PF05729.12 EST42199.1 - 0.039 13.9 0.4 13 5.7 0.1 3.7 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 EST42199.1 - 0.084 12.6 4.5 2 8.1 0.0 4.0 4 0 0 4 4 4 0 AAA domain Glu-tRNAGln PF02686.15 EST42199.1 - 0.15 12.3 0.1 1.4 9.3 0.1 2.8 1 0 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit Ploopntkinase3 PF18751.1 EST42199.1 - 0.17 11.8 0.1 3.7 7.4 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 MeaB PF03308.16 EST42199.1 - 0.17 10.8 0.0 0.71 8.8 0.0 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AMP-binding_C_2 PF14535.6 EST42199.1 - 0.21 11.9 7.1 0.36 11.2 3.3 3.6 2 1 1 3 3 1 0 AMP-binding enzyme C-terminal domain APS_kinase PF01583.20 EST42199.1 - 0.23 11.3 0.8 2.8 7.8 0.1 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase NTP_transferase PF00483.23 EST42199.1 - 0.3 10.6 2.0 1.5 8.3 0.0 3.1 3 0 0 3 3 3 0 Nucleotidyl transferase TrwB_AAD_bind PF10412.9 EST42199.1 - 0.46 9.3 8.2 2.2 7.1 0.0 3.7 4 0 0 4 4 4 0 Type IV secretion-system coupling protein DNA-binding domain TsaE PF02367.17 EST42199.1 - 0.52 10.3 2.8 12 5.9 0.0 3.9 4 0 0 4 4 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 EST42199.1 - 0.8 9.0 7.2 0.22 10.9 0.0 3.7 4 0 0 4 4 2 0 KaiC SOAR PF16533.5 EST42199.1 - 4.6 7.3 6.7 3.1 7.8 2.1 3.3 2 0 0 2 2 1 0 STIM1 Orai1-activating region cobW PF02492.19 EST42199.1 - 4.8 6.7 6.6 16 5.0 0.2 3.2 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 EST42199.1 - 5.6 7.0 10.1 3.3 7.7 0.3 5.4 5 0 0 5 5 2 0 Helicase HerA, central domain Isochorismatase PF00857.20 EST42202.1 - 1.8e-20 73.9 0.1 3.1e-20 73.1 0.1 1.4 1 1 0 1 1 1 1 Isochorismatase family RSN1_TM PF13967.6 EST42203.1 - 0.041 13.6 0.2 0.053 13.3 0.2 1.2 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport WD40 PF00400.32 EST42204.1 - 8.7e-15 54.9 0.1 0.017 16.0 0.0 7.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EST42204.1 - 6.4e-05 23.2 0.0 1.8 8.9 0.0 5.6 5 1 1 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EST42204.1 - 0.0023 16.9 0.0 0.012 14.6 0.0 2.2 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein CarbopepD_reg_2 PF13715.6 EST42204.1 - 0.027 14.5 0.0 0.088 12.8 0.0 1.9 1 0 0 1 1 1 0 CarboxypepD_reg-like domain BLI1 PF17324.2 EST42204.1 - 0.13 13.0 1.6 5.7 7.6 0.3 2.8 2 0 0 2 2 2 0 BLOC-1 interactor 1 MTS PF05175.14 EST42205.1 - 1.9e-15 56.8 0.0 3e-15 56.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EST42205.1 - 1.1e-06 29.3 0.0 2.6e-06 28.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EST42205.1 - 4.2e-05 23.4 0.1 5.3e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EST42205.1 - 0.00024 20.6 0.0 0.00039 19.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EST42205.1 - 0.0014 19.2 0.0 0.0029 18.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EST42205.1 - 0.0026 18.5 0.0 0.0044 17.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EST42205.1 - 0.0026 17.6 0.0 0.005 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EST42205.1 - 0.022 14.7 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 EST42205.1 - 0.023 14.1 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase AdoHcyase_NAD PF00670.21 EST42205.1 - 0.078 13.1 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Ras PF00071.22 EST42207.1 - 2.1e-11 43.7 0.0 2.5e-10 40.2 0.0 2.3 2 0 0 2 2 2 1 Ras family PFU PF09070.11 EST42207.1 - 0.014 15.7 0.0 0.08 13.2 0.0 2.3 2 1 0 2 2 2 0 PFU (PLAA family ubiquitin binding) Roc PF08477.13 EST42207.1 - 0.076 13.2 0.1 1.6 9.0 0.1 2.5 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase SLATT_6 PF18169.1 EST42208.1 - 0.14 11.8 8.8 0.098 12.3 5.7 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 6 zf-C2HE PF16278.5 EST42209.1 - 0.17 12.4 0.9 0.57 10.7 0.1 2.4 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Hira PF07569.11 EST42209.1 - 0.45 10.2 3.5 1.6 8.4 3.4 1.9 1 1 1 2 2 2 0 TUP1-like enhancer of split TMEM154 PF15102.6 EST42211.1 - 0.0074 16.2 1.0 0.0074 16.2 1.0 2.0 2 0 0 2 2 2 1 TMEM154 protein family F5_F8_type_C PF00754.25 EST42211.1 - 0.1 12.7 0.5 0.27 11.3 0.5 1.7 1 0 0 1 1 1 0 F5/8 type C domain DUF4834 PF16118.5 EST42211.1 - 0.11 13.5 0.3 0.11 13.5 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) EphA2_TM PF14575.6 EST42211.1 - 0.12 13.2 0.1 0.31 11.9 0.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2207 PF09972.9 EST42211.1 - 0.13 11.0 1.1 0.26 10.0 1.1 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RIFIN PF02009.16 EST42211.1 - 0.93 9.3 6.9 2.3 8.1 6.8 1.7 1 1 0 1 1 1 0 Rifin Pilin_N PF07790.11 EST42211.1 - 3.1 8.8 7.7 0.58 11.1 0.7 2.9 3 0 0 3 3 3 0 Archaeal Type IV pilin, N-terminal DUF5343 PF17278.2 EST42212.1 - 0.012 15.7 1.9 0.014 15.4 0.9 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5343) Myb_DNA-bind_3 PF12776.7 EST42212.1 - 3.8 8.6 8.0 9.6 7.3 0.1 3.2 2 2 1 3 3 3 0 Myb/SANT-like DNA-binding domain EF-hand_7 PF13499.6 EST42213.1 - 1.6e-16 60.5 1.8 1.3e-10 41.5 3.2 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EST42213.1 - 3e-15 55.8 3.5 3.5e-12 46.0 0.8 3.1 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 EST42213.1 - 1.3e-12 46.3 3.2 5.5e-05 22.4 0.5 3.9 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EST42213.1 - 1.5e-08 33.9 8.2 0.00082 19.1 0.1 4.8 5 1 1 6 6 6 3 EF-hand domain EF-hand_9 PF14658.6 EST42213.1 - 5.4e-07 29.8 0.1 0.00032 20.9 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EST42213.1 - 8.8e-06 25.0 4.3 0.18 11.3 0.1 3.8 4 0 0 4 4 4 2 EF hand POTRA_2 PF08479.11 EST42213.1 - 0.018 14.8 1.0 0.66 9.8 0.0 2.9 3 0 0 3 3 3 0 POTRA domain, ShlB-type HTH_3 PF01381.22 EST42213.1 - 0.037 14.1 0.1 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix EFhand_Ca_insen PF08726.10 EST42213.1 - 0.052 13.6 0.1 0.46 10.6 0.0 2.4 2 1 0 2 2 2 0 Ca2+ insensitive EF hand Phage_holin_6_1 PF09682.10 EST42213.1 - 0.1 13.0 0.1 14 6.2 0.1 3.0 3 0 0 3 3 3 0 Bacteriophage holin of superfamily 6 (Holin_LLH) Zn_ribbon_SprT PF17283.2 EST42214.1 - 0.0041 17.0 0.5 0.007 16.3 0.5 1.4 1 0 0 1 1 1 1 SprT-like zinc ribbon domain DNA_RNApol_7kD PF03604.13 EST42214.1 - 0.013 15.1 5.1 0.013 15.1 5.1 2.5 2 1 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Zn_Tnp_IS1595 PF12760.7 EST42214.1 - 0.031 14.3 0.6 0.049 13.6 0.6 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf_UBZ PF18439.1 EST42214.1 - 0.047 13.3 1.4 2.7 7.7 0.3 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger ZZ PF00569.17 EST42214.1 - 0.052 13.4 4.4 1.1 9.1 1.0 2.1 2 0 0 2 2 2 0 Zinc finger, ZZ type Sgf11 PF08209.11 EST42214.1 - 0.053 13.1 2.6 1.7 8.3 0.2 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) NID PF07292.13 EST42214.1 - 0.12 13.0 0.1 0.13 12.9 0.1 1.1 1 0 0 1 1 1 0 Nmi/IFP 35 domain (NID) MCM_OB PF17207.3 EST42214.1 - 0.13 12.1 3.9 0.13 12.1 3.9 1.0 1 0 0 1 1 1 0 MCM OB domain Rubredoxin_2 PF18073.1 EST42214.1 - 0.18 11.6 0.2 0.18 11.6 0.2 2.1 2 0 0 2 2 2 0 Rubredoxin metal binding domain DUF1242 PF06842.12 EST42215.1 - 2.7e-08 33.5 0.1 4e-08 32.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) FH2 PF02181.23 EST42216.1 - 8.2e-33 114.0 1.2 8.2e-33 114.0 1.2 3.0 3 1 0 3 3 3 1 Formin Homology 2 Domain HTH_19 PF12844.7 EST42216.1 - 0.024 14.6 2.2 0.062 13.3 1.0 2.5 2 1 0 2 2 2 0 Helix-turn-helix domain CIDR1_gamma PF18562.1 EST42216.1 - 2.2 8.4 5.1 0.48 10.6 0.1 2.6 3 0 0 3 3 3 0 Cysteine-Rich Interdomain Region 1 gamma WD40 PF00400.32 EST42217.1 - 2.8e-05 24.8 0.2 5.5 8.0 0.0 5.9 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EST42217.1 - 0.018 15.3 0.0 2.6 8.4 0.0 3.6 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DUF902 PF06001.13 EST42218.1 - 0.29 11.7 1.7 2 9.0 0.1 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF902) LOH1CR12 PF10158.9 EST42218.1 - 8.1 6.5 16.9 1.9 8.5 1.0 4.3 4 0 0 4 4 4 0 Tumour suppressor protein Enolase_C PF00113.22 EST42221.1 - 4.1e-116 387.4 0.3 6.1e-116 386.8 0.3 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EST42221.1 - 1.8e-51 173.8 0.0 3.4e-51 172.8 0.0 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EST42221.1 - 7.2e-07 29.0 0.0 1.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 EST42221.1 - 1.5e-05 24.3 0.1 2.8e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus YlmH_RBD PF17774.1 EST42221.1 - 0.078 13.3 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative RNA-binding domain in YlmH TBCC PF07986.12 EST42222.1 - 9.7e-07 28.5 7.3 2.3e-06 27.3 7.3 1.7 1 0 0 1 1 1 1 Tubulin binding cofactor C SepSecS PF05889.13 EST42223.1 - 0.055 12.2 0.1 0.076 11.7 0.1 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS SecY PF00344.20 EST42224.1 - 3.3e-36 125.1 7.6 3.6e-36 125.0 7.6 1.0 1 0 0 1 1 1 1 SecY translocase SHR3_chaperone PF08229.11 EST42224.1 - 0.0017 17.4 1.9 0.083 11.9 0.4 2.3 2 0 0 2 2 2 2 ER membrane protein SH3 Lyase_catalyt PF09093.11 EST42224.1 - 0.15 11.1 0.1 0.24 10.5 0.1 1.2 1 0 0 1 1 1 0 Lyase, catalytic RICTOR_M PF14666.6 EST42226.1 - 3.4e-05 23.5 3.6 0.00092 19.0 0.3 3.8 1 1 1 2 2 2 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 EST42226.1 - 5.3e-05 23.6 1.3 5.3e-05 23.6 1.3 3.5 2 1 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 EST42226.1 - 0.0025 18.0 1.9 0.015 15.5 0.0 3.3 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 Importin_rep_5 PF18816.1 EST42226.1 - 0.58 10.5 2.9 1.9 8.8 0.1 3.2 3 0 0 3 3 3 0 Importin repeat SecA_DEAD PF07517.14 EST42226.1 - 6.3 6.0 10.4 0.19 11.0 0.1 2.7 2 0 0 2 2 2 0 SecA DEAD-like domain DHHC PF01529.20 EST42227.1 - 1.1e-21 77.3 10.1 1.1e-21 77.3 10.1 2.2 1 1 0 2 2 2 1 DHHC palmitoyltransferase PI3_PI4_kinase PF00454.27 EST42228.1 - 5e-53 180.5 4.4 1.2e-52 179.2 0.5 2.7 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EST42228.1 - 2.4e-17 62.5 0.6 1e-16 60.4 0.6 2.2 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 EST42228.1 - 2.4e-16 59.9 12.8 2.4e-16 59.9 12.8 3.4 3 0 0 3 3 3 1 FAT domain FRB_dom PF08771.11 EST42228.1 - 3.1e-07 30.7 1.1 3.1e-07 30.7 1.1 3.2 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain APH PF01636.23 EST42228.1 - 0.0032 17.4 0.0 0.0065 16.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family HEAT PF02985.22 EST42228.1 - 0.066 13.5 0.0 1.4e+02 3.1 0.0 5.1 6 0 0 6 6 6 0 HEAT repeat Pkinase PF00069.25 EST42230.1 - 3.4e-44 151.2 0.7 5.5e-44 150.5 0.7 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST42230.1 - 7.1e-40 136.9 0.2 9.2e-40 136.5 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EST42230.1 - 0.00022 20.3 1.7 0.0032 16.5 1.7 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EST42230.1 - 0.0021 16.9 0.2 0.0028 16.5 0.2 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EST42230.1 - 0.023 14.1 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EST42230.1 - 0.028 14.3 0.0 4.5 7.1 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 EST42230.1 - 0.047 13.2 0.1 0.4 10.2 0.1 2.0 1 1 1 2 2 2 0 PhoP regulatory network protein YrbL ArsA_HSP20 PF17886.1 EST42231.1 - 0.051 13.1 0.1 0.39 10.3 0.0 2.2 2 0 0 2 2 2 0 HSP20-like domain found in ArsA TCL1_MTCP1 PF01840.17 EST42231.1 - 0.073 12.7 0.2 1.3 8.7 0.0 2.3 1 1 1 2 2 2 0 TCL1/MTCP1 family DUF1525 PF07511.11 EST42231.1 - 0.095 12.8 0.6 0.19 11.9 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1525) VRP3 PF03536.15 EST42232.1 - 0.0039 16.7 1.1 0.0045 16.5 1.1 1.1 1 0 0 1 1 1 1 Salmonella virulence-associated 28kDa protein bZIP_2 PF07716.15 EST42232.1 - 0.1 12.7 4.4 0.18 11.9 0.7 2.4 2 0 0 2 2 2 0 Basic region leucine zipper Viral_P18 PF04521.13 EST42232.1 - 0.11 12.3 0.4 0.19 11.5 0.2 1.5 1 1 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein TatD_DNase PF01026.21 EST42234.1 - 3.3e-37 128.2 0.4 4.1e-37 127.9 0.4 1.1 1 0 0 1 1 1 1 TatD related DNase Aldose_epim PF01263.20 EST42234.1 - 0.017 14.4 0.4 0.064 12.6 0.1 1.9 2 0 0 2 2 2 0 Aldose 1-epimerase Spore_YtrH PF14034.6 EST42234.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Sporulation protein YtrH HECT PF00632.25 EST42236.1 - 1.9e-25 90.0 7.9 1.8e-24 86.8 7.9 1.9 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF3556 PF12077.8 EST42236.1 - 0.13 10.6 0.1 0.2 10.0 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein of unknown function (DUF3556) SecY PF00344.20 EST42237.1 - 5.7e-47 160.5 11.5 7.8e-47 160.0 11.5 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 EST42237.1 - 3.9e-08 33.0 0.1 1.1e-07 31.5 0.1 1.8 1 0 0 1 1 1 1 Plug domain of Sec61p SHR3_chaperone PF08229.11 EST42237.1 - 0.0028 16.7 1.4 0.15 11.0 0.3 2.6 2 0 0 2 2 2 2 ER membrane protein SH3 TAFII55_N PF04658.13 EST42239.1 - 1.8e-07 31.0 0.2 1.2e-06 28.3 0.0 2.0 2 0 0 2 2 2 1 TAFII55 protein conserved region Fmp27_WPPW PF10359.9 EST42239.1 - 0.00028 19.9 1.9 0.00037 19.5 1.9 1.2 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF4175 PF13779.6 EST42239.1 - 1.8 6.4 11.3 2.1 6.1 11.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Ribosomal_S2 PF00318.20 EST42240.1 - 2.9e-24 85.5 1.3 2.8e-12 46.4 0.1 2.6 2 1 1 3 3 3 2 Ribosomal protein S2 DUF3584 PF12128.8 EST42241.1 - 0.19 9.2 38.1 0.23 8.9 38.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1664 PF07889.12 EST42241.1 - 5.3 7.1 26.7 0.31 11.1 11.7 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4200 PF13863.6 EST42241.1 - 9.9 6.6 45.1 0.34 11.3 18.4 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) BRCT PF00533.26 EST42243.1 - 9.5e-08 32.3 0.0 3.9e-07 30.3 0.0 2.2 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Rad17 PF03215.15 EST42243.1 - 1.2e-06 28.6 0.0 4.4e-06 26.7 0.0 2.0 1 1 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 EST42243.1 - 6.4e-06 26.6 0.0 1.8e-05 25.1 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EST42243.1 - 0.00014 22.3 0.0 0.00037 20.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 EST42243.1 - 0.00025 21.1 1.3 0.00048 20.2 0.3 2.0 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EST42243.1 - 0.00094 19.0 0.1 0.0016 18.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EST42243.1 - 0.0011 19.3 0.2 0.29 11.4 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_23 PF13476.6 EST42243.1 - 0.0015 19.1 0.3 0.0015 19.1 0.3 3.1 2 1 1 3 3 2 1 AAA domain AAA_30 PF13604.6 EST42243.1 - 0.0033 17.2 0.0 0.0087 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EST42243.1 - 0.0037 17.8 0.0 0.019 15.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EST42243.1 - 0.005 16.5 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SSE PF00437.20 EST42243.1 - 0.0054 15.8 0.0 0.012 14.7 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein RsgA_GTPase PF03193.16 EST42243.1 - 0.0068 16.3 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase RuvB_N PF05496.12 EST42243.1 - 0.011 15.5 0.0 0.087 12.6 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 EST42243.1 - 0.015 15.1 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 EST42243.1 - 0.017 15.6 2.9 0.058 13.9 0.2 3.0 3 1 0 3 3 3 0 ABC transporter AAA_28 PF13521.6 EST42243.1 - 0.033 14.4 0.0 0.068 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EST42243.1 - 0.041 14.0 0.1 0.14 12.2 0.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 EST42243.1 - 0.057 13.8 1.5 0.12 12.8 0.0 2.4 3 0 0 3 3 1 0 RNA helicase FtsK_SpoIIIE PF01580.18 EST42243.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_19 PF13245.6 EST42243.1 - 0.12 12.7 0.3 0.51 10.7 0.0 2.1 2 1 0 2 2 1 0 AAA domain SMC_N PF02463.19 EST42243.1 - 0.14 11.6 0.5 0.3 10.5 0.3 1.6 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_5 PF07728.14 EST42243.1 - 0.14 12.1 0.0 0.48 10.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) BcrAD_BadFG PF01869.20 EST42244.1 - 1.4e-08 34.6 0.0 2.6e-08 33.7 0.0 1.4 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family ROK PF00480.20 EST42244.1 - 0.0012 18.4 0.1 0.0019 17.7 0.1 1.3 1 0 0 1 1 1 1 ROK family FGGY_N PF00370.21 EST42244.1 - 0.0086 15.7 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Guanylate_cyc PF00211.20 EST42245.1 - 3.3e-13 49.7 0.9 3.9e-12 46.2 0.9 2.1 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase PF00069.25 EST42247.1 - 6.6e-54 183.0 2.5 3.2e-39 134.9 1.3 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EST42247.1 - 7.4e-30 104.1 0.8 8.6e-21 74.4 0.2 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase POLO_box PF00659.18 EST42247.1 - 2e-09 37.5 3.2 1.5e-08 34.7 0.2 3.5 3 0 0 3 3 3 1 POLO box duplicated region Kinase-like PF14531.6 EST42247.1 - 1.4e-08 34.4 0.7 0.067 12.5 0.1 3.5 3 0 0 3 3 3 3 Kinase-like SpoOE-like PF09388.10 EST42247.1 - 0.035 14.0 1.8 0.16 11.9 0.1 2.9 3 0 0 3 3 3 0 Spo0E like sporulation regulatory protein YrbL-PhoP_reg PF10707.9 EST42247.1 - 1.6 8.2 6.3 0.52 9.8 0.1 3.1 4 0 0 4 4 4 0 PhoP regulatory network protein YrbL SHIPPO-rpt PF07004.12 EST42250.1 - 3.5e-07 30.8 33.5 0.00022 22.0 1.5 6.3 6 1 0 6 6 6 3 Sperm-tail PG-rich repeat Pkinase PF00069.25 EST42252.1 - 9.8e-21 74.3 2.1 9.8e-21 74.3 2.1 2.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST42252.1 - 5.4e-13 48.8 0.4 4.6e-12 45.8 0.4 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EST42252.1 - 1.5e-08 34.3 0.6 2.4e-08 33.7 0.6 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EST42252.1 - 0.00043 19.7 0.1 0.00068 19.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family cNMP_binding PF00027.29 EST42254.1 - 5.5e-06 26.4 0.0 0.14 12.2 0.0 3.2 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain Bromodomain PF00439.25 EST42257.1 - 0.0011 19.0 0.6 0.014 15.4 0.2 2.5 1 1 1 2 2 2 1 Bromodomain Snapin_Pallidin PF14712.6 EST42257.1 - 0.037 14.4 1.3 0.14 12.6 0.4 2.2 2 0 0 2 2 2 0 Snapin/Pallidin zf-CCCH PF00642.24 EST42260.1 - 2.1e-05 24.3 6.1 2.1e-05 24.3 6.1 2.4 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EST42260.1 - 0.0004 20.4 6.8 0.0004 20.4 6.8 2.5 2 1 0 2 2 2 1 Zinc finger domain Torus PF16131.5 EST42260.1 - 0.0057 17.3 3.4 0.0057 17.3 3.4 1.6 1 1 1 2 2 2 1 Torus domain GAD-like PF08887.11 EST42260.1 - 0.072 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 GAD-like domain zf-CCCH_4 PF18044.1 EST42260.1 - 0.71 9.7 9.7 0.22 11.4 6.1 2.1 2 0 0 2 2 2 0 CCCH-type zinc finger SHIPPO-rpt PF07004.12 EST42261.1 - 8e-12 45.5 29.2 0.023 15.6 0.1 6.5 6 1 0 6 6 6 6 Sperm-tail PG-rich repeat DUF3536 PF12055.8 EST42262.1 - 0.021 14.2 0.1 0.029 13.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3536) LRR_4 PF12799.7 EST42263.1 - 0.0002 21.7 7.4 0.0002 21.7 7.4 3.8 3 1 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EST42263.1 - 0.019 14.7 6.5 0.11 12.3 6.6 2.2 1 1 0 1 1 1 0 Leucine rich repeat LRR_1 PF00560.33 EST42263.1 - 3 8.7 5.0 2.4e+02 2.9 5.0 3.5 1 1 0 1 1 1 0 Leucine Rich Repeat Leu_zip PF15294.6 EST42265.1 - 0.0028 17.2 8.6 0.0031 17.1 8.6 1.1 1 0 0 1 1 1 1 Leucine zipper CENP-F_leu_zip PF10473.9 EST42265.1 - 0.01 15.9 8.1 0.06 13.4 7.1 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Exonuc_VII_L PF02601.15 EST42265.1 - 1.4 8.4 6.9 2.1 7.9 6.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit ResIII PF04851.15 EST42266.1 - 1.1e-17 64.6 4.6 2e-17 63.7 1.4 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EST42266.1 - 5.4e-10 39.6 0.1 5.4e-10 39.6 0.1 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 EST42266.1 - 2.2e-06 27.6 0.3 8.2e-06 25.7 0.3 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EST42266.1 - 0.00086 19.6 0.5 0.042 14.1 0.0 3.0 3 1 0 3 3 3 1 AAA domain Helicase_C_2 PF13307.6 EST42266.1 - 0.064 13.4 2.7 1.6 8.9 0.1 3.0 1 1 2 3 3 3 0 Helicase C-terminal domain Ribosomal_L12_N PF16320.5 EST42267.1 - 0.0029 17.3 1.1 0.0075 16.0 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain Tli4_N PF18443.1 EST42267.1 - 0.64 10.4 5.4 7.1 7.0 0.1 2.4 2 0 0 2 2 2 0 Tle cognate immunity protein 4 N-terminal domain FlaC_arch PF05377.11 EST42267.1 - 1.1 9.7 9.2 0.36 11.3 3.4 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 EST42267.1 - 3 7.9 9.6 1.9 8.6 4.9 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) ADIP PF11559.8 EST42267.1 - 4.1 7.5 22.2 0.11 12.6 11.4 2.6 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding VASP_tetra PF08776.11 EST42268.1 - 0.037 13.6 1.5 0.18 11.4 0.4 2.8 3 0 0 3 3 3 0 VASP tetramerisation domain Bin3 PF06859.12 EST42269.1 - 1.6 9.4 5.4 1.1 9.9 0.1 2.5 2 0 0 2 2 2 0 Bicoid-interacting protein 3 (Bin3) Cyclin_C PF02984.19 EST42270.1 - 7.6e-23 80.9 2.5 4.5e-21 75.2 0.0 2.7 2 1 1 3 3 3 2 Cyclin, C-terminal domain Cyclin_N PF00134.23 EST42270.1 - 2.6e-22 78.9 1.2 2.8e-20 72.4 0.4 3.0 2 1 0 2 2 2 1 Cyclin, N-terminal domain Lar_restr_allev PF14354.6 EST42270.1 - 0.12 12.8 0.3 7.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Restriction alleviation protein Lar DnaJ_C PF01556.18 EST42271.1 - 1.3e-30 106.5 0.3 2.4e-30 105.6 0.3 1.5 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EST42271.1 - 3.7e-17 62.2 1.2 6.4e-17 61.4 1.2 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EST42271.1 - 1.2e-12 48.0 20.5 3.7e-12 46.4 20.5 1.9 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EST42271.1 - 4.4 7.3 19.2 0.21 11.6 4.2 2.8 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Ank_4 PF13637.6 EST42272.1 - 2.1e-13 50.5 0.8 9.7e-05 22.8 0.1 5.8 6 0 0 6 6 6 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EST42272.1 - 3e-11 43.8 3.3 0.014 16.0 0.0 6.3 7 0 0 7 7 7 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EST42272.1 - 0.00017 21.8 8.1 11 7.0 0.0 7.0 8 0 0 8 8 8 2 Ankyrin repeat Biotin_carb_C PF02785.19 EST42272.1 - 0.045 13.8 3.2 5.6 7.1 0.2 4.1 4 0 0 4 4 4 0 Biotin carboxylase C-terminal domain Ank_5 PF13857.6 EST42272.1 - 0.068 13.5 0.2 35 4.9 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Sda PF08970.10 EST42272.1 - 0.26 11.1 2.2 0.54 10.0 0.4 2.4 2 0 0 2 2 2 0 Sporulation inhibitor A YcgL PF05166.13 EST42272.1 - 3.4 8.1 6.6 11 6.5 0.1 3.8 3 0 0 3 3 3 0 YcgL domain Phage_TAC_6 PF09550.10 EST42274.1 - 0.03 14.7 0.1 0.071 13.6 0.1 1.6 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC YqbF PF14553.6 EST42274.1 - 0.066 13.1 0.6 0.13 12.1 0.6 1.4 1 0 0 1 1 1 0 YqbF, hypothetical protein domain DUF4946 PF16304.5 EST42277.1 - 0.11 12.2 0.1 0.13 12.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4946) AA_permease_N PF08403.10 EST42277.1 - 0.16 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Amino acid permease N-terminal COX6C PF02937.15 EST42278.1 - 0.0058 16.7 0.2 0.0095 16.1 0.2 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIc Glycohydro_20b2 PF14845.6 EST42278.1 - 0.048 14.3 0.4 0.053 14.2 0.4 1.3 1 1 0 1 1 1 0 beta-acetyl hexosaminidase like UQ_con PF00179.26 EST42280.1 - 3.6e-47 159.5 0.0 4.1e-47 159.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EST42280.1 - 0.1 12.9 0.1 0.15 12.4 0.1 1.5 1 1 0 1 1 1 0 RWD domain HTH_46 PF15977.5 EST42282.1 - 0.15 12.1 0.9 0.27 11.3 0.1 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA binding COPI_assoc PF08507.10 EST42284.1 - 0.091 12.8 11.8 0.16 12.0 11.8 1.4 1 0 0 1 1 1 0 COPI associated protein Neur_chan_memb PF02932.16 EST42284.1 - 0.25 11.4 8.2 0.42 10.6 8.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3584 PF12128.8 EST42284.1 - 0.34 8.4 21.5 0.39 8.2 21.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AP1AR PF15745.5 EST42284.1 - 0.62 9.6 18.4 0.84 9.2 18.4 1.2 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein SLC12 PF03522.15 EST42284.1 - 1.9 7.4 10.6 2.3 7.1 10.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DDHD PF02862.17 EST42284.1 - 2.6 8.2 5.6 3.7 7.6 5.6 1.3 1 0 0 1 1 1 0 DDHD domain DUF1682 PF07946.14 EST42284.1 - 5.8 6.0 19.4 8.6 5.5 19.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) TMEM208_SND2 PF05620.11 EST42287.1 - 7e-24 84.5 0.0 8.3e-24 84.3 0.0 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 LRR_6 PF13516.6 EST42288.1 - 0.0096 15.9 0.2 0.11 12.6 0.0 2.4 2 0 0 2 2 2 1 Leucine Rich repeat LRR_1 PF00560.33 EST42288.1 - 0.073 13.7 0.0 3.2 8.7 0.0 2.6 2 0 0 2 2 2 0 Leucine Rich Repeat SLC35F PF06027.12 EST42290.1 - 1.2e-11 44.7 17.0 2e-11 44.0 17.0 1.3 1 1 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 EST42290.1 - 1.7e-06 27.2 4.1 1.7e-06 27.2 4.1 1.8 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 EST42290.1 - 0.0059 16.8 40.6 0.021 15.0 9.1 2.4 2 1 0 2 2 2 2 EamA-like transporter family SRP_TPR_like PF17004.5 EST42292.1 - 2.3e-07 30.9 5.3 2.6e-07 30.7 1.7 2.3 2 0 0 2 2 2 1 Putative TPR-like repeat TPR_1 PF00515.28 EST42292.1 - 6.3e-05 22.6 7.7 0.00039 20.1 3.5 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EST42292.1 - 0.3 11.3 5.6 0.57 10.4 1.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EST42292.1 - 0.47 10.8 6.2 0.72 10.2 1.8 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EST42292.1 - 1.6 9.0 8.3 1.3 9.3 1.5 2.6 1 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Transglut_core PF01841.19 EST42293.1 - 0.0034 17.8 0.0 0.011 16.1 0.0 1.9 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rho_N PF07498.12 EST42293.1 - 0.011 15.6 0.5 0.026 14.5 0.5 1.6 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain PriA_3primeBD PF17764.1 EST42293.1 - 0.061 13.2 0.1 0.51 10.3 0.0 2.3 2 0 0 2 2 2 0 3′ DNA-binding domain (3′BD) Transglut_core PF01841.19 EST42294.1 - 0.0023 18.4 0.0 0.0059 17.1 0.0 1.7 2 0 0 2 2 2 1 Transglutaminase-like superfamily Myb_DNA-binding PF00249.31 EST42295.1 - 7.3e-09 35.7 1.6 1e-08 35.2 1.6 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST42295.1 - 3e-06 27.4 0.6 3.5e-06 27.1 0.6 1.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST42295.1 - 0.0011 18.9 0.1 0.0011 18.8 0.1 1.1 1 0 0 1 1 1 1 Myb DNA-binding like HSL_N PF06350.12 EST42297.1 - 0.069 12.1 1.3 0.091 11.7 1.3 1.2 1 0 0 1 1 1 0 Hormone-sensitive lipase (HSL) N-terminus Cyclin_C PF02984.19 EST42299.1 - 1.3e-05 25.3 0.0 2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 EST42299.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain Aa_trans PF01490.18 EST42300.1 - 2.1e-31 109.0 43.2 2.1e-31 109.0 43.2 1.4 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein PC_rep PF01851.22 EST42301.1 - 0.01 16.2 0.2 0.01 16.2 0.2 3.4 4 0 0 4 4 4 0 Proteasome/cyclosome repeat DUF1290 PF06947.12 EST42301.1 - 0.053 13.6 0.1 0.13 12.4 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1290) Cyt-b5 PF00173.28 EST42302.1 - 5.3e-08 32.9 0.1 7.9e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ELFV_dehydrog PF00208.21 EST42303.1 - 3.2e-79 266.1 0.7 4.2e-79 265.7 0.7 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 EST42303.1 - 3.4e-52 175.8 0.0 7.4e-52 174.7 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain OmpA PF00691.20 EST42304.1 - 0.13 12.6 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 OmpA family RPN1_RPN2_N PF17781.1 EST42306.1 - 4.9e-11 42.6 5.5 1.3e-10 41.2 5.5 1.7 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain PC_rep PF01851.22 EST42306.1 - 2.8e-06 27.5 1.7 0.52 10.8 0.3 4.6 3 0 0 3 3 3 3 Proteasome/cyclosome repeat DUF4170 PF13773.6 EST42307.1 - 3.7e-06 27.0 0.0 84 3.4 0.0 6.7 7 0 0 7 7 7 0 Domain of unknown function (DUF4170) DUF824 PF05688.11 EST42307.1 - 2.9e-05 23.8 10.6 12 5.8 0.1 6.2 6 0 0 6 6 6 3 Salmonella repeat of unknown function (DUF824) Cytochrom_B559a PF00284.20 EST42307.1 - 0.00011 21.8 22.1 5.8 6.8 0.0 7.1 9 0 0 9 9 9 5 Lumenal portion of Cytochrome b559, alpha (gene psbE) subunit AraC_binding_2 PF14525.6 EST42307.1 - 0.013 15.2 0.2 6.1 6.5 0.0 2.8 1 1 2 3 3 3 0 AraC-binding-like domain P19Arf_N PF07392.12 EST42307.1 - 0.22 12.0 16.3 24 5.5 0.3 6.4 1 1 6 7 7 7 0 Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus BH4 PF02180.17 EST42307.1 - 2.5 8.0 6.9 4.5e+02 0.8 0.0 6.2 7 0 0 7 7 7 0 Bcl-2 homology region 4 ELFV_dehydrog PF00208.21 EST42308.1 - 1.8e-79 266.9 0.8 2.3e-79 266.5 0.8 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 EST42308.1 - 3.4e-52 175.8 0.0 7.4e-52 174.7 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain TPH PF13868.6 EST42309.1 - 3.9e-14 51.9 124.4 3.9e-14 51.9 124.4 2.0 2 0 0 2 2 2 1 Trichohyalin-plectin-homology domain GA-like PF17573.2 EST42309.1 - 0.035 14.0 0.5 0.035 14.0 0.5 3.8 4 0 0 4 4 4 0 GA-like domain DUF4548 PF15081.6 EST42309.1 - 0.88 9.4 8.5 0.44 10.4 5.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4548) AAA PF00004.29 EST42311.1 - 2.5e-39 134.7 0.0 4.4e-39 133.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EST42311.1 - 1.4e-10 40.8 0.0 3.3e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EST42311.1 - 1.4e-05 25.3 0.0 2.3e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EST42311.1 - 4.6e-05 23.7 0.9 0.002 18.4 0.9 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EST42311.1 - 0.00021 21.7 0.3 0.0011 19.4 0.3 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 EST42311.1 - 0.0012 18.8 0.0 0.0024 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EST42311.1 - 0.0057 16.4 0.0 0.014 15.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EST42311.1 - 0.0074 16.4 0.2 0.14 12.3 0.1 2.2 1 1 1 2 2 2 1 AAA domain NTPase_1 PF03266.15 EST42311.1 - 0.0079 16.1 0.2 0.022 14.6 0.2 1.9 1 1 0 1 1 1 1 NTPase RuvB_N PF05496.12 EST42311.1 - 0.014 15.1 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 EST42311.1 - 0.016 15.0 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 EST42311.1 - 0.019 14.8 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EST42311.1 - 0.022 14.8 0.1 0.073 13.1 0.1 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EST42311.1 - 0.033 14.7 0.0 0.056 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EST42311.1 - 0.037 14.4 0.0 0.086 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zot PF05707.12 EST42311.1 - 0.058 13.0 0.1 0.28 10.8 0.1 2.0 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) NACHT PF05729.12 EST42311.1 - 0.058 13.3 0.0 1.2 9.1 0.0 2.3 2 0 0 2 2 2 0 NACHT domain DUF815 PF05673.13 EST42311.1 - 0.066 12.4 0.0 0.13 11.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 EST42311.1 - 0.11 12.9 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Cyt-b5 PF00173.28 EST42312.1 - 2.2e-12 46.9 0.7 3.1e-12 46.5 0.7 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TPR_1 PF00515.28 EST42313.1 - 1.3e-11 43.7 16.6 0.024 14.5 0.0 7.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 EST42313.1 - 6.2e-10 38.4 21.3 0.13 12.5 0.0 8.0 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 EST42313.1 - 1.1e-09 37.7 23.5 1.2 9.5 0.2 7.4 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 EST42313.1 - 8.6e-08 32.4 18.0 0.0023 18.2 0.8 6.3 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_6 PF13174.6 EST42313.1 - 6.7e-07 29.5 16.7 2.8 8.8 0.6 8.0 8 0 0 8 8 8 1 Tetratricopeptide repeat DUF5588 PF17826.1 EST42313.1 - 5.9e-06 25.4 0.9 1.2e-05 24.3 0.1 1.9 2 0 0 2 2 2 1 Family of unknown function (DUF5588) TPR_7 PF13176.6 EST42313.1 - 3.5e-05 23.5 13.1 2.3 8.5 0.1 6.7 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 EST42313.1 - 0.0005 20.7 12.1 0.53 11.0 0.1 5.7 3 3 2 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 EST42313.1 - 0.0044 17.5 16.0 3.6 8.2 0.0 5.9 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 EST42313.1 - 0.016 16.0 12.0 7.2 7.7 0.0 6.3 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 EST42313.1 - 0.039 14.3 8.6 7.5 7.2 0.0 5.8 5 1 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EST42313.1 - 0.083 13.1 15.9 0.97 9.7 0.1 4.9 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 EST42313.1 - 0.68 9.9 7.0 64 3.6 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Ribosomal_S13 PF00416.22 EST42314.1 - 6.3e-34 117.1 1.6 7.3e-34 116.9 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 Peptidase_C1 PF00112.23 EST42316.1 - 1.3e-08 35.3 0.0 1.7e-05 25.0 0.0 2.3 2 0 0 2 2 2 2 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EST42316.1 - 0.00019 20.3 0.0 0.0037 16.1 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Forkhead PF00250.18 EST42317.1 - 0.12 12.7 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Forkhead domain Desulfoferrodox PF01880.18 EST42319.1 - 2.7e-12 47.1 0.9 3.5e-12 46.7 0.9 1.2 1 0 0 1 1 1 1 Desulfoferrodoxin Zip PF02535.22 EST42320.1 - 3.4e-14 52.8 1.2 4.1e-14 52.6 1.2 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Phage_holin_3_3 PF16083.5 EST42320.1 - 0.0045 17.1 1.0 0.063 13.4 0.1 2.3 2 0 0 2 2 2 1 LydA holin phage, holin superfamily III DUF2304 PF10066.9 EST42320.1 - 0.057 13.6 2.4 2.5 8.3 0.4 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2304) OPT PF03169.15 EST42320.1 - 0.1 11.2 0.3 0.17 10.5 0.3 1.3 1 0 0 1 1 1 0 OPT oligopeptide transporter protein DUF4006 PF13179.6 EST42320.1 - 5.6 6.9 6.1 3.7 7.5 0.0 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF4006) CBM_20 PF00686.19 EST42321.1 - 5.7e-13 48.6 0.2 2e-11 43.7 0.2 2.6 2 0 0 2 2 2 1 Starch binding domain Glyco_hydro_77 PF02446.17 EST42321.1 - 9.6e-12 44.5 0.0 5.6e-10 38.7 0.0 2.3 2 0 0 2 2 2 2 4-alpha-glucanotransferase Zip PF02535.22 EST42322.1 - 3.2e-15 56.2 0.3 3.9e-15 55.9 0.3 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Phage_holin_3_3 PF16083.5 EST42322.1 - 0.0088 16.1 1.2 0.084 13.0 0.1 2.3 2 0 0 2 2 2 1 LydA holin phage, holin superfamily III DUF2304 PF10066.9 EST42322.1 - 0.099 12.9 2.5 0.89 9.8 2.4 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) OPT PF03169.15 EST42322.1 - 0.15 10.7 0.3 0.24 10.0 0.3 1.3 1 0 0 1 1 1 0 OPT oligopeptide transporter protein ABC_tran PF00005.27 EST42323.1 - 3.7e-12 46.9 0.0 1.6e-11 44.9 0.0 2.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EST42323.1 - 3.8e-05 23.7 0.0 0.037 13.8 0.0 2.7 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 EST42323.1 - 0.022 14.8 0.1 0.061 13.4 0.1 1.7 1 0 0 1 1 1 0 Dynamin family MMR_HSR1 PF01926.23 EST42323.1 - 0.022 14.8 0.0 0.067 13.3 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 EST42323.1 - 0.066 13.0 0.3 0.21 11.4 0.3 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mit_KHE1 PF10173.9 EST42327.1 - 0.051 13.7 0.1 0.064 13.3 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related VSP PF03302.13 EST42328.1 - 0.00017 20.6 6.5 0.00017 20.6 6.5 4.2 1 1 3 4 4 4 3 Giardia variant-specific surface protein DUF3530 PF12048.8 EST42330.1 - 0.036 13.5 0.1 0.036 13.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) VSP PF03302.13 EST42335.1 - 2.2e-07 30.1 35.7 2.2e-07 30.1 35.7 5.0 1 1 4 5 5 5 4 Giardia variant-specific surface protein VSP PF03302.13 EST42336.1 - 4.2e-18 65.4 106.1 7.9e-10 38.1 30.1 5.1 1 1 4 5 5 5 4 Giardia variant-specific surface protein Podoplanin PF05808.11 EST42336.1 - 0.35 11.0 1.8 4 7.5 0.0 2.4 2 0 0 2 2 2 0 Podoplanin DUF4366 PF14283.6 EST42336.1 - 0.68 10.0 5.6 1.1 9.3 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4366) VSP PF03302.13 EST42337.1 - 2.1e-05 23.5 6.5 2.1e-05 23.5 6.5 5.0 1 1 4 5 5 5 3 Giardia variant-specific surface protein DUF4366 PF14283.6 EST42337.1 - 0.36 10.9 0.0 0.36 10.9 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4366) Ribosomal_S4Pg PF11993.8 EST42338.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.0 1 0 0 1 1 1 0 Ribosomal S4P (gammaproteobacterial) CheR_N PF03705.15 EST42341.1 - 0.0013 18.4 0.0 0.0024 17.5 0.0 1.4 1 0 0 1 1 1 1 CheR methyltransferase, all-alpha domain PTPlike_phytase PF14566.6 EST42341.1 - 0.05 13.7 0.7 0.055 13.6 0.7 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate MFS_1 PF07690.16 EST42342.1 - 0.047 12.6 0.8 0.056 12.3 0.8 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily LBP_BPI_CETP PF01273.25 EST42344.1 - 1.7 8.2 7.5 5.3 6.6 7.5 1.8 1 1 0 1 1 1 0 LBP / BPI / CETP family, N-terminal domain Histone PF00125.24 EST42345.1 - 3.6e-31 108.2 4.8 4.3e-31 108.0 4.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EST42345.1 - 3.3e-06 27.2 1.0 5.9e-06 26.4 0.1 1.8 1 1 1 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EST42345.1 - 0.0011 19.3 0.8 0.0018 18.6 0.2 1.6 2 0 0 2 2 2 1 CENP-S protein Nepo_coat_C PF03688.14 EST42345.1 - 0.0086 15.9 0.0 0.01 15.7 0.0 1.1 1 0 0 1 1 1 1 Nepovirus coat protein, C-terminal domain TFIID-31kDa PF02291.15 EST42345.1 - 0.0094 16.0 0.1 0.016 15.3 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit DUF3509 PF12021.8 EST42345.1 - 0.83 9.5 5.0 0.28 10.9 0.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3509) Pkinase PF00069.25 EST42346.1 - 1.1e-17 64.3 1.1 3.9e-09 36.3 0.1 3.3 2 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EST42346.1 - 1.3e-05 24.6 0.0 0.046 13.0 0.0 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase DUF1422 PF07226.11 EST42346.1 - 0.0027 17.7 0.1 0.013 15.5 0.1 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1422) Glyco_hydro_20 PF00728.22 EST42348.1 - 5.1e-10 39.3 0.0 9.6e-08 31.8 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EST42348.1 - 4.3e-05 24.2 0.4 0.00051 20.7 0.1 2.5 1 1 1 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 EST42348.1 - 0.00048 20.9 0.0 0.00096 19.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 ABC_tran PF00005.27 EST42350.1 - 6.1e-10 39.7 0.0 1.8e-09 38.2 0.0 1.7 2 0 0 2 2 2 1 ABC transporter MMR_HSR1 PF01926.23 EST42350.1 - 0.0091 16.1 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EST42350.1 - 0.0096 16.0 0.1 0.016 15.3 0.1 1.3 1 0 0 1 1 1 1 Dynamin family AAA_29 PF13555.6 EST42350.1 - 0.029 14.1 0.5 0.056 13.2 0.5 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EST42350.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_21 PF13304.6 EST42350.1 - 0.15 11.8 0.1 0.41 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Peptidase_M15_2 PF05951.13 EST42352.1 - 0.064 12.9 1.0 0.37 10.4 0.2 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF882) VSP PF03302.13 EST42353.1 - 7.2e-11 41.6 143.5 4.2e-06 25.9 22.3 6.3 2 2 3 5 5 5 4 Giardia variant-specific surface protein Podoplanin PF05808.11 EST42353.1 - 0.074 13.2 0.4 0.13 12.3 0.4 1.4 1 0 0 1 1 1 0 Podoplanin Furin-like_2 PF15913.5 EST42353.1 - 0.25 11.5 130.8 0.061 13.5 8.1 6.8 2 2 4 6 6 6 0 Furin-like repeat, cysteine-rich PARM PF17061.5 EST42353.1 - 3.6 7.7 6.9 0.41 10.7 2.5 1.6 2 0 0 2 2 2 0 PARM VSP PF03302.13 EST42354.1 - 6e-21 74.8 326.8 0.00035 19.6 41.4 11.4 1 1 8 10 10 10 9 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST42354.1 - 0.019 15.1 20.5 0.019 15.1 20.5 11.6 1 1 8 10 10 10 0 Furin-like repeat, cysteine-rich VSP PF03302.13 EST42356.1 - 1.5e-18 66.8 315.1 0.0023 16.9 22.9 10.6 1 1 9 10 10 10 7 Giardia variant-specific surface protein DUF4954 PF16314.5 EST42358.1 - 0.027 12.6 0.4 0.041 12.0 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) VSP PF03302.13 EST42359.1 - 2e-13 50.0 172.0 2.8e-05 23.2 21.9 7.2 1 1 7 8 8 8 6 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST42359.1 - 0.33 11.1 165.3 0.061 13.5 24.1 8.7 1 1 8 9 9 9 0 Furin-like repeat, cysteine-rich PARM PF17061.5 EST42359.1 - 1.5 8.9 5.5 2.3 8.3 5.5 1.2 1 0 0 1 1 1 0 PARM VSP PF03302.13 EST42361.1 - 7.6e-09 34.9 133.6 0.0034 16.3 22.4 6.2 1 1 5 6 6 6 5 Giardia variant-specific surface protein NosD PF05048.13 EST42361.1 - 0.13 11.5 0.9 0.19 11.0 0.9 1.2 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) COE1_DBD PF16422.5 EST42362.1 - 0.054 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Transcription factor COE1 DNA-binding domain VSP PF03302.13 EST42363.1 - 3.1e-16 59.3 358.2 3.4e-05 22.9 22.7 13.2 1 1 9 12 12 12 9 Giardia variant-specific surface protein MFS18 PF17352.2 EST42363.1 - 0.6 10.5 6.7 10 6.6 0.2 3.5 2 1 1 3 3 3 0 Male Flower Specific protein 18 DUF2715 PF10895.8 EST42364.1 - 0.019 14.6 0.4 0.024 14.3 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2715) CobA_CobO_BtuR PF02572.15 EST42367.1 - 0.24 11.6 2.7 3.9 7.7 0.0 2.5 2 0 0 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP DUF1871 PF08958.10 EST42367.1 - 0.49 10.8 3.5 10 6.5 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1871) AAA_assoc_C PF09821.9 EST42369.1 - 0.04 14.5 0.0 0.094 13.3 0.0 1.6 2 0 0 2 2 2 0 C-terminal AAA-associated domain DUF2170 PF09938.9 EST42370.1 - 0.019 14.7 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2170) SMC_N PF02463.19 EST42370.1 - 0.052 13.0 1.1 0.076 12.4 1.1 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain VSP PF03302.13 EST42371.1 - 1.1e-05 24.5 243.9 2.7e-05 23.2 44.6 8.0 1 1 6 7 7 7 6 Giardia variant-specific surface protein DUF2749 PF10907.8 EST42371.1 - 0.057 13.6 1.7 0.15 12.2 1.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) PTP_tm PF18861.1 EST42371.1 - 0.1 12.5 0.5 0.21 11.6 0.5 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Nucleoporin2 PF04096.14 EST42372.1 - 0.0012 19.0 0.1 0.45 10.6 0.0 2.3 1 1 1 2 2 2 2 Nucleoporin autopeptidase DUF3052 PF11253.8 EST42376.1 - 0.15 12.0 0.1 0.32 10.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3052) Sugar_tr PF00083.24 EST42378.1 - 1.9e-58 198.5 36.9 2.7e-39 135.3 13.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EST42378.1 - 5e-17 61.9 61.3 1.6e-14 53.6 35.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EST42378.1 - 0.00016 21.1 6.9 0.00016 21.1 6.9 2.2 1 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB SelK_SelG PF10961.8 EST42378.1 - 1.1 9.9 2.8 1.7 9.3 0.2 2.5 3 0 0 3 3 3 0 Selenoprotein SelK_SelG MASE2 PF05230.11 EST42378.1 - 9.3 6.4 10.5 0.33 11.0 0.4 3.4 3 0 0 3 3 3 0 MASE2 domain VSP PF03302.13 EST42379.1 - 0.012 14.4 57.4 0.04 12.8 8.4 3.0 1 1 2 3 3 3 0 Giardia variant-specific surface protein DUF4366 PF14283.6 EST42379.1 - 0.04 13.9 1.1 0.086 12.9 1.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) RNA_GG_bind PF10258.9 EST42379.1 - 0.042 13.9 0.1 0.092 12.8 0.1 1.6 1 0 0 1 1 1 0 PHAX RNA-binding domain DUF3352 PF11832.8 EST42379.1 - 0.1 11.2 0.1 0.12 11.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3352) Podoplanin PF05808.11 EST42379.1 - 0.65 10.1 4.2 1.1 9.4 4.1 1.5 1 1 0 1 1 1 0 Podoplanin VSP PF03302.13 EST42380.1 - 4.1e-14 52.3 195.8 0.00031 19.7 26.5 7.4 1 1 6 7 7 7 6 Giardia variant-specific surface protein Transgly PF00912.22 EST42383.1 - 0.16 11.4 0.5 11 5.4 0.0 2.6 2 0 0 2 2 2 0 Transglycosylase VSP PF03302.13 EST42385.1 - 7.5e-16 58.0 164.1 4e-06 25.9 22.3 7.0 1 1 5 6 6 6 5 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST42385.1 - 0.0075 16.4 9.6 0.0075 16.4 9.6 8.5 1 1 7 8 8 8 4 Furin-like repeat, cysteine-rich Podoplanin PF05808.11 EST42385.1 - 0.033 14.3 0.1 0.053 13.6 0.1 1.3 1 0 0 1 1 1 0 Podoplanin PARM PF17061.5 EST42385.1 - 0.17 12.0 0.2 0.26 11.4 0.2 1.2 1 0 0 1 1 1 0 PARM VSP PF03302.13 EST42387.1 - 3.6e-13 49.1 130.7 2e-08 33.5 37.0 5.7 1 1 4 5 5 5 5 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST42387.1 - 0.0024 18.0 136.8 0.18 12.0 10.3 9.3 1 1 9 10 10 10 7 Furin-like repeat, cysteine-rich Sigma_1s PF02454.16 EST42389.1 - 0.011 15.7 0.1 0.026 14.5 0.1 1.7 2 0 0 2 2 2 0 Sigma 1s protein UNC45-central PF11701.8 EST42389.1 - 0.028 14.4 0.4 0.042 13.8 0.3 1.3 1 1 0 1 1 1 0 Myosin-binding striated muscle assembly central PAXNEB PF05625.11 EST42389.1 - 0.083 12.0 0.2 0.082 12.0 0.2 1.1 1 0 0 1 1 1 0 PAXNEB protein GMP_synt_C PF00958.22 EST42389.1 - 0.13 12.4 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 GMP synthase C terminal domain VSP PF03302.13 EST42390.1 - 4.6e-06 25.7 90.4 0.00029 19.8 47.6 3.6 1 1 1 2 2 2 2 Giardia variant-specific surface protein cEGF PF12662.7 EST42390.1 - 0.21 11.5 0.4 0.1 12.5 4.6 5.4 6 0 0 6 6 6 0 Complement Clr-like EGF-like TPPK_C PF12555.8 EST42390.1 - 0.27 11.3 1.6 0.41 10.7 1.6 1.2 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal VSP PF03302.13 EST42391.1 - 1.9e-09 36.9 378.2 0.022 13.6 43.0 12.2 1 1 11 12 12 12 10 Giardia variant-specific surface protein TraL PF07178.11 EST42393.1 - 0.02 15.3 0.5 0.031 14.7 0.4 1.5 1 1 0 1 1 1 0 TraL protein Pentapeptide_4 PF13599.6 EST42397.1 - 0.64 10.2 6.3 0.63 10.2 1.9 2.8 3 1 0 3 3 3 0 Pentapeptide repeats (9 copies) Alpha_adaptinC2 PF02883.20 EST42400.1 - 0.015 15.6 0.2 0.068 13.5 0.1 2.0 2 0 0 2 2 2 0 Adaptin C-terminal domain VSP PF03302.13 EST42401.1 - 2.1e-05 23.6 92.6 0.00013 21.0 39.0 3.7 1 1 1 2 2 2 2 Giardia variant-specific surface protein DUF3624 PF12292.8 EST42401.1 - 0.027 14.9 0.3 0.027 14.9 0.3 3.4 5 0 0 5 5 5 0 Protein of unknown function (DUF3624) Podoplanin PF05808.11 EST42401.1 - 0.19 11.8 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Podoplanin VSP PF03302.13 EST42403.1 - 6e-10 38.5 329.1 0.0012 17.8 32.1 10.6 1 1 9 10 10 10 5 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST42403.1 - 0.00033 20.8 18.2 0.00033 20.8 18.2 12.5 1 1 13 14 14 14 3 Furin-like repeat, cysteine-rich cEGF PF12662.7 EST42405.1 - 0.046 13.7 0.4 0.046 13.7 0.4 6.7 7 0 0 7 7 7 0 Complement Clr-like EGF-like VSP PF03302.13 EST42405.1 - 0.4 9.5 101.2 0.5 9.2 31.3 4.9 1 1 2 3 3 3 0 Giardia variant-specific surface protein VSP PF03302.13 EST42408.1 - 4.3e-11 42.3 133.2 0.00085 18.3 34.6 5.1 1 1 3 4 4 4 3 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST42408.1 - 0.0055 16.8 20.6 0.0055 16.8 20.6 5.8 1 1 5 6 6 6 1 Furin-like repeat, cysteine-rich VSP PF03302.13 EST42409.1 - 3.9e-12 45.7 209.3 0.0025 16.7 24.6 7.8 1 1 6 7 7 7 5 Giardia variant-specific surface protein Podoplanin PF05808.11 EST42409.1 - 2.5 8.2 6.2 1 9.5 0.4 2.6 2 0 0 2 2 2 0 Podoplanin HAD_2 PF13419.6 EST42412.1 - 1.7e-21 77.1 0.0 2e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EST42412.1 - 1e-10 42.3 1.7 2.9e-08 34.3 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EST42412.1 - 3.5e-09 37.3 0.3 4.6e-09 37.0 0.3 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EST42412.1 - 0.0031 17.6 0.1 0.0051 16.9 0.1 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like ArfGap PF01412.18 EST42413.1 - 1.7e-32 111.9 3.9 1.7e-32 111.9 3.9 2.5 2 1 1 3 3 3 1 Putative GTPase activating protein for Arf DUF3552 PF12072.8 EST42413.1 - 3.1 7.2 10.2 5.3 6.4 10.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Dpy-30 PF05186.13 EST42414.1 - 1.1e-07 31.4 0.0 1.3e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Dpy-30 motif MHB PF16525.5 EST42415.1 - 0.011 15.9 0.0 0.016 15.5 0.0 1.2 1 0 0 1 1 1 0 Haemophore, haem-binding DUF3199 PF11436.8 EST42415.1 - 0.041 13.9 0.1 0.068 13.2 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3199) RIIa PF02197.17 EST42415.1 - 0.085 12.5 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit DivIC PF04977.15 EST42416.1 - 0.018 14.8 0.6 0.018 14.8 0.6 2.1 3 0 0 3 3 3 0 Septum formation initiator BCAS2 PF05700.11 EST42416.1 - 0.034 13.8 0.9 0.073 12.8 0.9 1.6 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) Peptidase_M15_2 PF05951.13 EST42416.1 - 0.047 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) Sec2p PF06428.11 EST42416.1 - 0.048 13.6 4.6 0.089 12.8 0.3 3.1 3 0 0 3 3 3 0 GDP/GTP exchange factor Sec2p ATG16 PF08614.11 EST42416.1 - 0.056 13.7 1.9 0.072 13.3 0.3 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) SlyX PF04102.12 EST42416.1 - 0.35 11.5 0.2 0.35 11.5 0.2 2.8 4 0 0 4 4 4 0 SlyX CASP_C PF08172.12 EST42416.1 - 0.44 9.9 3.5 0.91 8.8 2.2 2.2 2 1 0 2 2 2 0 CASP C terminal XLF PF09302.11 EST42416.1 - 0.62 10.2 6.6 2.6 8.2 1.2 2.5 1 1 0 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component TMF_DNA_bd PF12329.8 EST42416.1 - 0.84 9.7 8.9 0.069 13.2 2.2 2.6 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF641 PF04859.12 EST42416.1 - 0.96 9.8 4.2 0.96 9.8 1.4 2.3 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) TolA_bind_tri PF16331.5 EST42416.1 - 3.8 7.7 7.1 1 9.5 2.5 2.6 2 1 0 2 2 2 0 TolA binding protein trimerisation Nucleoside_tran PF01733.18 EST42418.1 - 2.6e-21 76.3 20.0 2.6e-21 76.3 20.0 3.2 1 1 1 2 2 2 1 Nucleoside transporter PNTB PF02233.16 EST42418.1 - 0.049 12.5 7.4 0.005 15.8 2.9 1.7 2 0 0 2 2 2 0 NAD(P) transhydrogenase beta subunit zf-LITAF-like PF10601.9 EST42418.1 - 0.064 13.5 0.1 0.064 13.5 0.1 5.6 3 2 1 5 5 5 0 LITAF-like zinc ribbon domain PQ-loop PF04193.14 EST42419.1 - 1.4e-27 95.2 12.7 2.7e-14 52.6 5.2 2.6 2 0 0 2 2 2 2 PQ loop repeat Pkinase PF00069.25 EST42422.1 - 1.3e-58 198.5 0.0 1.8e-58 198.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST42422.1 - 2.9e-28 98.8 0.0 4.5e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EST42422.1 - 9e-07 28.5 0.0 1.9e-05 24.2 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Pkinase_C PF00433.24 EST42422.1 - 1.7e-05 25.4 0.7 5.2e-05 23.9 0.7 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EST42422.1 - 6.3e-05 22.1 0.0 0.0001 21.4 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain I_LWEQ PF01608.17 EST42422.1 - 0.082 13.1 0.0 3.2 8.0 0.1 2.3 2 0 0 2 2 2 0 I/LWEQ domain MORN PF02493.20 EST42423.1 - 2.9e-23 80.3 30.4 4.2e-06 26.3 2.6 7.1 7 0 0 7 7 7 5 MORN repeat RP-C_C PF11800.8 EST42423.1 - 0.51 10.4 3.3 0.69 10.0 3.3 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region PTPRCAP PF15713.5 EST42423.1 - 0.99 9.7 14.4 1.6 9.0 14.4 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated SDA1 PF05285.12 EST42423.1 - 1.2 8.5 14.6 1.5 8.1 14.6 1.1 1 0 0 1 1 1 0 SDA1 Trypan_PARP PF05887.11 EST42423.1 - 2.7 8.0 17.1 4 7.4 17.1 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CDC45 PF02724.14 EST42423.1 - 4.4 5.5 10.1 5.5 5.2 10.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Palm_thioest PF02089.15 EST42424.1 - 1.3e-08 35.0 0.0 1.4e-08 34.9 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase FAINT PF04385.15 EST42426.1 - 0.0043 17.1 1.5 0.39 10.8 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function, DUF529 VSP PF03302.13 EST42427.1 - 0.0029 16.5 29.9 0.0045 15.9 29.9 1.5 1 1 0 1 1 1 1 Giardia variant-specific surface protein DUF4748 PF15932.5 EST42427.1 - 0.12 12.2 0.8 0.22 11.3 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) DUF4366 PF14283.6 EST42427.1 - 0.27 11.3 0.0 0.27 11.3 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) VSP PF03302.13 EST42430.1 - 3.5e-09 36.0 252.0 0.0012 17.8 31.4 8.5 1 1 6 7 7 7 4 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST42430.1 - 0.012 15.8 13.5 0.012 15.8 13.5 10.1 1 1 8 9 9 9 0 Furin-like repeat, cysteine-rich C1ORF64 PF15547.6 EST42434.1 - 0.057 13.9 0.2 0.095 13.2 0.2 1.3 1 0 0 1 1 1 0 Steroid receptor-associated and regulated protein VSP PF03302.13 EST42435.1 - 2.6e-06 26.5 84.6 3.3e-05 22.9 32.9 3.0 1 1 2 3 3 3 2 Giardia variant-specific surface protein Podoplanin PF05808.11 EST42435.1 - 0.068 13.3 2.0 0.1 12.7 1.8 1.4 1 1 0 1 1 1 0 Podoplanin DUF3624 PF12292.8 EST42435.1 - 0.11 13.0 0.2 0.11 13.0 0.2 4.1 4 2 1 5 5 5 0 Protein of unknown function (DUF3624) DUF4530 PF15039.6 EST42437.1 - 0.11 12.6 0.2 0.19 11.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) VSP PF03302.13 EST42439.1 - 0.0012 17.8 86.9 0.0036 16.2 24.6 4.2 1 1 3 4 4 4 2 Giardia variant-specific surface protein Podoplanin PF05808.11 EST42439.1 - 0.64 10.1 7.7 1.3 9.1 0.6 2.3 2 1 0 2 2 2 0 Podoplanin VSP PF03302.13 EST42440.1 - 0.00071 18.5 235.5 0.0037 16.2 64.2 7.9 1 1 5 6 6 6 3 Giardia variant-specific surface protein Insulin_TMD PF17870.1 EST42442.1 - 0.12 12.5 0.1 0.2 11.8 0.1 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF4366 PF14283.6 EST42442.1 - 0.21 11.7 0.0 0.21 11.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) FHIPEP PF00771.20 EST42442.1 - 1.2 7.5 3.1 1.6 7.1 3.1 1.1 1 0 0 1 1 1 0 FHIPEP family VSP PF03302.13 EST42444.1 - 0.0018 17.2 34.9 0.0018 17.2 34.9 4.0 1 1 3 4 4 4 2 Giardia variant-specific surface protein VSP PF03302.13 EST42445.1 - 9.9e-14 51.0 162.3 0.00011 21.2 20.8 7.0 1 1 5 6 6 6 5 Giardia variant-specific surface protein Podoplanin PF05808.11 EST42445.1 - 0.0021 18.2 0.2 0.0035 17.5 0.2 1.3 1 0 0 1 1 1 1 Podoplanin Furin-like_2 PF15913.5 EST42445.1 - 0.024 14.8 11.9 0.024 14.8 11.9 9.1 1 1 8 9 9 9 0 Furin-like repeat, cysteine-rich TctA PF01970.16 EST42445.1 - 0.063 12.0 0.0 0.086 11.5 0.0 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family VSP PF03302.13 EST42446.1 - 5.5e-07 28.8 256.6 6.5e-05 22.0 23.4 10.4 1 1 9 10 10 10 7 Giardia variant-specific surface protein Podoplanin PF05808.11 EST42446.1 - 0.056 13.6 0.3 0.26 11.4 0.1 2.1 2 0 0 2 2 2 0 Podoplanin DiS_P_DiS PF06750.13 EST42447.1 - 0.022 14.9 0.1 0.047 13.8 0.1 1.6 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain Rol_Rep_N PF18106.1 EST42447.1 - 0.11 12.8 0.7 0.27 11.5 0.1 1.9 1 1 1 2 2 2 0 Rolling Circle replication initiation protein N-terminal domain Insulin_TMD PF17870.1 EST42448.1 - 0.12 12.5 0.1 0.2 11.8 0.1 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF4366 PF14283.6 EST42448.1 - 0.2 11.7 0.0 0.2 11.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) FHIPEP PF00771.20 EST42448.1 - 1.2 7.5 3.1 1.6 7.1 3.1 1.1 1 0 0 1 1 1 0 FHIPEP family VSP PF03302.13 EST42449.1 - 0.004 16.1 4.5 0.004 16.1 4.5 2.5 1 1 1 2 2 2 1 Giardia variant-specific surface protein DUF4366 PF14283.6 EST42449.1 - 0.02 15.0 0.6 0.024 14.7 0.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Meckelin PF09773.9 EST42449.1 - 0.29 9.2 1.9 0.39 8.7 1.9 1.2 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) DUF4690 PF15756.5 EST42449.1 - 0.31 11.7 1.3 0.48 11.0 0.7 1.6 1 1 0 2 2 2 0 Small Novel Rich in Cartilage Podoplanin PF05808.11 EST42449.1 - 0.56 10.3 3.1 0.79 9.8 3.0 1.4 1 1 0 1 1 1 0 Podoplanin VSP PF03302.13 EST42450.1 - 2.4e-06 26.7 16.2 3.6e-06 26.1 16.2 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein HSNSD PF12062.8 EST42450.1 - 0.092 11.4 0.1 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 heparan sulfate-N-deacetylase Palm_thioest PF02089.15 EST42452.1 - 3e-26 92.8 0.0 3.3e-26 92.6 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase LIDHydrolase PF10230.9 EST42452.1 - 0.011 15.3 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_1 PF00561.20 EST42452.1 - 0.09 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold LCAT PF02450.15 EST42452.1 - 0.14 11.3 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF3089 PF11288.8 EST42452.1 - 0.17 11.4 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) PE-PPE PF08237.11 EST42452.1 - 0.18 11.4 0.0 0.21 11.1 0.0 1.1 1 0 0 1 1 1 0 PE-PPE domain Endonuclease_1 PF04231.13 EST42453.1 - 1.4e-27 96.9 6.0 2e-27 96.4 6.0 1.1 1 0 0 1 1 1 1 Endonuclease I DUF1524 PF07510.11 EST42453.1 - 0.0055 16.6 1.8 0.0096 15.8 1.7 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1524) Myb_DNA-binding PF00249.31 EST42454.1 - 4.7e-05 23.5 0.5 8.9e-05 22.6 0.1 1.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST42454.1 - 0.00022 21.1 2.5 0.00038 20.3 2.5 1.4 1 1 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 EST42454.1 - 0.00093 19.4 1.2 0.0015 18.8 1.2 1.5 1 1 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EST42454.1 - 0.00099 19.3 3.5 0.0015 18.6 1.0 2.0 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 SseB_C PF14581.6 EST42456.1 - 0.0079 16.3 0.0 0.032 14.3 0.0 2.1 1 0 0 1 1 1 1 SseB protein C-terminal domain DUF3452 PF11934.8 EST42456.1 - 0.23 11.0 4.8 1.6 8.3 0.2 3.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3452) APOBEC4 PF18775.1 EST42457.1 - 0.096 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 APOBEC4 DHHC PF01529.20 EST42459.1 - 2.2e-11 44.0 10.4 3.4e-11 43.4 10.4 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase CSG2 PF16965.5 EST42459.1 - 0.0096 14.9 4.0 0.013 14.5 4.0 1.1 1 0 0 1 1 1 1 Ceramide synthase regulator DUF421 PF04239.12 EST42459.1 - 0.052 13.3 0.1 0.089 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF421) Pro_isomerase PF00160.21 EST42462.1 - 7.7e-06 26.3 0.0 1.3e-05 25.5 0.0 1.3 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Myb_DNA-binding PF00249.31 EST42463.1 - 4.2e-09 36.5 0.2 6.8e-09 35.8 0.2 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST42463.1 - 4.8e-08 32.8 3.4 7.7e-08 32.1 3.4 1.3 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 EST42463.1 - 2e-05 24.8 0.9 4.1e-05 23.7 0.9 1.6 1 1 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EST42463.1 - 0.0057 16.8 1.0 0.012 15.8 1.0 1.6 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Ank_4 PF13637.6 EST42464.1 - 0.0087 16.6 0.1 0.041 14.5 0.0 2.0 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EST42464.1 - 0.021 15.2 0.0 0.054 14.0 0.0 1.7 2 0 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.7 EST42464.1 - 0.038 14.6 0.0 0.078 13.6 0.0 1.6 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EST42464.1 - 0.05 14.2 0.1 0.27 11.9 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat Ank_5 PF13857.6 EST42464.1 - 0.15 12.4 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (many copies) VSP PF03302.13 EST42465.1 - 0.0042 16.0 112.5 0.005 15.7 47.6 4.8 1 1 3 4 4 4 3 Giardia variant-specific surface protein Glucokinase PF02685.16 EST42466.1 - 1.4e-38 132.7 0.0 1.7e-38 132.4 0.0 1.0 1 0 0 1 1 1 1 Glucokinase ROK PF00480.20 EST42466.1 - 2.7e-08 33.6 0.1 5e-08 32.8 0.1 1.4 1 1 0 1 1 1 1 ROK family DUF604 PF04646.12 EST42468.1 - 0.0036 16.7 0.1 0.0047 16.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 LIP PF03583.14 EST42468.1 - 0.051 12.9 0.6 0.06 12.7 0.6 1.0 1 0 0 1 1 1 0 Secretory lipase V-ATPase_C PF03223.15 EST42468.1 - 0.079 12.4 0.4 0.09 12.2 0.4 1.1 1 0 0 1 1 1 0 V-ATPase subunit C LUC7 PF03194.15 EST42468.1 - 0.1 12.2 2.6 0.12 12.0 2.6 1.1 1 0 0 1 1 1 0 LUC7 N_terminus mTERF PF02536.14 EST42468.1 - 0.11 11.3 0.1 0.13 11.2 0.1 1.1 1 0 0 1 1 1 0 mTERF LepB_N PF18640.1 EST42468.1 - 0.17 11.5 1.8 0.66 9.6 0.5 2.0 2 0 0 2 2 2 0 LepB N-terminal domain IL5 PF02025.15 EST42469.1 - 0.055 13.7 0.2 0.1 12.9 0.2 1.4 1 0 0 1 1 1 0 Interleukin 5 Recep_L_domain PF01030.24 EST42470.1 - 0.0029 17.7 0.1 0.021 15.0 0.0 2.0 2 0 0 2 2 2 1 Receptor L domain GST_C PF00043.25 EST42470.1 - 0.0094 16.2 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain VSP PF03302.13 EST42471.1 - 0.00018 20.5 12.8 0.00018 20.5 12.8 2.2 1 1 1 2 2 2 1 Giardia variant-specific surface protein Podoplanin PF05808.11 EST42471.1 - 0.0034 17.5 0.1 0.0065 16.6 0.1 1.4 1 0 0 1 1 1 1 Podoplanin DUF4366 PF14283.6 EST42471.1 - 0.14 12.2 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) SseB_C PF14581.6 EST42475.1 - 0.0082 16.2 0.0 0.032 14.3 0.0 2.0 1 0 0 1 1 1 1 SseB protein C-terminal domain DUF3452 PF11934.8 EST42475.1 - 0.21 11.1 4.5 1.8 8.1 0.2 3.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3452) Ribosomal_L20 PF00453.18 EST42475.1 - 0.33 11.1 1.7 0.62 10.2 0.3 2.3 2 1 0 2 2 2 0 Ribosomal protein L20 VSP PF03302.13 EST42476.1 - 1.1e-08 34.4 100.5 0.0006 18.8 17.5 4.4 1 1 3 4 4 4 4 Giardia variant-specific surface protein Podoplanin PF05808.11 EST42476.1 - 0.13 12.4 0.8 0.27 11.3 0.3 1.8 2 0 0 2 2 2 0 Podoplanin VSP PF03302.13 EST42477.1 - 0.0022 16.9 50.8 0.0039 16.1 15.5 3.1 1 1 2 3 3 3 3 Giardia variant-specific surface protein MPS-4 PF17523.2 EST42477.1 - 0.084 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 Myb_DNA-binding PF00249.31 EST42478.1 - 1.2e-23 83.0 2.0 3.5e-14 52.7 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST42478.1 - 3.7e-22 78.3 1.7 2.1e-14 53.5 0.2 2.5 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 EST42478.1 - 3.3e-07 30.3 0.8 0.013 15.5 0.4 2.2 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_4 PF13837.6 EST42478.1 - 0.0015 18.8 4.9 0.48 10.8 0.2 3.1 2 2 0 2 2 2 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST42478.1 - 0.14 12.1 1.2 1.4 8.8 0.0 2.7 3 0 0 3 3 3 0 Myb DNA-binding like DcrB PF08786.11 EST42478.1 - 0.14 12.2 3.5 0.24 11.5 3.5 1.4 1 0 0 1 1 1 0 DcrB Rap1_C PF11626.8 EST42478.1 - 0.49 10.5 2.5 3 8.0 0.6 2.3 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain ANAPC15 PF15243.6 EST42479.1 - 0.11 13.0 1.1 0.18 12.2 1.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 PNP_UDP_1 PF01048.20 EST42483.1 - 1.4e-26 93.2 0.0 1.3e-25 90.0 0.0 2.2 2 0 0 2 2 2 1 Phosphorylase superfamily TerC PF03741.16 EST42483.1 - 0.043 13.5 0.2 0.11 12.1 0.2 1.7 2 0 0 2 2 2 0 Integral membrane protein TerC family DUF5041 PF16444.5 EST42484.1 - 0.00047 20.5 0.7 0.00094 19.5 0.3 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF5041) Methyltransf_32 PF13679.6 EST42485.1 - 2.8e-18 66.4 0.8 3.9e-17 62.7 0.8 2.2 1 1 0 1 1 1 1 Methyltransferase domain TRM13 PF05206.14 EST42485.1 - 0.015 14.8 0.4 0.033 13.7 0.0 1.8 2 1 0 2 2 2 0 Methyltransferase TRM13 Las1 PF04031.13 EST42486.1 - 2.4e-09 37.5 0.0 4.2e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Las1-like Herpes_UL47 PF03362.13 EST42487.1 - 0.031 13.1 1.4 0.033 13.0 1.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL47 protein FCH PF00611.23 EST42487.1 - 1.1 9.6 5.6 9 6.7 5.6 2.3 1 1 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain CheZ PF04344.13 EST42489.1 - 0.00045 20.2 8.1 0.00045 20.2 8.1 1.9 1 1 1 2 2 2 1 Chemotaxis phosphatase, CheZ Casc1_N PF15927.5 EST42489.1 - 0.013 15.3 5.4 0.013 15.3 5.4 2.0 1 1 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus DUF1048 PF06304.11 EST42489.1 - 0.019 15.4 5.0 0.31 11.5 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1048) Mit_KHE1 PF10173.9 EST42489.1 - 0.076 13.1 2.8 0.091 12.8 2.8 1.2 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related SKICH PF17751.1 EST42489.1 - 0.1 13.2 3.3 0.53 10.9 0.4 2.3 2 0 0 2 2 2 0 SKICH domain ZapD PF07072.11 EST42489.1 - 0.13 12.0 8.8 0.15 11.8 2.3 2.2 1 1 1 2 2 2 0 Cell division protein zf-3CxxC PF13695.6 EST42489.1 - 0.18 12.3 6.9 0.058 13.9 3.4 1.9 1 1 1 2 2 2 0 Zinc-binding domain DUF2400 PF09674.10 EST42489.1 - 0.43 10.5 7.2 1.4 8.9 7.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2400) Phage_lysozyme2 PF18013.1 EST42489.1 - 0.67 10.0 3.9 1.9 8.5 3.8 1.9 1 1 0 1 1 1 0 Phage tail lysozyme Atypical_Card PF18461.1 EST42489.1 - 0.71 10.1 5.4 0.62 10.3 0.4 2.7 2 1 1 3 3 3 0 Atypical caspase recruitment domain FUSC-like PF12805.7 EST42489.1 - 1.3 8.0 10.1 3 6.9 10.1 1.7 1 1 0 1 1 1 0 FUSC-like inner membrane protein yccS DUF948 PF06103.11 EST42489.1 - 1.7 9.0 7.1 32 4.9 1.1 2.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4407 PF14362.6 EST42489.1 - 3.3 7.0 7.3 6.7 6.0 6.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Jnk-SapK_ap_N PF09744.9 EST42489.1 - 4.7 7.4 18.4 23 5.2 2.9 2.9 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 APG6_N PF17675.1 EST42489.1 - 7.7 7.0 19.9 15 6.1 18.7 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region Acetyltransf_7 PF13508.7 EST42491.1 - 0.027 14.9 0.3 0.091 13.2 0.1 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EST42491.1 - 0.073 13.0 0.3 0.53 10.2 0.1 2.3 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain VSP PF03302.13 EST42493.1 - 1.6e-09 37.1 104.1 0.00037 19.5 1.4 5.0 2 1 3 5 5 5 5 Giardia variant-specific surface protein DUF4190 PF13828.6 EST42494.1 - 0.033 13.9 0.1 0.063 13.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4190) NifU PF01106.17 EST42494.1 - 0.15 12.2 0.0 0.43 10.8 0.0 1.7 1 0 0 1 1 1 0 NifU-like domain CAP_assoc_N PF14504.6 EST42494.1 - 1.4 8.6 8.6 0.24 11.1 1.3 2.7 3 0 0 3 3 3 0 CAP-associated N-terminal DUF4251 PF14059.6 EST42494.1 - 3 7.8 10.5 0.43 10.5 0.5 3.6 4 1 0 4 4 4 0 Domain of unknown function (DUF4251) NGF PF00243.18 EST42496.1 - 0.072 13.3 0.1 0.089 13.1 0.1 1.3 1 0 0 1 1 1 0 Nerve growth factor family Pkinase PF00069.25 EST42497.1 - 2.6e-22 79.5 3.1 2.1e-21 76.5 3.1 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST42497.1 - 2.7e-12 46.5 0.6 7.7e-12 45.0 0.1 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EST42497.1 - 1.5e-05 24.5 0.0 1.5e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 Kinase-like BBS2_N PF14781.6 EST42497.1 - 0.0093 15.9 2.2 0.022 14.6 0.3 2.7 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, N-terminal Senescence PF06911.12 EST42497.1 - 4.2 7.6 9.2 3.2 8.0 0.5 2.4 2 0 0 2 2 2 0 Senescence-associated protein ANAPC4_WD40 PF12894.7 EST42498.1 - 1.1e-08 35.3 0.0 0.0085 16.4 0.0 3.9 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EST42498.1 - 6.9e-08 33.0 7.7 0.0047 17.7 0.1 5.8 5 1 0 5 5 5 2 WD domain, G-beta repeat WD40_like PF17005.5 EST42498.1 - 0.0016 17.8 0.2 0.014 14.8 0.1 2.4 2 1 0 2 2 2 1 WD40-like domain DUF1358 PF07096.11 EST42500.1 - 0.062 13.3 1.0 0.12 12.4 0.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1358) NHL PF01436.21 EST42501.1 - 7.5e-12 44.6 1.3 0.00065 19.6 0.3 5.6 5 0 0 5 5 5 4 NHL repeat SGL PF08450.12 EST42501.1 - 0.012 15.3 0.0 4.1 6.9 0.0 2.7 3 0 0 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region Annexin PF00191.20 EST42502.1 - 0.018 15.1 1.4 0.59 10.2 0.1 3.0 3 0 0 3 3 3 0 Annexin TAP42 PF04177.12 EST42503.1 - 1.8e-15 56.9 24.4 6.1e-13 48.6 10.6 2.1 2 0 0 2 2 2 2 TAP42-like family Vert_HS_TF PF06546.11 EST42503.1 - 0.18 11.4 1.8 0.3 10.7 1.8 1.3 1 0 0 1 1 1 0 Vertebrate heat shock transcription factor DUF4061 PF13270.6 EST42503.1 - 0.63 10.4 4.7 0.36 11.2 1.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) DUF3597 PF12200.8 EST42503.1 - 0.82 10.2 3.6 3.1 8.4 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) Ank_2 PF12796.7 EST42504.1 - 9.4e-05 22.9 0.1 0.0017 18.9 0.0 3.2 4 1 0 4 4 4 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EST42504.1 - 0.0031 17.9 0.2 2.5 8.9 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 EST42504.1 - 0.046 14.3 0.2 0.4 11.3 0.1 2.7 2 1 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 EST42504.1 - 0.14 12.7 1.1 3.5 8.3 0.0 3.5 4 0 0 4 4 4 0 Ankyrin repeat DUF2935 PF11155.8 EST42504.1 - 9.3 6.6 8.7 15 6.0 0.0 4.5 3 2 1 4 4 4 0 Domain of unknown function (DUF2935) WD40 PF00400.32 EST42505.1 - 1.2e-44 149.3 16.3 7.2e-09 36.1 0.0 8.6 9 0 0 9 9 9 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EST42505.1 - 6.5e-19 68.0 0.1 0.00017 21.8 0.0 5.8 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EST42505.1 - 1.5e-10 40.9 0.0 6.7e-06 25.6 0.0 3.0 3 1 0 3 3 3 2 WD40-like domain eIF2A PF08662.11 EST42505.1 - 4.4e-06 26.7 0.1 0.002 18.1 0.0 2.5 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A NLE PF08154.12 EST42505.1 - 5.8e-06 26.7 0.9 1.4e-05 25.5 0.8 1.7 2 0 0 2 2 2 1 NLE (NUC135) domain Ge1_WD40 PF16529.5 EST42505.1 - 6.6e-05 22.0 3.0 0.013 14.5 0.0 4.4 2 2 4 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 EST42505.1 - 0.00062 19.2 0.3 0.38 10.0 0.0 3.3 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Argos PF11581.8 EST42505.1 - 0.047 13.7 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Antagonist of EGFR signalling, Argos Cytochrom_D1 PF02239.16 EST42505.1 - 0.086 11.3 0.0 22 3.4 0.0 3.0 3 0 0 3 3 3 0 Cytochrome D1 heme domain DUF948 PF06103.11 EST42506.1 - 0.43 10.9 3.5 0.18 12.1 0.7 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Repressor_Mnt PF11423.8 EST42507.1 - 0.011 15.4 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Regulatory protein Mnt Hce2 PF14856.6 EST42507.1 - 0.066 13.5 0.1 0.081 13.2 0.1 1.2 1 0 0 1 1 1 0 Pathogen effector; putative necrosis-inducing factor CutA1 PF03091.15 EST42507.1 - 0.069 13.0 0.1 0.092 12.6 0.1 1.2 1 0 0 1 1 1 0 CutA1 divalent ion tolerance protein Prefoldin PF02996.17 EST42508.1 - 7e-07 29.2 0.2 9.1e-07 28.8 0.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit Siah-Interact_N PF09032.11 EST42508.1 - 0.27 11.6 3.3 1.7 9.0 1.1 2.3 2 1 0 2 2 2 0 Siah interacting protein, N terminal AAA_14 PF13173.6 EST42509.1 - 2.4 8.2 8.0 0.38 10.8 1.7 2.4 2 1 0 2 2 2 0 AAA domain tRNA_bind PF01588.20 EST42510.1 - 5.1e-16 58.6 0.0 1.1e-15 57.5 0.0 1.6 2 0 0 2 2 2 1 Putative tRNA binding domain HU-CCDC81_euk_2 PF18289.1 EST42511.1 - 0.012 15.8 3.0 0.023 14.8 2.3 1.7 1 1 1 2 2 2 0 CCDC81 eukaryotic HU domain 2 Phage_Coat_B PF05356.11 EST42511.1 - 0.077 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Phage Coat protein B Putative_PNPOx PF01243.20 EST42512.1 - 0.04 14.1 0.0 0.059 13.6 0.0 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase EVE PF01878.18 EST42513.1 - 0.0003 20.8 0.0 0.012 15.6 0.0 2.1 1 1 0 1 1 1 1 EVE domain Bac_small_YrzI PF09501.10 EST42513.1 - 0.096 12.8 0.5 7.8 6.7 0.1 2.5 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) Laminin_G_3 PF13385.6 EST42514.1 - 0.032 14.4 0.1 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 Concanavalin A-like lectin/glucanases superfamily SWIRM-assoc_2 PF16496.5 EST42517.1 - 0.065 12.1 0.0 0.12 11.2 0.0 1.3 2 0 0 2 2 2 0 SWIRM-associated domain at the N-terminal Nup54_57_C PF18570.1 EST42518.1 - 0.031 13.9 15.8 0.13 11.9 0.0 5.3 5 0 0 5 5 5 0 NUP57/Nup54 C-terminal domain YhzD PF14120.6 EST42520.1 - 0.045 13.9 0.1 0.1 12.7 0.1 1.5 1 0 0 1 1 1 0 YhzD-like protein EVE PF01878.18 EST42523.1 - 0.0003 20.8 0.0 0.012 15.6 0.0 2.1 1 1 0 1 1 1 1 EVE domain Bac_small_YrzI PF09501.10 EST42523.1 - 0.096 12.8 0.5 7.8 6.7 0.1 2.5 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) Putative_PNPOx PF01243.20 EST42524.1 - 0.039 14.1 0.0 0.059 13.6 0.0 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase DUF743 PF05332.11 EST42525.1 - 0.2 11.7 1.3 1 9.4 0.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF743) FAM184 PF15665.5 EST42528.1 - 0.00066 19.5 13.3 0.00066 19.5 13.3 2.9 1 1 0 2 2 2 1 Family with sequence similarity 184, A and B DUF5315 PF17242.2 EST42528.1 - 0.0098 15.7 8.6 0.044 13.6 0.3 3.3 3 0 0 3 3 3 1 Disordered region of unknown function (DUF5315) TMF_DNA_bd PF12329.8 EST42528.1 - 0.06 13.4 10.3 0.66 10.0 4.5 3.5 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding CBM27 PF09212.10 EST42528.1 - 0.18 12.0 0.0 0.31 11.3 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate binding module 27 HALZ PF02183.18 EST42528.1 - 0.59 10.4 10.4 2 8.7 1.2 3.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper Prefoldin PF02996.17 EST42528.1 - 6.4 6.7 18.2 1.2 9.0 2.9 4.0 3 1 1 4 4 4 0 Prefoldin subunit LRR_6 PF13516.6 EST42529.1 - 1.1e-09 37.5 15.1 0.00049 19.9 0.1 5.8 6 0 0 6 6 6 4 Leucine Rich repeat LRR_4 PF12799.7 EST42529.1 - 0.73 10.4 22.2 10 6.7 0.0 5.3 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) Pkinase PF00069.25 EST42530.1 - 2e-18 66.7 0.4 1.1e-17 64.3 0.4 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST42530.1 - 6.7e-10 38.7 0.4 3.2e-09 36.5 0.4 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase DSPc PF00782.20 EST42530.1 - 6.9e-05 22.7 1.4 0.00026 20.8 0.2 2.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain zf-CCHC_2 PF13696.6 EST42530.1 - 0.097 12.5 0.3 0.21 11.4 0.3 1.6 1 0 0 1 1 1 0 Zinc knuckle DnaJ PF00226.31 EST42533.1 - 0.0027 17.8 0.1 0.006 16.7 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain CRA PF06589.11 EST42534.1 - 0.0089 16.1 5.9 0.18 11.9 1.1 2.4 2 0 0 2 2 2 2 Circumsporozoite-related antigen (CRA) NlpE_C PF17185.4 EST42535.1 - 0.074 13.4 3.0 2.6 8.4 0.1 3.7 3 1 0 3 3 3 0 NlpE C-terminal OB domain HSP70 PF00012.20 EST42536.1 - 1.9e-129 432.6 5.6 6e-129 430.9 5.6 1.6 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EST42536.1 - 4e-08 32.5 1.9 4.8e-06 25.6 0.1 3.4 3 1 0 3 3 3 1 MreB/Mbl protein PilM_2 PF11104.8 EST42536.1 - 4.9e-05 22.5 0.1 0.0023 17.0 0.0 2.4 2 0 0 2 2 2 1 Type IV pilus assembly protein PilM; FGGY_C PF02782.16 EST42536.1 - 5e-05 23.1 0.0 8.7e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.11 EST42536.1 - 6.9e-05 22.2 0.0 0.00013 21.3 0.0 1.4 1 0 0 1 1 1 1 StbA protein DDR PF08841.10 EST42536.1 - 0.0049 15.9 0.0 0.019 14.0 0.0 1.9 3 0 0 3 3 3 1 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.6 EST42536.1 - 0.0084 16.5 0.4 0.24 11.8 0.1 2.8 2 2 0 2 2 2 1 Cell division protein FtsA Con-6 PF10346.9 EST42536.1 - 0.056 13.5 0.3 0.74 9.9 0.0 2.5 2 0 0 2 2 2 0 Conidiation protein 6 DnaJ PF00226.31 EST42537.1 - 3.1e-14 52.8 0.3 3.1e-14 52.8 0.3 1.8 2 0 0 2 2 2 1 DnaJ domain Thioredoxin PF00085.20 EST42538.1 - 3.3e-21 75.2 0.0 9.2e-21 73.8 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.6 EST42538.1 - 9.6e-13 48.4 1.6 4.8e-11 42.9 0.4 2.7 2 1 1 3 3 3 1 Thioredoxin-like domain Thioredoxin_2 PF13098.6 EST42538.1 - 0.014 15.9 0.1 0.048 14.1 0.1 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain AhpC-TSA PF00578.21 EST42538.1 - 0.046 13.6 0.2 2.6 8.0 0.0 2.7 2 1 1 3 3 3 0 AhpC/TSA family SRP54 PF00448.22 EST42541.1 - 5.6e-68 228.5 0.2 1.2e-67 227.4 0.2 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 EST42541.1 - 6.6e-26 90.8 2.4 6.6e-26 90.8 2.4 3.9 5 0 0 5 5 5 1 Signal peptide binding domain SRP54_N PF02881.19 EST42541.1 - 1.8e-06 28.1 1.2 3.9e-06 27.0 0.2 2.1 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain CbiA PF01656.23 EST42541.1 - 0.0039 17.2 0.0 0.015 15.4 0.0 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 EST42541.1 - 0.015 15.6 0.1 0.16 12.4 0.0 2.5 2 1 1 3 3 3 0 AAA ATPase domain MeaB PF03308.16 EST42541.1 - 0.019 14.0 0.0 0.41 9.6 0.0 2.6 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Ctf8 PF09696.10 EST42542.1 - 0.05 13.9 0.1 0.072 13.4 0.1 1.3 1 1 0 1 1 1 0 Ctf8 TTRAP PF14203.6 EST42543.1 - 0.022 14.7 2.7 1.7 8.7 0.1 3.3 3 0 0 3 3 3 0 Putative tranposon-transfer assisting protein GnsAB_toxin PF08178.11 EST42543.1 - 0.23 11.4 2.5 3.2 7.8 0.1 3.2 3 0 0 3 3 3 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system PC4 PF02229.16 EST42546.1 - 5.1e-19 67.6 0.7 5.7e-19 67.5 0.7 1.1 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) EF-hand_1 PF00036.32 EST42546.1 - 0.022 14.3 0.4 9.1 6.1 0.1 3.1 3 0 0 3 3 3 0 EF hand DUF4760 PF15956.5 EST42547.1 - 0.021 15.0 0.2 0.049 13.8 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4760) GIT_CC PF16559.5 EST42548.1 - 0.3 11.0 8.4 2.9 7.8 0.2 3.2 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF1633 PF07794.11 EST42549.1 - 0.26 9.4 0.1 0.39 8.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) SHMT PF00464.19 EST42551.1 - 1.6e-78 264.1 0.0 3.4e-77 259.7 0.0 2.0 1 1 0 1 1 1 1 Serine hydroxymethyltransferase MutS_II PF05188.17 EST42551.1 - 0.09 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 MutS domain II zf-C3Hc3H PF13891.6 EST42551.1 - 0.18 12.2 0.5 1.7 9.0 0.8 2.1 2 0 0 2 2 2 0 Potential DNA-binding domain Kelch_4 PF13418.6 EST42552.1 - 4.8e-30 103.3 11.1 3.4e-08 33.4 0.1 6.8 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 EST42552.1 - 4e-23 80.9 4.5 1.2e-09 38.0 0.0 7.4 7 0 0 7 7 7 4 Kelch motif Kelch_3 PF13415.6 EST42552.1 - 3.9e-21 74.8 2.4 0.00083 19.6 0.0 5.9 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 EST42552.1 - 6.8e-21 73.8 15.4 8.2e-07 29.1 0.1 7.8 9 0 0 9 9 9 4 Kelch motif Kelch_1 PF01344.25 EST42552.1 - 1e-16 60.2 4.2 1.9e-09 37.0 0.0 6.1 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 EST42552.1 - 1e-10 41.1 15.6 4.2e-07 29.7 0.0 6.8 8 0 0 8 8 8 2 Kelch motif WD40 PF00400.32 EST42552.1 - 2.4e-05 25.0 11.3 0.12 13.3 0.2 5.2 4 0 0 4 4 4 2 WD domain, G-beta repeat ATP_bind_3 PF01171.20 EST42553.1 - 9.7e-16 58.0 0.0 2.8e-15 56.6 0.0 1.8 1 1 0 1 1 1 1 PP-loop family tRNA_Me_trans PF03054.16 EST42553.1 - 7.1e-05 21.8 0.0 0.0001 21.3 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase PAPS_reduct PF01507.19 EST42553.1 - 0.00016 21.7 0.0 0.00068 19.7 0.0 2.0 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family NAD_synthase PF02540.17 EST42553.1 - 0.054 12.6 0.0 0.089 11.9 0.0 1.4 1 0 0 1 1 1 0 NAD synthase PHF5 PF03660.14 EST42553.1 - 1.4 9.2 6.9 3.3 8.0 1.5 2.5 2 0 0 2 2 2 0 PHF5-like protein zf-MYND PF01753.18 EST42555.1 - 0.042 13.9 0.2 0.042 13.9 0.2 1.9 2 1 0 2 2 2 0 MYND finger DASH_Dad4 PF08650.10 EST42556.1 - 0.031 14.2 2.3 0.038 13.9 0.3 2.1 2 1 0 2 2 2 0 DASH complex subunit Dad4 Ank_2 PF12796.7 EST42557.1 - 1.9e-19 70.0 15.2 0.0014 19.1 0.0 9.8 10 1 1 11 11 11 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EST42557.1 - 1.6e-07 31.5 5.4 0.069 13.5 0.0 8.5 9 0 0 9 9 9 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EST42557.1 - 1.8e-07 31.6 19.6 4.8 7.9 0.0 11.2 12 1 0 12 12 12 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EST42557.1 - 5.2e-07 29.5 15.8 20 6.2 0.0 10.8 12 0 0 12 12 12 2 Ankyrin repeat Ank PF00023.30 EST42557.1 - 1.9e-05 24.9 6.9 25 5.5 0.0 8.6 9 0 0 9 9 9 1 Ankyrin repeat IstB_IS21 PF01695.17 EST42558.1 - 0.067 12.9 0.8 0.2 11.4 0.8 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein EGF_2 PF07974.13 EST42559.1 - 8.3e-06 26.1 45.1 6e-05 23.3 10.4 11.3 10 3 1 11 11 11 6 EGF-like domain Laminin_EGF PF00053.24 EST42559.1 - 7.4e-05 22.8 11.5 7.4e-05 22.8 11.5 9.1 4 2 4 8 8 8 1 Laminin EGF domain Syndecan PF01034.20 EST42559.1 - 0.038 13.9 0.7 0.072 13.0 0.7 1.4 1 0 0 1 1 1 0 Syndecan domain Insulin_TMD PF17870.1 EST42559.1 - 0.056 13.5 0.5 0.11 12.6 0.5 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Actin PF00022.19 EST42560.1 - 4.6e-45 153.9 0.0 7.3e-22 77.5 0.0 2.1 1 1 1 2 2 2 2 Actin BATS PF06968.13 EST42561.1 - 4.8e-22 77.9 0.0 8.7e-22 77.1 0.0 1.5 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 EST42561.1 - 0.016 15.6 0.1 0.039 14.3 0.1 1.8 1 1 0 1 1 1 0 Radical SAM superfamily Metallophos PF00149.28 EST42562.1 - 7.9e-23 82.0 0.0 3.1e-21 76.8 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EST42562.1 - 0.0016 18.6 0.0 0.0024 18.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.25 EST42563.1 - 7.2e-57 192.7 0.8 1.2e-56 192.0 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST42563.1 - 2.7e-32 112.1 0.0 4.5e-32 111.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EST42563.1 - 1.5e-08 34.3 0.6 3.7e-06 26.5 0.1 2.8 2 1 1 3 3 3 2 Kinase-like Kdo PF06293.14 EST42563.1 - 0.0099 15.3 0.5 0.018 14.4 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family USP8_interact PF08941.10 EST42563.1 - 0.78 9.5 5.3 0.23 11.3 2.0 1.7 2 0 0 2 2 2 0 USP8 interacting DUF4094 PF13334.6 EST42563.1 - 0.79 10.2 3.8 2.1 8.8 1.3 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) HJURP_mid PF12346.8 EST42564.1 - 0.029 14.8 3.5 0.073 13.5 3.1 1.8 1 1 1 2 2 2 0 Holliday junction recognition protein-associated repeat Dehydratase_SU PF02287.15 EST42564.1 - 0.049 13.7 1.5 1.3 9.1 0.1 2.3 1 1 1 2 2 2 0 Dehydratase small subunit MFS_1 PF07690.16 EST42565.1 - 1.1e-24 87.1 24.8 1.7e-24 86.4 24.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EST42565.1 - 4.2e-16 58.8 20.9 3.3e-11 42.7 11.6 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 EST42565.1 - 1.8e-10 40.0 27.7 8.4e-07 27.9 15.8 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein Rol_Rep_N PF18106.1 EST42565.1 - 0.018 15.3 0.4 0.071 13.4 0.4 2.1 1 0 0 1 1 1 0 Rolling Circle replication initiation protein N-terminal domain GCD14 PF08704.10 EST42568.1 - 9.3e-33 113.9 0.0 2.1e-32 112.8 0.0 1.6 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 EST42568.1 - 4.7e-06 26.5 0.0 7.7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EST42568.1 - 0.00023 21.8 0.0 0.0012 19.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EST42568.1 - 0.0008 18.9 0.0 0.0017 17.8 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) GCD14_N PF14801.6 EST42568.1 - 0.028 14.3 0.0 0.062 13.2 0.0 1.6 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term TRM PF02005.16 EST42568.1 - 0.1 11.7 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase DUF21 PF01595.20 EST42569.1 - 2.4e-27 95.8 0.9 3.4e-27 95.3 0.9 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 EST42569.1 - 4.6e-10 39.8 1.2 4.9e-06 26.9 0.0 2.3 2 0 0 2 2 2 2 CBS domain Ank_2 PF12796.7 EST42570.1 - 0.0003 21.3 0.5 0.031 14.9 0.2 2.4 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) DUF4441 PF14536.6 EST42570.1 - 0.015 15.5 1.6 0.4 10.9 0.6 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4441) Ank_2 PF12796.7 EST42571.1 - 1.3e-13 51.3 0.7 7.7e-10 39.2 0.7 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EST42571.1 - 1.9e-08 34.4 0.9 0.29 11.5 0.0 4.1 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EST42571.1 - 4.3e-08 33.6 0.7 0.27 11.9 0.2 4.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EST42571.1 - 1.2e-07 31.8 0.1 1.8 9.1 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EST42571.1 - 4.5e-06 26.6 0.6 0.43 11.3 0.1 4.2 4 0 0 4 4 4 2 Ankyrin repeat Proteasome PF00227.26 EST42573.1 - 2.8e-39 134.6 0.4 3.2e-39 134.4 0.4 1.0 1 0 0 1 1 1 1 Proteasome subunit SgrT PF15894.5 EST42573.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Inhibitor of glucose uptake transporter SgrT VSP PF03302.13 EST42574.1 - 0.0008 18.4 31.4 0.0047 15.8 31.4 2.0 1 1 0 1 1 1 1 Giardia variant-specific surface protein DUF4690 PF15756.5 EST42574.1 - 3.7 8.2 4.7 12 6.6 4.7 1.9 1 1 0 1 1 1 0 Small Novel Rich in Cartilage PTH2 PF01981.16 EST42575.1 - 1.3e-06 28.6 0.3 9.3e-06 25.9 0.3 2.0 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 hSH3 PF14603.6 EST42575.1 - 0.015 15.7 0.0 0.025 15.0 0.0 1.3 1 0 0 1 1 1 0 Helically-extended SH3 domain DUF1160 PF06648.11 EST42576.1 - 0.033 14.2 0.2 0.11 12.5 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) Herpes_ori_bp PF02399.15 EST42577.1 - 0.047 11.8 0.2 0.059 11.4 0.2 1.0 1 0 0 1 1 1 0 Origin of replication binding protein KH_1 PF00013.29 EST42578.1 - 1.1e-14 54.0 1.5 2.4e-09 36.9 0.0 3.8 3 1 0 3 3 3 2 KH domain KH_4 PF13083.6 EST42578.1 - 0.0022 17.8 0.0 0.73 9.7 0.0 3.1 3 0 0 3 3 3 2 KH domain KH_2 PF07650.17 EST42578.1 - 0.15 11.9 1.6 9.9 6.1 0.3 2.6 2 0 0 2 2 2 0 KH domain LAGLIDADG_1 PF00961.19 EST42579.1 - 3.6 8.6 10.7 1.9 9.5 1.1 2.2 2 0 0 2 2 2 0 LAGLIDADG endonuclease SRP19 PF01922.17 EST42580.1 - 1.9e-17 64.0 0.0 2.3e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 SRP19 protein LMWPc PF01451.21 EST42583.1 - 1.4e-27 96.8 0.0 1.6e-27 96.6 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Ssu72 PF04722.13 EST42583.1 - 0.033 13.8 0.1 0.17 11.4 0.1 2.0 2 0 0 2 2 2 0 Ssu72-like protein Abhydrolase_5 PF12695.7 EST42586.1 - 9.1e-05 22.3 0.0 0.0004 20.2 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EST42586.1 - 0.0027 17.0 0.0 0.35 10.1 0.0 2.3 1 1 0 2 2 2 2 Serine aminopeptidase, S33 DUF818 PF05677.12 EST42586.1 - 0.028 13.4 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Peptidase_S9 PF00326.21 EST42586.1 - 0.049 13.1 0.0 10 5.5 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family UPF0227 PF05728.12 EST42586.1 - 0.098 12.6 0.0 1.2 9.0 0.0 2.2 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0227) Ank_2 PF12796.7 EST42587.1 - 4.8e-18 65.5 6.7 0.35 11.5 0.0 9.9 8 2 2 10 10 10 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EST42587.1 - 1.6e-06 28.0 9.9 3.9 8.4 0.0 9.7 13 0 0 13 13 13 2 Ankyrin repeat Ank_5 PF13857.6 EST42587.1 - 0.0013 19.0 0.4 70 3.9 0.0 5.6 5 0 0 5 5 5 0 Ankyrin repeats (many copies) Ank PF00023.30 EST42587.1 - 0.0018 18.6 6.1 33 5.2 0.0 7.3 10 0 0 10 10 10 1 Ankyrin repeat Ank_4 PF13637.6 EST42587.1 - 0.086 13.4 11.0 12 6.6 0.0 7.9 9 1 1 10 10 10 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 EST42588.1 - 1.2e-14 54.6 5.8 0.067 13.8 0.0 8.6 7 1 1 8 8 8 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EST42588.1 - 0.00023 21.6 7.7 18 6.1 0.1 7.4 8 0 0 8 8 8 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EST42588.1 - 0.0032 17.8 8.5 16 6.5 0.0 7.7 8 0 0 8 8 8 1 Ankyrin repeat Ank_5 PF13857.6 EST42588.1 - 0.0047 17.2 0.3 9.7 6.7 0.0 4.8 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Ank PF00023.30 EST42588.1 - 0.015 15.7 0.3 2.8 8.5 0.0 4.6 6 0 0 6 6 6 0 Ankyrin repeat Ank_4 PF13637.6 EST42589.1 - 3.2e-05 24.4 0.1 0.0026 18.3 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EST42589.1 - 0.0019 18.7 0.0 0.34 11.5 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) ISP1_C PF18161.1 EST42589.1 - 0.036 14.1 0.3 8.3 6.5 0.1 2.5 2 0 0 2 2 2 0 ISP1 C-terminal TPT PF03151.16 EST42589.1 - 0.041 13.2 0.1 0.068 12.5 0.1 1.3 1 0 0 1 1 1 0 Triose-phosphate Transporter family ISP3_C PF18045.1 EST42589.1 - 0.086 12.7 0.2 13 5.7 0.0 2.6 3 0 0 3 3 3 0 ISP3 C-terminal DUF4477 PF14780.6 EST42590.1 - 0.0065 16.1 0.1 0.014 15.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) WD40 PF00400.32 EST42594.1 - 1.2e-09 38.7 14.3 0.0047 17.7 0.2 7.3 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EST42594.1 - 0.0021 18.3 0.0 0.66 10.3 0.0 4.2 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EST42594.1 - 0.12 12.9 7.8 28 5.4 0.0 6.2 7 0 0 7 7 7 0 PQQ-like domain WD40_like PF17005.5 EST42594.1 - 0.77 9.0 3.4 13 5.0 0.0 3.5 4 0 0 4 4 4 0 WD40-like domain SHIPPO-rpt PF07004.12 EST42595.1 - 2.9e-09 37.4 11.0 0.087 13.8 0.1 4.9 4 0 0 4 4 4 4 Sperm-tail PG-rich repeat Miff PF05644.11 EST42595.1 - 0.076 12.6 0.5 0.1 12.2 0.5 1.1 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff LRR_9 PF14580.6 EST42596.1 - 1.9e-07 30.8 2.5 1.9e-07 30.8 2.5 3.8 4 1 1 5 5 5 1 Leucine-rich repeat LRR_4 PF12799.7 EST42596.1 - 0.00036 20.8 3.6 0.0039 17.6 0.2 5.2 4 2 2 6 6 6 2 Leucine Rich repeats (2 copies) Trans_reg_C PF00486.28 EST42596.1 - 0.0078 16.3 2.1 0.33 11.1 0.2 3.6 3 1 0 3 3 3 1 Transcriptional regulatory protein, C terminal MORN PF02493.20 EST42597.1 - 0.03 14.2 0.4 0.03 14.2 0.4 7.9 10 0 0 10 10 10 0 MORN repeat YabA PF06156.13 EST42599.1 - 0.00043 20.9 1.4 0.00044 20.8 1.4 1.1 1 0 0 1 1 1 1 Initiation control protein YabA ZapB PF06005.12 EST42599.1 - 0.0072 16.7 5.3 0.009 16.4 5.2 1.3 1 1 0 1 1 1 1 Cell division protein ZapB YlqD PF11068.8 EST42599.1 - 0.0097 16.3 1.8 0.011 16.2 1.8 1.1 1 0 0 1 1 1 1 YlqD protein TMF_TATA_bd PF12325.8 EST42599.1 - 0.013 15.7 3.2 0.015 15.5 3.2 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding GrpE PF01025.19 EST42599.1 - 0.025 14.2 2.5 0.028 14.1 2.5 1.0 1 0 0 1 1 1 0 GrpE bZIP_1 PF00170.21 EST42599.1 - 0.035 14.2 3.5 0.045 13.9 3.5 1.3 1 0 0 1 1 1 0 bZIP transcription factor GIT_CC PF16559.5 EST42599.1 - 0.037 13.9 3.1 0.049 13.5 3.1 1.3 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor NRBF2 PF08961.10 EST42599.1 - 0.038 13.6 1.6 0.04 13.5 1.6 1.1 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator TLE_N PF03920.15 EST42599.1 - 0.053 13.6 1.3 0.065 13.3 1.3 1.2 1 0 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain DUF3568 PF12092.8 EST42599.1 - 0.13 12.3 0.2 0.14 12.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) CHD5 PF04420.14 EST42599.1 - 0.14 12.0 1.3 0.16 11.8 1.3 1.0 1 0 0 1 1 1 0 CHD5-like protein DivIC PF04977.15 EST42599.1 - 0.32 10.8 4.6 0.41 10.4 4.6 1.4 1 1 0 1 1 1 0 Septum formation initiator Ank_4 PF13637.6 EST42600.1 - 1.5e-14 54.1 0.2 1.2e-09 38.6 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EST42600.1 - 7.7e-14 52.0 0.1 1.4e-12 48.0 0.1 2.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EST42600.1 - 4e-09 36.0 0.1 0.027 15.0 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EST42600.1 - 2.2e-08 34.2 0.1 0.00026 21.2 0.0 3.5 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EST42600.1 - 2.6e-05 24.5 0.6 0.0041 17.5 0.1 3.2 4 0 0 4 4 4 1 Ankyrin repeat Cas_Cas4 PF01930.17 EST42600.1 - 0.098 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF83 FYVE PF01363.21 EST42602.1 - 1.9e-07 31.1 19.2 8.4e-07 29.0 19.2 2.1 1 1 0 1 1 1 1 FYVE zinc finger Ank_2 PF12796.7 EST42602.1 - 9.4e-06 26.1 0.1 3.6e-05 24.3 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EST42602.1 - 0.00024 21.4 0.0 0.022 15.1 0.0 3.5 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EST42602.1 - 0.00028 21.4 0.2 0.23 12.1 0.0 3.1 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EST42604.1 - 0.029 14.9 0.3 0.16 12.6 0.1 2.3 3 0 0 3 3 3 0 Ankyrin repeats (many copies) AAA_33 PF13671.6 EST42607.1 - 3.6e-08 33.7 0.1 5.7e-07 29.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EST42607.1 - 3.2e-06 27.7 0.9 0.00023 21.7 0.9 2.4 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EST42607.1 - 1.1e-05 25.9 0.0 2.7e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KTI12 PF08433.10 EST42607.1 - 8.6e-05 22.1 12.0 0.014 14.8 9.9 2.9 1 1 1 2 2 2 1 Chromatin associated protein KTI12 AAA_22 PF13401.6 EST42607.1 - 0.00052 20.3 0.2 0.0024 18.2 0.0 2.0 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EST42607.1 - 0.0011 19.0 0.1 0.0025 17.9 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Creatinase_N_2 PF16189.5 EST42607.1 - 0.0039 17.3 1.5 0.0055 16.8 1.5 1.3 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain AAA_21 PF13304.6 EST42607.1 - 0.0081 16.0 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system RNA_helicase PF00910.22 EST42607.1 - 0.011 16.1 0.1 0.037 14.4 0.0 2.0 2 1 0 2 2 2 0 RNA helicase TsaE PF02367.17 EST42607.1 - 0.082 12.9 0.0 0.19 11.8 0.0 1.6 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE dNK PF01712.19 EST42607.1 - 0.17 11.7 7.3 3.1 7.6 7.3 2.2 1 1 0 1 1 1 0 Deoxynucleoside kinase AAA_28 PF13521.6 EST42607.1 - 0.18 12.1 0.1 0.38 11.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EST42607.1 - 0.42 11.1 2.1 1.7 9.1 2.1 2.2 1 1 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 EST42607.1 - 6.8 7.1 10.8 21 5.5 10.8 1.8 1 1 0 1 1 1 0 AAA domain RRM_1 PF00076.22 EST42608.1 - 3.4e-21 74.8 2.1 2.4e-11 43.3 0.0 4.1 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EST42608.1 - 0.00011 22.2 1.0 0.58 10.2 0.0 3.0 3 1 0 3 3 3 2 RNA binding motif Nup35_RRM_2 PF14605.6 EST42608.1 - 0.0013 18.6 0.0 0.2 11.7 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif ACCA PF03255.14 EST42610.1 - 0.044 13.7 0.7 0.044 13.7 0.7 2.3 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Baculo_PEP_C PF04513.12 EST42610.1 - 0.093 12.8 16.5 0.054 13.5 3.3 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MEDS PF14417.6 EST42610.1 - 0.15 11.9 0.1 0.25 11.2 0.1 1.4 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain HrpB7 PF09486.10 EST42610.1 - 0.18 12.2 1.3 1.7 9.0 0.1 2.1 1 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) YtxH PF12732.7 EST42610.1 - 0.56 10.8 4.0 4 8.0 0.1 2.7 2 1 0 2 2 2 0 YtxH-like protein ADIP PF11559.8 EST42610.1 - 0.98 9.5 20.1 1.4 9.0 6.4 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.10 EST42610.1 - 1 9.5 21.5 0.38 10.9 12.6 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FAM76 PF16046.5 EST42610.1 - 2.1 7.6 16.1 11 5.2 15.3 1.9 1 1 1 2 2 2 0 FAM76 protein Spore_III_AB PF09548.10 EST42610.1 - 2.5 8.2 6.7 2.7 8.1 4.7 2.0 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Nnf1 PF03980.14 EST42610.1 - 3.3 8.1 12.6 0.33 11.3 0.4 2.9 3 1 0 3 3 3 0 Nnf1 NYD-SP28 PF14772.6 EST42610.1 - 3.4 7.8 12.6 1.6 8.8 6.1 2.5 1 1 0 2 2 2 0 Sperm tail DivIC PF04977.15 EST42610.1 - 3.9 7.3 20.5 0.18 11.6 4.3 3.5 2 1 2 4 4 4 0 Septum formation initiator DUF948 PF06103.11 EST42610.1 - 5.9 7.2 8.9 0.91 9.8 0.4 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Csm1_N PF18504.1 EST42610.1 - 8.5 6.8 18.2 1.3 9.4 2.1 3.8 2 1 1 3 3 3 0 Csm1 N-terminal domain TolA_bind_tri PF16331.5 EST42610.1 - 8.6 6.5 16.1 7.8 6.7 3.6 3.1 1 1 2 3 3 3 0 TolA binding protein trimerisation Bromo_TP PF07524.13 EST42611.1 - 0.01 15.8 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated IF4E PF01652.18 EST42612.1 - 8.8e-15 54.8 0.5 1.2e-14 54.5 0.5 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E ACT_5 PF13710.6 EST42612.1 - 0.018 14.9 0.1 5.5 6.9 0.0 2.4 2 0 0 2 2 2 0 ACT domain Acyl_transf_1 PF00698.21 EST42613.1 - 0.08 12.4 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Acyl transferase domain THEG PF14912.6 EST42615.1 - 0.011 16.2 0.3 0.022 15.2 0.3 1.6 1 0 0 1 1 1 0 Testicular haploid expressed repeat Tap-RNA_bind PF09162.10 EST42620.1 - 0.07 13.0 5.5 0.078 12.8 2.7 2.6 2 0 0 2 2 2 0 Tap, RNA-binding DHHC PF01529.20 EST42621.1 - 1.7e-15 57.3 11.8 1.7e-15 57.3 11.8 2.2 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF1325 PF07039.11 EST42622.1 - 1.5e-05 25.1 0.0 2.1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain HALZ PF02183.18 EST42624.1 - 0.019 15.2 3.6 0.07 13.4 3.6 2.0 1 0 0 1 1 1 0 Homeobox associated leucine zipper Beta-TrCP_D PF12125.8 EST42624.1 - 0.039 13.9 0.3 0.29 11.1 0.0 2.6 2 0 0 2 2 2 0 D domain of beta-TrCP Herpes_BLRF2 PF05812.12 EST42624.1 - 0.1 12.7 1.3 0.38 10.9 1.3 2.0 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein UPF0449 PF15136.6 EST42624.1 - 3.7 8.1 7.5 38 4.8 4.9 3.0 3 1 0 3 3 3 0 Uncharacterised protein family UPF0449 RRM_1 PF00076.22 EST42625.1 - 1.2e-23 82.7 0.2 6.4e-10 38.7 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EST42625.1 - 7.9e-05 22.7 0.1 0.61 10.2 0.0 2.9 3 1 0 3 3 3 2 RNA recognition motif RFX_DNA_binding PF02257.15 EST42625.1 - 0.12 13.0 0.1 0.25 12.0 0.1 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DUF167 PF02594.16 EST42626.1 - 0.042 14.0 0.3 0.078 13.1 0.3 1.5 1 0 0 1 1 1 0 Uncharacterised ACR, YggU family COG1872 TIP_N PF12457.8 EST42626.1 - 0.21 12.0 1.9 0.29 11.5 0.1 1.9 1 1 1 2 2 2 0 Tuftelin interacting protein N terminal TPR_1 PF00515.28 EST42627.1 - 6.5e-26 89.0 45.8 3.4e-05 23.5 0.0 15.3 15 0 0 15 15 15 8 Tetratricopeptide repeat TPR_2 PF07719.17 EST42627.1 - 4.1e-21 73.3 52.7 0.0011 18.9 0.0 15.7 18 0 0 18 18 16 10 Tetratricopeptide repeat TPR_8 PF13181.6 EST42627.1 - 9.5e-11 41.0 41.2 0.018 15.2 0.0 14.1 17 0 0 17 17 15 4 Tetratricopeptide repeat TPR_11 PF13414.6 EST42627.1 - 8.3e-10 38.2 27.1 0.058 13.1 0.1 10.8 9 3 4 13 13 13 4 TPR repeat TPR_9 PF13371.6 EST42627.1 - 9e-09 35.4 1.9 0.34 11.1 0.0 7.0 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 EST42627.1 - 1.7e-08 34.2 13.8 0.31 11.5 0.0 7.7 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 EST42627.1 - 7.3e-07 29.7 0.3 3 8.6 0.0 7.2 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_12 PF13424.6 EST42627.1 - 4.2e-06 27.0 26.4 0.5 10.7 0.0 9.3 10 1 0 10 10 10 2 Tetratricopeptide repeat PAZ PF02170.22 EST42627.1 - 0.00026 20.8 2.4 0.0021 17.9 1.9 2.7 2 0 0 2 2 2 1 PAZ domain TPR_19 PF14559.6 EST42627.1 - 0.00072 20.0 8.8 0.22 12.0 0.0 6.2 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 EST42627.1 - 0.001 19.7 13.2 18 6.5 0.0 8.0 9 1 1 10 10 8 0 Tetratricopeptide repeat TPR_6 PF13174.6 EST42627.1 - 0.0012 19.3 18.8 9.4 7.1 0.0 8.4 11 0 0 11 11 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 EST42627.1 - 0.042 13.7 0.9 2.1e+02 2.0 0.0 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat MIT PF04212.18 EST42627.1 - 0.057 13.5 12.5 4.8 7.3 0.3 6.4 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.9 EST42627.1 - 0.081 12.4 1.5 43 3.7 0.0 5.1 6 0 0 6 6 6 0 SHNi-TPR TPR_MalT PF17874.1 EST42627.1 - 0.31 10.3 3.5 3.3 7.0 0.0 3.7 4 0 0 4 4 4 0 MalT-like TPR region HTH_Bact PF18768.1 EST42627.1 - 0.65 9.6 11.6 4.3 7.0 0.0 5.3 6 0 0 6 6 6 0 Helix-turn-helix bacterial domain SMC_N PF02463.19 EST42629.1 - 5.2e-68 228.8 0.0 2e-66 223.6 0.0 2.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EST42629.1 - 3e-13 50.2 4.3 2.1e-06 27.7 0.3 2.9 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EST42629.1 - 4.1e-13 50.3 16.3 4.1e-13 50.3 16.3 6.7 2 2 2 4 4 4 1 AAA domain SMC_hinge PF06470.13 EST42629.1 - 1.5e-09 38.2 1.2 5.5e-09 36.4 0.0 2.7 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_29 PF13555.6 EST42629.1 - 2.1e-06 27.4 1.0 6.6e-06 25.8 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain MukB PF04310.12 EST42629.1 - 0.88 9.3 0.0 0.88 9.3 0.0 4.2 5 1 1 6 6 6 0 MukB N-terminal RRM_1 PF00076.22 EST42630.1 - 5e-24 83.9 0.6 3.5e-12 46.0 0.1 3.4 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EST42630.1 - 0.00076 19.5 2.9 0.12 12.5 0.0 3.7 5 0 0 5 5 5 2 RNA recognition motif Smg4_UPF3 PF03467.15 EST42630.1 - 0.021 14.8 0.1 0.021 14.8 0.1 3.2 4 1 1 5 5 5 0 Smg-4/UPF3 family Ribosomal_L10 PF00466.20 EST42632.1 - 0.065 13.4 0.6 0.15 12.2 0.6 1.5 1 0 0 1 1 1 0 Ribosomal protein L10 L27 PF02828.16 EST42632.1 - 0.22 11.3 1.7 0.32 10.8 0.3 1.9 2 0 0 2 2 2 0 L27 domain zf-C2HC5 PF06221.13 EST42637.1 - 2.9e-11 43.2 6.3 3.9e-11 42.8 6.3 1.2 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Lactamase_B_6 PF16661.5 EST42638.1 - 2.5e-06 27.1 0.0 9.2e-06 25.2 0.0 2.0 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain DUF3979 PF13141.6 EST42638.1 - 0.089 13.1 5.0 0.53 10.6 0.3 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3979) BLACT_WH PF17778.1 EST42640.1 - 0.16 12.0 0.0 0.32 11.0 0.0 1.5 1 1 1 2 2 2 0 Beta-lactamase associated winged helix domain Phosphodiest PF01663.22 EST42641.1 - 0.01 15.5 1.0 1.9 8.0 0.1 2.2 1 1 1 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase RRM_DME PF15628.6 EST42642.1 - 0.058 13.6 0.1 0.25 11.6 0.0 2.0 1 1 1 2 2 2 0 RRM in Demeter DUF5409 PF17421.2 EST42642.1 - 0.26 12.0 6.1 0.57 10.9 5.4 2.0 2 1 0 2 2 2 0 Family of unknown function (DUF5409) Sugar_tr PF00083.24 EST42643.1 - 1.2e-18 67.2 9.1 1.5e-18 67.0 9.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EST42643.1 - 0.0005 19.1 5.1 0.00056 18.9 5.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily VSP PF03302.13 EST42645.1 - 0.00013 21.0 30.0 0.00019 20.4 30.0 1.4 1 1 0 1 1 1 1 Giardia variant-specific surface protein DUF4366 PF14283.6 EST42645.1 - 0.2 11.7 1.8 0.3 11.1 1.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) VSP PF03302.13 EST42648.1 - 3.1e-11 42.8 249.6 0.00014 20.9 35.0 9.3 1 1 9 10 10 10 7 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST42648.1 - 0.0059 16.8 20.5 0.0059 16.8 20.5 10.7 1 1 10 11 11 11 1 Furin-like repeat, cysteine-rich VSP PF03302.13 EST42650.1 - 0.00029 19.8 37.5 0.00029 19.8 37.5 2.7 1 1 1 2 2 2 2 Giardia variant-specific surface protein DUF3624 PF12292.8 EST42650.1 - 0.00095 19.5 0.2 0.00095 19.5 0.2 3.8 3 1 1 4 4 4 1 Protein of unknown function (DUF3624) DUF4313 PF14190.6 EST42650.1 - 0.012 15.5 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4313) zf-CCHH PF10283.9 EST42651.1 - 0.55 10.3 2.9 6.1 6.9 0.2 3.1 3 0 0 3 3 3 0 PBZ domain RRP36 PF06102.12 EST42654.1 - 0.068 13.1 0.3 0.12 12.3 0.3 1.3 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 LRR_6 PF13516.6 EST42655.1 - 0.00049 19.9 1.3 23 5.4 0.0 5.1 4 1 0 5 5 5 2 Leucine Rich repeat LRR_8 PF13855.6 EST42655.1 - 0.045 13.5 3.2 27 4.6 1.3 3.5 2 2 0 2 2 2 0 Leucine rich repeat LRR_1 PF00560.33 EST42655.1 - 0.42 11.3 3.0 2.6e+02 2.8 1.5 4.6 3 2 0 3 3 3 0 Leucine Rich Repeat Insulin_TMD PF17870.1 EST42656.1 - 0.0063 16.6 0.2 0.018 15.1 0.2 1.8 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment CytochromB561_N PF09786.9 EST42656.1 - 0.0076 15.3 0.0 0.0088 15.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome B561, N terminal DUF3094 PF11293.8 EST42656.1 - 0.15 11.8 0.2 0.4 10.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) HP0268 PF18618.1 EST42657.1 - 0.71 10.3 5.4 2.1 8.8 0.8 2.8 2 0 0 2 2 2 0 HP0268 E1-E2_ATPase PF00122.20 EST42658.1 - 7.1e-20 71.3 1.1 3e-16 59.5 1.4 2.9 2 0 0 2 2 2 2 E1-E2 ATPase Hydrolase PF00702.26 EST42658.1 - 1.3e-15 58.3 0.0 3.5e-07 30.7 0.0 2.4 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EST42658.1 - 4.2e-05 23.5 0.1 0.00014 21.8 0.1 1.9 1 0 0 1 1 1 1 Cation transport ATPase (P-type) LMF1 PF06762.14 EST42658.1 - 0.034 13.3 2.5 0.1 11.7 2.5 1.8 1 0 0 1 1 1 0 Lipase maturation factor SRP54_N PF02881.19 EST42658.1 - 0.036 14.3 0.0 0.14 12.4 0.0 2.1 1 0 0 1 1 1 0 SRP54-type protein, helical bundle domain Hydrolase_3 PF08282.12 EST42658.1 - 6.6 6.4 17.4 0.18 11.5 0.3 3.8 3 1 1 4 4 4 0 haloacid dehalogenase-like hydrolase Peptidase_M29 PF02073.15 EST42659.1 - 7.9e-117 390.5 0.2 8.8e-117 390.3 0.2 1.0 1 0 0 1 1 1 1 Thermophilic metalloprotease (M29) EF-hand_7 PF13499.6 EST42660.1 - 1.6e-05 25.3 2.0 0.0021 18.5 1.9 2.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EST42660.1 - 0.00024 20.8 0.3 0.43 10.7 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 EST42660.1 - 0.0029 17.0 0.0 1.9 8.2 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_10 PF14788.6 EST42660.1 - 0.035 14.0 0.3 0.23 11.4 0.1 2.4 2 0 0 2 2 2 0 EF hand EF-hand_4 PF12763.7 EST42660.1 - 0.095 12.7 3.1 0.92 9.5 0.4 2.6 1 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand DUF915 PF06028.11 EST42660.1 - 0.1 11.9 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) WD40 PF00400.32 EST42661.1 - 4.3e-31 106.5 14.1 1.2e-05 26.0 0.1 7.7 7 0 0 7 7 7 5 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 EST42661.1 - 3.8e-08 32.8 0.4 3.7e-05 23.0 0.0 2.7 1 1 1 2 2 2 2 Coatomer WD associated region ANAPC4_WD40 PF12894.7 EST42661.1 - 6.7e-08 32.7 0.1 0.73 10.2 0.0 5.1 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain COPI_C PF06957.11 EST42661.1 - 2.2 6.9 16.2 0.038 12.8 8.1 2.1 1 1 1 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus Sec34 PF04136.15 EST42662.1 - 0.003 17.4 5.0 0.0037 17.2 5.0 1.2 1 0 0 1 1 1 1 Sec34-like family DUF2315 PF10231.9 EST42662.1 - 0.045 13.8 0.3 0.076 13.1 0.3 1.4 1 0 0 1 1 1 0 Apoptogenic protein 1 Prenyltransf PF01255.19 EST42665.1 - 9.1e-10 38.4 0.2 6.8e-06 25.8 0.0 2.2 1 1 1 2 2 2 2 Putative undecaprenyl diphosphate synthase Peptidase_M50 PF02163.22 EST42666.1 - 4.2e-09 36.0 7.6 1.1e-06 28.1 7.5 2.8 1 1 0 1 1 1 1 Peptidase family M50 Peptidase_M50B PF13398.6 EST42666.1 - 0.02 14.5 0.2 0.02 14.5 0.2 2.8 3 0 0 3 3 3 0 Peptidase M50B-like FA_desaturase PF00487.24 EST42666.1 - 0.68 9.7 1.9 0.85 9.4 0.4 1.9 2 0 0 2 2 2 0 Fatty acid desaturase DUF3449 PF11931.8 EST42668.1 - 6.1e-05 22.9 0.2 9.8e-05 22.2 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) RIBIOP_C PF04950.12 EST42671.1 - 4.4e-38 131.4 1.6 4.4e-38 131.4 1.6 1.8 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal RabGAP-TBC PF00566.18 EST42672.1 - 6e-35 120.9 1.3 7.8e-35 120.5 1.3 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain FAST_2 PF08368.12 EST42674.1 - 0.72 10.7 12.2 1.6 9.5 0.5 4.5 2 1 2 4 4 4 0 FAST kinase-like protein, subdomain 2 V-ATPase_G PF03179.15 EST42675.1 - 7.9e-17 61.7 15.2 8.7e-17 61.6 15.2 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit V-ATPase_G_2 PF16999.5 EST42675.1 - 3.6e-05 24.1 16.3 4.2e-05 23.9 16.3 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit SCAB_CC PF16712.5 EST42675.1 - 0.0031 17.4 9.4 0.0031 17.4 9.4 1.7 1 1 1 2 2 2 1 Coiled-coil regions of plant-specific actin-binding protein Phasin PF05597.11 EST42675.1 - 0.0065 16.5 6.9 0.0076 16.2 6.9 1.1 1 0 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) DivIVA PF05103.13 EST42675.1 - 0.013 15.6 8.5 0.013 15.6 8.5 2.0 1 1 1 2 2 2 0 DivIVA protein ATP-synt_B PF00430.18 EST42675.1 - 0.02 15.0 19.5 0.022 14.9 17.6 1.7 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) DUF4208 PF13907.6 EST42675.1 - 0.046 14.2 1.5 0.072 13.5 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) NVEALA PF14055.6 EST42675.1 - 0.049 13.6 1.4 0.072 13.1 1.4 1.3 1 0 0 1 1 1 0 NVEALA protein DUF3552 PF12072.8 EST42675.1 - 0.13 11.7 17.0 0.25 10.7 10.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) HrpE PF06188.12 EST42675.1 - 0.14 12.0 7.8 0.16 11.8 7.8 1.2 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E DOG1 PF14144.6 EST42675.1 - 0.19 12.0 2.6 0.61 10.4 0.5 2.0 2 0 0 2 2 2 0 Seed dormancy control Prominin PF05478.11 EST42675.1 - 0.2 9.6 4.3 0.21 9.5 4.3 1.0 1 0 0 1 1 1 0 Prominin OmpH PF03938.14 EST42675.1 - 0.38 11.1 15.2 0.45 10.8 15.2 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) RNase_J_C PF17770.1 EST42675.1 - 0.55 11.3 6.4 1 10.5 3.1 2.4 1 1 1 2 2 2 0 Ribonuclease J C-terminal domain DUF883 PF05957.13 EST42675.1 - 0.74 10.5 9.8 10 6.8 9.0 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 EST42675.1 - 0.75 10.4 9.5 6.5 7.4 9.5 2.1 1 1 0 1 1 1 0 YtxH-like protein Mitofilin PF09731.9 EST42675.1 - 0.92 8.3 17.4 1 8.1 17.4 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF2294 PF10057.9 EST42675.1 - 1.1 9.4 6.3 1 9.5 1.6 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2294) Porin_5 PF16930.5 EST42675.1 - 7.7 4.9 10.2 17 3.7 10.2 1.7 1 1 0 1 1 1 0 Putative porin Pec_lyase_N PF04431.13 EST42676.1 - 0.12 12.6 0.0 1.5 9.1 0.0 2.5 2 0 0 2 2 2 0 Pectate lyase, N terminus Myb_DNA-bind_6 PF13921.6 EST42678.1 - 2.1e-08 34.3 7.4 0.00025 21.2 1.5 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EST42678.1 - 6.5e-08 32.6 6.0 9.2e-05 22.6 1.6 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST42678.1 - 0.00053 19.8 3.5 0.00053 19.8 3.5 2.7 1 1 1 2 2 2 1 Myb DNA-binding like Tox-GHH PF15636.6 EST42678.1 - 0.019 15.0 0.8 7 6.7 0.1 2.5 2 0 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin SANT_DAMP1_like PF16282.5 EST42678.1 - 0.22 11.7 4.4 2.6 8.3 0.8 2.4 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 DUF573 PF04504.14 EST42678.1 - 3.3 8.4 8.9 5.5 7.7 4.8 2.7 1 1 2 3 3 3 0 Protein of unknown function, DUF573 DUF3149 PF11346.8 EST42679.1 - 0.0034 17.0 0.5 0.0058 16.2 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3149) Torsin PF06309.11 EST42680.1 - 0.044 13.9 0.0 0.064 13.4 0.0 1.4 1 0 0 1 1 1 0 Torsin LRR_6 PF13516.6 EST42682.1 - 1e-27 93.8 31.4 0.00068 19.5 0.1 11.3 11 0 0 11 11 11 9 Leucine Rich repeat LRR_4 PF12799.7 EST42682.1 - 1.7e-05 25.1 33.5 0.032 14.7 1.4 8.2 5 1 4 9 9 9 5 Leucine Rich repeats (2 copies) Lactamase_B_2 PF12706.7 EST42683.1 - 1.6e-10 40.9 0.0 2e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EST42683.1 - 2.6e-06 27.6 0.0 4.8e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Peptidase_S41 PF03572.18 EST42684.1 - 0.0088 15.6 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S41 LRR_8 PF13855.6 EST42685.1 - 1.4e-11 43.9 25.7 3.5e-06 26.7 0.5 6.7 5 3 3 8 8 8 5 Leucine rich repeat LRR_4 PF12799.7 EST42685.1 - 1.2e-10 41.4 40.9 0.0012 19.2 0.3 9.9 8 3 2 11 11 11 6 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EST42685.1 - 0.0077 16.2 19.9 0.14 12.3 0.0 9.1 10 0 0 10 10 10 1 Leucine Rich repeat LRR_9 PF14580.6 EST42685.1 - 0.26 10.8 0.1 0.26 10.8 0.1 5.1 3 1 2 6 6 6 0 Leucine-rich repeat Band_7 PF01145.25 EST42686.1 - 6.5e-15 55.6 0.7 6.5e-15 55.6 0.7 1.8 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 EST42686.1 - 0.023 14.4 0.8 0.057 13.1 0.1 1.8 2 0 0 2 2 2 0 SPFH domain-Band 7 family Lipase_3 PF01764.25 EST42687.1 - 1.2e-11 44.7 0.0 2.2e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Pro_isomerase PF00160.21 EST42688.1 - 6.3e-48 163.0 0.1 7.2e-48 162.8 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pih1_fungal_CS PF18482.1 EST42689.1 - 0.1 13.1 1.6 1.3 9.6 1.6 2.1 1 1 0 1 1 1 0 Fungal Pih1 CS domain IF2_N PF04760.15 EST42690.1 - 0.26 11.2 2.2 0.42 10.5 0.9 2.1 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region Dala_Dala_lig_C PF07478.13 EST42691.1 - 0.017 14.7 0.1 0.032 13.8 0.1 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus SelB-wing_2 PF09106.11 EST42691.1 - 0.049 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Elongation factor SelB, winged helix AAA PF00004.29 EST42692.1 - 4.1e-37 127.6 0.0 8.7e-37 126.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EST42692.1 - 9.8e-11 41.3 0.2 2.4e-10 40.0 0.2 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EST42692.1 - 5e-05 23.8 0.1 0.0035 17.7 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 EST42692.1 - 6.2e-05 23.2 0.0 0.00012 22.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EST42692.1 - 7.6e-05 23.0 1.5 0.006 16.9 0.0 2.7 2 1 1 3 3 2 1 AAA domain AAA_7 PF12775.7 EST42692.1 - 0.00013 21.6 0.0 0.00022 20.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 EST42692.1 - 0.00016 21.6 0.0 0.00067 19.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 EST42692.1 - 0.00018 20.8 0.0 0.00032 19.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ATPase PF06745.13 EST42692.1 - 0.00025 20.5 1.4 0.0026 17.1 0.0 2.6 2 1 1 3 3 3 1 KaiC TniB PF05621.11 EST42692.1 - 0.0016 17.9 0.0 0.13 11.6 0.0 2.4 1 1 0 2 2 2 1 Bacterial TniB protein AAA_18 PF13238.6 EST42692.1 - 0.0019 18.8 0.0 0.005 17.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain Prot_ATP_ID_OB PF16450.5 EST42692.1 - 0.0026 17.7 0.0 0.0064 16.4 0.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain Mg_chelatase PF01078.21 EST42692.1 - 0.0028 17.1 0.0 0.0068 15.8 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 EST42692.1 - 0.0034 16.7 0.0 0.0062 15.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 EST42692.1 - 0.0059 16.6 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EST42692.1 - 0.0076 16.8 0.1 0.033 14.7 0.0 2.0 1 1 1 2 2 1 1 ABC transporter RuvB_N PF05496.12 EST42692.1 - 0.0085 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EST42692.1 - 0.015 15.7 0.0 0.031 14.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 EST42692.1 - 0.017 15.0 0.3 0.076 12.9 0.0 2.3 2 1 1 3 3 2 0 NTPase T2SSE PF00437.20 EST42692.1 - 0.027 13.5 0.0 0.052 12.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 EST42692.1 - 0.03 14.1 0.0 0.066 12.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_29 PF13555.6 EST42692.1 - 0.04 13.7 0.0 0.081 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_11 PF13086.6 EST42692.1 - 0.052 13.3 0.2 0.36 10.6 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EST42692.1 - 0.052 14.0 0.4 0.36 11.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EST42692.1 - 0.057 13.3 0.0 2 8.3 0.0 2.4 1 1 1 2 2 2 0 NACHT domain PPV_E1_C PF00519.17 EST42692.1 - 0.061 12.2 0.1 0.095 11.5 0.1 1.2 1 0 0 1 1 1 0 Papillomavirus helicase AAA_19 PF13245.6 EST42692.1 - 0.065 13.6 0.0 0.22 11.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EST42692.1 - 0.072 12.7 0.0 0.2 11.2 0.0 1.7 2 0 0 2 2 1 0 AAA domain Sigma54_activ_2 PF14532.6 EST42692.1 - 0.081 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain TsaE PF02367.17 EST42692.1 - 0.085 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMR_HSR1 PF01926.23 EST42692.1 - 0.14 12.3 0.0 3.3 7.8 0.0 2.9 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.6 EST42692.1 - 0.15 11.8 0.0 0.55 9.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain DAP3 PF10236.9 EST42692.1 - 0.19 10.9 0.6 2.5 7.2 0.0 2.6 2 1 1 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 AAA_23 PF13476.6 EST42692.1 - 5.1 7.6 5.5 1.8 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF348 PF03990.14 EST42693.1 - 0.31 10.8 1.0 0.81 9.5 0.0 2.2 2 0 0 2 2 2 0 G5-linked-Ubiquitin-like domain Kinesin PF00225.23 EST42694.1 - 6.5e-81 271.8 1.8 6.5e-81 271.8 1.8 2.8 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EST42694.1 - 2e-31 108.9 0.2 2e-31 108.9 0.2 4.7 3 2 2 5 5 5 1 Microtubule binding Flt3_lig PF02947.14 EST42695.1 - 0.013 15.6 0.7 0.023 14.9 0.7 1.5 1 0 0 1 1 1 0 flt3 ligand Hexapep PF00132.24 EST42696.1 - 1.1e-10 40.8 11.8 3.2e-06 26.6 6.4 2.8 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EST42696.1 - 0.00011 21.8 16.7 0.0012 18.5 8.4 3.1 2 2 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase UFD1 PF03152.14 EST42697.1 - 3.5e-31 108.0 0.0 5.7e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 DHC_N2 PF08393.13 EST42698.1 - 2.5e-124 415.4 8.4 2.5e-124 415.4 8.4 4.3 4 1 1 5 5 5 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 EST42698.1 - 2.2e-104 350.1 13.2 2.2e-104 350.1 13.2 3.4 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 EST42698.1 - 2e-57 194.7 0.3 2e-57 194.7 0.3 1.9 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DUF3211 PF11485.8 EST42698.1 - 0.0017 18.6 0.1 0.0092 16.2 0.1 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3211) DUF948 PF06103.11 EST42698.1 - 0.053 13.8 9.8 2.9 8.2 0.1 5.4 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF948) AAA PF00004.29 EST42698.1 - 0.082 13.3 0.0 0.36 11.3 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Flavodoxin_1 PF00258.25 EST42699.1 - 2.5e-06 27.7 0.0 4.6e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin Lactamase_B PF00753.27 EST42699.1 - 0.0039 17.2 0.0 0.0071 16.4 0.0 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EST42699.1 - 0.013 15.0 0.0 0.024 14.2 0.0 1.5 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 EST42700.1 - 0.0019 17.8 0.1 0.0038 16.8 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain FMN_red PF03358.15 EST42700.1 - 0.014 15.2 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 NADPH-dependent FMN reductase Lactamase_B PF00753.27 EST42700.1 - 0.014 15.4 0.1 0.036 14.1 0.1 1.7 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Flavodoxin_1 PF00258.25 EST42700.1 - 0.021 15.0 0.0 0.052 13.8 0.0 1.7 1 0 0 1 1 1 0 Flavodoxin DUF2108 PF09881.9 EST42700.1 - 0.45 10.5 4.3 0.97 9.4 0.3 2.6 3 0 0 3 3 3 0 Predicted membrane protein (DUF2108) Plasmid_parti PF01672.16 EST42701.1 - 0.32 11.6 8.0 0.32 11.7 1.7 2.6 1 1 1 2 2 2 0 Putative plasmid partition protein Ank_3 PF13606.6 EST42702.1 - 2.2e-07 30.6 0.2 0.0028 18.0 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EST42702.1 - 3.5e-07 30.7 0.0 3.6e-06 27.5 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EST42702.1 - 5.2e-05 23.7 0.1 0.21 12.2 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EST42702.1 - 0.0035 17.7 0.0 0.29 11.6 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 EST42702.1 - 0.0036 17.6 0.0 0.36 11.2 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) kleA_kleC PF17383.2 EST42703.1 - 2 8.8 15.5 1.4 9.3 0.2 6.0 4 1 1 5 5 5 0 Uncharacterized KorC regulated protein A DUF3772 PF12607.8 EST42704.1 - 0.23 11.3 3.7 2.2 8.1 0.7 3.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) AAA_6 PF12774.7 EST42705.1 - 9.2e-110 366.7 0.0 9.2e-110 366.7 0.0 2.6 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EST42705.1 - 7.1e-82 275.6 19.6 7.1e-82 275.6 19.6 6.9 4 1 3 8 8 8 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 EST42705.1 - 4.7e-50 170.8 48.2 4.7e-50 170.8 48.2 4.6 2 1 2 5 5 5 1 Dynein heavy chain, N-terminal region 1 AAA_5 PF07728.14 EST42705.1 - 0.011 15.7 1.1 0.2 11.7 0.0 3.3 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) Inhibitor_G39P PF11417.8 EST42705.1 - 0.46 11.0 3.8 8.1 7.1 0.4 3.4 3 0 0 3 3 3 0 Loader and inhibitor of phage G40P AAA_18 PF13238.6 EST42705.1 - 0.49 10.9 3.5 1.3 9.5 0.0 3.8 4 0 0 4 4 4 0 AAA domain XPG_I PF00867.18 EST42706.1 - 4.9e-12 46.0 0.1 1.9e-11 44.1 0.1 2.1 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EST42706.1 - 8.5e-09 35.8 0.0 2.3e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 EST42706.1 - 0.0002 20.9 0.0 0.00039 20.0 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing dNK PF01712.19 EST42707.1 - 5.9e-51 173.2 1.7 7.3e-51 172.9 1.7 1.0 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.6 EST42707.1 - 1.9e-11 44.6 0.1 4.7e-11 43.4 0.0 1.6 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 EST42707.1 - 1.3e-08 35.1 0.0 2.4e-08 34.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 EST42707.1 - 4.6e-06 26.8 0.2 0.019 15.1 0.0 2.4 2 1 0 2 2 2 2 Shikimate kinase Thymidylate_kin PF02223.17 EST42707.1 - 9.3e-06 25.4 2.3 0.00011 21.9 0.6 2.7 1 1 1 2 2 2 1 Thymidylate kinase AAA_17 PF13207.6 EST42707.1 - 0.00019 21.9 0.7 0.5 10.8 0.0 2.6 3 0 0 3 3 3 2 AAA domain PPK2 PF03976.14 EST42707.1 - 0.0015 18.1 0.4 0.0038 16.8 0.4 1.7 1 1 0 1 1 1 1 Polyphosphate kinase 2 (PPK2) RNA_helicase PF00910.22 EST42707.1 - 0.01 16.2 0.6 1.6 9.2 0.0 2.5 2 1 0 2 2 2 0 RNA helicase AAA_22 PF13401.6 EST42707.1 - 0.016 15.4 0.0 0.16 12.3 0.0 2.3 2 1 1 3 3 3 0 AAA domain AAA_28 PF13521.6 EST42707.1 - 0.017 15.4 0.0 0.024 14.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.10 EST42707.1 - 0.039 13.4 1.5 1.2 8.5 1.5 2.1 1 1 0 1 1 1 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 EST42707.1 - 0.063 12.5 0.1 8.6 5.6 0.0 2.5 3 0 0 3 3 3 0 Zeta toxin APS_kinase PF01583.20 EST42707.1 - 0.068 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase IstB_IS21 PF01695.17 EST42707.1 - 0.082 12.6 0.0 0.23 11.2 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein Herpes_TK PF00693.18 EST42707.1 - 0.098 11.9 0.0 0.25 10.6 0.0 1.7 1 1 1 2 2 2 0 Thymidine kinase from herpesvirus AAA_14 PF13173.6 EST42707.1 - 0.099 12.7 1.6 8.1 6.5 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EST42707.1 - 0.16 11.7 0.0 0.65 9.8 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain Cytidylate_kin PF02224.18 EST42707.1 - 0.17 11.6 0.0 5.2 6.7 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase NB-ARC PF00931.22 EST42707.1 - 0.24 10.5 1.2 0.28 10.3 0.1 1.9 2 1 0 2 2 2 0 NB-ARC domain Acetyltransf_1 PF00583.25 EST42708.1 - 2.1e-07 31.1 0.0 3.4e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EST42708.1 - 6.2e-06 26.2 0.0 1.2e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EST42708.1 - 0.0017 18.7 0.0 0.0043 17.5 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Bromodomain PF00439.25 EST42708.1 - 0.017 15.1 0.1 0.049 13.7 0.1 1.8 1 0 0 1 1 1 0 Bromodomain Hydrolase_4 PF12146.8 EST42709.1 - 7.5e-07 28.7 0.0 1.6e-06 27.5 0.0 1.5 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EST42709.1 - 1.5e-05 25.7 0.0 1.6e-05 25.6 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EST42709.1 - 0.0015 18.2 0.0 0.053 13.2 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 EST42709.1 - 0.072 12.0 0.0 0.23 10.4 0.0 1.7 2 0 0 2 2 2 0 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 EST42710.1 - 8.9e-05 23.2 0.0 0.00011 22.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EST42710.1 - 0.00074 18.9 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EST42710.1 - 0.0035 17.0 0.0 0.015 15.0 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF2974 PF11187.8 EST42710.1 - 0.017 14.7 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 EST42710.1 - 0.051 13.4 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Ion_trans_2 PF07885.16 EST42711.1 - 3.4e-07 30.1 5.8 3.4e-07 30.1 5.8 3.0 1 1 1 2 2 2 1 Ion channel DUF4525 PF15027.6 EST42711.1 - 2.8 7.7 6.1 2.5 7.8 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4525) EVC2_like PF12297.8 EST42711.1 - 9.7 4.7 8.5 7.7 5.1 3.4 2.0 1 1 0 2 2 2 0 Ellis van Creveld protein 2 like protein TPR_1 PF00515.28 EST42712.1 - 0.0006 19.5 0.0 0.0018 18.0 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 EST42712.1 - 0.00073 19.5 0.0 0.0096 16.0 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EST42712.1 - 0.046 14.4 0.0 0.23 12.1 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EST42712.1 - 0.047 13.7 0.0 0.21 11.7 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1040 PF06288.13 EST42712.1 - 0.079 13.4 4.5 0.056 13.8 0.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1040) TPR_12 PF13424.6 EST42712.1 - 0.24 11.7 2.5 1.9 8.8 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat ParE-like_toxin PF15781.5 EST42714.1 - 0.0096 15.9 0.7 0.054 13.5 0.3 2.7 2 0 0 2 2 2 1 ParE-like toxin of type II bacterial toxin-antitoxin system Thioredoxin_8 PF13905.6 EST42714.1 - 3.6 8.0 10.4 7.8 6.9 0.8 4.3 3 0 0 3 3 3 0 Thioredoxin-like Acetyltransf_10 PF13673.7 EST42716.1 - 8.4e-07 29.0 0.1 1e-06 28.7 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EST42716.1 - 6.1e-06 26.5 0.0 7.8e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family ToxB_N PF18224.1 EST42716.1 - 0.14 12.1 0.4 0.38 10.7 0.0 2.0 2 1 1 3 3 3 0 ToxB N-terminal domain DNA_pol3_delta2 PF13177.6 EST42717.1 - 3e-13 49.9 0.0 1.1e-12 48.1 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 EST42717.1 - 1.7e-05 25.3 0.0 3.4e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EST42717.1 - 0.014 15.4 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EST42717.1 - 0.017 15.4 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EST42717.1 - 0.023 15.1 0.5 1.8 8.9 0.1 2.7 2 1 0 2 2 2 0 AAA ATPase domain TBCC PF07986.12 EST42717.1 - 0.099 12.4 0.4 0.35 10.6 0.2 2.0 2 0 0 2 2 2 0 Tubulin binding cofactor C LRRFIP PF09738.9 EST42718.1 - 0.078 12.4 12.2 0.17 11.4 12.2 1.6 1 1 0 1 1 1 0 LRRFIP family SNF2_N PF00176.23 EST42719.1 - 3.6e-57 193.7 5.1 8.6e-57 192.4 5.1 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EST42719.1 - 5.1e-18 65.4 1.9 2e-17 63.5 0.0 3.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF86 PF01934.17 EST42719.1 - 0.041 13.8 1.2 0.13 12.1 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF86 MMR_HSR1_C PF08438.10 EST42719.1 - 0.12 13.0 1.7 0.58 10.7 0.5 2.9 2 0 0 2 2 2 0 GTPase of unknown function C-terminal DHC_N2 PF08393.13 EST42720.1 - 5.1e-126 421.0 7.3 5.1e-126 421.0 7.3 4.5 4 1 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 EST42720.1 - 1.7e-112 377.0 8.2 1.7e-112 377.0 8.2 2.7 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 EST42720.1 - 4.4e-64 216.5 0.6 4.4e-64 216.5 0.6 2.3 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region zf-ZPR1 PF03367.13 EST42720.1 - 0.00025 20.9 0.0 0.0027 17.6 0.0 2.8 2 0 0 2 2 2 1 ZPR1 zinc-finger domain AAA PF00004.29 EST42720.1 - 0.034 14.6 0.2 0.31 11.5 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UPF0220 PF05255.11 EST42720.1 - 0.13 11.8 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0220) DUF3211 PF11485.8 EST42720.1 - 0.14 12.3 4.0 0.099 12.9 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3211) TRPM_tetra PF16519.5 EST42720.1 - 0.83 9.8 4.7 0.32 11.1 0.5 2.7 2 0 0 2 2 2 0 Tetramerisation domain of TRPM Dynein_AAA_lid PF17852.1 EST42721.1 - 1e-16 61.2 0.3 4e-15 56.0 0.3 2.2 1 1 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_7 PF12775.7 EST42721.1 - 1.2e-05 24.9 0.0 9.3e-05 22.0 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region Furin-like_2 PF15913.5 EST42722.1 - 0.0047 17.1 2.9 0.0047 17.1 2.9 2.1 1 1 1 2 2 2 1 Furin-like repeat, cysteine-rich VSP PF03302.13 EST42724.1 - 2.7e-09 36.4 37.2 2.7e-09 36.4 37.2 3.4 1 1 2 3 3 3 2 Giardia variant-specific surface protein Neogenin_C PF06583.12 EST42724.1 - 0.052 13.4 4.7 0.085 12.7 4.7 1.3 1 0 0 1 1 1 0 Neogenin C-terminus Furin-like_2 PF15913.5 EST42724.1 - 3.4 7.9 70.4 0.14 12.3 20.3 4.4 1 1 2 4 4 4 0 Furin-like repeat, cysteine-rich VSP PF03302.13 EST42725.1 - 7.9e-09 34.9 75.5 3e-08 32.9 36.1 5.7 1 1 4 5 5 5 4 Giardia variant-specific surface protein DUF4366 PF14283.6 EST42726.1 - 0.6 10.2 0.0 0.6 10.2 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4366) CreD PF06123.12 EST42728.1 - 0.69 8.6 7.4 1.1 8.0 7.4 1.2 1 0 0 1 1 1 0 Inner membrane protein CreD MFS_1 PF07690.16 EST42729.1 - 0.088 11.7 0.9 0.1 11.5 0.9 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily Histone PF00125.24 EST42732.1 - 3.6e-31 108.2 4.8 4.3e-31 108.0 4.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EST42732.1 - 3.3e-06 27.2 1.0 5.9e-06 26.4 0.1 1.8 1 1 1 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EST42732.1 - 0.0011 19.3 0.8 0.0018 18.6 0.2 1.6 2 0 0 2 2 2 1 CENP-S protein Nepo_coat_C PF03688.14 EST42732.1 - 0.0086 15.9 0.0 0.01 15.7 0.0 1.1 1 0 0 1 1 1 1 Nepovirus coat protein, C-terminal domain TFIID-31kDa PF02291.15 EST42732.1 - 0.0094 16.0 0.1 0.016 15.3 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit DUF3509 PF12021.8 EST42732.1 - 0.83 9.5 5.0 0.28 10.9 0.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3509) ABC_tran PF00005.27 EST42733.1 - 5.6e-12 46.3 0.0 2.1e-11 44.5 0.0 2.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EST42733.1 - 0.0001 22.2 0.0 0.087 12.6 0.0 2.7 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 EST42733.1 - 0.023 14.8 0.1 0.072 13.1 0.1 1.8 1 0 0 1 1 1 0 Dynamin family MMR_HSR1 PF01926.23 EST42733.1 - 0.026 14.6 0.0 0.079 13.0 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 EST42733.1 - 0.088 12.6 0.3 0.24 11.1 0.3 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain PDEase_I PF00233.19 EST42737.1 - 2.4 7.8 12.4 0.81 9.4 0.8 2.2 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase EF-hand_7 PF13499.6 EST42739.1 - 5.7e-10 39.5 2.2 1.1e-09 38.6 0.4 2.0 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EST42739.1 - 4.2e-08 32.5 1.0 0.011 15.6 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EST42739.1 - 1.2e-07 30.8 7.4 0.00037 19.8 0.6 2.9 3 1 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EST42739.1 - 2.1e-06 27.5 0.6 5.5e-05 22.9 0.2 2.4 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 EST42739.1 - 7.3e-05 22.1 1.7 0.0083 15.6 0.3 2.6 2 0 0 2 2 2 2 EF hand EF-hand_4 PF12763.7 EST42739.1 - 0.0033 17.3 0.6 0.0069 16.3 0.6 1.6 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 EST42739.1 - 0.056 13.3 0.3 0.69 9.8 0.1 2.4 1 1 1 2 2 2 0 EF hand EF-hand_7 PF13499.6 EST42740.1 - 4.8e-10 39.8 1.0 5.5e-10 39.5 0.4 1.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EST42740.1 - 2.5e-09 36.0 2.7 0.00026 20.3 0.7 2.5 2 1 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EST42740.1 - 2.8e-08 33.1 1.0 0.0069 16.2 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EST42740.1 - 1e-06 28.5 0.6 3.1e-05 23.7 0.1 2.3 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 EST42740.1 - 3.3e-05 23.2 1.4 0.0048 16.3 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_4 PF12763.7 EST42740.1 - 0.0022 17.9 0.6 0.0049 16.8 0.5 1.5 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand Pox_VLTF3 PF04947.14 EST42740.1 - 0.05 13.3 0.1 0.055 13.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like EF-hand_10 PF14788.6 EST42740.1 - 0.082 12.8 2.1 0.45 10.4 0.1 2.5 2 1 1 3 3 3 0 EF hand VSP PF03302.13 EST42743.1 - 9.9e-09 34.5 253.6 0.00012 21.0 36.8 9.2 1 1 7 8 8 8 6 Giardia variant-specific surface protein VSP PF03302.13 EST42745.1 - 0.00081 18.4 89.0 0.0046 15.9 24.8 4.1 1 1 3 4 4 4 3 Giardia variant-specific surface protein Bacteriocin_IIc PF10439.9 EST42745.1 - 2.6 8.2 8.9 7.2 6.8 8.9 1.7 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide VSP PF03302.13 EST42746.1 - 2e-09 36.8 266.9 0.0014 17.6 28.9 9.7 1 1 8 9 9 9 6 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST42746.1 - 0.0067 16.6 16.6 0.0067 16.6 16.6 11.7 1 1 10 11 11 11 3 Furin-like repeat, cysteine-rich IL10 PF00726.17 EST42747.1 - 0.061 12.8 0.0 0.061 12.8 0.0 1.1 1 0 0 1 1 1 0 Interleukin 10 VSP PF03302.13 EST42750.1 - 1.9e-07 30.3 80.6 1.6e-05 24.0 36.0 2.7 1 1 1 2 2 2 2 Giardia variant-specific surface protein Bacteriocin_IIc PF10439.9 EST42750.1 - 0.1 12.7 3.5 0.21 11.7 3.5 1.4 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide VSP PF03302.13 EST42751.1 - 4.8e-05 22.4 87.2 0.011 14.6 44.0 3.1 1 1 1 2 2 2 2 Giardia variant-specific surface protein DUF3624 PF12292.8 EST42751.1 - 0.16 12.4 0.2 0.16 12.4 0.2 4.2 5 0 0 5 5 5 0 Protein of unknown function (DUF3624) DUF4200 PF13863.6 EST42752.1 - 0.0034 17.8 24.5 0.0034 17.8 24.5 9.9 4 2 3 9 9 9 4 Domain of unknown function (DUF4200) FlaC_arch PF05377.11 EST42752.1 - 0.084 13.3 0.1 0.084 13.3 0.1 11.3 10 3 2 12 12 12 0 Flagella accessory protein C (FlaC) Myb_DNA-binding PF00249.31 EST42754.1 - 8.6e-10 38.7 0.7 6.4e-08 32.7 0.0 2.4 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST42754.1 - 3.8e-07 30.3 0.6 6.6e-06 26.3 0.1 2.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST42754.1 - 0.043 13.7 0.1 0.12 12.3 0.0 1.7 1 1 0 1 1 1 0 Myb DNA-binding like Myb_DNA-binding PF00249.31 EST42755.1 - 1.2e-13 51.0 0.6 3.7e-10 39.8 0.5 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST42755.1 - 4.7e-06 26.8 1.3 2e-05 24.8 0.2 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST42755.1 - 9.2e-06 25.5 3.3 2.4e-05 24.2 0.5 2.1 1 1 1 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EST42755.1 - 0.001 19.2 1.4 0.0019 18.3 1.4 1.4 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DUF4248 PF14053.6 EST42755.1 - 0.014 15.4 0.9 0.024 14.6 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) Tmemb_9 PF05434.11 EST42755.1 - 0.022 14.7 0.7 0.034 14.0 0.7 1.2 1 0 0 1 1 1 0 TMEM9 Ribosomal_L35Ae PF01247.18 EST42755.1 - 0.056 13.6 0.4 0.078 13.1 0.4 1.3 1 0 0 1 1 1 0 Ribosomal protein L35Ae KGK PF08872.10 EST42755.1 - 0.59 10.6 3.8 0.75 10.3 3.0 1.5 1 1 0 1 1 1 0 KGK domain DUF5528 PF17666.1 EST42755.1 - 0.9 9.5 5.5 0.66 9.9 4.0 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5528) Wzy_C PF04932.15 EST42756.1 - 5.1 6.7 12.7 7e+02 -0.2 12.7 2.1 1 1 0 1 1 1 0 O-Antigen ligase DUF4231 PF14015.6 EST42756.1 - 7.4 7.1 9.9 1.9 9.0 3.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) VSP PF03302.13 EST42758.1 - 0.00015 20.8 87.6 0.037 12.9 44.8 2.8 1 1 1 2 2 2 2 Giardia variant-specific surface protein DUF3624 PF12292.8 EST42758.1 - 0.065 13.6 0.2 0.065 13.6 0.2 3.6 3 2 0 3 3 3 0 Protein of unknown function (DUF3624) VSP PF03302.13 EST42760.1 - 1.4e-12 47.2 326.1 0.00052 19.0 27.3 9.7 1 1 7 8 8 8 6 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST42760.1 - 0.0045 17.1 17.8 0.0045 17.1 17.8 12.0 1 1 11 12 12 12 2 Furin-like repeat, cysteine-rich VSP PF03302.13 EST42761.1 - 0.063 12.1 103.6 0.43 9.4 38.2 4.8 1 1 2 3 3 3 0 Giardia variant-specific surface protein cEGF PF12662.7 EST42761.1 - 0.21 11.5 0.4 0.21 11.5 0.4 6.7 8 0 0 8 8 8 0 Complement Clr-like EGF-like VSP PF03302.13 EST42762.1 - 2.1e-13 49.9 319.2 0.0004 19.3 26.9 10.0 1 1 9 10 10 10 8 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST42762.1 - 0.0036 17.4 17.3 0.0036 17.4 17.3 11.7 1 1 11 12 12 12 2 Furin-like repeat, cysteine-rich VSP PF03302.13 EST42765.1 - 8.8e-05 21.5 38.5 8.8e-05 21.5 38.5 3.9 1 1 1 2 2 2 1 Giardia variant-specific surface protein DUF3624 PF12292.8 EST42765.1 - 0.014 15.8 0.2 0.014 15.8 0.2 3.4 5 1 1 6 6 6 0 Protein of unknown function (DUF3624) Podoplanin PF05808.11 EST42765.1 - 0.3 11.2 2.8 0.6 10.2 2.8 1.5 1 1 0 1 1 1 0 Podoplanin DUF805 PF05656.14 EST42767.1 - 0.0089 16.4 0.0 0.01 16.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF805) PRIMA1 PF16101.5 EST42770.1 - 0.049 13.7 0.2 0.057 13.5 0.2 1.1 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF2810 PF10928.8 EST42770.1 - 0.14 12.2 0.3 0.25 11.4 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2810) Podoplanin PF05808.11 EST42771.1 - 0.00031 20.9 2.8 0.00066 19.8 2.8 1.6 1 1 0 1 1 1 1 Podoplanin Bacteriocin_IIc PF10439.9 EST42771.1 - 0.038 14.1 1.5 0.083 13.0 1.5 1.5 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide PsbX PF06596.11 EST42771.1 - 0.61 10.1 3.0 1.1 9.4 3.0 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) Rdx PF10262.9 EST42773.1 - 4e-09 36.5 0.0 4.4e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Rdx family DUF3084 PF11283.8 EST42775.1 - 0.13 12.2 0.7 0.22 11.5 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3084) SAPS PF04499.15 EST42776.1 - 0.0027 16.6 0.3 0.0033 16.3 0.3 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Sre PF03125.18 EST42777.1 - 0.52 9.4 3.5 0.62 9.2 1.0 1.9 2 0 0 2 2 2 0 C. elegans Sre G protein-coupled chemoreceptor Cript PF10235.9 EST42779.1 - 0.27 11.9 1.6 2.1 9.0 0.1 2.9 2 1 0 2 2 2 0 Microtubule-associated protein CRIPT Myb_DNA-binding PF00249.31 EST42781.1 - 0.00012 22.1 0.0 0.0002 21.5 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST42781.1 - 0.0013 18.9 0.1 0.0022 18.2 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Asp_Glu_race_2 PF14669.6 EST42781.1 - 0.035 13.7 0.1 0.042 13.5 0.1 1.1 1 0 0 1 1 1 0 Putative aspartate racemase DEAD PF00270.29 EST42782.1 - 4.5e-42 143.8 0.4 1.6e-41 142.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EST42782.1 - 1.3e-22 80.2 2.1 3.2e-22 79.0 0.4 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EST42782.1 - 5.3e-07 29.8 0.3 3.5e-06 27.1 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF4217 PF13959.6 EST42782.1 - 0.058 13.6 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4217) ATP-grasp_6 PF18419.1 EST42782.1 - 0.13 11.9 1.5 0.38 10.4 0.1 2.6 3 0 0 3 3 3 0 ATP-grasp-like domain EPOP PF15223.6 EST42782.1 - 0.26 10.6 6.1 0.51 9.6 6.1 1.3 1 0 0 1 1 1 0 Elongin BC and Polycomb repressive complex 2-associated protein GRIM-19 PF06212.12 EST42783.1 - 0.039 13.9 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 GRIM-19 protein BBL5 PF07289.11 EST42784.1 - 1.1e-46 159.4 0.1 1.3e-46 159.2 0.1 1.0 1 0 0 1 1 1 1 Bardet-Biedl syndrome 5 protein Vps36_ESCRT-II PF11605.8 EST42784.1 - 8.5e-07 29.1 0.2 0.00038 20.6 0.5 2.5 2 0 0 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 bPH_3 PF14470.6 EST42784.1 - 0.00024 21.4 0.8 1 9.8 0.0 2.8 2 2 0 2 2 2 2 Bacterial PH domain GRAM PF02893.20 EST42784.1 - 0.0035 17.2 3.4 0.52 10.2 0.2 2.9 3 1 1 4 4 4 2 GRAM domain PH_TFIIH PF08567.11 EST42784.1 - 0.012 15.9 0.0 0.65 10.4 0.0 2.7 2 0 0 2 2 2 0 TFIIH p62 subunit, N-terminal domain ArgoMid PF16487.5 EST42787.1 - 0.11 12.8 0.1 0.32 11.3 0.1 1.8 1 0 0 1 1 1 0 Mid domain of argonaute ATP-grasp_5 PF13549.6 EST42788.1 - 6.7e-67 225.2 0.2 1e-66 224.6 0.2 1.3 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 EST42788.1 - 2.2e-51 173.3 0.2 1.3e-50 170.8 0.0 2.4 3 0 0 3 3 3 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EST42788.1 - 4.6e-22 78.7 0.2 1.5e-21 77.0 0.1 2.0 2 0 0 2 2 2 1 CoA binding domain CoA_binding PF02629.19 EST42788.1 - 6.4e-12 46.0 0.3 1.8e-11 44.5 0.3 1.9 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 EST42788.1 - 4.2e-06 26.5 0.4 9.8e-06 25.3 0.4 1.7 1 0 0 1 1 1 1 ATP-grasp domain Lbh PF15317.6 EST42789.1 - 0.063 14.1 0.3 0.1 13.5 0.3 1.4 1 0 0 1 1 1 0 Cardiac transcription factor regulator, Developmental protein DSL PF01414.19 EST42790.1 - 0.012 15.9 1.1 0.02 15.2 0.2 1.9 2 1 0 2 2 2 0 Delta serrate ligand CDH-cyt PF16010.5 EST42791.1 - 0.23 11.1 1.8 0.58 9.8 0.1 2.4 2 1 1 3 3 3 0 Cytochrome domain of cellobiose dehydrogenase Asparaginase PF00710.20 EST42794.1 - 5.1e-55 186.0 0.0 6.7e-55 185.6 0.0 1.1 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 EST42794.1 - 8.3e-23 80.8 0.0 1.2e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain START PF01852.19 EST42794.1 - 0.22 10.9 0.0 0.32 10.4 0.0 1.2 1 0 0 1 1 1 0 START domain EF-hand_7 PF13499.6 EST42795.1 - 0.0063 16.9 0.1 0.42 11.1 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EST42795.1 - 0.0073 16.2 0.1 0.065 13.2 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain DUF2004 PF09406.10 EST42795.1 - 0.0093 16.3 2.5 0.21 11.9 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2004) EF-hand_1 PF00036.32 EST42795.1 - 0.089 12.4 0.1 0.25 11.0 0.1 1.8 1 0 0 1 1 1 0 EF hand ROS_MUCR PF05443.11 EST42795.1 - 0.28 11.2 2.7 6.1 6.9 0.1 3.3 3 1 0 3 3 3 0 ROS/MUCR transcriptional regulator protein DUF2624 PF11116.8 EST42795.1 - 1.5 9.8 7.5 0.35 11.8 1.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2624) STELLO PF03385.17 EST42796.1 - 0.032 13.0 0.4 0.039 12.8 0.4 1.0 1 0 0 1 1 1 0 STELLO glycosyltransferases DUF3970 PF13113.6 EST42796.1 - 0.063 13.5 0.3 0.077 13.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3970) Sulfatase PF00884.23 EST42798.1 - 8.9e-18 64.7 2.2 1.3e-17 64.2 2.2 1.2 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 EST42798.1 - 0.00035 19.3 0.0 0.00075 18.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF229) UPF0029 PF01205.19 EST42799.1 - 7.9e-21 74.4 0.0 1.5e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Adaptin_N PF01602.20 EST42800.1 - 1e-21 77.1 28.3 4.2e-12 45.4 0.7 2.7 2 1 0 3 3 3 2 Adaptin N terminal region Ank_2 PF12796.7 EST42802.1 - 1e-23 83.7 0.4 7.2e-14 52.2 0.2 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EST42802.1 - 5.8e-11 42.7 0.3 3e-09 37.2 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EST42802.1 - 1.5e-08 34.7 0.0 0.00085 19.7 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EST42802.1 - 1e-07 31.7 0.0 0.0051 17.2 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EST42802.1 - 7.5e-07 29.3 0.0 0.014 15.7 0.0 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) IL3 PF02059.15 EST42802.1 - 0.017 15.2 4.9 1.7 8.8 0.7 2.3 2 0 0 2 2 2 0 Interleukin-3 RNA_pol_Rpb2_5 PF04567.17 EST42802.1 - 0.1 13.2 1.6 0.31 11.6 1.6 1.9 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 5 bZIP_1 PF00170.21 EST42802.1 - 0.3 11.2 5.4 0.55 10.4 0.3 2.6 2 1 1 3 3 3 0 bZIP transcription factor Sedlin_N PF04628.13 EST42803.1 - 4e-06 27.0 1.8 4.8e-06 26.7 1.8 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region ATLF PF07737.11 EST42803.1 - 0.0078 15.5 0.2 0.011 15.0 0.2 1.3 1 0 0 1 1 1 1 Anthrax toxin lethal factor, N- and C-terminal domain Interferon PF00143.19 EST42803.1 - 0.11 12.7 0.8 0.18 12.0 0.6 1.5 1 1 0 1 1 1 0 Interferon alpha/beta domain DUF4845 PF16137.5 EST42806.1 - 0.026 15.4 2.9 0.19 12.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4845) DUF4320 PF14208.6 EST42806.1 - 0.076 13.1 2.2 0.089 12.9 0.2 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4320) SIR2 PF02146.17 EST42807.1 - 3.8e-13 49.8 0.0 8.6e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 Sir2 family bZIP_1 PF00170.21 EST42810.1 - 0.79 9.9 9.2 2.5 8.2 1.8 2.2 2 0 0 2 2 2 0 bZIP transcription factor Arf PF00025.21 EST42811.1 - 5.9e-48 162.6 0.1 6.7e-48 162.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EST42811.1 - 1.8e-11 43.9 1.0 1e-06 28.2 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EST42811.1 - 5.6e-11 42.7 0.0 8.3e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EST42811.1 - 1.4e-09 37.8 0.0 1.7e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EST42811.1 - 5.4e-08 32.5 0.0 7.6e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EST42811.1 - 1.4e-05 24.6 0.0 1.9e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EST42811.1 - 4.7e-05 23.4 0.0 7.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EST42811.1 - 0.0012 18.4 0.0 0.015 14.8 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 EST42811.1 - 0.022 15.0 0.0 0.039 14.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 EST42811.1 - 0.039 13.3 0.0 0.22 10.8 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_16 PF13191.6 EST42811.1 - 0.048 14.0 0.0 0.063 13.7 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.17 EST42811.1 - 0.093 12.5 0.0 5.2 6.8 0.0 2.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein DUF3088 PF11287.8 EST42811.1 - 0.11 12.2 0.0 0.43 10.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3088) DSPc PF00782.20 EST42812.1 - 1.5e-15 57.2 0.2 3e-15 56.2 0.2 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EST42812.1 - 0.058 13.5 0.5 0.6 10.2 0.0 2.5 3 0 0 3 3 3 0 Inositol hexakisphosphate Hom_end_hint PF05203.16 EST42813.1 - 0.1 12.6 0.5 0.15 12.0 0.5 1.4 1 1 0 1 1 1 0 Hom_end-associated Hint SMC_N PF02463.19 EST42814.1 - 6.7e-09 35.5 35.7 1.1e-08 34.9 0.3 4.1 3 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EST42814.1 - 1.2e-08 35.1 29.9 1.2e-08 35.1 29.9 4.7 1 1 2 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 EST42814.1 - 1.6e-06 27.7 0.0 4.8e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_27 PF13514.6 EST42814.1 - 0.00015 21.4 0.0 0.00015 21.4 0.0 3.4 4 1 0 4 4 4 1 AAA domain AAA_16 PF13191.6 EST42814.1 - 0.01 16.2 0.0 0.01 16.2 0.0 3.0 3 2 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 EST42814.1 - 0.065 13.5 2.0 0.69 10.2 0.0 3.4 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EST42814.1 - 0.1 12.8 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.18 EST42814.1 - 0.11 11.8 2.0 2.4 7.5 0.0 3.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family DUF5461 PF17545.2 EST42814.1 - 0.18 12.1 1.8 0.67 10.3 1.2 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5461) AAA_23 PF13476.6 EST42814.1 - 5.3 7.5 134.0 0.31 11.5 69.9 6.5 2 2 0 2 2 2 0 AAA domain DUF4471 PF14740.6 EST42815.1 - 7.2e-16 58.3 6.0 1e-10 41.3 0.6 2.4 2 1 1 3 3 3 2 Domain of unknown function (DUF4471) DUF4470 PF14737.6 EST42815.1 - 0.0022 18.1 0.0 0.0062 16.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) ATP-grasp_5 PF13549.6 EST42817.1 - 2.8e-39 134.9 0.0 4.1e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 EST42817.1 - 2.9e-23 82.2 0.3 1.4e-22 80.0 0.3 2.1 1 1 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EST42817.1 - 7.5e-10 39.3 0.0 1.7e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 EST42817.1 - 0.13 13.0 0.0 5.2 7.8 0.0 3.1 3 0 0 3 3 3 0 CoA binding domain Myb_DNA-binding PF00249.31 EST42819.1 - 5.5e-17 61.7 0.9 2.1e-10 40.7 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST42819.1 - 1.2e-16 60.7 2.4 2.2e-12 47.0 0.2 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EST42819.1 - 1.3e-05 25.2 0.5 0.048 13.7 0.0 3.0 1 1 1 3 3 3 2 SLIDE SARAF PF06682.12 EST42820.1 - 1.1e-23 84.4 0.1 1.5e-23 84.0 0.1 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis TNFR_16_TM PF18422.1 EST42820.1 - 0.014 15.3 1.8 0.04 13.9 1.8 1.7 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Med31 PF05669.12 EST42821.1 - 0.0083 16.1 0.1 0.023 14.7 0.1 1.7 1 0 0 1 1 1 1 SOH1 SwrA PF17423.2 EST42821.1 - 0.028 14.4 0.5 0.28 11.2 0.0 2.8 2 1 1 3 3 3 0 Swarming motility protein UBA_2 PF08587.11 EST42821.1 - 0.047 13.8 0.1 0.14 12.3 0.1 1.8 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) YgaB PF14182.6 EST42821.1 - 0.85 10.0 7.7 6.6 7.2 4.8 2.7 2 0 0 2 2 2 0 YgaB-like protein Pkinase PF00069.25 EST42822.1 - 5.9e-53 179.9 0.3 7.4e-53 179.6 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST42822.1 - 4.1e-28 98.4 0.1 5.5e-28 98.0 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EST42822.1 - 2e-05 24.0 0.1 0.00075 18.9 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EST42822.1 - 0.0031 16.5 0.1 0.0062 15.5 0.1 1.5 1 1 0 1 1 1 1 Haspin like kinase domain S-AdoMet_synt_C PF02773.16 EST42823.1 - 1.5e-54 183.7 1.1 3.9e-54 182.4 0.0 2.2 3 0 0 3 3 3 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 EST42823.1 - 3.9e-35 120.7 0.8 1.5e-31 109.1 0.0 2.8 2 1 1 3 3 3 2 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 EST42823.1 - 2.1e-33 114.9 0.3 7.3e-33 113.2 0.1 2.0 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain Lactamase_B_3 PF13483.6 EST42823.1 - 0.011 15.6 0.2 0.024 14.5 0.2 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain NCE101 PF11654.8 EST42823.1 - 0.048 13.4 0.0 0.26 11.0 0.0 2.1 2 0 0 2 2 2 0 Non-classical export protein 1 Staphostatin_A PF09022.10 EST42823.1 - 0.062 13.2 0.3 5.2 7.0 0.0 2.3 2 0 0 2 2 2 0 Staphostatin A Bromodomain PF00439.25 EST42824.1 - 0.0001 22.3 0.0 0.032 14.3 0.0 2.9 3 0 0 3 3 3 2 Bromodomain AMP-binding PF00501.28 EST42825.1 - 3e-75 253.4 0.0 1.8e-74 250.8 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EST42825.1 - 0.014 16.4 0.0 0.037 15.0 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain RtcB PF01139.17 EST42826.1 - 7.7e-17 61.6 0.0 1.5e-16 60.6 0.0 1.4 1 1 0 1 1 1 1 tRNA-splicing ligase RtcB Furin-like_2 PF15913.5 EST42830.1 - 0.00066 19.8 30.2 0.00066 19.8 30.2 9.6 2 2 6 8 8 8 4 Furin-like repeat, cysteine-rich FHIPEP PF00771.20 EST42830.1 - 1.1 7.6 2.2 1.5 7.2 2.2 1.1 1 0 0 1 1 1 0 FHIPEP family DUF5408 PF17402.2 EST42832.1 - 0.24 11.3 0.8 0.34 10.8 0.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5408) RNase_Zc3h12a PF11977.8 EST42839.1 - 0.13 12.0 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain MFS_1 PF07690.16 EST42840.1 - 7.1e-29 100.8 27.9 9.6e-29 100.4 27.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EST42840.1 - 1.7e-12 46.9 22.8 2.3e-12 46.5 10.2 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 EST42840.1 - 2.7e-08 32.8 35.0 5.1e-05 22.0 10.5 2.4 1 1 1 2 2 2 2 MFS/sugar transport protein OST-HTH PF12872.7 EST42843.1 - 0.11 12.4 0.1 0.31 10.9 0.1 1.8 1 1 1 2 2 2 0 OST-HTH/LOTUS domain CspB_prodomain PF18425.1 EST42844.1 - 0.029 14.4 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Csp protease B prodomain APC_rep PF18797.1 EST42845.1 - 0.083 13.8 0.1 0.2 12.6 0.0 1.7 1 1 1 2 2 2 0 Adenomatous polyposis coli (APC) repeat DUF2122 PF09895.9 EST42845.1 - 0.15 12.4 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 RecB-family nuclease (DUF2122) Spore_III_AB PF09548.10 EST42845.1 - 0.2 11.8 1.1 0.22 11.6 1.1 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) ROK PF00480.20 EST42849.1 - 2.8e-72 243.7 4.0 3.4e-72 243.4 4.0 1.0 1 0 0 1 1 1 1 ROK family FGGY_N PF00370.21 EST42849.1 - 1.4e-05 24.8 0.0 2.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Hydant_A_N PF05378.13 EST42849.1 - 9.8e-05 22.1 0.2 0.00018 21.3 0.2 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase N-terminal region BcrAD_BadFG PF01869.20 EST42849.1 - 0.0017 17.9 0.6 0.044 13.3 0.3 2.1 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family PMI_typeI PF01238.21 EST42850.1 - 1.9e-10 40.5 0.2 1.4e-07 31.1 0.3 3.1 1 1 1 2 2 2 2 Phosphomannose isomerase type I Cupin_2 PF07883.11 EST42850.1 - 0.0016 18.1 0.1 0.064 13.0 0.0 2.5 2 0 0 2 2 2 1 Cupin domain Podoplanin PF05808.11 EST42851.1 - 0.001 19.2 3.6 0.001 19.2 3.6 2.1 2 1 0 2 2 2 1 Podoplanin Syndecan PF01034.20 EST42851.1 - 0.097 12.6 1.9 0.17 11.8 1.9 1.3 1 0 0 1 1 1 0 Syndecan domain Insulin_TMD PF17870.1 EST42851.1 - 0.89 9.7 5.3 1.8 8.7 5.3 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment cEGF PF12662.7 EST42851.1 - 1.7 8.7 26.9 0.56 10.2 0.2 6.5 5 1 1 6 6 6 0 Complement Clr-like EGF-like Myb_DNA-binding PF00249.31 EST42854.1 - 1.1e-05 25.6 0.5 1.4e-05 25.2 0.5 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EST42854.1 - 3e-05 24.1 0.3 3.7e-05 23.8 0.3 1.1 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_6 PF13921.6 EST42854.1 - 0.0054 17.0 0.1 0.0068 16.6 0.1 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST42854.1 - 0.051 13.5 0.0 0.053 13.4 0.0 1.1 1 0 0 1 1 1 0 Myb DNA-binding like DUF3799 PF12684.7 EST42855.1 - 0.047 13.5 6.2 0.055 13.2 5.4 1.5 1 1 0 1 1 1 0 PDDEXK-like domain of unknown function (DUF3799) SF3a60_bindingd PF12108.8 EST42857.1 - 0.32 10.9 1.4 0.76 9.7 0.1 2.1 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain VSP PF03302.13 EST42858.1 - 2e-07 30.3 110.9 0.0027 16.6 30.3 5.3 1 1 4 5 5 5 4 Giardia variant-specific surface protein VSP PF03302.13 EST42859.1 - 4.9e-08 32.2 99.6 2e-05 23.6 33.8 3.9 1 1 3 4 4 4 4 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST42859.1 - 0.016 15.4 76.1 0.035 14.3 11.7 4.9 1 1 3 4 4 4 0 Furin-like repeat, cysteine-rich SMC_Nse1 PF07574.13 EST42861.1 - 0.11 12.3 1.7 0.28 11.0 1.5 1.7 1 1 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex DUF4401 PF14351.6 EST42862.1 - 0.095 12.0 0.2 0.13 11.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) VSP PF03302.13 EST42863.1 - 9.8e-14 51.0 167.8 0.00019 20.4 22.1 7.1 1 1 6 7 7 7 5 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST42863.1 - 0.0045 17.1 18.4 0.0045 17.1 18.4 8.9 1 1 7 9 9 9 3 Furin-like repeat, cysteine-rich Podoplanin PF05808.11 EST42863.1 - 0.024 14.7 0.1 0.04 14.0 0.1 1.3 1 0 0 1 1 1 0 Podoplanin Chordopox_A13L PF05961.11 EST42863.1 - 0.081 13.2 0.6 0.15 12.3 0.6 1.4 1 0 0 1 1 1 0 Chordopoxvirus A13L protein DUF4366 PF14283.6 EST42863.1 - 0.11 12.6 0.1 0.34 11.0 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) VSP PF03302.13 EST42868.1 - 6.5e-06 25.2 261.2 0.0022 16.9 34.4 8.4 1 1 7 8 8 8 5 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST42868.1 - 0.011 15.9 16.5 0.011 15.9 16.5 11.7 1 1 9 10 10 10 0 Furin-like repeat, cysteine-rich CobN-Mg_chel PF02514.16 EST42869.1 - 4.1 5.0 12.9 4.4 4.9 12.9 1.0 1 0 0 1 1 1 0 CobN/Magnesium Chelatase MRP-L46 PF11788.8 EST42869.1 - 5.5 7.8 12.2 11 6.8 12.2 1.8 1 1 0 1 1 1 0 39S mitochondrial ribosomal protein L46 VSP PF03302.13 EST42870.1 - 1.8e-12 46.9 261.8 0.0025 16.8 20.6 9.8 1 1 8 9 9 9 9 Giardia variant-specific surface protein DUF4690 PF15756.5 EST42870.1 - 2.3 8.9 4.2 1.7 9.3 0.3 2.8 3 0 0 3 3 3 0 Small Novel Rich in Cartilage RNA_pol_Rpb2_5 PF04567.17 EST42872.1 - 0.73 10.4 3.3 0.85 10.2 0.3 2.6 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 5 DUF4183 PF13799.6 EST42873.1 - 0.042 13.6 0.4 0.65 9.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4183) TPR_MLP1_2 PF07926.12 EST42874.1 - 6.9 6.7 11.8 13 5.9 0.0 3.5 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein RRT14 PF17075.5 EST42877.1 - 0.29 11.2 13.6 0.73 9.9 13.6 1.6 1 0 0 1 1 1 0 Regular of rDNA transcription protein 14 Fib_alpha PF08702.10 EST42877.1 - 5.8 7.1 10.0 19 5.4 10.0 2.0 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Phage_Coat_B PF05356.11 EST42878.1 - 7.4 6.6 6.6 1.7 8.6 2.4 2.2 2 1 0 2 2 2 0 Phage Coat protein B VSP PF03302.13 EST42880.1 - 9e-09 34.7 261.4 1.1e-05 24.5 23.8 9.7 1 1 7 8 8 8 6 Giardia variant-specific surface protein Podoplanin PF05808.11 EST42880.1 - 0.16 12.0 2.9 0.26 11.4 0.1 2.6 3 0 0 3 3 3 0 Podoplanin VSP PF03302.13 EST42882.1 - 0.00013 20.9 4.5 0.00014 20.8 4.5 1.0 1 0 0 1 1 1 1 Giardia variant-specific surface protein Insulin_TMD PF17870.1 EST42882.1 - 0.017 15.1 0.2 0.021 14.9 0.2 1.2 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF4366 PF14283.6 EST42882.1 - 0.02 14.9 0.2 0.021 14.9 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF3352 PF11832.8 EST42882.1 - 0.054 12.2 0.4 0.061 12.0 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3352) CYYR1 PF10873.8 EST42882.1 - 0.066 13.7 1.6 0.063 13.7 1.6 1.1 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 PTP_tm PF18861.1 EST42882.1 - 0.16 11.9 1.8 0.19 11.7 1.8 1.1 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J FHIPEP PF00771.20 EST42882.1 - 0.2 10.1 2.8 0.23 9.9 2.8 1.1 1 0 0 1 1 1 0 FHIPEP family GAPT PF11770.8 EST42882.1 - 0.25 11.2 0.1 0.27 11.1 0.1 1.1 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) Myb_DNA-binding PF00249.31 EST42883.1 - 3.2e-08 33.6 0.1 6.1e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST42883.1 - 2.8e-07 30.7 1.0 3.9e-07 30.2 1.0 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST42883.1 - 0.0055 16.6 1.0 0.0069 16.3 1.0 1.3 1 1 0 1 1 1 1 Myb DNA-binding like UPF0556 PF10572.9 EST42883.1 - 0.019 14.4 0.1 0.022 14.2 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0556 PI_PP_I PF18363.1 EST42883.1 - 0.063 13.5 1.4 0.11 12.7 1.3 1.5 1 1 0 1 1 1 0 Phosphoinositide phosphatase insertion domain Sugar_tr PF00083.24 EST42884.1 - 3.5e-59 200.9 34.4 1.6e-39 136.1 13.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EST42884.1 - 7.7e-17 61.2 54.1 5e-14 52.0 30.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EST42884.1 - 0.00054 19.4 8.0 0.00054 19.4 8.0 2.2 1 1 1 2 2 2 1 Uncharacterised MFS-type transporter YbfB VSP PF03302.13 EST42885.1 - 0.0012 17.8 49.6 1.5 7.6 13.4 3.2 1 1 1 2 2 2 2 Giardia variant-specific surface protein DUF4366 PF14283.6 EST42885.1 - 0.012 15.6 0.3 0.017 15.2 0.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) VSP PF03302.13 EST42886.1 - 0.0079 15.1 5.2 0.0079 15.1 5.2 10.5 2 1 8 10 10 10 4 Giardia variant-specific surface protein Podoplanin PF05808.11 EST42886.1 - 8.9 6.4 5.4 47 4.0 5.4 2.3 1 1 0 1 1 1 0 Podoplanin bZIP_1 PF00170.21 EST42887.1 - 2.2 8.4 25.5 0.23 11.6 2.4 5.3 4 3 2 6 6 6 0 bZIP transcription factor Pkinase PF00069.25 EST42889.1 - 0.014 14.8 0.0 0.016 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Pkinase PF00069.25 EST42890.1 - 2.6e-39 135.2 0.0 5.1e-39 134.2 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST42890.1 - 7.1e-15 55.0 0.0 1.1e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Yop-YscD_ppl PF16693.5 EST42891.1 - 0.0039 16.7 0.4 0.066 12.6 0.1 2.1 1 1 1 2 2 2 1 Inner membrane component of T3SS, periplasmic domain Fer4_24 PF18109.1 EST42891.1 - 0.0046 17.2 9.2 3.3e+02 1.7 0.0 7.6 8 0 0 8 8 8 0 Ferredoxin I 4Fe-4S cluster domain Ribosomal_TL5_C PF14693.6 EST42891.1 - 0.027 14.8 2.3 3.6 8.0 0.2 2.2 1 1 1 2 2 2 0 Ribosomal protein TL5, C-terminal domain FmiP_Thoc5 PF09766.9 EST42891.1 - 0.32 10.3 4.0 23 4.1 0.1 3.4 1 1 4 5 5 5 0 Fms-interacting protein/Thoc5 dCMP_cyt_deam_1 PF00383.23 EST42892.1 - 0.00076 19.3 0.0 0.00095 19.0 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Pkinase PF00069.25 EST42893.1 - 8.1e-51 172.9 0.0 9.5e-51 172.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST42893.1 - 1.3e-17 64.0 0.0 1.9e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.16 EST42893.1 - 0.028 14.6 0.0 0.057 13.6 0.0 1.5 1 0 0 1 1 1 0 ABC1 family Syntaxin-6_N PF09177.11 EST42894.1 - 0.01 16.4 1.5 0.39 11.3 1.9 2.8 2 1 0 2 2 2 0 Syntaxin 6, N-terminal RolB_RolC PF02027.17 EST42894.1 - 0.044 13.4 1.3 0.069 12.8 0.6 1.6 1 1 1 2 2 2 0 RolB/RolC glucosidase family PDH PF02153.17 EST42894.1 - 0.051 12.6 0.1 0.08 11.9 0.1 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase NikR_C PF08753.11 EST42894.1 - 0.22 11.7 1.0 0.49 10.6 1.0 1.6 1 0 0 1 1 1 0 NikR C terminal nickel binding domain Baculo_PEP_C PF04513.12 EST42894.1 - 0.66 10.0 4.3 5.6 7.0 3.4 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pkinase PF00069.25 EST42895.1 - 5.6e-22 78.4 0.1 3.6e-17 62.6 0.0 2.5 2 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EST42895.1 - 3.7e-08 33.0 0.0 2.8e-06 26.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase dCMP_cyt_deam_1 PF00383.23 EST42896.1 - 5.7e-09 35.8 1.9 6.5e-09 35.6 1.9 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 EST42896.1 - 7.9e-05 22.9 0.3 0.043 14.0 0.0 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 EST42896.1 - 0.035 13.7 3.6 0.087 12.4 0.3 2.0 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases Got1 PF04178.12 EST42897.1 - 0.0062 17.0 10.5 0.067 13.6 2.5 2.1 1 1 1 2 2 2 2 Got1/Sft2-like family DUF3040 PF11239.8 EST42897.1 - 0.041 14.2 2.8 0.041 14.2 2.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Form-deh_trans PF09163.11 EST42897.1 - 0.086 12.6 0.4 0.086 12.6 0.4 2.7 3 1 0 3 3 3 0 Formate dehydrogenase N, transmembrane DUF3989 PF13150.6 EST42897.1 - 0.18 11.5 0.6 0.63 9.8 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3989) TssN PF17555.2 EST42897.1 - 0.24 10.7 4.9 0.29 10.5 4.9 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF751 PF05421.11 EST42897.1 - 5.3 7.8 9.4 10 6.9 0.8 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF751) DUF3040 PF11239.8 EST42900.1 - 0.074 13.3 3.4 0.11 12.7 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) dCMP_cyt_deam_1 PF00383.23 EST42901.1 - 4.5e-16 58.6 1.2 5.4e-16 58.3 1.2 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 EST42901.1 - 5.7e-12 46.0 2.4 8.3e-10 39.0 0.6 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 EST42901.1 - 0.03 13.9 2.9 0.098 12.3 0.2 2.0 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases Ribosomal_L38e PF01781.18 EST42903.1 - 9.9e-11 41.6 1.0 1.1e-10 41.4 1.0 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Integrase_Zn PF02022.19 EST42903.1 - 0.042 13.8 0.1 0.083 12.9 0.1 1.4 1 0 0 1 1 1 0 Integrase Zinc binding domain YcaO_C PF18381.1 EST42903.1 - 0.093 12.6 0.0 0.12 12.3 0.0 1.3 1 1 0 1 1 1 0 YcaO cyclodehydratase C-terminal domain Ribosomal_L23 PF00276.20 EST42904.1 - 2.5e-13 50.2 0.9 7.4e-13 48.7 0.9 1.8 1 1 0 1 1 1 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.13 EST42904.1 - 3.7e-08 33.4 3.3 6.8e-08 32.6 3.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain ResIII PF04851.15 EST42904.1 - 0.11 12.4 0.1 0.16 11.9 0.1 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Dynamin_N PF00350.23 EST42905.1 - 0.071 13.2 0.1 0.091 12.8 0.1 1.1 1 0 0 1 1 1 0 Dynamin family Cation_efflux PF01545.21 EST42906.1 - 1.3e-07 31.5 0.3 1.7e-07 31.2 0.3 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EST42906.1 - 1.5e-07 31.4 0.1 2.1e-07 31.0 0.1 1.2 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter WSC PF01822.19 EST42906.1 - 0.042 14.0 0.0 0.089 13.0 0.0 1.5 1 0 0 1 1 1 0 WSC domain His_Phos_2 PF00328.22 EST42911.1 - 0.058 12.7 0.0 0.08 12.3 0.0 1.1 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Peptidase_C97 PF05903.14 EST42912.1 - 6.4e-26 91.0 0.2 6.4e-26 91.0 0.2 1.6 2 0 0 2 2 2 1 PPPDE putative peptidase domain His_Phos_2 PF00328.22 EST42913.1 - 1e-07 31.7 0.0 5.2e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Orf78 PF06024.12 EST42913.1 - 0.12 12.7 1.9 0.22 11.8 1.9 1.4 1 0 0 1 1 1 0 Orf78 (ac78) PIG-U PF06728.13 EST42913.1 - 0.12 11.4 0.4 0.19 10.8 0.0 1.4 2 0 0 2 2 2 0 GPI transamidase subunit PIG-U DUF3043 PF11241.8 EST42913.1 - 2.8 7.9 4.1 22 5.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) Shisa PF13908.6 EST42914.1 - 8.6e-05 22.9 1.0 8.8e-05 22.8 1.0 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Prominin PF05478.11 EST42914.1 - 0.12 10.4 6.6 0.12 10.3 6.6 1.0 1 0 0 1 1 1 0 Prominin Comm PF15957.5 EST42914.1 - 0.92 9.9 5.7 1.1 9.7 5.4 1.3 1 1 0 1 1 1 0 Commissureless DisA_N PF02457.16 EST42919.1 - 0.099 12.2 0.2 0.2 11.3 0.2 1.4 1 0 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding WDCP PF15390.6 EST42924.1 - 0.0028 16.1 3.6 0.0045 15.5 3.5 1.4 1 1 0 1 1 1 1 WD repeat and coiled-coil-containing protein family VPS13_C PF16909.5 EST42924.1 - 0.0078 16.0 0.6 0.042 13.6 0.2 2.1 1 1 1 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal Methyltransf_16 PF10294.9 EST42925.1 - 2.1e-15 56.9 0.0 2.7e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EST42925.1 - 1.2e-07 31.7 0.0 1.6e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EST42925.1 - 2.6e-05 24.8 0.0 0.00014 22.4 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EST42925.1 - 2.8e-05 23.7 0.0 3.9e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EST42925.1 - 0.00017 22.3 0.0 0.00036 21.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.15 EST42925.1 - 0.001 18.4 0.0 0.002 17.5 0.0 1.7 1 1 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_25 PF13649.6 EST42925.1 - 0.0032 18.1 0.0 0.016 15.9 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EST42925.1 - 0.0043 16.5 0.0 0.0054 16.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.12 EST42925.1 - 0.0057 15.8 0.0 0.008 15.3 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_31 PF13847.6 EST42925.1 - 0.017 14.9 0.1 0.11 12.3 0.1 2.2 1 1 0 1 1 1 0 Methyltransferase domain CnrY PF17524.2 EST42928.1 - 0.03 14.5 0.0 0.032 14.4 0.0 1.0 1 0 0 1 1 1 0 Anti-sigma factor CnrY Luteo_Vpg PF01659.16 EST42929.1 - 0.13 12.7 0.0 0.89 9.9 0.0 2.0 2 0 0 2 2 2 0 Luteovirus putative VPg genome linked protein PPV_E1_N PF00524.18 EST42930.1 - 0.092 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 E1 Protein, N terminal domain Leu_zip PF15294.6 EST42935.1 - 4.4e-10 39.5 12.2 1.7e-06 27.8 4.6 2.1 1 1 1 2 2 2 2 Leucine zipper PKcGMP_CC PF16808.5 EST42935.1 - 2.3e-06 27.3 7.7 0.0011 18.7 0.6 3.1 3 0 0 3 3 3 2 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF3708 PF12501.8 EST42935.1 - 0.058 13.2 0.6 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter TMF_TATA_bd PF12325.8 EST42935.1 - 0.56 10.5 13.1 0.76 10.0 5.0 3.0 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding LMBR1 PF04791.16 EST42935.1 - 1.8 7.4 4.7 2 7.2 4.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Pox_A_type_inc PF04508.12 EST42935.1 - 3 7.9 5.8 94 3.1 0.0 3.9 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat DUF2203 PF09969.9 EST42935.1 - 4.8 7.9 7.7 4.3 8.1 0.4 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Med9 PF07544.13 EST42937.1 - 0.058 13.5 0.0 0.079 13.1 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Alfin PF12165.8 EST42938.1 - 0.17 11.5 0.0 0.63 9.7 0.0 1.8 1 1 1 2 2 2 0 Alfin PP2C PF00481.21 EST42940.1 - 5.5e-20 72.1 0.0 8e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EST42940.1 - 1.1e-08 35.0 0.0 1.8e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Myb_DNA-binding PF00249.31 EST42941.1 - 1.9e-09 37.6 0.2 2.7e-09 37.1 0.2 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST42941.1 - 1.3e-07 31.7 0.5 1.6e-07 31.4 0.5 1.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST42941.1 - 5.2e-06 26.3 0.2 5.9e-06 26.1 0.2 1.2 1 0 0 1 1 1 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EST42941.1 - 0.0011 19.1 0.6 0.0014 18.8 0.6 1.4 1 1 0 1 1 1 1 SANT/Myb-like domain of DAMP1 HAD_2 PF13419.6 EST42943.1 - 3.8e-26 92.2 0.0 5.2e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EST42943.1 - 7e-11 42.8 0.0 2.3e-08 34.6 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EST42943.1 - 0.00077 19.5 0.0 0.0011 19.0 0.0 1.2 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EST42943.1 - 0.0013 19.1 0.0 0.0023 18.4 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase LDcluster4 PF18306.1 EST42943.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 SLOG cluster4 family DivIC PF04977.15 EST42944.1 - 0.0056 16.4 3.5 0.008 15.9 3.5 1.3 1 0 0 1 1 1 1 Septum formation initiator Nnf1 PF03980.14 EST42944.1 - 0.0069 16.7 0.5 0.0079 16.6 0.5 1.3 1 1 0 1 1 1 1 Nnf1 HALZ PF02183.18 EST42944.1 - 0.02 15.1 0.6 0.038 14.2 0.6 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper ZapB PF06005.12 EST42944.1 - 0.029 14.8 4.5 0.046 14.2 4.5 1.3 1 0 0 1 1 1 0 Cell division protein ZapB FlaC_arch PF05377.11 EST42944.1 - 0.032 14.6 0.7 0.12 12.8 0.8 1.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) NYD-SP28_assoc PF14775.6 EST42944.1 - 0.11 12.6 1.3 0.19 11.9 1.3 1.4 1 0 0 1 1 1 0 Sperm tail C-terminal domain Bap31_Bap29_C PF18035.1 EST42944.1 - 0.13 12.3 4.2 0.14 12.2 3.3 1.5 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF3138 PF11336.8 EST42944.1 - 0.15 10.6 0.0 0.18 10.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Swi5 PF07061.11 EST42944.1 - 0.25 11.4 3.1 0.47 10.6 2.4 1.7 2 0 0 2 2 2 0 Swi5 Asparaginase PF00710.20 EST42948.1 - 0.1 12.1 0.1 0.22 11.0 0.0 1.5 1 1 0 1 1 1 0 Asparaginase, N-terminal SCAPER_N PF16501.5 EST42949.1 - 0.046 13.7 0.1 0.073 13.1 0.1 1.2 1 0 0 1 1 1 0 S phase cyclin A-associated protein in the endoplasmic reticulum HALZ PF02183.18 EST42950.1 - 0.0015 18.7 4.9 0.027 14.7 0.2 3.0 2 0 0 2 2 2 2 Homeobox associated leucine zipper RepC PF06504.11 EST42950.1 - 0.017 14.4 0.3 0.019 14.2 0.3 1.3 1 0 0 1 1 1 0 Replication protein C (RepC) Speriolin_N PF15058.6 EST42950.1 - 1.2 9.2 3.7 2.2 8.4 0.5 2.1 1 1 0 2 2 2 0 Speriolin N terminus TMF_TATA_bd PF12325.8 EST42951.1 - 0.026 14.8 8.4 0.033 14.4 7.8 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding FAM76 PF16046.5 EST42951.1 - 1.1 8.5 8.8 1.4 8.2 8.8 1.1 1 0 0 1 1 1 0 FAM76 protein Jnk-SapK_ap_N PF09744.9 EST42951.1 - 1.2 9.3 12.9 2 8.7 9.5 2.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 YabA PF06156.13 EST42951.1 - 2.8 8.6 11.7 1.5 9.5 8.1 2.3 1 1 0 2 2 2 0 Initiation control protein YabA Pkinase PF00069.25 EST42952.1 - 5.1e-59 199.8 0.3 7.2e-59 199.3 0.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST42952.1 - 3.3e-39 134.7 0.1 6e-39 133.9 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EST42952.1 - 3e-07 29.6 0.2 9e-07 28.0 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 EST42952.1 - 0.014 15.0 0.2 2.2 7.9 0.1 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EST42952.1 - 0.086 12.2 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MetOD1 PF18546.1 EST42953.1 - 0.034 14.1 2.1 0.35 10.8 0.1 2.3 1 1 1 2 2 2 0 Metanogen output domain 1 DUF1031 PF06275.11 EST42953.1 - 0.041 14.1 0.2 0.099 12.9 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) DUF3974 PF13120.6 EST42953.1 - 0.14 12.3 2.4 0.2 11.8 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3974) DUF2680 PF10925.8 EST42953.1 - 0.22 11.6 0.0 0.22 11.6 0.0 3.6 4 1 0 4 4 4 0 Protein of unknown function (DUF2680) 6PF2K PF01591.18 EST42955.1 - 0.1 11.9 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Aa_trans PF01490.18 EST42956.1 - 1.8e-06 26.9 35.4 3.5e-06 26.0 35.4 1.4 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RecC_C PF17946.1 EST42957.1 - 0.05 13.4 0.1 0.076 12.8 0.1 1.2 1 0 0 1 1 1 0 RecC C-terminal domain DUF866 PF05907.13 EST42958.1 - 3.2e-19 69.4 0.0 3.5e-19 69.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) SoxD PF04267.12 EST42958.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Sarcosine oxidase, delta subunit family zinc_ribbon_4 PF13717.6 EST42958.1 - 0.2 11.6 2.8 8.2 6.4 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Elf1 PF05129.13 EST42958.1 - 0.23 11.5 2.8 4.9 7.3 0.2 2.4 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like DUF945 PF06097.11 EST42959.1 - 0.043 12.9 0.4 0.054 12.6 0.4 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) YedD PF13987.6 EST42961.1 - 0.0057 16.5 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 YedD-like protein UQ_con PF00179.26 EST42963.1 - 8.5e-45 151.8 0.0 1.7e-44 150.8 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EST42963.1 - 0.001 18.8 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EST42963.1 - 0.051 13.9 0.1 0.074 13.3 0.1 1.5 1 1 0 1 1 1 0 RWD domain LRR_8 PF13855.6 EST42964.1 - 9.8e-08 31.7 0.2 0.0016 18.2 0.0 2.5 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EST42964.1 - 0.0007 19.9 0.1 0.74 10.3 0.0 3.0 1 1 4 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EST42964.1 - 0.025 15.1 0.3 57 4.9 0.0 4.7 5 1 0 5 5 5 0 Leucine Rich Repeat LRRNT_2 PF08263.12 EST42964.1 - 0.027 14.8 7.1 0.059 13.7 7.1 1.6 1 1 0 1 1 1 0 Leucine rich repeat N-terminal domain GerPC PF10737.9 EST42965.1 - 0.094 12.8 6.7 0.17 11.9 6.7 1.3 1 0 0 1 1 1 0 Spore germination protein GerPC Enkurin PF13864.6 EST42965.1 - 0.25 11.8 1.4 0.52 10.8 1.4 1.5 1 0 0 1 1 1 0 Calmodulin-binding LRR_8 PF13855.6 EST42966.1 - 4.7e-08 32.7 0.1 0.0013 18.4 0.0 2.6 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EST42966.1 - 0.00046 20.5 0.1 0.63 10.5 0.0 3.0 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EST42966.1 - 0.017 15.6 0.3 49 5.0 0.0 4.7 5 1 0 5 5 5 0 Leucine Rich Repeat LRRNT_2 PF08263.12 EST42966.1 - 0.025 14.9 7.2 0.055 13.8 7.2 1.7 1 1 0 1 1 1 0 Leucine rich repeat N-terminal domain UQ_con PF00179.26 EST42968.1 - 1.1e-42 145.0 0.0 2.2e-42 144.0 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EST42968.1 - 0.0071 16.0 0.2 0.012 15.3 0.0 1.5 2 0 0 2 2 2 1 Prokaryotic E2 family B RWD PF05773.22 EST42968.1 - 0.044 14.1 0.0 0.055 13.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain DUF3530 PF12048.8 EST42971.1 - 0.046 13.1 0.0 0.046 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) VSP PF03302.13 EST42972.1 - 2.4e-05 23.4 91.7 0.00021 20.3 35.2 3.1 1 1 1 2 2 2 1 Giardia variant-specific surface protein DUF4366 PF14283.6 EST42972.1 - 0.33 11.0 0.0 0.33 11.0 0.0 3.0 2 1 2 4 4 4 0 Domain of unknown function (DUF4366) TPR_19 PF14559.6 EST42973.1 - 2.8e-16 59.8 16.5 1.8e-08 34.8 0.0 5.7 5 1 2 7 7 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 EST42973.1 - 2.7e-15 56.7 0.1 0.0019 18.8 0.0 5.2 4 0 0 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EST42973.1 - 7.1e-14 51.8 13.4 0.00013 22.2 1.2 4.6 4 0 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EST42973.1 - 7.8e-13 48.1 2.8 0.0034 18.1 0.0 6.2 5 1 1 6 6 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EST42973.1 - 8.8e-13 47.3 19.8 0.00017 21.4 0.0 7.4 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 EST42973.1 - 1.2e-08 34.4 5.7 0.056 13.5 0.2 6.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EST42973.1 - 1.5e-08 34.1 29.0 0.0022 17.7 0.1 7.2 8 1 1 9 9 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 EST42973.1 - 1.8e-08 33.9 14.2 0.00082 19.0 0.3 4.8 4 0 0 4 4 4 3 TPR repeat TPR_6 PF13174.6 EST42973.1 - 2e-08 34.3 11.2 2.8e-05 24.5 0.0 7.5 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 EST42973.1 - 7.3e-07 29.4 10.9 0.45 10.8 0.1 6.5 6 2 1 7 7 5 3 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EST42973.1 - 0.00016 21.7 9.0 0.11 12.5 0.0 4.1 3 1 0 4 4 4 2 Putative TPR-like repeat TPR_8 PF13181.6 EST42973.1 - 0.00017 21.5 15.9 0.23 11.8 0.1 6.5 7 0 0 7 7 6 2 Tetratricopeptide repeat PPR_2 PF13041.6 EST42973.1 - 0.0044 17.2 0.3 50 4.2 0.0 4.0 3 0 0 3 3 3 0 PPR repeat family BTAD PF03704.17 EST42973.1 - 0.006 17.0 0.5 12 6.3 0.1 3.7 4 1 0 4 4 4 0 Bacterial transcriptional activator domain TPR_9 PF13371.6 EST42973.1 - 0.012 15.8 0.9 3.8 7.7 0.1 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat ATP-synt_D PF01813.17 EST42973.1 - 0.016 15.0 0.5 0.045 13.6 0.5 1.7 1 0 0 1 1 1 0 ATP synthase subunit D PPR PF01535.20 EST42973.1 - 0.036 14.3 0.9 11 6.5 0.0 4.7 4 0 0 4 4 4 0 PPR repeat TPR_17 PF13431.6 EST42973.1 - 0.042 14.2 10.2 10 6.8 0.0 6.3 6 1 1 7 7 4 0 Tetratricopeptide repeat YfiO PF13525.6 EST42973.1 - 0.052 13.3 0.3 0.052 13.3 0.3 3.0 4 0 0 4 4 4 0 Outer membrane lipoprotein TPR_18 PF13512.6 EST42973.1 - 0.054 13.6 3.6 0.066 13.3 0.9 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 EST42973.1 - 0.076 13.1 2.5 14 5.9 0.2 3.7 3 0 0 3 3 2 0 MIT (microtubule interacting and transport) domain ATP13 PF12921.7 EST42973.1 - 0.13 12.2 1.0 6.9 6.6 0.1 3.2 3 0 0 3 3 3 0 Mitochondrial ATPase expression DUF573 PF04504.14 EST42973.1 - 0.17 12.5 2.3 0.66 10.7 0.8 2.7 2 0 0 2 2 2 0 Protein of unknown function, DUF573 Med4 PF10018.9 EST42973.1 - 0.26 10.9 5.3 0.66 9.6 5.3 1.7 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 ATG16 PF08614.11 EST42973.1 - 0.45 10.7 11.6 0.27 11.5 9.0 1.9 2 0 0 2 2 1 0 Autophagy protein 16 (ATG16) Spc24 PF08286.11 EST42973.1 - 1.7 9.0 6.4 0.25 11.6 1.0 2.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 E1_UFD PF09358.10 EST42973.1 - 1.8 9.3 7.8 4.3 8.1 0.2 3.6 4 0 0 4 4 2 0 Ubiquitin fold domain Hrs_helical PF12210.8 EST42973.1 - 4.1 8.0 9.0 0.31 11.6 0.7 2.9 3 0 0 3 3 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate TPR_3 PF07720.12 EST42973.1 - 6.9 6.8 20.3 4.7 7.3 0.2 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat VSP PF03302.13 EST42976.1 - 0.5 9.2 34.8 6.1 5.6 34.5 2.9 1 1 0 1 1 1 0 Giardia variant-specific surface protein VSP PF03302.13 EST42978.1 - 3.1e-12 46.1 199.4 2e-07 30.2 36.9 6.7 1 1 6 7 7 7 6 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST42978.1 - 0.004 17.3 21.6 0.004 17.3 21.6 7.7 1 1 5 6 6 6 3 Furin-like repeat, cysteine-rich VSP PF03302.13 EST42979.1 - 1.3e-10 40.8 137.1 0.01 14.7 36.9 6.2 1 1 4 5 5 5 4 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST42979.1 - 0.0073 16.5 22.7 0.0073 16.5 22.7 6.7 1 1 6 7 7 7 2 Furin-like repeat, cysteine-rich PARM PF17061.5 EST42979.1 - 0.14 12.3 0.3 0.14 12.3 0.3 2.0 2 0 0 2 2 2 0 PARM VSP PF03302.13 EST42980.1 - 9.9e-13 47.7 164.1 0.00029 19.8 16.6 7.1 1 1 5 6 6 6 5 Giardia variant-specific surface protein Podoplanin PF05808.11 EST42980.1 - 0.039 14.1 0.5 0.067 13.3 0.5 1.4 1 0 0 1 1 1 0 Podoplanin PARM PF17061.5 EST42980.1 - 1.4 9.0 4.9 2.1 8.4 4.9 1.2 1 0 0 1 1 1 0 PARM FERM_F1 PF18379.1 EST42982.1 - 0.013 15.5 0.2 0.019 15.0 0.2 1.2 1 0 0 1 1 1 0 FERM F1 ubiquitin-like domain FERM_F2 PF18377.1 EST42982.1 - 0.14 12.1 1.3 0.19 11.6 1.3 1.1 1 0 0 1 1 1 0 FERM F2 acyl-CoA binding protein-like domain TcpS PF17456.2 EST42983.1 - 0.13 12.3 0.1 0.13 12.3 0.1 1.0 1 0 0 1 1 1 0 Toxin-coregulated pilus protein S VSP PF03302.13 EST42985.1 - 6.5e-09 35.1 103.1 0.0014 17.6 28.8 4.3 1 1 2 3 3 3 3 Giardia variant-specific surface protein DUF2749 PF10907.8 EST42985.1 - 0.2 11.8 0.2 0.38 11.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) Podoplanin PF05808.11 EST42985.1 - 8.9 6.4 9.4 6.2 6.9 5.6 2.4 1 1 1 2 2 2 0 Podoplanin DUF485 PF04341.12 EST42987.1 - 0.021 14.8 0.2 0.021 14.8 0.2 3.5 2 1 0 3 3 3 0 Protein of unknown function, DUF485 PspB PF06667.12 EST42987.1 - 1.8 8.7 8.2 0.49 10.5 0.3 2.8 2 0 0 2 2 2 0 Phage shock protein B DUF4446 PF14584.6 EST42987.1 - 4.5 7.3 7.4 0.24 11.4 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) 7tm_1 PF00001.21 EST42987.1 - 7.4 5.8 12.0 0.17 11.2 2.8 2.1 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) INTS5_C PF14838.6 EST42989.1 - 0.027 13.1 1.1 0.042 12.5 1.1 1.3 1 1 0 1 1 1 0 Integrator complex subunit 5 C-terminus Peptidase_C12 PF01088.21 EST42990.1 - 2.5e-15 56.8 0.3 4.3e-15 56.0 0.3 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Cloacin_immun PF03513.14 EST42990.1 - 0.082 13.3 0.4 0.17 12.2 0.4 1.6 1 0 0 1 1 1 0 Cloacin immunity protein zf-B_box PF00643.24 EST42991.1 - 6.2e-12 45.5 30.9 4e-07 30.1 9.9 2.3 2 0 0 2 2 2 2 B-box zinc finger CEBP_ZZ PF16366.5 EST42991.1 - 0.041 14.1 22.3 0.1 12.9 9.9 2.3 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain CALCOCO1 PF07888.11 EST42992.1 - 0.0039 16.1 5.6 0.0048 15.8 5.6 1.0 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like GAS PF13851.6 EST42992.1 - 0.01 15.2 6.9 0.012 15.0 6.9 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Mer2 PF09074.10 EST42992.1 - 0.013 15.3 4.6 0.016 15.0 4.6 1.0 1 0 0 1 1 1 0 Mer2 Spc7 PF08317.11 EST42992.1 - 0.014 14.3 6.2 0.015 14.2 6.2 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein KELK PF15796.5 EST42992.1 - 0.033 14.7 7.7 0.44 11.0 5.5 2.0 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase BST2 PF16716.5 EST42992.1 - 0.041 14.5 2.0 0.058 14.0 1.1 1.6 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Fez1 PF06818.15 EST42992.1 - 0.049 14.1 5.9 0.67 10.4 1.2 2.0 1 1 1 2 2 2 0 Fez1 Spectrin PF00435.21 EST42992.1 - 0.061 13.8 3.6 0.089 13.3 3.6 1.3 1 0 0 1 1 1 0 Spectrin repeat ATG16 PF08614.11 EST42992.1 - 0.064 13.5 5.3 0.076 13.2 3.7 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) HIP1_clath_bdg PF16515.5 EST42992.1 - 0.079 13.6 5.0 0.1 13.3 5.0 1.2 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 PI3K_P85_iSH2 PF16454.5 EST42992.1 - 0.097 12.3 6.9 0.071 12.7 1.8 2.0 1 1 2 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain ADIP PF11559.8 EST42992.1 - 0.1 12.7 7.5 0.12 12.5 7.5 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Tup_N PF08581.10 EST42992.1 - 0.14 12.5 6.5 3.9 7.8 1.1 2.7 1 1 2 3 3 3 0 Tup N-terminal DivIC PF04977.15 EST42992.1 - 0.28 11.0 7.9 0.57 10.0 1.8 2.1 1 1 1 2 2 2 0 Septum formation initiator JIP_LZII PF16471.5 EST42992.1 - 0.28 11.4 5.7 0.13 12.4 2.8 1.9 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II SlyX PF04102.12 EST42992.1 - 0.42 11.3 3.9 1 10.0 0.8 2.3 1 1 1 2 2 2 0 SlyX FAM76 PF16046.5 EST42992.1 - 2.2 7.6 5.9 2.2 7.5 5.9 1.0 1 0 0 1 1 1 0 FAM76 protein KH_6 PF15985.5 EST42993.1 - 0.00053 20.3 0.6 0.0015 18.9 0.3 1.8 2 0 0 2 2 2 1 KH domain zf-C3HC4_3 PF13920.6 EST42994.1 - 1.5e-10 40.8 9.7 3.2e-10 39.7 9.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EST42994.1 - 2.2e-05 24.3 9.7 2.2e-05 24.3 9.7 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 EST42994.1 - 0.00016 21.9 12.0 0.00016 21.9 12.0 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EST42994.1 - 0.00019 21.2 12.4 0.00019 21.2 12.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EST42994.1 - 0.00019 21.2 11.5 0.00026 20.8 10.3 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EST42994.1 - 0.00024 20.9 12.3 0.00065 19.5 12.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EST42994.1 - 0.0019 18.2 5.3 0.0019 18.2 5.3 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EST42994.1 - 0.006 16.7 8.5 0.058 13.6 8.9 2.3 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EST42994.1 - 0.57 10.0 8.7 1.7 8.5 8.6 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain UBA_4 PF14555.6 EST42995.1 - 1.7e-06 27.7 1.4 3.3e-06 26.8 0.2 1.9 2 0 0 2 2 2 1 UBA-like domain DUF4238 PF14022.6 EST42995.1 - 0.018 14.6 0.2 0.018 14.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) Trigger_C PF05698.14 EST42995.1 - 0.02 14.9 2.7 0.026 14.6 2.7 1.3 1 1 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus Flg_bb_rod PF00460.20 EST42995.1 - 0.12 12.3 0.2 0.22 11.5 0.2 1.4 1 0 0 1 1 1 0 Flagella basal body rod protein RRM_1 PF00076.22 EST42996.1 - 5.7e-06 26.1 0.2 9.6e-05 22.1 0.0 2.6 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SWIB PF02201.18 EST42996.1 - 2.2 8.3 5.6 1.9 8.4 1.0 2.7 2 1 0 2 2 2 0 SWIB/MDM2 domain Methyltransf_31 PF13847.6 EST42997.1 - 1.5e-09 37.9 0.0 1.8e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EST42997.1 - 6.8e-07 29.9 0.0 1.1e-06 29.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EST42997.1 - 1.6e-06 28.6 0.0 2.3e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EST42997.1 - 0.0032 18.2 0.0 0.0045 17.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 EST42997.1 - 0.12 11.9 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Spc7 PF08317.11 EST42998.1 - 1.4 7.7 37.4 0.097 11.5 5.2 3.3 2 1 1 3 3 3 0 Spc7 kinetochore protein ComC PF03047.14 EST42998.1 - 1.8 8.4 4.9 0.89 9.4 0.1 3.1 4 0 0 4 4 4 0 COMC family Ebp2 PF05890.12 EST42999.1 - 1e-07 31.8 29.0 1.2e-07 31.6 29.0 1.0 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 DUF2001 PF09393.10 EST42999.1 - 1.8 8.5 8.3 0.23 11.4 3.5 1.9 3 0 0 3 3 3 0 Phage tail tube protein UDPGP PF01704.18 EST43000.1 - 2.8e-135 451.2 3.7 3.4e-135 450.9 3.7 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase UQ_con PF00179.26 EST43003.1 - 1.6e-23 82.9 0.9 2e-23 82.6 0.9 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EST43003.1 - 0.1 12.9 0.4 0.14 12.5 0.4 1.3 1 0 0 1 1 1 0 RWD domain RNB PF00773.19 EST43004.1 - 3.1e-77 260.1 1.7 4.1e-77 259.7 0.1 1.9 2 0 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 EST43004.1 - 3.9e-05 23.6 0.2 8.9e-05 22.4 0.2 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PP2C PF00481.21 EST43005.1 - 4.7e-25 88.7 0.6 1.7e-24 86.9 0.1 1.9 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 EST43005.1 - 1.3e-08 34.8 0.0 2.4e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C DNA_pol_B PF00136.21 EST43009.1 - 5.4e-128 427.6 7.3 7.5e-128 427.1 7.3 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EST43009.1 - 2.8e-62 210.8 6.2 2.8e-62 210.8 6.2 1.9 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EST43009.1 - 4.6e-05 23.8 12.0 4.6e-05 23.8 12.0 2.5 2 1 1 3 3 3 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.9 EST43009.1 - 0.00038 20.2 0.1 0.0011 18.7 0.1 1.8 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Peptidase_C12 PF01088.21 EST43010.1 - 1.7e-15 57.3 0.2 3.4e-15 56.4 0.2 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Cloacin_immun PF03513.14 EST43010.1 - 0.081 13.3 0.5 0.16 12.4 0.5 1.4 1 0 0 1 1 1 0 Cloacin immunity protein WD40_like PF17005.5 EST43013.1 - 0.014 14.7 0.1 0.014 14.7 0.1 1.5 2 0 0 2 2 2 0 WD40-like domain SMP_LBD PF17047.5 EST43014.1 - 0.017 14.6 1.8 0.051 13.1 0.1 2.2 2 0 0 2 2 2 0 Synaptotagmin-like mitochondrial-lipid-binding domain DUF2870 PF11069.8 EST43015.1 - 1.9e-06 28.2 0.0 4.9e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) Histone PF00125.24 EST43016.1 - 2e-40 138.2 5.6 2.3e-40 138.0 5.6 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EST43016.1 - 2.2e-05 24.7 0.0 5.1e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EST43016.1 - 7.2e-05 22.9 1.7 0.00015 21.9 0.1 2.1 1 1 1 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EST43016.1 - 0.00086 19.9 0.9 0.00086 19.9 0.9 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain TFIID-31kDa PF02291.15 EST43016.1 - 0.078 13.0 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit ubiquitin PF00240.23 EST43017.1 - 0.012 15.3 0.6 0.024 14.4 0.6 1.5 1 0 0 1 1 1 0 Ubiquitin family CorC_HlyC PF03471.17 EST43017.1 - 0.071 13.1 0.0 0.2 11.7 0.0 1.7 2 0 0 2 2 2 0 Transporter associated domain Ank_2 PF12796.7 EST43018.1 - 8e-14 52.0 0.0 1.9e-07 31.5 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EST43018.1 - 1.9e-06 27.8 0.0 0.29 11.8 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 EST43018.1 - 8.7e-05 23.0 0.0 0.04 14.5 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 EST43018.1 - 0.011 16.2 0.0 0.24 11.9 0.0 2.6 3 0 0 3 3 3 0 Ankyrin repeat Ank_5 PF13857.6 EST43018.1 - 0.038 14.3 0.0 0.62 10.5 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Epimerase PF01370.21 EST43019.1 - 2.7e-48 164.5 0.0 3.6e-48 164.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EST43019.1 - 4.8e-40 138.0 0.0 9e-39 133.8 0.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EST43019.1 - 1.3e-13 50.6 0.1 3.7e-13 49.1 0.1 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EST43019.1 - 1.7e-11 43.8 0.1 2.3e-10 40.1 0.1 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EST43019.1 - 1.7e-07 30.6 0.1 5.3e-07 29.0 0.1 1.5 1 1 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EST43019.1 - 5.8e-05 22.4 0.2 0.012 14.8 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.25 EST43019.1 - 0.0046 16.4 0.1 0.008 15.6 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase ThiF PF00899.21 EST43019.1 - 0.026 13.9 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 ThiF family NmrA PF05368.13 EST43019.1 - 0.054 13.0 0.1 0.078 12.5 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family Pyr_redox PF00070.27 EST43019.1 - 0.057 14.0 0.0 0.12 13.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EST43019.1 - 0.061 13.2 0.0 0.096 12.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SlyX PF04102.12 EST43020.1 - 2.3 8.9 5.6 0.58 10.8 1.3 2.2 1 1 1 2 2 2 0 SlyX SET PF00856.28 EST43021.1 - 0.026 14.9 0.1 0.34 11.3 0.0 2.4 2 0 0 2 2 2 0 SET domain Epimerase PF01370.21 EST43022.1 - 2.7e-48 164.5 0.0 3.6e-48 164.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EST43022.1 - 4.8e-40 138.0 0.0 9e-39 133.8 0.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EST43022.1 - 1.3e-13 50.6 0.1 3.7e-13 49.1 0.1 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EST43022.1 - 1.7e-11 43.8 0.1 2.3e-10 40.1 0.1 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EST43022.1 - 1.7e-07 30.6 0.1 5.3e-07 29.0 0.1 1.5 1 1 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EST43022.1 - 5.8e-05 22.4 0.2 0.012 14.8 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.25 EST43022.1 - 0.0046 16.4 0.1 0.008 15.6 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase ThiF PF00899.21 EST43022.1 - 0.026 13.9 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 ThiF family NmrA PF05368.13 EST43022.1 - 0.054 13.0 0.1 0.078 12.5 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family Pyr_redox PF00070.27 EST43022.1 - 0.057 14.0 0.0 0.12 13.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EST43022.1 - 0.061 13.2 0.0 0.096 12.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SPATA1_C PF15743.5 EST43023.1 - 0.036 14.2 0.8 0.036 14.2 0.8 1.9 2 0 0 2 2 2 0 Spermatogenesis-associated C-terminus AP1AR PF15745.5 EST43023.1 - 0.045 13.4 0.1 0.082 12.5 0.1 1.4 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein Ribonuclease_T2 PF00445.18 EST43023.1 - 0.079 13.2 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease T2 family Nup35_RRM PF05172.13 EST43023.1 - 0.088 12.8 0.0 0.27 11.2 0.0 1.8 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Kinesin PF00225.23 EST43025.1 - 4.6e-88 295.3 6.2 4.6e-88 295.3 6.2 2.1 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EST43025.1 - 7.1e-33 113.6 0.5 7.1e-33 113.6 0.5 2.2 2 1 1 3 3 3 1 Microtubule binding HALZ PF02183.18 EST43025.1 - 2e-05 24.7 9.8 0.0084 16.3 1.1 3.7 2 1 1 3 3 3 2 Homeobox associated leucine zipper THOC7 PF05615.13 EST43025.1 - 0.00046 20.5 7.3 0.00046 20.5 7.3 2.4 1 1 1 2 2 2 1 Tho complex subunit 7 TMF_DNA_bd PF12329.8 EST43025.1 - 0.0006 19.8 1.3 0.0006 19.8 1.3 3.5 1 1 2 3 3 3 1 TATA element modulatory factor 1 DNA binding Ribosomal_L50 PF10501.9 EST43025.1 - 0.0016 18.6 1.9 0.0079 16.3 1.4 2.5 1 1 0 1 1 1 1 Ribosomal subunit 39S ATG16 PF08614.11 EST43025.1 - 0.13 12.5 22.8 0.41 10.8 22.1 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 EST43025.1 - 0.26 10.6 15.0 0.52 9.6 15.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Troponin PF00992.20 EST43025.1 - 0.44 10.8 11.3 0.041 14.2 3.7 2.8 1 1 1 2 2 2 0 Troponin APG6_N PF17675.1 EST43025.1 - 0.93 10.0 19.9 2.9 8.4 16.7 2.8 2 1 0 2 2 1 0 Apg6 coiled-coil region YabA PF06156.13 EST43025.1 - 1.3 9.7 15.4 3.3 8.4 2.6 3.7 1 1 2 3 3 3 0 Initiation control protein YabA Myb_DNA-bind_3 PF12776.7 EST43025.1 - 2 9.5 5.3 1.7 9.7 2.7 2.4 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DivIC PF04977.15 EST43025.1 - 2.3 8.0 22.3 0.69 9.7 2.0 4.0 1 1 3 4 4 4 0 Septum formation initiator ZapB PF06005.12 EST43025.1 - 3.9 8.0 14.1 0.36 11.3 2.9 3.1 1 1 1 2 2 2 0 Cell division protein ZapB bZIP_1 PF00170.21 EST43025.1 - 4 7.6 8.7 13 6.0 0.3 3.6 2 1 1 3 3 3 0 bZIP transcription factor DUF2203 PF09969.9 EST43025.1 - 7.3 7.3 12.3 10 6.9 2.5 2.9 2 1 1 3 3 2 0 Uncharacterized conserved protein (DUF2203) Occludin_ELL PF07303.13 EST43025.1 - 7.3 7.4 12.2 6.2 7.6 2.1 3.5 1 1 2 3 3 3 0 Occludin homology domain Laminin_II PF06009.12 EST43025.1 - 7.8 6.5 18.8 10 6.1 3.7 2.9 1 1 2 3 3 3 0 Laminin Domain II DUF1664 PF07889.12 EST43025.1 - 9.8 6.2 15.0 0.71 9.9 1.3 2.9 2 1 2 4 4 3 0 Protein of unknown function (DUF1664) DUF4327 PF14217.6 EST43026.1 - 0.043 14.0 0.2 3.1 8.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4327) RNA_pol_A_bac PF01000.26 EST43026.1 - 0.16 12.4 1.6 0.93 9.9 0.9 2.3 2 1 0 2 2 2 0 RNA polymerase Rpb3/RpoA insert domain AMP-binding PF00501.28 EST43027.1 - 3.8e-64 216.9 0.0 1.1e-63 215.3 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme DUF5336 PF17270.2 EST43028.1 - 0.43 10.2 4.6 1.2 8.7 4.6 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5336) Histone PF00125.24 EST43030.1 - 2e-40 138.2 5.6 2.3e-40 138.0 5.6 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EST43030.1 - 2.2e-05 24.7 0.0 5.1e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EST43030.1 - 7.2e-05 22.9 1.7 0.00015 21.9 0.1 2.1 1 1 1 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EST43030.1 - 0.00086 19.9 0.9 0.00086 19.9 0.9 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain TFIID-31kDa PF02291.15 EST43030.1 - 0.078 13.0 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit PMSR PF01625.21 EST43031.1 - 8.8e-31 107.2 3.2 1.1e-30 106.9 3.2 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase TPR_MLP1_2 PF07926.12 EST43032.1 - 0.88 9.6 23.6 0.34 11.0 14.0 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF724 PF05266.14 EST43032.1 - 4.4 7.1 23.2 0.094 12.5 5.9 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF724) KELK PF15796.5 EST43032.1 - 7.3 7.1 15.8 0.52 10.8 2.0 3.3 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase P22_AR_N PF10547.9 EST43035.1 - 0.017 15.5 1.4 0.041 14.2 0.4 2.1 2 0 0 2 2 2 0 P22_AR N-terminal domain Orthopox_A43R PF06517.11 EST43035.1 - 0.029 14.2 0.5 0.2 11.4 0.0 2.2 2 0 0 2 2 2 0 Orthopoxvirus A43R protein Rep_Org_C PF06926.11 EST43035.1 - 0.045 14.1 1.6 0.087 13.1 0.4 2.1 2 0 0 2 2 2 0 Putative replisome organiser protein C-terminus TPR_19 PF14559.6 EST43035.1 - 0.11 13.0 0.0 0.21 12.1 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat GAS PF13851.6 EST43036.1 - 3.1e-56 189.9 28.0 3.1e-56 189.9 28.0 3.4 1 1 2 3 3 3 1 Growth-arrest specific micro-tubule binding GCP_C_terminal PF04130.13 EST43037.1 - 8.1e-22 78.1 12.0 8.1e-22 78.1 12.0 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal Histone PF00125.24 EST43038.1 - 2e-40 138.2 5.6 2.3e-40 138.0 5.6 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EST43038.1 - 2.2e-05 24.7 0.0 5.1e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EST43038.1 - 7.2e-05 22.9 1.7 0.00015 21.9 0.1 2.1 1 1 1 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EST43038.1 - 0.00086 19.9 0.9 0.00086 19.9 0.9 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain TFIID-31kDa PF02291.15 EST43038.1 - 0.078 13.0 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit AMP-binding PF00501.28 EST43039.1 - 2.5e-68 230.6 0.0 7.1e-68 229.1 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme Hexapep PF00132.24 EST43040.1 - 0.00011 21.8 8.2 0.024 14.3 0.3 3.0 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) LRR_4 PF12799.7 EST43041.1 - 9.2e-08 32.3 30.0 0.0038 17.6 0.5 5.2 3 2 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EST43041.1 - 2.2e-05 24.1 22.1 0.0018 18.0 1.8 4.2 2 2 1 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 EST43041.1 - 0.007 16.3 12.9 9 6.6 0.0 5.2 5 0 0 5 5 5 3 Leucine Rich repeat MU117 PF15474.6 EST43041.1 - 0.033 15.0 1.8 0.075 13.8 1.8 1.6 1 0 0 1 1 1 0 Meiotically up-regulated gene family Peptidase_C47 PF05543.13 EST43041.1 - 0.095 12.3 3.2 0.3 10.6 0.3 2.3 2 0 0 2 2 2 0 Staphopain peptidase C47 MRP-S23 PF10484.9 EST43041.1 - 1.3 9.2 7.2 0.76 10.0 2.0 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal protein S23 Sec20 PF03908.13 EST43041.1 - 2.4 8.1 8.1 0.68 9.9 0.6 3.1 1 1 2 3 3 3 0 Sec20 LRR_1 PF00560.33 EST43041.1 - 5.4 8.0 15.3 1.6e+02 3.5 0.4 5.2 2 2 1 3 3 3 0 Leucine Rich Repeat Histone PF00125.24 EST43042.1 - 1.8e-39 135.1 5.6 1.8e-39 135.1 5.6 1.5 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EST43042.1 - 7.5e-05 23.0 0.0 0.0002 21.7 0.0 1.7 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EST43042.1 - 0.00058 19.9 2.8 0.00064 19.8 0.1 2.4 2 1 1 3 3 3 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EST43042.1 - 0.0063 17.1 2.2 0.012 16.2 2.2 1.5 1 0 0 1 1 1 1 PCNA-associated factor histone like domain bZIP_2 PF07716.15 EST43045.1 - 0.018 15.1 1.7 0.018 15.1 1.7 2.9 3 0 0 3 3 3 0 Basic region leucine zipper MCC-bdg_PDZ PF10506.9 EST43045.1 - 0.04 13.9 5.4 5.2 7.2 0.3 3.6 3 0 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Pico_P2A PF00947.19 EST43045.1 - 0.15 12.1 0.2 0.39 10.8 0.0 1.7 1 1 1 2 2 2 0 Picornavirus core protein 2A DUF3287 PF11690.8 EST43045.1 - 0.54 10.0 4.7 0.88 9.3 2.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) MscS_porin PF12795.7 EST43045.1 - 2.1 7.9 20.1 1.5 8.3 5.1 2.1 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain CCDC92 PF14916.6 EST43045.1 - 2.2 8.1 13.2 0.31 10.8 2.6 3.1 3 1 0 3 3 3 0 Coiled-coil domain of unknown function Annexin PF00191.20 EST43046.1 - 1.5e-32 111.4 7.2 2.6e-14 53.0 0.2 4.2 4 0 0 4 4 4 4 Annexin SAM_Exu PF18609.1 EST43046.1 - 0.028 14.5 0.1 0.43 10.7 0.0 2.8 2 0 0 2 2 2 0 Exuperantia SAM-like domain BBP1_C PF15272.6 EST43047.1 - 0.00047 20.0 2.9 0.00047 20.0 2.9 1.6 1 1 1 2 2 2 1 Spindle pole body component BBP1, C-terminal TPR_MLP1_2 PF07926.12 EST43047.1 - 0.0023 18.0 6.2 0.005 16.9 6.2 1.5 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein CALCOCO1 PF07888.11 EST43047.1 - 0.0045 15.9 4.4 0.0057 15.6 4.0 1.3 1 1 1 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4472 PF14739.6 EST43047.1 - 0.0069 17.1 7.0 0.012 16.3 3.8 2.4 1 1 0 2 2 2 1 Domain of unknown function (DUF4472) KIP1 PF07765.12 EST43047.1 - 0.048 13.8 0.4 0.13 12.4 0.3 1.8 1 1 0 1 1 1 0 KIP1-like protein DivIC PF04977.15 EST43047.1 - 0.067 13.0 7.5 0.21 11.4 1.0 2.7 1 1 1 2 2 2 0 Septum formation initiator Cnn_1N PF07989.11 EST43047.1 - 0.072 13.3 5.4 0.052 13.7 2.8 1.9 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 DHR10 PF18595.1 EST43047.1 - 0.093 12.8 6.5 1.3 9.1 2.9 2.4 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain Cob_adeno_trans PF01923.18 EST43047.1 - 0.1 12.7 2.3 0.1 12.7 1.0 1.6 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Jnk-SapK_ap_N PF09744.9 EST43047.1 - 0.28 11.4 8.4 0.13 12.4 6.1 1.5 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Uso1_p115_C PF04871.13 EST43047.1 - 0.86 10.0 4.7 1.8 9.0 4.5 1.9 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Vps39_2 PF10367.9 EST43050.1 - 0.00084 19.8 1.7 0.0041 17.6 1.7 2.3 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Sgf11 PF08209.11 EST43050.1 - 0.15 11.6 0.1 0.35 10.5 0.1 1.5 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) Adhes-Ig_like PF09085.10 EST43051.1 - 0.04 14.0 0.1 0.042 14.0 0.1 1.1 1 0 0 1 1 1 0 Adhesion molecule, immunoglobulin-like DUF1892 PF08987.10 EST43054.1 - 0.033 14.4 0.0 0.068 13.4 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1892) Glyco_hydro2_C5 PF18565.1 EST43054.1 - 0.065 13.1 0.6 4.5 7.2 0.0 2.9 2 2 1 3 3 3 0 Glycoside hydrolase family 2 C-terminal domain 5 Cue1_U7BR PF18499.1 EST43055.1 - 0.04 14.0 0.4 0.057 13.5 0.4 1.4 1 0 0 1 1 1 0 Ubc7p-binding region of Cue1 SIR2 PF02146.17 EST43056.1 - 2.3e-21 76.5 2.4 2.9e-20 72.9 0.8 3.1 2 1 0 2 2 2 1 Sir2 family LicD PF04991.13 EST43057.1 - 0.2 11.8 6.6 0.28 11.3 6.6 1.3 1 0 0 1 1 1 0 LicD family Paralemmin PF03285.15 EST43057.1 - 0.24 10.9 6.1 0.3 10.6 6.1 1.1 1 0 0 1 1 1 0 Paralemmin TSC22 PF01166.18 EST43058.1 - 0.026 14.8 0.3 0.026 14.8 0.3 5.2 5 2 0 5 5 5 0 TSC-22/dip/bun family HalX PF08663.10 EST43058.1 - 0.03 14.7 2.8 0.03 14.7 2.8 4.0 2 1 2 4 4 4 0 HalX domain FlaC_arch PF05377.11 EST43058.1 - 1.2 9.6 11.9 13 6.3 0.4 5.2 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) DUF5320 PF17253.2 EST43058.1 - 5 8.2 7.9 72 4.5 0.3 3.7 2 2 0 2 2 2 0 Family of unknown function (DUF5320) Pribosyltran PF00156.27 EST43060.1 - 1e-07 31.6 0.0 1.4e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EST43060.1 - 3.4e-05 23.4 0.0 4.8e-05 22.9 0.0 1.3 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase WD40 PF00400.32 EST43061.1 - 7.8e-06 26.5 0.8 0.0077 17.1 0.1 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat Ubie_methyltran PF01209.18 EST43061.1 - 0.016 14.6 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family TMEM40 PF15817.5 EST43062.1 - 0.12 12.1 0.1 0.17 11.7 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 40 family DUF2428 PF10350.9 EST43063.1 - 0.02 14.1 0.1 0.042 13.1 0.0 1.5 2 0 0 2 2 2 0 Putative death-receptor fusion protein (DUF2428) RRM_1 PF00076.22 EST43065.1 - 8.2e-05 22.4 0.1 0.00015 21.6 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EST43065.1 - 0.029 14.5 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif zf-RING_6 PF14835.6 EST43066.1 - 0.098 12.5 0.4 0.21 11.5 0.4 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein LRR_8 PF13855.6 EST43067.1 - 6.7e-07 29.0 0.0 0.0065 16.2 0.0 2.4 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EST43067.1 - 0.0012 19.2 0.1 0.39 11.2 0.0 3.0 1 1 2 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EST43067.1 - 0.0083 16.5 0.2 74 4.5 0.0 5.0 4 2 0 4 4 4 0 Leucine Rich Repeat LRRNT_2 PF08263.12 EST43067.1 - 0.01 16.1 5.2 0.023 15.0 5.2 1.7 1 1 0 1 1 1 0 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 EST43067.1 - 0.042 13.9 2.4 0.98 9.6 0.2 3.5 4 0 0 4 4 4 0 Leucine Rich repeat Trefoil PF00088.18 EST43069.1 - 0.0076 16.1 0.8 0.014 15.3 0.3 1.6 2 0 0 2 2 2 1 Trefoil (P-type) domain DUF760 PF05542.11 EST43073.1 - 0.082 13.3 0.6 0.15 12.5 0.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF760) Myb_DNA-binding PF00249.31 EST43073.1 - 0.093 12.9 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST43073.1 - 0.52 10.6 4.6 0.31 11.3 0.4 2.7 3 0 0 3 3 3 0 Myb-like DNA-binding domain MBD PF01429.19 EST43074.1 - 0.09 12.5 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 Methyl-CpG binding domain Fer4 PF00037.27 EST43076.1 - 8.4e-08 31.7 8.1 1.4e-05 24.6 0.9 2.4 2 1 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 EST43076.1 - 6.1e-07 29.5 5.7 7.1e-07 29.3 5.7 1.1 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 EST43076.1 - 1.4e-05 25.2 8.9 0.028 14.9 3.0 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EST43076.1 - 1.9e-05 25.1 6.8 4.7e-05 23.9 7.2 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 EST43076.1 - 5.3e-05 23.1 7.0 0.0052 16.8 1.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 EST43076.1 - 6.9e-05 22.9 9.0 0.00046 20.2 9.2 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 EST43076.1 - 0.0007 20.5 4.3 0.034 15.1 0.7 2.1 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 EST43076.1 - 0.0017 18.4 7.7 0.11 12.6 3.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_3 PF12798.7 EST43076.1 - 0.0023 18.8 9.5 0.076 14.0 3.5 2.4 2 1 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 EST43076.1 - 0.016 15.3 9.6 0.035 14.2 9.6 1.6 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 EST43076.1 - 0.03 14.8 5.3 0.26 11.8 0.8 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain PHP PF02811.19 EST43076.1 - 0.048 14.0 0.0 0.048 14.0 0.0 1.1 1 0 0 1 1 1 0 PHP domain Fer4_17 PF13534.6 EST43076.1 - 1.7 9.2 9.8 1.3e+02 3.3 9.8 2.1 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 EST43076.1 - 1.9 9.3 8.7 0.43 11.4 3.0 2.0 1 1 1 2 2 2 0 4Fe-4S single cluster domain Colicin_immun PF09204.10 EST43079.1 - 0.02 15.4 0.5 0.041 14.4 0.1 1.6 2 0 0 2 2 2 0 Bacterial self-protective colicin-like immunity Fe_hyd_lg_C PF02906.14 EST43080.1 - 4.8e-70 236.0 0.9 6.9e-70 235.5 0.9 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fer4_7 PF12838.7 EST43080.1 - 2e-08 34.7 24.4 5.6e-06 26.9 13.8 2.8 2 1 2 4 4 4 3 4Fe-4S dicluster domain Fer4 PF00037.27 EST43080.1 - 3.6e-08 32.9 23.3 4.6e-06 26.2 4.9 3.3 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_21 PF14697.6 EST43080.1 - 1.4e-07 31.5 8.9 1.4e-07 31.5 8.9 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 EST43080.1 - 1.6e-07 31.4 8.3 1.6e-07 31.4 8.3 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 EST43080.1 - 3.1e-07 30.8 6.6 3.1e-07 30.8 6.6 2.0 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EST43080.1 - 5.2e-07 30.0 6.9 1.7e-06 28.4 6.9 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 EST43080.1 - 6.3e-07 29.1 13.9 0.0022 18.0 4.5 3.0 2 0 0 2 2 2 2 4Fe-4S binding domain Fe_hyd_SSU PF02256.17 EST43080.1 - 1.1e-06 28.6 0.5 3.1e-06 27.1 0.4 1.8 2 0 0 2 2 1 1 Iron hydrogenase small subunit Fer4_10 PF13237.6 EST43080.1 - 4.4e-06 26.7 23.8 8.5e-05 22.6 13.7 3.1 2 1 2 4 4 4 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 EST43080.1 - 4.5e-06 26.5 18.2 0.0016 18.5 5.5 3.0 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_4 PF12800.7 EST43080.1 - 0.00041 20.6 1.3 0.00041 20.6 1.3 3.2 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 EST43080.1 - 0.0012 19.8 23.8 0.0044 17.9 1.9 3.3 2 1 2 4 4 4 2 4Fe-4S double cluster binding domain Fer4_18 PF13746.6 EST43080.1 - 0.0027 17.9 5.0 0.15 12.3 0.2 2.8 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_3 PF12798.7 EST43080.1 - 0.0068 17.3 7.1 0.0068 17.3 7.1 3.4 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_13 PF13370.6 EST43080.1 - 0.01 16.3 10.9 0.13 12.8 0.6 2.8 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 EST43080.1 - 0.013 16.3 13.0 0.16 12.7 0.6 3.3 3 0 0 3 3 2 0 4Fe-4S single cluster domain Fer4_22 PF17179.4 EST43080.1 - 0.019 15.8 9.5 0.56 11.1 1.4 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_20 PF14691.6 EST43080.1 - 2.7 7.8 8.6 3.2 7.6 0.3 2.5 2 1 1 3 3 3 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Adeno_E4_ORF3 PF06931.11 EST43081.1 - 0.0019 18.4 0.0 0.0054 16.9 0.0 1.7 1 0 0 1 1 1 1 Mastadenovirus E4 ORF3 protein NUDIX PF00293.28 EST43082.1 - 0.0023 17.9 0.0 0.003 17.6 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Proteasome PF00227.26 EST43083.1 - 6.5e-30 104.0 0.7 8.4e-30 103.7 0.7 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EST43083.1 - 2.8e-10 39.7 0.0 5.3e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3947 PF13135.6 EST43083.1 - 0.39 10.9 2.2 0.38 11.0 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3947) zf-C3H2C3 PF17122.5 EST43085.1 - 0.00066 19.7 9.5 0.0021 18.0 9.5 1.9 1 0 0 1 1 1 1 Zinc-finger Prok-RING_1 PF14446.6 EST43085.1 - 0.18 11.7 6.5 0.45 10.5 6.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Vps39_2 PF10367.9 EST43085.1 - 0.42 11.1 6.9 0.41 11.1 3.8 2.5 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-C3HC4_2 PF13923.6 EST43085.1 - 0.55 10.1 11.2 1.5 8.7 11.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EST43085.1 - 1.2 9.3 7.2 3.5 7.7 7.2 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 EST43085.1 - 5 7.1 9.7 18 5.3 9.7 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TFIIB PF00382.19 EST43086.1 - 0.00047 20.1 0.1 0.002 18.2 0.0 2.1 2 0 0 2 2 2 1 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 EST43086.1 - 0.0013 18.2 0.7 0.0026 17.3 0.7 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding TRPM_tetra PF16519.5 EST43086.1 - 0.16 12.1 1.3 0.91 9.7 0.1 2.5 2 0 0 2 2 2 0 Tetramerisation domain of TRPM EF-hand_7 PF13499.6 EST43087.1 - 1.3e-10 41.5 2.4 4.8e-07 30.1 1.6 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EST43087.1 - 1.3e-09 36.9 2.9 0.00038 19.8 0.2 4.0 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 EST43087.1 - 4.6e-08 32.4 0.6 0.0015 18.3 0.1 3.9 3 1 1 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 EST43087.1 - 3.1e-07 29.6 1.2 0.095 12.2 0.1 3.6 3 1 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EST43087.1 - 3.5e-05 23.6 1.3 0.23 11.4 0.0 3.0 2 1 1 3 3 3 2 EF-hand domain pair ASFV_J13L PF05568.11 EST43087.1 - 0.046 13.5 0.3 0.082 12.7 0.3 1.5 1 1 0 1 1 1 0 African swine fever virus J13L protein TTL PF03133.15 EST43088.1 - 7.3e-49 166.5 1.0 1e-48 166.0 1.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EST43088.1 - 3.4e-08 33.0 1.9 0.0022 17.3 0.0 3.2 2 1 1 3 3 3 3 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EST43088.1 - 0.00013 21.3 0.0 0.0017 17.7 0.0 2.1 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 EST43088.1 - 0.017 15.2 0.0 7.5 6.6 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp domain RimK PF08443.11 EST43088.1 - 0.15 11.6 0.0 7.9 6.0 0.0 2.3 2 0 0 2 2 2 0 RimK-like ATP-grasp domain SPACA9 PF15120.6 EST43089.1 - 0.0032 17.3 5.9 0.0046 16.8 5.9 1.2 1 0 0 1 1 1 1 Sperm acrosome-associated protein 9 Baculo_PEP_C PF04513.12 EST43089.1 - 0.053 13.6 4.4 0.11 12.6 4.3 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3142 PF11340.8 EST43089.1 - 0.054 13.3 0.4 0.089 12.6 0.2 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3142) LMBR1 PF04791.16 EST43089.1 - 0.13 11.1 2.4 0.15 11.0 2.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Laminin_II PF06009.12 EST43089.1 - 0.16 12.0 6.2 0.25 11.3 5.9 1.5 1 1 0 1 1 1 0 Laminin Domain II Spectrin PF00435.21 EST43089.1 - 0.36 11.3 8.3 1 9.9 7.0 2.2 1 1 1 2 2 2 0 Spectrin repeat DUF2274 PF10038.9 EST43089.1 - 0.38 11.2 3.1 12 6.5 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2274) MutS_III PF05192.18 EST43089.1 - 1.5 9.0 4.1 5 7.3 0.1 2.0 1 1 1 2 2 2 0 MutS domain III DUF948 PF06103.11 EST43089.1 - 1.9 8.8 7.7 1.8 8.9 1.9 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) ABC_tran_CTD PF16326.5 EST43089.1 - 8.8 6.7 10.2 18 5.6 4.9 2.8 1 1 1 2 2 2 0 ABC transporter C-terminal domain Aminotran_1_2 PF00155.21 EST43090.1 - 4.5e-23 82.0 0.1 5.8e-23 81.7 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II CTP_transf_1 PF01148.20 EST43091.1 - 0.22 11.3 11.7 0.47 10.2 11.7 1.7 1 1 0 1 1 1 0 Cytidylyltransferase family Myb_DNA-bind_6 PF13921.6 EST43092.1 - 1.6e-05 25.1 0.0 2.6e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EST43092.1 - 0.0005 20.2 0.0 0.0011 19.1 0.0 1.6 1 1 0 1 1 1 1 Myb-like DNA-binding domain EndoU_bacteria PF14436.6 EST43092.1 - 0.16 12.4 0.0 0.16 12.3 0.0 1.1 1 0 0 1 1 1 0 Bacterial EndoU nuclease DeoC PF01791.9 EST43093.1 - 1e-18 67.8 2.9 1.3e-18 67.5 2.9 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase His_biosynth PF00977.21 EST43093.1 - 0.013 15.0 0.4 0.025 14.1 0.4 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein NanE PF04131.14 EST43093.1 - 0.017 14.3 0.6 0.029 13.6 0.5 1.3 1 1 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase EGF_2 PF07974.13 EST43094.1 - 0.0033 17.7 15.4 0.0033 17.7 15.4 12.7 11 3 1 12 12 12 3 EGF-like domain ThiF PF00899.21 EST43095.1 - 1.1e-40 139.5 0.0 1.3e-40 139.3 0.0 1.0 1 0 0 1 1 1 1 ThiF family UDPG_MGDP_dh_N PF03721.14 EST43095.1 - 6.8e-05 22.5 0.0 9.3e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 EST43095.1 - 0.034 14.0 0.0 0.046 13.6 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EST43095.1 - 0.035 14.3 0.0 0.049 13.8 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Ldh_1_N PF00056.23 EST43095.1 - 0.063 13.4 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ApbA PF02558.16 EST43095.1 - 0.12 12.0 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Spt4 PF06093.13 EST43096.1 - 0.057 13.5 0.3 0.097 12.8 0.3 1.3 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger DNA_RNApol_7kD PF03604.13 EST43096.1 - 0.076 12.7 0.6 0.13 12.0 0.6 1.4 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Ribosomal_S27e PF01667.17 EST43096.1 - 0.077 12.7 1.4 0.13 12.0 1.4 1.3 1 0 0 1 1 1 0 Ribosomal protein S27 RIX1 PF08167.12 EST43097.1 - 0.038 13.7 0.0 20 4.9 0.0 3.4 2 1 0 2 2 2 0 rRNA processing/ribosome biogenesis DUF4361 PF14274.6 EST43098.1 - 0.0007 19.9 1.0 0.0015 18.8 0.7 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4361) Vps39_2 PF10367.9 EST43098.1 - 0.0083 16.6 3.9 0.032 14.7 3.9 2.2 1 1 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-C2H2_4 PF13894.6 EST43098.1 - 0.058 14.3 1.3 0.19 12.7 1.3 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger SlyX PF04102.12 EST43098.1 - 4.1 8.1 7.8 0.91 10.2 2.2 2.4 1 1 1 2 2 2 0 SlyX DivIC PF04977.15 EST43098.1 - 5.4 6.9 8.7 0.71 9.7 1.3 2.4 1 1 1 2 2 2 0 Septum formation initiator DUF485 PF04341.12 EST43100.1 - 0.029 14.3 1.2 0.05 13.5 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF485 DUF3969 PF13108.6 EST43101.1 - 0.045 13.8 0.2 5.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3969) EF-hand_6 PF13405.6 EST43101.1 - 0.05 13.6 0.1 1.2 9.3 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain EphA2_TM PF14575.6 EST43101.1 - 0.13 13.1 0.0 0.35 11.8 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DHHC PF01529.20 EST43103.1 - 1.6e-13 50.9 13.0 1.6e-13 50.9 13.0 1.9 1 1 1 2 2 2 1 DHHC palmitoyltransferase FXa_inhibition PF14670.6 EST43103.1 - 7.4 6.9 12.8 0.86 9.9 6.8 2.3 2 1 0 2 2 2 0 Coagulation Factor Xa inhibitory site Myb_DNA-binding PF00249.31 EST43104.1 - 1.7e-16 60.2 0.8 1e-08 35.2 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST43104.1 - 2e-16 60.0 0.1 1.6e-11 44.3 0.0 2.4 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 EST43104.1 - 0.00065 19.7 0.0 0.33 11.0 0.0 2.2 2 0 0 2 2 2 2 SLIDE MADF_DNA_bdg PF10545.9 EST43104.1 - 0.0035 17.6 0.8 0.044 14.1 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like TC1 PF15063.6 EST43104.1 - 0.02 14.8 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Thyroid cancer protein 1 SANT_DAMP1_like PF16282.5 EST43104.1 - 0.073 13.3 0.5 2.6 8.3 0.0 2.7 2 1 1 3 3 3 0 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 EST43104.1 - 0.082 13.0 1.3 7.8 6.7 0.1 2.2 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain HAD_2 PF13419.6 EST43106.1 - 1.8e-26 93.3 0.1 2.5e-26 92.9 0.1 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EST43106.1 - 1.7e-12 48.1 0.3 2.6e-10 41.0 0.3 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EST43106.1 - 0.00066 19.7 0.0 0.001 19.1 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EST43106.1 - 0.00071 20.0 0.0 0.00099 19.6 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase LDcluster4 PF18306.1 EST43106.1 - 0.091 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 SLOG cluster4 family Ribosomal_L6 PF00347.23 EST43108.1 - 7e-17 61.9 1.0 6.7e-10 39.5 0.1 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 Myb_DNA-binding PF00249.31 EST43110.1 - 1e-15 57.7 0.8 3e-08 33.7 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST43110.1 - 3.9e-15 55.8 0.1 5.5e-11 42.5 0.0 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EST43110.1 - 0.0038 17.2 0.0 0.98 9.5 0.0 2.4 2 0 0 2 2 2 2 SLIDE MADF_DNA_bdg PF10545.9 EST43110.1 - 0.016 15.6 0.6 0.14 12.5 0.0 2.4 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Minor_capsid_1 PF10665.9 EST43110.1 - 0.052 13.8 0.2 0.11 12.7 0.2 1.5 1 0 0 1 1 1 0 Minor capsid protein TC1 PF15063.6 EST43110.1 - 0.061 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Thyroid cancer protein 1 Rap1_C PF11626.8 EST43110.1 - 3.3 7.9 5.0 20 5.3 1.1 3.0 3 1 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DJ-1_PfpI PF01965.24 EST43112.1 - 5.6e-31 107.6 0.9 6.3e-31 107.4 0.9 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 EST43112.1 - 0.00012 21.7 0.0 0.00016 21.4 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain LysR_substrate PF03466.20 EST43113.1 - 0.009 15.4 0.2 0.012 15.0 0.2 1.2 1 0 0 1 1 1 1 LysR substrate binding domain Ribosomal_L6 PF00347.23 EST43114.1 - 1.2e-17 64.3 1.0 2.7e-10 40.8 0.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Peptidase_S30 PF01577.16 EST43114.1 - 0.097 12.3 1.4 8.7 5.9 0.0 2.9 3 0 0 3 3 3 0 Potyvirus P1 protease DJ-1_PfpI PF01965.24 EST43117.1 - 0.0001 22.2 0.0 0.00011 22.0 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Ribosomal_L6 PF00347.23 EST43119.1 - 1.2e-17 64.3 1.0 2.7e-10 40.8 0.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Peptidase_S30 PF01577.16 EST43119.1 - 0.097 12.3 1.4 8.7 5.9 0.0 2.9 3 0 0 3 3 3 0 Potyvirus P1 protease Myb_DNA-binding PF00249.31 EST43120.1 - 1.4e-07 31.6 1.8 1.4e-05 25.2 0.3 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF3242 PF11586.8 EST43120.1 - 0.0014 18.4 1.5 0.0022 17.7 0.3 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF3242) HTH_AsnC-type PF13404.6 EST43120.1 - 0.081 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Myb_DNA-bind_5 PF13873.6 EST43120.1 - 0.19 11.8 6.3 0.21 11.7 1.1 2.8 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 EST43121.1 - 6.8e-13 48.6 3.0 1.4e-07 31.6 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST43121.1 - 1e-07 32.1 5.4 1.5e-06 28.3 0.6 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EST43121.1 - 0.00056 19.9 0.1 0.18 11.8 0.0 2.4 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_3 PF12776.7 EST43121.1 - 0.069 14.2 2.1 2.5 9.2 0.3 2.3 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF4327 PF14217.6 EST43121.1 - 0.83 9.8 5.5 15 5.9 0.1 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4327) DUF3781 PF12636.7 EST43122.1 - 0.082 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) AhpC-TSA PF00578.21 EST43124.1 - 3.5e-14 52.8 0.0 4.3e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 EST43124.1 - 1.9e-12 47.3 0.0 2.5e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 EST43124.1 - 7.4e-12 45.2 0.0 8.7e-12 45.0 0.0 1.0 1 0 0 1 1 1 1 Redoxin Thioredoxin PF00085.20 EST43124.1 - 4.4e-10 39.5 0.6 4.8e-09 36.1 0.5 1.9 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 EST43124.1 - 1.4e-05 25.5 0.1 1.9e-05 25.1 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 EST43124.1 - 0.0016 18.2 0.1 0.012 15.4 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 EST43124.1 - 0.0044 17.2 0.4 0.07 13.3 0.1 2.2 2 1 0 2 2 2 1 Thioredoxin-like DUF3662 PF12401.8 EST43124.1 - 0.078 13.4 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2662) Myb_DNA-binding PF00249.31 EST43126.1 - 4.9e-18 65.1 1.6 1.6e-16 60.2 0.4 2.7 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST43126.1 - 2.5e-13 50.0 1.2 8.4e-11 42.0 0.1 2.6 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 EST43126.1 - 0.00031 20.7 0.9 0.13 12.3 0.2 2.2 1 1 1 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 EST43126.1 - 0.00081 19.5 0.1 0.0016 18.6 0.1 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 EST43126.1 - 0.0018 18.1 0.9 0.0036 17.2 0.3 1.7 1 1 1 2 2 2 1 Myb DNA-binding like FB_lectin PF07367.11 EST43126.1 - 0.037 14.0 0.2 0.052 13.5 0.2 1.3 1 0 0 1 1 1 0 Fungal fruit body lectin EGF_2 PF07974.13 EST43128.1 - 0.0018 18.6 14.9 0.0018 18.6 14.9 20.3 16 2 2 18 18 18 13 EGF-like domain Syndecan PF01034.20 EST43128.1 - 0.065 13.2 0.4 0.15 12.0 0.4 1.5 1 0 0 1 1 1 0 Syndecan domain VSP PF03302.13 EST43129.1 - 5.9e-12 45.2 116.0 9.3e-08 31.3 43.9 4.4 1 1 4 5 5 5 5 Giardia variant-specific surface protein VSP PF03302.13 EST43130.1 - 1.1e-13 50.8 133.5 8e-07 28.3 34.9 6.0 1 1 4 5 5 5 4 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST43130.1 - 0.00056 20.0 136.2 0.071 13.3 13.1 9.4 1 1 6 8 8 8 7 Furin-like repeat, cysteine-rich DUF3703 PF12487.8 EST43132.1 - 0.021 14.7 0.1 0.036 13.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3703) Stevor PF17410.2 EST43132.1 - 0.022 14.3 1.0 0.022 14.3 1.0 1.9 2 1 0 2 2 2 0 Subtelomeric Variable Open Reading frame SKG6 PF08693.10 EST43132.1 - 0.26 10.7 4.5 0.44 10.0 4.5 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain ApeA_NTD1 PF18862.1 EST43135.1 - 0.074 12.6 0.0 0.076 12.6 0.0 1.0 1 0 0 1 1 1 0 ApeA N-terminal domain 1 TMF_TATA_bd PF12325.8 EST43136.1 - 0.0064 16.7 20.2 0.0064 16.7 20.2 8.9 3 3 6 9 9 9 3 TATA element modulatory factor 1 TATA binding HALZ PF02183.18 EST43136.1 - 0.037 14.3 0.6 0.037 14.3 0.6 11.0 12 0 0 12 12 12 0 Homeobox associated leucine zipper SCO1-SenC PF02630.14 EST43136.1 - 3.3 7.6 6.7 2.4 8.1 0.6 3.4 2 1 1 3 3 3 0 SCO1/SenC ASF1_hist_chap PF04729.13 EST43137.1 - 5.1e-08 33.0 0.2 7.2e-08 32.5 0.2 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone B2-adapt-app_C PF09066.10 EST43138.1 - 0.0011 19.0 0.3 0.0032 17.5 0.3 1.7 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain EphA2_TM PF14575.6 EST43139.1 - 0.013 16.3 1.2 0.075 13.9 0.3 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Stevor PF17410.2 EST43139.1 - 0.031 13.8 0.1 0.081 12.5 0.1 1.6 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF2434 PF10361.9 EST43139.1 - 0.08 11.9 0.4 0.18 10.8 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2434) Phage_GP20 PF06810.11 EST43141.1 - 0.0013 18.5 6.1 0.0013 18.5 6.1 8.3 1 1 5 7 7 7 3 Phage minor structural protein GP20 Cnn_1N PF07989.11 EST43141.1 - 0.0015 18.7 1.0 0.0015 18.7 1.0 10.3 4 3 6 10 10 10 2 Centrosomin N-terminal motif 1 DUF5631 PF18645.1 EST43141.1 - 0.23 11.9 9.3 3.5 8.1 0.5 4.4 4 1 2 6 6 6 0 Family of unknown function (DUF5631) Ribosomal_L30 PF00327.20 EST43142.1 - 1e-13 51.0 0.7 1.6e-13 50.3 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 EST43142.1 - 1.1e-05 25.6 2.5 1.1e-05 25.6 2.5 1.7 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain CDP-OH_P_transf PF01066.21 EST43143.1 - 5.5e-11 43.1 1.1 5.5e-11 43.1 1.1 3.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase ELMO_CED12 PF04727.13 EST43144.1 - 1.3e-05 25.4 0.0 1.6e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family vATP-synt_AC39 PF01992.16 EST43145.1 - 6.2e-48 164.0 0.4 7.2e-48 163.8 0.4 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit STAT1_TAZ2bind PF12162.8 EST43145.1 - 0.15 11.6 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 STAT1 TAZ2 binding domain DUF3915 PF13054.6 EST43147.1 - 0.13 12.2 1.0 0.17 11.9 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) bZIP_2 PF07716.15 EST43147.1 - 0.52 10.4 17.9 0.055 13.6 11.8 2.4 2 0 0 2 2 2 0 Basic region leucine zipper Ribonuc_L-PSP PF01042.21 EST43148.1 - 1.5e-19 70.2 0.2 1.7e-19 70.0 0.2 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF5640 PF18692.1 EST43149.1 - 0.13 12.3 1.3 12 6.0 0.0 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5640) EGF PF00008.27 EST43150.1 - 0.014 15.7 7.2 0.014 15.7 7.2 16.2 15 2 0 15 15 15 0 EGF-like domain Stevor PF17410.2 EST43151.1 - 0.0087 15.6 0.1 0.018 14.6 0.1 1.5 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame DUF2434 PF10361.9 EST43151.1 - 0.13 11.2 3.4 0.061 12.3 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2434) DUF4690 PF15756.5 EST43151.1 - 0.16 12.6 6.3 0.065 13.8 3.5 1.8 2 0 0 2 2 2 0 Small Novel Rich in Cartilage EphA2_TM PF14575.6 EST43151.1 - 0.2 12.6 0.2 0.51 11.3 0.2 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 EST43151.1 - 1.5 8.8 3.3 2.5 8.1 3.3 1.3 1 0 0 1 1 1 0 Syndecan domain CTX_RstB PF07459.11 EST43158.1 - 0.0025 18.0 0.2 0.0041 17.3 0.2 1.4 1 1 0 1 1 1 1 CTX phage RstB protein PAS_7 PF12860.7 EST43158.1 - 0.0028 17.8 0.0 0.0038 17.4 0.0 1.3 1 0 0 1 1 1 1 PAS fold DUF3251 PF11622.8 EST43158.1 - 0.08 12.6 0.3 0.1 12.2 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) Phage_TAC_6 PF09550.10 EST43159.1 - 0.091 13.2 0.0 0.16 12.5 0.0 1.4 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC Flp_N PF03930.14 EST43159.1 - 0.54 10.3 2.9 17 5.4 1.2 2.5 2 0 0 2 2 2 0 Recombinase Flp protein N-terminus VSP PF03302.13 EST43162.1 - 9.6e-05 21.4 91.6 0.0059 15.5 45.9 3.1 1 1 1 2 2 2 2 Giardia variant-specific surface protein DUF3624 PF12292.8 EST43162.1 - 0.065 13.6 0.2 0.065 13.6 0.2 3.7 3 2 0 3 3 3 0 Protein of unknown function (DUF3624) Podoplanin PF05808.11 EST43162.1 - 0.33 11.0 0.7 0.45 10.6 0.1 1.5 2 0 0 2 2 2 0 Podoplanin DUF3498 PF12004.8 EST43163.1 - 0.25 10.5 2.3 0.56 9.3 2.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3498) VSP PF03302.13 EST43164.1 - 8e-14 51.3 319.2 0.00097 18.1 27.3 10.8 1 1 10 11 11 11 8 Giardia variant-specific surface protein cEGF PF12662.7 EST43165.1 - 0.1 12.6 0.5 0.1 12.6 0.5 6.4 6 1 0 6 6 6 0 Complement Clr-like EGF-like VSP PF03302.13 EST43165.1 - 0.27 10.1 102.1 0.13 11.1 38.3 5.0 1 1 3 4 4 4 0 Giardia variant-specific surface protein VSP PF03302.13 EST43166.1 - 3.8e-16 58.9 338.6 0.00067 18.6 26.9 10.5 1 1 9 10 10 10 8 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST43166.1 - 0.00044 20.4 17.7 0.00044 20.4 17.7 12.5 1 1 9 10 10 10 2 Furin-like repeat, cysteine-rich Trs65 PF12735.7 EST43168.1 - 0.011 15.2 0.1 0.012 15.1 0.1 1.1 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 VSP PF03302.13 EST43169.1 - 0.00045 19.2 40.1 0.00045 19.2 40.1 2.1 1 1 1 2 2 2 1 Giardia variant-specific surface protein VSP PF03302.13 EST43173.1 - 1.2e-07 30.9 261.3 0.0093 14.9 27.6 9.4 1 1 8 9 9 9 7 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST43173.1 - 0.0085 16.2 18.2 0.0085 16.2 18.2 11.9 1 1 10 11 11 11 3 Furin-like repeat, cysteine-rich Podoplanin PF05808.11 EST43173.1 - 0.79 9.8 6.3 0.14 12.3 0.3 2.7 2 1 1 3 3 3 0 Podoplanin ATP-synt_C PF00137.21 EST43174.1 - 5.6e-24 84.3 33.0 9.9e-18 64.3 14.5 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Enolase_N PF03952.16 EST43175.1 - 0.03 14.5 1.4 0.039 14.1 1.4 1.1 1 0 0 1 1 1 0 Enolase, N-terminal domain HU-CCDC81_bac_2 PF18175.1 EST43175.1 - 0.12 12.3 0.8 0.58 10.1 0.0 2.0 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 2 NapD PF03927.13 EST43175.1 - 0.28 11.3 3.5 4.7 7.3 0.1 2.1 1 1 1 2 2 2 0 NapD protein ABC_tran_CTD PF16326.5 EST43175.1 - 0.28 11.5 8.6 1.3 9.4 7.5 2.3 2 1 1 3 3 3 0 ABC transporter C-terminal domain Ank_2 PF12796.7 EST43179.1 - 2.1e-27 95.5 0.9 1.6e-09 38.2 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EST43179.1 - 1e-18 66.8 0.0 0.0014 19.0 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 EST43179.1 - 1e-16 59.3 0.3 0.00011 22.3 0.0 6.4 5 1 1 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 EST43179.1 - 1.4e-13 51.0 1.0 0.00033 21.2 0.0 4.6 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EST43179.1 - 8.3e-13 48.3 0.2 0.00047 20.4 0.0 4.8 3 2 2 5 5 5 2 Ankyrin repeats (many copies) NAD_binding_6 PF08030.12 EST43179.1 - 0.0043 17.2 0.2 0.11 12.6 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 EST43179.1 - 0.057 14.1 0.0 0.23 12.1 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF3324 PF11797.8 EST43179.1 - 0.091 12.7 0.3 1.8 8.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function C-terminal (DUF3324) Helicase_PWI PF18149.1 EST43179.1 - 0.12 12.5 2.8 0.67 10.2 0.1 2.8 3 0 0 3 3 3 0 N-terminal helicase PWI domain DUF1870 PF08965.10 EST43180.1 - 4.8 7.2 8.0 4.1 7.5 0.0 4.9 4 1 1 5 5 5 0 Domain of unknown function (DUF1870) Fer4 PF00037.27 EST43182.1 - 2.8e-08 33.2 29.6 4.8e-06 26.2 7.5 2.1 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 EST43182.1 - 1.8e-05 24.8 22.3 2.3e-05 24.4 22.3 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 EST43182.1 - 3.8e-05 23.7 25.3 0.00014 22.0 25.3 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 EST43182.1 - 4.7e-05 23.2 19.5 0.00039 20.3 3.9 2.7 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_7 PF12838.7 EST43182.1 - 0.00012 22.5 23.1 0.00045 20.8 23.3 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 EST43182.1 - 0.00038 20.5 23.5 0.0011 19.0 22.0 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 EST43182.1 - 0.00068 20.5 23.6 0.00069 20.5 4.5 2.1 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_4 PF12800.7 EST43182.1 - 0.0033 17.8 25.4 0.13 12.8 6.3 2.6 2 2 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 EST43182.1 - 0.0099 15.9 28.3 0.085 13.0 7.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_3 PF12798.7 EST43182.1 - 0.02 15.8 4.1 0.02 15.8 4.1 2.7 2 2 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.6 EST43182.1 - 0.029 14.8 22.3 0.13 12.7 4.2 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 EST43182.1 - 0.06 14.1 3.8 0.06 14.1 3.8 2.8 1 1 2 3 3 2 0 4Fe-4S single cluster domain Fer4_17 PF13534.6 EST43182.1 - 0.11 13.1 20.7 33 5.1 9.8 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 EST43182.1 - 0.5 10.6 20.0 2 8.6 18.5 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 EST43182.1 - 2 9.3 22.5 0.21 12.5 4.9 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Thioredoxin PF00085.20 EST43183.1 - 1.2e-26 92.7 0.6 4.9e-23 81.1 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 EST43183.1 - 6.5e-12 45.7 1.5 2.7e-08 34.0 3.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 EST43183.1 - 0.0016 18.9 0.1 0.011 16.2 0.0 2.4 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EST43183.1 - 0.032 14.5 0.6 2.8 8.3 0.0 2.8 2 1 1 3 3 3 0 Thioredoxin-like Thioredoxin_9 PF14595.6 EST43183.1 - 0.11 12.3 0.2 0.29 10.9 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin DUF4318 PF14201.6 EST43184.1 - 0.12 12.9 1.3 1.8 9.1 0.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4318) Thioredoxin_8 PF13905.6 EST43185.1 - 0.029 14.7 0.4 0.046 14.1 0.4 1.3 1 0 0 1 1 1 0 Thioredoxin-like DUF3037 PF11236.8 EST43186.1 - 0.025 15.0 1.9 0.04 14.4 1.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3037) FAM76 PF16046.5 EST43186.1 - 0.32 10.3 10.6 0.35 10.2 10.6 1.1 1 0 0 1 1 1 0 FAM76 protein RRP36 PF06102.12 EST43186.1 - 1.3 9.0 5.0 1.5 8.8 5.0 1.2 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 XhlA PF10779.9 EST43186.1 - 1.4 9.1 15.4 0.11 12.7 7.8 2.4 2 0 0 2 2 2 0 Haemolysin XhlA Lipase_GDSL_3 PF14606.6 EST43186.1 - 6.6 6.8 11.4 9.5 6.3 11.1 1.3 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family AA_permease_2 PF13520.6 EST43187.1 - 7.7e-25 87.6 39.2 1.1e-24 87.1 37.9 1.6 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.21 EST43187.1 - 7.8e-06 24.8 23.0 7.8e-06 24.8 23.0 3.3 1 1 1 2 2 2 1 Amino acid permease CobD_Cbib PF03186.13 EST43187.1 - 2.2 7.4 5.7 0.72 9.0 0.2 2.7 1 1 1 3 3 3 0 CobD/Cbib protein Sugar_tr PF00083.24 EST43188.1 - 3.7e-57 194.2 35.9 3.8e-39 134.8 13.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EST43188.1 - 1.8e-14 53.4 39.8 1.8e-11 43.6 30.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EST43188.1 - 0.025 13.0 12.2 0.011 14.2 9.4 1.7 1 1 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Myb_DNA-binding PF00249.31 EST43189.1 - 3e-06 27.3 0.2 4.5e-06 26.7 0.2 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST43189.1 - 1.1e-05 25.6 2.2 1.5e-05 25.2 2.2 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST43189.1 - 0.095 12.6 3.6 0.12 12.3 3.6 1.3 1 1 0 1 1 1 0 Myb DNA-binding like DUF2098 PF09871.9 EST43189.1 - 0.56 10.6 3.3 1.2 9.5 3.3 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) DHC_N2 PF08393.13 EST43190.1 - 3.1e-108 362.4 27.1 3.1e-108 362.4 27.1 5.4 5 1 1 6 6 4 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 EST43190.1 - 2.4e-94 316.0 24.9 3.4e-94 315.5 0.8 6.5 5 1 0 5 5 4 1 Hydrolytic ATP binding site of dynein motor region Dynein_C PF18199.1 EST43190.1 - 3.4e-84 282.7 0.5 1.8e-83 280.3 0.0 2.6 2 1 0 2 2 1 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 EST43190.1 - 3.4e-82 275.7 6.3 7.6e-80 268.0 4.6 3.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 EST43190.1 - 1.1e-64 217.3 3.1 4.4e-63 212.1 0.0 3.9 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_9 PF12781.7 EST43190.1 - 2.4e-58 196.9 12.2 2.4e-58 196.9 12.2 5.9 5 0 0 5 5 5 1 ATP-binding dynein motor region MT PF12777.7 EST43190.1 - 2.6e-47 161.5 11.1 5.7e-47 160.4 11.1 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 EST43190.1 - 2.2e-34 118.1 0.7 2.5e-32 111.5 0.1 3.8 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 EST43190.1 - 3e-34 118.2 1.0 9.1e-33 113.4 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_AAA_lid PF17852.1 EST43190.1 - 1.4e-16 60.7 0.9 1.4e-16 60.7 0.9 3.6 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 EST43190.1 - 1.2e-13 51.2 0.0 0.002 18.1 0.0 6.0 4 2 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 EST43190.1 - 2.6e-12 46.8 3.2 7.6e-11 42.1 1.0 4.1 2 1 0 2 2 2 1 AAA+ lid domain AAA_22 PF13401.6 EST43190.1 - 4.8e-05 23.7 1.8 0.014 15.7 0.0 4.5 3 1 1 4 4 3 1 AAA domain Mg_chelatase PF01078.21 EST43190.1 - 0.0011 18.4 0.0 0.3 10.4 0.0 3.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA PF00004.29 EST43190.1 - 0.0046 17.4 1.0 39 4.7 0.0 5.0 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EST43190.1 - 0.0058 16.4 0.1 0.5 10.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 EST43190.1 - 0.016 15.6 0.0 1.2 9.5 0.0 3.5 3 0 0 3 3 3 0 AAA ATPase domain AAA_33 PF13671.6 EST43190.1 - 0.019 15.1 0.0 4.2 7.5 0.0 3.9 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 EST43190.1 - 0.023 14.1 0.6 0.26 10.6 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family T2SSE PF00437.20 EST43190.1 - 0.037 13.1 0.0 0.037 13.1 0.0 4.4 5 0 0 5 5 5 0 Type II/IV secretion system protein Sigma54_activat PF00158.26 EST43190.1 - 0.066 12.9 0.0 3.5 7.3 0.0 3.3 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_19 PF13245.6 EST43190.1 - 0.22 11.8 1.3 2.7 8.3 0.0 3.5 4 0 0 4 4 2 0 AAA domain UvrC_HhH_N PF08459.11 EST43190.1 - 0.29 11.0 2.7 0.5 10.3 0.0 2.6 2 0 0 2 2 2 0 UvrC Helix-hairpin-helix N-terminal DUF2730 PF10805.8 EST43190.1 - 0.42 10.7 5.9 0.65 10.1 0.2 4.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) DUF3323 PF11796.8 EST43190.1 - 0.71 9.7 4.1 1.7 8.4 4.1 1.6 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) DEAD PF00270.29 EST43190.1 - 1.5 8.6 7.2 0.8 9.5 0.0 4.0 5 0 0 5 5 3 0 DEAD/DEAH box helicase DUF5325 PF17259.2 EST43191.1 - 0.00065 19.5 4.4 0.0011 18.8 4.4 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5325) Comm PF15957.5 EST43191.1 - 0.086 13.2 0.1 6.2 7.2 0.0 2.4 2 0 0 2 2 2 0 Commissureless Sugar_tr PF00083.24 EST43192.1 - 3.5e-56 190.9 36.1 5.8e-39 134.2 13.9 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EST43192.1 - 2.8e-15 56.1 40.1 1.9e-12 46.8 34.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EST43192.1 - 0.016 14.5 16.2 0.02 14.2 14.7 1.7 1 1 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 EST43192.1 - 0.26 9.6 14.8 0.11 10.9 11.8 1.8 1 1 1 2 2 2 0 Fungal trichothecene efflux pump (TRI12) EspB_PE PF18625.1 EST43194.1 - 0.2 12.1 0.0 0.29 11.6 0.0 1.3 1 0 0 1 1 1 0 ESX-1 secreted protein B PE domain Proteasome PF00227.26 EST43195.1 - 3.7e-12 46.1 0.0 4.4e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Peptidase_C1 PF00112.23 EST43196.1 - 7.7e-32 111.1 5.7 3.1e-31 109.2 5.7 1.9 1 1 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EST43196.1 - 0.00041 19.2 2.1 0.037 12.8 0.5 2.4 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C39_2 PF13529.6 EST43196.1 - 0.37 11.3 3.4 4 8.0 3.4 2.5 1 1 0 1 1 1 0 Peptidase_C39 like family Tubulin PF00091.25 EST43197.1 - 1e-68 231.4 0.0 1.7e-68 230.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EST43197.1 - 3.5e-40 137.1 0.0 5.3e-40 136.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EST43197.1 - 5.1e-05 23.6 0.0 0.00021 21.6 0.0 1.9 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EST43197.1 - 0.0045 16.7 0.0 0.0082 15.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 EST43197.1 - 0.014 14.6 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 Tubulin like Myb_DNA-binding PF00249.31 EST43198.1 - 7.3e-07 29.3 0.1 1e-06 28.8 0.1 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST43198.1 - 2.4e-05 24.5 0.8 3e-05 24.2 0.8 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EST43198.1 - 0.0029 17.8 0.8 0.005 17.0 0.8 1.4 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 EST43198.1 - 0.028 14.3 1.2 0.036 13.9 1.2 1.3 1 1 0 1 1 1 0 Myb DNA-binding like Sugar_tr PF00083.24 EST43199.1 - 3e-57 194.5 35.3 5.1e-40 137.7 13.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EST43199.1 - 1.5e-15 57.0 53.4 4.3e-14 52.2 30.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EST43199.1 - 0.0012 17.3 4.2 0.0012 17.3 4.2 2.0 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 EST43199.1 - 0.0075 15.6 16.2 0.038 13.3 16.2 2.0 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB PSDC PF12588.8 EST43200.1 - 0.005 16.8 4.2 0.5 10.3 0.2 3.9 3 1 0 4 4 4 2 Phophatidylserine decarboxylase SANT_DAMP1_like PF16282.5 EST43200.1 - 0.038 14.2 3.1 0.51 10.6 0.6 3.2 3 0 0 3 3 3 0 SANT/Myb-like domain of DAMP1 Nucleolin_bd PF16725.5 EST43200.1 - 0.46 10.2 0.0 0.46 10.2 0.0 2.9 3 0 0 3 3 3 0 Nucleolin binding domain Nucleolin_bd PF16725.5 EST43201.1 - 0.00011 21.8 0.1 1.1 9.0 0.0 3.2 2 0 0 2 2 2 2 Nucleolin binding domain XTBD PF11952.8 EST43201.1 - 0.0041 16.8 0.2 14 5.5 0.0 3.9 3 0 0 3 3 3 2 XRN-Two Binding Domain, XTBD DNA_PPF PF02916.15 EST43201.1 - 0.0088 16.4 10.2 0.5 10.8 0.7 3.3 3 0 0 3 3 3 2 DNA polymerase processivity factor DUF5327 PF17261.2 EST43201.1 - 0.34 11.7 3.5 19 6.1 0.4 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5327) NBD94 PF16830.5 EST43201.1 - 1 9.8 23.4 0.58 10.6 1.1 5.2 5 0 0 5 5 5 0 Nucleotide-Binding Domain 94 of RH SpoVIF PF14069.6 EST43201.1 - 1.4 8.8 9.8 13 5.6 0.5 4.0 3 0 0 3 3 3 0 Stage VI sporulation protein F Zip PF02535.22 EST43202.1 - 2.4e-28 99.4 17.0 1.6e-26 93.3 17.0 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter DUF872 PF05915.12 EST43202.1 - 0.73 10.0 4.8 1.5 9.0 0.3 3.1 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF872) Sugar_tr PF00083.24 EST43204.1 - 1.3e-57 195.7 35.5 1.2e-39 136.4 13.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EST43204.1 - 2e-15 56.6 54.8 2.2e-12 46.6 32.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EST43204.1 - 0.0015 17.0 3.9 0.0015 17.0 3.9 1.7 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) FlxA PF14282.6 EST43205.1 - 0.0069 16.4 5.8 0.0069 16.4 5.8 2.9 2 1 0 3 3 3 1 FlxA-like protein Vps54_N PF10475.9 EST43205.1 - 0.16 11.2 6.0 1 8.6 2.3 2.1 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex Abi_C PF14355.6 EST43205.1 - 0.17 12.0 1.6 1.7 8.8 0.3 2.2 2 0 0 2 2 2 0 Abortive infection C-terminus DUF4140 PF13600.6 EST43205.1 - 0.41 11.1 6.0 1 9.8 0.1 2.9 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF1690 PF07956.11 EST43205.1 - 0.55 10.7 12.8 18 5.7 0.1 2.9 2 1 0 2 2 2 0 Protein of Unknown function (DUF1690) Flagellin_N PF00669.20 EST43205.1 - 0.89 9.7 14.3 0.19 11.9 1.5 2.7 2 1 1 3 3 3 0 Bacterial flagellin N-terminal helical region bZIP_2 PF07716.15 EST43205.1 - 2.8 8.1 7.2 1 9.5 0.6 3.0 3 0 0 3 3 3 0 Basic region leucine zipper Occludin_ELL PF07303.13 EST43205.1 - 5.7 7.7 8.0 8.4 7.2 0.4 2.3 2 0 0 2 2 2 0 Occludin homology domain EVI2A PF05399.11 EST43209.1 - 0.078 12.6 0.1 0.11 12.1 0.1 1.1 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Vps26 PF03643.15 EST43211.1 - 8.6e-19 67.6 0.0 1.1e-18 67.3 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 DnaJ_C PF01556.18 EST43213.1 - 5.2e-38 130.5 0.3 6.8e-38 130.1 0.3 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EST43213.1 - 2.4e-16 59.6 0.1 3.9e-16 58.9 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Cyclin PF08613.11 EST43214.1 - 1.2e-08 35.4 0.2 1.4e-08 35.2 0.2 1.1 1 0 0 1 1 1 1 Cyclin VSP PF03302.13 EST43220.1 - 3.5e-07 29.4 42.2 3.5e-07 29.4 42.2 5.5 1 1 4 5 5 5 2 Giardia variant-specific surface protein PARM PF17061.5 EST43220.1 - 0.0038 17.4 0.3 0.0069 16.6 0.1 1.3 1 1 0 1 1 1 1 PARM Podoplanin PF05808.11 EST43220.1 - 3.7 7.6 10.3 51 3.9 10.2 2.5 1 1 0 1 1 1 0 Podoplanin Myb_DNA-binding PF00249.31 EST43221.1 - 0.002 18.3 0.3 0.0031 17.7 0.3 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST43221.1 - 0.0059 16.8 0.1 0.0079 16.4 0.1 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EST43221.1 - 0.05 14.0 1.7 0.19 12.1 1.7 1.9 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain Methyltr_RsmB-F PF01189.17 EST43224.1 - 4e-42 144.1 0.0 8.1e-42 143.1 0.0 1.5 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 EST43224.1 - 2.5e-06 27.7 0.0 5.2e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase AAA_13 PF13166.6 EST43226.1 - 0.0016 17.2 36.1 0.0016 17.2 36.1 3.7 1 1 1 2 2 2 2 AAA domain Tropomyosin_1 PF12718.7 EST43226.1 - 0.0029 17.8 10.9 0.0029 17.8 10.9 6.2 1 1 5 6 6 6 3 Tropomyosin like BLOC1_2 PF10046.9 EST43226.1 - 0.022 15.0 8.4 0.022 15.0 8.4 9.0 2 2 8 10 10 10 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Atg14 PF10186.9 EST43226.1 - 0.19 10.8 100.8 0.14 11.2 19.9 4.5 1 1 3 4 4 4 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 EST43226.1 - 0.22 10.4 105.4 0.12 11.2 27.4 4.7 1 1 3 4 4 4 0 Spc7 kinetochore protein Tropomyosin PF00261.20 EST43226.1 - 1.1 8.6 75.6 0.17 11.2 29.7 5.1 1 1 2 4 4 4 0 Tropomyosin Fez1 PF06818.15 EST43226.1 - 2.2 8.7 96.0 2 8.8 18.4 4.9 1 1 4 5 5 5 0 Fez1 Pkinase PF00069.25 EST43227.1 - 1.5e-54 185.2 0.0 1.8e-54 184.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST43227.1 - 6.7e-24 84.6 0.0 1.3e-23 83.6 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EST43227.1 - 0.022 14.7 0.0 1.4 8.7 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Colicin_M PF14859.6 EST43227.1 - 0.1 11.7 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Colicin M AhpC-TSA PF00578.21 EST43234.1 - 3.4e-32 111.0 0.0 4.6e-32 110.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EST43234.1 - 9.1e-11 41.7 0.0 1.4e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EST43234.1 - 5.6e-06 26.1 0.0 1.8e-05 24.5 0.1 1.9 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin VSP PF03302.13 EST43236.1 - 3.6e-07 29.4 41.7 3.6e-07 29.4 41.7 4.5 1 1 3 4 4 4 2 Giardia variant-specific surface protein PARM PF17061.5 EST43236.1 - 0.0028 17.8 0.2 0.0058 16.8 0.1 1.4 1 1 0 1 1 1 1 PARM Podoplanin PF05808.11 EST43236.1 - 0.18 11.9 7.1 0.27 11.3 5.3 2.2 1 1 0 1 1 1 0 Podoplanin HTH_AraC PF00165.23 EST43239.1 - 0.074 13.2 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family SNF2_N PF00176.23 EST43248.1 - 1.8e-39 135.5 0.4 1.8e-39 135.5 0.4 2.4 4 0 0 4 4 4 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EST43248.1 - 1.6e-19 70.3 0.1 1.6e-19 70.3 0.1 3.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain PHD_2 PF13831.6 EST43248.1 - 1.7e-06 27.5 5.4 1.7e-06 27.5 5.4 2.7 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 EST43248.1 - 3.3e-05 23.7 20.7 0.0025 17.7 9.3 2.8 2 0 0 2 2 2 2 PHD-finger C1_1 PF00130.22 EST43248.1 - 0.0022 17.8 6.8 0.0022 17.8 6.8 3.4 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.6 EST43248.1 - 1.9 8.8 19.6 0.36 11.1 2.4 3.1 2 0 0 2 2 2 0 PHD-like zinc-binding domain HydF_dimer PF18128.1 EST43251.1 - 0.23 11.6 2.9 16 5.7 0.4 3.0 2 1 0 2 2 2 0 Hydrogen maturase F dimerization domain HydF_tetramer PF18133.1 EST43253.1 - 1.3e-29 102.3 0.2 3.7e-29 100.9 0.1 1.8 2 0 0 2 2 2 1 Hydrogen maturase F tetramerization domain MMR_HSR1 PF01926.23 EST43253.1 - 1.4e-17 63.8 0.3 3.2e-17 62.7 0.3 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase HydF_dimer PF18128.1 EST43253.1 - 2.4e-10 40.4 1.4 4.2e-09 36.4 0.4 3.2 3 1 0 3 3 3 1 Hydrogen maturase F dimerization domain Dynamin_N PF00350.23 EST43253.1 - 2.2e-07 31.1 0.1 1.6e-06 28.3 0.1 2.2 1 1 0 1 1 1 1 Dynamin family FeoB_N PF02421.18 EST43253.1 - 1.5e-06 27.9 0.0 3.1e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B dNK PF01712.19 EST43253.1 - 0.06 13.2 0.4 4.2 7.2 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase CTP_synth_N PF06418.14 EST43256.1 - 2.7e-111 371.1 0.1 4e-111 370.6 0.1 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 EST43256.1 - 1.9e-53 181.1 0.1 3e-53 180.5 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EST43256.1 - 5.3e-09 36.2 0.1 7.8e-08 32.3 0.0 2.4 1 1 1 2 2 2 1 Peptidase C26 DUF3307 PF11750.8 EST43257.1 - 4e-11 43.1 0.2 5e-11 42.8 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3307) Tyr_Deacylase PF02580.16 EST43257.1 - 0.19 12.2 0.0 0.22 12.0 0.0 1.3 1 0 0 1 1 1 0 D-Tyr-tRNA(Tyr) deacylase zf-C4_ClpX PF06689.13 EST43258.1 - 0.017 15.0 0.7 0.017 15.0 0.7 4.2 5 0 0 5 5 5 0 ClpX C4-type zinc finger FUSC PF04632.12 EST43260.1 - 2.3 6.7 6.0 2.7 6.4 6.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF966 PF06136.13 EST43260.1 - 4.7 6.8 20.3 5.5 6.6 20.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) GLE1 PF07817.13 EST43260.1 - 8.2 5.6 23.9 0.57 9.3 13.5 2.2 2 0 0 2 2 2 0 GLE1-like protein DUF4407 PF14362.6 EST43260.1 - 9 5.5 33.7 16 4.7 33.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) SH3_6 PF12913.7 EST43262.1 - 0.016 14.7 4.0 8 6.1 0.1 3.2 3 0 0 3 3 3 0 SH3 domain (SH3b1 type) Sporozoite_P67 PF05642.11 EST43262.1 - 0.04 12.0 0.8 0.044 11.9 0.8 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen zf-C4_ClpX PF06689.13 EST43263.1 - 0.017 15.0 0.7 0.017 15.0 0.7 4.2 5 0 0 5 5 5 0 ClpX C4-type zinc finger DUF3307 PF11750.8 EST43264.1 - 4e-11 43.1 0.2 5e-11 42.8 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3307) Tyr_Deacylase PF02580.16 EST43264.1 - 0.19 12.2 0.0 0.22 12.0 0.0 1.3 1 0 0 1 1 1 0 D-Tyr-tRNA(Tyr) deacylase AAA_21 PF13304.6 EST43265.1 - 5.9e-07 29.6 0.0 1.1e-06 28.7 0.0 1.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SLS PF14611.6 EST43265.1 - 0.00084 19.2 0.0 0.0012 18.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator SNase PF00565.17 EST43266.1 - 1.9e-20 73.3 8.2 2e-05 25.0 0.2 4.7 4 0 0 4 4 4 4 Staphylococcal nuclease homologue TUDOR PF00567.24 EST43266.1 - 4.1e-05 23.6 0.2 0.00023 21.2 0.1 2.5 2 0 0 2 2 2 1 Tudor domain GTP_EFTU PF00009.27 EST43267.1 - 3.7e-55 186.5 0.0 4.5e-55 186.2 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EST43267.1 - 2.3e-32 111.6 0.0 8.2e-32 109.8 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EST43267.1 - 1.8e-13 50.6 0.1 4.1e-13 49.5 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EST43267.1 - 0.0001 22.3 0.5 0.0017 18.4 0.5 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EST43267.1 - 0.00093 18.6 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU_D4 PF14578.6 EST43267.1 - 0.024 14.6 0.1 0.064 13.2 0.1 1.7 1 0 0 1 1 1 0 Elongation factor Tu domain 4 Dynamin_N PF00350.23 EST43267.1 - 0.051 13.6 0.2 12 5.9 0.0 2.6 2 1 0 2 2 2 0 Dynamin family Septin PF00735.18 EST43267.1 - 0.078 12.2 0.0 0.19 11.0 0.0 1.6 1 1 0 1 1 1 0 Septin SRPRB PF09439.10 EST43267.1 - 0.09 12.2 0.4 0.39 10.1 0.1 2.2 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit Amelogenin PF02948.15 EST43267.1 - 0.11 13.1 0.5 0.21 12.2 0.0 1.6 2 0 0 2 2 2 0 Amelogenin UPF0160 PF03690.13 EST43268.1 - 1.9e-63 215.0 6.7 1.3e-61 209.0 6.7 2.1 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0160) ABC_tran PF00005.27 EST43269.1 - 2.9e-19 70.0 0.0 6e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EST43269.1 - 2.4e-08 33.7 1.0 5.8e-06 25.9 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EST43269.1 - 5.2e-07 30.4 0.8 5.2e-07 30.4 0.8 2.6 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EST43269.1 - 0.0012 18.5 0.0 0.0031 17.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Sigma54_activat PF00158.26 EST43269.1 - 0.0016 18.2 0.1 2.1 8.0 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 EST43269.1 - 0.0057 16.9 0.6 0.032 14.5 0.1 2.4 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EST43269.1 - 0.024 14.5 0.9 0.081 12.8 0.1 2.0 2 0 0 2 2 2 0 RsgA GTPase TniB PF05621.11 EST43269.1 - 0.028 13.8 0.2 0.18 11.2 0.1 2.2 2 0 0 2 2 2 0 Bacterial TniB protein ABC_ATPase PF09818.9 EST43269.1 - 0.046 12.5 0.9 0.27 10.0 0.0 2.3 3 0 0 3 3 3 0 Predicted ATPase of the ABC class NACHT PF05729.12 EST43269.1 - 0.058 13.3 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 EST43269.1 - 0.072 12.8 0.0 0.13 11.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain UPF0160 PF03690.13 EST43270.1 - 1.9e-63 215.0 6.7 1.3e-61 209.0 6.7 2.1 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0160) GTP_EFTU PF00009.27 EST43271.1 - 3.7e-55 186.5 0.0 4.5e-55 186.2 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EST43271.1 - 2.3e-32 111.6 0.0 8.2e-32 109.8 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EST43271.1 - 1.8e-13 50.6 0.1 4.1e-13 49.5 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EST43271.1 - 0.0001 22.3 0.5 0.0017 18.4 0.5 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EST43271.1 - 0.00093 18.6 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU_D4 PF14578.6 EST43271.1 - 0.024 14.6 0.1 0.064 13.2 0.1 1.7 1 0 0 1 1 1 0 Elongation factor Tu domain 4 Dynamin_N PF00350.23 EST43271.1 - 0.051 13.6 0.2 12 5.9 0.0 2.6 2 1 0 2 2 2 0 Dynamin family Septin PF00735.18 EST43271.1 - 0.078 12.2 0.0 0.19 11.0 0.0 1.6 1 1 0 1 1 1 0 Septin SRPRB PF09439.10 EST43271.1 - 0.09 12.2 0.4 0.39 10.1 0.1 2.2 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit Amelogenin PF02948.15 EST43271.1 - 0.11 13.1 0.5 0.21 12.2 0.0 1.6 2 0 0 2 2 2 0 Amelogenin DUF3042 PF11240.8 EST43272.1 - 0.21 11.7 0.1 0.64 10.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) Pkinase PF00069.25 EST43273.1 - 8.2e-25 87.7 0.0 1.4e-24 86.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST43273.1 - 7.1e-11 41.9 0.0 1.7e-10 40.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EST43273.1 - 0.029 13.7 0.1 0.05 13.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EST43273.1 - 0.12 12.3 0.0 1.1 9.1 0.0 2.4 3 0 0 3 3 3 0 Phosphotransferase enzyme family GTP_EFTU PF00009.27 EST43274.1 - 4.8e-37 127.4 0.1 1.2e-36 126.0 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EST43274.1 - 8.5e-18 64.7 0.6 2.3e-17 63.3 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain N36 PF11438.8 EST43274.1 - 1.1 9.2 5.1 8.9 6.2 4.0 2.7 2 0 0 2 2 2 0 36-mer N-terminal peptide of the N protein (N36) SRP-alpha_N PF04086.13 EST43274.1 - 3.4 7.5 8.1 5.1 6.9 8.1 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal MFS_1 PF07690.16 EST43275.1 - 1.1e-26 93.6 23.2 1.5e-26 93.1 23.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EST43275.1 - 2.7e-12 46.3 23.4 4.8e-07 29.0 10.3 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 EST43275.1 - 2.8e-10 39.3 27.6 3.5e-05 22.6 11.5 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein PCI PF01399.27 EST43276.1 - 2.1e-05 25.0 0.8 5.6e-05 23.6 0.1 2.2 2 0 0 2 2 2 1 PCI domain DUF4568 PF15132.6 EST43276.1 - 0.03 13.7 0.1 0.056 12.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4568) DUF1322 PF07032.11 EST43276.1 - 0.077 13.5 0.6 18 5.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1322) RSV_NS2 PF03113.14 EST43276.1 - 0.15 12.1 0.4 0.43 10.6 0.2 1.9 2 0 0 2 2 2 0 Respiratory synctial virus non-structural protein NS2 Peptidase_M20 PF01546.28 EST43277.1 - 4.9e-08 32.9 0.0 7.9e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EST43277.1 - 6.1e-06 26.1 0.0 1.3e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M18 PF02127.15 EST43277.1 - 0.039 12.8 0.0 0.075 11.8 0.0 1.4 1 0 0 1 1 1 0 Aminopeptidase I zinc metalloprotease (M18) Oxidored_FMN PF00724.20 EST43278.1 - 5.1e-32 111.5 0.5 1.4e-29 103.5 0.5 2.1 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 EST43278.1 - 0.0088 15.5 0.0 0.14 11.5 0.0 2.3 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel SRP54 PF00448.22 EST43279.1 - 1e-50 172.1 0.1 2e-50 171.2 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 EST43279.1 - 7.7e-06 26.0 0.0 2.9e-05 24.2 0.0 2.0 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain SRP-alpha_N PF04086.13 EST43279.1 - 0.00011 22.3 7.1 0.00011 22.3 6.3 1.4 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal NTPase_1 PF03266.15 EST43279.1 - 0.0005 20.0 1.6 0.065 13.1 1.6 2.8 1 1 0 1 1 1 1 NTPase AAA_22 PF13401.6 EST43279.1 - 0.0017 18.6 0.8 0.017 15.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EST43279.1 - 0.0092 15.7 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EST43279.1 - 0.016 15.6 1.6 0.054 13.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain Metallophos_3 PF14582.6 EST43279.1 - 0.032 13.6 0.0 0.061 12.6 0.0 1.4 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily MMR_HSR1 PF01926.23 EST43279.1 - 0.039 14.0 2.2 0.16 12.1 0.5 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.12 EST43279.1 - 0.045 13.7 0.1 0.22 11.4 0.1 2.1 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.6 EST43279.1 - 0.067 13.5 0.0 0.21 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain BRF1 PF07741.13 EST43279.1 - 0.18 12.2 5.3 0.39 11.1 5.3 1.6 1 0 0 1 1 1 0 Brf1-like TBP-binding domain AAA_16 PF13191.6 EST43279.1 - 0.18 12.2 0.6 0.59 10.5 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 EST43279.1 - 0.67 10.5 0.1 0.67 10.5 0.1 2.9 2 1 0 2 2 1 0 ABC transporter MobB PF03205.14 EST43279.1 - 2.1 8.2 4.0 0.97 9.3 0.5 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.23 EST43279.1 - 3.6 7.7 5.3 6.5 6.8 0.6 3.1 3 1 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain Mrr_cat_2 PF13156.6 EST43279.1 - 9.4 6.2 8.6 0.77 9.7 0.7 2.9 3 0 0 3 3 3 0 Restriction endonuclease Atg14 PF10186.9 EST43282.1 - 0.0068 15.5 3.0 0.0072 15.5 3.0 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Cnn_1N PF07989.11 EST43282.1 - 0.028 14.6 4.1 0.091 12.9 3.8 2.0 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 ADIP PF11559.8 EST43282.1 - 0.068 13.3 8.2 0.91 9.6 2.0 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Mo-nitro_C PF06967.11 EST43282.1 - 0.075 13.0 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 Mo-dependent nitrogenase C-terminus DUF4883 PF16224.5 EST43282.1 - 0.079 13.2 0.3 0.12 12.6 0.3 1.2 1 0 0 1 1 1 0 DOmain of unknown function (DUF4883) Baculo_PP31 PF05311.11 EST43282.1 - 0.13 11.7 0.1 0.17 11.3 0.1 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Guanylate_kin PF00625.21 EST43283.1 - 8.8e-41 139.6 1.4 1e-40 139.4 1.4 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.6 EST43283.1 - 0.00015 22.3 0.6 0.00044 20.8 0.6 1.8 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EST43283.1 - 0.00059 19.9 0.1 0.001 19.1 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EST43283.1 - 0.0023 18.5 0.3 0.004 17.7 0.3 1.6 1 1 0 1 1 1 1 ABC transporter AAA_14 PF13173.6 EST43283.1 - 0.0087 16.1 0.4 0.022 14.8 0.2 2.1 1 1 1 2 2 2 1 AAA domain dNK PF01712.19 EST43283.1 - 0.035 14.0 3.7 1.2 9.0 0.1 2.8 2 1 0 2 2 2 0 Deoxynucleoside kinase CpeS PF09367.10 EST43283.1 - 0.037 14.0 0.1 0.049 13.5 0.1 1.2 1 0 0 1 1 1 0 CpeS-like protein bPH_4 PF06713.11 EST43283.1 - 0.049 13.7 0.3 0.49 10.5 0.2 2.6 2 1 0 2 2 2 0 Bacterial PH domain AAA_33 PF13671.6 EST43283.1 - 0.078 13.1 1.0 1.5 9.0 1.0 2.5 1 1 0 1 1 1 0 AAA domain Guanylate_kin PF00625.21 EST43284.1 - 3.2e-39 134.5 0.2 4.5e-39 134.0 0.2 1.2 1 0 0 1 1 1 1 Guanylate kinase MMR_HSR1 PF01926.23 EST43284.1 - 0.0017 18.4 0.1 0.0035 17.4 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 EST43284.1 - 0.0025 18.3 0.3 0.01 16.4 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EST43284.1 - 0.015 15.3 0.5 0.042 13.9 0.3 1.9 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 EST43284.1 - 0.056 13.6 0.0 0.16 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EST43284.1 - 0.068 13.7 0.2 0.12 12.9 0.2 1.6 1 1 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 EST43284.1 - 0.1 12.5 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase TsaE PF02367.17 EST43284.1 - 0.1 12.6 0.1 3.4 7.7 0.0 2.7 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Desulfoferrod_N PF06397.12 EST43284.1 - 0.12 12.0 0.3 0.22 11.1 0.3 1.4 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain AAA_16 PF13191.6 EST43284.1 - 0.18 12.2 0.0 0.21 12.0 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain TM231 PF10149.9 EST43285.1 - 0.033 13.5 0.3 0.04 13.3 0.3 1.1 1 0 0 1 1 1 0 Transmembrane protein 231 HpaB PF03241.13 EST43286.1 - 0.005 15.9 0.0 0.013 14.6 0.0 1.6 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase C terminal Cloacin_immun PF03513.14 EST43286.1 - 0.038 14.3 0.2 0.37 11.2 0.2 2.9 1 0 0 1 1 1 0 Cloacin immunity protein DUF948 PF06103.11 EST43286.1 - 9.3 6.6 7.2 11 6.3 0.1 3.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) SATase_N PF06426.14 EST43287.1 - 0.047 14.1 2.2 0.52 10.7 0.1 2.8 1 1 2 3 3 3 0 Serine acetyltransferase, N-terminal DUF87 PF01935.17 EST43287.1 - 0.063 13.4 4.1 0.082 13.0 3.6 1.5 1 1 0 1 1 1 0 Helicase HerA, central domain Nuclease_act PF08133.11 EST43287.1 - 4.8 7.5 6.0 0.77 10.0 1.3 2.2 2 0 0 2 2 2 0 Anticodon nuclease activator family DDE_Tnp_1_4 PF13701.6 EST43288.1 - 0.17 10.2 0.0 0.22 9.7 0.0 1.1 1 0 0 1 1 1 0 Transposase DDE domain group 1 DUF1048 PF06304.11 EST43289.1 - 0.004 17.6 7.5 0.91 10.0 0.0 4.1 4 0 0 4 4 4 2 Protein of unknown function (DUF1048) Melibiase_2 PF16499.5 EST43290.1 - 6e-45 153.6 0.6 8.2e-45 153.2 0.6 1.1 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 EST43290.1 - 1.6e-11 44.1 0.4 3.3e-11 43.1 0.4 1.6 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase_2_C PF17450.2 EST43290.1 - 2.1e-07 31.1 0.0 1.7e-06 28.1 0.0 2.4 2 0 0 2 2 2 1 Alpha galactosidase A C-terminal beta sandwich domain Glyco_hydro_30C PF17189.4 EST43290.1 - 0.00022 21.4 0.7 0.0011 19.1 0.2 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 30 beta sandwich domain Melibiase PF02065.18 EST43290.1 - 0.001 18.1 0.0 0.0017 17.3 0.0 1.3 1 0 0 1 1 1 1 Melibiase PspC PF04024.12 EST43291.1 - 0.15 11.9 0.6 0.23 11.3 0.6 1.3 1 0 0 1 1 1 0 PspC domain SHIPPO-rpt PF07004.12 EST43292.1 - 1.5 9.9 27.9 1.7 9.7 0.2 5.0 4 2 0 4 4 4 0 Sperm-tail PG-rich repeat Topoisom_I_N PF02919.15 EST43295.1 - 0.026 14.0 1.3 0.032 13.7 1.3 1.0 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment DS PF01916.17 EST43296.1 - 1.5e-121 405.1 0.0 1.7e-121 404.9 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Peptidase_C1 PF00112.23 EST43298.1 - 3.7e-36 125.2 5.9 4.5e-36 125.0 5.9 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Cmc1 PF08583.10 EST43298.1 - 0.05 13.6 0.5 5.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like APG6_N PF17675.1 EST43299.1 - 0.28 11.7 5.3 4.2 7.9 0.3 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region SIS PF01380.22 EST43300.1 - 0.078 12.8 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 SIS domain Shikimate_DH PF01488.20 EST43300.1 - 0.16 12.1 1.5 0.27 11.3 0.7 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase SIR2_2 PF13289.6 EST43300.1 - 0.27 11.4 2.6 0.36 10.9 0.6 2.1 1 1 0 2 2 2 0 SIR2-like domain TPR_7 PF13176.6 EST43302.1 - 0.013 15.5 0.1 0.44 10.7 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EST43302.1 - 0.016 15.5 9.7 0.026 14.7 0.2 4.9 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EST43302.1 - 0.046 14.0 3.4 1.4 9.3 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 EST43302.1 - 0.057 14.3 0.1 1.9 9.5 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 EST43302.1 - 0.069 12.5 0.1 0.069 12.5 0.1 2.8 3 0 0 3 3 3 0 MalT-like TPR region TPR_1 PF00515.28 EST43302.1 - 0.12 12.3 1.1 32 4.6 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EST43302.1 - 0.12 12.6 0.8 1.9 8.9 0.2 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Xrn1_D3 PF18194.1 EST43303.1 - 0.058 13.5 0.2 1.6 8.9 0.0 2.4 2 0 0 2 2 2 0 Exoribonuclease 1 Domain-3 DUF719 PF05334.13 EST43303.1 - 0.12 12.6 0.5 0.15 12.2 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF719) DUF727 PF05303.12 EST43304.1 - 0.00021 21.3 1.7 0.0004 20.4 1.3 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF727) DUF4945 PF16303.5 EST43304.1 - 0.027 14.4 0.4 0.042 13.8 0.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4945) DUF3627 PF12299.8 EST43304.1 - 0.051 13.7 5.4 5.5 7.1 5.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3627) FTO_CTD PF12934.7 EST43305.1 - 0.034 13.9 0.2 0.045 13.5 0.2 1.2 1 0 0 1 1 1 0 FTO C-terminal domain HTH_3 PF01381.22 EST43306.1 - 4.4e-05 23.5 0.1 8.6e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_23 PF13384.6 EST43306.1 - 0.00078 19.2 0.1 0.0014 18.3 0.1 1.4 1 0 0 1 1 1 1 Homeodomain-like domain MIEAP PF16026.5 EST43306.1 - 0.018 15.3 0.9 0.021 15.1 0.9 1.2 1 0 0 1 1 1 0 Mitochondria-eating protein AvrM-A PF18241.1 EST43306.1 - 0.023 15.1 1.2 0.031 14.7 1.2 1.2 1 0 0 1 1 1 0 Flax-rust effector AvrM-A HTH_28 PF13518.6 EST43306.1 - 0.025 14.7 0.1 0.061 13.5 0.1 1.6 1 1 1 2 2 2 0 Helix-turn-helix domain BRCA-2_OB3 PF09104.10 EST43306.1 - 0.031 13.9 0.4 0.056 13.1 0.4 1.4 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 DUF3887 PF13026.6 EST43306.1 - 0.038 14.8 0.5 0.08 13.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3887) HTH_17 PF12728.7 EST43306.1 - 0.042 14.0 0.0 0.071 13.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Nmad5 PF18757.1 EST43306.1 - 0.056 13.6 0.1 0.1 12.8 0.0 1.4 1 1 0 1 1 1 0 Nucleotide modification associated domain 5 PemK_toxin PF02452.17 EST43306.1 - 0.073 13.5 0.2 0.11 12.8 0.2 1.4 1 0 0 1 1 1 0 PemK-like, MazF-like toxin of type II toxin-antitoxin system DUF134 PF02001.16 EST43306.1 - 0.095 13.3 0.1 0.24 12.0 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF134 DUF1192 PF06698.11 EST43306.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) HTH_ABP1_N PF18107.1 EST43306.1 - 0.57 9.9 5.0 0.33 10.7 0.3 2.5 2 1 0 2 2 2 0 Fission yeast centromere protein N-terminal domain Pre-PUA PF17832.1 EST43306.1 - 0.83 10.4 4.8 0.49 11.1 2.4 2.0 2 1 0 2 2 2 0 Pre-PUA-like domain His_Phos_1 PF00300.22 EST43307.1 - 3.8e-41 140.9 0.0 4.4e-41 140.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) HlyIII PF03006.20 EST43308.1 - 3.8e-14 52.9 4.3 4.5e-14 52.7 4.3 1.0 1 0 0 1 1 1 1 Haemolysin-III related Bac_export_2 PF01312.19 EST43308.1 - 0.02 14.1 0.2 0.023 13.9 0.2 1.0 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Ribosomal_L7Ae PF01248.26 EST43309.1 - 8.9e-13 47.8 0.0 1.1e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Pkinase PF00069.25 EST43310.1 - 1.6e-31 109.6 0.2 2.1e-31 109.2 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST43310.1 - 3.9e-14 52.6 0.0 6.1e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Fer4_19 PF06902.11 EST43310.1 - 0.16 12.1 0.0 0.39 10.8 0.0 1.6 1 0 0 1 1 1 0 Divergent 4Fe-4S mono-cluster PH_18 PF18469.1 EST43311.1 - 0.0069 16.4 0.1 0.0069 16.4 0.1 2.2 2 1 0 2 2 2 1 Pleckstrin homology domain MFS_1 PF07690.16 EST43312.1 - 7e-29 100.8 28.2 9.5e-29 100.4 28.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 EST43312.1 - 1.2e-08 33.9 35.7 4e-06 25.7 13.9 2.4 1 1 1 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.24 EST43312.1 - 3.3e-07 29.5 32.2 2.8e-05 23.2 16.4 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter HCMV_UL124 PF17609.2 EST43312.1 - 0.13 12.5 0.1 0.28 11.4 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function Ni_hydr_CYTB PF01292.20 EST43312.1 - 2.2 7.8 7.2 0.22 11.1 0.2 2.6 3 0 0 3 3 3 0 Prokaryotic cytochrome b561 DS PF01916.17 EST43313.1 - 2.2e-105 352.0 0.0 2.6e-105 351.8 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase DUF2180 PF09947.9 EST43313.1 - 0.11 12.5 0.4 0.33 10.9 0.2 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) Topoisom_I_N PF02919.15 EST43314.1 - 0.018 14.5 2.0 0.022 14.2 2.0 1.0 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Exo_endo_phos PF03372.23 EST43315.1 - 4.6e-07 29.6 0.8 1.8e-06 27.6 0.8 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Cofilin_ADF PF00241.20 EST43316.1 - 2.6e-30 104.7 0.4 2.9e-30 104.5 0.4 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein NAD_binding_3 PF03447.16 EST43317.1 - 0.073 13.7 0.1 0.38 11.4 0.0 2.3 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Abhydrolase_6 PF12697.7 EST43318.1 - 2.6e-12 47.8 0.0 3e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EST43318.1 - 1e-11 44.6 0.2 2.6e-11 43.3 0.2 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EST43318.1 - 2.9e-10 40.3 0.0 5.1e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 EST43318.1 - 1.2e-05 25.5 1.1 4.8e-05 23.6 0.1 1.9 1 1 1 2 2 2 1 Thioesterase domain Abhydrolase_5 PF12695.7 EST43318.1 - 0.0035 17.1 0.1 0.028 14.2 0.1 2.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 EST43318.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF900 PF05990.12 EST43318.1 - 0.11 11.9 0.6 0.39 10.2 0.7 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Chlorophyllase2 PF12740.7 EST43318.1 - 0.13 11.2 3.3 1.4 7.8 3.3 2.1 1 1 0 1 1 1 0 Chlorophyllase enzyme HIF-1 PF11413.8 EST43318.1 - 0.47 9.9 2.1 21 4.7 0.7 2.4 2 0 0 2 2 2 0 Hypoxia-inducible factor-1 HlyIII PF03006.20 EST43319.1 - 2e-29 102.9 23.1 2.3e-29 102.7 23.1 1.0 1 0 0 1 1 1 1 Haemolysin-III related ATP-synt_D PF01813.17 EST43320.1 - 7e-46 156.5 1.2 8.3e-46 156.3 1.2 1.1 1 0 0 1 1 1 1 ATP synthase subunit D Baculo_PEP_C PF04513.12 EST43320.1 - 0.014 15.4 0.5 0.064 13.3 0.1 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus 60KD_IMP PF02096.20 EST43320.1 - 0.073 13.0 0.4 0.18 11.7 0.4 1.6 1 0 0 1 1 1 0 60Kd inner membrane protein Surfac_D-trimer PF09006.11 EST43320.1 - 0.082 12.8 0.3 0.23 11.4 0.3 1.7 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation Snapin_Pallidin PF14712.6 EST43320.1 - 0.3 11.6 4.3 10 6.6 0.0 2.8 3 0 0 3 3 3 0 Snapin/Pallidin HlyIII PF03006.20 EST43321.1 - 1.4e-30 106.7 19.7 1.6e-30 106.5 19.7 1.0 1 0 0 1 1 1 1 Haemolysin-III related Bac_export_2 PF01312.19 EST43321.1 - 0.098 11.8 3.8 0.34 10.1 3.9 1.8 1 1 1 2 2 2 0 FlhB HrpN YscU SpaS Family Deltameth_res PF16020.5 EST43321.1 - 0.14 12.0 4.4 0.22 11.4 0.0 3.1 3 1 1 4 4 4 0 Deltamethrin resistance Sdh_cyt PF01127.22 EST43321.1 - 0.24 11.4 11.6 0.26 11.3 3.1 2.7 1 1 1 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF3522 PF12036.8 EST43321.1 - 0.24 11.7 10.3 0.39 11.0 10.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3522) Rad60-SLD PF11976.8 EST43322.1 - 4.9e-13 48.7 1.4 6.6e-13 48.3 1.2 1.3 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EST43322.1 - 5.3e-08 32.5 0.7 6.6e-08 32.2 0.7 1.1 1 0 0 1 1 1 1 Ubiquitin family RE_SinI PF09570.10 EST43322.1 - 0.025 13.8 0.0 0.03 13.6 0.0 1.1 1 0 0 1 1 1 0 SinI restriction endonuclease FTR PF01913.18 EST43322.1 - 0.035 14.1 0.1 0.04 13.8 0.1 1.1 1 0 0 1 1 1 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase Sec16 PF12932.7 EST43323.1 - 0.086 13.4 0.0 0.095 13.3 0.0 1.1 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region La PF05383.17 EST43327.1 - 0.097 12.7 0.0 0.28 11.2 0.0 1.9 1 0 0 1 1 1 0 La domain Zn_Tnp_IS91 PF14319.6 EST43327.1 - 0.1 12.6 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Transposase zinc-binding domain Ank_2 PF12796.7 EST43328.1 - 7.1e-08 32.9 3.1 0.0048 17.5 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EST43328.1 - 0.00033 21.0 0.0 7.4 7.2 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 EST43328.1 - 0.0019 18.6 1.9 17 6.4 0.1 4.6 3 1 1 4 4 4 2 Ankyrin repeat Phage_holin_3_6 PF07332.11 EST43329.1 - 0.14 12.2 0.2 0.22 11.6 0.2 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III ATP-synt_C PF00137.21 EST43330.1 - 2.7e-29 101.3 37.3 1.3e-17 63.9 14.7 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DnaJ PF00226.31 EST43333.1 - 9.3e-19 67.3 8.1 7.6e-18 64.4 5.2 3.3 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_2 PF12756.7 EST43333.1 - 2.5e-05 24.5 9.3 0.016 15.5 0.2 3.6 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EST43333.1 - 7e-05 23.3 5.0 0.18 12.8 0.4 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 EST43333.1 - 0.0017 18.7 4.4 0.14 12.6 0.6 2.9 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 EST43333.1 - 0.013 15.8 0.4 8.1 6.8 0.1 2.7 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-met2 PF12907.7 EST43333.1 - 0.02 15.0 2.4 5.9 7.1 0.4 2.7 2 0 0 2 2 2 0 Zinc-binding zf-C2H2 PF00096.26 EST43333.1 - 0.075 13.5 9.8 0.34 11.5 0.6 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-DBF PF07535.12 EST43333.1 - 0.1 12.7 3.1 0.18 12.0 0.3 2.4 2 0 0 2 2 2 0 DBF zinc finger U5_2-snRNA_bdg PF10597.9 EST43333.1 - 0.35 10.9 2.0 0.47 10.5 0.0 2.2 3 0 0 3 3 3 0 U5-snRNA binding site 2 of PrP8 zf-C2H2_6 PF13912.6 EST43333.1 - 9 6.4 7.4 5.9 7.0 1.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger HTH_23 PF13384.6 EST43336.1 - 2.3e-07 30.4 0.3 0.00057 19.6 0.1 2.2 2 0 0 2 2 2 2 Homeodomain-like domain HTH_29 PF13551.6 EST43336.1 - 3.4e-06 27.0 0.2 5.1e-05 23.2 0.1 2.1 2 0 0 2 2 2 1 Winged helix-turn helix HTH_38 PF13936.6 EST43336.1 - 3.7e-06 26.6 5.1 0.0014 18.3 0.2 2.5 2 1 0 2 2 2 2 Helix-turn-helix domain PAX PF00292.18 EST43336.1 - 3.8e-05 23.6 0.2 0.00011 22.2 0.2 1.6 1 1 1 2 2 2 1 'Paired box' domain HTH_7 PF02796.15 EST43336.1 - 0.00088 19.3 2.2 0.091 12.9 0.3 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 EST43336.1 - 0.0068 16.5 0.2 0.1 12.7 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_40 PF14493.6 EST43336.1 - 0.022 15.2 0.5 0.69 10.4 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 EST43336.1 - 0.071 12.5 0.0 2.7 7.5 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_32 PF13565.6 EST43336.1 - 0.079 13.6 0.0 0.24 12.1 0.0 1.8 1 1 1 2 2 2 0 Homeodomain-like domain MerR_1 PF13411.6 EST43336.1 - 0.14 12.2 2.0 0.2 11.8 0.3 2.1 2 1 0 2 2 2 0 MerR HTH family regulatory protein MIF PF01187.18 EST43337.1 - 6.5e-23 81.2 0.0 7.1e-23 81.1 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.21 EST43337.1 - 1e-05 25.4 0.0 0.0039 17.1 0.0 2.1 2 0 0 2 2 2 2 Tautomerase enzyme DUF1904 PF08921.11 EST43337.1 - 0.0015 18.8 0.0 0.0017 18.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1904) Tautomerase_2 PF14552.6 EST43337.1 - 0.0023 18.0 0.0 0.0049 16.9 0.0 1.5 2 0 0 2 2 2 1 Tautomerase enzyme RabGAP-TBC PF00566.18 EST43338.1 - 1.3e-11 44.6 13.9 2.6e-11 43.6 13.9 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Cep57_CLD_2 PF14197.6 EST43339.1 - 0.049 13.7 0.3 0.049 13.7 0.3 3.2 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 OmpH PF03938.14 EST43339.1 - 0.18 12.1 7.9 0.79 10.1 7.9 2.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FliD_N PF02465.18 EST43339.1 - 1.1 10.0 6.6 2.2 9.0 4.7 2.7 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF4404 PF14357.6 EST43339.1 - 1.6 9.4 9.2 0.26 12.0 1.0 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4404) Exonuc_VII_L PF02601.15 EST43339.1 - 2.9 7.4 10.4 0.26 10.8 4.4 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit SBDS PF01172.18 EST43342.1 - 3.6e-23 81.5 0.8 3.6e-23 81.5 0.8 2.1 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 EST43342.1 - 2.8e-09 37.0 2.3 2.8e-09 37.0 2.3 1.6 2 0 0 2 2 2 1 SBDS protein C-terminal domain Dala_Dala_lig_N PF01820.21 EST43342.1 - 0.29 11.6 1.4 0.8 10.2 0.0 2.2 2 1 0 2 2 2 0 D-ala D-ala ligase N-terminus Pkinase PF00069.25 EST43346.1 - 1.8e-25 89.8 1.1 5e-25 88.4 1.1 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST43346.1 - 3.5e-08 33.0 0.1 1.6e-07 30.9 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EST43346.1 - 3.5e-05 22.9 1.1 0.00018 20.6 0.1 2.1 2 0 0 2 2 2 1 Haspin like kinase domain Choline_kinase PF01633.20 EST43346.1 - 0.0009 18.9 0.2 0.0021 17.7 0.2 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 EST43346.1 - 0.011 15.0 0.2 0.026 13.9 0.2 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HEPN_RiboL-PSP PF18735.1 EST43346.1 - 0.062 13.2 1.5 0.16 11.9 1.5 1.7 1 0 0 1 1 1 0 RiboL-PSP-HEPN APH PF01636.23 EST43346.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-CCCH PF00642.24 EST43347.1 - 0.016 15.1 1.2 0.016 15.1 1.2 3.6 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 EST43347.1 - 0.54 10.5 14.2 1.3 9.2 14.2 1.7 1 1 0 1 1 1 0 Zinc-finger containing family 5_nucleotid PF05761.14 EST43348.1 - 9.3e-37 127.0 2.3 1.1e-36 126.8 2.3 1.0 1 0 0 1 1 1 1 5' nucleotidase family ABC_tran_CTD PF16326.5 EST43348.1 - 0.0019 18.4 3.8 0.0059 16.8 3.8 1.8 1 0 0 1 1 1 1 ABC transporter C-terminal domain DUF2096 PF09869.9 EST43348.1 - 0.021 14.9 0.5 0.04 14.0 0.1 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2096) AAA_lid_9 PF17871.1 EST43348.1 - 0.026 14.5 2.0 4.9 7.1 0.0 3.0 3 1 0 3 3 3 0 AAA lid domain Palm_thioest PF02089.15 EST43351.1 - 1.2e-59 202.1 0.1 1.5e-59 201.7 0.1 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 EST43351.1 - 6e-08 32.5 0.0 9.4e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF915 PF06028.11 EST43351.1 - 3.4e-05 23.3 0.0 0.037 13.4 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.13 EST43351.1 - 7.3e-05 22.6 0.3 0.00095 18.9 0.0 2.4 2 1 0 2 2 2 1 PGAP1-like protein Abhydrolase_1 PF00561.20 EST43351.1 - 0.0001 22.0 0.2 0.00028 20.6 0.2 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Glycophorin_A PF01102.18 EST43351.1 - 0.00085 19.5 0.5 0.0015 18.8 0.5 1.3 1 0 0 1 1 1 1 Glycophorin A Abhydrolase_6 PF12697.7 EST43351.1 - 0.0018 18.9 0.0 0.0025 18.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EST43351.1 - 0.0022 17.3 0.0 0.0081 15.4 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF3147 PF11345.8 EST43351.1 - 0.0051 17.2 0.6 0.0095 16.3 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3147) Lipase_2 PF01674.18 EST43351.1 - 0.011 15.2 0.1 0.077 12.5 0.1 2.1 1 1 0 1 1 1 0 Lipase (class 2) Rax2 PF12768.7 EST43351.1 - 0.027 13.9 1.1 0.046 13.2 1.1 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Lipase_3 PF01764.25 EST43351.1 - 0.046 13.6 0.3 0.19 11.6 0.0 2.1 2 1 0 2 2 2 0 Lipase (class 3) DUF4690 PF15756.5 EST43351.1 - 0.18 12.4 0.1 0.36 11.5 0.1 1.4 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Palm_thioest PF02089.15 EST43352.1 - 6e-52 176.9 0.2 8.9e-52 176.3 0.2 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 EST43352.1 - 1.5e-05 24.9 0.0 2.9e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 PGAP1-like protein Glycophorin_A PF01102.18 EST43352.1 - 0.00087 19.5 0.6 0.0016 18.7 0.6 1.4 1 0 0 1 1 1 1 Glycophorin A DUF676 PF05057.14 EST43352.1 - 0.013 15.0 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 EST43352.1 - 0.053 12.8 0.0 0.094 12.0 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Lipase_3 PF01764.25 EST43352.1 - 0.069 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Myb_DNA-bind_6 PF13921.6 EST43353.1 - 5.2e-08 33.0 0.1 7.1e-08 32.6 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EST43353.1 - 1.9e-07 31.1 0.0 2.8e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain HTH_Tnp_Tc3_1 PF11427.8 EST43353.1 - 0.097 12.5 0.0 0.29 11.0 0.0 1.7 2 0 0 2 2 2 0 Tc3 transposase Phenol_monoox PF04663.12 EST43354.1 - 0.072 13.2 0.1 0.33 11.1 0.1 2.2 1 0 0 1 1 1 0 Phenol hydroxylase conserved region DUF1968 PF09291.10 EST43356.1 - 0.033 14.3 2.5 0.085 12.9 2.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1968) PRKG1_interact PF15898.5 EST43356.1 - 0.045 14.6 0.4 0.045 14.6 0.4 2.7 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain 5_nucleotid PF05761.14 EST43357.1 - 1.1e-68 232.2 10.5 1.3e-68 232.0 10.5 1.0 1 0 0 1 1 1 1 5' nucleotidase family ABC_tran_CTD PF16326.5 EST43357.1 - 0.0036 17.5 3.9 0.012 15.8 3.9 1.9 1 0 0 1 1 1 1 ABC transporter C-terminal domain DUF2096 PF09869.9 EST43357.1 - 0.031 14.3 0.1 0.08 13.0 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) AAA_lid_9 PF17871.1 EST43357.1 - 0.076 13.0 2.1 8.5 6.4 0.0 3.2 3 0 0 3 3 3 0 AAA lid domain Spc7_C2 PF15577.6 EST43359.1 - 0.0036 17.4 0.1 0.73 10.0 0.0 2.7 2 0 0 2 2 2 2 Spc7_C2 Palm_thioest PF02089.15 EST43360.1 - 1.4e-58 198.6 0.1 1.7e-58 198.3 0.1 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 EST43360.1 - 2.3e-08 33.8 0.0 3.6e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 EST43360.1 - 7.4e-06 25.9 0.1 0.00025 20.8 0.0 2.2 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_1 PF00561.20 EST43360.1 - 0.0015 18.2 0.2 0.0032 17.2 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EST43360.1 - 0.0047 17.5 0.0 0.01 16.5 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.11 EST43360.1 - 0.0084 15.5 0.2 0.046 13.1 0.1 2.0 1 1 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.25 EST43360.1 - 0.012 15.4 0.6 0.04 13.8 0.1 1.9 2 0 0 2 2 2 0 Lipase (class 3) Rax2 PF12768.7 EST43360.1 - 0.028 13.9 0.3 0.048 13.1 0.3 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Lipase_2 PF01674.18 EST43360.1 - 0.042 13.4 0.0 0.081 12.4 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 2) SMC_N PF02463.19 EST43360.1 - 0.056 12.9 0.1 0.089 12.2 0.1 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain DUF4448 PF14610.6 EST43360.1 - 0.08 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) LCAT PF02450.15 EST43360.1 - 0.13 11.4 1.6 0.18 11.0 0.6 2.0 2 1 0 2 2 2 0 Lecithin:cholesterol acyltransferase AAA PF00004.29 EST43365.1 - 6.5e-34 117.2 0.2 1.9e-23 83.4 0.2 3.2 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EST43365.1 - 1.1e-08 35.7 0.0 0.0026 18.1 0.0 3.4 3 0 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 EST43365.1 - 2.5e-07 30.3 0.2 0.0033 17.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 EST43365.1 - 1.4e-06 28.9 0.5 0.11 13.0 0.2 3.2 2 1 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 EST43365.1 - 2.5e-06 27.6 0.1 0.009 15.9 0.0 2.4 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EST43365.1 - 4.1e-06 27.1 0.3 0.0011 19.3 0.1 3.2 2 2 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EST43365.1 - 8e-06 25.5 0.2 0.015 14.9 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region T2SSE PF00437.20 EST43365.1 - 2e-05 23.8 0.1 0.11 11.5 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_14 PF13173.6 EST43365.1 - 2.7e-05 24.2 0.1 0.19 11.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.18 EST43365.1 - 2.8e-05 23.6 0.0 0.0031 16.9 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family NACHT PF05729.12 EST43365.1 - 4.6e-05 23.4 0.1 0.068 13.1 0.1 3.1 2 1 1 3 3 3 1 NACHT domain PduV-EutP PF10662.9 EST43365.1 - 0.00016 21.4 0.1 0.28 10.9 0.1 2.5 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 EST43365.1 - 0.00022 21.5 0.5 0.29 11.4 0.7 2.9 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EST43365.1 - 0.00025 21.6 1.8 0.052 14.1 0.0 2.9 2 1 0 2 2 2 1 ABC transporter Pox_A32 PF04665.12 EST43365.1 - 0.00026 20.5 2.6 0.19 11.2 0.4 3.1 2 1 1 3 3 3 2 Poxvirus A32 protein AAA_24 PF13479.6 EST43365.1 - 0.00034 20.4 0.0 0.018 14.8 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 EST43365.1 - 0.00038 20.1 0.5 3.2 7.3 0.3 3.2 2 1 1 3 3 3 1 AAA domain Rad17 PF03215.15 EST43365.1 - 0.00072 19.5 0.4 0.29 11.1 0.1 2.5 2 1 0 2 2 2 1 Rad17 P-loop domain SRPRB PF09439.10 EST43365.1 - 0.00075 19.0 0.1 0.98 8.8 0.0 2.5 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit TsaE PF02367.17 EST43365.1 - 0.00084 19.3 0.0 0.55 10.2 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 EST43365.1 - 0.0011 18.9 0.7 0.33 10.9 0.4 3.8 2 2 1 3 3 2 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 EST43365.1 - 0.0014 19.2 7.1 0.016 15.7 0.2 3.1 3 1 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 EST43365.1 - 0.0016 18.8 0.0 0.73 10.2 0.0 2.6 2 0 0 2 2 2 1 RNA helicase TniB PF05621.11 EST43365.1 - 0.0016 17.8 0.0 0.064 12.7 0.0 2.5 2 0 0 2 2 2 1 Bacterial TniB protein MobB PF03205.14 EST43365.1 - 0.0017 18.3 0.5 0.19 11.6 0.1 2.8 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 EST43365.1 - 0.0025 18.0 0.0 0.068 13.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EST43365.1 - 0.0036 17.6 0.1 0.05 13.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain Septin PF00735.18 EST43365.1 - 0.0046 16.3 0.4 0.22 10.8 0.1 2.3 2 0 0 2 2 2 1 Septin TIP49 PF06068.13 EST43365.1 - 0.0051 16.1 0.0 2.6 7.1 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain RsgA_GTPase PF03193.16 EST43365.1 - 0.0053 16.7 0.1 0.18 11.7 0.1 2.9 2 1 1 3 3 3 1 RsgA GTPase NTPase_1 PF03266.15 EST43365.1 - 0.0057 16.6 0.1 1.3 8.9 0.1 2.5 2 0 0 2 2 2 1 NTPase G-alpha PF00503.20 EST43365.1 - 0.0059 15.8 2.7 0.41 9.8 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit cobW PF02492.19 EST43365.1 - 0.0085 15.7 0.2 0.38 10.3 0.2 2.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 EST43365.1 - 0.0092 16.2 0.2 1.4 9.2 0.1 3.0 2 1 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase TrwB_AAD_bind PF10412.9 EST43365.1 - 0.0098 14.8 0.0 0.047 12.6 0.0 2.1 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain RuvB_N PF05496.12 EST43365.1 - 0.011 15.5 0.0 3.6 7.3 0.0 2.6 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain dNK PF01712.19 EST43365.1 - 0.015 15.1 0.8 0.7 9.7 0.0 2.4 2 1 0 2 2 2 0 Deoxynucleoside kinase CbiA PF01656.23 EST43365.1 - 0.016 15.2 0.0 1.7 8.7 0.0 2.5 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.22 EST43365.1 - 0.028 14.1 0.2 2.2 7.8 0.1 2.9 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain PRK PF00485.18 EST43365.1 - 0.029 14.1 0.1 0.48 10.1 0.0 2.6 2 1 1 3 3 3 0 Phosphoribulokinase / Uridine kinase family DUF815 PF05673.13 EST43365.1 - 0.032 13.4 0.1 0.098 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_32 PF13654.6 EST43365.1 - 0.034 13.0 0.1 3.9 6.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EST43365.1 - 0.035 13.9 0.0 4.5 7.0 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_11 PF13086.6 EST43365.1 - 0.037 13.8 0.0 8.7 6.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EST43365.1 - 0.037 13.8 0.0 0.096 12.4 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase PF06745.13 EST43365.1 - 0.044 13.1 1.2 0.42 9.9 0.0 3.0 5 0 0 5 5 3 0 KaiC SMC_N PF02463.19 EST43365.1 - 0.05 13.0 0.1 1.2 8.5 0.0 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain DLIC PF05783.11 EST43365.1 - 0.052 12.4 0.0 0.57 8.9 0.0 2.0 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) PglD_N PF17836.1 EST43365.1 - 0.061 14.0 0.0 7.2 7.3 0.0 2.6 2 0 0 2 2 2 0 PglD N-terminal domain Zeta_toxin PF06414.12 EST43365.1 - 0.062 12.6 0.0 0.58 9.4 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin Arf PF00025.21 EST43365.1 - 0.07 12.6 1.8 17 4.8 0.0 3.5 4 0 0 4 4 4 0 ADP-ribosylation factor family ATP_bind_1 PF03029.17 EST43365.1 - 0.083 12.7 0.6 2.8 7.7 0.1 2.8 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 EST43365.1 - 0.088 12.0 0.0 0.47 9.6 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain GTP_EFTU PF00009.27 EST43365.1 - 0.15 11.6 0.5 6.2 6.3 0.1 3.0 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EST43365.1 - 0.17 12.0 3.3 3.2 7.9 0.2 2.9 2 2 0 2 2 2 0 50S ribosome-binding GTPase Band_7 PF01145.25 EST43366.1 - 3.6e-24 85.7 0.1 3.6e-24 85.7 0.1 1.5 2 0 0 2 2 2 1 SPFH domain / Band 7 family Tox-PL-2 PF15643.6 EST43366.1 - 0.15 12.2 2.3 9 6.5 0.3 2.8 3 0 0 3 3 3 0 Papain fold toxin 2 DUF735 PF05246.11 EST43367.1 - 0.031 14.2 1.8 0.033 14.2 1.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF735) AAA_7 PF12775.7 EST43367.1 - 0.06 12.9 0.4 0.081 12.4 0.4 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 EST43369.1 - 3e-84 280.0 0.0 1.8e-16 60.4 0.0 9.6 8 1 0 8 8 8 7 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EST43369.1 - 1.2e-29 102.8 0.0 2.1e-10 40.5 0.0 7.5 7 0 0 7 7 7 4 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 EST43369.1 - 3.6e-24 84.9 1.6 1.7e-23 82.7 0.8 2.8 2 0 0 2 2 1 1 Midasin AAA lid domain AAA PF00004.29 EST43369.1 - 3.9e-14 53.2 5.4 0.012 16.1 0.0 7.6 6 0 0 6 6 6 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EST43369.1 - 1.1e-13 51.9 4.8 0.068 13.6 0.0 7.2 7 0 0 7 7 6 4 AAA ATPase domain AAA_7 PF12775.7 EST43369.1 - 9.8e-12 44.7 0.7 0.97 8.9 0.1 6.2 5 0 0 5 5 5 3 P-loop containing dynein motor region Mg_chelatase PF01078.21 EST43369.1 - 1.1e-11 44.5 1.4 0.013 14.9 0.0 7.6 8 0 0 8 8 8 1 Magnesium chelatase, subunit ChlI Dynein_heavy PF03028.15 EST43369.1 - 1.4e-11 44.5 0.6 0.011 15.9 0.0 5.9 5 0 0 5 5 5 2 Dynein heavy chain region D6 P-loop domain AAA_lid_7 PF17867.1 EST43369.1 - 2.2e-11 43.9 7.2 0.00012 22.2 0.1 6.1 5 0 0 5 5 5 2 Midasin AAA lid domain VWA_2 PF13519.6 EST43369.1 - 3.8e-09 37.2 0.2 6e-08 33.3 0.5 3.1 2 0 0 2 2 1 1 von Willebrand factor type A domain AAA_6 PF12774.7 EST43369.1 - 3.4e-08 32.8 27.8 0.028 13.4 0.0 8.7 8 1 0 8 8 7 4 Hydrolytic ATP binding site of dynein motor region IstB_IS21 PF01695.17 EST43369.1 - 1.4e-07 31.4 0.4 1.3 8.7 0.0 5.2 5 0 0 5 5 5 2 IstB-like ATP binding protein AAA_22 PF13401.6 EST43369.1 - 1.5e-07 31.8 1.8 2.2 8.6 0.0 7.1 5 1 0 5 5 5 1 AAA domain AAA_18 PF13238.6 EST43369.1 - 1.8e-07 31.7 10.2 0.44 11.1 0.0 6.8 7 0 0 7 7 4 2 AAA domain AAA_19 PF13245.6 EST43369.1 - 6.9e-07 29.7 0.2 2.3 8.6 0.0 5.5 4 1 0 4 4 4 1 AAA domain TsaE PF02367.17 EST43369.1 - 7.9e-07 29.1 1.1 13 5.8 0.0 6.2 7 0 0 7 7 6 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 EST43369.1 - 1.2e-06 27.8 1.2 0.15 11.1 0.0 4.3 4 0 0 4 4 4 2 Type II/IV secretion system protein AAA_30 PF13604.6 EST43369.1 - 2.4e-06 27.4 0.0 5.2 6.8 0.0 5.8 5 2 0 5 5 5 1 AAA domain Sigma54_activat PF00158.26 EST43369.1 - 3.1e-06 27.0 0.1 0.075 12.7 0.0 6.0 6 0 0 6 6 6 1 Sigma-54 interaction domain AAA_33 PF13671.6 EST43369.1 - 3.7e-06 27.1 0.0 0.83 9.8 0.0 4.8 4 0 0 4 4 4 1 AAA domain RuvB_N PF05496.12 EST43369.1 - 2.4e-05 24.1 1.6 3.6 7.3 0.0 5.3 5 0 0 5 5 5 1 Holliday junction DNA helicase RuvB P-loop domain RsgA_GTPase PF03193.16 EST43369.1 - 0.00082 19.3 3.2 7.6 6.4 0.5 5.5 5 0 0 5 5 4 0 RsgA GTPase CPT PF07931.12 EST43369.1 - 0.0012 18.7 0.6 5.2 6.9 0.0 5.3 7 0 0 7 7 6 1 Chloramphenicol phosphotransferase-like protein NACHT PF05729.12 EST43369.1 - 0.0013 18.7 0.1 5.4 6.9 0.0 4.5 4 0 0 4 4 3 1 NACHT domain AAA_28 PF13521.6 EST43369.1 - 0.0032 17.7 3.1 2.9 8.1 0.0 4.3 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.22 EST43369.1 - 0.004 17.5 0.0 9.9 6.6 0.0 5.1 4 0 0 4 4 4 0 RNA helicase AAA_29 PF13555.6 EST43369.1 - 0.0074 16.0 0.1 11 5.9 0.0 4.0 3 0 0 3 3 3 0 P-loop containing region of AAA domain VWA_CoxE PF05762.14 EST43369.1 - 0.0076 15.7 0.0 0.025 14.0 0.0 1.8 2 0 0 2 2 1 1 VWA domain containing CoxE-like protein Sigma54_activ_2 PF14532.6 EST43369.1 - 0.0087 16.2 7.1 3 8.0 0.0 6.3 7 0 0 7 7 6 1 Sigma-54 interaction domain Viral_helicase1 PF01443.18 EST43369.1 - 0.0096 15.7 0.0 0.66 9.7 0.0 3.6 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 EST43369.1 - 0.21 12.1 0.0 0.21 12.1 0.0 8.1 8 1 0 8 8 6 0 ABC transporter HALZ PF02183.18 EST43370.1 - 0.014 15.6 3.7 1.7 9.0 0.5 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper DegS PF05384.11 EST43370.1 - 0.021 14.3 2.4 0.036 13.6 2.4 1.3 1 0 0 1 1 1 0 Sensor protein DegS ZapB PF06005.12 EST43370.1 - 0.045 14.2 4.5 0.1 13.1 4.5 1.5 1 0 0 1 1 1 0 Cell division protein ZapB DUF3567 PF12091.8 EST43370.1 - 0.092 12.9 0.2 0.38 10.9 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3567) DivIC PF04977.15 EST43370.1 - 0.11 12.2 3.0 0.25 11.2 3.0 1.6 1 0 0 1 1 1 0 Septum formation initiator Acyltransferase PF01553.21 EST43371.1 - 1.9e-08 34.0 0.1 3.2e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 Acyltransferase RRM_5 PF13893.6 EST43372.1 - 0.037 13.6 0.0 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 EST43372.1 - 0.068 13.0 0.0 0.49 10.3 0.0 2.1 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4315 PF14193.6 EST43372.1 - 0.35 10.9 4.9 0.12 12.4 1.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) EzrA PF06160.12 EST43373.1 - 0.00027 19.2 6.9 0.00027 19.2 6.9 1.4 2 0 0 2 2 2 1 Septation ring formation regulator, EzrA Glyco_hydro_30 PF02055.16 EST43373.1 - 0.031 13.3 0.1 0.042 12.8 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 30 TIM-barrel domain Atg14 PF10186.9 EST43373.1 - 0.081 12.0 12.5 0.15 11.2 12.5 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 AATF-Che1 PF13339.6 EST43373.1 - 1.7 9.3 16.3 7.1 7.3 7.5 2.3 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor LMBR1 PF04791.16 EST43373.1 - 4.6 6.0 5.7 5.1 5.9 5.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4407 PF14362.6 EST43373.1 - 5 6.4 13.9 8.6 5.6 13.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Colicin_K PF17500.2 EST43374.1 - 1.4e-08 35.2 2.7 5.3 7.7 0.0 6.5 7 0 0 7 7 7 4 Colicin-K DUF3631 PF12307.8 EST43374.1 - 9.6e-05 22.7 6.0 31 4.7 0.0 5.3 5 0 0 5 5 5 0 Protein of unknown function (DUF3631) DUF5442 PF17514.2 EST43374.1 - 0.0038 17.4 8.8 5.4 7.3 0.0 5.1 5 0 0 5 5 5 2 Family of unknown function (DUF5442) PRE_C2HC PF07530.11 EST43374.1 - 0.0093 16.1 0.2 65 3.7 0.0 3.8 3 0 0 3 3 3 0 Associated with zinc fingers DUF3069 PF11269.8 EST43374.1 - 0.01 16.1 7.8 26 5.1 0.1 5.4 5 0 0 5 5 5 0 Protein of unknown function (DUF3069) FliW PF02623.15 EST43374.1 - 0.047 13.6 8.2 23 4.9 0.2 4.6 4 0 0 4 4 4 0 FliW protein UBA_6 PF18039.1 EST43374.1 - 0.86 9.6 12.2 89 3.1 0.1 5.6 5 0 0 5 5 5 0 UBA-like domain DUF983 PF06170.12 EST43375.1 - 1.7 9.1 8.0 3.5 8.1 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF983) DSHCT PF08148.12 EST43377.1 - 1.1e-25 90.1 0.3 2.8e-25 88.9 0.3 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 EST43377.1 - 8.9e-20 71.2 0.1 1.9e-19 70.1 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.6 EST43377.1 - 8e-07 29.3 0.0 4.5e-06 26.8 0.0 2.1 1 1 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.31 EST43377.1 - 1.3e-06 28.7 0.1 2.1e-05 24.8 0.1 2.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EST43377.1 - 0.046 14.0 0.0 0.32 11.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain UPF0181 PF03701.14 EST43377.1 - 0.13 11.9 1.3 1.2 8.8 0.2 2.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0181) EamA PF00892.20 EST43378.1 - 0.00047 20.3 29.1 0.0012 19.0 9.8 3.2 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 EST43378.1 - 0.25 10.5 19.9 0.49 9.6 19.6 1.7 1 1 1 2 2 2 0 Purine nucleobase transmembrane transport SLC35F PF06027.12 EST43378.1 - 1.6 8.2 22.2 1.9 7.9 16.8 2.5 2 1 0 2 2 2 0 Solute carrier family 35 DUF5448 PF17526.2 EST43379.1 - 0.13 12.4 0.0 0.33 11.1 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5448) CAGE1 PF15066.6 EST43380.1 - 0.0078 14.9 0.4 0.0097 14.6 0.4 1.1 1 0 0 1 1 1 1 Cancer-associated gene protein 1 family Ras PF00071.22 EST43381.1 - 4.1e-30 104.5 0.0 4.7e-30 104.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EST43381.1 - 2e-17 63.5 0.0 2.7e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EST43381.1 - 5.3e-13 48.8 0.0 7e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EST43381.1 - 3.1e-06 26.7 0.0 3.6e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EST43381.1 - 0.00026 21.1 0.0 0.00035 20.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EST43381.1 - 0.037 13.9 0.0 0.34 10.8 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase DUF1122 PF06557.11 EST43381.1 - 0.057 12.9 0.0 0.089 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1122) FeoB_N PF02421.18 EST43381.1 - 0.13 11.8 0.0 0.44 10.1 0.0 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B TniB PF05621.11 EST43381.1 - 0.19 11.1 0.0 0.59 9.5 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein DUF3509 PF12021.8 EST43383.1 - 0.05 13.4 1.9 0.18 11.6 1.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3509) DUF61 PF01886.16 EST43383.1 - 0.26 11.3 5.5 1.4 8.9 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function DUF61 DUF1664 PF07889.12 EST43383.1 - 1 9.4 12.9 1.4 8.9 2.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) AAA_9 PF12781.7 EST43383.1 - 7 5.7 13.0 5.6 6.0 4.3 2.3 2 0 0 2 2 2 0 ATP-binding dynein motor region PAP_assoc PF03828.19 EST43384.1 - 5.2e-05 23.4 0.4 0.00014 22.0 0.4 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EST43384.1 - 0.0068 16.7 0.0 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EST43384.1 - 0.03 14.4 0.2 0.11 12.6 0.2 2.1 1 1 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase ydhR PF08803.11 EST43384.1 - 0.13 12.2 0.0 2.1 8.3 0.0 2.5 2 0 0 2 2 2 0 Putative mono-oxygenase ydhR Pkinase PF00069.25 EST43385.1 - 3.2e-30 105.4 2.0 2.4e-29 102.5 2.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST43385.1 - 7.3e-08 32.0 1.2 3e-06 26.7 0.3 2.9 2 1 0 2 2 2 1 Protein tyrosine kinase LRR_4 PF12799.7 EST43386.1 - 0.0066 16.8 0.0 8.4 7.0 0.0 4.2 5 1 0 5 5 5 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EST43386.1 - 0.012 15.3 1.2 7.6 6.4 0.0 3.8 3 0 0 3 3 3 0 Leucine rich repeat Aldedh PF00171.22 EST43388.1 - 9.7e-58 195.8 0.0 1.5e-57 195.1 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF5097 PF17020.5 EST43388.1 - 0.047 14.0 1.1 0.1 12.9 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5097) CCSMST1 PF15013.6 EST43396.1 - 0.18 12.0 1.7 0.24 11.6 0.3 2.1 1 1 1 2 2 2 0 CCSMST1 family VSP PF03302.13 EST43399.1 - 1.2e-13 50.7 268.6 0.0017 17.3 26.1 10.2 1 1 8 9 9 9 7 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST43399.1 - 0.0056 16.8 20.0 0.0056 16.8 20.0 11.0 1 1 10 11 11 11 1 Furin-like repeat, cysteine-rich DUF3979 PF13141.6 EST43400.1 - 3 8.1 11.6 0.93 9.8 1.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3979) VSP PF03302.13 EST43401.1 - 2e-05 23.6 202.0 0.0034 16.3 46.1 7.3 1 1 5 6 6 6 5 Giardia variant-specific surface protein VSP PF03302.13 EST43404.1 - 6.6e-16 58.1 139.3 2.4e-05 23.4 18.2 6.1 1 1 5 6 6 6 5 Giardia variant-specific surface protein VSP PF03302.13 EST43406.1 - 1.1e-14 54.1 145.0 4.2e-05 22.6 22.7 6.9 1 1 6 7 7 7 5 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST43406.1 - 0.016 15.3 140.6 0.18 12.0 11.4 8.0 1 1 6 7 7 7 0 Furin-like repeat, cysteine-rich Mid2 PF04478.12 EST43406.1 - 0.062 13.1 1.6 0.11 12.4 1.6 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Podoplanin PF05808.11 EST43406.1 - 0.1 12.7 0.2 0.16 12.1 0.2 1.3 1 0 0 1 1 1 0 Podoplanin ArAE_2_N PF10337.9 EST43406.1 - 0.31 10.0 1.7 0.39 9.7 1.7 1.1 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal VSP PF03302.13 EST43409.1 - 8.4e-12 44.6 136.7 0.00064 18.7 32.7 6.2 1 1 5 6 6 6 5 Giardia variant-specific surface protein DUF4366 PF14283.6 EST43409.1 - 0.037 14.1 0.2 0.12 12.4 0.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) E2F_TDP PF02319.20 EST43412.1 - 0.59 10.2 5.2 17 5.5 5.1 2.9 1 1 0 1 1 1 0 E2F/DP family winged-helix DNA-binding domain C9orf72-like PF15019.6 EST43413.1 - 0.0055 16.3 1.5 0.01 15.4 1.5 1.4 1 0 0 1 1 1 1 C9orf72-like protein family UNC45-central PF11701.8 EST43413.1 - 0.023 14.6 0.5 0.039 13.9 0.2 1.6 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central DUF4790 PF16037.5 EST43414.1 - 0.0034 17.8 1.5 0.0034 17.8 1.5 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4790) Ski2_N PF17911.1 EST43414.1 - 0.087 12.6 0.4 0.2 11.4 0.1 1.7 2 0 0 2 2 2 0 Ski2 N-terminal region Glyco_transf_43 PF03360.16 EST43414.1 - 0.11 12.2 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase family 43 POT1 PF02765.17 EST43415.1 - 0.0059 16.4 0.1 0.0075 16.1 0.1 1.2 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Peptidase_MA_2 PF13485.6 EST43417.1 - 0.15 11.7 1.4 0.24 11.1 1.4 1.2 1 0 0 1 1 1 0 Peptidase MA superfamily FAD_syn PF06574.12 EST43418.1 - 0.42 10.5 2.6 1.3 8.9 2.0 1.9 1 1 1 2 2 2 0 FAD synthetase MLD PF11647.8 EST43418.1 - 2.5 8.4 5.2 16 5.8 0.0 3.0 3 0 0 3 3 3 0 Membrane Localization Domain VSP PF03302.13 EST43421.1 - 0.00061 18.8 220.7 0.003 16.5 34.3 7.2 1 1 6 7 7 7 6 Giardia variant-specific surface protein DUF4337 PF14235.6 EST43423.1 - 0.0059 16.7 1.6 0.01 16.0 1.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4337) TFR_dimer PF04253.15 EST43423.1 - 0.23 11.6 1.4 0.6 10.2 1.4 1.7 1 0 0 1 1 1 0 Transferrin receptor-like dimerisation domain Filament PF00038.21 EST43424.1 - 1.2e-08 34.9 89.4 0.00071 19.3 19.1 5.1 3 2 2 5 5 5 4 Intermediate filament protein DUF5044 PF16447.5 EST43424.1 - 0.0014 18.5 5.6 0.23 11.3 0.5 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF5044) HALZ PF02183.18 EST43424.1 - 0.0026 17.9 8.7 0.019 15.2 1.2 7.1 7 0 0 7 7 7 2 Homeobox associated leucine zipper HOOK PF05622.12 EST43424.1 - 0.0029 15.8 87.4 0.0013 17.0 63.2 2.3 1 1 1 2 2 2 1 HOOK protein BST2 PF16716.5 EST43424.1 - 0.0034 17.9 98.5 2 9.0 4.1 7.2 5 2 2 7 7 7 5 Bone marrow stromal antigen 2 Fib_alpha PF08702.10 EST43424.1 - 0.0041 17.3 64.1 0.015 15.5 11.9 5.4 2 1 3 5 5 5 3 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 EST43424.1 - 0.027 14.5 50.7 0.38 10.8 2.9 6.3 2 1 4 7 7 7 0 Protein of unknown function (DUF1664) YabA PF06156.13 EST43424.1 - 0.03 15.0 65.8 0.068 13.8 3.9 6.7 1 1 3 6 6 6 0 Initiation control protein YabA RTBV_P46 PF06216.11 EST43424.1 - 0.066 12.1 6.9 1.6 7.6 0.7 2.5 2 0 0 2 2 2 0 Rice tungro bacilliform virus P46 protein Golgin_A5 PF09787.9 EST43424.1 - 0.077 12.5 98.4 0.49 9.8 20.5 4.9 1 1 0 5 5 5 0 Golgin subfamily A member 5 TMF_DNA_bd PF12329.8 EST43424.1 - 0.089 12.8 83.1 0.73 9.9 0.3 8.4 7 2 2 9 9 9 0 TATA element modulatory factor 1 DNA binding MttA_Hcf106 PF02416.16 EST43424.1 - 0.096 12.0 1.8 19 4.7 0.1 3.6 2 0 0 2 2 2 0 mttA/Hcf106 family DUF4956 PF16316.5 EST43424.1 - 0.12 12.1 2.8 6.1 6.5 0.2 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4956) Atg14 PF10186.9 EST43424.1 - 0.13 11.3 67.2 0.23 10.5 21.4 3.8 1 1 3 4 4 4 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 EST43424.1 - 0.16 11.2 61.9 0.065 12.5 8.8 5.3 3 2 1 5 5 5 0 TMPIT-like protein YxiJ PF14176.6 EST43424.1 - 0.27 11.7 2.7 68 4.0 0.0 4.1 4 1 1 5 5 4 0 YxiJ-like protein Syntaxin PF00804.25 EST43424.1 - 0.44 10.2 52.8 0.038 13.6 10.2 4.9 1 1 0 3 3 3 0 Syntaxin DUF3584 PF12128.8 EST43424.1 - 0.48 7.9 89.8 0.63 7.5 47.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) ATG16 PF08614.11 EST43424.1 - 0.86 9.8 110.8 17 5.5 27.5 5.3 1 1 4 5 5 5 0 Autophagy protein 16 (ATG16) PSD2 PF07624.11 EST43424.1 - 0.98 9.2 9.1 56 3.6 0.3 5.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1585) Cauli_DNA-bind PF03310.13 EST43424.1 - 1.1 9.4 9.4 10 6.2 1.2 3.4 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein DUF4407 PF14362.6 EST43424.1 - 1.6 8.0 87.0 1.1 8.6 23.7 4.5 1 1 4 5 5 5 0 Domain of unknown function (DUF4407) DUF3800 PF12686.7 EST43424.1 - 2 9.0 4.7 3.6e+02 1.8 4.9 3.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) TPR_MLP1_2 PF07926.12 EST43424.1 - 2.8 8.0 106.7 0.14 12.2 13.2 7.0 3 2 4 7 7 7 0 TPR/MLP1/MLP2-like protein DUF812 PF05667.11 EST43424.1 - 3 6.6 84.9 3.5 6.4 41.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF812) HSR PF03172.13 EST43424.1 - 3.6 7.8 6.6 1.1e+02 3.0 0.1 3.8 3 0 0 3 3 3 0 HSR domain TSC22 PF01166.18 EST43424.1 - 3.9 7.9 55.5 0.076 13.3 3.7 8.2 5 2 4 9 9 9 0 TSC-22/dip/bun family CENP-F_leu_zip PF10473.9 EST43424.1 - 7.2 6.6 97.2 0.51 10.4 22.7 5.2 2 2 2 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BAAT_C PF08840.11 EST43424.1 - 9.2 6.1 10.2 21 5.0 0.0 4.1 5 0 0 5 5 5 0 BAAT / Acyl-CoA thioester hydrolase C terminal SHE3 PF17078.5 EST43424.1 - 9.3 5.9 66.0 1.9 8.2 22.2 5.1 1 1 3 4 4 4 0 SWI5-dependent HO expression protein 3 Fib_alpha PF08702.10 EST43425.1 - 0.0021 18.3 16.8 0.0021 18.3 16.8 3.4 1 1 1 3 3 2 1 Fibrinogen alpha/beta chain family Spc7 PF08317.11 EST43425.1 - 0.0064 15.4 22.5 0.0064 15.4 22.5 2.9 1 1 2 3 3 3 2 Spc7 kinetochore protein HALZ PF02183.18 EST43425.1 - 0.027 14.7 2.5 0.027 14.7 2.5 5.3 7 1 0 7 7 6 0 Homeobox associated leucine zipper YabA PF06156.13 EST43425.1 - 0.033 14.8 3.7 0.033 14.8 3.7 4.1 1 1 2 3 3 2 0 Initiation control protein YabA TSC22 PF01166.18 EST43425.1 - 0.037 14.3 3.5 0.037 14.3 3.5 5.3 4 1 2 6 6 6 0 TSC-22/dip/bun family SlyX PF04102.12 EST43425.1 - 0.22 12.2 0.3 0.22 12.2 0.3 5.7 1 1 5 6 6 6 0 SlyX ZapB PF06005.12 EST43425.1 - 1.2 9.6 0.1 0.099 13.1 9.8 6.4 2 1 3 5 5 4 0 Cell division protein ZapB DUF1515 PF07439.11 EST43425.1 - 2.3 8.3 9.3 3.2 7.8 4.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) DUF1664 PF07889.12 EST43425.1 - 2.7 8.1 28.3 0.22 11.6 3.2 3.8 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) YtxH PF12732.7 EST43425.1 - 3.7 8.2 13.5 3.1e+03 -1.2 13.5 3.9 1 1 0 1 1 1 0 YtxH-like protein DUF3037 PF11236.8 EST43425.1 - 7.6 7.0 15.6 13 6.2 7.0 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3037) PreAtp-grasp PF18604.1 EST43426.1 - 0.78 9.4 3.3 0.89 9.2 0.1 2.7 3 0 0 3 3 3 0 Pre ATP-grasp domain CorA PF01544.18 EST43427.1 - 1.6 8.0 13.0 0.53 9.5 7.8 2.2 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein DivIC PF04977.15 EST43428.1 - 0.0066 16.2 5.7 0.0066 16.2 5.7 16.7 8 3 10 19 19 19 3 Septum formation initiator FlaC_arch PF05377.11 EST43428.1 - 0.02 15.3 5.0 0.02 15.3 5.0 12.5 10 3 1 11 11 11 0 Flagella accessory protein C (FlaC) Epsilon_antitox PF08998.11 EST43429.1 - 0.0086 16.3 1.0 0.033 14.4 0.1 2.3 2 0 0 2 2 2 1 Bacterial epsilon antitoxin Helicase_IV_N PF12462.8 EST43429.1 - 0.015 15.2 0.2 0.038 13.9 0.1 1.7 1 1 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal UNC80 PF15778.5 EST43429.1 - 0.018 14.7 1.2 0.029 14.0 1.2 1.3 1 0 0 1 1 1 0 Cation channel complex component UNC80 PALP PF00291.25 EST43431.1 - 2.6e-56 191.2 0.0 3e-56 191.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DCP2 PF05026.13 EST43432.1 - 9.4 6.6 18.9 1.4 9.3 0.4 4.7 4 2 1 5 5 5 0 Dcp2, box A domain Pkinase PF00069.25 EST43434.1 - 5.9e-51 173.4 0.1 8e-51 172.9 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST43434.1 - 5e-30 104.6 0.0 6.9e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EST43434.1 - 1.9e-07 30.7 0.0 2.8e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EST43434.1 - 1e-06 28.0 0.4 1.8e-06 27.2 0.4 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EST43434.1 - 0.0049 16.2 0.3 0.011 15.1 0.2 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4395 PF14340.6 EST43434.1 - 0.2 12.0 0.2 0.47 10.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4395) DUF1730 PF08331.10 EST43435.1 - 0.12 12.3 0.6 0.24 11.4 0.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1730) DUF3543 PF12063.8 EST43436.1 - 0.047 13.1 0.1 0.049 13.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3543) Kinesin PF00225.23 EST43437.1 - 1.1e-81 274.3 6.2 1.8e-81 273.6 6.2 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EST43437.1 - 3.3e-19 69.3 0.9 3.3e-19 69.3 0.9 2.2 2 0 0 2 2 2 1 Microtubule binding DUF3671 PF12420.8 EST43438.1 - 0.015 15.4 2.7 0.048 13.8 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF3139 PF11337.8 EST43438.1 - 8.9 7.0 8.2 10 6.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Peptidase_C1 PF00112.23 EST43439.1 - 2e-29 103.3 0.5 2.9e-29 102.7 0.5 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Myb_DNA-bind_6 PF13921.6 EST43441.1 - 1.1e-07 31.9 1.3 1.1e-07 31.9 1.3 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Rap1_C PF11626.8 EST43441.1 - 0.00014 21.9 1.2 0.18 11.9 0.1 2.2 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-binding PF00249.31 EST43441.1 - 0.017 15.3 8.9 0.47 10.7 1.0 3.4 2 2 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 EST43441.1 - 0.079 14.0 5.5 0.72 10.9 1.2 2.7 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF273 PF03314.14 EST43441.1 - 0.14 11.7 2.2 2.5 7.6 0.2 2.2 1 1 0 2 2 2 0 Protein of unknown function, DUF273 Myb_DNA-bind_5 PF13873.6 EST43441.1 - 0.19 11.8 2.9 5.3 7.2 0.1 2.9 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST43445.1 - 1.1e-07 31.9 1.3 1.1e-07 31.9 1.3 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Rap1_C PF11626.8 EST43445.1 - 0.00014 21.9 1.2 0.18 11.9 0.1 2.2 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-binding PF00249.31 EST43445.1 - 0.017 15.3 8.9 0.47 10.7 1.0 3.4 2 2 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 EST43445.1 - 0.079 14.0 5.5 0.72 10.9 1.2 2.7 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF273 PF03314.14 EST43445.1 - 0.14 11.7 2.2 2.5 7.6 0.2 2.2 1 1 0 2 2 2 0 Protein of unknown function, DUF273 Myb_DNA-bind_5 PF13873.6 EST43445.1 - 0.19 11.8 2.9 5.3 7.2 0.1 2.9 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain Ank_2 PF12796.7 EST43447.1 - 8.5e-10 39.1 0.8 2.7e-08 34.3 0.1 2.6 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EST43447.1 - 3.9e-06 27.0 6.0 0.014 15.7 0.6 4.2 2 1 2 4 4 4 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EST43447.1 - 2.3e-05 24.8 0.7 0.0026 18.3 0.1 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 EST43447.1 - 0.0013 19.1 2.5 0.024 15.1 0.3 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 EST43447.1 - 0.0016 18.8 5.7 0.073 13.7 0.3 4.0 4 0 0 4 4 4 1 Ankyrin repeat DUF5101 PF17031.5 EST43447.1 - 0.013 15.6 0.1 0.025 14.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5101) PikAIV_N PF18605.1 EST43447.1 - 0.029 13.9 9.5 0.14 11.7 2.5 2.4 1 1 1 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain NRBF2 PF08961.10 EST43447.1 - 0.044 13.4 0.9 0.044 13.4 0.9 2.1 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator ZapB PF06005.12 EST43447.1 - 0.084 13.3 3.1 0.16 12.4 3.1 1.4 1 0 0 1 1 1 0 Cell division protein ZapB HALZ PF02183.18 EST43447.1 - 0.093 13.0 1.1 0.33 11.2 1.1 2.0 1 0 0 1 1 1 0 Homeobox associated leucine zipper Shugoshin_N PF07558.11 EST43447.1 - 0.24 11.3 4.0 1.8 8.5 1.9 2.5 1 1 1 2 2 2 0 Shugoshin N-terminal coiled-coil region Kinesin PF00225.23 EST43448.1 - 9.6e-79 264.7 2.5 9.6e-79 264.7 2.5 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EST43448.1 - 6.2e-17 61.9 0.3 3.2e-16 59.6 0.0 2.5 2 0 0 2 2 2 1 Microtubule binding UPF0184 PF03670.13 EST43448.1 - 0.68 10.4 3.5 8.9 6.8 0.0 3.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) Peptidase_C1 PF00112.23 EST43450.1 - 0.00022 21.4 0.0 0.00039 20.6 0.0 1.3 1 0 0 1 1 1 1 Papain family cysteine protease DUF1282 PF06930.12 EST43450.1 - 0.0056 16.5 1.9 0.012 15.4 1.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) Adeno_E3_CR2 PF02439.15 EST43450.1 - 0.052 13.3 0.6 0.052 13.3 0.6 2.0 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Vpu PF00558.19 EST43450.1 - 0.099 12.4 0.6 0.17 11.6 0.6 1.3 1 0 0 1 1 1 0 Vpu protein CCDC-167 PF15188.6 EST43452.1 - 0.0075 16.6 0.1 0.017 15.5 0.1 1.6 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 PspA_IM30 PF04012.12 EST43452.1 - 0.044 13.4 5.1 0.056 13.0 4.2 1.7 1 1 0 1 1 1 0 PspA/IM30 family Snf7 PF03357.21 EST43452.1 - 0.44 10.1 8.2 12 5.5 8.2 2.2 1 1 0 1 1 1 0 Snf7 Filament PF00038.21 EST43453.1 - 1.5e-09 37.9 171.7 3.7e-06 26.7 34.2 8.0 1 1 6 7 7 7 6 Intermediate filament protein FAM184 PF15665.5 EST43453.1 - 2.7e-09 37.1 11.0 2.7e-09 37.1 11.0 8.3 1 1 6 8 8 8 2 Family with sequence similarity 184, A and B Spc7 PF08317.11 EST43453.1 - 0.0022 17.0 24.7 0.0022 17.0 24.7 8.7 2 2 7 9 9 9 6 Spc7 kinetochore protein Laminin_II PF06009.12 EST43453.1 - 0.0088 16.1 13.6 0.0088 16.1 13.6 10.6 2 2 8 12 12 12 2 Laminin Domain II MtrB PF05440.12 EST43453.1 - 1.8 9.0 5.3 9.8 6.7 0.2 4.1 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B RGS12_us1 PF16613.5 EST43453.1 - 3.2 8.1 8.2 0.64 10.3 0.2 2.7 2 0 0 2 2 2 0 Unstructured region of RGS12 Aldose_epim PF01263.20 EST43457.1 - 0.099 11.9 1.5 0.16 11.3 1.5 1.3 1 0 0 1 1 1 0 Aldose 1-epimerase ART PF01129.18 EST43458.1 - 0.028 13.7 0.0 5.8 6.1 0.0 2.1 2 0 0 2 2 2 0 NAD:arginine ADP-ribosyltransferase TMEM154 PF15102.6 EST43459.1 - 0.48 10.3 2.2 0.61 10.0 2.2 1.2 1 0 0 1 1 1 0 TMEM154 protein family Dpy-30 PF05186.13 EST43460.1 - 5.7e-09 35.5 0.0 7.5e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif DUF4985 PF16373.5 EST43460.1 - 0.012 16.0 0.0 0.013 15.9 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function B56 PF01603.20 EST43461.1 - 7.6e-102 341.4 30.1 8e-94 314.9 18.8 3.1 1 1 1 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) ABC_membrane_3 PF13748.6 EST43462.1 - 0.0021 17.3 0.6 0.0021 17.3 0.6 1.8 2 0 0 2 2 2 1 ABC transporter transmembrane region FlaC_arch PF05377.11 EST43462.1 - 0.078 13.4 0.6 0.078 13.4 0.6 6.5 8 0 0 8 8 8 0 Flagella accessory protein C (FlaC) DUF98 PF01947.16 EST43463.1 - 0.028 14.4 0.4 0.23 11.4 0.0 2.1 2 0 0 2 2 2 0 p-hydroxybenzoic acid synthase Peripla_BP_2 PF01497.18 EST43464.1 - 0.017 14.7 0.9 0.019 14.6 0.9 1.1 1 0 0 1 1 1 0 Periplasmic binding protein DUF1664 PF07889.12 EST43464.1 - 0.037 14.1 6.2 1.6 8.7 0.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) BRI3BP PF14965.6 EST43464.1 - 0.051 13.1 0.8 0.088 12.3 0.8 1.4 1 0 0 1 1 1 0 Negative regulator of p53/TP53 Allexi_40kDa PF05549.11 EST43464.1 - 0.064 12.8 4.3 0.078 12.5 2.6 1.8 1 1 1 2 2 2 0 Allexivirus 40kDa protein ABC_tran_CTD PF16326.5 EST43464.1 - 5.4 7.3 9.9 0.45 10.8 1.7 2.9 1 1 2 3 3 3 0 ABC transporter C-terminal domain Pribosyltran_N PF13793.6 EST43465.1 - 3.9e-38 130.0 0.0 6.1e-36 122.9 0.0 2.7 3 0 0 3 3 3 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EST43465.1 - 1.3e-15 57.9 0.1 2.1e-15 57.2 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EST43465.1 - 3.1e-10 39.8 0.1 8.3e-10 38.4 0.0 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain Ribo_biogen_C PF04034.13 EST43467.1 - 3.4e-38 130.2 0.2 9.9e-38 128.7 0.0 1.7 1 1 1 2 2 2 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 EST43467.1 - 2.5e-09 36.8 0.3 4.5e-09 36.0 0.3 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI NDK PF00334.19 EST43468.1 - 3.1e-56 189.1 0.0 3.5e-56 188.9 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase MFS_1 PF07690.16 EST43469.1 - 2.3e-07 30.1 50.5 2.3e-07 30.1 50.5 3.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_53 PF07745.13 EST43471.1 - 0.026 13.5 0.2 0.029 13.3 0.2 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 Rogdi_lz PF10259.9 EST43471.1 - 0.16 11.4 2.8 0.21 11.0 2.8 1.2 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein Vma12 PF11712.8 EST43471.1 - 0.84 9.7 4.0 1.6 8.8 3.6 1.8 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase KIAA1430 PF13879.6 EST43471.1 - 1.5 9.6 6.6 9.6 7.0 3.3 2.7 2 1 1 3 3 3 0 KIAA1430 homologue Dynein_heavy PF03028.15 EST43473.1 - 0.16 12.0 1.4 0.31 11.1 0.1 2.1 3 0 0 3 3 3 0 Dynein heavy chain region D6 P-loop domain PAPS_reduct PF01507.19 EST43474.1 - 4.2e-19 69.2 0.0 5.5e-10 39.6 0.0 2.3 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family EF-hand_1 PF00036.32 EST43475.1 - 8.9e-06 24.9 3.2 0.093 12.3 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EST43475.1 - 1.4e-05 24.7 0.7 0.21 11.6 0.0 3.0 2 1 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EST43475.1 - 1.9e-05 25.0 4.7 0.00033 21.0 0.8 1.9 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 EST43475.1 - 4.3e-05 23.3 0.6 0.045 13.6 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EST43475.1 - 0.00022 20.6 0.3 0.043 13.3 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_4 PF12763.7 EST43475.1 - 0.00092 19.1 2.5 0.9 9.5 0.0 2.8 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand zf-C3HC4_3 PF13920.6 EST43476.1 - 0.29 11.0 12.4 0.64 9.9 12.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Myb_DNA-binding PF00249.31 EST43477.1 - 0.00035 20.7 0.1 0.00085 19.5 0.0 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST43477.1 - 0.011 16.0 0.3 0.044 14.0 0.2 2.1 1 1 1 2 2 2 0 Myb-like DNA-binding domain PBC PF03792.13 EST43477.1 - 0.033 13.9 0.1 0.045 13.5 0.1 1.1 1 0 0 1 1 1 0 PBC domain Peptidase_C1 PF00112.23 EST43478.1 - 1e-99 333.0 18.3 7e-55 186.5 3.3 2.3 2 0 0 2 2 2 2 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EST43478.1 - 5.6e-05 22.1 12.8 0.64 8.7 0.1 4.3 4 0 0 4 4 4 4 Peptidase C1-like family Baculo_PEP_C PF04513.12 EST43479.1 - 0.042 13.9 2.0 0.047 13.7 1.0 1.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 EST43479.1 - 0.5 10.4 5.7 0.45 10.6 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 EST43480.1 - 0.0094 16.1 12.5 0.0094 16.1 12.5 9.0 2 1 6 8 8 8 2 Uncharacterised protein family (UPF0242) N-terminus Csm1_N PF18504.1 EST43480.1 - 0.041 14.2 0.4 0.041 14.2 0.4 16.2 6 3 10 18 18 18 0 Csm1 N-terminal domain bZIP_1 PF00170.21 EST43482.1 - 0.012 15.7 1.6 0.012 15.7 1.6 4.0 2 1 2 4 4 4 0 bZIP transcription factor RNase_H PF00075.24 EST43482.1 - 0.11 12.7 8.1 0.095 12.9 0.5 2.4 1 1 1 2 2 2 0 RNase H Tho2 PF11262.8 EST43482.1 - 0.99 8.5 19.5 0.19 10.9 8.6 2.2 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 TSC22 PF01166.18 EST43482.1 - 6.2 7.2 23.4 0.24 11.7 2.4 3.7 3 0 0 3 3 3 0 TSC-22/dip/bun family DUF724 PF05266.14 EST43482.1 - 7.9 6.3 24.4 0.99 9.2 5.5 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF724) EF-hand_7 PF13499.6 EST43483.1 - 3.4e-06 27.4 4.6 6.6e-05 23.3 0.8 1.8 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 EST43483.1 - 4.1e-06 25.9 3.3 0.06 12.9 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EST43483.1 - 4.2e-06 26.3 0.8 0.059 13.3 0.0 3.0 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EST43483.1 - 2.7e-05 23.9 1.6 0.045 13.6 0.1 2.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EST43483.1 - 0.00013 21.3 0.4 0.026 14.0 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_4 PF12763.7 EST43483.1 - 0.00081 19.3 2.5 0.9 9.5 0.0 2.8 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand LRR_8 PF13855.6 EST43486.1 - 6e-07 29.1 4.8 0.00044 19.9 0.7 2.3 1 1 2 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 EST43486.1 - 0.0077 16.6 0.4 1.4 9.8 0.1 3.6 3 0 0 3 3 3 1 Leucine Rich Repeat LRRNT_2 PF08263.12 EST43486.1 - 0.012 15.9 0.1 0.024 14.9 0.1 1.5 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain LRR_4 PF12799.7 EST43486.1 - 0.013 15.9 1.6 0.19 12.2 0.6 2.9 1 1 0 2 2 2 0 Leucine Rich repeats (2 copies) MIEAP PF16026.5 EST43487.1 - 0.017 15.3 0.3 0.026 14.7 0.1 1.4 2 0 0 2 2 2 0 Mitochondria-eating protein PK PF00224.21 EST43489.1 - 2.9e-75 253.3 0.9 3.4e-75 253.1 0.9 1.0 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain HpcH_HpaI PF03328.14 EST43489.1 - 0.0033 16.6 1.7 0.011 14.9 1.7 1.9 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family HALZ PF02183.18 EST43490.1 - 0.071 13.3 1.8 0.56 10.5 0.2 3.1 2 1 0 2 2 2 0 Homeobox associated leucine zipper YueH PF14166.6 EST43490.1 - 0.075 12.9 0.3 0.28 11.0 0.1 2.0 2 0 0 2 2 2 0 YueH-like protein Spc7 PF08317.11 EST43490.1 - 8 5.2 12.2 25 3.6 1.4 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF641 PF04859.12 EST43490.1 - 9.5 6.6 9.5 2.2 8.6 1.7 3.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DICT PF10069.9 EST43491.1 - 0.0092 15.7 0.1 0.01 15.6 0.1 1.2 1 0 0 1 1 1 1 Sensory domain in DIguanylate Cyclases and Two-component system Gal11_ABD1 PF18535.1 EST43492.1 - 1.2e-06 28.4 9.8 0.65 10.1 0.2 5.0 4 0 0 4 4 4 3 Gal11 activator-binding domain (ABD1) LPD14 PF18827.1 EST43492.1 - 1.4e-06 28.6 5.3 0.33 11.2 0.2 3.5 3 0 0 3 3 3 3 Large polyvalent protein-associated domain 14 YvrJ PF12841.7 EST43492.1 - 2.9e-06 26.7 7.8 7.5 6.2 0.0 8.0 6 0 0 6 6 6 3 YvrJ protein family ALIX_LYPXL_bnd PF13949.6 EST43492.1 - 7.3e-05 22.2 122.2 0.25 10.6 14.4 9.4 1 1 5 8 8 8 4 ALIX V-shaped domain binding to HIV HMMR_N PF15905.5 EST43492.1 - 0.00023 20.7 16.3 0.00023 20.7 16.3 7.3 2 2 5 7 7 6 3 Hyaluronan mediated motility receptor N-terminal FPP PF05911.11 EST43492.1 - 0.026 12.7 112.8 0.13 10.5 7.5 7.9 1 1 6 7 7 7 0 Filament-like plant protein, long coiled-coil FapA PF03961.13 EST43492.1 - 0.049 12.2 82.1 0.091 11.4 3.3 7.8 2 2 2 7 7 7 0 Flagellar Assembly Protein A Spc7 PF08317.11 EST43492.1 - 0.09 11.6 154.6 0.13 11.1 8.3 10.9 1 1 9 11 11 11 0 Spc7 kinetochore protein AIP3 PF03915.13 EST43492.1 - 0.34 10.0 71.7 0.2 10.7 2.1 6.8 2 2 1 5 5 5 0 Actin interacting protein 3 dbPDZ_assoc PF16610.5 EST43492.1 - 4.5 7.6 5.2 43 4.4 0.1 3.8 4 0 0 4 4 4 0 Unstructured region between two PDZ domains on Dlg5 B277 PF17623.2 EST43492.1 - 4.5 6.3 8.3 12 4.8 8.3 1.7 1 0 0 1 1 1 0 Domain of unknown function Adaptin_N PF01602.20 EST43493.1 - 7e-78 262.5 16.0 8.7e-78 262.1 16.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EST43493.1 - 8.4e-28 97.4 3.3 1.5e-25 90.1 0.5 2.8 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EST43493.1 - 2.4e-12 47.0 0.0 0.014 15.7 0.0 5.4 3 2 2 5 5 5 4 HEAT repeats HEAT PF02985.22 EST43493.1 - 8.1e-06 25.7 1.7 8.9 6.9 0.0 6.0 7 0 0 7 7 7 2 HEAT repeat FliG_C PF01706.16 EST43493.1 - 0.057 13.6 0.3 0.23 11.7 0.1 2.1 2 0 0 2 2 2 0 FliG C-terminal domain ABC_tran PF00005.27 EST43494.1 - 1.5e-36 125.9 0.0 1.5e-17 64.4 0.0 3.2 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EST43494.1 - 2.5e-33 115.9 53.5 6.2e-23 81.8 19.0 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EST43494.1 - 4.8e-10 39.2 0.0 0.0016 17.9 0.0 2.7 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EST43494.1 - 6.9e-06 26.1 0.4 0.26 11.0 0.1 4.0 4 1 0 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EST43494.1 - 0.00025 21.1 0.0 0.059 13.5 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.6 EST43494.1 - 0.0013 19.3 0.6 0.0013 19.3 0.6 3.4 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.17 EST43494.1 - 0.0021 18.2 0.3 1 9.4 0.0 2.8 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_29 PF13555.6 EST43494.1 - 0.0036 17.0 0.1 0.2 11.4 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EST43494.1 - 0.0042 17.0 0.0 0.11 12.4 0.0 2.7 3 0 0 3 3 3 1 RsgA GTPase MeaB PF03308.16 EST43494.1 - 0.028 13.4 0.0 1.1 8.2 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 EST43494.1 - 0.041 14.1 0.1 0.18 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EST43494.1 - 0.057 13.6 0.0 0.22 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EST43494.1 - 0.14 12.7 0.2 0.51 10.9 0.0 2.1 2 0 0 2 2 1 0 AAA domain Myb_DNA-binding PF00249.31 EST43495.1 - 7.1e-12 45.3 0.0 4.9e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST43495.1 - 4.5e-06 26.8 0.0 0.00034 20.8 0.0 2.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain Phage_lysozyme2 PF18013.1 EST43495.1 - 0.0048 16.9 0.1 0.0058 16.6 0.1 1.1 1 0 0 1 1 1 1 Phage tail lysozyme DUF722 PF05263.11 EST43495.1 - 0.088 13.0 0.0 2.2 8.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF722) MFS_1 PF07690.16 EST43496.1 - 1.7e-20 73.2 21.8 9.2e-11 41.3 7.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EST43496.1 - 0.00025 19.7 26.0 0.0014 17.3 26.1 2.2 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 EST43497.1 - 6.2e-12 45.1 34.5 6.2e-12 45.1 34.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily SPC12 PF06645.13 EST43498.1 - 2.1e-12 46.9 1.1 2.3e-12 46.8 1.1 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Bap31_Bap29_C PF18035.1 EST43499.1 - 0.0069 16.4 3.9 0.94 9.5 0.9 2.6 2 0 0 2 2 2 2 Bap31/Bap29 cytoplasmic coiled-coil domain PHM7_cyt PF14703.6 EST43499.1 - 0.023 14.9 4.0 0.033 14.4 3.9 1.4 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter gpW PF02831.15 EST43499.1 - 0.029 14.3 0.2 4.3 7.3 0.0 2.7 2 0 0 2 2 2 0 gpW SIKE PF05769.11 EST43499.1 - 0.072 13.0 11.6 0.12 12.2 11.6 1.4 1 1 0 1 1 1 0 SIKE family Phage_GP20 PF06810.11 EST43499.1 - 0.09 12.6 13.2 0.4 10.5 5.2 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 CtIP_N PF10482.9 EST43499.1 - 0.11 12.5 11.3 0.033 14.2 7.6 2.0 1 1 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain GvpK PF05121.12 EST43499.1 - 0.12 12.5 3.4 1.2 9.2 0.3 2.4 2 0 0 2 2 2 0 Gas vesicle protein K Myc-LZ PF02344.15 EST43499.1 - 0.13 12.4 1.8 2.4 8.3 0.1 3.3 3 0 0 3 3 3 0 Myc leucine zipper domain DUF4407 PF14362.6 EST43499.1 - 0.14 11.5 11.5 0.18 11.2 11.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.11 EST43499.1 - 0.16 12.4 4.6 9.3 6.7 0.4 2.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) V_ATPase_I PF01496.19 EST43499.1 - 0.18 9.7 7.6 0.21 9.5 7.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.15 EST43499.1 - 0.21 11.4 13.0 0.45 10.3 0.3 2.6 3 0 0 3 3 3 0 Septum formation initiator DUF948 PF06103.11 EST43499.1 - 0.23 11.7 2.2 0.36 11.1 0.8 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) BST2 PF16716.5 EST43499.1 - 0.61 10.7 16.1 0.58 10.8 2.1 2.8 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 Cnn_1N PF07989.11 EST43499.1 - 0.63 10.2 10.7 0.73 10.0 3.8 2.7 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 GAS PF13851.6 EST43499.1 - 1.1 8.6 15.8 1.9 7.8 2.4 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding NPV_P10 PF05531.12 EST43499.1 - 1.2 9.7 9.1 1.3 9.5 2.3 2.5 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein Cep57_CLD_2 PF14197.6 EST43499.1 - 1.4 9.1 9.7 6.3 7.0 3.0 2.7 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 ZapB PF06005.12 EST43499.1 - 1.8 9.1 17.8 0.9 10.0 9.8 2.6 2 1 0 2 2 2 0 Cell division protein ZapB KIAA1430 PF13879.6 EST43499.1 - 1.9 9.3 9.2 4.7 8.0 9.1 1.8 1 1 0 1 1 1 0 KIAA1430 homologue CHASE3 PF05227.13 EST43499.1 - 2.3 8.2 14.2 30 4.5 10.6 2.9 2 1 0 2 2 2 0 CHASE3 domain Snapin_Pallidin PF14712.6 EST43499.1 - 2.4 8.6 9.3 1.2 9.7 3.6 2.3 1 1 1 2 2 2 0 Snapin/Pallidin APC_N_CC PF16689.5 EST43499.1 - 2.5 8.3 6.8 0.64 10.1 2.2 2.2 2 1 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain APG6_N PF17675.1 EST43499.1 - 2.6 8.6 14.6 5.8 7.5 13.4 2.2 1 1 0 1 1 1 0 Apg6 coiled-coil region Med9 PF07544.13 EST43499.1 - 3.6 7.8 8.7 11 6.2 1.4 2.5 1 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 JIP_LZII PF16471.5 EST43499.1 - 5.3 7.3 9.5 0.48 10.6 1.1 2.8 2 2 1 3 3 3 0 JNK-interacting protein leucine zipper II TolA_bind_tri PF16331.5 EST43499.1 - 5.6 7.1 14.3 0.42 10.7 1.3 3.2 3 1 0 3 3 3 0 TolA binding protein trimerisation Swi5 PF07061.11 EST43499.1 - 6.3 7.0 10.8 11 6.2 0.9 2.7 1 1 1 2 2 2 0 Swi5 bZIP_1 PF00170.21 EST43499.1 - 6.5 6.9 14.4 0.21 11.7 1.4 3.0 2 1 2 4 4 4 0 bZIP transcription factor bZIP_Maf PF03131.17 EST43499.1 - 6.8 7.3 15.5 3.4 8.3 1.5 3.1 1 1 2 3 3 3 0 bZIP Maf transcription factor Csm1_N PF18504.1 EST43499.1 - 9.8 6.6 13.5 13 6.2 1.0 3.4 2 1 1 3 3 3 0 Csm1 N-terminal domain PRKG1_interact PF15898.5 EST43499.1 - 9.9 7.1 12.9 4.1 8.3 7.8 2.2 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Myb_DNA-binding PF00249.31 EST43500.1 - 1.3e-12 47.7 3.7 2.3e-06 27.7 0.6 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST43500.1 - 1.2e-10 41.4 7.8 2.4e-09 37.3 4.6 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EST43500.1 - 0.0043 17.2 5.5 0.2 11.8 0.5 2.2 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 HTH_32 PF13565.6 EST43500.1 - 0.029 15.0 0.6 0.7 10.5 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain Tox-GHH PF15636.6 EST43500.1 - 0.79 9.7 4.1 0.56 10.2 0.8 2.2 1 1 1 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin PP2C PF00481.21 EST43501.1 - 9.3e-22 77.9 0.3 1.8e-21 76.9 0.3 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EST43501.1 - 0.00019 21.1 0.0 0.00047 19.9 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C Ank_2 PF12796.7 EST43502.1 - 3.7e-33 114.0 18.7 3.9e-10 40.2 0.7 4.5 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EST43502.1 - 2.3e-17 62.8 5.6 0.0004 20.6 0.1 6.3 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 EST43502.1 - 3e-16 59.0 0.8 0.017 15.5 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.6 EST43502.1 - 7.4e-16 58.3 5.6 0.018 15.6 0.0 6.0 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EST43502.1 - 2.5e-14 52.0 2.6 0.56 10.9 0.0 8.0 9 0 0 9 9 9 4 Ankyrin repeat SPC12 PF06645.13 EST43503.1 - 2.1e-12 46.9 1.1 2.3e-12 46.8 1.1 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) MFS_2 PF13347.6 EST43504.1 - 0.00026 19.7 1.8 0.00034 19.3 1.8 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 EST43505.1 - 5.6e-21 74.9 23.2 4.6e-11 42.2 8.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EST43505.1 - 6.4e-05 21.7 28.7 0.00027 19.6 28.7 2.0 1 1 0 1 1 1 1 MFS/sugar transport protein Myb_DNA-binding PF00249.31 EST43506.1 - 2.2e-10 40.5 0.0 0.00017 21.7 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST43506.1 - 2.6e-06 27.6 0.0 0.00015 22.0 0.0 2.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EST43507.1 - 1e-10 41.6 0.4 8.4e-05 22.7 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST43507.1 - 5.6e-05 23.3 0.0 0.032 14.5 0.0 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 EST43507.1 - 0.062 13.6 0.0 5.1 7.5 0.0 2.3 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like ABC_tran PF00005.27 EST43508.1 - 1.4e-24 87.2 0.1 1.4e-24 87.2 0.1 2.4 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.6 EST43508.1 - 7e-07 29.3 4.5 0.0031 17.4 0.0 3.1 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EST43508.1 - 0.00028 20.4 0.4 0.0097 15.4 0.4 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EST43508.1 - 0.0011 19.5 3.5 0.0014 19.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EST43508.1 - 0.065 13.1 2.0 0.085 12.8 0.0 2.2 3 0 0 3 3 3 0 RsgA GTPase AAA_29 PF13555.6 EST43508.1 - 0.098 12.4 0.1 0.26 11.0 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_12 PF13087.6 EST43509.1 - 1.6e-48 165.0 0.1 1.6e-48 165.0 0.1 1.6 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EST43509.1 - 4e-34 118.6 3.4 1.3e-33 117.0 3.4 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EST43509.1 - 5.4e-14 52.3 11.8 6.4e-13 48.9 7.2 3.2 2 2 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EST43509.1 - 1.6e-11 44.7 5.8 1.5e-09 38.3 1.9 3.2 2 2 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 EST43509.1 - 2.2e-06 27.6 0.4 0.22 11.2 0.1 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 EST43509.1 - 9.5e-06 25.7 1.5 2.2e-05 24.5 0.1 2.3 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 EST43509.1 - 4.4e-05 23.4 5.6 0.027 14.3 3.3 3.5 2 1 0 2 2 2 1 Helicase AAA_22 PF13401.6 EST43509.1 - 0.00051 20.3 4.8 0.024 14.9 2.4 4.0 2 1 0 2 2 2 1 AAA domain PhoH PF02562.16 EST43509.1 - 0.0067 15.9 3.3 0.0088 15.5 0.1 2.6 3 0 0 3 3 3 1 PhoH-like protein AAA_24 PF13479.6 EST43509.1 - 0.0074 16.0 0.1 1.8 8.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 EST43509.1 - 0.0075 16.1 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain IstB_IS21 PF01695.17 EST43509.1 - 0.013 15.2 1.1 0.11 12.2 0.0 2.6 2 1 1 3 3 3 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 EST43509.1 - 0.015 14.7 0.2 0.047 13.1 0.1 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DEAD PF00270.29 EST43509.1 - 0.017 14.9 3.1 0.37 10.6 3.1 2.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase DUF2075 PF09848.9 EST43509.1 - 0.018 14.3 6.4 0.2 10.9 3.3 3.0 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SRP54 PF00448.22 EST43509.1 - 0.019 14.6 3.9 2 8.0 0.0 3.9 4 0 0 4 4 3 0 SRP54-type protein, GTPase domain FapA PF03961.13 EST43509.1 - 0.02 13.6 2.7 0.056 12.0 0.6 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A T2SSE PF00437.20 EST43509.1 - 0.022 13.8 0.0 0.062 12.4 0.0 1.8 1 0 0 1 1 1 0 Type II/IV secretion system protein Rad17 PF03215.15 EST43509.1 - 0.025 14.5 0.1 0.13 12.2 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain UvrD_C PF13361.6 EST43509.1 - 0.034 13.5 1.8 7.9 5.7 0.0 3.0 2 1 1 3 3 3 0 UvrD-like helicase C-terminal domain ATPase_2 PF01637.18 EST43509.1 - 0.063 13.2 0.0 0.2 11.5 0.0 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea cobW PF02492.19 EST43509.1 - 0.066 12.8 0.3 0.37 10.4 0.0 2.4 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Vta1_C PF18097.1 EST43509.1 - 0.074 12.8 1.8 2.2 8.0 0.0 3.4 3 0 0 3 3 3 0 Vta1 C-terminal domain ATPase PF06745.13 EST43509.1 - 0.084 12.2 0.6 0.27 10.6 0.6 1.8 1 1 0 1 1 1 0 KaiC DUF1690 PF07956.11 EST43509.1 - 0.089 13.2 3.5 0.23 11.9 3.5 1.6 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) AAA_16 PF13191.6 EST43509.1 - 0.11 12.9 1.4 0.37 11.2 1.4 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 EST43509.1 - 0.12 11.9 0.8 18 4.8 0.1 2.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EST43509.1 - 0.16 12.5 0.5 0.61 10.6 0.5 2.1 1 1 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 EST43509.1 - 0.2 12.1 2.8 8 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EST43509.1 - 0.42 11.0 4.5 1.3 9.5 2.4 3.0 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Cnn_1N PF07989.11 EST43509.1 - 0.79 9.9 7.6 0.69 10.1 3.1 2.6 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Csm1_N PF18504.1 EST43509.1 - 6.1 7.3 9.9 0.5 10.7 2.7 2.6 3 0 0 3 3 2 0 Csm1 N-terminal domain EF-hand_6 PF13405.6 EST43510.1 - 0.00017 21.2 0.0 0.088 12.8 0.0 3.1 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EST43510.1 - 0.0013 18.2 0.1 0.18 11.4 0.0 3.0 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 EST43510.1 - 0.0063 16.9 0.2 1.4 9.4 0.0 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EST43510.1 - 0.0066 16.3 0.1 5 7.0 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair HU-HIG PF18291.1 EST43510.1 - 0.046 13.8 0.2 0.12 12.4 0.1 1.8 2 1 1 3 3 3 0 HU domain fused to wHTH, Ig, or Glycine-rich motif DIM1 PF02966.16 EST43511.1 - 2.7e-14 53.1 0.1 3e-14 53.0 0.1 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 SOGA PF11365.8 EST43513.1 - 0.0014 19.7 5.2 0.0014 19.7 5.2 2.9 2 1 1 3 3 3 1 Protein SOGA DUF4763 PF15960.5 EST43513.1 - 0.0045 16.3 9.0 0.0045 16.3 9.0 2.6 2 1 1 3 3 3 1 Domain of unknown function (DUF4763) PTAC PF06130.12 EST43513.1 - 0.26 11.5 4.6 0.26 11.5 0.1 2.7 3 0 0 3 3 3 0 Phosphate propanoyltransferase Fucose_iso_N1 PF07881.12 EST43513.1 - 1.7 8.4 5.1 1.7 8.4 3.4 1.9 1 1 0 1 1 1 0 L-fucose isomerase, first N-terminal domain tRNA_edit PF04073.15 EST43514.1 - 5.9e-15 55.4 0.0 1.7e-14 54.0 0.0 1.7 2 0 0 2 2 2 1 Aminoacyl-tRNA editing domain 7tm_3 PF00003.22 EST43515.1 - 0.0093 15.7 1.0 0.01 15.6 1.0 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Cadherin_C_2 PF16492.5 EST43515.1 - 0.031 15.0 0.3 0.031 15.0 0.3 1.7 1 1 1 2 2 2 0 Cadherin cytoplasmic C-terminal DUF543 PF04418.12 EST43515.1 - 0.22 11.5 1.4 1.1 9.3 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF543) DUF4525 PF15027.6 EST43515.1 - 0.31 10.8 1.8 6 6.6 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4525) MFS_1 PF07690.16 EST43516.1 - 2.5e-27 95.7 57.9 2.5e-27 95.7 57.9 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EST43516.1 - 0.00037 19.5 16.3 0.00037 19.5 16.3 3.3 1 1 3 4 4 4 2 Sugar (and other) transporter Nnf1 PF03980.14 EST43517.1 - 0.03 14.7 7.9 0.03 14.7 7.9 3.5 2 2 1 3 3 3 0 Nnf1 Atg14 PF10186.9 EST43517.1 - 7.2 5.6 25.0 4.9e+02 -0.4 25.0 2.3 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Pkinase PF00069.25 EST43518.1 - 3.9e-39 134.6 0.0 1.9e-38 132.4 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST43518.1 - 3e-10 39.8 0.0 1.2e-07 31.3 0.0 2.5 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EST43518.1 - 3.7e-05 23.8 0.0 0.0064 16.4 0.0 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family DUF3857 PF12969.7 EST43518.1 - 0.0048 17.0 0.5 0.27 11.3 0.0 2.5 2 0 0 2 2 2 1 Domain of Unknown Function with PDB structure (DUF3857) UQ_con PF00179.26 EST43519.1 - 3.9e-22 78.4 0.0 4.4e-22 78.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Glycophorin_A PF01102.18 EST43521.1 - 0.0038 17.4 0.0 0.0067 16.7 0.0 1.3 1 0 0 1 1 1 1 Glycophorin A LAX PF15681.5 EST43521.1 - 0.21 10.4 0.8 0.47 9.2 0.1 1.9 3 0 0 3 3 3 0 Lymphocyte activation family X EphA2_TM PF14575.6 EST43521.1 - 0.92 10.4 0.1 0.92 10.4 0.1 2.2 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Trypan_PARP PF05887.11 EST43522.1 - 6.5e-06 26.2 6.9 1.4e-05 25.1 6.9 1.5 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Nrap_D4 PF17405.2 EST43523.1 - 0.036 13.4 0.4 0.075 12.4 0.4 1.5 1 0 0 1 1 1 0 Nrap protein nucleotidyltransferase domain 4 Maelstrom PF13017.6 EST43524.1 - 0.0036 17.0 0.0 0.0085 15.8 0.0 1.7 2 0 0 2 2 2 1 piRNA pathway germ-plasm component PAXX PF15384.6 EST43525.1 - 0.013 15.2 4.0 0.019 14.6 4.0 1.3 1 0 0 1 1 1 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 YabA PF06156.13 EST43525.1 - 0.2 12.3 3.7 0.26 11.9 1.0 2.3 2 1 1 3 3 3 0 Initiation control protein YabA APG6_N PF17675.1 EST43525.1 - 0.28 11.7 10.0 0.075 13.6 5.9 1.8 2 0 0 2 2 2 0 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 EST43525.1 - 0.3 11.3 5.2 1.2 9.4 1.4 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding ATG16 PF08614.11 EST43525.1 - 2.8 8.1 15.0 2.1 8.5 9.4 2.0 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) LRR_4 PF12799.7 EST43526.1 - 6.2e-06 26.5 14.6 0.0084 16.5 0.1 4.8 2 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EST43526.1 - 0.00029 20.6 12.8 0.23 11.2 0.7 4.8 2 1 2 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 EST43526.1 - 0.016 14.7 4.7 0.57 9.7 0.0 3.0 1 1 2 3 3 3 0 Leucine-rich repeat LRR_6 PF13516.6 EST43526.1 - 0.2 11.8 7.5 30 5.0 0.2 5.6 7 0 0 7 7 7 0 Leucine Rich repeat LRR_1 PF00560.33 EST43526.1 - 8.2 7.4 12.3 36 5.4 0.8 5.2 4 2 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 EST43529.1 - 0.0018 18.2 2.2 1.6 9.0 0.3 3.0 3 0 0 3 3 3 2 Leucine Rich repeat DUF89 PF01937.19 EST43529.1 - 0.008 15.2 0.3 0.0091 15.0 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF89 Atx10homo_assoc PF09759.9 EST43529.1 - 0.09 12.8 4.6 0.93 9.6 0.3 2.7 1 1 2 3 3 3 0 Spinocerebellar ataxia type 10 protein domain RNA_pol_A_CTD PF03118.15 EST43529.1 - 0.33 10.7 6.0 0.12 12.1 2.6 2.1 2 1 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain LRR_4 PF12799.7 EST43529.1 - 2.9 8.5 8.4 60 4.3 7.9 3.1 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) Myb_DNA-binding PF00249.31 EST43531.1 - 1.9e-19 69.6 0.2 2.8e-10 40.2 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST43531.1 - 1.8e-16 60.1 0.9 5.2e-14 52.2 0.4 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EST43531.1 - 0.00066 19.7 0.1 0.82 9.7 0.0 2.3 2 0 0 2 2 2 2 SLIDE Myb_DNA-bind_4 PF13837.6 EST43531.1 - 0.0023 18.3 2.1 0.06 13.7 0.2 2.8 2 2 0 2 2 2 1 Myb/SANT-like DNA-binding domain SLC12 PF03522.15 EST43533.1 - 0.25 10.3 10.6 0.36 9.8 10.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Exonuc_VII_L PF02601.15 EST43533.1 - 2.6 7.5 10.6 4.2 6.8 10.6 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Prok-RING_4 PF14447.6 EST43534.1 - 0.0071 16.2 9.7 0.013 15.4 9.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Baculo_p47 PF05112.12 EST43534.1 - 0.064 12.8 0.0 0.077 12.6 0.0 1.1 1 0 0 1 1 1 0 Baculovirus P47 protein zf-RING_2 PF13639.6 EST43534.1 - 0.071 13.5 12.2 0.12 12.7 12.2 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 EST43534.1 - 0.48 10.3 9.5 1.2 9.0 9.5 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EST43534.1 - 0.52 10.2 12.3 0.95 9.4 12.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EST43534.1 - 0.62 10.1 10.4 1.6 8.8 10.4 1.7 1 1 0 1 1 1 0 zinc-RING finger domain DUF4200 PF13863.6 EST43535.1 - 5.8e-06 26.7 4.4 5.8e-06 26.7 4.4 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4200) Spc7 PF08317.11 EST43535.1 - 0.0022 16.9 25.3 0.0031 16.4 13.5 2.3 2 0 0 2 2 2 2 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 EST43535.1 - 0.0069 16.4 5.1 0.0069 16.4 5.1 2.7 3 0 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3552 PF12072.8 EST43535.1 - 0.0083 15.6 3.9 0.0083 15.6 3.9 3.0 2 1 0 2 2 1 1 Domain of unknown function (DUF3552) CEP63 PF17045.5 EST43535.1 - 0.016 15.1 26.3 0.28 11.1 14.4 2.5 2 1 0 2 2 2 0 Centrosomal protein of 63 kDa TACC_C PF05010.14 EST43535.1 - 0.025 14.4 22.0 0.074 12.8 12.3 2.6 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal ATG16 PF08614.11 EST43535.1 - 0.096 12.9 33.5 0.089 13.0 18.7 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Corona_S2 PF01601.16 EST43535.1 - 0.18 10.3 4.0 0.34 9.3 4.0 1.5 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein HAUS-augmin3 PF14932.6 EST43535.1 - 0.24 11.0 20.6 0.66 9.5 10.9 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 ERM PF00769.19 EST43535.1 - 0.43 10.4 26.3 0.39 10.5 12.6 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Packaging_FI PF14000.6 EST43535.1 - 0.61 10.5 9.9 5.3 7.5 1.8 3.1 2 1 1 3 3 3 0 DNA packaging protein FI DUF2730 PF10805.8 EST43535.1 - 0.67 10.1 11.0 6.4 6.9 0.2 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) Jnk-SapK_ap_N PF09744.9 EST43535.1 - 0.99 9.6 30.5 2.8 8.1 0.7 3.4 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 DUF948 PF06103.11 EST43535.1 - 0.99 9.7 11.9 0.28 11.5 3.5 3.5 3 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Syntaxin-6_N PF09177.11 EST43535.1 - 1 10.0 20.4 1.7 9.2 9.5 3.3 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DUF4407 PF14362.6 EST43535.1 - 1.7 8.0 26.9 0.3 10.4 11.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 EST43535.1 - 2 7.9 30.5 0.17 11.5 5.7 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit DUF2935 PF11155.8 EST43535.1 - 2.5 8.5 10.8 5.4 7.4 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF2935) NPV_P10 PF05531.12 EST43535.1 - 3.3 8.2 20.4 1.3 9.5 8.6 4.4 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Golgin_A5 PF09787.9 EST43535.1 - 4.1 6.8 38.5 0.58 9.6 8.5 2.8 2 1 1 3 3 3 0 Golgin subfamily A member 5 FUSC PF04632.12 EST43535.1 - 5.1 5.5 9.6 0.23 9.9 2.0 1.9 2 0 0 2 2 2 0 Fusaric acid resistance protein family Nup54 PF13874.6 EST43535.1 - 7 6.8 27.8 6 7.0 4.0 2.6 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 DUF1515 PF07439.11 EST43535.1 - 8.4 6.5 15.2 0.44 10.6 0.2 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) CD99L2 PF12301.8 EST43536.1 - 1.3 9.3 7.0 2 8.7 6.9 1.5 1 1 0 1 1 1 0 CD99 antigen like protein 2 SlyX PF04102.12 EST43537.1 - 3.8e-06 27.4 21.8 0.00068 20.2 1.4 5.0 2 2 2 4 4 4 2 SlyX DUF3584 PF12128.8 EST43537.1 - 0.00021 19.0 23.9 0.00032 18.4 23.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) TolA_bind_tri PF16331.5 EST43537.1 - 0.00041 20.4 24.7 0.053 13.6 1.3 5.3 2 2 2 4 4 4 2 TolA binding protein trimerisation DUF4618 PF15397.6 EST43537.1 - 0.0037 16.7 11.2 0.0037 16.7 11.2 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4618) FlaC_arch PF05377.11 EST43537.1 - 0.0064 16.9 14.1 0.32 11.4 0.6 4.8 4 1 0 4 4 4 2 Flagella accessory protein C (FlaC) Spc42p PF11544.8 EST43537.1 - 0.012 15.6 3.1 4.5 7.3 0.3 3.3 3 0 0 3 3 3 0 Spindle pole body component Spc42p HIP1_clath_bdg PF16515.5 EST43537.1 - 0.016 15.8 35.4 0.37 11.4 4.6 3.9 2 2 2 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Spc7 PF08317.11 EST43537.1 - 0.017 14.0 31.5 0.033 13.1 14.1 2.9 1 1 0 2 2 2 0 Spc7 kinetochore protein Csm1_N PF18504.1 EST43537.1 - 0.091 13.1 24.5 0.79 10.1 1.4 5.0 2 2 2 4 4 4 0 Csm1 N-terminal domain GAS PF13851.6 EST43537.1 - 0.11 11.8 24.4 0.018 14.4 13.5 2.6 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding KASH_CCD PF14662.6 EST43537.1 - 0.14 11.9 31.1 0.23 11.2 22.9 2.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Lebercilin PF15619.6 EST43537.1 - 0.26 10.9 26.8 0.045 13.4 6.8 3.3 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DivIC PF04977.15 EST43537.1 - 0.37 10.6 24.5 0.17 11.7 1.2 5.1 3 2 2 5 5 5 0 Septum formation initiator TPR_MLP1_2 PF07926.12 EST43537.1 - 0.49 10.5 30.2 0.79 9.8 1.2 3.6 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein ADIP PF11559.8 EST43537.1 - 0.71 9.9 30.7 0.65 10.1 6.8 4.2 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding Cep57_CLD_2 PF14197.6 EST43537.1 - 0.77 9.9 25.0 0.54 10.4 0.8 5.0 2 2 2 4 4 4 0 Centrosome localisation domain of PPC89 Sec8_exocyst PF04048.14 EST43537.1 - 2.1 8.2 14.9 0.16 11.8 3.1 3.5 2 2 1 3 3 3 0 Sec8 exocyst complex component specific domain ATG16 PF08614.11 EST43537.1 - 3.8 7.7 31.3 0.96 9.6 16.7 3.1 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 EST43537.1 - 6.6 6.7 32.2 18 5.3 16.4 4.2 1 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Exo_endo_phos PF03372.23 EST43538.1 - 0.00073 19.1 0.0 0.0033 17.0 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DCB PF16213.5 EST43539.1 - 0.0079 15.9 2.5 0.027 14.1 2.5 1.9 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Nif11 PF07862.11 EST43539.1 - 0.047 14.0 0.1 9.3 6.7 0.0 3.0 3 0 0 3 3 3 0 Nif11 domain MatE PF01554.18 EST43540.1 - 1.5e-15 57.3 48.8 2.4e-09 37.0 21.9 2.8 2 1 0 2 2 2 2 MatE SpoU_sub_bind PF08032.12 EST43541.1 - 1.7 8.9 4.0 3.5 8.0 1.2 2.9 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding BcrAD_BadFG PF01869.20 EST43542.1 - 0.0079 15.7 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family HSP70 PF00012.20 EST43542.1 - 0.01 14.1 0.0 0.018 13.3 0.0 1.3 1 0 0 1 1 1 0 Hsp70 protein Novirhabdo_Nv PF05554.11 EST43542.1 - 0.072 12.8 0.1 0.36 10.6 0.0 2.2 2 0 0 2 2 2 0 Viral hemorrhagic septicemia virus non-virion protein IBR PF01485.21 EST43542.1 - 0.7 10.2 29.4 3.1 8.1 16.4 3.0 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain VSP PF03302.13 EST43543.1 - 7.1e-05 21.8 72.5 7.1e-05 21.8 72.5 5.7 1 1 3 4 4 4 3 Giardia variant-specific surface protein EphA2_TM PF14575.6 EST43543.1 - 0.13 13.1 0.4 0.48 11.3 0.4 2.0 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Steroid_dh PF02544.16 EST43544.1 - 3.9e-18 65.9 5.5 3.9e-18 65.9 5.5 2.4 1 1 1 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase Adeno_E4_34 PF04528.13 EST43544.1 - 0.036 13.9 0.7 0.054 13.3 0.7 1.3 1 0 0 1 1 1 0 Adenovirus early E4 34 kDa protein conserved region Lactamase_B_2 PF12706.7 EST43545.1 - 3.3e-05 23.5 0.0 5.2e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EST43545.1 - 0.002 18.2 0.0 0.0031 17.6 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Flavodoxin_1 PF00258.25 EST43545.1 - 0.0033 17.6 0.0 0.0065 16.7 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 EST43545.1 - 0.016 15.5 0.0 0.034 14.4 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain PGAP1 PF07819.13 EST43545.1 - 0.017 14.9 0.1 0.037 13.7 0.1 1.5 1 0 0 1 1 1 0 PGAP1-like protein eIF3g PF12353.8 EST43547.1 - 3.8e-06 27.3 1.9 3.8e-06 27.3 1.9 2.1 2 1 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G KSHV_K8 PF07188.11 EST43547.1 - 0.072 12.5 0.0 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 Kaposi's sarcoma-associated herpesvirus (KSHV) K8 protein DUF3919 PF13057.6 EST43548.1 - 0.15 11.6 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) Oxidored_FMN PF00724.20 EST43549.1 - 3.1e-30 105.6 4.1 1.6e-16 60.5 0.7 3.0 2 1 1 3 3 3 3 NADH:flavin oxidoreductase / NADH oxidase family Catalase_C PF18011.1 EST43549.1 - 0.014 15.0 0.1 0.042 13.5 0.1 1.8 2 0 0 2 2 2 0 C-terminal domain found in long catalases His_biosynth PF00977.21 EST43549.1 - 0.048 13.1 0.0 0.15 11.5 0.0 1.8 2 0 0 2 2 2 0 Histidine biosynthesis protein AP_endonuc_2 PF01261.24 EST43549.1 - 0.074 12.5 0.0 0.22 11.0 0.0 2.0 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel Phage_pRha PF09669.10 EST43549.1 - 0.097 13.2 0.2 0.26 11.9 0.2 1.7 1 0 0 1 1 1 0 Phage regulatory protein Rha (Phage_pRha) FMN_dh PF01070.18 EST43549.1 - 0.1 11.6 0.0 0.27 10.2 0.0 1.6 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Fer4 PF00037.27 EST43549.1 - 0.34 10.8 2.2 0.72 9.8 2.2 1.5 1 0 0 1 1 1 0 4Fe-4S binding domain HEAT PF02985.22 EST43550.1 - 0.0064 16.7 0.0 2.6 8.5 0.0 3.8 3 0 0 3 3 3 1 HEAT repeat DUF2721 PF11026.8 EST43551.1 - 0.008 16.1 3.2 0.013 15.4 2.9 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2721) DUF2207 PF09972.9 EST43551.1 - 0.064 12.0 1.4 0.1 11.3 1.4 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Cbl_N PF02262.16 EST43551.1 - 0.088 12.8 1.8 0.18 11.8 1.8 1.5 1 0 0 1 1 1 0 CBL proto-oncogene N-terminal domain 1 DUF2972 PF11186.8 EST43551.1 - 0.32 10.9 8.1 0.32 10.9 7.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2972) AOX PF01786.17 EST43551.1 - 2.4 7.7 5.8 0.12 12.0 0.2 1.6 2 0 0 2 2 2 0 Alternative oxidase PP2C PF00481.21 EST43552.1 - 2.7e-54 184.5 0.2 8.6e-54 182.9 0.0 1.7 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.12 EST43552.1 - 0.00041 20.3 0.1 0.0018 18.3 0.1 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Ank_2 PF12796.7 EST43553.1 - 0.0053 17.3 0.0 0.0077 16.8 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EST43553.1 - 0.013 15.9 0.0 0.05 14.1 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeat Csd3_N PF18059.1 EST43553.1 - 0.035 14.6 0.7 0.061 13.9 0.1 1.6 2 0 0 2 2 2 0 Csd3 N-terminal Ank_3 PF13606.6 EST43553.1 - 0.045 14.3 0.0 0.16 12.6 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeat HEAT PF02985.22 EST43554.1 - 4.1e-05 23.5 0.0 0.37 11.2 0.0 4.2 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 EST43554.1 - 0.00085 19.7 0.0 1.8 9.0 0.0 3.4 3 0 0 3 3 3 1 HEAT repeats HEAT_EZ PF13513.6 EST43554.1 - 0.0065 17.0 0.0 24 5.6 0.0 4.0 3 0 0 3 3 3 1 HEAT-like repeat NOB1_Zn_bind PF08772.11 EST43554.1 - 0.026 14.7 0.0 0.11 12.7 0.0 2.1 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like TUDOR PF00567.24 EST43554.1 - 0.051 13.6 2.8 14 5.8 0.1 3.9 4 0 0 4 4 4 0 Tudor domain TAN PF11640.8 EST43554.1 - 0.074 13.2 0.2 2.1 8.4 0.1 2.6 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair His_Phos_2 PF00328.22 EST43555.1 - 6.4e-14 52.1 0.1 1e-11 44.8 0.1 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) CTP-dep_RFKase PF01982.16 EST43556.1 - 0.036 14.2 1.3 0.058 13.5 0.3 1.7 1 1 1 2 2 2 0 Domain of unknown function DUF120 Brix PF04427.18 EST43557.1 - 2e-23 83.5 0.1 2.7e-23 83.1 0.1 1.2 1 0 0 1 1 1 1 Brix domain UPF0113_N PF17833.1 EST43560.1 - 1.8e-22 79.7 0.0 3.1e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 EST43560.1 - 2.1e-16 59.9 0.1 3.4e-16 59.3 0.1 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain EF-hand_5 PF13202.6 EST43561.1 - 5e-11 41.6 7.8 0.0013 18.1 0.0 3.7 3 0 0 3 3 3 3 EF hand EF-hand_1 PF00036.32 EST43561.1 - 5.2e-09 35.0 9.4 0.0015 18.0 0.2 3.9 3 1 1 4 4 4 3 EF hand EF-hand_7 PF13499.6 EST43561.1 - 5.7e-09 36.3 4.9 2.3e-06 27.9 2.5 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EST43561.1 - 7.6e-09 34.8 9.2 0.0015 18.3 0.2 4.0 3 2 1 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 EST43561.1 - 9.4e-07 28.6 6.3 0.01 15.7 0.1 3.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.7 EST43561.1 - 0.0017 18.3 2.9 0.0089 16.0 1.7 2.2 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 EST43561.1 - 0.0056 16.5 0.8 0.045 13.6 0.0 2.5 2 1 0 2 2 2 1 EF hand Dockerin_1 PF00404.18 EST43561.1 - 0.11 12.7 0.1 5.2 7.3 0.0 2.5 2 1 0 2 2 2 0 Dockerin type I domain RNase_HII PF01351.18 EST43562.1 - 0.18 11.6 0.2 0.44 10.3 0.2 1.6 1 0 0 1 1 1 0 Ribonuclease HII CALCOCO1 PF07888.11 EST43563.1 - 0.054 12.4 0.2 0.069 12.0 0.2 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like KASH_CCD PF14662.6 EST43563.1 - 0.13 12.0 1.1 0.21 11.4 1.1 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH HMG_box PF00505.19 EST43564.1 - 3.1e-06 27.5 5.9 1.6e-05 25.2 1.1 2.9 2 2 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EST43564.1 - 0.00026 21.5 2.5 0.00033 21.2 0.2 2.3 2 1 1 3 3 3 1 HMG-box domain DUF4081 PF13312.6 EST43564.1 - 0.00045 20.4 0.1 0.00063 19.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4081) PPP5 PF08321.12 EST43564.1 - 0.031 14.6 1.0 0.058 13.7 0.7 1.7 1 1 0 1 1 1 0 PPP5 TPR repeat region AATF-Che1 PF13339.6 EST43565.1 - 0.44 11.2 7.2 0.1 13.3 2.1 2.0 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor DUF4276 PF14103.6 EST43567.1 - 0.05 13.8 1.3 0.097 12.9 0.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4276) Ion_trans_2 PF07885.16 EST43568.1 - 6.5e-07 29.2 2.6 6.5e-07 29.2 2.6 1.9 1 1 1 2 2 2 1 Ion channel zf-RING_5 PF14634.6 EST43568.1 - 2.2e-05 24.3 10.2 2.2e-05 24.3 10.2 2.9 2 1 1 3 3 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EST43568.1 - 0.00032 20.5 10.0 0.00032 20.5 10.0 2.6 3 1 0 3 3 2 1 Prokaryotic RING finger family 4 DUF1345 PF07077.11 EST43568.1 - 0.0013 18.4 0.5 0.0023 17.7 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1345) zf-C3HC4_3 PF13920.6 EST43568.1 - 0.0015 18.4 11.3 0.0015 18.4 11.3 4.0 2 2 2 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EST43568.1 - 0.0076 16.1 13.1 0.0076 16.1 13.1 3.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EST43568.1 - 0.011 15.7 8.4 0.011 15.7 8.4 3.1 4 0 0 4 4 4 0 RING-type zinc-finger zf-C3HC4 PF00097.25 EST43568.1 - 0.021 14.7 12.9 0.021 14.7 12.9 3.3 2 1 1 3 3 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EST43568.1 - 0.027 14.6 10.1 0.027 14.6 10.1 2.9 3 1 0 3 3 2 0 zinc finger of C3HC4-type, RING zf-UDP PF14569.6 EST43568.1 - 0.63 10.2 15.9 0.21 11.7 5.9 2.6 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-RING_6 PF14835.6 EST43568.1 - 0.91 9.4 13.0 0.033 14.0 6.2 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein RabGAP-TBC PF00566.18 EST43570.1 - 0.00011 21.9 3.6 0.001 18.8 3.6 2.0 1 1 0 1 1 1 1 Rab-GTPase-TBC domain RICTOR_V PF14668.6 EST43571.1 - 0.016 15.5 1.5 0.056 13.7 0.4 2.5 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 ATP-grasp_6 PF18419.1 EST43571.1 - 0.026 14.2 0.4 0.11 12.1 0.1 2.2 2 0 0 2 2 2 0 ATP-grasp-like domain DUF1904 PF08921.11 EST43571.1 - 4.5 7.6 7.3 30 5.0 0.9 3.1 1 1 0 3 3 3 0 Domain of unknown function (DUF1904) DUF5584 PF17822.1 EST43572.1 - 0.018 14.5 0.4 0.044 13.2 0.4 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5584) Phage_int_SAM_1 PF02899.17 EST43573.1 - 0.11 12.8 2.3 1.9 8.8 0.2 2.8 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain zf-B_box PF00643.24 EST43574.1 - 6.9e-14 51.7 20.9 3.1e-09 36.8 7.4 2.8 3 0 0 3 3 2 2 B-box zinc finger DUF1640 PF07798.11 EST43574.1 - 0.035 14.2 0.9 0.035 14.2 0.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) TBCC_N PF16752.5 EST43574.1 - 0.051 14.0 1.0 0.051 14.0 1.0 2.5 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain Baculo_PEP_C PF04513.12 EST43574.1 - 0.052 13.6 0.7 0.052 13.6 0.7 2.6 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus NIT PF08376.10 EST43574.1 - 0.11 12.9 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 Nitrate and nitrite sensing DUF5082 PF16888.5 EST43574.1 - 0.61 10.4 11.9 0.13 12.6 1.1 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF5082) Exonuc_VII_L PF02601.15 EST43574.1 - 0.85 9.1 8.3 2.1 7.9 8.3 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit Streptin-Immun PF11083.8 EST43574.1 - 2.2 8.8 8.5 1.1 9.7 0.3 3.3 4 0 0 4 4 4 0 Lantibiotic streptin immunity protein FliJ PF02050.16 EST43574.1 - 4.8 7.4 9.4 0.89 9.8 0.4 3.1 2 1 1 3 3 3 0 Flagellar FliJ protein Phasin PF05597.11 EST43574.1 - 5.3 7.1 12.8 1.3 9.0 0.8 3.1 3 1 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) IBR PF01485.21 EST43574.1 - 9.1 6.6 26.8 0.19 12.0 2.7 3.5 4 0 0 4 4 3 0 IBR domain, a half RING-finger domain Glyco_hydro_35 PF01301.19 EST43575.1 - 5.2 6.6 10.5 2.2 7.8 5.5 1.9 1 1 1 2 2 2 0 Glycosyl hydrolases family 35 DUF3854 PF12965.7 EST43577.1 - 0.011 15.8 1.4 0.022 14.8 1.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) DUF1643 PF07799.12 EST43577.1 - 1 9.5 3.7 0.71 10.0 1.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1643) Ribosomal_L28e PF01778.17 EST43579.1 - 1.8e-26 93.1 0.6 6.1e-26 91.4 0.0 1.8 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 EST43579.1 - 7.7e-13 48.9 5.2 1.6e-12 47.9 5.2 1.5 1 0 0 1 1 1 1 Mak16 protein C-terminal region SecE PF00584.20 EST43580.1 - 0.00052 19.9 0.0 0.00063 19.6 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex HEPN_Swt1 PF18731.1 EST43581.1 - 0.13 12.6 0.4 0.53 10.6 0.1 2.1 2 0 0 2 2 2 0 Swt1-like HEPN IFT46_B_C PF12317.8 EST43582.1 - 7.1e-50 169.7 0.9 9.8e-50 169.2 0.9 1.2 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal Nucleoporin_FG PF13634.6 EST43583.1 - 0.27 12.1 45.6 5.1e+02 1.6 14.3 4.0 1 1 1 2 2 2 0 Nucleoporin FG repeat region ZapB PF06005.12 EST43583.1 - 1.8 9.1 6.3 0.17 12.3 1.4 1.9 2 0 0 2 2 2 0 Cell division protein ZapB NYD-SP28 PF14772.6 EST43584.1 - 0.0021 18.1 5.5 0.0028 17.7 4.1 2.0 2 0 0 2 2 2 1 Sperm tail PKcGMP_CC PF16808.5 EST43584.1 - 0.23 11.4 6.6 1.3 9.0 0.4 2.6 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ABC_tran_CTD PF16326.5 EST43584.1 - 1.5 9.1 7.1 0.97 9.7 4.3 2.1 2 0 0 2 2 2 0 ABC transporter C-terminal domain Fib_alpha PF08702.10 EST43584.1 - 4.6 7.4 19.4 0.57 10.4 12.1 2.9 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Osmo_CC PF08946.10 EST43584.1 - 8.8 6.7 8.1 16 5.9 1.0 2.7 1 1 1 2 2 2 0 Osmosensory transporter coiled coil EPTP PF03736.17 EST43585.1 - 0.73 9.9 4.6 0.67 10.0 0.1 3.1 3 0 0 3 3 3 0 EPTP domain Q_salvage PF10343.9 EST43587.1 - 0.02 14.5 0.3 0.028 14.0 0.3 1.2 1 0 0 1 1 1 0 Potential Queuosine, Q, salvage protein family TTL PF03133.15 EST43588.1 - 6.5e-39 133.8 7.1 6.5e-39 133.8 7.1 3.1 3 1 0 3 3 3 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EST43588.1 - 8.2e-06 25.3 1.9 0.017 14.4 0.0 3.2 2 1 1 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EST43588.1 - 0.0016 17.8 0.0 0.14 11.4 0.0 2.7 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp START PF01852.19 EST43590.1 - 0.001 18.5 0.0 0.0018 17.7 0.0 1.5 1 0 0 1 1 1 1 START domain zf-RING_5 PF14634.6 EST43591.1 - 1.2e-05 25.1 10.2 1.2e-05 25.1 10.2 3.3 3 1 1 4 4 4 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EST43591.1 - 0.00025 20.9 10.4 0.00025 20.9 10.4 3.0 3 1 1 4 4 4 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EST43591.1 - 0.0011 18.8 11.6 0.0011 18.8 11.6 4.3 2 2 2 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EST43591.1 - 0.0044 16.8 13.1 0.0044 16.8 13.1 3.5 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EST43591.1 - 0.0066 16.4 8.4 0.0066 16.4 8.4 3.5 4 0 0 4 4 4 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EST43591.1 - 0.016 15.1 13.3 0.016 15.1 13.3 3.6 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 EST43591.1 - 0.018 14.9 6.2 0.018 14.9 6.2 2.2 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 EST43591.1 - 0.019 15.3 12.3 0.019 15.3 12.3 3.7 2 1 1 3 3 3 0 Ring finger domain zf-UDP PF14569.6 EST43591.1 - 0.088 12.9 15.0 0.083 13.0 5.4 2.8 2 0 0 2 2 2 0 Zinc-binding RING-finger MutS_V PF00488.21 EST43592.1 - 3.7e-26 92.3 0.0 2.6e-25 89.5 0.0 2.2 1 1 0 1 1 1 1 MutS domain V AAA_29 PF13555.6 EST43592.1 - 0.0028 17.4 0.2 0.0073 16.0 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EST43592.1 - 0.0097 16.4 0.7 0.0097 16.4 0.7 3.8 3 1 0 3 3 3 1 AAA domain AAA_28 PF13521.6 EST43592.1 - 0.034 14.4 0.3 0.12 12.6 0.2 1.9 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 EST43592.1 - 0.04 13.3 3.1 4.3 6.7 1.2 3.7 4 1 0 4 4 4 0 RecF/RecN/SMC N terminal domain ABC_tran PF00005.27 EST43592.1 - 0.14 12.6 0.5 0.57 10.7 0.5 2.0 1 0 0 1 1 1 0 ABC transporter s48_45 PF07422.13 EST43592.1 - 0.17 12.5 5.1 2.9 8.5 0.3 3.9 3 0 0 3 3 3 0 Sexual stage antigen s48/45 domain AAA_14 PF13173.6 EST43592.1 - 0.93 9.5 5.1 1.3 9.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain START PF01852.19 EST43593.1 - 0.00096 18.6 0.0 0.0018 17.7 0.0 1.6 1 0 0 1 1 1 1 START domain JHD PF17811.1 EST43594.1 - 0.0026 18.3 0.1 0.02 15.4 0.1 2.4 2 0 0 2 2 2 1 Jumonji helical domain Ax_dynein_light PF10211.9 EST43595.1 - 0.0035 17.3 1.6 0.0035 17.3 1.6 4.6 3 1 2 5 5 5 1 Axonemal dynein light chain DUF1128 PF06569.11 EST43595.1 - 0.079 13.0 9.7 2.3 8.3 3.5 3.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1128) DUF2353 PF09789.9 EST43595.1 - 0.39 10.0 38.0 0.22 10.8 16.0 3.9 3 1 1 4 4 4 0 Uncharacterized coiled-coil protein (DUF2353) KORA PF16509.5 EST43595.1 - 0.52 10.6 0.1 0.52 10.6 0.1 3.0 3 1 0 3 3 3 0 TrfB plasmid transcriptional repressor MCPVI PF02993.14 EST43595.1 - 0.58 9.9 11.1 3.5 7.4 0.5 2.5 1 1 1 2 2 2 0 Minor capsid protein VI APG6_N PF17675.1 EST43595.1 - 0.77 10.3 35.0 0.13 12.8 12.7 4.7 3 1 1 4 4 4 0 Apg6 coiled-coil region Rbsn PF11464.8 EST43595.1 - 2.5 7.9 10.4 2.1 8.2 0.7 3.9 3 1 1 4 4 4 0 Rabenosyn Rab binding domain Ribosomal_L1 PF00687.21 EST43596.1 - 3.6e-05 23.6 0.3 0.0003 20.6 0.3 2.1 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family DHR10 PF18595.1 EST43597.1 - 0.0078 16.3 1.9 1.5 8.9 0.4 2.2 2 0 0 2 2 2 2 Designed helical repeat protein 10 domain DUF3867 PF12983.7 EST43597.1 - 0.012 15.7 3.3 0.029 14.4 3.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3867) DUF4296 PF14129.6 EST43597.1 - 0.029 15.0 0.3 0.071 13.7 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4296) EF-hand_1 PF00036.32 EST43597.1 - 0.029 13.9 0.1 9.1 6.1 0.0 3.1 3 0 0 3 3 3 0 EF hand FlaF PF07309.11 EST43597.1 - 0.046 13.7 0.7 0.088 12.8 0.1 1.7 2 0 0 2 2 2 0 Flagellar protein FlaF EF-hand_7 PF13499.6 EST43597.1 - 0.18 12.3 1.5 2.4 8.7 0.2 2.8 2 1 1 3 3 3 0 EF-hand domain pair Mcp5_PH PF12814.7 EST43599.1 - 2.1e-05 24.6 2.7 3.6e-05 23.9 0.3 2.6 2 1 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology Pkinase PF00069.25 EST43600.1 - 1.6e-18 67.0 0.0 2.3e-15 56.7 0.0 2.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST43600.1 - 7.7e-15 54.9 0.0 1.3e-11 44.3 0.0 2.5 1 1 1 2 2 2 2 Protein tyrosine kinase YolD PF08863.10 EST43600.1 - 0.012 15.7 1.7 0.012 15.7 1.7 2.7 2 0 0 2 2 2 0 YolD-like protein AAA PF00004.29 EST43601.1 - 6.4e-13 49.3 0.2 1.7e-12 47.9 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 EST43601.1 - 3.8e-07 30.4 0.4 2.2e-06 28.0 0.0 2.4 2 1 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 EST43601.1 - 6.1e-07 29.4 1.5 1.6e-06 28.0 0.2 2.2 2 1 1 3 3 3 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 EST43601.1 - 2.4e-05 24.6 1.2 6.5e-05 23.2 1.2 1.8 1 1 0 1 1 1 1 AAA C-terminal domain Mg_chelatase PF01078.21 EST43601.1 - 6e-05 22.5 0.0 0.0022 17.4 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 EST43601.1 - 7.5e-05 22.5 1.3 0.00056 19.7 0.1 2.7 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DNA_pol3_delta PF06144.13 EST43601.1 - 0.00014 21.7 0.3 0.00026 20.8 0.3 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.6 EST43601.1 - 0.00049 20.1 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EST43601.1 - 0.002 17.9 0.0 0.0042 16.8 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Vta1_C PF18097.1 EST43601.1 - 0.023 14.4 0.1 2.2 8.0 0.0 2.5 2 0 0 2 2 2 0 Vta1 C-terminal domain AAA_19 PF13245.6 EST43601.1 - 0.024 15.0 0.1 0.039 14.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EST43601.1 - 0.027 14.8 0.1 0.071 13.5 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.26 EST43601.1 - 0.036 13.8 0.0 7 6.3 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_5 PF07728.14 EST43601.1 - 0.038 14.0 0.3 0.46 10.5 0.0 2.5 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EST43601.1 - 0.064 13.1 0.0 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EST43601.1 - 0.14 12.4 1.2 3.9 7.7 0.2 2.9 2 1 1 3 3 3 0 AAA domain RNA_helicase PF00910.22 EST43601.1 - 0.16 12.3 0.0 0.7 10.3 0.0 2.1 3 0 0 3 3 3 0 RNA helicase V-ATPase_H_C PF11698.8 EST43601.1 - 0.8 9.8 3.0 1.2 9.3 0.1 2.4 3 0 0 3 3 2 0 V-ATPase subunit H DUF4490 PF14892.6 EST43603.1 - 2.7e-09 37.0 0.4 3.6e-09 36.6 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4490) DUF4907 PF16250.5 EST43603.1 - 0.037 13.9 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4907) DMAP1_like PF17024.5 EST43605.1 - 0.022 14.9 1.1 0.039 14.1 0.6 1.8 1 1 0 1 1 1 0 Putative DMAP1-like ketoacyl-synt PF00109.26 EST43605.1 - 0.069 12.7 0.1 0.078 12.5 0.1 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain HSCB_C PF07743.13 EST43605.1 - 0.071 13.6 5.6 1.1 9.8 0.2 2.8 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain Enkurin PF13864.6 EST43605.1 - 0.15 12.5 7.1 0.098 13.1 2.6 2.4 1 1 1 2 2 2 0 Calmodulin-binding DUF1664 PF07889.12 EST43605.1 - 0.98 9.5 6.0 0.91 9.6 2.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Nup54 PF13874.6 EST43605.1 - 1.2 9.2 12.9 1.8 8.7 1.1 2.3 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Jnk-SapK_ap_N PF09744.9 EST43605.1 - 4.4 7.5 9.4 4.6 7.5 5.1 2.0 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 NUFIP1 PF10453.9 EST43607.1 - 4.4e-07 29.6 1.2 9.7e-07 28.5 1.2 1.5 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Sin_N PF04801.13 EST43608.1 - 5.5e-21 75.3 2.1 1.7e-12 47.3 1.9 2.1 2 0 0 2 2 2 2 Sin-like protein conserved region HJURP_mid PF12346.8 EST43609.1 - 0.015 15.7 1.1 0.034 14.6 1.1 1.6 1 0 0 1 1 1 0 Holliday junction recognition protein-associated repeat CH_2 PF06294.11 EST43610.1 - 3.2e-13 49.6 1.2 3.2e-13 49.6 1.2 4.1 5 0 0 5 5 5 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 EST43610.1 - 0.00018 21.3 7.0 0.0012 18.6 0.0 4.1 4 0 0 4 4 4 1 CAMSAP CH domain CsgE PF10627.9 EST43610.1 - 0.046 14.0 0.5 0.21 11.8 0.1 2.4 2 0 0 2 2 2 0 Curli assembly protein CsgE EAP30 PF04157.16 EST43610.1 - 0.067 12.5 0.1 7.4 5.8 0.0 2.5 2 0 0 2 2 2 0 EAP30/Vps36 family Ig_4 PF16680.5 EST43610.1 - 0.79 10.0 5.3 11 6.4 0.1 3.4 3 0 0 3 3 3 0 T-cell surface glycoprotein CD3 delta chain Ank_2 PF12796.7 EST43611.1 - 6.3e-08 33.1 0.1 1.5e-07 31.9 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EST43611.1 - 0.029 14.8 0.0 0.098 13.1 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeat Ank_5 PF13857.6 EST43611.1 - 0.056 13.8 0.0 0.19 12.1 0.0 1.9 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 EST43611.1 - 0.062 13.9 0.0 3 8.5 0.0 2.8 3 0 0 3 3 3 0 Ankyrin repeats (many copies) DotU PF09850.9 EST43611.1 - 0.46 10.2 4.1 1.3 8.7 0.1 2.7 3 0 0 3 3 3 0 Type VI secretion system protein DotU KIP1 PF07765.12 EST43611.1 - 6.4 7.0 12.9 0.24 11.5 3.9 3.0 2 1 1 3 3 3 0 KIP1-like protein Radial_spoke PF04712.12 EST43613.1 - 1.8e-30 106.4 63.8 1.9e-15 56.8 10.9 6.1 3 2 1 4 4 4 3 Radial spokehead-like protein BING4CT PF08149.11 EST43613.1 - 0.28 11.0 1.6 0.4 10.5 0.0 2.0 2 0 0 2 2 2 0 BING4CT (NUC141) domain Rap1_C PF11626.8 EST43613.1 - 3.9 7.6 6.2 2.8 8.1 0.6 3.0 2 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Cation_ATPase_C PF00689.21 EST43614.1 - 2.9e-48 164.0 2.2 2.9e-48 164.0 2.2 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EST43614.1 - 3.8e-38 130.8 1.6 3.8e-38 130.8 1.6 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 EST43614.1 - 1e-13 50.8 0.1 2.9e-13 49.3 0.1 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 EST43614.1 - 1.6e-12 48.2 0.3 0.00016 22.0 0.0 3.5 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EST43614.1 - 2.5e-12 46.7 0.0 6.3e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EST43614.1 - 0.00066 19.5 0.2 0.00066 19.5 0.2 2.7 4 0 0 4 4 4 1 haloacid dehalogenase-like hydrolase RNA_pol_L_2 PF13656.6 EST43614.1 - 0.01 15.6 0.2 0.069 12.9 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain zf-CHY PF05495.12 EST43615.1 - 6e-07 29.9 23.6 6e-07 29.9 23.6 4.7 2 1 1 4 4 4 1 CHY zinc finger RHD_dimer PF16179.5 EST43615.1 - 0.015 15.3 3.2 0.045 13.8 0.6 2.6 2 0 0 2 2 2 0 Rel homology dimerisation domain OST_P2 PF18235.1 EST43617.1 - 0.02 14.8 0.2 0.02 14.8 0.2 3.0 3 0 0 3 3 3 0 Oligosaccharyltransferase Peripheral 2 domain DUF1999 PF09390.10 EST43617.1 - 0.15 11.7 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1999) Rep_fac_C PF08542.11 EST43617.1 - 0.89 10.0 4.3 2.3 8.7 0.1 3.6 3 0 0 3 3 3 0 Replication factor C C-terminal domain DUF3261 PF11659.8 EST43618.1 - 0.0089 15.9 3.0 0.02 14.8 3.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3261) zf-C2H2_9 PF16293.5 EST43618.1 - 0.089 12.6 2.3 14 5.7 0.1 3.0 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) DUF5077 PF16871.5 EST43618.1 - 0.19 11.6 8.2 0.39 10.6 7.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5077) CusF_Ec PF11604.8 EST43620.1 - 0.12 12.3 0.4 0.32 11.0 0.4 1.7 1 0 0 1 1 1 0 Copper binding periplasmic protein CusF DUF1690 PF07956.11 EST43621.1 - 0.028 14.8 7.7 0.04 14.3 5.5 2.3 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) LCAT PF02450.15 EST43622.1 - 2.6e-15 56.5 0.5 4.9e-14 52.3 0.1 2.2 1 1 0 2 2 2 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 EST43622.1 - 0.013 16.1 0.0 0.022 15.4 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 EST43622.1 - 0.16 11.9 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Hydrolase_4 PF12146.8 EST43622.1 - 0.16 11.2 0.0 0.3 10.3 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 FUSC PF04632.12 EST43623.1 - 0.064 11.8 2.0 0.084 11.4 2.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family FMN_dh PF01070.18 EST43623.1 - 0.87 8.6 7.6 0.14 11.2 3.2 1.7 2 0 0 2 2 2 0 FMN-dependent dehydrogenase APG6_N PF17675.1 EST43623.1 - 1.1 9.8 25.5 0.05 14.1 12.2 2.6 2 1 0 2 2 2 0 Apg6 coiled-coil region Actin PF00022.19 EST43624.1 - 2.3e-12 46.3 0.0 0.00011 21.0 0.0 3.0 1 1 2 3 3 3 3 Actin DUF1664 PF07889.12 EST43625.1 - 0.3 11.1 3.2 1.3 9.0 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) YbbR PF07949.12 EST43625.1 - 0.78 10.1 5.0 6.8 7.1 0.2 2.7 1 1 2 3 3 3 0 YbbR-like protein Ank_2 PF12796.7 EST43626.1 - 0.0026 18.3 0.2 0.0064 17.1 0.1 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EST43626.1 - 0.0053 17.1 0.0 0.32 11.4 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) KicB PF03882.14 EST43626.1 - 0.014 15.5 0.2 0.036 14.3 0.2 1.6 1 1 0 1 1 1 0 MukF winged-helix domain Ank_3 PF13606.6 EST43626.1 - 0.043 14.4 0.3 21 6.1 0.0 3.3 4 0 0 4 4 4 0 Ankyrin repeat Ank_4 PF13637.6 EST43626.1 - 0.071 13.7 0.2 0.42 11.2 0.1 2.1 2 0 0 2 2 2 0 Ankyrin repeats (many copies) DUF1439 PF07273.12 EST43628.1 - 0.021 14.6 1.7 0.37 10.6 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1439) WW PF00397.26 EST43628.1 - 0.074 13.2 1.4 0.35 11.0 1.4 2.2 1 1 0 1 1 1 0 WW domain NYD-SP28_assoc PF14775.6 EST43631.1 - 0.0066 16.5 3.1 0.0066 16.5 3.1 7.6 8 1 0 8 8 8 1 Sperm tail C-terminal domain HALZ PF02183.18 EST43631.1 - 0.022 15.0 0.4 0.022 15.0 0.4 10.7 12 0 0 12 12 12 0 Homeobox associated leucine zipper Sec1 PF00995.23 EST43632.1 - 4.3e-11 42.8 20.8 4.1e-09 36.2 20.8 2.9 1 1 0 1 1 1 1 Sec1 family DUF4061 PF13270.6 EST43632.1 - 0.0077 16.5 0.2 0.026 14.8 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4061) DUF5545 PF17699.1 EST43633.1 - 0.078 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5545) DUF695 PF05117.12 EST43635.1 - 0.036 14.2 0.0 0.037 14.2 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF695) MDFI PF15316.6 EST43636.1 - 0.037 14.1 0.1 0.11 12.6 0.1 1.8 1 0 0 1 1 1 0 MyoD family inhibitor Plasmid_parti PF01672.16 EST43636.1 - 0.088 13.5 1.9 0.45 11.2 0.7 2.6 2 0 0 2 2 2 0 Putative plasmid partition protein GalKase_gal_bdg PF10509.9 EST43637.1 - 3.3e-11 42.6 0.0 7.3e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 EST43637.1 - 0.00011 22.4 0.1 0.00028 21.2 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal CSN8_PSD8_EIF3K PF10075.9 EST43637.1 - 0.05 13.6 0.1 0.19 11.7 0.1 1.9 1 1 0 1 1 1 0 CSN8/PSMD8/EIF3K family CAP_C PF08603.11 EST43640.1 - 3.5e-32 111.2 4.9 3.5e-32 111.2 4.9 2.1 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) C terminal CAP_N PF01213.19 EST43640.1 - 4.3e-12 46.1 2.4 1.6e-11 44.3 2.4 1.8 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal TBCC PF07986.12 EST43640.1 - 2.1e-06 27.5 6.2 4.3e-06 26.5 6.2 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C Androgen_recep PF02166.16 EST43640.1 - 3.5 6.4 6.0 5.1 5.8 6.0 1.2 1 0 0 1 1 1 0 Androgen receptor XPG_I PF00867.18 EST43641.1 - 4.1e-13 49.5 0.1 1.1e-12 48.1 0.1 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EST43641.1 - 2.7e-08 34.2 0.1 7.9e-08 32.7 0.0 1.8 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I_2 PF12813.7 EST43641.1 - 1e-06 28.4 0.0 1.7e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing NDC10_II PF16787.5 EST43642.1 - 0.00086 18.4 1.1 0.0012 17.9 1.1 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 RWD PF05773.22 EST43643.1 - 3.2e-07 30.6 1.4 3.2e-07 30.6 1.4 2.1 2 2 0 2 2 2 1 RWD domain TRAPP PF04051.16 EST43645.1 - 8.4e-11 41.8 0.0 1.5e-10 41.0 0.0 1.4 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component TRAPP PF04051.16 EST43646.1 - 9.2e-12 44.9 0.0 1.6e-11 44.2 0.0 1.3 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component Cnn_1N PF07989.11 EST43647.1 - 0.058 13.6 0.6 0.24 11.6 0.6 2.2 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 Pkinase PF00069.25 EST43649.1 - 1.5e-56 191.7 0.1 3.9e-31 108.4 0.1 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EST43649.1 - 1.1e-24 87.1 0.0 4.9e-24 85.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EST43649.1 - 0.0007 19.6 0.0 0.0011 18.9 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EST43649.1 - 0.043 13.4 3.9 0.11 12.0 0.9 2.8 2 1 0 2 2 2 0 Choline/ethanolamine kinase DNA_ligase_A_M PF01068.21 EST43649.1 - 0.096 12.3 0.9 0.21 11.2 0.1 1.8 2 0 0 2 2 2 0 ATP dependent DNA ligase domain Cnn_1N PF07989.11 EST43651.1 - 0.058 13.6 0.6 0.24 11.6 0.6 2.2 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 TRAPP PF04051.16 EST43652.1 - 9.2e-12 44.9 0.0 1.6e-11 44.2 0.0 1.3 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component Trypan_PARP PF05887.11 EST43653.1 - 0.0092 16.0 31.6 0.11 12.5 17.5 2.3 1 1 1 2 2 2 2 Procyclic acidic repetitive protein (PARP) JIP_LZII PF16471.5 EST43653.1 - 0.023 14.8 0.9 0.023 14.8 0.9 6.0 3 1 1 5 5 5 0 JNK-interacting protein leucine zipper II Zot PF05707.12 EST43653.1 - 0.61 9.7 3.9 2.4 7.7 0.1 2.9 2 1 1 3 3 3 0 Zonular occludens toxin (Zot) Spc7 PF08317.11 EST43653.1 - 3 6.6 52.0 0.24 10.3 11.7 3.4 1 1 3 4 4 4 0 Spc7 kinetochore protein Neisseria_TspB PF05616.13 EST43653.1 - 4.1 5.8 6.4 7.3 5.0 6.4 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein LPP PF04728.13 EST43653.1 - 8.3 6.9 19.6 42 4.6 0.1 5.7 5 1 0 5 5 5 0 Lipoprotein leucine-zipper CCDC53 PF10152.9 EST43654.1 - 0.00075 19.9 0.0 0.00084 19.8 0.0 1.2 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex ThiF PF00899.21 EST43655.1 - 4.8e-36 124.3 0.5 5.9e-36 124.0 0.5 1.0 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 EST43655.1 - 5.4e-05 23.5 3.5 0.00034 20.9 3.1 2.1 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 EST43655.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_3 PF03447.16 EST43655.1 - 1.2 9.8 3.9 5.5 7.7 3.4 2.2 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DUF21 PF01595.20 EST43656.1 - 7.6e-33 113.7 0.8 1.2e-32 113.0 0.8 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 EST43656.1 - 6.1e-08 33.0 0.0 0.0043 17.5 0.0 2.5 2 0 0 2 2 2 2 CBS domain Tfb5 PF06331.12 EST43657.1 - 0.024 14.6 0.6 0.03 14.3 0.6 1.2 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 Nup54_C PF18437.1 EST43657.1 - 0.064 13.2 1.5 0.085 12.8 0.0 1.8 2 0 0 2 2 2 0 Nup54 C-terminal interacting domain Swm2 PF17083.5 EST43658.1 - 0.011 15.8 1.8 0.013 15.5 1.8 1.1 1 0 0 1 1 1 0 Nucleolar protein Swm2 GAS PF13851.6 EST43658.1 - 0.02 14.3 10.3 0.31 10.4 4.8 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 EST43658.1 - 0.022 15.3 6.3 0.027 15.0 6.3 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF3450 PF11932.8 EST43658.1 - 0.025 13.9 7.2 0.027 13.8 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF2968 PF11180.8 EST43658.1 - 0.18 11.5 6.8 0.22 11.1 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF1759 PF03564.15 EST43658.1 - 0.24 11.3 3.4 3.5 7.5 3.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) BRE1 PF08647.11 EST43658.1 - 0.37 10.9 10.6 0.84 9.8 10.6 1.6 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase bZIP_2 PF07716.15 EST43658.1 - 3.6 7.7 7.5 2.2 8.4 0.3 2.3 2 0 0 2 2 2 0 Basic region leucine zipper PMSR PF01625.21 EST43659.1 - 1.1e-61 207.6 2.5 1.2e-61 207.4 2.5 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase DUF3531 PF12049.8 EST43660.1 - 0.035 14.0 0.8 0.084 12.8 0.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3531) SAPIS-gp6 PF16722.5 EST43661.1 - 0.045 14.1 0.2 0.072 13.5 0.2 1.3 1 0 0 1 1 1 0 Pathogenicity island protein gp6 in Staphylococcus KASH_CCD PF14662.6 EST43661.1 - 0.062 13.1 0.1 0.085 12.7 0.1 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH zf-C3HC4_3 PF13920.6 EST43662.1 - 0.00025 20.8 15.8 0.00025 20.8 15.8 3.9 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_2 PF12756.7 EST43662.1 - 0.022 15.1 3.8 0.022 15.1 3.8 4.4 3 2 1 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 EST43662.1 - 0.07 13.6 0.2 0.07 13.6 0.2 5.4 7 0 0 7 7 7 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EST43662.1 - 0.1 13.5 0.1 0.1 13.5 0.1 6.9 8 1 1 9 9 9 0 C2H2-type zinc finger V-SNARE PF05008.15 EST43662.1 - 0.37 11.2 7.7 3.9 7.9 1.3 2.7 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus zf-C2H2_3rep PF18868.1 EST43662.1 - 0.62 10.7 15.2 1.7 9.3 0.2 4.1 1 1 2 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-H2C2_2 PF13465.6 EST43662.1 - 4 8.0 10.2 12 6.5 0.1 4.1 2 1 0 2 2 2 0 Zinc-finger double domain Kinesin_assoc PF16183.5 EST43663.1 - 0.08 13.1 0.0 0.2 11.8 0.0 1.5 1 1 0 1 1 1 0 Kinesin-associated UPF0020 PF01170.18 EST43666.1 - 1.4e-13 51.0 0.1 3.3e-12 46.5 0.1 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 MTS PF05175.14 EST43666.1 - 0.0045 16.5 0.0 0.021 14.4 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase small domain N6_N4_Mtase PF01555.18 EST43666.1 - 0.01 15.6 0.0 0.039 13.7 0.0 1.9 2 0 0 2 2 2 0 DNA methylase Methyltransf_31 PF13847.6 EST43666.1 - 0.017 14.9 0.0 0.038 13.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MethyltransfD12 PF02086.15 EST43666.1 - 0.039 13.6 1.6 0.21 11.2 0.0 2.6 2 1 0 3 3 3 0 D12 class N6 adenine-specific DNA methyltransferase N6-adenineMlase PF10237.9 EST43666.1 - 0.068 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase Arf PF00025.21 EST43667.1 - 4.7e-31 107.6 0.0 7.7e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EST43667.1 - 1.6e-13 50.6 0.5 2.8e-13 49.8 0.1 1.5 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EST43667.1 - 1.6e-11 44.4 0.0 2.9e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EST43667.1 - 3.6e-09 36.3 0.7 1.2e-08 34.6 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EST43667.1 - 8.3e-09 35.5 0.0 1.8e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 EST43667.1 - 1.4e-07 31.0 4.2 0.00012 21.4 3.4 2.5 1 1 1 2 2 2 2 G-protein alpha subunit FeoB_N PF02421.18 EST43667.1 - 0.026 14.0 0.0 0.26 10.8 0.0 2.4 2 1 1 3 3 3 0 Ferrous iron transport protein B NPR3 PF03666.13 EST43667.1 - 0.036 12.9 0.9 0.055 12.3 0.9 1.4 1 1 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 LRS4 PF10422.9 EST43667.1 - 0.31 10.6 5.8 1.5 8.4 1.8 2.1 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 Ion_trans_2 PF07885.16 EST43669.1 - 1.4e-14 53.8 5.7 1.4e-14 53.8 5.7 2.9 2 1 2 4 4 4 1 Ion channel Mcp5_PH PF12814.7 EST43669.1 - 0.11 12.6 0.1 0.31 11.2 0.0 1.7 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology Ribosomal_L5 PF00281.19 EST43670.1 - 0.15 12.4 0.3 0.4 11.1 0.3 1.6 1 0 0 1 1 1 0 Ribosomal protein L5 UNC-50 PF05216.13 EST43672.1 - 0.08 12.5 5.1 0.13 11.8 5.0 1.4 1 1 0 1 1 1 0 UNC-50 family SLIDE PF09111.10 EST43673.1 - 0.011 15.7 0.3 5.3 7.1 0.1 2.1 2 0 0 2 2 2 0 SLIDE Endotoxin_N PF03945.14 EST43673.1 - 0.025 14.3 0.9 0.032 14.0 0.5 1.4 1 1 0 1 1 1 0 delta endotoxin, N-terminal domain SapB_1 PF05184.15 EST43673.1 - 0.14 12.2 0.7 0.27 11.3 0.7 1.5 1 0 0 1 1 1 0 Saposin-like type B, region 1 SCVP PF17619.2 EST43673.1 - 1.2 10.1 4.5 9.6 7.1 1.5 2.2 1 1 1 2 2 2 0 Secreted clade V proteins Bac_DNA_binding PF00216.21 EST43675.1 - 0.00075 19.7 0.1 0.093 12.9 0.0 2.6 2 0 0 2 2 2 2 Bacterial DNA-binding protein HU-CCDC81_euk_2 PF18289.1 EST43675.1 - 0.01 16.0 0.2 0.78 9.9 0.1 2.8 2 0 0 2 2 2 0 CCDC81 eukaryotic HU domain 2 zf-C2H2_3rep PF18868.1 EST43678.1 - 0.0095 16.6 1.1 0.0095 16.6 1.1 5.4 4 1 1 5 5 5 1 Zinc finger C2H2-type, 3 repeats zf-C3HC4_3 PF13920.6 EST43678.1 - 0.74 9.7 30.2 0.065 13.1 13.8 4.2 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Choline_kinase PF01633.20 EST43679.1 - 5e-23 81.8 9.3 5e-23 81.8 9.3 1.8 1 1 1 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 EST43679.1 - 3.1e-17 63.3 0.0 4.4e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Bromodomain PF00439.25 EST43680.1 - 3.1e-10 40.0 0.2 8.8e-10 38.5 0.2 1.9 1 0 0 1 1 1 1 Bromodomain zf-ZPR1 PF03367.13 EST43682.1 - 5.5e-92 305.8 0.5 3.8e-47 160.1 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain zf-CCHC_6 PF15288.6 EST43682.1 - 0.17 11.8 0.3 0.5 10.3 0.3 1.8 1 0 0 1 1 1 0 Zinc knuckle zinc-ribbons_6 PF07191.12 EST43682.1 - 0.26 11.3 4.5 0.5 10.4 0.3 2.5 2 1 0 2 2 2 0 zinc-ribbons C1_1 PF00130.22 EST43682.1 - 9.4 6.2 6.2 23 4.9 0.8 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Metallophos PF00149.28 EST43683.1 - 1.7e-15 58.1 0.3 2.1e-15 57.8 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Bromodomain PF00439.25 EST43684.1 - 1.4e-09 37.9 0.0 2.5e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Bromodomain UFC1 PF08694.11 EST43685.1 - 0.43 10.2 3.7 0.37 10.4 0.5 2.4 2 0 0 2 2 2 0 Ubiquitin-fold modifier-conjugating enzyme 1 CECR6_TMEM121 PF14997.6 EST43686.1 - 0.0022 17.8 0.0 0.0049 16.7 0.0 1.6 1 0 0 1 1 1 1 CECR6/TMEM121 family AAA_16 PF13191.6 EST43686.1 - 0.017 15.5 0.0 0.04 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain DUF4509 PF14970.6 EST43686.1 - 0.32 10.9 3.9 3.2 7.6 0.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4509) zf-C2H2 PF00096.26 EST43688.1 - 2e-16 59.4 36.7 2.1e-07 31.0 0.1 5.1 5 1 0 5 5 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EST43688.1 - 8.5e-14 51.3 25.6 1.2e-07 31.9 0.5 5.3 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EST43688.1 - 1.1e-11 44.5 33.7 0.0018 19.0 1.9 5.0 5 1 0 5 5 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EST43688.1 - 5.2e-09 36.2 20.9 0.01 16.1 0.7 4.4 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EST43688.1 - 5.2e-07 29.8 23.4 0.0065 16.8 1.1 4.4 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 EST43688.1 - 0.00094 19.4 9.4 0.0027 18.0 1.0 2.7 1 1 3 4 4 4 2 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 EST43688.1 - 0.0076 16.2 22.2 0.029 14.4 0.9 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger DUF4764 PF15961.5 EST43688.1 - 0.011 14.5 0.9 0.011 14.5 0.9 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4764) zf-C2H2_11 PF16622.5 EST43688.1 - 0.014 15.2 23.7 0.23 11.2 0.0 4.8 4 1 1 5 5 4 0 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 EST43688.1 - 0.054 13.6 13.8 0.87 9.8 1.8 3.8 2 1 1 3 3 3 0 Zinc ribbon domain zf-C2H2_2 PF12756.7 EST43688.1 - 0.057 13.8 18.2 2.8 8.3 1.1 4.1 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) BHD_1 PF10403.9 EST43688.1 - 0.06 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 1 zf_UBZ PF18439.1 EST43688.1 - 0.11 12.1 15.8 3.4 7.3 0.3 4.6 4 1 0 4 4 4 0 Ubiquitin-Binding Zinc Finger BolA PF01722.18 EST43688.1 - 0.14 12.5 2.0 1.4 9.2 0.3 2.9 1 1 2 3 3 3 0 BolA-like protein zf-C2H2_9 PF16293.5 EST43688.1 - 1.1 9.1 7.1 6.7 6.6 0.2 3.4 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) LIM PF00412.22 EST43688.1 - 1.8 8.9 24.5 0.23 11.7 4.7 4.1 2 1 2 4 4 3 0 LIM domain zf-C2HE PF16278.5 EST43688.1 - 2.9 8.4 19.2 2 8.9 1.2 4.2 1 1 3 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger Metalloenzyme PF01676.18 EST43689.1 - 9.4e-13 48.1 0.0 1.5e-12 47.4 0.0 1.4 1 1 0 1 1 1 1 Metalloenzyme superfamily PhosphMutase PF10143.9 EST43689.1 - 1.7e-10 41.0 0.0 2.7e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase E2F_TDP PF02319.20 EST43690.1 - 2.3e-06 27.5 1.3 0.0042 17.1 0.0 2.4 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain Acetyltransf_1 PF00583.25 EST43693.1 - 4.8e-15 55.8 0.0 6e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EST43693.1 - 5.7e-09 36.0 0.0 6.6e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EST43693.1 - 6.2e-09 36.2 0.0 8.4e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EST43693.1 - 5.8e-07 29.4 0.0 7.5e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EST43693.1 - 0.0041 17.2 0.1 0.015 15.4 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF771 PF05595.11 EST43695.1 - 0.016 15.2 0.9 0.016 15.2 0.9 4.1 4 1 1 5 5 5 0 Domain of unknown function (DUF771) Nucleoporin2 PF04096.14 EST43696.1 - 0.021 14.9 0.1 0.06 13.5 0.0 1.9 1 1 0 1 1 1 0 Nucleoporin autopeptidase ThiF PF00899.21 EST43697.1 - 1.2e-71 241.0 0.0 1.5e-54 185.0 0.1 2.9 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 EST43697.1 - 7e-46 157.2 7.2 7e-46 157.2 7.2 2.3 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 EST43697.1 - 3e-10 40.7 0.0 3e-10 40.7 0.0 3.1 4 0 0 4 4 4 1 Ubiquitin fold domain E1_4HB PF16191.5 EST43697.1 - 4.1e-05 23.7 2.3 6.4e-05 23.1 0.3 2.5 3 0 0 3 3 3 1 Ubiquitin-activating enzyme E1 four-helix bundle E1_FCCH PF16190.5 EST43697.1 - 0.063 13.5 0.1 0.39 11.0 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin-activating enzyme E1 FCCH domain 2-Hacid_dh_C PF02826.19 EST43697.1 - 0.067 12.5 0.0 2.7 7.3 0.0 2.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain LisH_TPL PF17814.1 EST43698.1 - 3.1e-05 23.5 0.7 0.00023 20.7 0.7 2.6 1 0 0 1 1 1 1 LisH-like dimerisation domain LisH PF08513.11 EST43698.1 - 0.034 14.1 0.2 0.092 12.7 0.2 1.8 1 0 0 1 1 1 0 LisH UTP25 PF06862.12 EST43699.1 - 8.3e-14 51.2 13.6 1.6e-12 46.9 6.4 2.3 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 NFACT-R_2 PF18297.1 EST43699.1 - 0.082 13.1 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 NFACT protein RNA binding domain Recep_L_domain PF01030.24 EST43699.1 - 0.38 10.9 6.9 0.14 12.3 0.5 3.0 2 1 1 3 3 3 0 Receptor L domain Helicase_C PF00271.31 EST43699.1 - 1.4 9.3 4.0 1.5 9.2 0.3 2.4 2 0 0 2 2 2 0 Helicase conserved C-terminal domain DUF2730 PF10805.8 EST43700.1 - 0.087 12.9 1.6 0.13 12.3 0.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Med7 PF05983.11 EST43700.1 - 0.6 10.2 5.1 0.79 9.8 5.1 1.4 1 1 0 1 1 1 0 MED7 protein COG5 PF10392.9 EST43701.1 - 0.011 15.9 11.1 0.011 15.9 11.1 7.0 3 2 2 7 7 7 0 Golgi transport complex subunit 5 Pkinase PF00069.25 EST43702.1 - 3e-47 161.2 0.0 3.7e-47 160.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST43702.1 - 6.9e-32 110.7 0.0 8.1e-32 110.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EST43702.1 - 5.5e-10 38.6 0.0 7.3e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EST43702.1 - 0.00077 18.9 0.1 0.0022 17.4 0.1 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EST43702.1 - 0.0096 15.3 0.1 0.093 12.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EST43702.1 - 0.19 11.6 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RNase_HII PF01351.18 EST43703.1 - 8.6e-40 136.7 0.0 1.1e-39 136.3 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII Ribosomal_S3Ae PF01015.18 EST43703.1 - 0.029 14.0 0.1 0.049 13.2 0.1 1.4 1 0 0 1 1 1 0 Ribosomal S3Ae family XPG_I_2 PF12813.7 EST43703.1 - 0.05 13.1 0.2 0.069 12.6 0.2 1.2 1 0 0 1 1 1 0 XPG domain containing DIX PF00778.17 EST43704.1 - 0.018 14.9 0.3 2.8 7.8 0.0 2.5 1 1 0 2 2 2 0 DIX domain UCH PF00443.29 EST43705.1 - 1.6e-32 113.0 15.9 5.3e-32 111.3 15.9 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EST43705.1 - 0.00011 21.8 11.0 0.00087 18.8 11.0 2.3 1 1 0 1 1 1 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase UCH_1 PF13423.6 EST43705.1 - 0.0003 20.5 15.4 0.0086 15.7 7.5 2.4 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase THUMP PF02926.17 EST43706.1 - 0.0067 16.5 0.1 0.025 14.7 0.1 1.9 1 1 0 1 1 1 1 THUMP domain V_ATPase_I PF01496.19 EST43707.1 - 1.2e-190 635.4 24.7 2.3e-139 465.8 13.1 2.0 1 1 1 2 2 2 2 V-type ATPase 116kDa subunit family DUF2458 PF10454.9 EST43707.1 - 0.33 10.6 1.8 0.22 11.1 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) VF530 PF09905.9 EST43708.1 - 0.026 14.7 1.4 2.4 8.4 0.2 3.8 3 0 0 3 3 3 0 DNA-binding protein VF530 DUF4347 PF14252.6 EST43708.1 - 1.2 9.0 6.0 3.1 7.6 1.7 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4347) UQ_con PF00179.26 EST43709.1 - 1.8e-15 56.8 0.6 2.4e-15 56.4 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Cep57_MT_bd PF06657.13 EST43710.1 - 0.0052 17.2 0.4 0.012 16.1 0.4 1.6 1 0 0 1 1 1 1 Centrosome microtubule-binding domain of Cep57 GCP_N_terminal PF17681.1 EST43712.1 - 1.4e-09 38.0 7.8 6.7e-09 35.8 6.4 2.6 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EST43712.1 - 0.0001 21.9 3.7 0.0001 21.9 3.7 3.1 2 2 2 4 4 4 2 Gamma tubulin complex component C-terminal SelK_SelG PF10961.8 EST43712.1 - 0.17 12.6 1.9 3.6 8.3 0.3 2.5 2 0 0 2 2 2 0 Selenoprotein SelK_SelG DNA_pol_A_exo1 PF01612.20 EST43714.1 - 0.019 14.7 0.3 0.036 13.8 0.3 1.4 1 0 0 1 1 1 0 3'-5' exonuclease Baculo_FP PF03258.14 EST43714.1 - 0.09 12.9 0.6 0.17 12.1 0.1 1.7 2 0 0 2 2 2 0 Baculovirus FP protein Ribosomal_L22e PF01776.17 EST43714.1 - 0.83 10.1 6.8 4.7 7.6 1.0 2.8 2 1 1 3 3 3 0 Ribosomal L22e protein family CHASE9 PF17153.4 EST43715.1 - 0.025 14.7 1.0 0.025 14.7 1.0 1.5 2 0 0 2 2 2 0 Periplasmic sensor domain, extracellular PilO PF04350.13 EST43715.1 - 0.081 13.1 2.2 0.13 12.4 2.2 1.4 1 0 0 1 1 1 0 Pilus assembly protein, PilO LMSTEN PF07988.12 EST43717.1 - 0.088 12.3 0.1 0.24 10.9 0.1 1.7 1 0 0 1 1 1 0 LMSTEN motif Pkinase PF00069.25 EST43719.1 - 2.4e-75 253.3 0.0 2.7e-75 253.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST43719.1 - 6.8e-34 117.3 0.0 8.5e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EST43719.1 - 0.00054 20.0 0.0 0.0032 17.4 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 EST43719.1 - 0.062 12.3 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Haspin_kinase PF12330.8 EST43719.1 - 0.067 12.1 0.0 0.72 8.7 0.0 2.0 1 1 0 1 1 1 0 Haspin like kinase domain 5_nucleotid PF05761.14 EST43721.1 - 7.7e-111 371.2 11.6 9.4e-111 370.9 11.6 1.0 1 0 0 1 1 1 1 5' nucleotidase family Lipoprotein_22 PF17294.2 EST43721.1 - 0.036 13.7 0.4 0.19 11.3 0.2 2.3 2 0 0 2 2 2 0 Uncharacterised lipoprotein family ABC_tran_CTD PF16326.5 EST43721.1 - 0.038 14.2 0.9 0.1 12.9 0.9 1.7 1 0 0 1 1 1 0 ABC transporter C-terminal domain Hydrolase PF00702.26 EST43721.1 - 0.11 12.8 0.0 0.79 10.0 0.0 2.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase KASH_CCD PF14662.6 EST43721.1 - 1.1 9.1 6.9 0.19 11.6 3.1 1.6 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH LRR_6 PF13516.6 EST43722.1 - 1.9e-07 30.6 0.3 0.34 11.1 0.0 5.0 4 0 0 4 4 4 3 Leucine Rich repeat LRR_4 PF12799.7 EST43722.1 - 0.00034 20.9 10.6 0.14 12.7 0.0 5.5 5 2 0 5 5 5 2 Leucine Rich repeats (2 copies) FAM167 PF11652.8 EST43724.1 - 2.2 8.8 9.8 0.46 11.0 2.3 3.3 2 1 0 2 2 2 0 FAM167 TPR_2 PF07719.17 EST43725.1 - 5.5e-34 113.5 20.6 6.1e-05 22.8 0.4 9.4 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_1 PF00515.28 EST43725.1 - 7.7e-33 111.0 30.1 1.9e-06 27.4 0.0 9.6 9 1 0 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.6 EST43725.1 - 1.8e-22 79.4 11.5 1.8e-07 31.3 0.2 6.8 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 EST43725.1 - 3.4e-21 73.6 21.6 0.0028 17.8 0.1 8.7 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.6 EST43725.1 - 1.4e-18 66.3 26.3 5.4e-08 32.4 1.5 7.6 7 2 2 9 9 8 4 TPR repeat STI1 PF17830.1 EST43725.1 - 1.2e-16 60.4 19.8 5.1e-13 48.7 8.6 3.0 2 0 0 2 2 2 2 STI1 domain TPR_16 PF13432.6 EST43725.1 - 2.7e-16 59.9 0.3 0.00059 20.4 0.0 6.2 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 EST43725.1 - 9.6e-13 47.2 7.9 0.0022 17.9 0.1 6.8 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 EST43725.1 - 1.6e-12 47.2 3.0 2.1 9.4 0.0 7.7 6 3 3 9 9 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 EST43725.1 - 4e-12 46.5 10.7 0.0045 17.5 0.0 6.5 5 2 1 6 6 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 EST43725.1 - 2.9e-11 42.8 4.0 0.01 15.7 0.0 6.4 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 EST43725.1 - 2.5e-09 36.9 15.9 0.0049 17.2 0.3 8.0 8 1 0 8 8 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EST43725.1 - 3.8e-09 36.6 13.6 0.033 14.4 0.8 4.9 3 2 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EST43725.1 - 1.6e-08 34.6 15.2 2.8 8.8 0.1 8.2 8 0 0 8 8 8 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EST43725.1 - 7.1e-05 22.8 4.0 0.14 12.3 0.0 5.2 5 1 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 EST43725.1 - 0.00084 19.4 0.0 0.12 12.5 0.0 3.8 4 1 0 4 4 3 1 Tetratricopeptide repeat XPC-binding PF09280.11 EST43725.1 - 0.0056 16.4 10.5 0.013 15.3 3.4 3.9 4 0 0 4 4 4 1 XPC-binding domain RPN7 PF10602.9 EST43725.1 - 0.015 15.0 7.3 0.26 11.0 2.8 3.3 2 2 0 2 2 2 0 26S proteasome subunit RPN7 NRBF2_MIT PF17169.4 EST43725.1 - 0.023 14.9 5.6 1.2 9.4 0.6 4.9 5 1 0 5 5 4 0 MIT domain of nuclear receptor-binding factor 2 TPR_20 PF14561.6 EST43725.1 - 0.045 14.1 6.6 0.67 10.3 0.0 4.7 4 2 2 6 6 5 0 Tetratricopeptide repeat HHH_8 PF14716.6 EST43725.1 - 0.094 13.1 0.7 1.7 9.1 0.1 3.4 3 0 0 3 3 3 0 Helix-hairpin-helix domain TPR_5 PF12688.7 EST43725.1 - 0.11 12.8 0.3 2 8.7 0.0 2.9 3 0 0 3 3 3 0 Tetratrico peptide repeat TPR_15 PF13429.6 EST43725.1 - 0.13 11.5 5.1 0.64 9.2 0.5 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EST43725.1 - 0.13 12.2 16.2 0.064 13.3 4.9 3.8 2 1 1 3 3 3 0 Putative TPR-like repeat DUF5113 PF17140.4 EST43725.1 - 0.16 11.7 4.4 15 5.3 0.1 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF5113) NSF PF02071.20 EST43725.1 - 1 10.4 4.1 1.2e+02 4.2 0.2 4.5 3 0 0 3 3 3 0 Aromatic-di-Alanine (AdAR) repeat MIT PF04212.18 EST43725.1 - 1.3 9.2 21.7 0.18 11.9 1.9 5.2 7 0 0 7 7 6 0 MIT (microtubule interacting and transport) domain Alkyl_sulf_dimr PF14863.6 EST43725.1 - 2.7 8.5 5.9 28 5.2 0.2 3.2 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation Aminotran_5 PF00266.19 EST43726.1 - 1.2e-43 149.6 0.0 3.2e-42 144.8 0.0 2.6 1 1 0 1 1 1 1 Aminotransferase class-V AIRS_C PF02769.22 EST43726.1 - 1.8e-16 60.7 0.0 4.7e-16 59.3 0.0 1.7 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 EST43726.1 - 4.9e-15 56.0 0.1 1.7e-14 54.2 0.1 2.0 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Aminotran_1_2 PF00155.21 EST43726.1 - 0.00036 19.8 0.0 0.00068 18.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II UCH PF00443.29 EST43728.1 - 1.2e-38 133.2 5.6 3.6e-38 131.5 5.6 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EST43728.1 - 1.4e-08 34.7 3.6 4.9e-05 23.1 0.2 2.1 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF4821 PF16092.5 EST43729.1 - 2.2e-20 73.4 0.0 2.5e-17 63.4 0.0 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF4821) Adaptin_binding PF10199.9 EST43729.1 - 7.5 7.2 10.8 34 5.1 0.0 2.9 3 0 0 3 3 3 0 Alpha and gamma adaptin binding protein p34 Ank_2 PF12796.7 EST43733.1 - 1.4e-14 54.4 7.0 1.6e-09 38.2 0.3 3.5 2 2 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 EST43733.1 - 5.3e-11 42.5 1.0 0.0065 16.9 0.1 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EST43733.1 - 9.2e-11 41.8 3.7 0.00086 19.6 0.1 3.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EST43733.1 - 1.7e-10 40.2 1.5 0.072 13.7 0.1 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 EST43733.1 - 1e-08 35.5 3.0 4.4e-05 24.0 0.2 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) TetR_C_4 PF08359.11 EST43733.1 - 2.7 8.1 13.7 1.9 8.7 3.5 3.5 1 1 2 3 3 3 0 YsiA-like protein, C-terminal region AA_kinase PF00696.28 EST43735.1 - 2.2e-23 83.1 0.4 5e-23 82.0 0.4 1.5 1 1 0 1 1 1 1 Amino acid kinase family VSP PF03302.13 EST43738.1 - 4.8e-16 58.6 305.6 0.00054 18.9 23.8 12.0 1 1 8 10 10 10 9 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST43738.1 - 1.7e-07 31.4 284.9 0.0018 18.4 24.9 13.1 1 1 11 13 13 13 9 Furin-like repeat, cysteine-rich Podoplanin PF05808.11 EST43738.1 - 0.43 10.7 4.6 1.3 9.1 4.6 1.7 1 0 0 1 1 1 0 Podoplanin DUF1294 PF06961.13 EST43741.1 - 0.076 13.3 0.4 1.1 9.5 0.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1294) LMBR1 PF04791.16 EST43746.1 - 4e-15 55.7 57.0 3.8e-14 52.5 57.8 2.1 1 1 1 2 2 2 1 LMBR1-like membrane protein dsDNA_bind PF01984.20 EST43747.1 - 8.1e-21 74.4 5.1 9.5e-21 74.2 5.1 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain XPG_I PF00867.18 EST43748.1 - 9.1e-09 35.6 1.9 2.8e-08 34.0 0.8 2.5 2 0 0 2 2 2 1 XPG I-region XPG_I_2 PF12813.7 EST43748.1 - 0.044 13.2 0.1 0.077 12.5 0.1 1.4 1 0 0 1 1 1 0 XPG domain containing XPG_I PF00867.18 EST43750.1 - 1e-10 41.8 1.0 2.3e-09 37.5 0.2 2.6 2 0 0 2 2 2 1 XPG I-region DASH_Ask1 PF08655.10 EST43750.1 - 0.075 12.9 0.1 0.24 11.3 0.1 1.8 1 0 0 1 1 1 0 DASH complex subunit Ask1 NDUF_B6 PF09782.9 EST43750.1 - 0.2 11.8 0.6 0.47 10.6 0.0 1.9 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit OCD_Mu_crystall PF02423.15 EST43751.1 - 1.6e-56 191.6 2.3 1.9e-56 191.3 2.3 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 EST43751.1 - 7.1e-09 35.8 0.1 1.2e-08 35.1 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 EST43751.1 - 0.00012 21.4 0.8 0.0002 20.7 0.8 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Glu_dehyd_C PF16912.5 EST43751.1 - 0.00079 19.0 0.1 0.0012 18.4 0.1 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AdoHcyase_NAD PF00670.21 EST43751.1 - 0.0054 16.8 1.1 0.012 15.7 0.7 1.8 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain VSP PF03302.13 EST43760.1 - 1.4e-16 60.4 304.7 3.2e-06 26.3 31.5 11.2 1 1 8 9 9 9 8 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST43760.1 - 0.00041 20.5 293.2 0.01 16.0 25.0 13.8 1 1 11 13 13 13 8 Furin-like repeat, cysteine-rich Podoplanin PF05808.11 EST43760.1 - 0.35 11.0 4.6 1.3 9.1 4.6 1.9 1 0 0 1 1 1 0 Podoplanin Herpes_LAMP2 PF06126.11 EST43761.1 - 0.063 11.9 0.1 0.068 11.8 0.1 1.0 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 PRP38 PF03371.15 EST43762.1 - 0.06 13.2 0.0 0.24 11.2 0.0 2.0 2 1 0 2 2 2 0 PRP38 family MFS_1 PF07690.16 EST43763.1 - 1.5e-19 70.2 37.8 1.5e-19 70.2 37.8 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Protocadherin PF08374.11 EST43763.1 - 0.61 10.0 1.8 5.3 7.0 0.1 2.8 3 0 0 3 3 3 0 Protocadherin Geminin PF07412.12 EST43765.1 - 0.00097 18.9 2.6 0.0022 17.7 2.8 1.6 1 1 0 1 1 1 1 Geminin Polbeta PF18765.1 EST43765.1 - 0.068 13.3 0.8 0.49 10.5 0.3 2.4 1 1 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase TnpV PF14198.6 EST43765.1 - 0.29 11.1 4.5 0.27 11.2 2.7 1.9 2 1 0 2 2 2 0 Transposon-encoded protein TnpV FapA PF03961.13 EST43765.1 - 0.49 8.9 4.8 0.7 8.4 4.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Snapin_Pallidin PF14712.6 EST43765.1 - 0.86 10.1 8.8 2.8 8.4 5.5 2.4 1 1 1 2 2 2 0 Snapin/Pallidin CLN3 PF02487.17 EST43766.1 - 6.7e-58 196.6 12.3 7.6e-58 196.5 12.3 1.0 1 0 0 1 1 1 1 CLN3 protein DUF3397 PF11877.8 EST43766.1 - 0.02 15.1 2.4 0.02 15.1 2.4 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3397) DUF4131 PF13567.6 EST43766.1 - 8.8 6.0 10.7 1.8 8.2 2.8 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) TetR_C_23 PF17931.1 EST43768.1 - 0.052 13.7 0.8 0.082 13.0 0.8 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF1525 PF07511.11 EST43768.1 - 0.063 13.4 1.4 0.14 12.3 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1525) C_GCAxxG_C_C PF09719.10 EST43768.1 - 0.073 13.4 0.1 0.13 12.6 0.1 1.3 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) Ribosomal_S21 PF01165.20 EST43768.1 - 0.082 12.6 0.7 0.23 11.2 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein S21 FlaC_arch PF05377.11 EST43768.1 - 0.78 10.2 4.2 6.8 7.2 0.5 2.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF3867 PF12983.7 EST43770.1 - 0.087 12.9 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3867) Xrn1_D3 PF18194.1 EST43772.1 - 0.065 13.3 0.5 0.86 9.7 0.0 3.0 2 0 0 2 2 2 0 Exoribonuclease 1 Domain-3 Forkhead PF00250.18 EST43772.1 - 0.068 13.4 3.6 0.085 13.1 0.4 2.8 3 0 0 3 3 3 0 Forkhead domain DUF2935 PF11155.8 EST43772.1 - 0.15 12.4 8.4 0.25 11.7 0.4 4.1 2 1 1 3 3 3 0 Domain of unknown function (DUF2935) DUF3867 PF12983.7 EST43773.1 - 0.087 12.9 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3867) HSP70 PF00012.20 EST43775.1 - 3.8e-26 91.4 1.2 3.8e-26 91.4 1.2 3.4 2 2 1 3 3 3 1 Hsp70 protein MutL PF13941.6 EST43775.1 - 0.0046 15.6 0.0 0.0098 14.5 0.0 1.4 1 0 0 1 1 1 1 MutL protein MreB_Mbl PF06723.13 EST43775.1 - 0.033 13.0 0.5 0.12 11.2 0.1 2.0 2 0 0 2 2 2 0 MreB/Mbl protein FtsA PF14450.6 EST43775.1 - 1.3 9.5 8.7 0.79 10.2 0.0 4.4 5 2 0 5 5 5 0 Cell division protein FtsA FliG_M PF14841.6 EST43776.1 - 0.037 14.3 0.2 0.066 13.4 0.1 1.5 1 1 0 1 1 1 0 FliG middle domain LANC_like PF05147.13 EST43776.1 - 0.076 11.6 1.1 0.094 11.3 1.1 1.0 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein Presenilin PF01080.17 EST43776.1 - 2.9 6.5 4.3 3.3 6.4 4.3 1.1 1 0 0 1 1 1 0 Presenilin NuDC PF16273.5 EST43776.1 - 5.8 7.5 21.6 0.51 10.9 16.2 1.8 2 0 0 2 2 2 0 Nuclear distribution C domain HA2 PF04408.23 EST43776.1 - 9.7 6.5 8.4 16 5.8 8.4 1.4 1 1 0 1 1 1 0 Helicase associated domain (HA2) CAP PF00188.26 EST43777.1 - 2.5e-05 25.1 0.0 4.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family EGF_3 PF12947.7 EST43778.1 - 9.2e-05 22.6 19.5 0.016 15.4 2.1 2.9 2 1 0 2 2 2 2 EGF domain DUF1043 PF06295.12 EST43778.1 - 0.027 14.5 0.1 0.039 13.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) hEGF PF12661.7 EST43778.1 - 0.031 14.9 1.7 0.031 14.9 1.7 3.9 4 0 0 4 4 4 0 Human growth factor-like EGF Plasmod_Pvs28 PF06247.11 EST43778.1 - 0.053 13.8 25.0 0.89 9.9 9.5 2.9 2 1 0 2 2 2 0 Pvs28 EGF domain EGF_2 PF07974.13 EST43778.1 - 7.8 7.0 27.4 0.13 12.7 8.3 3.5 3 1 0 3 3 3 0 EGF-like domain VSP PF03302.13 EST43779.1 - 9.5e-07 28.0 34.2 9.5e-07 28.0 34.2 2.3 1 1 1 2 2 2 1 Giardia variant-specific surface protein DUF4690 PF15756.5 EST43779.1 - 0.1 13.2 0.2 0.24 12.0 0.2 1.6 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Podoplanin PF05808.11 EST43785.1 - 0.01 16.0 2.9 0.022 14.9 2.9 1.5 1 0 0 1 1 1 0 Podoplanin VSP PF03302.13 EST43785.1 - 7.7 5.2 80.8 4.5 6.0 21.0 4.0 1 1 2 3 3 3 0 Giardia variant-specific surface protein DUF2408 PF10303.9 EST43786.1 - 0.032 14.8 3.9 0.1 13.2 3.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) HTH_10 PF04967.12 EST43787.1 - 0.0012 18.6 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 HTH DNA binding domain Fe_dep_repress PF01325.19 EST43787.1 - 0.039 14.2 0.0 0.063 13.5 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_24 PF13412.6 EST43787.1 - 0.06 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Podoplanin PF05808.11 EST43789.1 - 0.0072 16.4 0.1 0.016 15.3 0.1 1.5 1 0 0 1 1 1 1 Podoplanin Syndecan PF01034.20 EST43789.1 - 0.16 11.9 0.2 0.27 11.2 0.2 1.3 1 0 0 1 1 1 0 Syndecan domain JAMP PF05571.12 EST43790.1 - 0.023 14.4 0.2 0.024 14.3 0.2 1.2 1 0 0 1 1 1 0 JNK1/MAPK8-associated membrane protein TPR_1 PF00515.28 EST43792.1 - 1.6e-19 68.8 10.5 0.00012 21.8 0.1 6.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 EST43792.1 - 3.6e-17 61.0 3.4 0.00055 19.9 0.0 6.5 5 1 1 6 6 6 4 Tetratricopeptide repeat DnaJ PF00226.31 EST43792.1 - 1.5e-11 44.3 0.9 1.5e-11 44.3 0.9 2.2 2 0 0 2 2 2 1 DnaJ domain TPR_19 PF14559.6 EST43792.1 - 1.3e-09 38.4 4.5 0.0006 20.3 0.0 4.8 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EST43792.1 - 2.9e-08 33.9 9.5 0.02 15.2 1.0 6.0 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 EST43792.1 - 6e-08 33.2 1.5 0.00098 19.7 0.0 4.0 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EST43792.1 - 1.4e-06 28.0 13.4 0.13 12.6 0.4 6.7 7 0 0 7 7 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EST43792.1 - 1.2e-05 25.5 1.4 1.2e-05 25.5 1.4 4.2 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EST43792.1 - 0.0011 18.9 0.6 37 4.7 0.2 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 EST43792.1 - 0.0028 17.3 6.3 0.24 11.1 0.1 4.5 3 1 0 3 3 3 1 TPR repeat TPR_14 PF13428.6 EST43792.1 - 0.011 16.5 0.1 16 6.6 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat ArnB_C PF18677.1 EST43792.1 - 0.054 13.6 5.7 0.18 11.9 5.7 2.0 1 0 0 1 1 1 0 Archaellum regulatory network B, C-terminal domain MIT PF04212.18 EST43792.1 - 0.83 9.8 12.2 34 4.6 0.0 4.8 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 EST43792.1 - 2.7 8.8 8.5 1.7e+02 3.2 0.1 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 EST43792.1 - 2.7 7.5 8.1 16 5.0 0.3 4.4 5 0 0 5 5 5 0 SHNi-TPR DUF5492 PF17596.2 EST43793.1 - 4.1 7.8 14.1 2.4 8.6 0.2 3.2 2 1 1 3 3 3 0 Family of unknown function (DUF5492) Proteasome PF00227.26 EST43799.1 - 3.1e-40 137.7 0.4 3.5e-40 137.5 0.4 1.0 1 0 0 1 1 1 1 Proteasome subunit NAD_Gly3P_dh_C PF07479.14 EST43799.1 - 0.065 13.5 0.1 0.48 10.7 0.0 2.1 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus SLC35F PF06027.12 EST43800.1 - 0.0024 17.5 11.8 0.004 16.7 11.8 1.4 1 1 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 EST43800.1 - 0.0089 16.2 27.4 0.013 15.7 5.6 3.0 1 1 2 3 3 3 3 EamA-like transporter family DUF2157 PF09925.9 EST43800.1 - 1.6 8.5 8.0 1.4 8.7 1.0 3.0 2 1 1 3 3 3 0 Predicted membrane protein (DUF2157) CsgF PF10614.9 EST43801.1 - 0.13 12.5 4.2 0.38 11.0 2.9 1.9 2 0 0 2 2 2 0 Type VIII secretion system (T8SS), CsgF protein Podoplanin PF05808.11 EST43802.1 - 0.008 16.3 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 Podoplanin VSP PF03302.13 EST43802.1 - 0.028 13.3 37.3 0.15 10.8 37.3 2.5 1 1 0 1 1 1 0 Giardia variant-specific surface protein Crinivirus_P26 PF07416.11 EST43804.1 - 0.0074 16.0 1.8 0.048 13.4 0.1 2.5 2 1 1 3 3 3 1 Crinivirus P26 protein DUF1318 PF07027.12 EST43804.1 - 0.018 15.5 0.1 0.039 14.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1318) DUF2469 PF10611.9 EST43804.1 - 0.061 13.9 1.2 0.13 12.8 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2469) Ribosomal_L7Ae PF01248.26 EST43806.1 - 2.1e-18 65.9 1.7 3e-18 65.4 1.5 1.4 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SpoU_sub_bind PF08032.12 EST43806.1 - 0.019 15.2 0.2 0.027 14.8 0.2 1.3 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding Hydrolase PF00702.26 EST43806.1 - 0.096 13.0 0.1 0.15 12.3 0.1 1.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF3567 PF12091.8 EST43806.1 - 0.16 12.1 0.1 1.6 8.9 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3567) Ribosomal_L7Ae PF01248.26 EST43807.1 - 8.1e-21 73.6 1.1 1e-20 73.3 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PE PF00934.20 EST43807.1 - 0.032 14.5 0.1 0.046 14.1 0.1 1.2 1 0 0 1 1 1 0 PE family 2-Hacid_dh PF00389.30 EST43807.1 - 0.079 12.6 0.9 0.11 12.2 0.9 1.4 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain TSC22 PF01166.18 EST43809.1 - 0.012 15.9 0.4 0.038 14.3 0.4 1.8 1 0 0 1 1 1 0 TSC-22/dip/bun family MCR_beta_N PF02783.15 EST43809.1 - 0.061 13.0 0.0 0.079 12.6 0.0 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, N-terminal domain Flavodoxin_1 PF00258.25 EST43810.1 - 3.2e-17 63.1 0.6 3.8e-17 62.8 0.6 1.0 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 EST43810.1 - 0.0021 18.3 0.0 0.0025 18.1 0.0 1.3 1 1 0 1 1 1 1 Flavodoxin domain DUF5066 PF16728.5 EST43810.1 - 0.018 14.4 0.0 0.023 14.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5066) Pkinase PF00069.25 EST43813.1 - 7.6e-14 51.7 0.5 1e-13 51.3 0.5 1.1 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 EST43813.1 - 9.6e-14 51.4 0.1 1.3e-13 51.0 0.1 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EST43813.1 - 1.9e-11 44.3 0.0 6.6e-06 26.2 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EST43813.1 - 1.2e-09 37.8 0.0 3.9e-09 36.2 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 EST43813.1 - 1.3e-09 37.7 0.1 1.7e-09 37.3 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 EST43813.1 - 0.00015 21.5 0.4 0.006 16.2 0.2 2.2 1 1 1 2 2 2 2 Choline/ethanolamine kinase EcKinase PF02958.20 EST43813.1 - 0.0011 18.3 0.2 0.0017 17.7 0.2 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Kinase-like PF14531.6 EST43813.1 - 0.0018 17.6 0.2 0.0022 17.3 0.2 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EST43813.1 - 0.027 13.3 0.3 0.032 13.0 0.3 1.2 1 0 0 1 1 1 0 Fungal protein kinase RecO_N PF11967.8 EST43814.1 - 0.076 13.0 0.1 0.26 11.3 0.0 1.9 2 0 0 2 2 2 0 Recombination protein O N terminal Peptidase_C1 PF00112.23 EST43815.1 - 1.2e-14 55.0 0.3 1.6e-14 54.5 0.3 1.2 1 0 0 1 1 1 1 Papain family cysteine protease MORN PF02493.20 EST43817.1 - 3.3e-87 281.4 74.2 1.8e-07 30.6 1.9 14.1 14 0 0 14 14 14 14 MORN repeat DUF3048_C PF17479.2 EST43817.1 - 0.022 15.2 14.7 3.9 7.9 0.9 5.5 2 2 3 5 5 5 0 Protein of unknown function (DUF3048) C-terminal domain ZapB PF06005.12 EST43819.1 - 0.087 13.3 2.8 4.2 7.9 0.1 2.4 2 0 0 2 2 2 0 Cell division protein ZapB Ribosomal_S9 PF00380.19 EST43820.1 - 1.7e-29 102.8 3.1 1.9e-29 102.6 3.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 AntA PF08346.12 EST43821.1 - 0.07 13.7 4.4 3.1 8.4 0.1 3.6 3 0 0 3 3 3 0 AntA/AntB antirepressor DUF3073 PF11273.8 EST43821.1 - 7.7 7.3 10.3 9.5 7.0 3.8 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3073) Flavodoxin_1 PF00258.25 EST43822.1 - 2e-18 67.0 1.3 2.3e-18 66.8 1.3 1.0 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_3 PF12641.7 EST43822.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain Myb_DNA-binding PF00249.31 EST43823.1 - 0.00015 21.8 0.0 0.0003 20.9 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Dpy-30 PF05186.13 EST43824.1 - 1.4e-10 40.7 0.0 3.3e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Dpy-30 motif LIF_OSM PF01291.17 EST43824.1 - 0.056 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 LIF / OSM family DUF1177 PF06675.11 EST43824.1 - 0.22 10.3 0.0 0.39 9.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1177) Adeno_PV PF03910.13 EST43824.1 - 6.7 5.3 9.6 0.84 8.3 0.2 2.9 3 0 0 3 3 3 0 Adenovirus minor core protein PV CD99L2 PF12301.8 EST43826.1 - 0.052 13.8 0.8 0.065 13.5 0.8 1.1 1 0 0 1 1 1 0 CD99 antigen like protein 2 Crinivirus_P26 PF07416.11 EST43828.1 - 0.0016 18.2 1.9 0.015 15.0 0.1 2.5 2 1 1 3 3 3 1 Crinivirus P26 protein DUF1318 PF07027.12 EST43828.1 - 0.029 14.8 0.5 0.06 13.8 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1318) VPS11_C PF12451.8 EST43828.1 - 0.36 11.1 0.1 0.36 11.1 0.1 2.1 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal Ribosomal_L7Ae PF01248.26 EST43829.1 - 2.1e-18 65.9 1.7 3e-18 65.4 1.5 1.4 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SpoU_sub_bind PF08032.12 EST43829.1 - 0.019 15.2 0.2 0.027 14.8 0.2 1.3 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding Hydrolase PF00702.26 EST43829.1 - 0.096 13.0 0.1 0.15 12.3 0.1 1.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF3567 PF12091.8 EST43829.1 - 0.16 12.1 0.1 1.6 8.9 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3567) Peptidase_C1 PF00112.23 EST43831.1 - 1.1e-14 55.0 0.2 1.5e-14 54.6 0.2 1.2 1 0 0 1 1 1 1 Papain family cysteine protease eRF1_3 PF03465.15 EST43832.1 - 0.18 12.3 0.0 0.23 11.9 0.0 1.2 1 0 0 1 1 1 0 eRF1 domain 3 SMC_N PF02463.19 EST43833.1 - 0.0043 16.5 0.2 0.0063 16.0 0.2 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain CobA_CobO_BtuR PF02572.15 EST43833.1 - 0.013 15.8 0.6 0.28 11.4 0.1 1.9 1 1 1 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP ABC_tran PF00005.27 EST43834.1 - 1.8e-48 164.6 0.0 3e-27 95.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EST43834.1 - 2.1e-41 142.4 45.6 2.5e-25 89.7 18.2 2.7 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EST43834.1 - 4.7e-15 55.6 0.2 4.3e-07 29.6 0.2 3.1 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EST43834.1 - 5.1e-06 26.6 0.0 0.068 13.3 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 EST43834.1 - 1.5e-05 25.3 0.0 0.036 14.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 EST43834.1 - 4.7e-05 23.6 0.9 0.0027 17.8 0.0 3.0 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_21 PF13304.6 EST43834.1 - 5.3e-05 23.2 0.0 0.31 10.8 0.1 3.3 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EST43834.1 - 0.00044 20.2 0.1 0.69 9.8 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 EST43834.1 - 0.0006 20.4 5.0 0.5 10.8 0.0 3.2 2 1 1 3 3 3 2 AAA domain AAA_29 PF13555.6 EST43834.1 - 0.00062 19.5 0.1 1.6 8.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain PRK PF00485.18 EST43834.1 - 0.00066 19.5 0.0 0.11 12.3 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EST43834.1 - 0.00074 20.1 0.1 3.5 8.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain TrwB_AAD_bind PF10412.9 EST43834.1 - 0.0015 17.5 0.2 0.073 12.0 0.1 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.6 EST43834.1 - 0.0017 18.7 0.0 0.14 12.6 0.1 2.8 3 0 0 3 3 2 1 AAA ATPase domain AAA_7 PF12775.7 EST43834.1 - 0.0036 16.8 0.0 2.8 7.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing dynein motor region ATP_bind_1 PF03029.17 EST43834.1 - 0.0042 16.9 0.0 0.24 11.1 0.0 2.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 EST43834.1 - 0.013 15.5 0.5 1.5 8.8 0.1 2.7 2 0 0 2 2 2 0 Dynamin family T2SSE PF00437.20 EST43834.1 - 0.03 13.4 0.0 1.2 8.1 0.0 2.8 3 0 0 3 3 3 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 EST43834.1 - 0.038 13.3 0.2 1.9 7.8 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family RRM_occluded PF16842.5 EST43834.1 - 0.053 13.4 0.1 0.13 12.1 0.1 1.7 1 0 0 1 1 1 0 Occluded RNA-recognition motif SbcCD_C PF13558.6 EST43834.1 - 0.095 12.9 0.1 2.3 8.5 0.0 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 EST43834.1 - 0.11 12.9 0.1 24 5.4 0.0 3.1 3 0 0 3 3 2 0 RNA helicase ATP-synt_ab PF00006.25 EST43834.1 - 0.14 11.8 0.1 1.4 8.5 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain TsaE PF02367.17 EST43834.1 - 0.17 11.9 0.1 21 5.1 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Phage_holin_5_1 PF06946.11 EST43835.1 - 0.12 12.8 0.2 0.3 11.5 0.2 1.6 1 0 0 1 1 1 0 Bacteriophage A118-like holin, Hol118 VSP PF03302.13 EST43835.1 - 5.4 5.8 86.7 0.016 14.1 24.2 3.6 1 1 2 3 3 3 0 Giardia variant-specific surface protein NPBW PF15180.6 EST43837.1 - 1 9.2 5.0 8.4 6.3 0.4 2.4 2 0 0 2 2 2 0 Neuropeptides B and W EF-hand_7 PF13499.6 EST43839.1 - 2.6e-18 66.2 1.5 1.2e-11 44.9 0.6 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EST43839.1 - 1.5e-16 58.6 8.1 0.00011 21.5 0.1 3.7 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EST43839.1 - 3.9e-16 57.5 7.9 8.9e-06 25.2 0.2 3.9 3 1 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 EST43839.1 - 8.6e-15 53.5 4.3 1.1e-05 24.6 0.3 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 EST43839.1 - 1.9e-10 40.4 8.3 0.0018 18.1 0.3 3.7 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 EST43839.1 - 9e-07 29.1 0.1 0.00034 20.9 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_10 PF14788.6 EST43839.1 - 4.8e-06 26.3 0.2 0.0063 16.4 0.0 3.3 2 1 1 3 3 3 2 EF hand Caleosin PF05042.13 EST43839.1 - 0.0038 17.2 0.4 0.12 12.3 0.1 2.6 2 1 1 3 3 3 1 Caleosin related protein PaaX PF07848.12 EST43839.1 - 0.041 14.1 0.0 6.4 7.1 0.0 2.3 2 0 0 2 2 2 0 PaaX-like protein Dockerin_1 PF00404.18 EST43839.1 - 0.072 13.3 0.0 4.5 7.5 0.0 2.7 3 0 0 3 3 3 0 Dockerin type I domain SPARC_Ca_bdg PF10591.9 EST43839.1 - 0.087 13.2 0.0 0.77 10.1 0.0 2.0 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DNA_pol3_chi PF04364.13 EST43839.1 - 0.16 12.1 0.0 0.39 10.9 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase III chi subunit, HolC LRR_8 PF13855.6 EST43840.1 - 2.5 7.9 13.4 0.61 9.9 1.0 4.1 3 2 1 4 4 4 0 Leucine rich repeat LRR_1 PF00560.33 EST43840.1 - 4 8.4 5.6 89 4.3 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat EF-hand_7 PF13499.6 EST43841.1 - 2.6e-18 66.2 1.5 1.2e-11 44.9 0.6 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EST43841.1 - 1.5e-16 58.6 8.1 0.00011 21.5 0.1 3.7 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EST43841.1 - 3.9e-16 57.5 7.9 8.9e-06 25.2 0.2 3.9 3 1 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 EST43841.1 - 8.6e-15 53.5 4.3 1.1e-05 24.6 0.3 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 EST43841.1 - 1.9e-10 40.4 8.3 0.0018 18.1 0.3 3.7 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 EST43841.1 - 9e-07 29.1 0.1 0.00034 20.9 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_10 PF14788.6 EST43841.1 - 4.8e-06 26.3 0.2 0.0063 16.4 0.0 3.3 2 1 1 3 3 3 2 EF hand Caleosin PF05042.13 EST43841.1 - 0.0038 17.2 0.4 0.12 12.3 0.1 2.6 2 1 1 3 3 3 1 Caleosin related protein PaaX PF07848.12 EST43841.1 - 0.041 14.1 0.0 6.4 7.1 0.0 2.3 2 0 0 2 2 2 0 PaaX-like protein Dockerin_1 PF00404.18 EST43841.1 - 0.072 13.3 0.0 4.5 7.5 0.0 2.7 3 0 0 3 3 3 0 Dockerin type I domain SPARC_Ca_bdg PF10591.9 EST43841.1 - 0.087 13.2 0.0 0.77 10.1 0.0 2.0 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DNA_pol3_chi PF04364.13 EST43841.1 - 0.16 12.1 0.0 0.39 10.9 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase III chi subunit, HolC NusA_N PF08529.11 EST43842.1 - 0.09 13.1 0.6 0.18 12.2 0.6 1.5 1 0 0 1 1 1 0 NusA N-terminal domain MIR PF02815.19 EST43843.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 MIR domain MFS_1 PF07690.16 EST43844.1 - 3.1e-17 62.6 45.4 3.1e-17 62.6 45.4 2.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Synapsin_C PF02750.14 EST43846.1 - 0.021 14.4 0.1 0.021 14.4 0.1 1.2 1 0 0 1 1 1 0 Synapsin, ATP binding domain Myb_DNA-bind_6 PF13921.6 EST43849.1 - 0.00015 21.9 0.0 0.00019 21.6 0.0 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EST43849.1 - 0.043 14.0 0.0 0.071 13.3 0.0 1.3 1 0 0 1 1 1 0 Myb-like DNA-binding domain SHIPPO-rpt PF07004.12 EST43850.1 - 3.4e-29 100.4 16.8 0.00028 21.7 0.2 6.2 6 0 0 6 6 6 6 Sperm-tail PG-rich repeat ECR1_N PF14382.6 EST43850.1 - 8.5e-06 25.5 0.0 5.7 6.8 0.0 4.6 4 0 0 4 4 4 3 Exosome complex exonuclease RRP4 N-terminal region CYYR1 PF10873.8 EST43850.1 - 9.4 6.7 7.3 80 3.7 0.0 3.1 2 1 2 4 4 4 0 Cysteine and tyrosine-rich protein 1 EGF_Tenascin PF18720.1 EST43852.1 - 0.0018 18.2 3.2 0.0058 16.7 3.2 1.8 1 0 0 1 1 1 1 Tenascin EGF domain Ribosomal_S8 PF00410.19 EST43852.1 - 0.012 15.5 0.4 0.03 14.3 0.4 1.6 1 0 0 1 1 1 0 Ribosomal protein S8 Cas_Csy1 PF09611.10 EST43852.1 - 0.022 13.9 0.1 0.035 13.2 0.1 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy1) Laminin_EGF PF00053.24 EST43852.1 - 4.4 7.5 20.3 13 6.0 20.3 1.9 1 0 0 1 1 1 0 Laminin EGF domain VSP PF03302.13 EST43854.1 - 5.7 5.7 95.5 1.2 7.9 36.3 4.1 1 1 1 2 2 2 0 Giardia variant-specific surface protein Myb_DNA-bind_6 PF13921.6 EST43855.1 - 0.00015 21.9 0.0 0.00019 21.6 0.0 1.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EST43855.1 - 0.043 14.0 0.0 0.071 13.3 0.0 1.3 1 0 0 1 1 1 0 Myb-like DNA-binding domain CENP-B_N PF04218.13 EST43856.1 - 0.09 12.4 0.2 5.4 6.7 0.0 2.5 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain Cornichon PF03311.14 EST43859.1 - 0.67 10.3 9.8 0.13 12.6 0.6 3.4 3 0 0 3 3 3 0 Cornichon protein K-box PF01486.17 EST43860.1 - 0.33 11.2 12.1 0.049 13.8 4.9 2.3 1 1 0 2 2 2 0 K-box region Sec1 PF00995.23 EST43861.1 - 6.7e-11 42.1 2.6 0.00011 21.6 0.1 2.1 1 1 0 2 2 2 2 Sec1 family Fungal_trans_2 PF11951.8 EST43861.1 - 0.055 12.3 7.1 0.086 11.6 7.1 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain CT_C_D PF02682.16 EST43861.1 - 0.27 11.0 0.6 30 4.3 0.1 2.7 3 0 0 3 3 3 0 Carboxyltransferase domain, subdomain C and D zf-SAP30 PF13866.6 EST43861.1 - 1.9 8.7 9.2 0.12 12.5 1.2 2.5 2 0 0 2 2 2 0 SAP30 zinc-finger DegS PF05384.11 EST43862.1 - 0.014 14.9 0.5 0.028 13.9 0.5 1.5 1 0 0 1 1 1 0 Sensor protein DegS Fungal_trans_2 PF11951.8 EST43862.1 - 0.023 13.5 0.4 0.023 13.5 0.4 2.0 1 1 1 2 2 2 0 Fungal specific transcription factor domain Rop-like PF05082.13 EST43862.1 - 0.05 13.4 0.3 0.12 12.2 0.3 1.6 1 0 0 1 1 1 0 Rop-like Sec8_exocyst PF04048.14 EST43862.1 - 0.55 10.1 5.8 0.11 12.4 1.4 2.0 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain TTL PF03133.15 EST43863.1 - 1.4e-59 201.6 0.0 2.3e-59 201.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EST43863.1 - 0.0086 15.4 0.1 0.17 11.1 0.0 2.7 2 1 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EST43863.1 - 0.057 12.7 0.0 2.6 7.2 0.0 2.2 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Torus PF16131.5 EST43864.1 - 1.2e-05 26.0 0.5 1.8e-05 25.4 0.5 1.3 1 0 0 1 1 1 1 Torus domain LacAB_rpiB PF02502.18 EST43865.1 - 1e-55 187.5 0.8 1.2e-55 187.4 0.8 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase ASH PF15780.5 EST43867.1 - 3.3e-16 59.3 18.1 0.19 12.0 0.1 14.0 14 0 0 14 14 14 6 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 EST43867.1 - 0.53 10.6 18.7 2.7 8.3 0.0 7.5 8 0 0 8 8 8 0 Transmembrane protein 131-like LRR_9 PF14580.6 EST43871.1 - 1.1e-10 41.3 0.5 1.6e-10 40.8 0.5 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EST43871.1 - 3.5e-08 33.6 16.0 5.8e-06 26.5 4.4 4.1 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EST43871.1 - 0.00014 21.6 13.1 0.00058 19.6 3.7 2.9 3 1 1 4 4 4 2 Leucine rich repeat Mnd1 PF03962.15 EST43872.1 - 2.8e-14 53.1 2.4 3.8e-14 52.7 0.0 2.4 3 0 0 3 3 3 1 Mnd1 HTH domain LZ3wCH PF18517.1 EST43872.1 - 4.1e-08 33.2 0.5 1.4e-07 31.5 0.5 2.0 1 0 0 1 1 1 1 Leucine zipper with capping helix domain HALZ PF02183.18 EST43872.1 - 0.0022 18.2 4.4 0.0022 18.2 4.4 2.7 2 1 1 3 3 3 1 Homeobox associated leucine zipper RAWUL PF16207.5 EST43872.1 - 0.11 13.2 0.6 0.51 11.1 0.1 2.2 2 0 0 2 2 2 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like FtsL PF04999.13 EST43872.1 - 0.22 11.5 2.7 0.27 11.2 0.6 2.1 2 0 0 2 2 2 0 Cell division protein FtsL DUF2205 PF10224.9 EST43872.1 - 0.33 11.0 9.4 1.4 9.0 2.2 3.4 1 1 1 2 2 2 0 Short coiled-coil protein OmpH PF03938.14 EST43872.1 - 1.1 9.6 12.7 0.48 10.8 10.0 1.8 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Bap31_Bap29_C PF18035.1 EST43872.1 - 1.2 9.2 14.0 0.32 11.0 5.3 3.2 2 1 1 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain ZapB PF06005.12 EST43872.1 - 3.4 8.2 14.9 0.12 12.9 7.5 2.3 2 1 0 2 2 2 0 Cell division protein ZapB FapA PF03961.13 EST43872.1 - 3.5 6.1 13.0 10 4.6 13.0 1.8 1 1 0 1 1 1 0 Flagellar Assembly Protein A Atg29_N PF18388.1 EST43873.1 - 0.099 12.5 1.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 Atg29 N-terminal domain Myb_DNA-binding PF00249.31 EST43873.1 - 0.13 12.4 0.6 1.4 9.2 0.0 2.7 3 0 0 3 3 3 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST43873.1 - 2 8.7 6.9 7.7 6.9 0.7 3.1 3 1 0 3 3 3 0 Myb-like DNA-binding domain Thioredoxin PF00085.20 EST43874.1 - 1e-11 44.7 0.3 5.9e-09 35.8 0.4 2.2 1 1 1 2 2 2 2 Thioredoxin Thioredoxin_8 PF13905.6 EST43874.1 - 3.5e-10 40.1 0.5 4.7e-10 39.7 0.5 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 EST43874.1 - 1.3e-07 31.5 0.1 1.6e-07 31.2 0.1 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EST43874.1 - 0.00019 21.1 0.1 0.00022 20.9 0.1 1.2 1 0 0 1 1 1 1 Redoxin IF4E PF01652.18 EST43875.1 - 4.4e-10 39.6 1.0 6.5e-10 39.0 1.0 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E RNA12 PF10443.9 EST43875.1 - 0.004 15.9 3.7 0.0061 15.4 3.7 1.2 1 0 0 1 1 1 1 RNA12 protein DUF2138 PF09909.9 EST43875.1 - 0.028 12.8 0.2 0.036 12.4 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2138) IFT81_CH PF18383.1 EST43876.1 - 5.3e-10 39.6 0.2 5.3e-10 39.6 0.2 3.4 3 1 0 3 3 3 1 Intraflagellar transport 81 calponin homology domain Spore-coat_CotZ PF10612.9 EST43876.1 - 0.0065 16.6 0.9 0.021 15.0 0.9 1.9 1 0 0 1 1 1 1 Spore coat protein Z Glyco_hydro_2_C PF02836.17 EST43876.1 - 0.012 14.7 0.7 0.012 14.7 0.7 2.6 2 1 0 2 2 2 0 Glycosyl hydrolases family 2, TIM barrel domain DUF3800 PF12686.7 EST43876.1 - 0.014 16.0 0.0 5.2 7.7 0.0 3.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) Corona_NSP4_C PF16348.5 EST43876.1 - 0.085 13.7 0.1 31 5.5 0.0 2.5 2 0 0 2 2 2 0 Coronavirus nonstructural protein 4 C-terminus TPR_19 PF14559.6 EST43877.1 - 0.00025 21.5 27.0 0.0013 19.2 0.2 6.8 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 EST43877.1 - 0.0025 17.8 0.5 0.0025 17.8 0.5 9.2 12 0 0 12 12 10 2 Tetratricopeptide repeat TPR_1 PF00515.28 EST43877.1 - 0.015 15.1 0.8 0.015 15.1 0.8 7.3 9 0 0 9 9 9 0 Tetratricopeptide repeat ThiF PF00899.21 EST43877.1 - 0.02 14.2 1.1 1.8 7.9 0.1 2.5 2 0 0 2 2 2 0 ThiF family TPR_7 PF13176.6 EST43877.1 - 0.14 12.3 0.1 0.14 12.3 0.1 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 EST43877.1 - 0.46 10.7 2.7 36 4.6 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Mei5 PF10376.9 EST43877.1 - 0.54 10.1 11.7 3.7 7.4 2.1 3.3 1 1 1 2 2 2 0 Double-strand recombination repair protein YfiO PF13525.6 EST43877.1 - 0.64 9.7 7.1 0.51 10.0 1.7 3.0 2 0 0 2 2 2 0 Outer membrane lipoprotein TPR_16 PF13432.6 EST43877.1 - 1.8 9.3 8.8 39 5.0 0.0 5.2 4 2 1 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 EST43877.1 - 2.7 9.1 11.9 7.1 7.7 0.0 5.9 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 EST43877.1 - 9 6.9 9.4 10 6.8 0.0 5.3 4 1 0 4 4 4 0 Tetratricopeptide repeat LMF1 PF06762.14 EST43878.1 - 0.16 11.1 7.3 0.22 10.6 7.3 1.2 1 0 0 1 1 1 0 Lipase maturation factor DUF5582 PF17819.1 EST43881.1 - 0.028 14.9 0.1 0.051 14.0 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5582) HTH_17 PF12728.7 EST43881.1 - 0.039 14.2 0.0 0.089 13.0 0.0 1.8 1 1 0 1 1 1 0 Helix-turn-helix domain Cyt-b5 PF00173.28 EST43882.1 - 4.4e-13 49.2 0.0 4.4e-13 49.2 0.0 1.5 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain TAF6_C PF07571.13 EST43885.1 - 0.062 13.6 0.3 0.51 10.7 0.0 2.7 2 0 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain Bcl-2_3 PF15286.6 EST43885.1 - 0.15 12.8 1.0 2.8 8.6 0.1 3.0 2 0 0 2 2 2 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like zf-CHY PF05495.12 EST43886.1 - 3e-15 56.5 12.2 3e-15 56.5 12.2 4.5 1 1 1 2 2 2 1 CHY zinc finger Lipase_3 PF01764.25 EST43889.1 - 1.9e-13 50.5 0.0 3.4e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.20 EST43889.1 - 0.066 13.3 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain zf-C3HC4_3 PF13920.6 EST43890.1 - 1.2e-10 41.1 10.3 1.9e-10 40.5 10.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EST43890.1 - 3.6e-06 26.7 8.1 2.1e-05 24.3 7.9 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EST43890.1 - 4.8e-06 26.4 12.1 1e-05 25.4 12.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EST43890.1 - 3.1e-05 23.9 7.3 0.00011 22.1 7.3 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EST43890.1 - 3.1e-05 24.0 7.2 9.4e-05 22.5 7.2 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EST43890.1 - 0.00026 20.8 10.0 0.00095 19.0 10.2 1.8 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EST43890.1 - 0.0036 17.1 14.4 0.011 15.6 12.0 2.6 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EST43890.1 - 0.018 15.4 13.9 0.053 13.9 11.3 2.7 2 1 1 3 3 3 0 Ring finger domain PSI_integrin PF17205.3 EST43890.1 - 0.04 13.7 2.0 0.09 12.5 2.0 1.7 1 0 0 1 1 1 0 Integrin plexin domain DZR PF12773.7 EST43890.1 - 0.15 12.1 7.2 0.57 10.2 7.2 2.0 1 1 0 1 1 1 0 Double zinc ribbon DUF2316 PF10078.9 EST43890.1 - 0.15 12.3 4.7 1.6 9.0 0.0 2.9 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2316) zf-RING_11 PF17123.5 EST43890.1 - 0.75 9.6 13.5 6.5 6.6 0.5 2.9 2 0 0 2 2 2 0 RING-like zinc finger zf-rbx1 PF12678.7 EST43890.1 - 1.1 9.6 10.0 9.7 6.6 6.0 3.2 2 1 1 3 3 3 0 RING-H2 zinc finger domain LRR_4 PF12799.7 EST43891.1 - 8.6e-07 29.2 19.6 7.8e-05 23.0 4.1 5.2 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EST43891.1 - 0.00051 19.7 15.7 0.11 12.2 3.1 4.6 2 1 3 5 5 5 4 Leucine rich repeat LRR_1 PF00560.33 EST43891.1 - 2.3 9.1 12.4 31 5.7 0.2 5.4 4 2 0 4 4 4 0 Leucine Rich Repeat EMP24_GP25L PF01105.24 EST43893.1 - 1.6e-16 60.8 0.1 2.6e-16 60.1 0.1 1.3 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD MotA_ExbB PF01618.16 EST43893.1 - 0.058 13.1 0.0 0.058 13.1 0.0 1.6 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family DUF1427 PF07235.11 EST43893.1 - 0.15 12.0 0.1 0.15 12.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1427) UCH PF00443.29 EST43894.1 - 1.4e-32 113.2 13.0 2e-32 112.7 13.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EST43894.1 - 2.1e-17 63.2 6.4 2.1e-17 63.2 6.4 3.5 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 EST43894.1 - 8.4e-07 28.9 22.8 5.8e-06 26.1 22.8 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EST43894.1 - 0.00061 20.4 0.3 0.12 13.0 0.0 3.5 3 0 0 3 3 3 1 DUSP domain zf-UBP_var PF17807.1 EST43894.1 - 0.0051 16.5 0.2 0.0051 16.5 0.2 2.0 2 0 0 2 2 2 1 Variant UBP zinc finger AhpC-TSA PF00578.21 EST43895.1 - 4.5e-13 49.2 0.1 5.8e-13 48.8 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 EST43895.1 - 8.7e-12 45.2 0.1 1.4e-11 44.5 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 EST43895.1 - 5.7e-10 39.1 0.0 6.7e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin PF00085.20 EST43895.1 - 9.8e-10 38.4 0.1 1.6e-07 31.2 0.3 2.1 1 1 1 2 2 2 2 Thioredoxin Thioredoxin_9 PF14595.6 EST43895.1 - 5e-05 23.1 0.1 0.0036 17.1 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EST43895.1 - 0.00045 20.6 0.1 0.00069 20.0 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 EST43895.1 - 0.0073 16.1 0.3 0.0082 16.0 0.3 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein T3SS_needle_F PF09392.10 EST43895.1 - 0.19 12.0 3.8 0.31 11.3 0.9 2.4 2 1 0 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF NUDIX PF00293.28 EST43896.1 - 5.8e-09 36.1 0.0 7.8e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain LRR_8 PF13855.6 EST43897.1 - 6.3e-10 38.7 1.1 0.0032 17.2 0.1 2.8 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EST43897.1 - 0.0001 22.6 1.4 0.89 10.1 0.0 3.2 2 2 1 3 3 3 2 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 EST43897.1 - 0.0033 17.7 0.1 0.0073 16.6 0.1 1.7 1 1 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 EST43897.1 - 0.0044 17.4 1.0 10 7.1 0.1 3.8 3 0 0 3 3 3 1 Leucine Rich Repeat Fer4_20 PF14691.6 EST43898.1 - 0.02 14.7 2.5 0.061 13.1 2.5 1.8 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster DUF4164 PF13747.6 EST43898.1 - 1.8 8.9 8.2 0.72 10.2 0.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) GDE_N PF12439.8 EST43898.1 - 6.4 6.1 11.0 76 2.6 11.0 2.6 1 1 0 1 1 1 0 Glycogen debranching enzyme N terminal Myb_DNA-binding PF00249.31 EST43900.1 - 4.3e-07 30.0 1.0 7e-07 29.4 1.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST43900.1 - 2e-05 24.7 0.8 3.1e-05 24.1 0.8 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST43900.1 - 0.0012 18.7 1.1 0.0012 18.7 1.1 1.4 2 0 0 2 2 2 1 Myb DNA-binding like XPG_N PF00752.17 EST43902.1 - 8.2e-26 90.4 0.0 1.9e-25 89.3 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EST43902.1 - 3.2e-19 69.1 0.3 3.2e-19 69.1 0.3 1.9 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 EST43902.1 - 1.4e-08 35.2 0.8 7.3e-08 32.9 0.0 2.5 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.7 EST43902.1 - 0.0009 19.3 0.0 0.0021 18.1 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif XRN_N PF03159.18 EST43902.1 - 0.0015 18.0 0.0 0.0027 17.2 0.0 1.5 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus HHH_5 PF14520.6 EST43902.1 - 0.041 14.5 0.0 0.11 13.2 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain EXS PF03124.14 EST43903.1 - 9e-40 137.0 29.1 1.5e-39 136.2 29.1 1.4 1 0 0 1 1 1 1 EXS family SPX PF03105.19 EST43903.1 - 2.3e-20 73.9 5.5 4.8e-11 43.2 0.1 2.2 1 1 0 2 2 2 2 SPX domain Chalcone PF02431.15 EST43903.1 - 0.091 12.2 0.1 0.19 11.1 0.1 1.6 1 0 0 1 1 1 0 Chalcone-flavanone isomerase TB2_DP1_HVA22 PF03134.19 EST43904.1 - 9.3e-18 63.9 8.0 1.5e-17 63.3 8.0 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF4512 PF14975.6 EST43904.1 - 0.12 13.2 0.0 0.24 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) CTP_transf_1 PF01148.20 EST43905.1 - 7.7e-49 166.8 20.5 9.4e-49 166.6 20.5 1.0 1 0 0 1 1 1 1 Cytidylyltransferase family FGGY_N PF00370.21 EST43906.1 - 2.3e-61 207.5 0.8 3.3e-61 207.0 0.8 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 EST43906.1 - 4.7e-27 95.0 0.1 1.8e-26 93.1 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Proteasome PF00227.26 EST43908.1 - 6.4e-35 120.4 0.1 9.2e-35 119.9 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EST43908.1 - 1e-12 47.4 0.2 1e-12 47.4 0.2 2.3 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature LSM PF01423.22 EST43910.1 - 2.7e-10 39.8 0.9 4.8e-10 39.0 0.2 1.7 2 0 0 2 2 2 1 LSM domain Hfq PF17209.3 EST43910.1 - 3.2e-05 23.5 0.1 5.2e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Hfq protein Cas_CXXC_CXXC PF09706.10 EST43910.1 - 0.0061 16.8 1.8 0.011 16.0 1.8 1.4 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_CXXC_CXXC) Staph_haemo PF05480.11 EST43910.1 - 0.14 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Staphylococcus haemolytic protein DUF2730 PF10805.8 EST43911.1 - 0.47 10.6 3.2 1.4 9.1 0.3 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) WD40 PF00400.32 EST43912.1 - 2.5e-05 24.9 0.9 0.0001 23.0 0.1 2.5 3 0 0 3 3 3 1 WD domain, G-beta repeat Mpp10 PF04006.12 EST43913.1 - 2.9e-23 82.2 15.9 3.4e-23 82.0 15.9 1.1 1 0 0 1 1 1 1 Mpp10 protein COMP PF11598.8 EST43913.1 - 0.036 14.5 2.8 0.042 14.3 0.7 2.2 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein LRR_6 PF13516.6 EST43914.1 - 0.13 12.3 2.9 16 5.8 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich repeat PI3_PI4_kinase PF00454.27 EST43916.1 - 6.7e-20 72.0 0.4 2.2e-14 53.9 0.2 3.0 2 1 1 3 3 3 2 Phosphatidylinositol 3- and 4-kinase PP-binding_2 PF14573.6 EST43916.1 - 0.1 12.8 0.1 0.22 11.8 0.1 1.5 1 0 0 1 1 1 0 Acyl-carrier NFACT-R_1 PF05670.13 EST43918.1 - 1.5e-25 90.0 0.0 5.1e-25 88.2 0.0 2.0 1 0 0 1 1 1 1 NFACT protein RNA binding domain FbpA PF05833.11 EST43918.1 - 5.7e-18 64.9 8.1 5.7e-18 64.9 8.1 2.9 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DUF1512 PF07431.12 EST43919.1 - 0.16 10.9 4.5 0.097 11.7 2.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1512) Tmpp129 PF10272.9 EST43919.1 - 0.95 8.7 7.0 1.1 8.6 6.5 1.3 1 1 0 1 1 1 0 Putative transmembrane protein precursor DUF4897 PF16238.5 EST43919.1 - 1.2 9.0 8.2 0.29 11.0 2.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4897) Exonuc_VII_L PF02601.15 EST43919.1 - 1.5 8.3 12.2 1.8 8.0 12.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 EST43919.1 - 3.6 6.6 18.3 4.1 6.4 18.3 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 WD40 PF00400.32 EST43920.1 - 1.3e-10 41.7 0.0 0.027 15.3 0.0 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EST43920.1 - 3.9e-05 23.9 0.1 0.3 11.4 0.0 3.1 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EST43920.1 - 9.2e-05 21.9 0.1 0.00019 20.9 0.1 1.7 1 1 0 1 1 1 1 WD40-like domain Coatomer_WDAD PF04053.14 EST43920.1 - 0.00094 18.3 0.0 0.46 9.5 0.0 2.1 1 1 1 2 2 2 2 Coatomer WD associated region BBS2_Mid PF14783.6 EST43920.1 - 0.014 15.4 0.0 0.047 13.7 0.0 1.9 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region Frtz PF11768.8 EST43920.1 - 0.028 12.8 0.0 0.044 12.1 0.0 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Nbas_N PF15492.6 EST43920.1 - 0.059 12.7 0.0 10 5.3 0.0 2.2 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal HALZ PF02183.18 EST43923.1 - 0.013 15.7 0.4 0.013 15.7 0.4 5.0 5 0 0 5 5 5 0 Homeobox associated leucine zipper DUF3956 PF13104.6 EST43923.1 - 0.19 11.9 1.5 23 5.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3956) ATG16 PF08614.11 EST43923.1 - 0.68 10.1 49.9 1.8 8.7 31.5 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DNA_pol3_beta_3 PF02768.15 EST43923.1 - 0.91 9.4 10.5 0.18 11.7 0.4 3.0 2 1 1 3 3 3 0 DNA polymerase III beta subunit, C-terminal domain Rootletin PF15035.6 EST43923.1 - 3.9 7.4 42.8 0.14 12.1 4.4 3.3 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion KASH_CCD PF14662.6 EST43923.1 - 5.7 6.7 51.6 0.3 10.9 23.2 3.8 1 1 3 4 4 4 0 Coiled-coil region of CCDC155 or KASH DUF4200 PF13863.6 EST43923.1 - 7.7 6.9 39.3 1.2 9.5 10.0 4.0 2 1 0 3 3 3 0 Domain of unknown function (DUF4200) zf-RING_UBOX PF13445.6 EST43927.1 - 1.3e-11 44.3 7.9 3.2e-11 43.0 7.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EST43927.1 - 1.8e-11 44.0 9.1 4e-11 42.9 9.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EST43927.1 - 1.7e-10 40.6 9.9 3.7e-10 39.5 9.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EST43927.1 - 3.1e-10 39.8 9.5 7.3e-10 38.6 9.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EST43927.1 - 1.4e-09 37.7 10.8 2.6e-09 36.8 10.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EST43927.1 - 9.3e-09 35.5 12.0 1.8e-08 34.6 12.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EST43927.1 - 9.9e-07 28.6 10.9 2.6e-06 27.3 10.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EST43927.1 - 4.6e-06 26.4 8.3 9.1e-06 25.4 8.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EST43927.1 - 0.00013 22.2 7.4 0.0003 21.0 7.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EST43927.1 - 0.0026 17.5 6.0 0.0078 15.9 6.0 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 EST43927.1 - 0.0035 17.3 4.7 0.0068 16.4 4.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EST43927.1 - 0.024 14.4 9.9 0.14 11.9 8.5 2.3 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 EST43927.1 - 0.11 12.3 6.3 0.22 11.4 6.3 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 EST43927.1 - 0.16 12.1 9.9 0.43 10.7 9.9 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-UDP PF14569.6 EST43927.1 - 0.26 11.4 8.7 1.4 9.0 8.7 2.0 1 1 0 1 1 1 0 Zinc-binding RING-finger Beach PF02138.18 EST43928.1 - 8.3e-25 87.7 14.0 2.3e-23 83.0 5.2 3.2 3 0 0 3 3 3 2 Beige/BEACH domain Med21 PF11221.8 EST43929.1 - 0.0077 16.5 8.8 0.0092 16.2 8.3 1.3 1 1 0 1 1 1 1 Subunit 21 of Mediator complex STN1_2 PF09170.10 EST43929.1 - 0.011 15.9 1.6 0.014 15.6 1.6 1.1 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 Mg_chelatase_C PF13335.6 EST43929.1 - 0.023 15.3 0.0 0.031 14.9 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI C-terminal Exonuc_VII_L PF02601.15 EST43929.1 - 0.06 12.9 1.3 0.066 12.8 1.3 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit L31 PF09784.9 EST43929.1 - 0.085 13.3 1.8 0.16 12.4 1.7 1.6 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L31 DUF3552 PF12072.8 EST43929.1 - 0.16 11.4 5.3 0.2 11.0 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF16 PF01519.16 EST43929.1 - 2.9 8.4 9.1 18 5.9 8.8 1.9 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF5003 PF16394.5 EST43930.1 - 0.12 11.5 2.1 0.18 10.9 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5003) DUF4770 PF15994.5 EST43930.1 - 0.16 12.2 6.4 0.059 13.6 3.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) DUF3425 PF11905.8 EST43930.1 - 0.8 9.7 3.0 1.6 8.7 3.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3425) DUF3510 PF12022.8 EST43931.1 - 0.68 10.3 3.8 3 8.3 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3510) DUF4600 PF15372.6 EST43931.1 - 4.8 7.6 6.8 1.3 9.5 0.1 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4600) PTCB-BRCT PF12738.7 EST43932.1 - 0.049 13.6 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 twin BRCT domain DUF1308 PF07000.11 EST43932.1 - 0.071 13.0 0.0 0.099 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1308) Aminotran_1_2 PF00155.21 EST43933.1 - 1.1e-65 222.2 0.0 1.3e-65 222.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Baculo_p33 PF05214.12 EST43933.1 - 0.092 12.5 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Baculovirus P33 EIF4E-T PF10477.9 EST43934.1 - 0.77 8.5 3.8 0.92 8.3 3.8 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Pkinase PF00069.25 EST43935.1 - 4.5e-68 229.5 0.0 6.3e-68 229.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST43935.1 - 4.9e-32 111.2 0.0 4.4e-31 108.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EST43935.1 - 0.0027 17.1 2.3 0.51 9.6 2.8 2.9 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 EST43935.1 - 0.006 16.2 0.7 1.3 8.6 0.2 2.5 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EST43935.1 - 0.063 12.0 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase MdcG PF10620.9 EST43935.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl-dephospho-CoA transferase MdcG Prefoldin PF02996.17 EST43937.1 - 1.3e-05 25.1 0.7 2.5e-05 24.2 0.1 1.8 2 0 0 2 2 2 1 Prefoldin subunit DUF3800 PF12686.7 EST43937.1 - 0.084 13.5 0.4 0.13 12.9 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3800) Erf4 PF10256.9 EST43937.1 - 0.096 12.8 4.6 0.22 11.6 0.2 2.6 2 1 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family Mob1_phocein PF03637.17 EST43938.1 - 3e-35 121.7 3.8 3.7e-35 121.4 3.8 1.0 1 0 0 1 1 1 1 Mob1/phocein family Act-Frag_cataly PF09192.10 EST43938.1 - 0.00052 19.5 0.6 0.00052 19.5 0.6 1.5 2 0 0 2 2 2 1 Actin-fragmin kinase, catalytic AMP-binding PF00501.28 EST43940.1 - 1.1e-62 212.0 0.0 1.4e-62 211.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme HEAT PF02985.22 EST43941.1 - 0.054 13.8 0.0 40 4.8 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat BBS2_Mid PF14783.6 EST43943.1 - 0.026 14.6 0.4 0.34 11.0 0.0 2.5 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region MINDY_DUB PF04424.13 EST43944.1 - 0.088 12.8 5.5 0.28 11.2 0.1 4.1 3 0 0 3 3 3 0 MINDY deubiquitinase Coprogen_oxidas PF01218.18 EST43944.1 - 0.12 11.0 0.6 0.4 9.3 0.1 1.9 2 0 0 2 2 2 0 Coproporphyrinogen III oxidase Tape_meas_lam_C PF09718.10 EST43944.1 - 0.14 12.3 0.1 27 5.0 0.3 2.9 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) HflK_N PF12221.8 EST43947.1 - 0.019 14.9 0.1 0.051 13.6 0.1 1.7 1 0 0 1 1 1 0 Bacterial membrane protein N terminal RNase_J_C PF17770.1 EST43947.1 - 9.7 7.3 7.3 4.2 8.5 0.2 3.2 2 1 1 3 3 3 0 Ribonuclease J C-terminal domain Pkinase PF00069.25 EST43948.1 - 2e-24 86.4 5.8 5e-16 58.9 0.1 3.7 2 1 1 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 EST43948.1 - 6e-12 45.4 0.3 2.9e-08 33.3 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase PIP49_C PF12260.8 EST43948.1 - 0.0085 15.7 0.1 0.027 14.1 0.0 1.8 2 0 0 2 2 2 1 Protein-kinase domain of FAM69 Phage_holin_5_1 PF06946.11 EST43949.1 - 0.087 13.2 0.6 0.23 11.8 0.1 1.8 1 1 1 2 2 2 0 Bacteriophage A118-like holin, Hol118 YmzC PF14157.6 EST43950.1 - 0.0027 17.7 0.6 9.2 6.4 0.0 4.2 3 0 0 3 3 3 3 YmzC-like protein SHIPPO-rpt PF07004.12 EST43951.1 - 0.049 14.6 26.7 0.43 11.6 0.3 5.6 5 1 0 5 5 5 0 Sperm-tail PG-rich repeat Peptidase_M24 PF00557.24 EST43952.1 - 1.9e-48 165.0 0.0 2.5e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EST43952.1 - 1.2e-21 76.7 0.0 2.2e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Creatinase_N PF01321.18 EST43952.1 - 0.02 15.6 0.0 0.098 13.3 0.0 2.1 2 0 0 2 2 2 0 Creatinase/Prolidase N-terminal domain Kinesin PF00225.23 EST43954.1 - 8e-78 261.7 5.3 8e-78 261.7 5.3 3.1 2 1 1 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 EST43954.1 - 6.9e-18 65.0 0.1 6.9e-18 65.0 0.1 3.6 4 0 0 4 4 4 1 Microtubule binding MMR_HSR1_Xtn PF16897.5 EST43955.1 - 2.9e-36 123.7 0.1 5e-36 122.9 0.1 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EST43955.1 - 6e-20 71.4 0.0 1.4e-19 70.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 EST43955.1 - 3.1e-16 59.1 0.1 5.8e-16 58.3 0.1 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 EST43955.1 - 5.1e-11 42.3 0.0 1.1e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EST43955.1 - 0.02 14.9 4.1 0.18 11.8 0.0 2.6 2 1 1 3 3 3 0 Dynamin family MeaB PF03308.16 EST43955.1 - 0.042 12.8 0.1 0.12 11.3 0.0 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SRPRB PF09439.10 EST43955.1 - 0.079 12.4 0.5 0.15 11.5 0.0 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Ank_2 PF12796.7 EST43956.1 - 4.9e-21 75.1 0.0 6.9e-09 36.2 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EST43956.1 - 3.1e-12 45.5 0.1 0.00013 22.1 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EST43956.1 - 1.3e-10 41.3 0.0 0.00012 22.3 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EST43956.1 - 1.4e-10 41.5 0.5 0.0062 17.1 0.0 3.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EST43956.1 - 3e-07 30.6 0.0 0.02 15.3 0.0 3.2 2 2 0 2 2 2 2 Ankyrin repeat Myb_DNA-bind_7 PF15963.5 EST43959.1 - 4e-06 26.6 3.8 6.2e-06 26.0 0.1 2.5 2 1 1 3 3 3 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 EST43959.1 - 9.8e-06 25.7 0.3 0.059 13.6 0.3 2.5 2 1 0 2 2 2 2 Myb-like DNA-binding domain YtfJ_HI0045 PF09695.10 EST43959.1 - 0.0015 18.2 0.2 0.0019 17.8 0.2 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (YtfJ_HI0045) Myb_DNA-bind_5 PF13873.6 EST43959.1 - 0.035 14.2 3.0 2.1 8.5 0.6 2.6 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain DUF722 PF05263.11 EST43959.1 - 0.06 13.6 0.5 0.14 12.4 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF722) MJ1316 PF04457.12 EST43959.1 - 0.087 13.6 0.1 0.23 12.2 0.1 1.6 1 0 0 1 1 1 0 MJ1316 RNA cyclic group end recognition domain TMF_TATA_bd PF12325.8 EST43959.1 - 0.31 11.3 9.2 3.8 7.8 4.3 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding EGF_2 PF07974.13 EST43960.1 - 0.015 15.6 6.3 0.015 15.6 6.3 7.7 7 2 1 8 8 8 0 EGF-like domain DUF3149 PF11346.8 EST43960.1 - 0.043 13.4 1.3 0.11 12.1 1.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) tRNA_edit PF04073.15 EST43962.1 - 0.00067 19.7 0.0 0.0025 17.9 0.0 1.9 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain Intein_splicing PF14890.6 EST43962.1 - 0.056 13.4 0.3 2 8.4 0.1 2.2 2 0 0 2 2 2 0 Intein splicing domain CorA PF01544.18 EST43963.1 - 3.7e-05 23.2 11.2 0.00073 18.9 11.1 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Syntaxin_2 PF14523.6 EST43963.1 - 0.0028 18.0 5.0 0.0028 18.0 5.0 2.3 1 1 0 2 2 2 1 Syntaxin-like protein MetOD1 PF18546.1 EST43963.1 - 0.003 17.6 0.5 0.0076 16.2 0.5 1.7 1 0 0 1 1 1 1 Metanogen output domain 1 Prp18 PF02840.15 EST43963.1 - 0.091 12.8 0.7 6.7 6.8 0.3 2.5 2 0 0 2 2 2 0 Prp18 domain GIDA_assoc PF13932.6 EST43963.1 - 0.25 11.5 1.7 0.38 10.9 1.7 1.3 1 0 0 1 1 1 0 GidA associated domain Fib_alpha PF08702.10 EST43963.1 - 0.61 10.3 6.0 0.8 9.9 4.0 2.2 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Ank_2 PF12796.7 EST43966.1 - 1.1e-16 61.2 0.3 3.2e-07 30.8 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EST43966.1 - 2e-11 43.0 0.3 0.53 11.0 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 EST43966.1 - 3.3e-11 43.5 1.2 0.00019 21.9 0.2 3.9 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EST43966.1 - 5.6e-09 36.1 0.1 0.41 11.2 0.0 4.7 4 1 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EST43966.1 - 2.6e-06 27.6 0.0 0.028 14.8 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) MORN PF02493.20 EST43967.1 - 5.5e-10 38.6 5.7 0.069 13.1 0.1 5.9 5 1 0 5 5 5 5 MORN repeat SHIPPO-rpt PF07004.12 EST43968.1 - 0.00013 22.7 7.0 0.13 13.2 0.1 5.3 5 0 0 5 5 5 2 Sperm-tail PG-rich repeat DUF2000 PF09391.10 EST43968.1 - 0.033 14.1 0.1 0.08 12.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2000) DUF3533 PF12051.8 EST43968.1 - 5 6.0 5.7 0.96 8.3 2.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3533) Utp14 PF04615.13 EST43969.1 - 1.4e-11 43.7 35.1 5.1e-07 28.7 7.0 3.4 1 1 2 3 3 3 3 Utp14 protein DUF3368 PF11848.8 EST43969.1 - 0.19 11.5 1.5 0.62 9.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3368) Pkinase PF00069.25 EST43970.1 - 5.3e-43 147.3 0.0 6.6e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST43970.1 - 1.6e-15 57.1 0.0 1.1e-14 54.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase DHHC PF01529.20 EST43971.1 - 1.2e-30 106.4 14.6 1.2e-30 106.4 14.6 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase Claudin_2 PF13903.6 EST43971.1 - 0.0069 16.2 1.2 0.0069 16.2 1.2 2.0 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Borrelia_lipo_1 PF05714.11 EST43971.1 - 0.19 11.5 0.2 0.27 11.0 0.2 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi virulent strain associated lipoprotein DUF4231 PF14015.6 EST43971.1 - 0.46 11.0 3.7 7.5 7.1 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) ERGIC_N PF13850.6 EST43971.1 - 0.68 10.3 3.9 0.29 11.5 0.6 2.1 2 0 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF2207 PF09972.9 EST43971.1 - 8.1 5.1 8.0 5.2 5.7 2.5 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) ESCRT-II PF05871.12 EST43972.1 - 2.4e-10 40.8 2.5 2.7e-10 40.6 1.7 1.5 1 1 1 2 2 2 1 ESCRT-II complex subunit DUF4441 PF14536.6 EST43972.1 - 0.32 11.2 13.1 2.8 8.1 2.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4441) Peptidase_M16_C PF05193.21 EST43973.1 - 1.7e-07 31.4 2.1 6.4e-07 29.6 0.7 2.6 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EST43973.1 - 1.3e-05 25.2 0.0 3.9e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) DUF2387 PF09526.10 EST43974.1 - 0.4 10.9 6.9 0.5 10.6 0.1 3.5 2 1 0 3 3 3 0 Probable metal-binding protein (DUF2387) CH PF00307.31 EST43974.1 - 1.2 9.4 8.8 0.078 13.2 0.6 2.9 3 1 0 3 3 3 0 Calponin homology (CH) domain APC1_C PF18122.1 EST43974.1 - 4.1 7.3 10.4 0.35 10.8 3.1 2.6 2 2 0 2 2 2 0 Anaphase-promoting complex sub unit 1 C-terminal domain Cytochrom_NNT PF03264.14 EST43974.1 - 5.5 6.6 9.1 0.11 12.1 0.6 2.3 2 1 1 3 3 3 0 NapC/NirT cytochrome c family, N-terminal region Ax_dynein_light PF10211.9 EST43975.1 - 2e-77 259.4 11.9 2.8e-77 258.9 11.9 1.2 1 0 0 1 1 1 1 Axonemal dynein light chain Zn_protease PF05618.11 EST43975.1 - 0.018 15.0 1.2 0.061 13.2 0.9 2.1 1 1 0 1 1 1 0 Putative ATP-dependant zinc protease DUF1192 PF06698.11 EST43975.1 - 0.026 14.6 6.3 0.026 14.6 6.3 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) End3 PF12761.7 EST43975.1 - 0.069 13.3 7.4 0.035 14.3 3.3 2.1 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Lzipper-MIP1 PF14389.6 EST43975.1 - 0.082 13.2 0.1 0.082 13.2 0.1 3.2 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Snapin_Pallidin PF14712.6 EST43975.1 - 1.5 9.3 10.7 0.57 10.6 6.4 2.2 2 0 0 2 2 2 0 Snapin/Pallidin CCDC-167 PF15188.6 EST43975.1 - 1.6 9.1 9.3 4.8 7.6 9.3 1.8 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Rx_N PF18052.1 EST43975.1 - 6.8 7.0 11.6 1 9.6 3.5 2.9 2 2 1 3 3 3 0 Rx N-terminal domain W2 PF02020.18 EST43976.1 - 4e-09 36.5 3.0 4.6e-09 36.3 0.1 2.6 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Cauli_DNA-bind PF03310.13 EST43976.1 - 0.4 10.7 3.5 11 6.1 0.0 2.9 3 0 0 3 3 3 0 Caulimovirus DNA-binding protein zf-CHY PF05495.12 EST43978.1 - 1.8e-08 34.7 23.8 1.8e-08 34.7 23.8 4.5 2 1 2 4 4 4 1 CHY zinc finger zf-RING_2 PF13639.6 EST43978.1 - 2e-07 31.2 4.6 2e-07 31.2 4.6 5.8 6 1 1 7 7 7 2 Ring finger domain zinc_ribbon_6 PF14599.6 EST43978.1 - 2.7e-05 24.1 1.7 2.7e-05 24.1 1.7 5.1 4 1 1 5 5 5 2 Zinc-ribbon Sad1_UNC PF07738.13 EST43979.1 - 4.6e-07 29.9 0.0 2e-06 27.8 0.0 2.1 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal CENP-F_leu_zip PF10473.9 EST43979.1 - 0.0066 16.5 6.8 0.0066 16.5 6.8 3.1 2 1 1 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 XisI PF08869.11 EST43979.1 - 0.021 15.1 2.0 2 8.8 0.1 3.2 3 0 0 3 3 3 0 XisI protein EzrA PF06160.12 EST43979.1 - 0.42 8.7 24.1 0.17 10.0 9.0 2.7 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA Cytochrom_B562 PF07361.11 EST43979.1 - 0.7 10.6 9.8 2 9.1 3.8 2.9 1 1 1 2 2 2 0 Cytochrome b562 DUF1411 PF07199.11 EST43979.1 - 0.95 9.1 6.6 0.15 11.7 0.4 2.6 2 1 0 3 3 3 0 Protein of unknown function (DUF1411) PQQ_2 PF13360.6 EST43980.1 - 0.053 13.1 0.0 0.56 9.7 0.0 2.2 2 0 0 2 2 2 0 PQQ-like domain CENP-F_leu_zip PF10473.9 EST43981.1 - 0.037 14.1 6.8 0.046 13.7 6.8 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ZapB PF06005.12 EST43981.1 - 0.067 13.6 4.6 0.4 11.2 1.0 2.2 1 1 1 2 2 2 0 Cell division protein ZapB TSC22 PF01166.18 EST43981.1 - 0.1 12.9 6.2 0.24 11.7 2.1 2.3 1 1 1 2 2 2 0 TSC-22/dip/bun family LPP PF04728.13 EST43981.1 - 0.12 12.8 6.0 0.25 11.8 0.4 2.5 1 1 1 2 2 2 0 Lipoprotein leucine-zipper HR1 PF02185.16 EST43981.1 - 0.58 10.3 7.6 0.22 11.7 3.2 2.1 1 1 1 2 2 2 0 Hr1 repeat Aldo_ket_red PF00248.21 EST43983.1 - 1.3e-47 162.4 1.1 1.8e-47 161.9 1.1 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family YjbF PF11102.8 EST43983.1 - 0.0064 16.3 0.3 0.013 15.3 0.3 1.5 1 0 0 1 1 1 1 Group 4 capsule polysaccharide lipoprotein gfcB, YjbF Ndc80_HEC PF03801.13 EST43985.1 - 8.3e-18 64.5 0.6 8.3e-18 64.5 0.6 2.3 2 0 0 2 2 2 1 HEC/Ndc80p family COG5 PF10392.9 EST43985.1 - 0.037 14.2 0.9 0.037 14.2 0.9 4.4 3 2 1 4 4 4 0 Golgi transport complex subunit 5 Fez1 PF06818.15 EST43985.1 - 0.74 10.2 52.0 1.7 9.0 24.2 3.2 2 1 0 3 3 3 0 Fez1 Uso1_p115_C PF04871.13 EST43985.1 - 0.81 10.1 51.5 0.62 10.4 11.9 4.6 3 2 1 4 4 4 0 Uso1 / p115 like vesicle tethering protein, C terminal region GAS PF13851.6 EST43985.1 - 3.2 7.0 61.3 0.03 13.7 20.9 4.6 1 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Filament PF00038.21 EST43985.1 - 3.6 7.1 58.1 1.3 8.6 15.0 4.8 1 1 3 4 4 4 0 Intermediate filament protein DUF4140 PF13600.6 EST43985.1 - 4.3 7.8 32.7 1.9 8.9 1.1 5.6 3 2 2 5 5 5 0 N-terminal domain of unknown function (DUF4140) Roc PF08477.13 EST43986.1 - 2.2e-08 34.4 0.0 7.2e-07 29.5 0.0 2.1 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EST43986.1 - 6.1e-06 25.9 0.0 0.00088 18.9 0.0 2.1 1 1 1 2 2 2 2 Ras family Arf PF00025.21 EST43986.1 - 4.7e-05 22.9 0.0 6.3e-05 22.5 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family TniB PF05621.11 EST43986.1 - 0.0065 15.9 0.0 0.16 11.3 0.0 2.2 2 1 0 2 2 2 1 Bacterial TniB protein ANAPC4_WD40 PF12894.7 EST43987.1 - 0.011 16.0 0.2 0.19 12.0 0.0 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain TPR_16 PF13432.6 EST43988.1 - 0.0077 16.9 0.2 0.0077 16.9 0.2 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EST43988.1 - 0.035 14.3 4.4 0.18 12.0 0.6 3.0 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 AbiEi_2 PF09952.9 EST43988.1 - 0.097 12.9 0.0 0.39 10.9 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system TPR_8 PF13181.6 EST43988.1 - 0.18 12.1 0.4 0.18 12.1 0.4 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 EST43988.1 - 0.35 11.3 1.9 41 4.9 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 EST43988.1 - 0.88 10.6 7.8 18 6.5 0.0 3.8 1 1 3 4 4 4 0 Tetratricopeptide repeat ZapB PF06005.12 EST43989.1 - 0.0028 18.0 3.6 0.004 17.6 3.6 1.2 1 0 0 1 1 1 1 Cell division protein ZapB CENP-H PF05837.12 EST43989.1 - 0.0092 16.4 0.6 0.014 15.8 0.6 1.2 1 0 0 1 1 1 1 Centromere protein H (CENP-H) PRKG1_interact PF15898.5 EST43989.1 - 0.0098 16.8 0.3 0.014 16.3 0.3 1.3 1 0 0 1 1 1 1 cGMP-dependent protein kinase interacting domain YabA PF06156.13 EST43989.1 - 0.03 15.0 2.0 0.043 14.4 2.0 1.2 1 0 0 1 1 1 0 Initiation control protein YabA DASH_Dam1 PF08653.10 EST43989.1 - 0.03 14.1 0.8 0.048 13.5 0.8 1.3 1 0 0 1 1 1 0 DASH complex subunit Dam1 DUF2205 PF10224.9 EST43989.1 - 0.039 14.0 2.1 0.059 13.4 2.1 1.3 1 0 0 1 1 1 0 Short coiled-coil protein bZIP_2 PF07716.15 EST43989.1 - 0.043 13.9 3.1 0.069 13.2 3.1 1.3 1 0 0 1 1 1 0 Basic region leucine zipper Prominin PF05478.11 EST43989.1 - 0.058 11.4 0.3 0.066 11.2 0.3 1.0 1 0 0 1 1 1 0 Prominin HALZ PF02183.18 EST43989.1 - 0.11 12.7 2.5 0.16 12.2 2.5 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper DivIC PF04977.15 EST43989.1 - 0.14 11.9 1.6 0.25 11.1 1.6 1.3 1 0 0 1 1 1 0 Septum formation initiator NRBF2 PF08961.10 EST43989.1 - 0.28 10.8 4.0 0.33 10.5 4.0 1.3 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator GTP_EFTU PF00009.27 EST43991.1 - 1.6e-24 86.5 0.1 1.6e-24 86.5 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EST43991.1 - 0.00023 21.2 0.0 0.0055 16.8 0.0 3.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EST43991.1 - 0.0026 17.3 0.5 2.3 7.7 0.2 2.7 2 0 0 2 2 2 2 Ferrous iron transport protein B CDC48_N PF02359.18 EST43991.1 - 0.032 14.4 0.0 0.087 13.0 0.0 1.7 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain TraP PF07296.11 EST43991.1 - 0.072 12.3 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 TraP protein HTH_40 PF14493.6 EST43991.1 - 0.47 10.9 3.9 2.6 8.6 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain TatD_DNase PF01026.21 EST43992.1 - 4.8e-16 58.9 0.1 7.3e-16 58.3 0.1 1.3 1 1 0 1 1 1 1 TatD related DNase Asn_synthase PF00733.21 EST43993.1 - 2.3e-09 37.4 0.0 2.6e-06 27.3 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase NAD_synthase PF02540.17 EST43993.1 - 0.0064 15.6 0.0 0.015 14.4 0.0 1.7 1 0 0 1 1 1 1 NAD synthase ATP_bind_3 PF01171.20 EST43993.1 - 0.009 15.8 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 PP-loop family Elongin_A PF06881.11 EST43993.1 - 0.57 10.7 4.3 6.8 7.3 0.1 3.2 4 0 0 4 4 4 0 RNA polymerase II transcription factor SIII (Elongin) subunit A zf-C2H2_2 PF12756.7 EST43995.1 - 3.5e-25 88.3 23.1 1.2e-14 54.4 5.1 3.4 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EST43995.1 - 7.1e-09 35.8 32.0 0.11 13.4 2.2 6.2 6 0 0 6 6 6 5 C2H2-type zinc finger zf-Di19 PF05605.12 EST43995.1 - 1.9e-06 28.0 16.7 0.0026 18.0 0.4 5.1 5 0 0 5 5 5 2 Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook PF04423.14 EST43995.1 - 0.0077 16.0 11.7 0.012 15.4 1.2 3.8 4 0 0 4 4 4 1 Rad50 zinc hook motif CxC7 PF18866.1 EST43995.1 - 0.018 15.1 5.9 0.73 10.0 0.0 4.0 4 0 0 4 4 4 0 CxC7 like cysteine cluster associated with KDZ transposases Trm112p PF03966.16 EST43995.1 - 0.074 13.6 1.1 4 8.1 0.4 3.3 2 1 0 2 2 2 0 Trm112p-like protein Zn-C2H2_12 PF18112.1 EST43995.1 - 0.096 13.2 24.7 1.2 9.6 0.1 5.2 5 0 0 5 5 5 0 Autophagy receptor zinc finger-C2H2 domain DUF3449 PF11931.8 EST43995.1 - 0.11 12.3 5.7 0.28 11.0 5.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3449) zf-C2H2_12 PF18658.1 EST43995.1 - 0.11 12.1 6.5 0.36 10.4 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger C2H2-type zf-C2H2_9 PF16293.5 EST43995.1 - 0.35 10.8 10.1 1.5 8.7 0.0 4.3 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-C2H2_jaz PF12171.8 EST43995.1 - 6.6 7.1 22.8 0.31 11.4 3.1 5.1 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 EST43995.1 - 6.8 7.3 32.1 1.1 9.8 1.7 6.1 6 1 0 6 6 6 0 Zinc finger, C2H2 type FYVE PF01363.21 EST43996.1 - 4.1e-15 55.7 13.2 9.2e-15 54.5 13.2 1.6 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 EST43996.1 - 0.0083 16.3 8.7 0.0083 16.3 8.7 2.1 2 0 0 2 2 2 1 FYVE-type zinc finger CDC73_N PF16050.5 EST43996.1 - 0.32 10.3 2.6 0.86 8.9 0.6 2.4 3 0 0 3 3 3 0 Paf1 complex subunit CDC73 N-terminal SAM_1 PF00536.30 EST43998.1 - 2.7e-13 50.2 0.1 4.3e-13 49.5 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EST43998.1 - 1.1e-12 47.9 0.3 3e-12 46.5 0.1 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 EST43998.1 - 0.022 14.7 0.2 0.038 13.9 0.2 1.3 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Big_1 PF02369.16 EST43998.1 - 0.05 13.6 0.0 0.098 12.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) GDPD_2 PF13653.6 EST43998.1 - 0.062 13.8 0.9 9.4 6.8 0.4 2.3 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family TMEM70 PF06979.12 EST43999.1 - 0.22 11.9 4.6 0.15 12.5 1.6 2.3 2 0 0 2 2 2 0 Assembly, mitochondrial proton-transport ATP synth complex U6-snRNA_bdg PF10596.9 EST44000.1 - 2.5e-18 66.5 3.8 2.5e-18 66.5 3.8 3.4 3 0 0 3 3 3 1 U6-snRNA interacting domain of PrP8 PROCN PF08083.11 EST44000.1 - 9.1e-15 54.3 14.0 9.1e-15 54.3 14.0 3.9 2 1 1 4 4 4 1 PROCN (NUC071) domain U5_2-snRNA_bdg PF10597.9 EST44000.1 - 6.7e-05 23.0 0.2 6.7e-05 23.0 0.2 2.9 3 0 0 3 3 3 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 EST44000.1 - 0.2 12.0 9.9 0.46 10.9 2.6 4.0 2 0 0 2 2 2 0 RNA recognition motif of the spliceosomal PrP8 DHR10 PF18595.1 EST44001.1 - 0.23 11.5 6.9 0.088 12.9 3.8 1.8 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain FapA PF03961.13 EST44001.1 - 1.1 7.7 5.5 1.6 7.3 5.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A ERM PF00769.19 EST44003.1 - 0.0023 17.8 22.0 0.0023 17.8 22.0 1.8 2 1 0 2 2 2 1 Ezrin/radixin/moesin family V-SNARE_C PF12352.8 EST44005.1 - 0.32 11.3 2.2 9.1 6.7 0.6 2.6 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus Cnn_1N PF07989.11 EST44007.1 - 2.5e-05 24.3 2.3 2.5e-05 24.3 2.3 6.0 3 2 2 5 5 5 1 Centrosomin N-terminal motif 1 HALZ PF02183.18 EST44007.1 - 1 9.6 48.7 0.075 13.3 1.0 7.4 5 1 2 7 7 7 0 Homeobox associated leucine zipper DUF948 PF06103.11 EST44007.1 - 1.1 9.6 14.4 0.57 10.5 2.3 4.0 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4407 PF14362.6 EST44007.1 - 1.7 7.9 27.6 0.029 13.7 14.6 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) NRBF2 PF08961.10 EST44007.1 - 6.2 6.4 25.5 1.2 8.7 8.8 4.5 2 1 2 4 4 4 0 Nuclear receptor-binding factor 2, autophagy regulator KMP11 PF03037.16 EST44007.1 - 6.2 7.7 10.7 2.1 9.2 0.8 4.3 5 0 0 5 5 5 0 Kinetoplastid membrane protein 11 EF-hand_7 PF13499.6 EST44008.1 - 7.4e-14 52.0 10.4 5e-10 39.7 6.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EST44008.1 - 1.1e-11 43.7 8.9 6.4e-05 22.6 0.6 4.0 3 1 1 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 EST44008.1 - 3.6e-11 41.8 6.9 0.0012 18.2 0.5 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EST44008.1 - 7e-07 29.0 9.4 0.014 15.3 0.5 4.2 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 EST44008.1 - 0.00077 18.8 0.9 0.00077 18.8 0.9 4.0 4 0 0 4 4 4 1 EF hand Caleosin PF05042.13 EST44008.1 - 0.0026 17.7 2.8 0.37 10.7 0.2 2.3 1 1 1 2 2 2 2 Caleosin related protein SPARC_Ca_bdg PF10591.9 EST44008.1 - 0.011 16.1 5.3 0.041 14.2 3.0 2.4 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Polysacc_syn_2C PF08485.10 EST44008.1 - 0.031 13.9 2.8 1.4 8.7 0.0 3.2 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein C-terminal DUF3887 PF13026.6 EST44008.1 - 0.036 14.9 6.2 0.29 12.0 0.7 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3887) EF-hand_10 PF14788.6 EST44008.1 - 0.039 13.8 2.2 0.039 13.8 2.2 2.8 1 1 2 3 3 3 0 EF hand DUF2789 PF10982.8 EST44008.1 - 0.089 13.0 0.4 0.089 13.0 0.4 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF2789) DUF2689 PF10894.8 EST44009.1 - 0.047 13.5 0.8 0.14 12.0 0.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2689) Cyclin_N PF00134.23 EST44010.1 - 0.00086 19.1 0.2 0.0011 18.7 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain UQ_con PF00179.26 EST44011.1 - 7.3e-34 116.4 0.7 8.2e-34 116.3 0.7 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 EST44011.1 - 0.00043 20.1 0.4 0.00056 19.8 0.4 1.4 1 1 0 1 1 1 1 UEV domain Dus PF01207.17 EST44014.1 - 1.3e-27 96.7 0.0 1.6e-27 96.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) EAL PF00563.20 EST44014.1 - 0.019 14.5 0.1 0.097 12.2 0.0 2.0 1 1 0 2 2 2 0 EAL domain DNA_pol3_a_NII PF11490.8 EST44014.1 - 0.037 13.9 0.4 0.078 12.9 0.4 1.6 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II SlyX PF04102.12 EST44015.1 - 0.0016 19.0 2.5 0.0018 18.8 2.5 1.2 1 0 0 1 1 1 1 SlyX ADIP PF11559.8 EST44015.1 - 0.014 15.5 1.5 0.017 15.2 1.5 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding UPF0242 PF06785.11 EST44015.1 - 0.026 14.6 1.2 0.029 14.5 1.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF2779 PF11074.8 EST44015.1 - 0.051 14.1 0.1 0.058 13.9 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function(DUF2779) Baculo_p24 PF05073.12 EST44015.1 - 0.071 12.9 0.5 0.071 12.9 0.5 1.0 1 0 0 1 1 1 0 Baculovirus P24 capsid protein Fe-ADH PF00465.19 EST44017.1 - 7.8e-96 321.0 0.0 1.2e-95 320.4 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Aldedh PF00171.22 EST44017.1 - 1.1e-26 93.4 0.7 1e-21 77.0 0.4 2.1 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Fe-ADH_2 PF13685.6 EST44017.1 - 2.1e-14 53.8 0.1 7.5e-06 25.8 0.0 2.4 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase UQ_con PF00179.26 EST44019.1 - 5.7e-25 87.6 1.3 1e-24 86.8 1.3 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EST44019.1 - 0.00045 20.5 0.3 0.0012 19.1 0.3 1.8 1 0 0 1 1 1 1 RWD domain UQ_con PF00179.26 EST44020.1 - 3.1e-34 117.6 0.1 3.5e-34 117.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EST44020.1 - 0.0003 21.0 0.1 0.00039 20.7 0.1 1.2 1 0 0 1 1 1 1 RWD domain UFC1 PF08694.11 EST44020.1 - 0.0018 17.9 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 L6_membrane PF05805.12 EST44020.1 - 0.0067 16.0 0.0 0.0084 15.7 0.0 1.1 1 0 0 1 1 1 1 L6 membrane protein RAP PF08373.10 EST44021.1 - 0.16 12.1 2.1 6.8 6.9 0.0 2.6 2 1 0 2 2 2 0 RAP domain SlyX PF04102.12 EST44023.1 - 0.0016 19.0 2.5 0.0018 18.8 2.5 1.2 1 0 0 1 1 1 1 SlyX ADIP PF11559.8 EST44023.1 - 0.014 15.5 1.5 0.017 15.2 1.5 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding UPF0242 PF06785.11 EST44023.1 - 0.026 14.6 1.2 0.029 14.5 1.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF2779 PF11074.8 EST44023.1 - 0.051 14.1 0.1 0.058 13.9 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function(DUF2779) Baculo_p24 PF05073.12 EST44023.1 - 0.071 12.9 0.5 0.071 12.9 0.5 1.0 1 0 0 1 1 1 0 Baculovirus P24 capsid protein zf-RING_UBOX PF13445.6 EST44024.1 - 1.8e-06 27.9 7.6 1.8e-06 27.9 7.6 3.1 3 1 1 4 4 4 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EST44024.1 - 7e-05 22.6 12.8 7e-05 22.6 12.8 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EST44024.1 - 0.00087 19.4 14.5 0.00087 19.4 14.5 3.4 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EST44024.1 - 0.0044 16.9 11.9 0.0044 16.9 11.9 3.7 3 1 1 4 4 4 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EST44024.1 - 0.026 14.4 12.4 0.026 14.4 12.4 3.7 3 1 1 4 4 4 0 Prokaryotic RING finger family 4 ArfGap PF01412.18 EST44025.1 - 1.7e-26 92.6 1.0 1.7e-26 92.6 1.0 1.6 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf WAK_assoc PF14380.6 EST44026.1 - 0.17 12.7 2.9 3.5 8.4 2.7 2.9 2 0 0 2 2 2 0 Wall-associated receptor kinase C-terminal End3 PF12761.7 EST44028.1 - 0.2 11.8 19.3 0.14 12.3 17.7 1.5 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 PriA_3primeBD PF17764.1 EST44028.1 - 0.2 11.6 2.0 9 6.3 0.0 2.5 1 1 1 2 2 2 0 3′ DNA-binding domain (3′BD) XLF PF09302.11 EST44028.1 - 1 9.5 17.3 0.32 11.1 3.7 3.0 2 1 0 3 3 3 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component DUF4407 PF14362.6 EST44028.1 - 1.4 8.2 9.7 1.8 7.8 9.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 EST44028.1 - 1.6 8.3 12.4 2 7.9 12.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit MutS_III PF05192.18 EST44028.1 - 3.4 7.9 10.0 4.4 7.5 10.0 1.1 1 0 0 1 1 1 0 MutS domain III MSA-2c PF12238.8 EST44028.1 - 3.8 7.5 10.5 6.3 6.7 10.5 1.5 1 0 0 1 1 1 0 Merozoite surface antigen 2c RseA_C PF03873.13 EST44028.1 - 6.5 7.1 10.1 12 6.3 0.2 3.1 2 1 1 3 3 3 0 Anti sigma-E protein RseA, C-terminal domain Mt_ATP-synt_D PF05873.12 EST44028.1 - 9.2 6.1 20.6 0.081 12.8 1.2 3.1 1 1 2 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) H-kinase_dim PF02895.14 EST44028.1 - 9.5 6.7 11.0 68 4.0 7.9 2.6 1 1 1 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Rhodanese PF00581.20 EST44029.1 - 4.9e-05 23.8 0.0 0.00033 21.1 0.0 2.2 2 0 0 2 2 2 1 Rhodanese-like domain PI3K_1B_p101 PF10486.9 EST44029.1 - 0.0039 15.1 2.2 0.0046 14.8 2.2 1.1 1 0 0 1 1 1 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Gemini_AL3 PF01407.17 EST44031.1 - 0.027 14.3 1.1 0.067 13.0 0.1 2.1 3 0 0 3 3 3 0 Geminivirus AL3 protein T4SS PF07996.11 EST44032.1 - 0.0025 18.2 3.0 0.0025 18.2 3.0 2.8 1 1 2 3 3 3 1 Type IV secretion system proteins FlxA PF14282.6 EST44032.1 - 4.2 7.4 20.7 0.87 9.6 6.0 2.6 2 0 0 2 2 2 0 FlxA-like protein DUF5320 PF17253.2 EST44032.1 - 8.6 7.5 9.5 0.41 11.8 1.4 2.8 3 1 0 3 3 3 0 Family of unknown function (DUF5320) SHIPPO-rpt PF07004.12 EST44033.1 - 8.1e-07 29.7 10.3 2.5 9.2 0.0 5.6 5 0 0 5 5 5 4 Sperm-tail PG-rich repeat Flavodoxin_1 PF00258.25 EST44034.1 - 0.00011 22.4 0.0 0.00023 21.4 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 EST44034.1 - 0.026 14.7 0.0 0.081 13.2 0.0 1.8 2 0 0 2 2 2 0 Flavodoxin domain UPF0261 PF06792.11 EST44034.1 - 0.1 11.5 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) TRL PF13146.6 EST44034.1 - 0.13 12.5 0.4 0.37 11.1 0.1 1.9 2 0 0 2 2 2 0 TRL-like protein family DOCK-C2 PF14429.6 EST44035.1 - 6.5e-18 65.3 1.1 6.5e-18 65.3 1.1 3.4 4 0 0 4 4 4 1 C2 domain in Dock180 and Zizimin proteins DUF2990 PF11693.8 EST44035.1 - 0.12 12.6 0.8 31 4.8 0.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2990) DEAD PF00270.29 EST44037.1 - 5.6e-31 107.6 1.4 1.5e-30 106.3 1.4 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EST44037.1 - 2.1e-19 69.9 0.0 2.2e-18 66.6 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EST44037.1 - 2.7e-10 40.3 0.1 6.4e-10 39.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EST44037.1 - 3.3e-08 33.7 0.0 7.5e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit NOG1_N PF17835.1 EST44037.1 - 0.0037 17.2 0.1 0.009 16.0 0.1 1.6 1 0 0 1 1 1 1 NOG1 N-terminal helical domain DUF1772 PF08592.11 EST44039.1 - 0.12 12.7 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) Ank_2 PF12796.7 EST44040.1 - 1.8e-20 73.3 2.6 3.5e-12 46.7 0.5 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EST44040.1 - 7.8e-11 42.3 2.8 0.0028 18.2 0.1 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EST44040.1 - 3.3e-10 39.3 0.0 0.33 11.6 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 EST44040.1 - 1.4e-09 38.0 0.5 0.0037 17.6 0.1 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EST44040.1 - 3.4e-08 33.6 0.1 0.23 12.0 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat L_lac_phage_MSP PF06488.11 EST44040.1 - 0.0093 15.3 0.2 0.016 14.5 0.2 1.3 1 0 0 1 1 1 1 Phage tail tube protein DUF3463 PF11946.8 EST44040.1 - 0.067 13.0 2.4 0.62 9.9 1.0 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF3463) DUF755 PF05501.11 EST44040.1 - 0.25 11.6 7.6 0.48 10.7 7.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Urb2 PF10441.9 EST44041.1 - 0.68 9.8 13.3 1.8 8.5 0.0 3.8 3 1 0 3 3 3 0 Urb2/Npa2 family Tfb2 PF03849.14 EST44043.1 - 4.9e-08 32.3 3.5 0.0014 17.7 0.2 2.4 2 0 0 2 2 2 2 Transcription factor Tfb2 DASH_Dam1 PF08653.10 EST44044.1 - 0.55 10.1 3.5 1.1 9.1 1.4 2.4 2 0 0 2 2 2 0 DASH complex subunit Dam1 Unstab_antitox PF09720.10 EST44047.1 - 0.051 13.6 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Putative addiction module component E2F_TDP PF02319.20 EST44047.1 - 0.19 11.8 1.6 0.59 10.2 0.0 2.6 3 0 0 3 3 3 0 E2F/DP family winged-helix DNA-binding domain Tryp_alpha_amyl PF00234.22 EST44048.1 - 0.054 13.9 0.0 0.06 13.8 0.0 1.1 1 0 0 1 1 1 0 Protease inhibitor/seed storage/LTP family DUF4015 PF13200.6 EST44053.1 - 0.034 13.2 1.1 0.046 12.8 1.1 1.1 1 0 0 1 1 1 0 Putative glycosyl hydrolase domain IMS PF00817.20 EST44056.1 - 4.3e-15 56.0 0.1 1.1e-14 54.7 0.1 1.7 1 0 0 1 1 1 1 impB/mucB/samB family BRCT_2 PF16589.5 EST44056.1 - 7.6e-08 32.7 0.2 3.7e-07 30.4 0.0 2.3 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EST44056.1 - 2.2e-06 28.0 0.0 1.3e-05 25.5 0.0 2.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 EST44056.1 - 0.067 13.5 0.0 0.24 11.7 0.0 2.0 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain CPW_WPC PF09717.10 EST44056.1 - 0.24 12.4 0.9 6 7.9 0.1 2.7 2 0 0 2 2 2 0 Plasmodium falciparum domain of unknown function (CPW_WPC) DUF4556 PF15094.6 EST44058.1 - 0.00075 18.8 0.1 0.0015 17.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4556) eIF3_p135 PF12807.7 EST44058.1 - 0.04 14.0 0.6 0.061 13.4 0.6 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 TetR_C_8 PF14278.6 EST44058.1 - 0.057 13.5 7.2 1.5 9.0 0.5 2.6 2 1 0 2 2 2 0 Transcriptional regulator C-terminal region Glycogen_syn PF05693.13 EST44059.1 - 2.2e-126 423.0 0.6 3e-126 422.5 0.6 1.1 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 EST44059.1 - 9.6e-07 28.5 0.0 0.00069 19.2 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 EST44059.1 - 0.00014 21.6 0.4 0.00068 19.4 0.4 2.0 1 1 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.6 EST44059.1 - 0.00063 20.2 0.0 0.13 12.6 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Enolase_C PF00113.22 EST44059.1 - 0.13 11.5 0.1 0.23 10.7 0.1 1.4 1 0 0 1 1 1 0 Enolase, C-terminal TIM barrel domain Chal_sti_synt_N PF00195.19 EST44060.1 - 0.38 10.1 2.9 0.4 10.1 0.0 2.4 3 1 1 4 4 4 0 Chalcone and stilbene synthases, N-terminal domain EAP30 PF04157.16 EST44061.1 - 0.00083 18.7 1.6 0.0013 18.1 1.6 1.3 1 0 0 1 1 1 1 EAP30/Vps36 family G6PD_N PF00479.22 EST44061.1 - 0.0064 17.1 4.0 0.44 11.2 0.2 2.1 1 1 1 2 2 2 2 Glucose-6-phosphate dehydrogenase, NAD binding domain Laminin_II PF06009.12 EST44061.1 - 0.013 15.5 8.9 0.35 10.9 7.6 2.1 1 1 1 2 2 2 0 Laminin Domain II Tropomyosin_1 PF12718.7 EST44061.1 - 0.024 14.8 9.9 0.041 14.0 9.6 1.6 1 1 0 1 1 1 0 Tropomyosin like KIP1 PF07765.12 EST44061.1 - 0.025 14.7 7.5 0.46 10.6 0.2 3.3 1 1 2 3 3 3 0 KIP1-like protein Lsr2 PF11774.8 EST44061.1 - 0.067 13.3 2.6 0.078 13.1 1.0 1.8 1 1 1 2 2 2 0 Lsr2 V_ATPase_I PF01496.19 EST44061.1 - 0.13 10.1 7.4 0.14 10.0 7.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SecA_DEAD PF07517.14 EST44061.1 - 0.96 8.7 6.5 17 4.6 6.5 2.0 1 1 0 1 1 1 0 SecA DEAD-like domain Csm1_N PF18504.1 EST44061.1 - 1.7 9.0 12.2 3.7 7.9 0.7 3.0 1 1 2 3 3 3 0 Csm1 N-terminal domain Rho_Binding PF08912.11 EST44061.1 - 3.3 8.6 11.8 13 6.7 7.4 2.5 2 0 0 2 2 2 0 Rho Binding Fib_alpha PF08702.10 EST44061.1 - 4 7.6 12.9 5.9 7.1 12.3 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family FlxA PF14282.6 EST44061.1 - 5.8 7.0 20.7 43 4.2 20.7 2.3 1 1 0 1 1 1 0 FlxA-like protein APG6_N PF17675.1 EST44061.1 - 6.3 7.3 14.8 15 6.1 6.0 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region UPF0242 PF06785.11 EST44061.1 - 7.5 6.6 19.8 13 5.8 19.8 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Peptidase_C50 PF03568.17 EST44062.1 - 3.4e-09 36.3 0.0 3.4e-09 36.3 0.0 3.2 3 0 0 3 3 3 1 Peptidase family C50 DUF5109 PF17134.4 EST44062.1 - 3 7.8 8.1 0.68 9.9 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5109) ANAPC4_WD40 PF12894.7 EST44063.1 - 0.0065 16.8 0.0 1.5 9.2 0.0 2.8 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain KAP PF05804.12 EST44064.1 - 1.5e-44 152.3 25.9 2.8e-44 151.4 8.7 3.3 3 0 0 3 3 3 3 Kinesin-associated protein (KAP) Arm PF00514.23 EST44064.1 - 0.0052 16.8 0.0 1.7 8.8 0.0 3.7 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Rad10 PF03834.14 EST44064.1 - 0.048 13.7 1.8 1.1 9.3 0.0 2.9 2 0 0 2 2 2 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) MEKHLA PF08670.11 EST44064.1 - 0.066 13.1 1.6 0.19 11.6 1.6 1.8 1 0 0 1 1 1 0 MEKHLA domain ABC_cobalt PF09819.9 EST44064.1 - 0.07 13.3 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 ABC-type cobalt transport system, permease component DUF4888 PF16229.5 EST44064.1 - 3.8 7.5 10.1 1.7 8.6 0.7 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4888) TFIIS_C PF01096.18 EST44065.1 - 1.7e-16 59.7 9.9 1.7e-16 59.7 9.9 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EST44065.1 - 3.7e-07 29.9 0.3 3.7e-07 29.9 0.3 3.0 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Auto_anti-p27 PF06677.12 EST44065.1 - 0.01 16.0 12.1 0.05 13.8 1.4 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zinc_ribbon_2 PF13240.6 EST44065.1 - 0.13 12.0 0.2 0.13 12.0 0.2 3.4 2 1 0 2 2 2 0 zinc-ribbon domain zf-Mss51 PF13824.6 EST44065.1 - 0.18 11.9 0.3 0.18 11.9 0.3 2.9 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Baculo_LEF5_C PF11792.8 EST44065.1 - 0.29 10.8 4.0 0.55 10.0 4.0 1.5 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain PhnA_Zn_Ribbon PF08274.12 EST44065.1 - 1.9 8.5 14.6 2.7 8.0 4.4 3.2 3 0 0 3 3 3 0 PhnA Zinc-Ribbon DUF1610 PF07754.11 EST44065.1 - 2 8.4 12.2 2.5 8.2 3.6 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1610) Zn_Tnp_IS1595 PF12760.7 EST44065.1 - 5.5 7.0 16.5 4.8 7.2 4.9 2.7 2 2 0 2 2 2 0 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.6 EST44065.1 - 7.4 6.1 12.7 5.9 6.4 1.8 3.8 3 1 1 4 4 4 0 zinc-ribbon domain Fer4 PF00037.27 EST44066.1 - 3.4e-08 32.9 18.2 3.1e-06 26.8 5.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 EST44066.1 - 8.5e-06 25.8 15.8 2.5e-05 24.4 16.2 1.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 EST44066.1 - 1.5e-05 25.5 15.5 6e-05 23.6 16.0 1.7 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 EST44066.1 - 2.6e-05 24.4 15.2 7.2e-05 23.0 1.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 EST44066.1 - 3.3e-05 23.8 4.1 3.3e-05 23.8 4.1 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_2 PF12797.7 EST44066.1 - 9.3e-05 22.3 14.3 0.00046 20.1 2.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 EST44066.1 - 0.00014 21.9 13.7 0.00018 21.5 13.7 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EST44066.1 - 0.00039 21.3 11.4 0.0033 18.3 1.6 2.1 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 EST44066.1 - 0.00039 20.5 16.4 0.0027 17.8 2.1 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_11 PF13247.6 EST44066.1 - 0.00075 19.6 7.6 0.0008 19.5 7.6 1.0 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_3 PF12798.7 EST44066.1 - 0.0065 17.3 23.5 0.021 15.7 7.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.6 EST44066.1 - 0.19 12.0 13.1 0.36 11.0 13.1 1.5 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 EST44066.1 - 2.6 8.6 17.6 4.8e+02 1.3 17.8 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 EST44066.1 - 2.7 8.6 17.7 1.6e+03 -0.3 17.8 2.1 1 1 0 1 1 1 0 4Fe-4S dicluster domain RNA_capsid PF03035.14 EST44067.1 - 7.6 6.5 10.2 20 5.1 10.2 1.7 1 0 0 1 1 1 0 Calicivirus putative RNA polymerase/capsid protein Ribosomal_S24e PF01282.19 EST44068.1 - 1.9e-19 69.4 0.5 1.9e-19 69.4 0.5 1.6 2 0 0 2 2 2 1 Ribosomal protein S24e Thioredoxin_2 PF13098.6 EST44068.1 - 0.037 14.5 0.1 0.043 14.3 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain zf-UBR PF02207.20 EST44069.1 - 7.2e-13 48.5 16.1 7.2e-13 48.5 16.1 3.7 3 1 1 4 4 4 1 Putative zinc finger in N-recognin (UBR box) zf-RING_UBOX PF13445.6 EST44069.1 - 1.9e-05 24.6 0.3 1.9e-05 24.6 0.3 3.9 3 1 1 4 4 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EST44069.1 - 0.00015 21.5 1.3 0.00015 21.5 1.3 4.0 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EST44069.1 - 0.00017 21.4 4.9 0.00017 21.4 4.9 4.1 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EST44069.1 - 0.00029 21.1 5.4 0.00029 21.1 5.4 4.3 3 2 0 3 3 2 1 Ring finger domain zf-RING_5 PF14634.6 EST44069.1 - 0.0011 18.9 4.4 0.0011 18.9 4.4 3.9 3 0 0 3 3 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 EST44069.1 - 0.0072 16.6 6.2 0.0072 16.6 6.2 3.8 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-Nse PF11789.8 EST44069.1 - 0.1 12.4 3.5 0.47 10.3 3.5 2.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF1125 PF06563.11 EST44069.1 - 1.4 8.9 7.5 10 6.1 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1125) zf-RING_11 PF17123.5 EST44069.1 - 1.8 8.4 18.7 0.039 13.7 0.7 4.0 3 0 0 3 3 3 0 RING-like zinc finger zf-C3H2C3 PF17122.5 EST44069.1 - 2.2 8.4 15.4 0.44 10.6 0.6 3.7 3 0 0 3 3 3 0 Zinc-finger HypA PF01155.19 EST44069.1 - 4.2 7.4 16.6 0.56 10.2 1.4 3.7 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DMPK_coil PF08826.10 EST44070.1 - 0.3 11.2 0.2 0.3 11.2 0.2 2.1 2 0 0 2 2 2 0 DMPK coiled coil domain like MscL PF01741.18 EST44070.1 - 1 9.7 7.0 2.3 8.5 0.2 2.8 3 0 0 3 3 3 0 Large-conductance mechanosensitive channel, MscL Helicase_C PF00271.31 EST44071.1 - 7.9e-27 93.8 0.4 7.9e-27 93.8 0.4 2.7 1 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EST44071.1 - 2.2e-22 79.7 1.1 4.4e-22 78.7 1.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EST44071.1 - 0.00055 19.7 0.1 0.00055 19.7 0.1 2.1 1 1 1 2 2 2 1 SWI2/SNF2 ATPase AAA_19 PF13245.6 EST44071.1 - 0.00086 19.7 0.2 0.003 17.9 0.1 1.9 2 1 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 EST44071.1 - 0.0026 17.7 0.2 0.0095 15.8 0.0 2.0 2 0 0 2 2 2 1 Helicase AAA PF00004.29 EST44071.1 - 0.0028 18.1 0.7 0.013 15.9 0.7 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.21 EST44071.1 - 0.01 15.4 6.6 0.026 14.1 6.7 1.5 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain WhiA_N PF10298.9 EST44071.1 - 0.012 15.6 1.1 0.032 14.3 0.3 2.1 2 0 0 2 2 2 0 WhiA N-terminal LAGLIDADG-like domain AAA_30 PF13604.6 EST44071.1 - 0.022 14.5 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EST44071.1 - 0.033 14.5 1.5 0.48 10.7 1.5 2.4 1 1 0 1 1 1 0 AAA domain NeuB PF03102.14 EST44071.1 - 0.04 13.4 0.1 0.06 12.8 0.1 1.3 1 0 0 1 1 1 0 NeuB family PhoH PF02562.16 EST44071.1 - 0.05 13.0 1.8 0.75 9.2 0.1 2.7 3 0 0 3 3 3 0 PhoH-like protein Flavi_DEAD PF07652.14 EST44071.1 - 0.13 12.2 0.0 0.36 10.8 0.0 1.8 1 1 0 1 1 1 0 Flavivirus DEAD domain AAA_11 PF13086.6 EST44071.1 - 1.2 8.8 5.2 7.7 6.2 5.2 2.4 1 1 0 1 1 1 0 AAA domain Adaptin_binding PF10199.9 EST44072.1 - 0.00063 20.3 0.3 0.0009 19.8 0.3 1.3 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Myb_DNA-binding PF00249.31 EST44073.1 - 7.6e-06 26.0 0.1 1.4e-05 25.2 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain UCH PF00443.29 EST44074.1 - 3.4e-18 66.1 17.1 3.4e-18 66.1 17.1 2.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UPF0086 PF01868.16 EST44075.1 - 1.7e-08 34.2 0.0 4.4e-08 32.9 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function UPF0086 DUF3181 PF11378.8 EST44075.1 - 0.14 12.5 0.2 0.23 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3181) PP2C PF00481.21 EST44077.1 - 3.1e-39 135.1 0.0 2.5e-29 102.7 0.0 2.6 2 1 0 2 2 2 2 Protein phosphatase 2C LRR_6 PF13516.6 EST44077.1 - 6.1e-05 22.7 2.0 0.26 11.4 0.0 4.3 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.7 EST44077.1 - 0.0022 18.3 1.2 13 6.3 0.0 4.1 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) DUF4200 PF13863.6 EST44078.1 - 6e-14 52.5 23.9 6e-14 52.5 23.9 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4200) Coatomer_g_Cpla PF16381.5 EST44079.1 - 0.024 14.7 2.3 0.18 12.0 0.0 3.3 4 1 0 4 4 4 0 Coatomer subunit gamma-1 C-terminal appendage platform RUN PF02759.19 EST44080.1 - 0.59 10.1 9.4 4.4 7.2 0.4 4.0 2 0 0 2 2 2 0 RUN domain DUF1947 PF09183.10 EST44082.1 - 0.066 13.5 0.4 0.066 13.5 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) 2CSK_N PF08521.10 EST44082.1 - 0.17 12.0 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Two-component sensor kinase N-terminal ZapB PF06005.12 EST44083.1 - 0.82 10.2 17.1 6.6 7.3 4.0 3.1 2 0 0 2 2 2 0 Cell division protein ZapB CENP-H PF05837.12 EST44083.1 - 2.5 8.5 11.5 0.7 10.3 3.3 2.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) I_LWEQ PF01608.17 EST44083.1 - 9.8 6.4 13.5 35 4.6 8.0 2.4 1 1 1 2 2 2 0 I/LWEQ domain Fe_hyd_lg_C PF02906.14 EST44084.1 - 1.4e-37 129.7 0.1 1.8e-37 129.3 0.1 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fer4 PF00037.27 EST44084.1 - 5.3e-13 48.2 8.0 6.2e-08 32.1 1.7 2.8 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 EST44084.1 - 1.1e-07 31.9 12.3 1.1e-07 31.9 12.3 2.7 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 EST44084.1 - 1.6e-07 31.8 20.9 2e-07 31.5 11.9 3.3 3 1 1 4 4 4 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 EST44084.1 - 9.2e-07 28.7 11.9 6.1e-05 22.9 3.9 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 EST44084.1 - 4.3e-06 26.7 24.7 0.00041 20.4 14.9 3.0 3 1 1 4 4 3 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 EST44084.1 - 5.3e-05 23.3 28.8 0.00095 19.3 16.6 3.1 3 1 1 4 4 3 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 EST44084.1 - 6.3e-05 23.2 13.7 0.00095 19.5 1.9 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 EST44084.1 - 8.3e-05 23.0 12.1 8.3e-05 23.0 12.1 2.7 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EST44084.1 - 0.00018 22.4 0.5 0.00018 22.4 0.5 3.7 4 0 0 4 4 4 2 4Fe-4S double cluster binding domain Fer4_8 PF13183.6 EST44084.1 - 0.0009 19.6 10.1 0.0009 19.6 10.1 2.5 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 EST44084.1 - 0.0013 18.7 11.0 0.0041 17.1 2.7 3.6 4 0 0 4 4 3 2 4Fe-4S binding domain Fer4_18 PF13746.6 EST44084.1 - 0.0088 16.2 2.0 0.0088 16.2 2.0 2.9 2 1 1 3 3 3 2 4Fe-4S dicluster domain ETF_QO PF05187.13 EST44084.1 - 0.017 15.3 11.5 0.053 13.7 2.4 2.9 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_13 PF13370.6 EST44084.1 - 0.028 14.9 12.4 0.77 10.4 3.1 2.7 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 EST44084.1 - 0.74 10.6 11.6 6.5 7.6 3.3 2.9 2 1 1 3 3 3 0 4Fe-4S single cluster domain Myb_DNA-binding PF00249.31 EST44085.1 - 1.4e-21 76.4 2.1 1.1e-12 47.9 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST44085.1 - 3.8e-16 59.1 0.9 2.1e-11 43.9 0.5 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EST44085.1 - 2.3e-08 34.1 0.0 0.00023 21.1 0.0 2.4 1 1 1 2 2 2 2 SLIDE TPR_2 PF07719.17 EST44086.1 - 8.8e-16 56.7 2.7 0.024 14.7 0.0 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 EST44086.1 - 8.7e-15 53.8 0.6 0.00049 19.8 0.0 7.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 EST44086.1 - 8.5e-11 42.0 2.6 0.0056 16.9 0.1 5.8 3 1 2 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 EST44086.1 - 9.6e-10 37.9 2.1 0.19 12.0 0.0 7.1 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 EST44086.1 - 1.4e-09 38.3 3.4 1.3e-06 28.8 0.1 4.4 4 1 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EST44086.1 - 1.1e-08 35.1 3.5 0.17 12.1 0.0 4.4 3 2 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EST44086.1 - 6.4e-08 32.6 1.3 0.003 17.7 0.1 4.7 1 1 4 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 EST44086.1 - 6.9e-06 26.5 4.4 0.21 12.5 0.1 5.6 4 2 3 7 7 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 EST44086.1 - 1e-05 25.1 0.4 0.18 11.5 0.0 4.6 3 1 1 4 4 4 1 TPR repeat TPR_16 PF13432.6 EST44086.1 - 1.4e-05 25.6 1.5 0.0021 18.7 0.0 3.8 4 1 1 5 5 4 2 Tetratricopeptide repeat Tcf25 PF04910.14 EST44086.1 - 0.00027 20.1 0.1 0.00055 19.1 0.1 1.4 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_17 PF13431.6 EST44086.1 - 0.00049 20.3 1.0 1.9 9.1 0.0 4.8 5 1 0 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EST44086.1 - 0.0015 18.4 2.1 0.45 10.7 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 EST44086.1 - 0.0018 18.8 4.7 10 7.0 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EST44086.1 - 0.0057 16.7 0.7 0.96 9.5 0.1 3.1 2 1 1 3 3 3 1 Putative TPR-like repeat TPR_20 PF14561.6 EST44086.1 - 0.012 15.9 0.1 8.4 6.8 0.0 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EST44086.1 - 0.019 14.8 0.2 0.9 9.5 0.0 3.5 6 0 0 6 6 3 0 Tetratricopeptide repeat ChAPs PF09295.10 EST44086.1 - 0.12 11.3 0.5 4 6.3 0.2 2.5 1 1 2 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF3856 PF12968.7 EST44086.1 - 0.16 12.0 0.7 5.2 7.1 0.0 2.9 3 0 0 3 3 3 0 Domain of Unknown Function (DUF3856) DUF809 PF05663.11 EST44086.1 - 0.25 11.5 1.6 0.44 10.7 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF809) Ribosomal_S5 PF00333.20 EST44087.1 - 4e-27 94.0 3.3 6.5e-27 93.3 3.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 EST44087.1 - 1e-21 76.2 0.0 1.9e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain HSP70 PF00012.20 EST44089.1 - 0.003 15.8 0.2 0.003 15.8 0.2 2.2 2 0 0 2 2 2 1 Hsp70 protein Ribosomal_S4Pg PF11993.8 EST44089.1 - 0.026 14.6 4.9 0.069 13.2 4.9 1.7 1 0 0 1 1 1 0 Ribosomal S4P (gammaproteobacterial) MutL PF13941.6 EST44089.1 - 0.053 12.1 0.1 0.096 11.3 0.1 1.3 1 0 0 1 1 1 0 MutL protein NUP214 PF16755.5 EST44091.1 - 0.25 10.6 0.0 0.32 10.2 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 MarR_2 PF12802.7 EST44093.1 - 0.00034 20.5 0.0 0.2 11.6 0.0 2.6 2 0 0 2 2 2 2 MarR family MarR PF01047.22 EST44093.1 - 0.016 15.1 0.0 0.05 13.5 0.0 1.8 1 0 0 1 1 1 0 MarR family Fe_dep_repress PF01325.19 EST44093.1 - 0.018 15.2 0.0 0.054 13.7 0.0 1.8 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain TFIIE_alpha PF02002.17 EST44093.1 - 0.026 14.4 0.0 0.11 12.4 0.0 2.0 2 1 0 2 2 2 0 TFIIE alpha subunit WWE PF02825.20 EST44093.1 - 0.69 10.6 2.3 2.7 8.7 0.3 2.6 2 0 0 2 2 2 0 WWE domain PDZ_5 PF17817.1 EST44094.1 - 0.22 11.8 0.3 0.92 9.8 0.0 2.2 2 0 0 2 2 2 0 PDZ domain Cu2_monooxygen PF01082.20 EST44095.1 - 0.066 13.4 0.0 0.09 13.0 0.0 1.3 1 0 0 1 1 1 0 Copper type II ascorbate-dependent monooxygenase, N-terminal domain SID-1_RNA_chan PF13965.6 EST44096.1 - 3.3 6.0 4.6 4.2 5.7 4.6 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 WD40 PF00400.32 EST44097.1 - 0.00027 21.6 4.2 4.6 8.3 0.1 4.6 4 1 0 4 4 4 2 WD domain, G-beta repeat eIF2A PF08662.11 EST44097.1 - 0.00055 19.9 0.4 0.076 12.9 0.2 2.7 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 EST44097.1 - 0.0084 16.4 0.0 10 6.5 0.0 3.2 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain OST-HTH PF12872.7 EST44098.1 - 0.049 13.5 0.1 0.32 10.8 0.1 2.5 1 1 0 1 1 1 0 OST-HTH/LOTUS domain Adeno_E3_15_3 PF03307.14 EST44098.1 - 7 6.6 11.2 0.057 13.4 0.7 3.0 3 0 0 3 3 3 0 Adenovirus 15.3kD protein in E3 region DUF948 PF06103.11 EST44101.1 - 1.3 9.3 10.1 0.58 10.5 1.7 2.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Frtz PF11768.8 EST44102.1 - 6.4e-05 21.5 1.7 0.00046 18.6 0.1 2.9 4 0 0 4 4 4 1 WD repeat-containing and planar cell polarity effector protein Fritz WD40 PF00400.32 EST44102.1 - 0.00013 22.7 0.2 0.08 13.8 0.0 4.4 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF1730 PF08331.10 EST44102.1 - 0.11 12.4 0.1 0.31 11.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1730) BNIP3 PF06553.12 EST44103.1 - 0.095 12.4 0.2 0.15 11.7 0.2 1.2 1 0 0 1 1 1 0 BNIP3 ATP_synth_reg PF14960.6 EST44103.1 - 0.22 11.0 0.2 0.22 11.0 0.2 2.3 2 0 0 2 2 2 0 ATP synthase regulation DUF3810 PF12725.7 EST44103.1 - 2.4 7.4 10.6 1.1 8.5 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) CMS1 PF14617.6 EST44104.1 - 1.3e-16 60.7 0.1 1.3e-16 60.7 0.1 1.5 2 1 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Baculo_LEF-3 PF05847.11 EST44104.1 - 0.011 14.9 0.6 0.013 14.7 0.6 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus late expression factor 3 (LEF-3) Thioredoxin_9 PF14595.6 EST44104.1 - 0.079 12.7 0.1 0.079 12.7 0.1 2.9 3 1 1 4 4 4 0 Thioredoxin EGF_2 PF07974.13 EST44110.1 - 0.0031 17.8 12.8 0.0031 17.8 12.8 19.6 21 1 0 21 21 21 7 EGF-like domain Sulfatase PF00884.23 EST44111.1 - 3.6e-11 43.0 1.7 4.8e-11 42.6 1.7 1.2 1 0 0 1 1 1 1 Sulfatase Sensor PF13796.6 EST44111.1 - 0.03 14.4 0.1 0.06 13.4 0.1 1.4 1 0 0 1 1 1 0 Putative sensor Phosphodiest PF01663.22 EST44111.1 - 0.39 10.3 2.4 5.1 6.6 2.4 2.2 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4690 PF15756.5 EST44113.1 - 0.57 10.8 2.3 0.74 10.5 2.3 1.1 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Adaptin_N PF01602.20 EST44114.1 - 3.8e-40 137.9 17.1 5.1e-40 137.5 17.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region zf-C2H2_jaz PF12171.8 EST44118.1 - 0.076 13.3 0.6 0.076 13.3 0.6 3.9 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Aminotran_4 PF01063.19 EST44119.1 - 1.9e-22 80.2 0.1 4.3e-22 79.1 0.1 1.5 1 1 0 1 1 1 1 Amino-transferase class IV DUF3719 PF12516.8 EST44119.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3719) zf-UBR PF02207.20 EST44120.1 - 5.6e-11 42.5 10.7 5.6e-11 42.5 10.7 3.2 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) zinc_ribbon_15 PF17032.5 EST44120.1 - 0.071 13.9 0.6 0.071 13.9 0.6 4.6 4 0 0 4 4 4 0 zinc-ribbon family zf-B_box PF00643.24 EST44120.1 - 2.3 8.4 16.6 6.9 6.9 0.7 3.6 2 1 0 2 2 2 0 B-box zinc finger Cupin_2 PF07883.11 EST44121.1 - 0.13 12.0 0.4 0.21 11.4 0.4 1.3 1 0 0 1 1 1 0 Cupin domain zf-CHCC PF10276.9 EST44122.1 - 0.37 10.9 4.3 11 6.1 0.1 3.4 4 1 1 5 5 5 0 Zinc-finger domain zf-ribbon_3 PF13248.6 EST44122.1 - 2 7.9 10.0 0.35 10.3 3.8 2.6 2 1 0 2 2 2 0 zinc-ribbon domain Fox-1_C PF12414.8 EST44123.1 - 0.051 14.0 0.2 0.053 13.9 0.2 1.1 1 0 0 1 1 1 0 Calcitonin gene-related peptide regulator C terminal Pox_A11 PF05061.13 EST44123.1 - 0.21 10.9 0.0 0.23 10.7 0.0 1.0 1 0 0 1 1 1 0 Poxvirus A11 Protein Myb_DNA-bind_7 PF15963.5 EST44124.1 - 0.0047 16.8 1.0 0.0066 16.3 1.0 1.2 1 0 0 1 1 1 1 Myb DNA-binding like Podoplanin PF05808.11 EST44125.1 - 0.087 12.9 3.9 0.21 11.7 4.1 1.6 1 1 0 1 1 1 0 Podoplanin DUF4366 PF14283.6 EST44125.1 - 1.7 8.7 6.0 5.4 7.0 6.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) VSP PF03302.13 EST44126.1 - 1.4e-07 30.8 79.5 0.00023 20.1 18.8 3.3 2 1 1 3 3 3 3 Giardia variant-specific surface protein Podoplanin PF05808.11 EST44126.1 - 0.0059 16.7 0.8 0.016 15.4 0.8 1.6 1 0 0 1 1 1 1 Podoplanin Furin-like_2 PF15913.5 EST44126.1 - 0.0076 16.4 9.8 0.0076 16.4 9.8 6.2 2 2 4 6 6 6 4 Furin-like repeat, cysteine-rich DUF3042 PF11240.8 EST44126.1 - 0.078 13.0 0.8 0.21 11.6 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) Insulin_TMD PF17870.1 EST44126.1 - 0.11 12.6 0.1 0.3 11.2 0.1 1.7 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF4366 PF14283.6 EST44126.1 - 0.17 11.9 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF2613 PF11021.8 EST44126.1 - 0.2 11.8 3.5 5.3 7.2 4.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) VSP PF03302.13 EST44129.1 - 4e-13 49.0 73.1 1.4e-06 27.5 24.4 3.0 1 1 2 3 3 3 3 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST44129.1 - 0.59 10.3 64.6 1.9 8.7 3.9 4.6 1 1 4 5 5 5 0 Furin-like repeat, cysteine-rich zinc_ribbon_4 PF13717.6 EST44129.1 - 1.5 8.8 0.0 1.5 8.8 0.0 9.7 10 3 0 10 10 10 0 zinc-ribbon domain CAAD PF14159.6 EST44130.1 - 2.4 8.0 5.5 7 6.6 0.1 3.2 2 1 1 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase SHIPPO-rpt PF07004.12 EST44131.1 - 6.3e-10 39.5 31.2 0.028 15.3 0.0 8.9 9 0 0 9 9 9 7 Sperm-tail PG-rich repeat Glutaredoxin PF00462.24 EST44132.1 - 0.2 11.9 1.4 0.78 10.0 0.2 2.3 2 0 0 2 2 2 0 Glutaredoxin AAA_21 PF13304.6 EST44133.1 - 0.0011 18.9 3.1 0.0015 18.4 3.1 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system OpgC_C PF10129.9 EST44134.1 - 0.0022 16.9 0.5 0.02 13.8 0.5 2.0 1 1 0 1 1 1 1 OpgC protein DUF1624 PF07786.12 EST44134.1 - 0.017 14.7 0.9 0.026 14.1 0.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1624) SHIPPO-rpt PF07004.12 EST44135.1 - 9.8e-06 26.3 1.3 1.3 10.1 0.0 3.6 3 0 0 3 3 3 3 Sperm-tail PG-rich repeat DUF2046 PF09755.9 EST44136.1 - 0.0017 17.7 2.4 0.0021 17.3 2.4 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) HAUS5 PF14817.6 EST44136.1 - 0.03 13.1 1.2 0.041 12.6 1.2 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Fzo_mitofusin PF04799.13 EST44136.1 - 0.095 12.3 0.9 0.12 11.9 0.9 1.2 1 0 0 1 1 1 0 fzo-like conserved region Myb_DNA-bind_7 PF15963.5 EST44140.1 - 0.00012 21.8 0.2 0.00012 21.8 0.2 1.2 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 EST44140.1 - 0.0024 18.1 0.0 0.0038 17.5 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EST44140.1 - 0.0078 16.4 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EST44140.1 - 0.059 13.6 0.3 0.13 12.5 0.3 1.6 1 1 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 EST44142.1 - 0.00012 21.8 0.2 0.00012 21.8 0.2 1.2 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 EST44142.1 - 0.0024 18.1 0.0 0.0038 17.5 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EST44142.1 - 0.0078 16.4 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EST44142.1 - 0.059 13.6 0.3 0.13 12.5 0.3 1.6 1 1 0 1 1 1 0 SANT/Myb-like domain of DAMP1 zf-DBF PF07535.12 EST44143.1 - 0.14 12.3 0.1 0.46 10.6 0.1 1.9 1 0 0 1 1 1 0 DBF zinc finger Pentapeptide_4 PF13599.6 EST44145.1 - 0.0068 16.5 0.9 6.5 7.0 0.1 3.0 2 0 0 2 2 2 2 Pentapeptide repeats (9 copies) AlaDh_PNT_C PF01262.21 EST44145.1 - 0.024 14.0 1.6 0.04 13.2 0.2 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DUF3784 PF12650.7 EST44146.1 - 4 7.7 10.8 0.33 11.2 2.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DUF3877 PF12993.7 EST44148.1 - 5.4 6.8 11.2 1.6 8.5 0.4 3.6 2 2 2 4 4 4 0 Domain of unknown function, E. rectale Gene description (DUF3877) Nse4-Nse3_bdg PF15412.6 EST44150.1 - 0.096 12.8 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Binding domain of Nse4/EID3 to Nse3-MAGE CdiI_N PF18228.1 EST44151.1 - 0.13 12.1 2.2 2.2 8.2 1.5 2.5 3 0 0 3 3 3 0 CdiI N-terminal domain Myb_DNA-binding PF00249.31 EST44153.1 - 0.00034 20.7 0.0 0.0005 20.2 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST44153.1 - 0.018 15.3 0.2 0.03 14.6 0.2 1.6 1 1 0 1 1 1 0 Myb-like DNA-binding domain KxDL PF10241.9 EST44154.1 - 0.059 13.7 6.2 0.054 13.8 3.6 2.1 1 1 0 2 2 2 0 Uncharacterized conserved protein FlaC_arch PF05377.11 EST44154.1 - 0.087 13.2 2.1 4.4 7.8 0.4 2.7 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Sigma70_r4_2 PF08281.12 EST44155.1 - 0.03 14.0 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Myb_DNA-bind_7 PF15963.5 EST44157.1 - 0.00021 21.1 0.6 0.00022 21.1 0.6 1.1 1 0 0 1 1 1 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EST44157.1 - 0.0023 18.1 0.6 0.0031 17.7 0.6 1.2 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-binding PF00249.31 EST44157.1 - 0.033 14.4 0.0 0.04 14.1 0.0 1.2 1 0 0 1 1 1 0 Myb-like DNA-binding domain Acetyltransf_11 PF13720.6 EST44157.1 - 0.075 13.5 0.0 0.16 12.4 0.0 1.5 1 1 1 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 ANAPC4_WD40 PF12894.7 EST44158.1 - 1.7e-09 37.9 0.0 0.7 10.2 0.0 5.3 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EST44158.1 - 6.5e-06 26.8 3.9 0.74 10.8 0.0 5.8 7 0 0 7 7 7 2 WD domain, G-beta repeat zf-CHY PF05495.12 EST44160.1 - 2.5e-05 24.7 25.0 2.5e-05 24.7 25.0 3.4 2 1 0 2 2 2 1 CHY zinc finger Prok-RING_4 PF14447.6 EST44160.1 - 0.013 15.4 7.1 0.013 15.4 7.1 4.3 4 2 0 4 4 4 0 Prokaryotic RING finger family 4 PX PF00787.24 EST44161.1 - 1.1e-10 41.5 0.0 2e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 PX domain Jnk-SapK_ap_N PF09744.9 EST44161.1 - 0.0052 17.0 0.9 0.0086 16.3 0.9 1.2 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Vps54_N PF10475.9 EST44161.1 - 0.014 14.7 0.8 0.022 14.1 0.8 1.2 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex Laminin_II PF06009.12 EST44161.1 - 0.26 11.3 2.3 0.35 10.9 1.5 1.6 2 0 0 2 2 2 0 Laminin Domain II ABC2_membrane PF01061.24 EST44162.1 - 9e-24 84.1 36.2 9e-24 84.1 36.2 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 EST44162.1 - 4.6e-23 82.2 0.0 9.3e-23 81.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 EST44162.1 - 0.0031 17.4 0.0 0.0055 16.6 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EST44162.1 - 0.0058 17.0 0.1 0.014 15.8 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 EST44162.1 - 0.013 15.9 0.0 0.05 14.0 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EST44162.1 - 0.015 15.8 0.0 0.021 15.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 EST44162.1 - 0.023 14.1 0.0 0.85 9.0 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ATPase_2 PF01637.18 EST44162.1 - 0.063 13.2 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 EST44162.1 - 0.071 12.9 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EST44162.1 - 0.082 13.0 0.2 0.16 12.1 0.2 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 EST44162.1 - 0.16 12.3 0.0 1.1 9.5 0.1 2.2 2 0 0 2 2 2 0 AAA domain Choline_transpo PF04515.12 EST44165.1 - 2.6e-48 164.9 42.9 2.6e-48 164.9 42.9 2.5 2 1 0 2 2 2 1 Plasma-membrane choline transporter UPF0242 PF06785.11 EST44165.1 - 5.8 7.0 9.3 8.4 6.4 1.7 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF485 PF04341.12 EST44168.1 - 0.085 12.8 0.2 0.085 12.8 0.2 3.7 2 1 1 3 3 3 0 Protein of unknown function, DUF485 EGF PF00008.27 EST44170.1 - 0.019 15.2 8.7 0.019 15.2 8.7 9.1 7 1 1 8 8 8 0 EGF-like domain EGF_2 PF07974.13 EST44170.1 - 0.019 15.3 11.7 0.019 15.3 11.7 7.3 5 1 1 6 6 6 0 EGF-like domain Pectate_lyase_3 PF12708.7 EST44170.1 - 0.21 11.4 4.1 0.084 12.7 0.9 1.9 2 0 0 2 2 2 0 Pectate lyase superfamily protein Apolipoprotein PF01442.18 EST44173.1 - 0.0085 16.0 2.8 0.02 14.7 2.8 1.7 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Lebercilin PF15619.6 EST44173.1 - 5.5 6.6 9.5 1.5 8.4 5.9 1.9 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Pkinase PF00069.25 EST44174.1 - 1.5e-12 47.5 0.0 2.2e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EST44174.1 - 9.3e-10 38.8 0.5 4.6e-05 23.5 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EST44174.1 - 0.00016 21.1 0.0 0.00027 20.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 EST44174.1 - 0.028 13.7 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Choline_kinase PF01633.20 EST44174.1 - 0.048 13.3 0.0 0.099 12.2 0.0 1.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase RIO1 PF01163.22 EST44174.1 - 0.068 12.8 0.0 0.083 12.5 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 EST44174.1 - 0.078 12.0 0.1 0.11 11.5 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Ost5 PF05251.12 EST44176.1 - 0.016 15.5 1.3 0.017 15.4 1.3 1.2 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit 5 NADH_dh_m_C1 PF15088.6 EST44176.1 - 0.046 13.3 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial LSM PF01423.22 EST44177.1 - 4.9e-09 35.7 0.0 6.1e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain Cas_csx3 PF09620.10 EST44179.1 - 0.3 11.0 1.2 0.76 9.7 0.1 2.1 3 0 0 3 3 3 0 CRISPR-associated protein (Cas_csx3) PhoLip_ATPase_C PF16212.5 EST44180.1 - 5.9e-40 137.6 22.9 5.9e-40 137.6 22.9 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal E1-E2_ATPase PF00122.20 EST44180.1 - 6.7e-16 58.3 0.7 5.3e-15 55.4 0.0 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EST44180.1 - 8.2e-13 49.1 0.0 3e-07 30.9 0.0 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase PhoLip_ATPase_N PF16209.5 EST44180.1 - 2.2e-10 40.0 2.3 1.1e-09 37.8 2.3 2.3 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EST44180.1 - 4.7e-10 39.4 0.1 1.6e-07 31.3 0.0 2.5 2 0 0 2 2 2 2 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EST44180.1 - 0.0025 17.6 0.1 0.022 14.5 0.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase zf-CHY PF05495.12 EST44182.1 - 5.8e-09 36.3 24.3 5.8e-09 36.3 24.3 4.0 3 1 1 4 4 4 1 CHY zinc finger rRNA_proc-arch PF13234.6 EST44182.1 - 0.031 14.2 0.0 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 rRNA-processing arch domain rRNA_processing PF08524.11 EST44191.1 - 0.0037 17.3 4.2 0.0051 16.9 4.2 1.2 1 0 0 1 1 1 1 rRNA processing Myb_DNA-binding PF00249.31 EST44193.1 - 7e-07 29.3 0.6 1.3e-06 28.5 0.6 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST44193.1 - 2.8e-06 27.5 1.0 5.3e-06 26.6 1.0 1.6 1 1 0 1 1 1 1 Myb-like DNA-binding domain UIM PF02809.20 EST44195.1 - 2.6 8.2 6.9 0.36 10.8 0.7 2.9 3 0 0 3 3 3 0 Ubiquitin interaction motif Kinesin PF00225.23 EST44196.1 - 1.2e-45 155.9 7.2 2.3e-43 148.4 7.2 2.6 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EST44196.1 - 2.6e-08 33.9 0.1 2.6e-08 33.9 0.1 2.3 2 2 0 2 2 2 1 Microtubule binding AAA_16 PF13191.6 EST44196.1 - 0.02 15.3 0.0 0.05 14.0 0.0 1.7 2 1 0 2 2 2 0 AAA ATPase domain RB_B PF01857.20 EST44196.1 - 0.043 13.9 1.6 0.084 12.9 1.6 1.6 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain AAA_24 PF13479.6 EST44196.1 - 0.063 13.0 0.2 0.22 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EST44196.1 - 0.071 12.5 0.0 0.18 11.2 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Lys-AminoMut_A PF09043.11 EST44198.1 - 0.019 13.4 0.1 0.047 12.2 0.1 1.6 2 0 0 2 2 2 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit KAR PF15222.6 EST44198.1 - 0.075 13.3 2.1 0.35 11.2 0.0 2.8 2 1 1 3 3 3 0 Kidney androgen-regulated EOS1 PF12326.8 EST44199.1 - 0.77 9.7 4.1 1.9 8.4 1.2 2.4 2 0 0 2 2 2 0 N-glycosylation protein Plk4_PB2 PF18409.1 EST44199.1 - 8.4 7.1 10.2 5.5 7.7 0.1 4.3 5 1 1 6 6 6 0 Polo-like Kinase 4 Polo Box 2 PGM_PMM_IV PF00408.20 EST44200.1 - 1e-06 28.8 0.0 1.4e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain EGF PF00008.27 EST44201.1 - 0.0014 18.9 7.7 0.0014 18.9 7.7 14.2 13 2 0 13 13 13 6 EGF-like domain EGF_2 PF07974.13 EST44201.1 - 0.0034 17.7 35.2 0.0079 16.6 14.6 15.3 15 4 3 18 18 18 8 EGF-like domain Phage_holin_3_6 PF07332.11 EST44201.1 - 0.11 12.6 0.3 0.17 12.0 0.3 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Bacteriocin_IIc PF10439.9 EST44201.1 - 0.19 11.8 2.2 0.39 10.9 2.2 1.5 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Syndecan PF01034.20 EST44201.1 - 0.23 11.4 0.6 0.42 10.5 0.6 1.3 1 0 0 1 1 1 0 Syndecan domain DUF4690 PF15756.5 EST44201.1 - 0.33 11.6 1.2 0.83 10.3 1.2 1.6 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Radial_spoke PF04712.12 EST44202.1 - 1.2 8.0 18.1 59 2.4 18.7 2.2 1 1 1 2 2 2 0 Radial spokehead-like protein DUF740 PF05340.12 EST44202.1 - 9.4 4.8 7.5 12 4.5 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) DUF3896 PF13035.6 EST44204.1 - 0.0089 16.2 1.1 1.3 9.2 0.2 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3896) PH_9 PF15410.6 EST44204.1 - 0.032 14.6 0.4 0.039 14.3 0.4 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain Pkinase PF00069.25 EST44205.1 - 3.2e-61 207.0 0.0 3.7e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST44205.1 - 6.6e-39 133.7 0.0 8.4e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EST44205.1 - 0.00079 18.5 0.2 0.0011 18.0 0.2 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EST44205.1 - 0.0033 16.8 0.1 0.057 12.7 0.0 2.2 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EST44205.1 - 0.0072 15.1 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 EST44205.1 - 0.025 14.2 1.5 0.054 13.1 0.9 1.7 1 1 1 2 2 2 0 Choline/ethanolamine kinase RIO1 PF01163.22 EST44205.1 - 0.042 13.5 0.4 0.17 11.5 0.1 1.8 1 1 1 2 2 2 0 RIO1 family APH PF01636.23 EST44205.1 - 0.052 13.5 0.0 1.2 9.0 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family MRP-L20 PF12824.7 EST44206.1 - 0.018 15.2 1.6 0.037 14.2 1.6 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 LIN37 PF15306.6 EST44206.1 - 4.6 7.4 8.0 0.17 12.1 1.6 1.8 2 0 0 2 2 2 0 LIN37 Myb_DNA-binding PF00249.31 EST44208.1 - 1.8e-05 24.8 0.1 3.1e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST44208.1 - 0.0016 18.3 0.2 0.0018 18.1 0.2 1.1 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 EST44208.1 - 0.0023 18.1 0.4 0.0032 17.7 0.4 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Phage_lysozyme2 PF18013.1 EST44208.1 - 0.024 14.7 0.2 0.027 14.5 0.2 1.1 1 0 0 1 1 1 0 Phage tail lysozyme Laminin_EGF PF00053.24 EST44211.1 - 0.006 16.7 41.8 0.54 10.4 20.7 3.0 1 1 1 2 2 2 2 Laminin EGF domain EGF_2 PF07974.13 EST44211.1 - 0.035 14.5 17.8 0.035 14.5 17.8 4.2 3 2 1 4 4 4 0 EGF-like domain GBP_PSP PF02425.15 EST44211.1 - 0.68 9.6 0.2 0.68 9.6 0.2 4.8 4 1 0 5 5 5 0 Paralytic/GBP/PSP peptide Laminin_EGF PF00053.24 EST44212.1 - 0.0039 17.3 37.4 0.39 10.9 9.4 3.8 2 1 1 3 3 3 3 Laminin EGF domain Protocadherin PF08374.11 EST44213.1 - 0.036 14.1 0.2 0.062 13.3 0.2 1.3 1 0 0 1 1 1 0 Protocadherin TMEM154 PF15102.6 EST44213.1 - 0.08 12.8 0.2 0.15 12.0 0.2 1.3 1 0 0 1 1 1 0 TMEM154 protein family Podoplanin PF05808.11 EST44213.1 - 0.31 11.2 1.4 0.57 10.3 1.4 1.4 1 0 0 1 1 1 0 Podoplanin DUF2970 PF11174.8 EST44213.1 - 0.45 10.4 8.2 0.77 9.7 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) Histone PF00125.24 EST44215.1 - 8.5e-12 45.6 1.0 4e-11 43.4 0.1 1.9 1 1 1 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EST44215.1 - 2.8e-08 33.9 0.1 5e-08 33.1 0.0 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-18kDa PF02269.16 EST44215.1 - 0.025 14.6 0.9 0.038 14.0 0.9 1.5 1 1 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Histone_H2A_C PF16211.5 EST44215.1 - 0.19 11.5 0.0 0.19 11.5 0.0 2.4 3 0 0 3 3 3 0 C-terminus of histone H2A HSBP1 PF06825.12 EST44216.1 - 0.19 11.6 3.1 0.48 10.3 0.1 2.8 3 0 0 3 3 3 0 Heat shock factor binding protein 1 DUF2613 PF11021.8 EST44217.1 - 0.06 13.5 2.0 0.11 12.6 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) HSBP1 PF06825.12 EST44220.1 - 0.19 11.6 3.1 0.48 10.3 0.1 2.8 3 0 0 3 3 3 0 Heat shock factor binding protein 1 Histone PF00125.24 EST44221.1 - 8.5e-12 45.6 1.0 4e-11 43.4 0.1 1.9 1 1 1 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EST44221.1 - 2.8e-08 33.9 0.1 5e-08 33.1 0.0 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-18kDa PF02269.16 EST44221.1 - 0.025 14.6 0.9 0.038 14.0 0.9 1.5 1 1 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Histone_H2A_C PF16211.5 EST44221.1 - 0.19 11.5 0.0 0.19 11.5 0.0 2.4 3 0 0 3 3 3 0 C-terminus of histone H2A Glyco_hydro_20 PF00728.22 EST44223.1 - 1.2e-22 80.8 5.1 1.3e-17 64.3 2.2 2.8 1 1 1 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain DUF3742 PF12553.8 EST44224.1 - 0.085 13.0 0.2 0.14 12.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) Syndecan PF01034.20 EST44224.1 - 0.48 10.4 1.9 0.96 9.4 1.9 1.5 1 0 0 1 1 1 0 Syndecan domain ARA70 PF12489.8 EST44225.1 - 0.038 14.2 1.0 0.038 14.2 1.0 1.9 1 1 1 2 2 2 0 Nuclear coactivator DMP12 PF16779.5 EST44225.1 - 0.062 13.3 2.2 0.091 12.8 2.2 1.3 1 0 0 1 1 1 0 DNA-mimic protein Pkinase PF00069.25 EST44226.1 - 1.5e-27 96.6 0.0 4.4e-27 95.1 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST44226.1 - 1.6e-05 24.4 0.0 4.3e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EST44226.1 - 0.0047 16.9 0.2 0.16 11.9 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Phage_fiber_C PF06820.12 EST44229.1 - 0.19 12.1 1.4 0.51 10.7 0.3 2.0 1 1 1 2 2 2 0 Putative prophage tail fibre C-terminus VSP PF03302.13 EST44230.1 - 8.1e-09 34.8 259.0 0.0053 15.7 40.4 9.5 1 1 7 8 8 8 6 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST44230.1 - 0.00012 22.2 12.7 0.00012 22.2 12.7 11.4 1 1 10 11 11 11 3 Furin-like repeat, cysteine-rich CNP_C_terminal PF17839.1 EST44231.1 - 2 9.2 5.9 0.41 11.4 1.6 2.0 2 0 0 2 2 2 0 C-terminal domain of cyclic nucleotide phosphodiesterase VSP PF03302.13 EST44232.1 - 0.57 9.0 85.3 1.5 7.6 51.3 3.2 1 1 2 3 3 3 0 Giardia variant-specific surface protein Insulin_TMD PF17870.1 EST44232.1 - 1.5 8.9 5.8 2.8 8.1 5.8 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Phage_coat PF09063.10 EST44233.1 - 0.016 15.2 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 Phage PP7 coat protein Glycoprot_B_PH2 PF17417.2 EST44234.1 - 0.11 12.9 4.6 4.6 7.6 0.2 3.0 1 1 1 2 2 2 0 Herpesvirus Glycoprotein B PH-like domain COPIIcoated_ERV PF07970.12 EST44234.1 - 0.74 9.6 5.0 0.19 11.5 1.2 1.9 2 0 0 2 2 2 0 Endoplasmic reticulum vesicle transporter Prismane PF03063.20 EST44235.1 - 1.2e-96 324.4 0.0 1.7e-96 324.0 0.0 1.1 1 0 0 1 1 1 1 Prismane/CO dehydrogenase family Glyco_hydro_35 PF01301.19 EST44236.1 - 3.4e-35 122.2 0.1 5.2e-35 121.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 EST44236.1 - 0.052 14.1 0.4 0.88 10.2 0.2 2.5 2 0 0 2 2 2 0 Beta-galactosidase jelly roll domain HMD PF03201.16 EST44236.1 - 0.14 12.4 0.1 4.6 7.5 0.0 2.5 2 0 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase POR_N PF01855.19 EST44237.1 - 1.7e-61 207.9 0.2 4.9e-61 206.4 0.1 1.8 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 EST44237.1 - 1.2e-19 71.0 0.0 2.4e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase EKR PF10371.9 EST44237.1 - 3e-15 55.8 0.2 2e-14 53.1 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function PFOR_II PF17147.4 EST44237.1 - 1e-12 48.3 0.0 6.3e-12 45.7 0.0 2.3 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II Fer4_7 PF12838.7 EST44237.1 - 4.8e-10 39.9 7.7 4.8e-10 39.9 7.7 2.4 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EST44237.1 - 3.7e-09 37.4 18.8 1.1e-08 35.9 6.6 2.8 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 EST44237.1 - 5.5e-08 32.9 6.4 5.5e-08 32.9 6.4 3.0 3 0 0 3 3 2 1 4Fe-4S dicluster domain TPP_enzyme_C PF02775.21 EST44237.1 - 1.5e-07 31.4 0.0 4.2e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4 PF00037.27 EST44237.1 - 1.8e-07 30.7 23.0 4.4e-05 23.1 4.1 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_8 PF13183.6 EST44237.1 - 1.9e-06 28.2 5.2 1.9e-06 28.2 5.2 2.2 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 EST44237.1 - 4e-06 26.7 22.8 0.00018 21.4 4.0 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_10 PF13237.6 EST44237.1 - 4.4e-06 26.7 14.2 9.1e-06 25.7 10.8 2.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 EST44237.1 - 1.4e-05 24.9 21.8 0.0033 17.4 4.5 3.6 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_21 PF14697.6 EST44237.1 - 3.6e-05 23.8 15.1 0.0013 18.8 15.1 3.0 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 EST44237.1 - 7.5e-05 23.2 6.8 7.5e-05 23.2 6.8 2.5 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_4 PF12800.7 EST44237.1 - 0.0027 18.1 1.8 0.0027 18.1 1.8 3.8 4 0 0 4 4 3 2 4Fe-4S binding domain Fer4_18 PF13746.6 EST44237.1 - 0.062 13.5 16.6 0.046 13.9 10.1 3.0 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 EST44237.1 - 0.25 12.1 8.5 2.3 9.0 1.6 2.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_13 PF13370.6 EST44237.1 - 1 9.9 15.1 7.4 7.2 3.4 2.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_22 PF17179.4 EST44237.1 - 2.9 8.8 15.0 0.19 12.6 0.5 3.6 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 EST44237.1 - 5.6 8.1 30.6 0.65 11.1 7.5 3.2 3 0 0 3 3 2 0 4Fe-4S binding domain VSP PF03302.13 EST44240.1 - 1.1e-14 54.1 133.4 4.3e-06 25.8 32.4 5.5 1 1 4 5 5 5 5 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST44240.1 - 4.3e-05 23.6 135.9 0.28 11.4 9.4 9.3 1 1 7 8 8 8 7 Furin-like repeat, cysteine-rich Podoplanin PF05808.11 EST44240.1 - 0.048 13.8 0.2 0.078 13.1 0.2 1.3 1 0 0 1 1 1 0 Podoplanin LBP_BPI_CETP PF01273.25 EST44241.1 - 0.0022 17.6 2.0 0.0052 16.4 2.0 1.6 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain DUF1132 PF06575.12 EST44241.1 - 0.012 16.0 0.7 0.11 12.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1132) DUF2442 PF10387.9 EST44241.1 - 0.051 13.9 0.2 0.65 10.3 0.0 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2442) Furin-like_2 PF15913.5 EST44242.1 - 3.4e-11 43.2 129.2 0.00054 20.1 31.0 6.9 1 1 6 7 7 7 6 Furin-like repeat, cysteine-rich VSP PF03302.13 EST44242.1 - 4.9e-08 32.2 139.5 0.0005 19.0 38.7 5.6 1 1 5 6 6 6 4 Giardia variant-specific surface protein Myb_DNA-binding PF00249.31 EST44250.1 - 0.0027 17.8 0.1 0.0036 17.5 0.1 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Recep_L_domain PF01030.24 EST44250.1 - 0.021 14.9 0.1 0.038 14.1 0.1 1.3 1 0 0 1 1 1 0 Receptor L domain DUF3876 PF12992.7 EST44250.1 - 0.049 13.7 0.2 0.06 13.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3876) SHIPPO-rpt PF07004.12 EST44252.1 - 3.8e-16 59.2 21.7 0.0013 19.6 0.1 6.3 6 0 0 6 6 6 5 Sperm-tail PG-rich repeat Caskin1-CID PF16600.5 EST44252.1 - 4.2 8.0 8.8 4 8.1 4.3 3.0 2 1 0 2 2 2 0 Caskin1 CASK-interaction domain Peptidase_C1 PF00112.23 EST44253.1 - 1.2e-54 185.7 3.3 1.2e-54 185.7 3.3 1.6 2 0 0 2 2 2 1 Papain family cysteine protease T4-Gluco-transf PF09198.10 EST44253.1 - 0.048 13.3 0.2 0.44 10.2 0.1 2.3 2 0 0 2 2 2 0 Bacteriophage T4 beta-glucosyltransferase DUF3984 PF13136.6 EST44254.1 - 0.34 10.3 5.1 0.11 11.9 2.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3984) HELP PF03451.14 EST44255.1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 HELP motif Myb_DNA-binding PF00249.31 EST44256.1 - 1.4e-05 25.2 0.0 3.8e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST44256.1 - 0.0071 16.6 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Peptidase_M14 PF00246.24 EST44261.1 - 1.7e-06 28.1 0.0 2.7e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 EST44261.1 - 0.0054 15.8 0.0 0.0083 15.2 0.0 1.2 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Ribosomal_L26 PF16906.5 EST44264.1 - 2.2e-23 82.5 4.1 2.7e-23 82.2 4.1 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal MaoC_dehydrat_N PF13452.6 EST44264.1 - 0.026 14.6 0.1 0.033 14.3 0.1 1.3 1 0 0 1 1 1 0 N-terminal half of MaoC dehydratase KOW PF00467.29 EST44264.1 - 0.12 12.4 5.8 1.2 9.2 5.8 2.3 1 1 0 1 1 1 0 KOW motif zf-U1 PF06220.12 EST44264.1 - 0.82 9.5 5.0 4.8 7.0 0.1 2.5 3 0 0 3 3 3 0 U1 zinc finger Myb_DNA-binding PF00249.31 EST44266.1 - 0.0016 18.6 0.0 0.002 18.3 0.0 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST44266.1 - 0.0029 17.4 0.0 0.0034 17.2 0.0 1.1 1 0 0 1 1 1 1 Myb DNA-binding like DUF1108 PF06531.11 EST44267.1 - 0.0063 16.8 0.0 0.01 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1108) Spike_torovirin PF17072.5 EST44268.1 - 0.65 7.1 3.3 0.99 6.5 3.3 1.1 1 0 0 1 1 1 0 Torovirinae spike glycoprotein YabA PF06156.13 EST44268.1 - 1.9 9.2 8.1 6.7 7.4 0.4 3.4 2 1 1 3 3 3 0 Initiation control protein YabA Fib_alpha PF08702.10 EST44268.1 - 6.9 6.9 8.1 0.4 10.9 0.6 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Ribosomal_S8e PF01201.22 EST44269.1 - 5.6e-43 146.4 2.4 6.8e-43 146.1 2.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e Ribosomal_L27A PF00828.19 EST44271.1 - 1.4e-15 58.1 0.0 2e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A MIEAP PF16026.5 EST44272.1 - 0.02 15.1 0.1 0.03 14.5 0.1 1.3 1 0 0 1 1 1 0 Mitochondria-eating protein SpoVG PF04026.12 EST44273.1 - 0.073 13.3 0.1 0.19 11.9 0.1 1.7 1 0 0 1 1 1 0 SpoVG LRR_8 PF13855.6 EST44274.1 - 6.6e-08 32.2 0.1 0.0073 16.1 0.0 2.4 1 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EST44274.1 - 1.8e-05 25.0 0.0 1.1 9.8 0.0 3.3 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EST44274.1 - 0.00049 20.3 0.2 14 6.7 0.0 5.2 4 2 0 4 4 4 1 Leucine Rich Repeat LRRNT_2 PF08263.12 EST44274.1 - 0.013 15.8 6.8 0.029 14.6 6.8 1.7 1 1 0 1 1 1 0 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 EST44274.1 - 0.07 13.2 2.8 0.81 9.9 0.2 3.3 4 0 0 4 4 4 0 Leucine Rich repeat Myb_DNA-binding PF00249.31 EST44275.1 - 3.3e-13 49.6 3.1 1.1e-08 35.1 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST44275.1 - 1.7e-11 44.2 1.8 9.8e-08 32.1 0.5 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EST44275.1 - 0.024 15.0 1.0 3.2 8.2 0.1 2.5 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain HTH_AsnC-type PF13404.6 EST44275.1 - 0.084 12.7 0.5 8.4 6.3 0.1 2.8 2 1 0 2 2 2 0 AsnC-type helix-turn-helix domain PWI PF01480.17 EST44277.1 - 0.037 14.3 1.4 0.15 12.4 1.4 1.9 1 1 0 1 1 1 0 PWI domain Ribosomal_L30 PF00327.20 EST44278.1 - 0.00072 19.4 0.4 0.0017 18.2 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e zf-CCCH PF00642.24 EST44281.1 - 0.3 11.1 5.2 0.63 10.0 5.2 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Fumble PF03630.14 EST44283.1 - 1.2e-48 166.0 4.2 1.5e-48 165.7 4.2 1.1 1 0 0 1 1 1 1 Fumble RE_HaeII PF09554.10 EST44284.1 - 0.042 13.1 0.0 0.044 13.1 0.0 1.0 1 0 0 1 1 1 0 HaeII restriction endonuclease EnY2 PF10163.9 EST44284.1 - 0.11 12.9 0.5 0.15 12.4 0.1 1.4 2 0 0 2 2 2 0 Transcription factor e(y)2 zf-ZPR1 PF03367.13 EST44286.1 - 2.3 8.0 8.7 1 9.2 5.4 2.1 1 1 1 2 2 2 0 ZPR1 zinc-finger domain PCRF PF03462.18 EST44286.1 - 8.8 6.1 14.9 1.1 9.1 1.0 2.6 2 0 0 2 2 2 0 PCRF domain RIO1 PF01163.22 EST44287.1 - 1.3e-23 83.6 7.5 9.6e-20 71.0 0.0 3.0 3 0 0 3 3 3 2 RIO1 family Rio2_N PF09202.11 EST44287.1 - 5.3e-21 74.6 0.0 1.5e-20 73.2 0.0 1.8 1 0 0 1 1 1 1 Rio2, N-terminal Kdo PF06293.14 EST44287.1 - 0.0053 16.1 0.0 0.28 10.5 0.0 2.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family B277 PF17623.2 EST44287.1 - 0.16 11.0 6.9 0.29 10.2 6.9 1.3 1 0 0 1 1 1 0 Domain of unknown function SKA2 PF16740.5 EST44287.1 - 0.42 10.4 0.1 0.42 10.4 0.1 2.9 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 DUF1160 PF06648.11 EST44287.1 - 1.1 9.3 0.0 1.1 9.3 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1160) Fe_hyd_lg_C PF02906.14 EST44288.1 - 1.6e-64 217.9 1.9 2.6e-64 217.2 1.9 1.3 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fer4 PF00037.27 EST44288.1 - 1.8e-13 49.7 11.5 1.4e-08 34.2 1.7 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EST44288.1 - 1.2e-10 41.7 7.6 1.2e-10 41.7 7.6 2.3 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 EST44288.1 - 9.4e-10 38.5 17.7 4.1e-08 33.3 6.5 3.2 3 1 2 5 5 4 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 EST44288.1 - 5.4e-09 35.7 9.9 3.7e-05 23.6 2.4 2.9 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 EST44288.1 - 8e-09 35.5 8.9 1.9e-05 24.7 0.5 3.1 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 EST44288.1 - 1.5e-07 32.3 6.4 3.7e-05 24.6 0.4 3.3 3 0 0 3 3 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 EST44288.1 - 2.8e-07 30.6 9.4 3.6e-06 27.0 9.4 2.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_15 PF13459.6 EST44288.1 - 3.8e-06 27.5 5.5 0.017 15.8 0.3 3.1 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_22 PF17179.4 EST44288.1 - 4.7e-06 27.4 2.7 0.015 16.1 0.5 2.8 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 EST44288.1 - 8.2e-06 25.6 19.7 0.00032 20.6 4.1 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_8 PF13183.6 EST44288.1 - 8.5e-05 22.9 8.7 0.00086 19.7 9.1 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 EST44288.1 - 0.00016 21.9 6.5 0.023 14.9 0.2 3.6 4 0 0 4 4 4 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 EST44288.1 - 0.00028 21.4 8.7 0.00028 21.4 8.7 2.7 3 1 1 4 4 2 2 4Fe-4S dicluster domain Fe_hyd_SSU PF02256.17 EST44288.1 - 0.00041 20.4 0.0 0.00086 19.3 0.0 1.6 1 0 0 1 1 1 1 Iron hydrogenase small subunit Fer4_4 PF12800.7 EST44288.1 - 0.0022 18.4 1.6 0.0022 18.4 1.6 3.3 3 0 0 3 3 2 1 4Fe-4S binding domain Fer4_13 PF13370.6 EST44288.1 - 0.0027 18.2 7.2 0.26 11.8 0.9 2.8 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 EST44288.1 - 0.054 14.4 7.6 0.054 14.4 7.6 3.6 3 0 0 3 3 3 0 4Fe-4S binding domain ETF_QO PF05187.13 EST44288.1 - 0.93 9.7 4.0 9 6.5 0.2 2.8 3 0 0 3 3 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Ribosomal_S11 PF00411.19 EST44292.1 - 7.4e-32 110.0 1.1 9.3e-32 109.7 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Polysacc_synt_4 PF04669.13 EST44293.1 - 1.7e-09 37.5 0.0 1.1e-05 25.0 0.0 2.1 1 1 1 2 2 2 2 Polysaccharide biosynthesis DP PF08781.10 EST44293.1 - 0.027 14.4 0.2 0.039 13.8 0.2 1.4 1 0 0 1 1 1 0 Transcription factor DP Ribosomal_S11 PF00411.19 EST44294.1 - 5.5e-10 39.6 0.2 5.8e-10 39.5 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S11 LRR_8 PF13855.6 EST44295.1 - 0.00052 19.7 3.7 0.0029 17.3 0.5 2.5 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 EST44295.1 - 0.0021 18.4 7.0 0.39 11.2 0.8 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) Dscam_C PF12355.8 EST44296.1 - 0.012 16.6 1.0 0.036 15.0 1.0 1.9 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal DUF2715 PF10895.8 EST44297.1 - 0.15 11.6 6.0 0.34 10.5 6.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2715) DUF2788 PF10981.8 EST44299.1 - 0.17 11.9 0.5 0.28 11.2 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2788) Amino_oxidase PF01593.24 EST44301.1 - 7.3e-09 35.4 0.0 9.5e-08 31.7 0.0 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EST44301.1 - 4.5e-06 26.8 1.3 5.3e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EST44301.1 - 0.00016 20.9 0.0 0.00041 19.6 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EST44301.1 - 0.00018 21.2 0.0 0.0099 15.5 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EST44301.1 - 0.00039 19.2 0.0 0.0044 15.8 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 EST44301.1 - 0.0025 17.1 0.0 0.0087 15.3 0.0 1.8 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 EST44301.1 - 0.059 12.7 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase GMC_oxred_N PF00732.19 EST44301.1 - 0.089 12.1 0.1 0.25 10.7 0.1 1.7 2 0 0 2 2 2 0 GMC oxidoreductase Pyr_redox_2 PF07992.14 EST44301.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase YL1_C PF08265.11 EST44302.1 - 1.8e-06 27.6 1.0 2.8e-06 27.0 1.0 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain FRD2 PF03197.13 EST44306.1 - 0.1 12.9 0.2 3.7 7.9 0.0 2.6 2 0 0 2 2 2 0 Bacteriophage FRD2 protein RCS1 PF07326.11 EST44309.1 - 0.027 14.4 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 Regulator of chromosome segregation 1 Actin PF00022.19 EST44310.1 - 1.3e-130 435.7 0.0 2.1e-129 431.7 0.0 1.9 1 1 0 1 1 1 1 Actin SPOB_ab PF14682.6 EST44310.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal MreB_Mbl PF06723.13 EST44310.1 - 0.15 10.9 0.0 0.5 9.1 0.0 1.7 2 0 0 2 2 2 0 MreB/Mbl protein Nup35_RRM_2 PF14605.6 EST44311.1 - 0.14 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Ribosomal_S27e PF01667.17 EST44312.1 - 9.3e-11 41.3 4.5 1.1e-10 41.0 4.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 Cytomega_TRL10 PF06084.11 EST44312.1 - 0.15 12.0 2.7 0.17 11.9 2.7 1.1 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein TF_AP-2 PF03299.14 EST44313.1 - 0.017 15.1 3.8 0.029 14.4 3.8 1.4 1 0 0 1 1 1 0 Transcription factor AP-2 Baculo_PEP_C PF04513.12 EST44313.1 - 0.033 14.2 24.8 0.035 14.2 18.2 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 EST44313.1 - 0.12 12.5 13.9 0.084 12.9 7.5 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) HAP1_N PF04849.13 EST44313.1 - 0.25 10.5 18.5 0.42 9.8 18.2 1.5 1 1 0 1 1 1 0 HAP1 N-terminal conserved region DUF730 PF05325.11 EST44313.1 - 0.52 10.3 2.6 1.5 8.9 0.1 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF730) MCPVI PF02993.14 EST44313.1 - 1.9 8.3 5.3 0.85 9.4 2.4 1.7 1 1 1 2 2 2 0 Minor capsid protein VI COMP PF11598.8 EST44313.1 - 2 8.9 9.1 14 6.2 2.4 4.1 2 1 1 3 3 3 0 Cartilage oligomeric matrix protein SF1-HH PF16275.5 EST44313.1 - 4.4 7.7 6.6 2 8.8 1.3 2.5 1 1 1 2 2 2 0 Splicing factor 1 helix-hairpin domain Prominin PF05478.11 EST44313.1 - 4.8 5.0 18.2 5.9 4.7 14.4 1.7 1 1 0 1 1 1 0 Prominin RL10P_insert PF17777.1 EST44314.1 - 7.6e-20 70.7 0.2 1.9e-19 69.4 0.1 1.8 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 EST44314.1 - 1.1e-18 67.2 0.7 1.7e-18 66.5 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Ubiquitin_2 PF14560.6 EST44315.1 - 0.0096 16.4 0.2 0.014 15.8 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain Phage_hub_GP28 PF11110.8 EST44315.1 - 0.086 12.7 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 Baseplate hub distal subunit Ribosomal_S19e PF01090.19 EST44316.1 - 6.7e-47 158.6 0.1 7.4e-47 158.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e RuvB_C PF05491.13 EST44316.1 - 0.00011 22.0 0.2 0.0027 17.5 0.2 2.4 1 1 0 1 1 1 1 RuvB C-terminal winged helix domain FokI_C PF02980.16 EST44316.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease FokI, catalytic domain Actin PF00022.19 EST44317.1 - 1.3e-130 435.7 0.0 2.1e-129 431.7 0.0 1.9 1 1 0 1 1 1 1 Actin SPOB_ab PF14682.6 EST44317.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal MreB_Mbl PF06723.13 EST44317.1 - 0.15 10.9 0.0 0.5 9.1 0.0 1.7 2 0 0 2 2 2 0 MreB/Mbl protein Ribosomal_S8 PF00410.19 EST44318.1 - 5.9e-20 71.5 0.0 7.5e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 HTH_Tnp_4 PF13613.6 EST44318.1 - 0.15 11.8 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease DUF3719 PF12516.8 EST44318.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3719) Ribosomal_S6e PF01092.19 EST44320.1 - 2.4e-39 134.2 0.7 4.4e-39 133.3 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S6e Pkinase PF00069.25 EST44321.1 - 7.5e-36 123.8 0.0 1.3e-35 123.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST44321.1 - 3.4e-15 56.0 0.0 8.5e-15 54.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Ras PF00071.22 EST44322.1 - 1.4e-49 167.8 0.3 1.8e-49 167.5 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EST44322.1 - 5.2e-29 100.9 0.0 8.2e-29 100.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EST44322.1 - 3e-10 39.8 0.0 4.6e-10 39.2 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EST44322.1 - 0.01 15.4 0.5 0.047 13.2 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain RNA_helicase PF00910.22 EST44322.1 - 0.022 15.2 0.4 0.13 12.6 0.4 2.1 1 1 0 1 1 1 0 RNA helicase MSP PF01716.18 EST44322.1 - 0.03 13.5 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 Manganese-stabilising protein / photosystem II polypeptide SRPRB PF09439.10 EST44322.1 - 0.043 13.3 0.0 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Aa_trans PF01490.18 EST44323.1 - 3.4e-47 161.1 42.0 4e-47 160.8 42.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein UCH PF00443.29 EST44325.1 - 1.7e-26 93.3 11.3 1.7e-26 93.3 11.3 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF5495 PF17599.2 EST44325.1 - 0.0082 16.4 0.9 0.037 14.3 0.2 2.5 2 0 0 2 2 2 1 Family of unknown function (DUF5495) Ribosomal_L2_C PF03947.18 EST44326.1 - 7.4e-40 136.1 1.4 1.2e-39 135.4 1.4 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EST44326.1 - 3.7e-12 46.0 0.1 9e-12 44.8 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Apolipoprotein PF01442.18 EST44327.1 - 0.23 11.3 40.9 0.14 12.0 3.0 4.2 2 2 1 3 3 3 0 Apolipoprotein A1/A4/E domain DUF1128 PF06569.11 EST44327.1 - 0.31 11.1 7.7 0.27 11.3 1.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1128) ApoO PF09769.9 EST44327.1 - 1.2 9.1 22.8 0.36 10.8 2.3 5.0 4 1 0 5 5 5 0 Apolipoprotein O ComC PF03047.14 EST44327.1 - 7.4 6.5 7.9 40 4.2 4.7 3.4 2 1 0 2 2 2 0 COMC family Dynactin_p22 PF07426.11 EST44328.1 - 0.00022 21.1 2.5 0.00028 20.8 1.6 1.6 1 1 0 1 1 1 1 Dynactin subunit p22 AbrB_C PF18277.1 EST44328.1 - 0.2 11.3 1.5 0.41 10.3 0.2 2.1 2 0 0 2 2 2 0 AbrB C-terminal domain L27_2 PF09045.10 EST44328.1 - 4.3 7.4 8.3 0.3 11.1 2.5 2.2 2 0 0 2 2 2 0 L27_2 WD40 PF00400.32 EST44330.1 - 2.9e-11 43.7 0.1 0.00026 21.7 0.1 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF1899 PF08953.11 EST44330.1 - 2.1e-06 27.5 0.0 4.6e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) ANAPC4_WD40 PF12894.7 EST44330.1 - 0.0063 16.8 0.2 14 6.1 0.0 3.5 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EST44330.1 - 0.063 12.2 0.1 1.7 7.5 0.0 2.4 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RNA_pol_Rpb2_45 PF10385.9 EST44330.1 - 0.12 12.6 0.2 0.27 11.5 0.2 1.5 1 0 0 1 1 1 0 RNA polymerase beta subunit external 1 domain CM_2 PF01817.21 EST44331.1 - 0.037 14.4 0.2 0.047 14.0 0.2 1.2 1 0 0 1 1 1 0 Chorismate mutase type II SlyX PF04102.12 EST44331.1 - 0.25 12.0 4.3 0.15 12.7 2.8 1.4 1 1 0 1 1 1 0 SlyX zf-A20 PF01754.16 EST44338.1 - 0.14 12.1 0.1 0.14 12.1 0.1 2.1 3 0 0 3 3 3 0 A20-like zinc finger Myb_DNA-binding PF00249.31 EST44339.1 - 4.7e-07 29.9 0.3 6.2e-07 29.5 0.3 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST44339.1 - 1e-05 25.7 0.2 1.3e-05 25.3 0.2 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EST44339.1 - 0.0013 18.8 0.3 0.0019 18.4 0.3 1.3 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 EST44339.1 - 0.064 13.2 0.1 0.091 12.7 0.1 1.2 1 0 0 1 1 1 0 Myb DNA-binding like SmpA_OmlA PF04355.13 EST44339.1 - 0.17 11.7 1.3 2.8 7.8 1.3 2.3 1 1 0 1 1 1 0 SmpA / OmlA family LRR19-TM PF15176.6 EST44341.1 - 0.18 11.8 0.1 0.37 10.8 0.0 1.5 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain UQ_con PF00179.26 EST44343.1 - 5.7e-53 178.3 0.0 6.4e-53 178.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EST44343.1 - 0.00083 19.1 0.0 0.00098 18.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EST44343.1 - 0.0059 16.9 0.0 0.0077 16.5 0.0 1.3 1 0 0 1 1 1 1 RWD domain Sec23_trunk PF04811.15 EST44345.1 - 1.7e-21 76.9 5.0 3.4e-21 75.9 5.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EST44345.1 - 1.1e-10 42.1 0.0 1.1e-10 42.1 0.0 2.8 3 0 0 3 3 3 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EST44345.1 - 2.2e-08 34.0 3.2 6.2e-08 32.6 3.2 1.9 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger DUF3631 PF12307.8 EST44349.1 - 0.12 12.6 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3631) MFS_1 PF07690.16 EST44354.1 - 1.8e-19 69.9 40.1 2.9e-19 69.2 38.4 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily SATase_N PF06426.14 EST44355.1 - 0.2 12.0 1.0 5.6 7.4 0.0 3.3 4 0 0 4 4 4 0 Serine acetyltransferase, N-terminal Microcin PF03526.13 EST44356.1 - 0.08 12.8 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Colicin E1 (microcin) immunity protein SHIPPO-rpt PF07004.12 EST44359.1 - 4.3 8.4 41.7 0.16 13.0 1.2 7.7 8 1 0 8 8 8 0 Sperm-tail PG-rich repeat Mem_trans PF03547.18 EST44361.1 - 1.1e-09 37.2 27.8 2.2e-06 26.3 11.4 2.0 1 1 1 2 2 2 2 Membrane transport protein DUF3989 PF13150.6 EST44361.1 - 0.76 9.6 3.3 2 8.2 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) CPP1-like PF11833.8 EST44361.1 - 6.7 6.3 11.9 2.7 7.6 5.0 2.5 2 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like WD40 PF00400.32 EST44362.1 - 7.1e-11 42.5 6.9 0.0088 16.9 0.4 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EST44362.1 - 3.8e-08 33.5 0.0 0.053 13.8 0.0 4.4 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EST44362.1 - 0.065 12.2 0.3 0.39 9.6 0.1 2.2 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PH_TFIIH PF08567.11 EST44368.1 - 0.065 13.6 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain Ubiquitin_2 PF14560.6 EST44370.1 - 0.1 13.1 3.6 0.094 13.2 1.2 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain AAA PF00004.29 EST44372.1 - 2.2e-41 141.4 0.0 5.2e-41 140.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EST44372.1 - 6e-14 51.6 0.4 4.1e-13 48.9 0.1 2.3 2 0 0 2 2 2 1 AAA+ lid domain Vps4_C PF09336.10 EST44372.1 - 1.3e-06 28.3 0.4 3.4e-06 26.9 0.3 1.8 1 1 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.14 EST44372.1 - 0.026 14.6 0.5 0.2 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) CDC48_N PF02359.18 EST44373.1 - 6.4e-18 64.7 0.0 9.1e-18 64.2 0.0 1.3 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain Molydop_binding PF01568.21 EST44373.1 - 0.012 15.7 0.0 0.023 14.7 0.0 1.5 1 1 0 1 1 1 0 Molydopterin dinucleotide binding domain Med31 PF05669.12 EST44375.1 - 1e-18 67.1 5.4 1e-18 67.1 5.4 2.2 1 1 1 2 2 2 1 SOH1 DUF3822 PF12864.7 EST44376.1 - 0.21 10.7 0.0 0.27 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3822) Myb_DNA-bind_6 PF13921.6 EST44377.1 - 4.7e-05 23.5 0.0 9.6e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EST44377.1 - 0.00022 21.3 0.0 0.00082 19.5 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain AAA_6 PF12774.7 EST44378.1 - 0.63 8.9 5.5 3.1 6.7 1.5 2.0 1 1 1 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Pkinase PF00069.25 EST44379.1 - 6.4e-64 215.9 0.0 8e-64 215.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST44379.1 - 1.9e-33 115.9 0.0 4.3e-33 114.7 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EST44379.1 - 1.3e-05 24.4 0.2 2.2e-05 23.6 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EST44379.1 - 0.0006 18.7 0.0 0.0015 17.4 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EST44379.1 - 0.032 14.2 0.0 0.6 10.0 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EST44379.1 - 0.034 13.5 0.2 0.11 11.8 0.2 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CTP_synth_N PF06418.14 EST44381.1 - 2.1e-21 76.4 0.4 3.7e-21 75.6 0.4 1.4 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 EST44381.1 - 3.4e-12 46.5 0.2 6.3e-12 45.7 0.2 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Myb_DNA-binding PF00249.31 EST44382.1 - 6.6e-09 35.8 2.6 0.001 19.2 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST44382.1 - 2.9e-06 27.4 8.1 0.014 15.6 0.3 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain NLE PF08154.12 EST44383.1 - 4.8e-08 33.4 3.1 1e-07 32.3 3.1 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain WD40 PF00400.32 EST44383.1 - 0.0057 17.5 6.3 46 5.1 0.0 5.4 5 1 0 5 5 5 1 WD domain, G-beta repeat PQQ_3 PF13570.6 EST44383.1 - 0.014 15.9 0.1 0.15 12.6 0.0 2.7 3 0 0 3 3 3 0 PQQ-like domain PA14 PF07691.12 EST44384.1 - 0.11 12.3 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 PA14 domain RHH_7 PF16777.5 EST44385.1 - 0.33 11.4 2.3 13 6.3 0.2 2.5 2 0 0 2 2 2 0 Transcriptional regulator, RHH-like, CopG Ribosomal_L7Ae PF01248.26 EST44386.1 - 3e-22 78.2 0.4 7e-22 77.0 0.3 1.6 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF4525 PF15027.6 EST44386.1 - 0.084 12.6 0.2 0.6 9.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4525) Tox-PLDMTX PF15645.6 EST44386.1 - 0.12 12.7 0.2 0.21 11.8 0.2 1.4 1 0 0 1 1 1 0 Dermonecrotoxin of the Papain-like fold DUF446 PF04287.12 EST44386.1 - 0.15 12.2 0.2 23 5.1 0.1 2.6 2 0 0 2 2 2 0 tRNA pseudouridine synthase C Radial_spoke_3 PF06098.11 EST44387.1 - 2.8e-61 207.3 15.4 3.2e-61 207.1 15.4 1.0 1 0 0 1 1 1 1 Radial spoke protein 3 Macoilin PF09726.9 EST44387.1 - 0.0041 15.7 6.6 0.0057 15.3 6.6 1.3 1 0 0 1 1 1 1 Macoilin family DUF5564 PF17719.1 EST44387.1 - 0.009 16.1 1.9 0.022 14.9 1.6 1.8 1 1 0 1 1 1 1 Family of unknown function (DUF5564) NINJA_B PF16136.5 EST44387.1 - 0.22 11.9 6.8 0.043 14.2 2.7 1.9 2 0 0 2 2 2 0 Putative nuclear localisation signal TRAP-gamma PF07074.12 EST44387.1 - 1.1 8.8 3.1 1.7 8.2 3.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF4606 PF15379.6 EST44387.1 - 2.6 8.4 8.5 5.8 7.2 6.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4606) Putative_PNPOx PF01243.20 EST44388.1 - 3.8e-05 23.8 0.0 5.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase BPTA PF17044.5 EST44388.1 - 0.05 13.5 0.2 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Borrelial persistence in ticks protein A Pyrid_ox_like PF16242.5 EST44388.1 - 0.065 12.8 0.0 0.087 12.4 0.0 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like DUF5542 PF17696.1 EST44389.1 - 0.086 13.0 3.1 0.24 11.5 3.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5542) DUF3169 PF11368.8 EST44390.1 - 0.00072 19.1 0.3 0.00082 19.0 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3169) EGF_2 PF07974.13 EST44390.1 - 0.37 11.2 4.8 0.66 10.4 4.8 1.4 1 0 0 1 1 1 0 EGF-like domain DUF2769 PF10967.8 EST44390.1 - 4.6 8.0 7.8 0.26 12.0 2.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2769) DUF5030 PF16433.5 EST44392.1 - 0.082 12.2 1.9 1.2 8.4 0.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5030) Tmemb_40 PF10160.9 EST44392.1 - 0.11 11.9 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein Geminin PF07412.12 EST44393.1 - 0.0058 16.4 1.5 0.0058 16.4 1.5 2.2 2 0 0 2 2 2 1 Geminin Fez1 PF06818.15 EST44393.1 - 0.075 13.5 7.3 0.072 13.5 6.2 1.5 1 1 0 1 1 1 0 Fez1 GrpE PF01025.19 EST44393.1 - 0.5 10.0 12.9 0.077 12.7 5.4 2.1 2 0 0 2 2 2 0 GrpE YabA PF06156.13 EST44393.1 - 1.7 9.3 14.5 6.1 7.5 7.9 2.3 2 0 0 2 2 2 0 Initiation control protein YabA CC2-LZ PF16516.5 EST44393.1 - 2.5 8.5 13.2 1.4 9.3 6.5 2.6 2 1 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator CENP-H PF05837.12 EST44393.1 - 2.8 8.4 12.3 1.5 9.3 7.4 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Csm1_N PF18504.1 EST44393.1 - 3.2 8.2 14.4 5.8 7.3 7.9 3.3 2 1 1 3 3 3 0 Csm1 N-terminal domain DNA_pol_D_N PF18018.1 EST44394.1 - 0.013 15.6 0.2 0.029 14.5 0.2 1.5 1 0 0 1 1 1 0 DNA polymerase delta subunit OB-fold domain FliS PF02561.14 EST44395.1 - 0.053 13.8 1.0 0.088 13.1 0.4 1.7 1 1 1 2 2 2 0 Flagellar protein FliS FRB_dom PF08771.11 EST44395.1 - 0.082 13.3 1.9 0.1 13.1 1.9 1.2 1 0 0 1 1 1 0 FKBP12-rapamycin binding domain Pox_A_type_inc PF04508.12 EST44396.1 - 0.096 12.6 1.1 0.25 11.2 1.1 1.8 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat LMBR1 PF04791.16 EST44396.1 - 0.28 10.0 4.6 0.34 9.8 4.6 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein PKcGMP_CC PF16808.5 EST44396.1 - 0.48 10.3 10.9 1.2 9.1 1.4 3.6 3 1 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Exonuc_VII_L PF02601.15 EST44396.1 - 0.5 9.9 6.8 0.66 9.5 6.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Fib_alpha PF08702.10 EST44396.1 - 1.3 9.2 15.8 19 5.4 0.0 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family AAA_2 PF07724.14 EST44397.1 - 2.6e-46 157.9 0.9 2.1e-45 154.9 0.0 2.9 3 1 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EST44397.1 - 2.4e-28 98.1 0.3 2.4e-28 98.1 0.3 2.7 3 1 0 3 3 2 1 AAA lid domain AAA PF00004.29 EST44397.1 - 6.2e-23 81.7 0.1 3.6e-11 43.6 0.0 3.5 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EST44397.1 - 1.5e-14 54.2 0.4 5e-10 39.5 0.0 3.8 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.9 EST44397.1 - 6.6e-12 45.3 0.3 6e-11 42.2 0.0 2.7 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.6 EST44397.1 - 8.9e-12 45.7 4.9 8.8e-06 26.2 0.1 3.9 3 2 1 4 4 4 2 AAA ATPase domain Clp_N PF02861.20 EST44397.1 - 7.2e-11 42.1 0.0 2.3e-05 24.4 0.0 2.8 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component Sigma54_activat PF00158.26 EST44397.1 - 3.5e-09 36.6 0.4 3e-06 27.0 0.0 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 EST44397.1 - 1.6e-07 31.4 0.0 0.011 15.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 EST44397.1 - 1.9e-07 31.0 0.1 0.031 14.0 0.0 3.2 3 0 0 3 3 3 2 IstB-like ATP binding protein ATPase_2 PF01637.18 EST44397.1 - 6.3e-07 29.5 0.0 0.047 13.6 0.0 3.8 3 0 0 3 3 3 2 ATPase domain predominantly from Archaea AAA_7 PF12775.7 EST44397.1 - 8e-07 28.8 0.0 0.00081 18.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_22 PF13401.6 EST44397.1 - 6.2e-06 26.5 1.4 0.036 14.4 0.1 3.8 3 2 0 3 3 2 2 AAA domain AAA_18 PF13238.6 EST44397.1 - 8.5e-06 26.3 0.0 0.11 13.1 0.0 3.1 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EST44397.1 - 1.5e-05 25.3 1.2 0.12 12.8 0.0 3.9 4 0 0 4 4 3 1 RNA helicase DUF815 PF05673.13 EST44397.1 - 1.9e-05 24.0 0.2 0.24 10.6 0.1 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF815) TniB PF05621.11 EST44397.1 - 2.5e-05 23.8 0.0 0.047 13.1 0.0 3.8 2 1 0 2 2 2 1 Bacterial TniB protein NACHT PF05729.12 EST44397.1 - 3.4e-05 23.8 0.0 0.37 10.7 0.0 2.8 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.6 EST44397.1 - 8.7e-05 22.8 0.5 0.51 10.6 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.6 EST44397.1 - 0.00013 22.2 0.0 0.059 13.5 0.0 3.2 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 EST44397.1 - 0.00013 22.0 0.1 0.42 10.6 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 EST44397.1 - 0.00014 21.6 0.0 0.017 14.9 0.0 2.9 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase RsgA_GTPase PF03193.16 EST44397.1 - 0.00015 21.7 0.3 0.27 11.1 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_3 PF07726.11 EST44397.1 - 0.00031 20.6 0.2 0.07 13.0 0.0 3.7 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Torsin PF06309.11 EST44397.1 - 0.00051 20.1 0.0 0.0029 17.7 0.0 2.1 2 0 0 2 2 2 1 Torsin Zeta_toxin PF06414.12 EST44397.1 - 0.00057 19.2 0.0 0.013 14.8 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_24 PF13479.6 EST44397.1 - 0.0019 17.9 0.0 0.24 11.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EST44397.1 - 0.0024 18.4 0.5 0.089 13.3 0.0 3.1 3 0 0 3 3 3 1 ABC transporter Roc PF08477.13 EST44397.1 - 0.0033 17.6 0.0 0.43 10.8 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Bac_DnaA PF00308.18 EST44397.1 - 0.0052 16.7 0.0 0.28 11.0 0.0 2.6 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_19 PF13245.6 EST44397.1 - 0.0083 16.5 0.1 0.93 9.8 0.0 3.3 3 0 0 3 3 2 1 AAA domain TrwB_AAD_bind PF10412.9 EST44397.1 - 0.0091 14.9 0.1 6.3 5.6 0.0 3.2 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain Mg_chelatase PF01078.21 EST44397.1 - 0.0096 15.3 0.0 0.31 10.4 0.0 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI ResIII PF04851.15 EST44397.1 - 0.011 15.7 0.1 2.8 7.9 0.0 3.7 3 1 1 4 4 4 0 Type III restriction enzyme, res subunit AAA_25 PF13481.6 EST44397.1 - 0.015 14.9 0.2 2.2 7.8 0.1 3.2 2 1 0 2 2 2 0 AAA domain RuvB_N PF05496.12 EST44397.1 - 0.021 14.5 0.1 2.7 7.7 0.0 3.3 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain PAN_2 PF08276.11 EST44397.1 - 0.045 13.9 0.2 0.11 12.7 0.2 1.6 1 0 0 1 1 1 0 PAN-like domain SRP54 PF00448.22 EST44397.1 - 0.055 13.1 0.0 15 5.2 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Rad17 PF03215.15 EST44397.1 - 0.056 13.4 0.0 2.1 8.3 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain APS_kinase PF01583.20 EST44397.1 - 0.06 13.2 0.1 2.1 8.2 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_30 PF13604.6 EST44397.1 - 0.065 13.0 0.0 1.1 8.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 EST44397.1 - 0.075 12.7 0.7 4.1 7.0 0.0 3.1 2 2 1 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.9 EST44397.1 - 0.12 12.1 0.0 0.77 9.5 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 EST44397.1 - 0.15 12.0 1.2 4.4 7.2 0.0 3.4 3 0 0 3 3 3 0 NTPase AAA_29 PF13555.6 EST44397.1 - 0.16 11.8 0.1 20 5.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF87 PF01935.17 EST44397.1 - 0.86 9.7 5.4 1.2 9.1 0.0 3.4 3 1 0 3 3 3 0 Helicase HerA, central domain Cyd_oper_YbgE PF09600.10 EST44398.1 - 0.024 15.0 4.9 0.067 13.6 0.3 2.4 2 1 1 3 3 3 0 Cyd operon protein YbgE (Cyd_oper_YbgE) EamA PF00892.20 EST44399.1 - 0.0006 20.0 25.1 0.00062 20.0 6.9 3.2 2 2 0 2 2 2 2 EamA-like transporter family DUF2070 PF09843.9 EST44399.1 - 0.072 11.4 7.3 0.12 10.7 7.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) SLC35F PF06027.12 EST44399.1 - 0.26 10.8 15.5 0.46 9.9 15.1 1.7 1 1 0 1 1 1 0 Solute carrier family 35 DUF5542 PF17696.1 EST44400.1 - 0.084 13.0 3.1 0.24 11.6 3.1 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5542) TNF PF00229.18 EST44402.1 - 0.041 13.8 0.2 0.11 12.4 0.2 1.8 1 0 0 1 1 1 0 TNF(Tumour Necrosis Factor) family DUF1765 PF08578.10 EST44402.1 - 0.16 12.5 5.4 0.18 12.3 3.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1765) CENP-F_leu_zip PF10473.9 EST44404.1 - 0.22 11.6 19.7 0.84 9.7 9.3 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4538 PF15061.6 EST44404.1 - 0.37 10.6 2.5 4 7.3 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) ATG16 PF08614.11 EST44404.1 - 0.39 10.9 16.2 0.79 9.9 15.6 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) AAA_23 PF13476.6 EST44404.1 - 3.7 8.0 17.5 0.26 11.8 12.7 1.6 2 0 0 2 2 2 0 AAA domain EF-hand_7 PF13499.6 EST44405.1 - 6.6e-07 29.7 10.6 1.9 9.0 0.0 6.8 4 2 2 6 6 6 4 EF-hand domain pair EF-hand_6 PF13405.6 EST44405.1 - 1.7e-05 24.4 4.4 19 5.5 0.1 7.8 8 2 1 9 9 9 0 EF-hand domain LPD39 PF18858.1 EST44405.1 - 0.003 17.7 3.6 30 4.6 0.0 5.0 6 0 0 6 6 6 0 Large polyvalent protein associated domain 39 PuR_N PF09182.10 EST44405.1 - 0.0051 16.7 0.6 0.55 10.2 0.1 2.8 2 0 0 2 2 2 1 Bacterial purine repressor, N-terminal H-kinase_dim PF02895.14 EST44405.1 - 0.07 13.5 7.8 4.9 7.6 0.0 4.6 4 1 0 4 4 4 0 Signal transducing histidine kinase, homodimeric domain EF-hand_5 PF13202.6 EST44405.1 - 0.097 12.2 0.4 33 4.2 0.1 3.6 2 0 0 2 2 2 0 EF hand NdhL PF10716.9 EST44405.1 - 0.099 12.6 2.0 10 6.1 0.1 3.7 4 0 0 4 4 4 0 NADH dehydrogenase transmembrane subunit PPR_2 PF13041.6 EST44405.1 - 0.35 11.1 6.0 53 4.1 0.2 3.9 4 0 0 4 4 4 0 PPR repeat family PAH PF02671.21 EST44405.1 - 0.36 11.0 2.8 3.2 8.0 0.0 3.9 3 0 0 3 3 3 0 Paired amphipathic helix repeat DUF1896 PF08989.10 EST44405.1 - 0.54 10.4 6.4 8.6 6.5 0.1 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF1896) Histone PF00125.24 EST44407.1 - 5.5e-07 30.0 0.4 7.9e-07 29.5 0.4 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EST44407.1 - 0.00018 21.7 0.2 0.0029 17.8 0.1 2.3 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF3834 PF12916.7 EST44407.1 - 0.001 18.3 0.0 0.0011 18.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3834) SLC35F PF06027.12 EST44409.1 - 2.1e-07 30.8 16.5 5.7e-07 29.3 16.5 1.7 1 1 0 1 1 1 1 Solute carrier family 35 eIF-5_eIF-2B PF01873.17 EST44410.1 - 1.4e-25 89.4 2.3 2.2e-24 85.6 0.0 2.9 3 0 0 3 3 3 1 Domain found in IF2B/IF5 Zn_Tnp_IS1595 PF12760.7 EST44410.1 - 0.024 14.6 0.5 0.024 14.6 0.5 1.9 2 0 0 2 2 2 0 Transposase zinc-ribbon domain tRNA-synt_1f PF01921.18 EST44410.1 - 0.068 12.1 0.2 0.11 11.4 0.2 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) W2 PF02020.18 EST44410.1 - 0.072 13.2 2.1 0.13 12.4 0.3 2.3 2 0 0 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon zf_C2H2_13 PF18508.1 EST44410.1 - 0.12 12.0 1.7 2.1 8.0 0.0 2.5 2 0 0 2 2 2 0 Zinc finger domain Ldh_1_N PF00056.23 EST44412.1 - 1.2e-30 106.4 0.0 1.9e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 EST44412.1 - 1.8e-18 67.0 0.0 3e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain RRM_1 PF00076.22 EST44413.1 - 3.7e-08 33.1 3.2 5.8e-05 22.8 0.1 5.2 5 0 0 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arabinose_bd PF12625.7 EST44414.1 - 0.13 12.3 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Arabinose-binding domain of AraC transcription regulator, N-term SieB PF14163.6 EST44414.1 - 0.61 9.6 5.1 2.7 7.5 5.1 2.1 1 0 0 1 1 1 0 Super-infection exclusion protein B LisH PF08513.11 EST44415.1 - 0.0019 18.1 0.0 0.0051 16.7 0.0 1.8 1 0 0 1 1 1 1 LisH IlvC PF01450.19 EST44415.1 - 0.079 13.2 0.0 0.15 12.4 0.0 1.5 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Robl_LC7 PF03259.17 EST44416.1 - 7.8e-14 51.2 0.0 8.6e-14 51.1 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain DUF2937 PF11157.8 EST44419.1 - 0.88 9.3 5.6 0.12 12.0 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Annexin PF00191.20 EST44420.1 - 6.5e-42 141.4 0.3 7.3e-13 48.4 0.0 5.1 5 0 0 5 5 5 5 Annexin DUF3524 PF12038.8 EST44420.1 - 0.016 15.0 0.2 0.28 11.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3524) OGG_N PF07934.12 EST44420.1 - 0.038 14.1 0.2 0.064 13.4 0.2 1.3 1 0 0 1 1 1 0 8-oxoguanine DNA glycosylase, N-terminal domain AcetDehyd-dimer PF09290.11 EST44420.1 - 0.052 13.7 0.0 0.095 12.9 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation DUF2255 PF10012.9 EST44420.1 - 1.2 9.3 3.7 30 4.8 0.3 3.1 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2255) DUF3153 PF11353.8 EST44422.1 - 0.0015 18.2 0.3 0.0025 17.4 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3153) AbiTii PF18864.1 EST44422.1 - 0.037 14.2 0.9 0.12 12.5 0.3 2.0 1 1 1 2 2 2 0 AbiTii KELK PF15796.5 EST44422.1 - 0.36 11.3 13.6 0.25 11.8 1.4 3.2 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Med9 PF07544.13 EST44422.1 - 0.51 10.4 7.0 3.7 7.7 1.1 3.1 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 COG2 PF06148.11 EST44422.1 - 0.87 9.7 7.7 0.44 10.6 0.9 2.5 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 UPF0122 PF04297.14 EST44422.1 - 2.6 8.3 7.7 1.5 9.1 1.0 2.1 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like YabA PF06156.13 EST44422.1 - 5.2 7.8 8.2 2.8 8.6 1.4 2.4 2 0 0 2 2 2 0 Initiation control protein YabA HAUS6_N PF14661.6 EST44422.1 - 6.3 6.3 9.9 0.63 9.6 1.4 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Myb_DNA-binding PF00249.31 EST44423.1 - 1e-05 25.6 0.1 1.6e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST44423.1 - 0.00012 22.3 0.2 0.00014 22.0 0.2 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZapD PF07072.11 EST44423.1 - 0.04 13.7 0.1 0.042 13.6 0.1 1.1 1 0 0 1 1 1 0 Cell division protein Ras PF00071.22 EST44424.1 - 1.4e-14 54.0 0.0 1.6e-14 53.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EST44424.1 - 4e-08 33.5 0.0 5.6e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EST44424.1 - 0.0032 16.9 0.0 0.0049 16.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 EST44424.1 - 0.0064 16.0 0.0 0.0085 15.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EST44424.1 - 0.0069 16.5 0.0 0.013 15.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EST44424.1 - 0.11 12.7 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 EST44424.1 - 0.12 11.8 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AMP-binding PF00501.28 EST44425.1 - 4.1e-54 183.8 0.0 2.8e-52 177.7 0.0 2.6 1 1 0 1 1 1 1 AMP-binding enzyme DUF1069 PF06370.11 EST44427.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1069) DUF3332 PF11810.8 EST44428.1 - 0.11 12.1 0.6 0.14 11.8 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) Fe-ADH PF00465.19 EST44429.1 - 1.3e-68 231.4 0.0 1.6e-68 231.2 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EST44429.1 - 3.1e-05 23.8 0.0 0.00058 19.6 0.0 2.1 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase NolV PF06635.12 EST44430.1 - 0.15 11.4 0.1 0.25 10.7 0.1 1.3 1 0 0 1 1 1 0 Nodulation protein NolV Ras PF00071.22 EST44431.1 - 5.3e-55 185.4 0.0 6.6e-55 185.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EST44431.1 - 4.4e-32 110.8 0.0 6.9e-32 110.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EST44431.1 - 4.2e-09 36.1 0.0 5.5e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EST44431.1 - 6.2e-05 23.1 0.0 0.0032 17.5 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EST44431.1 - 0.0068 15.8 0.0 0.0084 15.5 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EST44431.1 - 0.053 13.0 0.0 0.23 11.0 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain PIH1_CS PF18201.1 EST44433.1 - 1e-07 32.3 0.1 1.6e-07 31.7 0.1 1.3 1 0 0 1 1 1 1 PIH1 CS-like domain ArsA_HSP20 PF17886.1 EST44433.1 - 6.9e-06 25.5 0.1 1e-05 25.0 0.1 1.2 1 0 0 1 1 1 1 HSP20-like domain found in ArsA HSP20 PF00011.21 EST44433.1 - 0.0074 16.4 0.1 0.24 11.5 0.0 2.2 1 1 1 2 2 2 1 Hsp20/alpha crystallin family CS PF04969.16 EST44433.1 - 0.021 15.8 0.1 0.041 14.9 0.1 1.4 1 0 0 1 1 1 0 CS domain Glyco_hydro_65C PF03633.15 EST44433.1 - 0.035 14.0 0.1 4.9 7.2 0.0 3.0 2 1 1 3 3 3 0 Glycosyl hydrolase family 65, C-terminal domain KASH_CCD PF14662.6 EST44434.1 - 0.0039 17.0 3.1 0.0039 17.0 3.1 2.3 2 1 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH DUF4795 PF16043.5 EST44434.1 - 0.0054 16.4 21.4 0.041 13.5 12.5 2.7 2 1 0 2 2 2 2 Domain of unknown function (DUF4795) DUF1866 PF08952.11 EST44434.1 - 0.032 14.1 0.4 0.07 13.0 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) Mrx7 PF10906.8 EST44434.1 - 0.037 14.3 0.0 4.9 7.5 0.1 3.1 2 0 0 2 2 2 0 MIOREX complex component 7 CENP-L PF13092.6 EST44434.1 - 0.069 13.4 1.3 0.15 12.3 1.3 1.5 1 0 0 1 1 1 0 Kinetochore complex Sim4 subunit Fta1 PIN_8 PF18476.1 EST44434.1 - 3.7 7.3 15.3 0.17 11.8 8.0 2.0 2 0 0 2 2 2 0 PIN like domain Syntaxin-6_N PF09177.11 EST44434.1 - 7 7.3 14.1 17 6.1 10.0 3.2 2 1 0 2 2 2 0 Syntaxin 6, N-terminal TPR_1 PF00515.28 EST44435.1 - 0.0053 16.5 0.3 0.99 9.3 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EST44435.1 - 0.038 14.2 0.6 21 5.6 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Rad21_Rec8 PF04824.16 EST44435.1 - 0.098 12.0 1.5 0.42 9.9 0.1 2.5 2 0 0 2 2 2 0 Conserved region of Rad21 / Rec8 like protein Ldh_1_N PF00056.23 EST44436.1 - 1.6e-27 96.3 0.1 6.3e-27 94.4 0.0 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 EST44436.1 - 2.2e-24 86.2 0.0 3.1e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Mtr2 PF10429.9 EST44436.1 - 0.011 15.7 0.1 0.02 14.8 0.1 1.4 1 0 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 POR_N PF01855.19 EST44436.1 - 0.11 12.2 0.1 0.84 9.3 0.0 2.0 2 0 0 2 2 2 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Dockerin_1 PF00404.18 EST44437.1 - 0.00013 22.1 2.9 0.013 15.6 0.3 2.5 2 2 2 4 4 4 2 Dockerin type I domain EMA PF02488.15 EST44437.1 - 0.068 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Merozoite Antigen Myb_DNA-bind_6 PF13921.6 EST44439.1 - 0.0063 16.7 0.6 0.014 15.6 0.2 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF3452 PF11934.8 EST44439.1 - 0.0089 15.6 0.9 0.013 15.0 0.4 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF3452) DUF866 PF05907.13 EST44440.1 - 0.0048 16.8 1.1 0.0065 16.4 0.1 1.7 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF866) TPR_8 PF13181.6 EST44441.1 - 5.2e-06 26.3 0.0 0.77 10.1 0.0 5.2 5 2 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EST44441.1 - 8.2e-06 26.2 0.1 1.1 10.2 0.0 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EST44441.1 - 0.00076 19.9 0.8 0.7 10.4 0.0 4.1 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EST44441.1 - 0.0013 19.3 0.1 6.3 7.7 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EST44441.1 - 0.0014 18.9 0.2 1.2 9.4 0.0 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EST44441.1 - 0.0034 17.7 0.0 0.65 10.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EST44441.1 - 0.0083 16.1 0.2 1.2 9.3 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EST44441.1 - 0.02 14.7 0.1 0.63 10.0 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EST44441.1 - 0.027 14.6 0.0 4.7 7.6 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 EST44441.1 - 0.082 13.1 0.0 3.7 7.8 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EST44441.1 - 0.094 13.4 0.0 5.1 7.8 0.0 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat LRR_4 PF12799.7 EST44442.1 - 1 9.9 7.6 0.4 11.2 1.0 3.7 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) Peptidase_C1 PF00112.23 EST44443.1 - 3.4e-42 145.0 1.2 4e-42 144.8 1.2 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EST44443.1 - 0.0007 18.5 1.3 0.0012 17.7 1.3 1.3 1 0 0 1 1 1 1 Peptidase C1-like family Propeptide_C1 PF08127.13 EST44443.1 - 0.0018 18.1 0.2 0.0039 17.1 0.2 1.6 1 0 0 1 1 1 1 Peptidase family C1 propeptide GlcNAc-1_reg PF18440.1 EST44446.1 - 0.0034 17.6 1.0 0.26 11.5 0.0 2.3 1 1 1 2 2 2 2 Putative GlcNAc-1 phosphotransferase regulatory domain Thymidylate_kin PF02223.17 EST44447.1 - 2.1e-32 112.3 0.7 2.4e-32 112.1 0.7 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_18 PF13238.6 EST44447.1 - 0.00018 22.0 0.0 0.0003 21.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain dNK PF01712.19 EST44447.1 - 0.00038 20.4 1.7 0.073 12.9 1.7 2.2 1 1 0 1 1 1 1 Deoxynucleoside kinase AAA_14 PF13173.6 EST44447.1 - 0.0078 16.3 0.4 0.022 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EST44447.1 - 0.048 13.9 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RTBV_P12 PF06361.11 EST44447.1 - 0.17 12.3 0.5 0.71 10.3 0.2 2.0 2 0 0 2 2 2 0 Rice tungro bacilliform virus P12 protein Glyco_hydro_35 PF01301.19 EST44448.1 - 1.3e-07 31.5 0.0 1.2e-06 28.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 35 ATP-grasp_2 PF08442.10 EST44450.1 - 0.00091 18.8 0.1 0.0014 18.2 0.1 1.3 1 1 0 1 1 1 1 ATP-grasp domain GH97_C PF14509.6 EST44450.1 - 0.0026 17.9 0.3 0.11 12.7 0.0 2.1 2 0 0 2 2 2 1 Glycosyl-hydrolase 97 C-terminal, oligomerisation RRM_9 PF18444.1 EST44450.1 - 0.022 14.6 0.2 0.033 14.0 0.2 1.4 1 0 0 1 1 1 0 RNA recognition motif DUF3781 PF12636.7 EST44450.1 - 0.026 14.4 0.0 0.067 13.1 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3781) TctA PF01970.16 EST44450.1 - 0.29 9.8 0.1 0.34 9.6 0.1 1.0 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family DC_STAMP PF07782.13 EST44450.1 - 0.33 10.8 1.7 0.26 11.1 0.3 1.5 2 0 0 2 2 2 0 DC-STAMP-like protein DJ-1_PfpI PF01965.24 EST44452.1 - 3.9e-17 62.5 0.0 4.4e-17 62.4 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family MFS_1 PF07690.16 EST44454.1 - 2.2e-35 122.2 61.5 9.6e-32 110.3 38.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ArAE_1_C PF11728.8 EST44455.1 - 0.0038 17.2 0.1 0.0046 17.0 0.1 1.1 1 0 0 1 1 1 1 Putative aromatic acid exporter C-terminal domain NAD_kinase PF01513.21 EST44456.1 - 8.3e-45 153.2 0.0 1.2e-44 152.7 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 EST44456.1 - 0.05 13.2 0.0 0.092 12.4 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain zf-CHY PF05495.12 EST44457.1 - 1.3e-10 41.6 12.4 1.3e-10 41.6 12.4 4.0 1 1 2 3 3 3 2 CHY zinc finger zf-RING_5 PF14634.6 EST44457.1 - 1.4e-05 24.9 6.5 1.4e-05 24.9 6.5 5.7 5 2 0 5 5 5 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EST44457.1 - 2.9e-05 23.8 5.4 2.9e-05 23.8 5.4 5.9 2 1 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EST44457.1 - 0.0055 16.4 2.9 0.0055 16.4 2.9 3.5 4 0 0 4 4 4 1 RING-like zinc finger zf-RING_4 PF14570.6 EST44457.1 - 0.026 14.3 4.0 0.026 14.3 4.0 5.7 2 1 4 7 7 7 0 RING/Ubox like zinc-binding domain SWC7 PF17330.2 EST44459.1 - 0.044 13.8 4.0 0.095 12.8 2.2 1.9 1 1 1 2 2 2 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 Intein_splicing PF14890.6 EST44459.1 - 0.099 12.6 1.9 0.13 12.2 1.9 1.3 1 0 0 1 1 1 0 Intein splicing domain TcA_RBD PF18518.1 EST44460.1 - 0.0096 16.2 1.2 0.013 15.8 0.6 1.5 1 1 0 1 1 1 1 TcA receptor binding domain Brr6_like_C_C PF10104.9 EST44460.1 - 0.015 15.0 0.8 0.032 14.0 0.8 1.4 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain Pept_S41_N PF18294.1 EST44460.1 - 0.034 14.1 0.0 0.067 13.2 0.0 1.6 1 0 0 1 1 1 0 Peptidase S41 N-terminal domain SAE2 PF08573.10 EST44460.1 - 8.9 7.5 8.1 86 4.3 8.1 2.2 1 1 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus DUF3420 PF11900.8 EST44462.1 - 0.18 12.0 0.5 0.77 9.9 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3420) PCRF PF03462.18 EST44462.1 - 0.31 10.9 1.2 0.64 9.9 1.2 1.5 1 0 0 1 1 1 0 PCRF domain NAD_binding_8 PF13450.6 EST44463.1 - 0.28 11.4 1.9 0.53 10.6 1.9 1.4 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Sushi PF00084.20 EST44463.1 - 0.56 10.8 4.2 0.56 10.8 0.7 2.7 1 1 0 2 2 2 0 Sushi repeat (SCR repeat) SVWC PF15430.6 EST44463.1 - 0.62 10.4 9.3 9 6.7 1.1 3.4 2 1 1 3 3 3 0 Single domain von Willebrand factor type C VSP PF03302.13 EST44464.1 - 0.0005 19.0 0.1 0.0005 19.0 0.1 2.3 2 1 0 2 2 2 1 Giardia variant-specific surface protein DUF4366 PF14283.6 EST44464.1 - 0.027 14.5 0.0 0.033 14.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) PARM PF17061.5 EST44464.1 - 0.049 13.8 2.4 0.049 13.8 2.4 1.4 1 1 0 1 1 1 0 PARM CAP_N PF01213.19 EST44464.1 - 0.22 11.0 0.1 0.24 10.8 0.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Peptidase_M61 PF05299.12 EST44465.1 - 0.001 19.5 0.9 0.0041 17.5 0.2 1.9 1 1 0 2 2 2 1 M61 glycyl aminopeptidase DivIC PF04977.15 EST44465.1 - 0.01 15.6 7.1 0.13 12.0 1.0 2.3 2 0 0 2 2 2 0 Septum formation initiator BST2 PF16716.5 EST44465.1 - 0.32 11.6 7.3 0.36 11.4 1.5 2.4 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 SlyX PF04102.12 EST44465.1 - 1.1 9.9 6.4 14 6.4 0.5 2.5 1 1 0 2 2 2 0 SlyX LRR_9 PF14580.6 EST44466.1 - 6.3e-12 45.3 2.7 2.3e-08 33.7 0.5 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 EST44466.1 - 1.1e-11 44.7 9.0 2.3e-06 27.8 0.4 3.7 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EST44466.1 - 0.00012 21.7 8.7 0.068 13.0 1.1 3.0 2 1 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 EST44466.1 - 6 7.8 9.3 49 5.1 0.0 4.4 2 2 1 3 3 3 0 Leucine Rich Repeat SUR7 PF06687.12 EST44467.1 - 0.082 12.5 6.1 0.13 11.9 6.1 1.3 1 1 0 1 1 1 0 SUR7/PalI family RHD3 PF05879.12 EST44468.1 - 6.1e-47 160.2 26.5 2.3e-46 158.4 13.0 2.6 3 0 0 3 3 3 2 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.23 EST44468.1 - 2.8e-05 24.2 0.9 0.00019 21.5 0.0 2.8 3 1 0 3 3 3 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EST44468.1 - 0.00052 20.1 0.1 0.0021 18.2 0.0 2.1 2 0 0 2 2 2 1 Dynamin family FeoB_N PF02421.18 EST44468.1 - 0.013 15.0 0.0 0.057 13.0 0.0 2.1 1 0 0 1 1 1 0 Ferrous iron transport protein B RNA_helicase PF00910.22 EST44468.1 - 0.015 15.7 1.8 2.6 8.5 0.0 3.5 3 0 0 3 3 3 0 RNA helicase SRPRB PF09439.10 EST44468.1 - 0.016 14.6 3.0 0.02 14.3 0.0 2.6 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.6 EST44468.1 - 0.043 14.1 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain aGPT-Pplase2 PF18724.1 EST44468.1 - 0.052 13.3 0.5 0.15 11.8 0.2 2.0 2 0 0 2 2 2 0 Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 2 AAA_14 PF13173.6 EST44468.1 - 0.085 12.9 0.0 0.085 12.9 0.0 4.1 5 0 0 5 5 5 0 AAA domain RabGAP-TBC PF00566.18 EST44469.1 - 0.074 12.7 0.0 0.098 12.3 0.0 1.2 1 0 0 1 1 1 0 Rab-GTPase-TBC domain Peptidase_M20 PF01546.28 EST44470.1 - 2.6e-07 30.6 0.0 4e-07 30.0 0.0 1.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 AAA PF00004.29 EST44471.1 - 3.3e-30 105.2 0.0 5.7e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EST44471.1 - 1.6e-05 24.6 0.1 0.1 12.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 EST44471.1 - 5.3e-05 23.3 0.0 0.00011 22.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EST44471.1 - 0.00014 22.2 0.6 0.0017 18.6 0.5 2.5 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EST44471.1 - 0.00043 20.7 0.0 0.00071 20.0 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 EST44471.1 - 0.00056 19.9 1.5 0.068 13.1 0.1 2.6 2 1 1 3 3 3 1 Rad17 P-loop domain DnaB_C PF03796.15 EST44471.1 - 0.0012 18.2 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain TIP49 PF06068.13 EST44471.1 - 0.0013 18.1 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain ResIII PF04851.15 EST44471.1 - 0.0038 17.2 0.0 0.009 16.0 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit RuvB_N PF05496.12 EST44471.1 - 0.0093 15.7 0.0 0.022 14.5 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 EST44471.1 - 0.016 14.6 0.0 0.057 12.7 0.0 1.9 1 1 0 1 1 1 0 KaiC Mg_chelatase PF01078.21 EST44471.1 - 0.017 14.5 0.1 0.12 11.7 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 EST44471.1 - 0.017 14.4 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 EST44471.1 - 0.05 13.3 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Gtr1_RagA PF04670.12 EST44471.1 - 0.061 12.7 0.2 0.45 9.8 0.0 2.1 1 1 1 2 2 2 0 Gtr1/RagA G protein conserved region NACHT PF05729.12 EST44471.1 - 0.064 13.2 0.4 1.1 9.2 0.3 2.4 1 1 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 EST44471.1 - 0.065 13.2 0.5 0.43 10.6 0.5 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 EST44471.1 - 0.12 11.7 0.0 0.27 10.5 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_11 PF13086.6 EST44471.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EST44471.1 - 0.13 12.8 0.0 0.28 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain tRNA-synt_1 PF00133.22 EST44472.1 - 1.6e-206 687.2 0.0 2.4e-206 686.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EST44472.1 - 1.9e-23 83.1 0.1 4.1e-23 82.0 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EST44472.1 - 1.3e-14 53.7 0.4 2.8e-05 23.0 0.0 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EST44472.1 - 2.2e-05 24.0 0.1 5.2e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Myb_DNA-binding PF00249.31 EST44473.1 - 4.7e-06 26.7 0.1 9.2e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST44473.1 - 0.00033 20.8 0.4 0.00049 20.3 0.4 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain SnAPC_2_like PF11035.8 EST44473.1 - 0.0053 17.0 0.1 0.0062 16.7 0.1 1.1 1 0 0 1 1 1 1 Small nuclear RNA activating complex subunit 2, SNAP190 Myb SKICH PF17751.1 EST44473.1 - 0.06 13.9 0.1 0.078 13.5 0.1 1.3 1 1 0 1 1 1 0 SKICH domain Myb_DNA-bind_7 PF15963.5 EST44473.1 - 0.068 13.1 0.7 0.11 12.4 0.7 1.5 1 1 0 1 1 1 0 Myb DNA-binding like ABC_tran PF00005.27 EST44475.1 - 2.2e-24 86.6 0.1 4.2e-24 85.6 0.1 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EST44475.1 - 1e-12 47.9 19.4 1.6e-12 47.2 19.4 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 EST44475.1 - 1.5e-12 48.0 1.5 5.3e-09 36.3 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EST44475.1 - 3.4e-05 23.4 0.7 0.013 14.9 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain MeaB PF03308.16 EST44475.1 - 0.0013 17.7 0.1 0.0024 16.9 0.1 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 EST44475.1 - 0.0029 17.5 0.2 0.006 16.5 0.2 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 EST44475.1 - 0.015 15.0 0.1 0.033 13.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EST44475.1 - 0.074 12.2 0.1 0.62 9.2 0.1 2.1 1 1 0 1 1 1 0 NB-ARC domain MMR_HSR1 PF01926.23 EST44475.1 - 0.15 12.2 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 EST44475.1 - 0.18 11.5 0.2 0.58 9.9 0.2 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EST44475.1 - 0.2 12.1 1.9 0.32 11.5 0.1 2.0 1 1 1 2 2 2 0 AAA domain PARM PF17061.5 EST44477.1 - 0.098 12.8 0.7 0.15 12.1 0.7 1.2 1 0 0 1 1 1 0 PARM EGF_2 PF07974.13 EST44478.1 - 6e-10 39.3 233.4 0.0091 16.3 14.4 15.8 14 3 1 15 15 15 10 EGF-like domain Laminin_EGF PF00053.24 EST44478.1 - 7.8e-06 25.9 32.4 0.00029 20.9 11.7 14.2 9 3 4 13 13 13 4 Laminin EGF domain MLANA PF14991.6 EST44478.1 - 0.18 12.1 0.8 0.82 10.0 0.0 2.4 3 0 0 3 3 3 0 Protein melan-A EGF_2 PF07974.13 EST44479.1 - 0.00053 20.3 32.8 0.0013 19.1 10.4 4.9 4 3 2 6 6 6 3 EGF-like domain Laminin_EGF PF00053.24 EST44479.1 - 0.49 10.6 51.2 0.069 13.3 10.1 3.9 3 2 0 3 3 3 0 Laminin EGF domain GTP_EFTU PF00009.27 EST44480.1 - 4e-60 202.7 0.3 7e-60 201.9 0.1 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EST44480.1 - 5.1e-25 87.6 0.1 2.6e-23 82.1 0.0 2.5 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 EST44480.1 - 6.9e-19 67.7 0.0 1.7e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 EST44480.1 - 1.3e-15 57.2 0.0 3.1e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 EST44480.1 - 5.9e-12 45.8 0.1 1.5e-11 44.5 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EST44480.1 - 0.016 15.3 0.0 0.044 13.9 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.10 EST44480.1 - 0.1 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FOXO-TAD PF16676.5 EST44481.1 - 0.31 11.5 2.8 0.48 10.9 0.4 2.4 3 0 0 3 3 3 0 Transactivation domain of FOXO protein family Methyltr_RsmB-F PF01189.17 EST44484.1 - 6.9e-27 94.4 0.2 9.9e-27 93.9 0.2 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F RrnaAD PF00398.20 EST44484.1 - 4.2e-05 22.8 0.0 6.4e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EST44484.1 - 0.0044 17.7 0.1 0.044 14.5 0.0 2.2 1 1 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EST44484.1 - 0.005 16.5 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UpxZ PF06603.11 EST44484.1 - 0.017 15.4 0.2 0.87 9.9 0.0 2.5 2 0 0 2 2 2 0 UpxZ family of transcription anti-terminator antagonists Methyltransf_31 PF13847.6 EST44484.1 - 0.03 14.1 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 EST44484.1 - 0.034 13.2 0.0 0.054 12.6 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_15 PF09445.10 EST44484.1 - 0.047 13.3 0.0 0.097 12.2 0.0 1.7 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase FtsJ PF01728.19 EST44484.1 - 0.06 13.4 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Aminotran_5 PF00266.19 EST44485.1 - 9e-81 271.7 0.5 1.1e-80 271.4 0.5 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EST44485.1 - 1.3e-07 31.3 0.4 1.8e-07 30.7 0.4 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EST44485.1 - 2.1e-06 27.3 0.4 3.2e-06 26.7 0.4 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 EST44485.1 - 0.00057 18.7 0.1 0.00089 18.1 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain SHMT PF00464.19 EST44485.1 - 0.035 12.7 0.1 0.052 12.1 0.1 1.2 1 0 0 1 1 1 0 Serine hydroxymethyltransferase Metallophos PF00149.28 EST44486.1 - 2.7e-37 129.2 0.0 3.8e-37 128.8 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EST44486.1 - 0.0038 17.6 0.2 0.0092 16.4 0.2 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 EST44486.1 - 0.031 14.5 0.0 0.046 13.9 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Cytokin_check_N PF10407.9 EST44487.1 - 0.00075 19.4 0.4 0.0017 18.3 0.4 1.5 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus C_GCAxxG_C_C PF09719.10 EST44488.1 - 0.19 12.0 4.2 0.98 9.7 4.2 2.2 1 1 1 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) tRNA-synt_1b PF00579.25 EST44489.1 - 0.01 15.2 1.1 0.011 15.1 1.1 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) Ppx-GppA PF02541.16 EST44489.1 - 0.026 14.0 0.1 0.029 13.8 0.1 1.1 1 0 0 1 1 1 0 Ppx/GppA phosphatase family Rhodanese PF00581.20 EST44490.1 - 1.8e-14 54.1 0.0 4.1e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain LCAT PF02450.15 EST44491.1 - 7.7e-07 28.6 0.0 1.7e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abp2 PF09441.10 EST44491.1 - 0.058 13.5 0.6 12 5.9 0.3 2.3 2 0 0 2 2 2 0 ARS binding protein 2 SWIM PF04434.17 EST44492.1 - 0.00018 21.1 1.6 0.00022 20.8 0.6 1.6 2 0 0 2 2 2 1 SWIM zinc finger Sec-ASP3 PF15432.6 EST44492.1 - 0.083 13.0 0.5 0.14 12.3 0.5 1.3 1 0 0 1 1 1 0 Accessory Sec secretory system ASP3 SHIPPO-rpt PF07004.12 EST44493.1 - 7.4e-10 39.3 7.7 0.018 16.0 0.1 3.2 3 0 0 3 3 3 3 Sperm-tail PG-rich repeat tRNA-synt_1b PF00579.25 EST44494.1 - 0.027 13.8 0.1 0.047 13.0 0.1 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) Annexin PF00191.20 EST44496.1 - 0.001 19.1 6.6 0.22 11.6 0.3 3.1 3 0 0 3 3 3 2 Annexin HAD_2 PF13419.6 EST44496.1 - 0.0011 19.1 3.5 0.0025 17.9 0.8 2.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase 7tm_1 PF00001.21 EST44497.1 - 0.19 11.0 8.3 0.093 12.0 2.4 2.3 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) HAP2-GCS1 PF10699.9 EST44498.1 - 0.091 12.8 0.1 0.27 11.2 0.1 1.8 1 0 0 1 1 1 0 Male gamete fusion factor Cauli_VI PF01693.16 EST44499.1 - 0.091 13.1 2.7 0.9 9.9 0.3 2.3 2 0 0 2 2 2 0 Caulimovirus viroplasmin ThiI PF02568.14 EST44502.1 - 1.8e-05 24.4 0.0 3.4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.13 EST44502.1 - 0.0023 17.5 0.4 0.012 15.1 0.1 2.3 3 0 0 3 3 3 1 Queuosine biosynthesis protein QueC PSCyt3 PF07627.11 EST44502.1 - 0.068 13.5 0.0 0.68 10.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) Helicase_C PF00271.31 EST44506.1 - 1.2e-16 61.0 0.1 4.4e-16 59.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EST44506.1 - 7.6e-08 32.3 0.4 7.6e-08 32.3 0.4 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 EST44506.1 - 6.8e-07 29.6 0.0 1.6e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EST44506.1 - 8.4e-07 29.3 0.0 2.4e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) AAA_30 PF13604.6 EST44506.1 - 1.7e-05 24.7 0.1 2.8e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EST44506.1 - 0.00043 19.8 0.2 0.0053 16.2 0.2 2.4 1 1 0 1 1 1 1 PhoH-like protein AAA_22 PF13401.6 EST44506.1 - 0.00072 19.8 0.1 0.0022 18.3 0.1 1.8 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 EST44506.1 - 0.0027 17.6 0.0 0.0077 16.1 0.0 1.8 1 0 0 1 1 1 1 Helicase T2SSE PF00437.20 EST44506.1 - 0.028 13.5 0.0 0.07 12.2 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 EST44506.1 - 0.078 13.5 0.2 0.5 10.8 0.2 2.1 1 1 0 1 1 1 0 AAA domain TRAPP PF04051.16 EST44507.1 - 0.0062 16.3 0.1 0.015 15.1 0.1 1.6 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Ribosomal_L14e PF01929.17 EST44508.1 - 7.2e-11 42.4 0.8 9.8e-11 42.0 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 EST44508.1 - 0.0059 16.5 0.8 0.012 15.6 0.8 1.6 1 0 0 1 1 1 1 KOW motif Methyltransf_11 PF08241.12 EST44509.1 - 1.2e-15 57.9 0.0 1.8e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EST44509.1 - 3.4e-13 50.1 0.0 5.4e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EST44509.1 - 1.4e-12 47.7 0.4 2e-12 47.2 0.4 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EST44509.1 - 1.6e-07 31.3 0.0 1.9e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EST44509.1 - 5.3e-06 27.1 0.0 9.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 EST44509.1 - 4.7e-05 23.1 0.1 5.8e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 EST44509.1 - 8.2e-05 22.0 0.0 0.0001 21.7 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 EST44509.1 - 0.0001 22.0 0.5 0.00015 21.5 0.5 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.15 EST44509.1 - 0.00014 21.8 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase TehB PF03848.14 EST44509.1 - 0.0003 20.3 0.3 0.0004 19.8 0.3 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB PrmA PF06325.13 EST44509.1 - 0.00057 19.4 0.6 0.0015 18.0 0.6 1.7 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 EST44509.1 - 0.00083 19.4 0.1 0.0018 18.3 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 EST44509.1 - 0.003 16.7 0.0 0.0042 16.2 0.0 1.3 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.14 EST44509.1 - 0.0035 16.9 0.1 0.0067 16.0 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 EST44509.1 - 0.027 13.8 0.0 0.047 13.0 0.0 1.3 1 1 0 1 1 1 0 O-methyltransferase domain CRAL_TRIO PF00650.20 EST44509.1 - 0.065 13.0 0.7 0.086 12.6 0.3 1.4 2 0 0 2 2 2 0 CRAL/TRIO domain Fib_alpha PF08702.10 EST44510.1 - 0.0095 16.1 7.9 0.0095 16.1 7.9 4.0 1 1 2 4 4 4 1 Fibrinogen alpha/beta chain family bZIP_1 PF00170.21 EST44510.1 - 0.068 13.3 15.4 0.53 10.4 0.3 4.3 3 2 2 5 5 5 0 bZIP transcription factor HALZ PF02183.18 EST44510.1 - 0.24 11.6 14.3 1.2 9.4 0.6 4.8 3 2 1 4 4 4 0 Homeobox associated leucine zipper Mce4_CUP1 PF11887.8 EST44510.1 - 0.85 9.0 5.5 0.2 11.1 1.1 2.1 2 0 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative TSC22 PF01166.18 EST44510.1 - 2.7 8.4 12.0 6.7 7.1 0.5 4.4 3 1 2 5 5 5 0 TSC-22/dip/bun family TTL PF03133.15 EST44511.1 - 6.8e-57 192.8 0.6 6.8e-57 192.8 0.6 2.8 2 2 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EST44511.1 - 8.6e-07 28.5 0.0 0.004 16.4 0.0 3.0 2 1 0 2 2 2 2 YheC/D like ATP-grasp TTL PF03133.15 EST44512.1 - 8.6e-58 195.8 1.8 2.7e-57 194.2 1.8 1.7 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EST44512.1 - 4.6e-07 29.3 0.0 0.0022 17.3 0.0 2.7 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EST44512.1 - 0.069 12.4 0.0 2.7 7.2 0.0 2.3 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Dus PF01207.17 EST44513.1 - 6.5e-30 104.3 0.4 9.4e-30 103.8 0.0 1.4 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 EST44513.1 - 0.021 14.3 0.1 0.15 11.5 0.1 2.2 1 1 0 1 1 1 0 Histidine biosynthesis protein CAMP_factor PF07373.11 EST44513.1 - 0.057 13.0 4.9 3.6 7.1 0.1 3.1 3 0 0 3 3 3 0 CAMP factor (Cfa) WD40 PF00400.32 EST44516.1 - 1.2e-05 25.9 2.3 0.59 11.1 0.0 5.9 7 0 0 7 7 7 1 WD domain, G-beta repeat Utp13 PF08625.11 EST44516.1 - 0.0037 17.2 0.7 0.01 15.8 0.7 1.8 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain RNA_pol_Rpb2_4 PF04566.13 EST44516.1 - 0.038 14.3 0.5 0.3 11.4 0.0 2.8 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 4 Clathrin_H_link PF13838.6 EST44516.1 - 0.47 10.4 2.4 0.83 9.6 0.2 2.5 2 0 0 2 2 2 0 Clathrin-H-link Mesd PF10185.9 EST44516.1 - 0.49 10.3 3.6 0.21 11.5 0.2 2.3 3 0 0 3 3 3 0 Chaperone for wingless signalling and trafficking of LDL receptor Laminin_EGF PF00053.24 EST44517.1 - 5.8e-05 23.1 11.8 5.8e-05 23.1 11.8 7.9 4 2 3 7 7 7 1 Laminin EGF domain EGF_2 PF07974.13 EST44517.1 - 0.0018 18.6 11.0 0.0018 18.6 11.0 9.1 9 1 0 9 9 9 5 EGF-like domain EGF PF00008.27 EST44517.1 - 0.028 14.7 7.4 0.028 14.7 7.4 9.1 9 0 0 9 9 9 0 EGF-like domain Ldl_recept_a PF00057.18 EST44517.1 - 0.087 13.1 0.6 0.087 13.1 0.6 8.7 8 1 0 8 8 8 0 Low-density lipoprotein receptor domain class A DUF4083 PF13314.6 EST44517.1 - 0.097 12.6 0.4 0.15 12.1 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) CH PF00307.31 EST44518.1 - 4.9e-12 46.0 1.2 6.1e-08 32.8 0.1 3.1 2 0 0 2 2 2 2 Calponin homology (CH) domain Antigen_C PF16364.5 EST44518.1 - 0.03 14.7 0.3 0.11 12.8 0.0 2.1 2 0 0 2 2 2 0 Cell surface antigen C-terminus SF3a60_bindingd PF12108.8 EST44518.1 - 1.2 9.1 3.6 1.2 9.1 0.4 2.9 3 0 0 3 3 3 0 Splicing factor SF3a60 binding domain SLED PF12140.8 EST44518.1 - 5.9 7.4 7.3 39 4.8 0.1 4.4 4 1 0 4 4 4 0 SLED domain Peptidase_C10 PF01640.17 EST44518.1 - 6.3 7.1 7.3 4.2 7.6 1.9 2.5 3 0 0 3 3 3 0 Peptidase C10 family IFP_35_N PF07334.13 EST44519.1 - 0.038 14.1 9.1 0.23 11.5 2.9 3.1 2 1 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus FlaC_arch PF05377.11 EST44519.1 - 0.13 12.7 7.9 0.35 11.3 0.1 3.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) HALZ PF02183.18 EST44519.1 - 0.13 12.5 4.6 0.27 11.5 3.2 2.3 1 1 1 2 2 2 0 Homeobox associated leucine zipper bZIP_2 PF07716.15 EST44519.1 - 1.4 9.1 9.8 0.65 10.1 1.1 3.7 2 2 1 3 3 3 0 Basic region leucine zipper bZIP_1 PF00170.21 EST44519.1 - 1.9 8.6 8.6 0.37 10.9 3.3 2.6 2 0 0 2 2 2 0 bZIP transcription factor ZapB PF06005.12 EST44519.1 - 2.8 8.5 13.8 16 6.0 0.3 3.3 2 2 1 3 3 3 0 Cell division protein ZapB DUF1796 PF08795.10 EST44519.1 - 4.7 7.1 10.6 0.98 9.4 6.7 1.7 2 0 0 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) Spc7 PF08317.11 EST44520.1 - 0.00015 20.8 17.1 0.00033 19.6 17.1 1.6 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF4407 PF14362.6 EST44520.1 - 0.049 13.0 10.6 0.085 12.2 10.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FliJ PF02050.16 EST44520.1 - 0.05 13.8 21.8 0.025 14.8 18.7 2.2 2 1 0 2 2 2 0 Flagellar FliJ protein USP8_interact PF08941.10 EST44520.1 - 0.11 12.3 14.5 0.049 13.5 2.0 2.6 1 1 1 2 2 2 0 USP8 interacting ZYG-11_interact PF05884.12 EST44520.1 - 0.53 9.7 7.9 0.25 10.7 5.3 1.6 1 1 1 2 2 2 0 Interactor of ZYG-11 AI-2E_transport PF01594.16 EST44520.1 - 0.78 8.8 8.7 0.58 9.3 6.3 1.8 1 1 1 2 2 2 0 AI-2E family transporter DUF2258 PF10015.9 EST44520.1 - 1 9.5 5.4 0.87 9.8 1.6 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2258) DUF1548 PF07579.11 EST44520.1 - 2.5 8.5 16.0 0.15 12.4 7.4 3.0 2 1 2 4 4 4 0 Domain of Unknown Function (DUF1548) DUF1664 PF07889.12 EST44520.1 - 6.3 6.9 16.6 0.18 11.8 7.8 2.8 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) ApoO PF09769.9 EST44520.1 - 6.6 6.7 6.5 34 4.4 4.2 2.7 1 1 1 2 2 2 0 Apolipoprotein O DUF2203 PF09969.9 EST44520.1 - 7.7 7.3 8.8 2e+02 2.7 8.8 2.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Exonuc_VII_L PF02601.15 EST44520.1 - 8.3 5.9 20.1 14 5.1 20.1 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit TPR_2 PF07719.17 EST44521.1 - 3.8e-07 29.7 16.1 4.7e-05 23.2 0.1 5.4 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 EST44521.1 - 0.00015 22.4 0.5 0.15 12.7 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EST44521.1 - 0.00085 19.4 9.7 0.087 13.1 0.1 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EST44521.1 - 0.0011 19.6 0.9 0.21 12.5 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EST44521.1 - 0.0069 16.1 6.5 2.8 7.7 0.1 4.3 3 1 1 4 4 4 1 TPR repeat TPR_1 PF00515.28 EST44521.1 - 0.019 14.7 0.1 0.019 14.7 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 EST44521.1 - 0.023 15.0 10.9 1.3 9.3 0.1 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EST44521.1 - 0.023 15.3 2.2 9.6 7.1 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC5 PF12862.7 EST44521.1 - 0.035 14.2 1.7 6.1 7.0 1.0 3.2 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 5 Toxin_10 PF05431.11 EST44521.1 - 0.18 11.3 2.2 7.3 6.0 0.4 2.6 3 0 0 3 3 3 0 Insecticidal Crystal Toxin, P42 TPR_MalT PF17874.1 EST44521.1 - 1.3 8.3 10.2 4.4 6.6 3.5 3.0 2 1 0 3 3 3 0 MalT-like TPR region ANAPC3 PF12895.7 EST44521.1 - 2.2 8.6 19.8 0.86 9.9 1.1 4.1 2 2 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EST44521.1 - 8.4 7.0 9.8 6.9 7.3 0.1 3.9 4 1 1 5 5 5 0 Tetratricopeptide repeat NYD-SP28_assoc PF14775.6 EST44523.1 - 1e-15 57.6 1.9 1e-15 57.6 1.9 4.8 4 1 1 5 5 5 1 Sperm tail C-terminal domain NYD-SP28 PF14772.6 EST44523.1 - 1.9e-07 31.1 1.9 1.9e-07 31.1 1.9 5.5 4 1 1 5 5 5 1 Sperm tail MinE PF03776.14 EST44523.1 - 3.6 7.7 7.1 1.1 9.4 0.2 3.6 5 0 0 5 5 5 0 Septum formation topological specificity factor MinE Occludin_ELL PF07303.13 EST44524.1 - 0.00092 19.9 5.9 0.00092 19.9 5.9 1.8 1 1 1 2 2 2 1 Occludin homology domain DUF4407 PF14362.6 EST44524.1 - 0.028 13.8 4.2 0.036 13.4 4.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sipho_Gp157 PF05565.11 EST44524.1 - 0.038 14.0 0.9 0.047 13.7 0.9 1.1 1 0 0 1 1 1 0 Siphovirus Gp157 bZIP_1 PF00170.21 EST44525.1 - 0.013 15.6 2.0 0.013 15.6 2.0 3.7 3 1 1 4 4 4 0 bZIP transcription factor HATPase_c_4 PF13749.6 EST44525.1 - 0.077 13.1 0.1 0.24 11.6 0.1 1.9 1 0 0 1 1 1 0 Putative ATP-dependent DNA helicase recG C-terminal TSNAXIP1_N PF15739.5 EST44525.1 - 6.3 7.2 19.2 4.4 7.7 3.0 3.2 1 1 2 3 3 3 0 Translin-associated factor X-interacting N-terminus VSP PF03302.13 EST44527.1 - 0.026 13.4 70.5 0.021 13.7 37.3 2.4 1 1 1 2 2 2 0 Giardia variant-specific surface protein FTR1 PF03239.14 EST44527.1 - 0.17 11.0 0.9 0.25 10.5 0.9 1.1 1 0 0 1 1 1 0 Iron permease FTR1 family VSP PF03302.13 EST44528.1 - 1.8e-06 27.1 86.3 2e-06 26.9 49.1 2.4 1 1 1 2 2 2 2 Giardia variant-specific surface protein DUF4690 PF15756.5 EST44528.1 - 0.013 16.1 0.1 0.024 15.2 0.1 1.6 1 0 0 1 1 1 0 Small Novel Rich in Cartilage DUF4366 PF14283.6 EST44528.1 - 0.97 9.5 3.9 4.8 7.2 3.9 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Podoplanin PF05808.11 EST44529.1 - 0.33 11.1 1.5 0.61 10.2 1.5 1.4 1 0 0 1 1 1 0 Podoplanin Hit1_C PF18268.1 EST44530.1 - 0.014 15.6 0.3 0.014 15.6 0.3 2.1 2 1 0 2 2 2 0 Hit1 C-terminal NEMO PF11577.8 EST44530.1 - 0.029 14.4 0.2 0.029 14.4 0.2 3.4 3 1 0 3 3 3 0 NF-kappa-B essential modulator NEMO Androgen_recep PF02166.16 EST44530.1 - 3.6 6.3 7.6 5.6 5.7 7.6 1.3 1 0 0 1 1 1 0 Androgen receptor YabA PF06156.13 EST44530.1 - 6.8 7.4 16.2 1.3 9.7 10.9 2.4 1 1 1 2 2 2 0 Initiation control protein YabA Na_H_Exchanger PF00999.21 EST44531.1 - 5.8e-61 206.4 42.7 7.5e-61 206.0 42.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Helicase_C PF00271.31 EST44533.1 - 2.5e-13 50.3 0.2 2.5e-13 50.3 0.2 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 EST44533.1 - 5.2e-09 36.1 2.4 4.1e-08 33.2 0.2 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 EST44533.1 - 4.2e-05 23.8 0.0 0.00016 22.0 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_19 PF13245.6 EST44533.1 - 0.0021 18.4 0.0 0.0045 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EST44533.1 - 0.011 14.9 0.1 0.24 10.4 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_22 PF13401.6 EST44533.1 - 0.02 15.2 0.1 0.094 13.0 0.1 2.1 1 1 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 EST44533.1 - 0.037 13.9 0.0 0.098 12.5 0.0 1.8 1 0 0 1 1 1 0 Helicase HA2 PF04408.23 EST44533.1 - 0.11 12.7 0.0 0.4 11.0 0.0 1.9 2 0 0 2 2 2 0 Helicase associated domain (HA2) Peptidase_M20 PF01546.28 EST44534.1 - 3.4e-07 30.2 0.0 7.2e-07 29.1 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 EST44534.1 - 3.4e-05 23.0 0.0 0.0018 17.3 0.1 2.7 2 1 0 3 3 3 1 M42 glutamyl aminopeptidase M20_dimer PF07687.14 EST44534.1 - 0.0055 16.6 0.1 0.02 14.8 0.1 2.1 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF1938 PF09153.10 EST44534.1 - 0.051 13.7 0.1 0.13 12.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1938) Peptidase_M28 PF04389.17 EST44534.1 - 0.063 13.0 0.1 2.2 7.9 0.0 2.4 2 0 0 2 2 2 0 Peptidase family M28 MscL PF01741.18 EST44535.1 - 0.071 13.4 1.6 0.11 12.8 1.5 1.5 1 1 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL Acyltransferase PF01553.21 EST44536.1 - 1.6e-10 40.8 0.0 2.8e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Thioredoxin PF00085.20 EST44537.1 - 0.067 13.2 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin Aldedh PF00171.22 EST44537.1 - 0.15 10.6 0.0 0.21 10.0 0.0 1.1 1 0 0 1 1 1 0 Aldehyde dehydrogenase family DAP_B PF07930.12 EST44538.1 - 0.022 14.8 0.3 0.049 13.6 0.3 1.5 1 0 0 1 1 1 0 D-aminopeptidase, domain B LisH_TPL PF17814.1 EST44538.1 - 1.1 8.9 5.5 5.3 6.8 0.0 3.4 3 0 0 3 3 3 0 LisH-like dimerisation domain DivIC PF04977.15 EST44538.1 - 1.2 8.9 17.8 2.9 7.7 0.2 4.0 4 0 0 4 4 4 0 Septum formation initiator LMBR1 PF04791.16 EST44538.1 - 1.3 7.9 7.8 2 7.2 7.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein LprI PF07007.12 EST44538.1 - 5 7.8 7.7 15 6.3 0.5 2.9 1 1 1 2 2 2 0 Lysozyme inhibitor LprI DUF4690 PF15756.5 EST44539.1 - 0.0089 16.6 2.0 0.016 15.8 2.0 1.4 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Podoplanin PF05808.11 EST44539.1 - 0.023 14.8 1.7 0.038 14.1 1.7 1.2 1 0 0 1 1 1 0 Podoplanin PTP_tm PF18861.1 EST44539.1 - 0.053 13.5 0.4 0.099 12.6 0.4 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J LapA_dom PF06305.11 EST44539.1 - 0.12 12.2 0.4 0.19 11.6 0.4 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain ALS_ss_C PF10369.9 EST44540.1 - 0.0074 16.5 0.1 0.68 10.2 0.0 2.7 2 0 0 2 2 2 2 Small subunit of acetolactate synthase KASH_CCD PF14662.6 EST44541.1 - 4.5e-06 26.6 8.3 5.4e-06 26.4 8.3 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH SKA1 PF07160.12 EST44541.1 - 0.0079 16.1 7.4 0.0091 15.9 7.4 1.0 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 STAT_alpha PF01017.20 EST44541.1 - 0.023 14.6 7.8 0.034 14.0 7.8 1.5 1 1 0 1 1 1 0 STAT protein, all-alpha domain CCDC24 PF15669.5 EST44541.1 - 0.33 10.8 9.8 1.5 8.7 2.2 2.2 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 24 family YabA PF06156.13 EST44541.1 - 0.93 10.2 6.7 2.1 9.0 6.7 1.8 1 1 0 1 1 1 0 Initiation control protein YabA DSPn PF14671.6 EST44543.1 - 7e-18 65.4 2.0 5.2e-15 56.1 0.8 2.6 2 1 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EST44543.1 - 5.5e-08 32.7 1.6 9.1e-08 32.0 0.3 2.1 2 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Band_3_cyto PF07565.13 EST44545.1 - 2.6 7.8 15.1 3.6 7.3 13.8 1.8 1 1 0 1 1 1 0 Band 3 cytoplasmic domain RinB PF06116.12 EST44546.1 - 0.12 12.5 0.5 13 5.9 0.0 3.4 3 0 0 3 3 3 0 Transcriptional activator RinB Glypican PF01153.19 EST44547.1 - 0.18 10.6 0.0 0.18 10.6 0.0 1.0 1 0 0 1 1 1 0 Glypican Fe-ADH PF00465.19 EST44548.1 - 5.3e-53 180.1 0.0 6.6e-53 179.8 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EST44548.1 - 1.3e-10 41.4 0.0 6e-08 32.7 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Bac_export_2 PF01312.19 EST44549.1 - 2 7.5 4.1 2.5 7.2 4.1 1.1 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family PRRSV_2b PF07069.11 EST44549.1 - 4.3 7.9 9.8 0.89 10.1 1.6 2.2 1 1 1 2 2 2 0 Porcine reproductive and respiratory syndrome virus 2b UPF0697 PF15117.6 EST44550.1 - 0.0052 16.8 0.4 0.011 15.7 0.4 1.5 1 0 0 1 1 1 1 Uncharacterised protein family UPF0697 DUF3754 PF12576.8 EST44550.1 - 0.015 15.3 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3754) NPL PF17800.1 EST44550.1 - 0.076 13.6 0.4 0.11 13.1 0.4 1.4 1 1 0 1 1 1 0 Nucleoplasmin-like domain Pkinase PF00069.25 EST44551.1 - 2.2e-53 181.3 0.0 2.7e-53 181.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST44551.1 - 2.4e-21 76.2 0.0 3.5e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EST44551.1 - 0.0018 17.9 0.1 0.0041 16.7 0.1 1.7 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 EST44551.1 - 0.0036 17.3 0.0 0.0094 15.9 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EST44551.1 - 0.0079 15.8 0.1 0.015 14.9 0.1 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase SHIPPO-rpt PF07004.12 EST44553.1 - 4.9e-13 49.3 21.4 0.00026 21.8 0.8 6.4 6 0 0 6 6 6 6 Sperm-tail PG-rich repeat Acetyltransf_16 PF05301.11 EST44554.1 - 7.2e-14 51.9 0.3 7.2e-14 51.9 0.3 2.1 2 0 0 2 2 2 1 GNAT acetyltransferase, Mec-17 PilN PF05137.13 EST44555.1 - 0.08 13.1 0.3 0.093 12.9 0.3 1.2 1 0 0 1 1 1 0 Fimbrial assembly protein (PilN) Prenyltrans PF00432.21 EST44556.1 - 1e-18 66.7 1.7 3.5e-06 26.6 0.0 4.6 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat ERCC3_RAD25_C PF16203.5 EST44557.1 - 0.0056 15.9 0.0 0.0057 15.9 0.0 1.0 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Baculo_p74 PF04583.12 EST44557.1 - 0.065 12.7 0.1 0.073 12.5 0.1 1.1 1 0 0 1 1 1 0 Baculoviridae p74 conserved region KH_8 PF17903.1 EST44558.1 - 1.4e-12 47.5 0.0 2.7e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain DUF3304 PF11745.8 EST44558.1 - 0.064 13.7 0.2 0.11 13.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3304) Ribosomal_L19e PF01280.20 EST44559.1 - 9.7e-50 168.4 6.2 1.7e-49 167.6 6.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L19e SHIPPO-rpt PF07004.12 EST44561.1 - 0.0045 17.9 16.1 15 6.7 0.0 5.8 5 1 0 5 5 5 3 Sperm-tail PG-rich repeat Nop10p PF04135.12 EST44561.1 - 0.53 10.4 5.8 18 5.5 0.1 3.1 2 1 0 2 2 2 0 Nucleolar RNA-binding protein, Nop10p family SHIPPO-rpt PF07004.12 EST44562.1 - 7.9e-15 55.0 34.2 0.18 12.8 0.0 10.8 11 0 0 11 11 11 8 Sperm-tail PG-rich repeat DUF5406 PF17400.2 EST44563.1 - 0.073 13.5 0.3 0.098 13.1 0.3 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5406) U1snRNP70_N PF12220.8 EST44563.1 - 0.37 11.4 8.0 0.87 10.3 4.0 2.0 1 1 1 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal N_formyltrans_C PF18216.1 EST44564.1 - 0.0041 16.8 0.0 0.013 15.2 0.0 1.8 1 0 0 1 1 1 1 N-formyltransferase dimerization C-terminal domain tRNA_int_endo PF01974.17 EST44565.1 - 3.2e-12 46.3 0.1 5.5e-12 45.6 0.1 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Baculo_IE-1 PF05290.11 EST44565.1 - 0.065 13.2 0.9 0.11 12.5 0.9 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) PA28_beta PF02252.18 EST44566.1 - 9.8e-10 38.3 0.1 2.7e-09 36.8 0.0 1.7 2 0 0 2 2 2 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.18 EST44566.1 - 0.0078 16.2 1.5 0.026 14.6 0.2 2.5 1 1 2 3 3 3 1 Proteasome activator pa28 alpha subunit TMEM131_like PF12371.8 EST44567.1 - 0.065 13.5 4.4 6.2 7.2 0.3 2.7 2 0 0 2 2 2 0 Transmembrane protein 131-like SNAP PF14938.6 EST44568.1 - 5.7e-53 180.2 18.5 6.3e-53 180.0 18.5 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_2 PF07719.17 EST44568.1 - 3.6e-05 23.5 10.3 0.021 14.9 0.1 4.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EST44568.1 - 0.00013 22.2 6.5 0.027 14.8 0.3 3.4 2 1 0 3 3 3 2 Tetratricopeptide repeat MIT PF04212.18 EST44568.1 - 0.0036 17.3 2.3 0.0036 17.3 2.3 4.3 3 1 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 EST44568.1 - 0.0042 16.7 7.2 0.16 11.7 0.1 4.2 4 2 0 4 4 4 1 TPR repeat NSF PF02071.20 EST44568.1 - 0.0053 17.2 16.0 0.12 13.1 0.1 6.4 6 1 1 7 7 6 1 Aromatic-di-Alanine (AdAR) repeat TPR_8 PF13181.6 EST44568.1 - 0.0057 16.8 7.9 3.7 8.0 0.1 4.8 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 EST44568.1 - 0.0066 16.2 13.7 0.055 13.3 0.1 4.5 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EST44568.1 - 0.0074 16.2 3.7 2.9 8.1 0.2 4.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EST44568.1 - 0.013 16.3 3.6 2.6 9.1 0.2 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 EST44568.1 - 3.2 8.5 7.0 0.75 10.5 0.2 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat CDP-OH_P_transf PF01066.21 EST44569.1 - 9.9e-14 51.9 0.5 9.9e-14 51.9 0.5 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Ost5 PF05251.12 EST44570.1 - 0.0029 17.8 2.5 0.0044 17.2 2.5 1.2 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 DUF3810 PF12725.7 EST44570.1 - 0.032 13.6 1.1 0.035 13.4 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) WD40 PF00400.32 EST44572.1 - 2.4e-06 28.1 1.7 2.7 9.0 0.3 5.8 5 1 1 6 6 6 2 WD domain, G-beta repeat EF-1_beta_acid PF10587.9 EST44572.1 - 0.0054 17.1 0.5 0.011 16.2 0.5 1.5 1 0 0 1 1 1 1 Eukaryotic elongation factor 1 beta central acidic region Cu-oxidase_4 PF02578.15 EST44572.1 - 0.061 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Multi-copper polyphenol oxidoreductase laccase Topoisom_bac PF01131.20 EST44573.1 - 1.8e-68 231.5 3.1 2.6e-68 231.0 3.1 1.2 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 EST44573.1 - 2.3e-13 50.2 0.1 2.2e-12 47.1 0.0 2.4 2 0 0 2 2 2 1 Toprim domain Toprim_2 PF13155.6 EST44573.1 - 0.014 15.8 0.0 0.04 14.3 0.0 1.7 1 0 0 1 1 1 0 Toprim-like Toprim_4 PF13662.6 EST44573.1 - 0.015 15.7 0.0 0.041 14.4 0.0 1.7 1 0 0 1 1 1 0 Toprim domain HTH_45 PF14947.6 EST44573.1 - 0.064 13.2 0.3 0.31 11.0 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix HTH_40 PF14493.6 EST44573.1 - 1 9.9 4.3 1.4e+02 3.0 0.0 4.0 4 0 0 4 4 4 0 Helix-turn-helix domain COX7B PF05392.11 EST44574.1 - 0.027 14.2 0.0 0.066 12.9 0.0 1.8 1 0 0 1 1 1 0 Cytochrome C oxidase chain VIIB Toxin_15 PF07906.13 EST44574.1 - 0.17 11.4 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 ShET2 enterotoxin, N-terminal region Phage_holin_3_3 PF16083.5 EST44574.1 - 2.2 8.4 13.3 7.3 6.8 6.5 3.3 1 1 1 3 3 3 0 LydA holin phage, holin superfamily III DUF1072 PF06380.11 EST44574.1 - 5.4 7.0 7.8 2.2 8.2 2.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) FATC PF02260.20 EST44576.1 - 1.4 8.8 5.4 4.3 7.2 0.1 2.5 2 0 0 2 2 2 0 FATC domain 7tm_1 PF00001.21 EST44577.1 - 0.026 13.9 2.8 0.033 13.5 2.8 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Myb_DNA-bind_6 PF13921.6 EST44578.1 - 2.9e-06 27.4 7.7 9e-06 25.8 7.7 1.9 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EST44578.1 - 0.0034 17.6 10.8 0.035 14.3 2.0 3.3 2 1 0 2 2 2 2 Myb-like DNA-binding domain DUF3627 PF12299.8 EST44578.1 - 0.045 13.8 0.0 0.095 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3627) PGM_PMM_II PF02879.16 EST44579.1 - 0.0017 18.9 0.0 0.14 12.8 0.0 2.2 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Imm6 PF14434.6 EST44580.1 - 0.15 12.0 2.3 1.1 9.2 0.2 2.2 2 0 0 2 2 2 0 Immunity protein Imm6 SBF2 PF12335.8 EST44581.1 - 0.018 14.7 0.3 0.031 13.9 0.3 1.4 1 0 0 1 1 1 0 Myotubularin protein ADIP PF11559.8 EST44581.1 - 0.37 10.9 9.9 2.9 8.0 3.6 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding ERM PF00769.19 EST44581.1 - 0.5 10.2 6.6 1.1 9.0 0.3 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Polysacc_syn_2C PF08485.10 EST44581.1 - 1.9 8.3 4.8 3.7 7.3 0.2 2.9 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein C-terminal bZIP_2 PF07716.15 EST44581.1 - 6.5 6.9 8.7 17 5.5 2.9 2.8 3 0 0 3 3 3 0 Basic region leucine zipper LRR_9 PF14580.6 EST44582.1 - 3.8e-12 46.1 0.8 8.1e-12 45.0 0.8 1.6 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EST44582.1 - 2.3e-11 43.7 4.4 5.3e-06 26.7 0.2 3.9 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EST44582.1 - 3.9e-05 23.3 2.1 0.00049 19.8 0.5 2.8 2 1 0 2 2 2 1 Leucine rich repeat LRR_6 PF13516.6 EST44582.1 - 0.12 12.5 0.2 0.12 12.5 0.2 3.1 4 0 0 4 4 4 0 Leucine Rich repeat TFIIA PF03153.13 EST44582.1 - 0.15 12.0 16.3 0.17 11.9 16.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Endostatin PF06482.11 EST44582.1 - 0.26 10.7 4.6 0.36 10.2 4.6 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Suf PF05843.14 EST44582.1 - 3.1 7.7 11.4 4.9 7.0 11.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF2076 PF09849.9 EST44582.1 - 4.8 7.1 19.5 10 6.1 19.5 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) AMP-binding PF00501.28 EST44585.1 - 6.2e-08 31.7 0.0 1e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Peptidase_C1 PF00112.23 EST44586.1 - 6e-36 124.6 0.9 1.3e-35 123.5 0.9 1.6 1 1 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EST44586.1 - 0.00015 20.7 2.0 0.0032 16.3 0.2 2.4 2 1 0 2 2 2 2 Peptidase C1-like family TPPK_C PF12555.8 EST44586.1 - 0.093 12.8 0.2 0.17 11.9 0.2 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal DUF5423 PF17461.2 EST44587.1 - 1.1 8.0 4.9 0.22 10.3 1.6 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5423) DHC_N2 PF08393.13 EST44588.1 - 5e-120 401.3 17.7 5e-120 401.3 17.7 5.2 4 1 1 5 5 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 EST44588.1 - 4.4e-94 315.1 7.9 5.4e-91 305.0 7.9 4.0 1 1 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region Dynein_C PF18199.1 EST44588.1 - 5.4e-83 278.7 1.6 1.6e-81 273.9 0.0 3.8 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 EST44588.1 - 3.3e-78 262.6 0.3 3.3e-78 262.6 0.3 2.5 3 0 0 3 3 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 EST44588.1 - 5e-69 231.8 4.6 5e-69 231.8 4.6 4.3 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 EST44588.1 - 1.7e-60 203.6 1.6 8.6e-59 198.1 0.0 3.4 3 0 0 3 3 2 1 P-loop containing dynein motor region MT PF12777.7 EST44588.1 - 1.8e-51 175.2 11.2 4e-51 174.1 11.2 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 EST44588.1 - 4.2e-35 121.0 0.0 2.5e-34 118.5 0.0 2.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EST44588.1 - 3.3e-33 114.3 0.2 7.2e-32 110.0 0.1 3.4 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 EST44588.1 - 5.3e-19 68.6 0.6 5.3e-19 68.6 0.6 3.4 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 EST44588.1 - 1.3e-12 47.8 0.0 8.3e-12 45.2 0.0 2.6 1 1 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EST44588.1 - 1.3e-09 38.1 0.0 0.52 10.3 0.0 5.8 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EST44588.1 - 2.4e-06 27.9 3.0 0.03 14.6 0.0 5.3 4 1 0 4 4 3 1 AAA domain T2SSE PF00437.20 EST44588.1 - 0.00041 19.5 6.9 0.001 18.2 0.2 4.3 5 0 0 5 5 5 1 Type II/IV secretion system protein AAA_16 PF13191.6 EST44588.1 - 0.012 16.0 4.2 2.6 8.4 0.0 5.2 5 0 0 5 5 4 0 AAA ATPase domain AAA_30 PF13604.6 EST44588.1 - 0.028 14.2 0.2 2.3 7.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EST44588.1 - 0.052 12.9 0.1 14 5.0 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.6 EST44588.1 - 0.27 11.4 2.1 15 5.7 0.0 3.7 3 0 0 3 3 3 0 AAA domain DUF3452 PF11934.8 EST44588.1 - 1.6 8.3 7.3 0.95 9.0 0.6 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF3452) CCDC32 PF14989.6 EST44588.1 - 6.6 6.7 13.6 0.36 10.8 6.1 2.6 2 0 0 2 2 2 0 Coiled-coil domain containing 32 LPD29 PF18847.1 EST44589.1 - 0.085 13.8 0.0 0.31 12.0 0.0 1.9 2 0 0 2 2 2 0 Large polyvalent protein associated domain 29 Prenyltrans PF00432.21 EST44590.1 - 5.2e-19 67.7 9.4 8.7e-08 31.8 0.0 4.6 5 0 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat DUF4925 PF16272.5 EST44590.1 - 0.028 13.9 0.5 0.043 13.3 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4925) DUF2315 PF10231.9 EST44590.1 - 0.44 10.7 2.2 0.64 10.1 2.2 1.2 1 0 0 1 1 1 0 Apoptogenic protein 1 UQ_con PF00179.26 EST44591.1 - 3.8e-35 120.6 0.1 4.8e-35 120.3 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EST44591.1 - 0.004 16.8 0.0 0.0054 16.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B SHIPPO-rpt PF07004.12 EST44592.1 - 0.00013 22.7 18.6 0.031 15.2 7.1 4.5 4 1 0 4 4 4 2 Sperm-tail PG-rich repeat RRM_3 PF08777.11 EST44595.1 - 2.2e-09 37.2 0.1 4.8e-09 36.2 0.1 1.5 1 0 0 1 1 1 1 RNA binding motif DUF5105 PF17118.5 EST44596.1 - 0.00079 19.3 2.0 0.00079 19.3 2.0 1.8 2 1 0 2 2 2 1 Domain of unknown function (DUF5105) Macoilin PF09726.9 EST44596.1 - 0.0029 16.3 9.8 0.0035 16.0 3.9 2.0 2 0 0 2 2 2 2 Macoilin family K-box PF01486.17 EST44596.1 - 0.012 15.8 4.2 0.028 14.6 4.2 1.7 1 0 0 1 1 1 0 K-box region DUF1664 PF07889.12 EST44596.1 - 0.036 14.1 1.5 0.036 14.1 1.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 EST44596.1 - 0.061 13.8 8.1 0.14 12.6 8.0 1.8 1 1 0 1 1 1 0 Fez1 BRE1 PF08647.11 EST44596.1 - 0.16 12.1 10.0 0.056 13.5 6.5 2.1 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DivIC PF04977.15 EST44596.1 - 0.35 10.7 8.5 0.19 11.5 5.1 2.2 1 1 1 2 2 2 0 Septum formation initiator Spc24 PF08286.11 EST44596.1 - 0.38 11.0 7.5 0.73 10.1 7.5 1.8 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 GrpE PF01025.19 EST44596.1 - 3.2 7.4 11.0 6.4 6.4 11.0 1.5 1 1 0 1 1 1 0 GrpE Adap_comp_sub PF00928.21 EST44597.1 - 8.2e-58 195.8 1.9 1.1e-57 195.5 1.9 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family ADK PF00406.22 EST44598.1 - 5.5e-29 101.2 0.0 6.8e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EST44598.1 - 8.4e-21 74.8 0.1 1.4e-20 74.1 0.0 1.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EST44598.1 - 2.1e-09 38.0 0.0 6.9e-09 36.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EST44598.1 - 5.9e-06 26.5 0.2 0.00067 19.8 0.2 2.2 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EST44598.1 - 1e-05 25.3 0.2 2.3e-05 24.2 0.1 1.6 2 0 0 2 2 2 1 Thymidylate kinase Sigma54_activ_2 PF14532.6 EST44598.1 - 0.023 14.8 0.0 0.1 12.7 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain dNK PF01712.19 EST44598.1 - 0.031 14.1 0.2 0.22 11.4 0.1 2.0 1 1 1 2 2 2 0 Deoxynucleoside kinase APS_kinase PF01583.20 EST44598.1 - 0.091 12.7 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Zeta_toxin PF06414.12 EST44598.1 - 0.11 11.8 0.1 3.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin Mto2_bdg PF12808.7 EST44599.1 - 1.4 9.3 8.1 0.27 11.6 1.6 2.9 4 0 0 4 4 4 0 Micro-tubular organiser Mto1 C-term Mto2-binding region NYD-SP28_assoc PF14775.6 EST44599.1 - 2.9 8.1 6.9 28 4.9 2.5 2.8 2 0 0 2 2 2 0 Sperm tail C-terminal domain T7SS_ESX_EspC PF10824.8 EST44600.1 - 1.9 9.0 18.0 2.5 8.6 2.8 3.7 3 0 0 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm SHIPPO-rpt PF07004.12 EST44602.1 - 1.5e-09 38.3 27.2 0.06 14.3 0.5 6.4 5 1 0 6 6 6 5 Sperm-tail PG-rich repeat DnaI_N PF07319.11 EST44603.1 - 8 7.2 11.7 16 6.2 0.4 3.6 2 1 1 3 3 3 0 Primosomal protein DnaI N-terminus DUF533 PF04391.12 EST44604.1 - 0.19 11.3 1.9 18 4.9 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF533) TSP_NTD PF17804.1 EST44605.1 - 0.37 11.0 15.3 0.84 9.9 15.3 1.7 1 1 0 1 1 1 0 Tail specific protease N-terminal domain DUF1635 PF07795.11 EST44605.1 - 1.8 8.4 11.7 2.2 8.1 10.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1635) YusW PF14039.6 EST44606.1 - 0.0028 18.1 6.1 0.53 10.8 0.2 3.6 2 1 1 3 3 3 2 YusW-like protein ATP-synt_E_2 PF08112.11 EST44606.1 - 0.02 15.1 0.2 0.02 15.1 0.2 2.7 3 1 1 4 4 4 0 ATP synthase epsilon subunit Cep57_CLD_2 PF14197.6 EST44606.1 - 0.063 13.4 1.1 0.19 11.8 1.1 1.9 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 HALZ PF02183.18 EST44606.1 - 0.17 12.1 1.7 1.4 9.2 0.6 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper FapA PF03961.13 EST44606.1 - 0.36 9.4 4.2 0.44 9.1 3.4 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A zf-CHY PF05495.12 EST44607.1 - 1.3e-07 32.0 25.0 1.3e-07 32.0 25.0 2.5 2 0 0 2 2 2 1 CHY zinc finger PP2C PF00481.21 EST44610.1 - 4.7e-43 147.7 0.0 1.4e-28 100.2 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C Clathrin PF00637.20 EST44610.1 - 0.0092 15.9 0.5 0.031 14.1 0.5 2.0 1 0 0 1 1 1 1 Region in Clathrin and VPS LRR_6 PF13516.6 EST44610.1 - 0.042 13.9 0.2 2 8.7 0.0 3.1 3 0 0 3 3 3 0 Leucine Rich repeat YnfE PF17452.2 EST44610.1 - 0.18 12.1 0.7 0.5 10.7 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized YnfE-like DUF4606 PF15379.6 EST44611.1 - 0.0022 18.2 9.4 0.0051 17.0 1.6 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4606) IPT PF01745.16 EST44611.1 - 0.053 12.9 0.4 0.082 12.3 0.4 1.4 1 0 0 1 1 1 0 Isopentenyl transferase SWIB PF02201.18 EST44611.1 - 0.16 11.9 3.8 0.12 12.3 1.3 2.1 2 0 0 2 2 2 0 SWIB/MDM2 domain CENP-H PF05837.12 EST44611.1 - 0.58 10.6 13.2 0.18 12.2 4.5 2.5 2 1 0 2 2 2 0 Centromere protein H (CENP-H) TSC22 PF01166.18 EST44611.1 - 0.61 10.4 6.9 0.44 10.9 0.3 3.4 3 0 0 3 3 3 0 TSC-22/dip/bun family THP2 PF09432.10 EST44611.1 - 0.78 9.8 13.6 4.6 7.3 0.3 3.2 2 2 1 3 3 3 0 Tho complex subunit THP2 DUF2730 PF10805.8 EST44611.1 - 1 9.5 8.2 7.3 6.7 0.1 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF2730) CorA PF01544.18 EST44611.1 - 1.1 8.5 11.4 1.4 8.1 6.7 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Cep57_MT_bd PF06657.13 EST44611.1 - 1.8 9.0 9.7 3.9 8.0 1.9 2.6 2 1 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Spore_II_R PF09551.10 EST44611.1 - 2 8.9 6.0 1.8 9.0 0.8 2.2 2 0 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) YtxH PF12732.7 EST44612.1 - 0.11 13.1 0.0 1.3 9.6 0.0 2.6 1 1 1 2 2 2 0 YtxH-like protein Glutaredoxin2_C PF04399.13 EST44612.1 - 2.9 7.7 7.6 0.49 10.2 1.7 2.5 2 1 1 3 3 3 0 Glutaredoxin 2, C terminal domain ALMT PF11744.8 EST44612.1 - 3.5 6.3 10.8 4.7 5.9 10.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Synaptonemal_3 PF15191.6 EST44612.1 - 4.6 7.1 7.2 1.1 9.1 0.7 2.8 2 1 0 2 2 2 0 Synaptonemal complex central element protein 3 DASH_Hsk3 PF08227.11 EST44612.1 - 5.3 7.5 14.8 8.5 6.8 6.0 3.6 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like PP2C_C PF07830.13 EST44612.1 - 7.1 7.2 8.0 4.9 7.7 0.2 3.1 2 1 0 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain FYVE PF01363.21 EST44614.1 - 0.0083 16.2 0.1 0.0083 16.2 0.1 2.3 2 0 0 2 2 2 1 FYVE zinc finger VID27 PF08553.10 EST44616.1 - 2.2e-13 50.0 0.7 4e-13 49.2 0.7 1.4 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain DUF2375 PF09558.10 EST44616.1 - 0.0065 16.5 0.1 0.032 14.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2375) GDI PF00996.18 EST44617.1 - 3.9e-148 493.6 0.2 5.7e-148 493.0 0.2 1.2 1 0 0 1 1 1 1 GDP dissociation inhibitor SGS PF05002.15 EST44618.1 - 1.1e-14 54.2 1.5 2.2e-14 53.3 1.5 1.5 1 0 0 1 1 1 1 SGS domain CS PF04969.16 EST44618.1 - 0.00031 21.7 0.6 0.00052 21.0 0.6 1.5 1 0 0 1 1 1 1 CS domain Sedlin_N PF04628.13 EST44618.1 - 0.019 15.1 0.1 0.028 14.5 0.1 1.4 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region TRCF PF03461.15 EST44618.1 - 0.03 14.7 1.1 0.1 13.0 0.6 2.1 1 1 2 3 3 3 0 TRCF domain HtaA PF04213.13 EST44618.1 - 0.05 14.1 0.1 0.063 13.8 0.1 1.2 1 0 0 1 1 1 0 Htaa zf-C3HC4_4 PF15227.6 EST44619.1 - 4.2e-08 33.2 12.8 8.8e-08 32.2 12.8 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 EST44619.1 - 4.7e-07 29.6 12.1 1e-06 28.5 12.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EST44619.1 - 2.8e-05 23.9 11.2 5.8e-05 22.9 11.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EST44619.1 - 3.5e-05 23.6 8.1 7.3e-05 22.5 8.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EST44619.1 - 7.1e-05 22.8 10.6 7.1e-05 22.8 10.6 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EST44619.1 - 8.1e-05 22.5 12.2 0.00017 21.5 12.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EST44619.1 - 0.00015 22.0 11.0 0.00032 21.0 11.0 1.6 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EST44619.1 - 0.0034 17.2 9.7 0.0083 16.0 9.7 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EST44619.1 - 0.02 14.7 4.6 0.059 13.2 4.6 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DZR PF12773.7 EST44619.1 - 0.12 12.4 7.0 0.44 10.6 7.0 1.9 1 0 0 1 1 1 0 Double zinc ribbon zf-rbx1 PF12678.7 EST44619.1 - 0.31 11.4 8.5 0.72 10.2 8.5 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain BLUF PF04940.12 EST44619.1 - 0.37 11.0 2.2 14 5.9 0.1 3.1 3 0 0 3 3 3 0 Sensors of blue-light using FAD Cas_DxTHG PF09455.10 EST44619.1 - 1.6 8.2 8.9 2.3 7.7 6.9 1.8 1 1 1 2 2 2 0 CRISPR-associated (Cas) DxTHG family QIL1 PF15884.5 EST44621.1 - 0.15 12.6 0.5 9.7 6.9 0.1 2.9 1 1 1 2 2 2 0 MICOS complex subunit MIC13, QIL1 DUF1949 PF09186.11 EST44621.1 - 0.33 10.9 2.5 2.7 7.9 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1949) DUF4988 PF16378.5 EST44622.1 - 0.075 12.7 0.9 0.11 12.2 0.8 1.4 1 1 0 1 1 1 0 Domain of unknown function DUF4837 PF16125.5 EST44622.1 - 0.29 10.1 2.8 0.43 9.6 2.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4837) Med21 PF11221.8 EST44622.1 - 2.3 8.5 9.1 3.1 8.0 9.1 1.4 1 1 0 1 1 1 0 Subunit 21 of Mediator complex Spec3 PF15795.5 EST44624.1 - 7.2e-05 23.3 17.3 0.00091 19.7 17.3 2.0 1 1 0 1 1 1 1 Ectodermal ciliogenesis protein ORMDL PF04061.14 EST44624.1 - 0.058 13.2 1.4 0.082 12.7 1.4 1.2 1 0 0 1 1 1 0 ORMDL family Nup54_57_C PF18570.1 EST44625.1 - 0.0047 16.5 0.6 0.013 15.1 0.6 1.7 1 0 0 1 1 1 1 NUP57/Nup54 C-terminal domain DUF1177 PF06675.11 EST44625.1 - 0.06 12.2 0.0 0.089 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1177) DUF4201 PF13870.6 EST44626.1 - 1e-33 116.5 18.4 1e-33 116.5 18.4 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) bZIP_1 PF00170.21 EST44626.1 - 0.011 15.8 20.2 0.53 10.4 0.3 4.9 4 0 0 4 4 4 0 bZIP transcription factor HALZ PF02183.18 EST44626.1 - 0.86 9.9 14.6 16 5.9 0.6 4.8 4 0 0 4 4 4 0 Homeobox associated leucine zipper DUF2408 PF10303.9 EST44626.1 - 2.5 8.7 20.9 0.043 14.4 7.5 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) LPP PF04728.13 EST44626.1 - 2.7 8.4 13.8 7.4 7.0 0.2 4.0 4 0 0 4 4 4 0 Lipoprotein leucine-zipper DUF4407 PF14362.6 EST44626.1 - 3.9 6.7 26.5 0.15 11.4 9.6 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) tRNA-Thr_ED PF08915.11 EST44627.1 - 0.025 14.6 1.1 0.036 14.1 0.9 1.5 1 1 0 1 1 1 0 Archaea-specific editing domain of threonyl-tRNA synthetase SHS2_FTSA PF02491.20 EST44627.1 - 0.041 14.3 0.4 0.096 13.1 0.0 1.7 2 0 0 2 2 2 0 SHS2 domain inserted in FTSA MIEAP PF16026.5 EST44627.1 - 0.71 10.1 5.9 0.19 11.9 2.8 1.6 1 1 1 2 2 2 0 Mitochondria-eating protein RSS_P20 PF11757.8 EST44628.1 - 0.014 15.8 0.2 0.032 14.7 0.2 1.6 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like N-terminal domain Methyltransf_15 PF09445.10 EST44628.1 - 0.37 10.3 2.8 0.21 11.1 0.4 1.7 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase DUF4934 PF16288.5 EST44629.1 - 0.053 13.4 0.3 0.33 10.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4934) ThaI PF15514.6 EST44630.1 - 0.032 13.9 0.8 2.3 7.9 0.0 2.1 1 1 1 2 2 2 0 Restriction endonuclease ThaI LCM PF04072.14 EST44632.1 - 5.7e-20 72.1 0.0 1.4e-19 70.8 0.0 1.6 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Methyltransf_2 PF00891.18 EST44632.1 - 0.017 14.4 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain UspB PF10625.9 EST44633.1 - 0.0066 16.4 0.5 0.0087 16.0 0.5 1.2 1 0 0 1 1 1 1 Universal stress protein B (UspB) MLANA PF14991.6 EST44633.1 - 0.0089 16.3 0.3 0.011 16.0 0.3 1.3 1 0 0 1 1 1 1 Protein melan-A MASE3 PF17159.4 EST44633.1 - 0.022 14.4 0.1 0.028 14.0 0.1 1.1 1 0 0 1 1 1 0 Membrane-associated sensor domain Pkinase PF00069.25 EST44634.1 - 1.5e-43 149.1 13.7 4.6e-41 140.9 3.1 3.7 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EST44634.1 - 9.4e-38 130.0 1.6 1.8e-33 115.9 0.1 3.4 2 1 1 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.6 EST44634.1 - 3.8e-05 23.1 5.2 0.00014 21.3 0.0 3.2 2 1 2 4 4 4 1 Kinase-like Pkinase_fungal PF17667.1 EST44634.1 - 0.0027 16.5 0.1 0.0059 15.4 0.1 1.5 1 0 0 1 1 1 1 Fungal protein kinase AAA_assoc_C PF09821.9 EST44634.1 - 0.063 13.8 0.8 0.17 12.5 0.2 2.1 2 0 0 2 2 2 0 C-terminal AAA-associated domain SNF2_N PF00176.23 EST44635.1 - 9.7e-12 44.3 0.6 1.8e-11 43.4 0.6 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EST44635.1 - 3e-09 37.2 2.4 8.9e-09 35.7 0.0 2.8 2 1 1 3 3 3 1 Helicase conserved C-terminal domain Leucyl-specific PF14795.6 EST44635.1 - 0.24 11.5 0.0 0.51 10.4 0.0 1.5 1 0 0 1 1 1 0 Leucine-tRNA synthetase-specific domain Myb_DNA-binding PF00249.31 EST44638.1 - 1.9e-05 24.7 0.0 3.3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST44638.1 - 2e-05 24.4 0.6 3.9e-05 23.4 0.6 1.5 1 0 0 1 1 1 1 Myb DNA-binding like CPSF100_C PF13299.6 EST44639.1 - 0.045 13.9 0.5 0.061 13.5 0.5 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal MCM6_C PF18263.1 EST44639.1 - 0.076 13.3 4.6 4.2 7.7 1.1 2.9 2 1 0 2 2 2 0 MCM6 C-terminal winged-helix domain DUF4116 PF13475.6 EST44639.1 - 0.078 12.7 0.2 8.4 6.2 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4116) EIF4E-T PF10477.9 EST44639.1 - 0.53 9.1 11.9 0.56 9.0 11.9 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Syntaxin-18_N PF10496.9 EST44639.1 - 1.4 9.2 6.8 1.6 9.0 0.0 3.1 2 1 1 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus Myb_DNA-bind_7 PF15963.5 EST44640.1 - 0.0058 16.5 0.8 0.0093 15.8 0.8 1.3 1 0 0 1 1 1 1 Myb DNA-binding like Ank_5 PF13857.6 EST44641.1 - 1.5e-05 25.1 0.0 0.00072 19.8 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EST44641.1 - 1.6e-05 25.4 0.0 0.0019 18.7 0.0 3.1 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EST44641.1 - 0.0022 18.3 0.0 0.017 15.6 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 EST44641.1 - 0.013 16.1 0.0 0.29 11.8 0.0 2.8 1 1 2 3 3 3 0 Ankyrin repeats (many copies) Lipase_3 PF01764.25 EST44642.1 - 1.1e-11 44.8 0.0 1.5e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Pkinase PF00069.25 EST44643.1 - 3.8e-61 206.8 0.0 7.8e-61 205.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST44643.1 - 5.9e-43 147.0 0.0 9.3e-43 146.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EST44643.1 - 5.3e-06 25.5 0.0 4.6e-05 22.4 0.2 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EST44643.1 - 0.00039 19.8 0.6 0.22 10.8 0.0 3.1 3 1 0 3 3 3 2 Kinase-like DUF3314 PF11771.8 EST44644.1 - 0.00012 22.2 0.0 0.00018 21.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3314) 3-alpha PF03475.14 EST44644.1 - 0.098 12.5 0.1 0.22 11.4 0.1 1.7 1 0 0 1 1 1 0 3-alpha domain WD40 PF00400.32 EST44645.1 - 6.9e-07 29.9 5.9 0.019 15.8 0.0 6.1 7 1 0 7 7 7 2 WD domain, G-beta repeat VirE1 PF12189.8 EST44645.1 - 0.013 15.6 0.2 1.4 9.1 0.0 2.4 1 1 1 2 2 2 0 Single-strand DNA-binding protein DUF2375 PF09558.10 EST44646.1 - 0.017 15.2 0.0 3.3 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2375) AAR2 PF05282.11 EST44646.1 - 0.063 12.7 0.3 0.066 12.6 0.3 1.0 1 0 0 1 1 1 0 AAR2 protein Rubi_NSP_C PF12601.8 EST44647.1 - 0.012 15.7 0.1 0.027 14.6 0.0 1.6 2 0 0 2 2 2 0 Rubivirus non-structural protein Sfi1 PF08457.10 EST44648.1 - 0.043 12.4 7.1 0.051 12.1 7.1 1.1 1 0 0 1 1 1 0 Sfi1 spindle body protein DEAD PF00270.29 EST44650.1 - 2.6e-20 72.9 0.0 4.6e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EST44650.1 - 8.9e-06 25.8 0.0 2.1e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 EST44650.1 - 0.0044 16.1 0.0 0.0069 15.5 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.16 EST44650.1 - 0.0061 16.0 0.0 0.015 14.7 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein Helicase_C PF00271.31 EST44650.1 - 0.059 13.7 0.3 0.51 10.7 0.1 2.6 2 1 0 2 2 2 0 Helicase conserved C-terminal domain RTC_insert PF05189.13 EST44652.1 - 1.2e-15 57.9 0.0 1.9e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.21 EST44652.1 - 3.6e-14 52.5 0.0 7.7e-14 51.4 0.0 1.5 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase Pkinase PF00069.25 EST44653.1 - 4.7e-48 163.8 0.0 5.5e-48 163.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST44653.1 - 2.4e-25 89.3 0.0 3.7e-25 88.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase VSP PF03302.13 EST44657.1 - 4.5e-16 58.7 178.1 6.5e-06 25.3 24.4 6.3 1 1 5 6 6 6 6 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST44657.1 - 2.9e-05 24.2 155.3 0.072 13.2 27.6 9.7 1 1 8 9 9 9 4 Furin-like repeat, cysteine-rich Podoplanin PF05808.11 EST44657.1 - 0.028 14.5 0.7 0.05 13.7 0.7 1.3 1 0 0 1 1 1 0 Podoplanin DUF3042 PF11240.8 EST44657.1 - 0.083 12.9 0.5 0.17 12.0 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) Insulin_TMD PF17870.1 EST44657.1 - 0.16 12.0 0.1 0.35 11.0 0.1 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Aminotran_4 PF01063.19 EST44659.1 - 6.1e-23 81.9 0.1 1.4e-22 80.7 0.1 1.5 1 1 0 1 1 1 1 Amino-transferase class IV TMF_TATA_bd PF12325.8 EST44660.1 - 0.016 15.4 1.7 0.018 15.2 0.3 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF3287 PF11690.8 EST44660.1 - 0.02 14.6 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) DivIC PF04977.15 EST44660.1 - 0.056 13.2 1.3 0.12 12.2 1.3 1.5 1 0 0 1 1 1 0 Septum formation initiator SIX1_SD PF16878.5 EST44660.1 - 0.11 13.1 3.4 1.4 9.5 0.1 2.9 2 2 1 3 3 3 0 Transcriptional regulator, SIX1, N-terminal SD domain HALZ PF02183.18 EST44660.1 - 0.19 12.0 1.5 0.37 11.0 0.9 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper zf-UBR PF02207.20 EST44661.1 - 9.9e-12 44.9 10.7 2.1e-11 43.8 10.7 1.6 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) zf-UBR PF02207.20 EST44663.1 - 5.1e-12 45.8 10.7 8.3e-12 45.1 10.7 1.3 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) TMF_TATA_bd PF12325.8 EST44664.1 - 0.016 15.4 1.7 0.018 15.2 0.3 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF3287 PF11690.8 EST44664.1 - 0.02 14.6 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) DivIC PF04977.15 EST44664.1 - 0.056 13.2 1.3 0.12 12.2 1.3 1.5 1 0 0 1 1 1 0 Septum formation initiator SIX1_SD PF16878.5 EST44664.1 - 0.11 13.1 3.4 1.4 9.5 0.1 2.9 2 2 1 3 3 3 0 Transcriptional regulator, SIX1, N-terminal SD domain HALZ PF02183.18 EST44664.1 - 0.19 12.0 1.5 0.37 11.0 0.9 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper Aminotran_4 PF01063.19 EST44665.1 - 7.8e-23 81.5 0.0 1.7e-22 80.4 0.0 1.5 1 1 0 1 1 1 1 Amino-transferase class IV Cupin_2 PF07883.11 EST44668.1 - 0.13 12.0 0.4 0.21 11.4 0.4 1.3 1 0 0 1 1 1 0 Cupin domain Myb_DNA-binding PF00249.31 EST44669.1 - 7.7e-05 22.8 1.7 0.00012 22.2 1.7 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST44669.1 - 9.4e-05 22.6 0.4 0.00016 21.9 0.2 1.4 1 1 0 1 1 1 1 Myb-like DNA-binding domain SLIDE PF09111.10 EST44669.1 - 0.017 15.2 0.1 0.019 14.9 0.1 1.2 1 0 0 1 1 1 0 SLIDE NAR2 PF16974.5 EST44669.1 - 0.021 14.2 3.7 0.026 13.9 3.7 1.2 1 0 0 1 1 1 0 High-affinity nitrate transporter accessory ARID PF01388.21 EST44669.1 - 0.026 15.2 0.2 0.034 14.8 0.2 1.3 1 1 0 1 1 1 0 ARID/BRIGHT DNA binding domain Myb_DNA-bind_4 PF13837.6 EST44669.1 - 0.057 13.8 5.2 0.29 11.5 5.2 1.9 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain Ribonuc_L-PSP PF01042.21 EST44670.1 - 2.6e-35 121.1 0.1 3e-35 120.9 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Pkinase PF00069.25 EST44671.1 - 2.6e-61 207.3 0.0 4.1e-61 206.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST44671.1 - 2e-38 132.1 0.0 2.8e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EST44671.1 - 1.1e-07 31.5 0.7 0.0013 18.1 0.0 2.8 3 1 0 3 3 3 2 Kinase-like APH PF01636.23 EST44671.1 - 3e-06 27.3 0.1 0.0089 16.0 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EST44671.1 - 4.3e-06 26.2 0.2 9.4e-06 25.1 0.0 1.8 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EST44671.1 - 0.00034 20.3 0.0 0.00083 19.0 0.0 1.5 1 1 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 EST44671.1 - 0.0051 15.8 0.0 0.0086 15.0 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain NB-ARC PF00931.22 EST44671.1 - 0.1 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain HALZ PF02183.18 EST44672.1 - 1.5 9.1 9.1 7.3 6.9 0.3 3.8 3 1 1 4 4 4 0 Homeobox associated leucine zipper DUF4140 PF13600.6 EST44672.1 - 1.7 9.1 14.9 0.23 11.9 0.3 3.2 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) Spc7 PF08317.11 EST44672.1 - 8.5 5.2 27.7 0.055 12.3 11.4 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein MORN PF02493.20 EST44674.1 - 0.026 14.4 15.2 2.5 8.2 0.4 5.2 5 0 0 5 5 5 0 MORN repeat OHCU_decarbox PF09349.10 EST44674.1 - 0.14 12.7 0.4 0.74 10.3 0.0 2.2 2 0 0 2 2 2 0 OHCU decarboxylase Cullin_Nedd8 PF10557.9 EST44674.1 - 0.88 9.7 3.6 0.76 9.9 0.1 2.8 2 0 0 2 2 2 0 Cullin protein neddylation domain Podoplanin PF05808.11 EST44676.1 - 0.025 14.7 3.1 0.051 13.7 3.1 1.6 1 1 0 1 1 1 0 Podoplanin DUF4366 PF14283.6 EST44676.1 - 0.46 10.5 5.0 1.3 9.0 4.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Myb_DNA-bind_7 PF15963.5 EST44677.1 - 0.0047 16.8 1.0 0.0066 16.3 1.0 1.2 1 0 0 1 1 1 1 Myb DNA-binding like Fox-1_C PF12414.8 EST44678.1 - 0.051 14.0 0.2 0.053 13.9 0.2 1.1 1 0 0 1 1 1 0 Calcitonin gene-related peptide regulator C terminal Pox_A11 PF05061.13 EST44678.1 - 0.21 10.9 0.0 0.23 10.7 0.0 1.0 1 0 0 1 1 1 0 Poxvirus A11 Protein DUF3377 PF11857.8 EST44679.1 - 0.013 15.4 3.0 0.013 15.4 3.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Pox_A9 PF04835.12 EST44679.1 - 6 7.1 7.5 1.6 8.9 0.8 2.6 2 0 0 2 2 2 0 A9 protein conserved region PA28_beta PF02252.18 EST44680.1 - 6.7e-08 32.3 0.2 1.4e-07 31.3 0.2 1.4 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit Nuc_sug_transp PF04142.15 EST44681.1 - 0.13 11.4 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Nucleotide-sugar transporter Metallophos PF00149.28 EST44682.1 - 2.6e-33 116.2 0.0 3.7e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase YqgF PF14639.6 EST44683.1 - 0.085 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 Peptidase_C1 PF00112.23 EST44684.1 - 2.4e-30 106.3 3.9 2.8e-30 106.0 3.9 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EST44684.1 - 0.00056 18.8 0.2 0.00081 18.3 0.2 1.2 1 0 0 1 1 1 1 Peptidase C1-like family HRM PF02793.22 EST44684.1 - 0.09 13.1 2.5 7.3 7.0 0.1 2.3 2 0 0 2 2 2 0 Hormone receptor domain Peptidase_C1 PF00112.23 EST44685.1 - 2.2e-27 96.6 5.0 2.5e-27 96.4 5.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EST44685.1 - 0.00026 19.9 0.1 0.00036 19.4 0.1 1.2 1 0 0 1 1 1 1 Peptidase C1-like family HRM PF02793.22 EST44685.1 - 0.048 14.0 2.5 5.3 7.4 0.1 2.4 2 0 0 2 2 2 0 Hormone receptor domain Pkinase PF00069.25 EST44688.1 - 2.7e-62 210.5 0.0 3.4e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST44688.1 - 1.1e-36 126.4 0.0 1.5e-36 126.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EST44688.1 - 0.014 15.3 0.1 0.54 10.1 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Radical_SAM_C PF16199.5 EST44688.1 - 0.037 14.1 0.0 0.078 13.0 0.0 1.5 1 0 0 1 1 1 0 Radical_SAM C-terminal domain Pkinase_fungal PF17667.1 EST44688.1 - 0.11 11.3 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pr_beta_C PF12465.8 EST44691.1 - 0.12 11.8 0.0 0.36 10.3 0.0 1.8 1 0 0 1 1 1 0 Proteasome beta subunits C terminal ANAPC3 PF12895.7 EST44692.1 - 6.4e-22 77.6 23.9 3.3e-10 40.0 6.3 5.6 4 1 1 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EST44692.1 - 1.1e-12 48.2 26.9 0.00096 19.6 1.8 7.7 4 3 5 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 EST44692.1 - 1.2e-09 37.5 30.2 0.059 13.5 0.4 9.3 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_1 PF00515.28 EST44692.1 - 9.3e-09 34.7 26.7 0.16 11.9 0.2 8.4 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 EST44692.1 - 5.3e-08 33.1 34.2 0.059 13.7 0.5 8.0 6 2 1 7 7 7 4 Tetratricopeptide repeat TPR_6 PF13174.6 EST44692.1 - 8.2e-08 32.4 20.1 0.043 14.4 0.0 9.1 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_16 PF13432.6 EST44692.1 - 4.1e-05 24.1 20.0 0.0025 18.4 0.5 5.8 6 1 0 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EST44692.1 - 0.00022 21.0 19.5 0.42 10.8 0.5 7.3 8 1 1 9 9 8 2 Tetratricopeptide repeat TPR_4 PF07721.14 EST44692.1 - 0.00026 21.3 5.4 0.24 12.1 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat PPR_2 PF13041.6 EST44692.1 - 0.0013 18.9 0.7 1.8 8.9 0.0 4.5 4 0 0 4 4 4 1 PPR repeat family TPR_14 PF13428.6 EST44692.1 - 0.0022 18.6 25.2 6.7 7.8 0.0 8.6 5 3 4 10 10 8 1 Tetratricopeptide repeat TPR_11 PF13414.6 EST44692.1 - 0.0031 17.2 4.5 0.0031 17.2 0.3 3.3 3 0 0 3 3 3 1 TPR repeat TPR_8 PF13181.6 EST44692.1 - 0.0036 17.4 22.7 11 6.5 0.0 8.9 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_9 PF13371.6 EST44692.1 - 0.0063 16.6 0.5 0.0063 16.6 0.5 2.7 3 0 0 3 3 2 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EST44692.1 - 0.007 16.4 15.4 0.89 9.6 5.9 5.2 2 2 3 5 5 5 1 Putative TPR-like repeat Mhr1 PF12829.7 EST44692.1 - 0.011 15.8 0.0 0.078 13.1 0.0 2.5 2 0 0 2 2 2 0 Transcriptional regulation of mitochondrial recombination PPR PF01535.20 EST44692.1 - 0.036 14.3 9.5 3.3 8.1 0.2 6.1 7 0 0 7 7 6 0 PPR repeat TPR_10 PF13374.6 EST44692.1 - 0.041 13.8 16.3 1.8 8.6 0.9 6.2 6 0 0 6 6 5 0 Tetratricopeptide repeat PPR_1 PF12854.7 EST44692.1 - 0.096 12.4 1.1 0.43 10.3 0.3 2.6 2 0 0 2 2 2 0 PPR repeat Fis1_TPR_C PF14853.6 EST44692.1 - 0.19 11.8 5.1 31 4.7 0.0 4.8 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat TRIF-NTD PF17798.1 EST44692.1 - 0.2 11.8 5.4 0.3 11.2 0.1 3.5 2 1 4 6 6 6 0 TRIF N-terminal domain TPR_17 PF13431.6 EST44692.1 - 1.4 9.5 12.0 2.6 8.6 0.3 5.4 6 0 0 6 6 4 0 Tetratricopeptide repeat Pr_beta_C PF12465.8 EST44693.1 - 0.12 11.8 0.0 0.36 10.3 0.0 1.8 1 0 0 1 1 1 0 Proteasome beta subunits C terminal OTCace PF00185.24 EST44694.1 - 4.9e-43 146.9 0.2 7.1e-43 146.4 0.2 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 EST44694.1 - 2.3e-39 134.8 0.0 5.4e-39 133.6 0.0 1.6 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain DUF676 PF05057.14 EST44695.1 - 8e-20 71.3 0.1 1.7e-19 70.2 0.1 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EST44695.1 - 0.00012 22.1 0.2 0.00029 20.7 0.2 1.7 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 EST44695.1 - 0.00058 19.3 0.0 0.079 12.3 0.0 2.6 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) Dynamin_N PF00350.23 EST44698.1 - 4e-15 56.3 1.4 6.8e-15 55.5 1.4 1.4 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EST44698.1 - 7.1e-11 42.2 1.6 3.4e-10 40.0 1.3 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EST44698.1 - 9.6e-07 28.5 1.0 6.3e-06 25.9 1.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EST44698.1 - 0.031 14.2 6.9 1.8 8.4 0.1 3.2 2 1 1 3 3 3 0 RsgA GTPase FeoB_N PF02421.18 EST44698.1 - 0.04 13.4 2.6 0.14 11.7 0.3 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B Roc PF08477.13 EST44698.1 - 0.051 13.8 1.9 0.57 10.4 0.0 2.6 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 EST44698.1 - 0.13 11.5 6.2 0.13 11.6 0.4 2.8 1 1 1 2 2 2 0 Septin AIG1 PF04548.16 EST44698.1 - 7.9 5.7 10.5 0.17 11.2 0.5 2.9 3 1 1 4 4 4 0 AIG1 family Fe_dep_repress PF01325.19 EST44699.1 - 0.018 15.2 0.1 0.031 14.5 0.1 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Coatomer_WDAD PF04053.14 EST44704.1 - 3e-08 33.1 0.0 1.2e-06 27.8 0.0 2.5 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 EST44704.1 - 0.016 16.0 0.0 78 4.4 0.0 4.7 5 0 0 5 5 5 0 WD domain, G-beta repeat PQQ_3 PF13570.6 EST44704.1 - 0.019 15.5 1.1 22 5.7 0.0 4.4 5 0 0 5 5 5 0 PQQ-like domain Frtz PF11768.8 EST44704.1 - 0.049 11.9 0.0 0.4 8.9 0.0 2.0 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF3293 PF11697.8 EST44704.1 - 0.15 12.6 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3293) Metallophos PF00149.28 EST44707.1 - 4.1e-29 102.5 0.0 5.1e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EST44707.1 - 0.018 15.2 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Myb_DNA-binding PF00249.31 EST44708.1 - 0.00011 22.3 0.3 0.00032 20.8 0.5 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EST44708.1 - 0.0089 16.2 0.1 0.017 15.3 0.1 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_6 PF13921.6 EST44708.1 - 0.014 15.6 2.8 0.023 14.9 2.7 1.6 1 1 0 1 1 1 0 Myb-like DNA-binding domain Aminopep PF10023.9 EST44708.1 - 0.016 14.6 0.4 0.017 14.5 0.4 1.1 1 0 0 1 1 1 0 Putative aminopeptidase Myb_DNA-bind_5 PF13873.6 EST44708.1 - 0.062 13.4 2.1 0.65 10.1 0.5 2.6 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain SnAPC_2_like PF11035.8 EST44708.1 - 0.11 12.6 4.8 0.11 12.6 2.1 1.8 1 1 1 2 2 2 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb DUF812 PF05667.11 EST44709.1 - 0.0085 15.0 33.6 0.02 13.8 33.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF812) FAM184 PF15665.5 EST44709.1 - 0.33 10.7 42.4 0.052 13.3 26.6 2.7 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B DUF1192 PF06698.11 EST44709.1 - 1.5 9.0 15.3 1.4 9.0 0.2 4.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) DUF745 PF05335.13 EST44709.1 - 2.3 7.9 32.8 0.48 10.1 2.6 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF745) FAA_hydrolase_N PF09298.11 EST44709.1 - 5.7 7.2 11.2 0.41 10.8 1.8 3.0 3 0 0 3 3 3 0 Fumarylacetoacetase N-terminal 4F5 PF04419.14 EST44710.1 - 1.9e-06 28.6 14.2 1.9e-06 28.6 14.2 1.8 2 0 0 2 2 2 1 4F5 protein family Glyco_hydro_77 PF02446.17 EST44712.1 - 2e-09 36.8 0.0 5e-08 32.2 0.0 2.3 1 1 0 1 1 1 1 4-alpha-glucanotransferase AMPK1_CBM PF16561.5 EST44712.1 - 7.3e-05 22.9 0.4 0.00016 21.8 0.0 1.7 2 0 0 2 2 2 1 Glycogen recognition site of AMP-activated protein kinase Peptidase_C1 PF00112.23 EST44714.1 - 1.9e-54 185.0 1.7 2.3e-54 184.8 1.7 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EST44714.1 - 0.033 13.0 3.0 1.7 7.3 0.3 2.7 2 1 1 3 3 3 0 Peptidase C1-like family Cas_Csn2 PF09711.10 EST44716.1 - 0.0025 17.5 3.5 0.0038 16.9 3.4 1.4 1 1 1 2 2 2 1 CRISPR-associated protein (Cas_Csn2) MMADHC PF10229.9 EST44716.1 - 0.032 14.0 0.1 0.038 13.7 0.1 1.1 1 0 0 1 1 1 0 Methylmalonic aciduria and homocystinuria type D protein DUF2577 PF10844.8 EST44716.1 - 0.095 12.9 0.1 0.12 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2577) Peptidase_C1 PF00112.23 EST44717.1 - 1.9e-54 185.0 1.7 2.3e-54 184.8 1.7 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EST44717.1 - 0.033 13.0 3.0 1.7 7.3 0.3 2.7 2 1 1 3 3 3 0 Peptidase C1-like family ArsA_ATPase PF02374.15 EST44718.1 - 1.1e-93 313.8 2.0 1.2e-93 313.6 2.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 EST44718.1 - 2.3e-09 37.4 0.1 5.5e-09 36.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 EST44718.1 - 9.6e-06 25.7 2.4 2.5e-05 24.3 2.4 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 EST44718.1 - 1.3e-05 24.8 0.9 0.0022 17.5 0.1 2.4 2 0 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase AAA_25 PF13481.6 EST44718.1 - 0.00061 19.4 0.0 0.0026 17.3 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EST44718.1 - 0.00063 19.5 0.4 0.0019 18.0 0.3 1.8 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.22 EST44718.1 - 0.00083 19.0 0.3 0.075 12.7 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 EST44718.1 - 0.0084 16.5 0.2 0.045 14.2 0.0 2.3 3 0 0 3 3 3 1 RNA helicase Fer4_NifH PF00142.18 EST44718.1 - 0.016 14.7 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_18 PF13238.6 EST44718.1 - 0.032 14.8 0.2 0.12 12.9 0.1 2.1 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EST44718.1 - 0.035 13.3 0.0 0.072 12.3 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Fer4_12 PF13353.6 EST44718.1 - 0.6 10.4 3.3 1.5 9.1 0.0 2.4 2 1 0 3 3 3 0 4Fe-4S single cluster domain UQ_con PF00179.26 EST44721.1 - 2.2e-44 150.5 0.0 2.9e-44 150.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EST44721.1 - 0.00096 18.9 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EST44721.1 - 0.068 13.5 0.0 0.094 13.0 0.0 1.3 1 0 0 1 1 1 0 RWD domain LRR_8 PF13855.6 EST44723.1 - 4.7e-08 32.7 0.1 0.0013 18.4 0.0 2.6 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EST44723.1 - 0.00046 20.5 0.1 0.63 10.5 0.0 3.0 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EST44723.1 - 0.017 15.6 0.3 49 5.0 0.0 4.7 5 1 0 5 5 5 0 Leucine Rich Repeat LRRNT_2 PF08263.12 EST44723.1 - 0.025 14.9 7.2 0.055 13.8 7.2 1.7 1 1 0 1 1 1 0 Leucine rich repeat N-terminal domain SF-assemblin PF06705.11 EST44725.1 - 1.9e-08 34.0 33.1 6.8e-05 22.3 17.7 2.6 1 1 1 2 2 2 2 SF-assemblin/beta giardin DUF4922 PF16269.5 EST44725.1 - 0.26 11.0 3.0 0.41 10.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4922) Baculo_PEP_C PF04513.12 EST44725.1 - 0.93 9.5 5.8 8.8 6.4 1.8 2.6 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF668 PF05003.12 EST44725.1 - 4.4 7.8 8.4 0.75 10.3 1.4 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF668) Baculo_p24 PF05073.12 EST44725.1 - 4.8 6.9 14.4 4.4 7.1 1.2 2.3 1 1 1 2 2 2 0 Baculovirus P24 capsid protein CRR7 PF12095.8 EST44725.1 - 5.8 7.4 11.8 6.2 7.3 4.5 3.2 2 1 0 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 SapB_1 PF05184.15 EST44726.1 - 0.0044 17.0 1.2 0.01 15.9 0.1 2.3 2 0 0 2 2 2 1 Saposin-like type B, region 1 DUF4449 PF14613.6 EST44726.1 - 0.021 15.0 3.7 0.021 15.0 3.7 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF4449) TcdB_N PF12918.7 EST44726.1 - 0.032 14.5 2.0 0.47 10.8 1.2 2.9 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain SF-assemblin PF06705.11 EST44726.1 - 0.032 13.6 25.7 0.045 13.1 9.4 2.5 1 1 0 2 2 2 0 SF-assemblin/beta giardin Ribosomal_S20p PF01649.18 EST44726.1 - 0.049 14.3 0.4 0.049 14.3 0.4 2.7 2 2 0 2 2 2 0 Ribosomal protein S20 FliG_N PF14842.6 EST44726.1 - 0.23 12.0 8.9 3.6 8.2 1.0 2.8 2 1 1 3 3 3 0 FliG N-terminal domain PIN_6 PF17146.4 EST44726.1 - 0.25 11.9 6.2 0.46 11.0 1.4 2.6 2 1 0 2 2 2 0 PIN domain of ribonuclease DsrC PF04358.13 EST44726.1 - 0.77 10.3 6.5 0.64 10.6 0.9 2.6 3 0 0 3 3 3 0 DsrC like protein DUF2115 PF09888.9 EST44726.1 - 2.3 8.7 12.8 0.16 12.5 4.5 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) Sugar_tr PF00083.24 EST44728.1 - 2.4e-54 184.9 39.2 6.2e-34 117.6 14.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EST44728.1 - 5.3e-21 74.9 46.3 7.3e-16 58.0 28.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EST44728.1 - 5.4e-06 25.9 15.1 2.6e-05 23.7 14.7 2.0 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB TMEM190 PF15431.6 EST44729.1 - 0.039 14.1 1.1 0.057 13.6 0.2 1.7 2 0 0 2 2 2 0 Transmembrane protein 190 CBM_25 PF03423.13 EST44729.1 - 0.14 12.4 0.0 21 5.4 0.0 2.3 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) VSP PF03302.13 EST44733.1 - 3.7e-16 59.0 176.1 5.1e-06 25.6 24.8 6.4 1 1 4 6 6 6 6 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST44733.1 - 2.3e-05 24.5 155.6 0.027 14.6 12.0 9.5 1 1 8 9 9 9 5 Furin-like repeat, cysteine-rich Podoplanin PF05808.11 EST44733.1 - 0.0087 16.2 0.8 0.015 15.4 0.8 1.3 1 0 0 1 1 1 1 Podoplanin DUF3042 PF11240.8 EST44733.1 - 0.083 12.9 0.5 0.17 12.0 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) Insulin_TMD PF17870.1 EST44733.1 - 0.13 12.3 0.1 0.29 11.2 0.1 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF4366 PF14283.6 EST44733.1 - 0.17 11.9 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Ribonuc_L-PSP PF01042.21 EST44734.1 - 2.1e-35 121.3 0.1 2.4e-35 121.2 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP YjgF_endoribonc PF14588.6 EST44734.1 - 0.088 12.9 0.0 0.36 11.0 0.0 2.0 1 1 0 1 1 1 0 YjgF/chorismate_mutase-like, putative endoribonuclease Pkinase PF00069.25 EST44735.1 - 2.6e-61 207.3 0.0 4.1e-61 206.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST44735.1 - 2e-38 132.1 0.0 2.8e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EST44735.1 - 1.1e-07 31.5 0.7 0.0013 18.1 0.0 2.8 3 1 0 3 3 3 2 Kinase-like APH PF01636.23 EST44735.1 - 3e-06 27.3 0.1 0.0089 16.0 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EST44735.1 - 4.3e-06 26.2 0.2 9.4e-06 25.1 0.0 1.8 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EST44735.1 - 0.00034 20.3 0.0 0.00083 19.0 0.0 1.5 1 1 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 EST44735.1 - 0.0051 15.8 0.0 0.0086 15.0 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain NB-ARC PF00931.22 EST44735.1 - 0.1 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Myb_DNA-bind_6 PF13921.6 EST44736.1 - 1.4e-17 63.6 3.2 6.1e-10 39.2 0.2 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EST44736.1 - 9.8e-17 60.9 1.5 2.2e-12 46.9 0.2 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EST44736.1 - 1.1e-05 25.5 0.7 0.00022 21.4 0.1 2.1 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 EST44736.1 - 2.6e-05 24.0 0.8 0.00021 21.1 0.0 2.3 1 1 1 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 EST44736.1 - 0.00033 20.6 0.2 0.025 14.6 0.1 2.0 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_5 PF13873.6 EST44736.1 - 0.0059 16.7 4.5 0.19 11.8 0.8 3.0 1 1 2 3 3 3 2 Myb/SANT-like DNA-binding domain ARID PF01388.21 EST44736.1 - 0.016 15.9 0.1 0.28 11.9 0.1 2.1 2 0 0 2 2 2 0 ARID/BRIGHT DNA binding domain DUF3035 PF11233.8 EST44737.1 - 1.4 9.2 11.2 0.045 14.0 2.9 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3035) SAB PF04382.13 EST44738.1 - 0.2 11.8 0.3 0.56 10.3 0.2 1.7 1 1 1 2 2 2 0 SAB domain TMEM154 PF15102.6 EST44739.1 - 0.00015 21.7 0.3 0.00024 21.0 0.3 1.3 1 0 0 1 1 1 1 TMEM154 protein family DUF4668 PF15701.5 EST44739.1 - 0.00025 20.9 0.6 0.00063 19.6 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4668) Baculo_11_kDa PF06143.11 EST44739.1 - 0.0029 17.1 1.0 0.0058 16.2 1.0 1.4 1 0 0 1 1 1 1 Baculovirus 11 kDa family DUF4199 PF13858.6 EST44739.1 - 0.0059 17.0 0.2 0.0098 16.3 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4199) ECSCR PF15820.5 EST44739.1 - 0.0097 15.7 0.3 0.018 14.9 0.3 1.4 1 0 0 1 1 1 1 Endothelial cell-specific chemotaxis regulator RIFIN PF02009.16 EST44739.1 - 0.02 14.8 0.2 0.02 14.8 0.2 1.2 1 0 0 1 1 1 0 Rifin EphA2_TM PF14575.6 EST44739.1 - 0.023 15.6 0.3 0.037 14.9 0.3 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain AMA-1 PF02430.15 EST44739.1 - 0.033 13.2 0.7 0.039 12.9 0.7 1.1 1 0 0 1 1 1 0 Apical membrane antigen 1 SCIMP PF15050.6 EST44739.1 - 0.038 14.5 0.9 0.081 13.4 0.9 1.4 1 0 0 1 1 1 0 SCIMP protein Pilin_N PF07790.11 EST44739.1 - 0.044 14.7 0.7 0.08 13.9 0.7 1.4 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal DUF5385 PF17359.2 EST44739.1 - 0.054 13.1 1.5 0.078 12.5 1.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Sigma_reg_N PF13800.6 EST44739.1 - 0.058 13.7 2.0 0.14 12.5 2.0 1.6 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF3139 PF11337.8 EST44739.1 - 0.065 13.9 1.7 0.17 12.6 1.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) Wzz PF02706.15 EST44739.1 - 0.072 13.4 3.0 0.21 11.9 0.8 2.2 2 0 0 2 2 2 0 Chain length determinant protein Lig_chan PF00060.26 EST44739.1 - 0.13 12.1 0.3 0.23 11.3 0.3 1.3 1 0 0 1 1 1 0 Ligand-gated ion channel DUF4834 PF16118.5 EST44739.1 - 0.15 13.1 1.2 0.23 12.5 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) FeoB_associated PF12669.7 EST44739.1 - 0.18 12.2 1.1 0.33 11.4 1.1 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Vpu PF00558.19 EST44739.1 - 3.5 7.5 5.1 4.4 7.1 4.3 1.5 1 1 0 1 1 1 0 Vpu protein Kinesin PF00225.23 EST44740.1 - 9.9e-89 297.5 0.1 1.4e-88 297.1 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EST44740.1 - 6.9e-17 61.8 0.0 2e-16 60.3 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding SAM_1 PF00536.30 EST44740.1 - 6.6e-05 23.3 0.2 0.00023 21.6 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PKcGMP_CC PF16808.5 EST44740.1 - 0.08 12.8 2.1 0.1 12.5 0.4 2.0 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Hexapep PF00132.24 EST44742.1 - 0.098 12.4 0.8 5.6 6.8 0.1 2.3 2 0 0 2 2 2 0 Bacterial transferase hexapeptide (six repeats) RRM_3 PF08777.11 EST44743.1 - 1.4e-14 53.9 0.2 2.9e-14 53.0 0.1 1.5 2 0 0 2 2 2 1 RNA binding motif RRM_1 PF00076.22 EST44743.1 - 0.00011 21.9 0.0 0.00021 21.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3877 PF12993.7 EST44743.1 - 0.027 14.3 0.0 0.032 14.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) PHM7_cyt PF14703.6 EST44745.1 - 4.4e-05 23.8 1.2 8.9e-05 22.8 1.2 1.6 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Anoctamin PF04547.12 EST44745.1 - 0.0099 14.8 34.3 0.16 10.8 34.4 2.6 1 1 0 1 1 1 1 Calcium-activated chloride channel CSD PF00313.22 EST44745.1 - 1.2 9.1 4.5 35 4.3 0.1 3.2 3 0 0 3 3 3 0 'Cold-shock' DNA-binding domain RRM_3 PF08777.11 EST44746.1 - 3e-18 65.7 0.2 6e-18 64.8 0.2 1.5 1 0 0 1 1 1 1 RNA binding motif RRM_1 PF00076.22 EST44746.1 - 0.00041 20.1 0.0 0.00076 19.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TBPIP PF07106.13 EST44748.1 - 1e-12 47.8 0.3 1e-12 47.8 0.3 2.0 2 0 0 2 2 2 1 TBPIP/Hop2 winged helix domain TMF_DNA_bd PF12329.8 EST44748.1 - 0.0087 16.0 4.0 0.026 14.5 4.0 1.8 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding GIT_CC PF16559.5 EST44748.1 - 0.0094 15.8 6.9 0.027 14.3 1.5 3.2 2 1 1 3 3 3 1 GIT coiled-coil Rho guanine nucleotide exchange factor LZ3wCH PF18517.1 EST44748.1 - 0.014 15.5 0.1 0.041 14.0 0.1 1.8 1 0 0 1 1 1 0 Leucine zipper with capping helix domain YycI PF09648.10 EST44748.1 - 0.056 13.0 7.6 0.73 9.4 1.3 2.1 2 0 0 2 2 2 0 YycH protein Nop PF01798.18 EST44748.1 - 0.07 12.6 2.3 0.23 10.9 2.2 1.7 2 0 0 2 2 2 0 snoRNA binding domain, fibrillarin ZapB PF06005.12 EST44748.1 - 0.077 13.4 12.8 0.47 10.9 12.8 2.6 1 1 0 1 1 1 0 Cell division protein ZapB bZIP_1 PF00170.21 EST44748.1 - 0.14 12.3 0.1 0.14 12.3 0.1 2.5 3 1 1 4 4 4 0 bZIP transcription factor DivIC PF04977.15 EST44748.1 - 0.98 9.2 8.9 9.6 6.1 8.9 2.6 1 1 0 1 1 1 0 Septum formation initiator Fungal_TACC PF12709.7 EST44748.1 - 1.8 9.1 8.6 2.4 8.7 0.7 3.3 2 1 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins UL16 PF17622.2 EST44753.1 - 0.074 12.7 0.3 0.41 10.3 0.0 1.9 1 1 0 2 2 2 0 Viral unique long protein 16 ComFB PF10719.9 EST44754.1 - 0.0038 17.3 0.0 0.0057 16.7 0.0 1.3 1 0 0 1 1 1 1 Late competence development protein ComFB GST_C PF00043.25 EST44754.1 - 0.0051 17.0 0.1 0.01 16.0 0.1 1.5 1 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain SAT PF16073.5 EST44754.1 - 0.0093 15.7 0.2 0.012 15.4 0.2 1.1 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis GST_C_2 PF13410.6 EST44754.1 - 0.053 13.5 0.0 0.065 13.3 0.0 1.4 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain YpsA PF06908.11 EST44755.1 - 0.0098 15.9 0.5 0.018 15.1 0.5 1.3 1 0 0 1 1 1 1 YspA SLOG family DUF3231 PF11553.8 EST44756.1 - 0.0007 19.3 1.4 0.55 9.9 0.4 3.9 3 0 0 3 3 3 2 Protein of unknown function (DUF3231) Pro_sub2 PF18513.1 EST44756.1 - 0.0097 16.1 0.4 0.05 13.8 0.4 2.3 1 0 0 1 1 1 1 Prodomain subtilisin 2 HI0933_like PF03486.14 EST44756.1 - 0.013 14.2 4.7 0.021 13.6 3.1 2.1 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.14 EST44759.1 - 4.7e-13 49.0 0.0 7.3e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EST44759.1 - 0.0041 17.7 0.0 0.016 15.7 0.0 2.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 EST44759.1 - 0.039 13.3 0.0 0.072 12.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 EST44759.1 - 0.043 13.5 0.0 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AdoHcyase_NAD PF00670.21 EST44759.1 - 0.099 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain WRKY PF03106.15 EST44760.1 - 6.9e-07 29.4 0.3 6.9e-07 29.4 0.3 2.3 2 0 0 2 2 2 1 WRKY DNA -binding domain DUF4224 PF13986.6 EST44761.1 - 0.16 11.9 0.1 0.31 11.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) Tektin PF03148.14 EST44762.1 - 0.0018 17.1 1.4 0.0018 17.1 1.4 2.1 1 1 1 2 2 2 1 Tektin family DUF2746 PF10874.8 EST44762.1 - 0.005 17.2 1.1 0.011 16.2 0.4 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2746) DASH_Spc19 PF08287.11 EST44762.1 - 0.024 14.5 10.4 0.038 13.9 1.5 2.2 1 1 0 2 2 2 0 Spc19 CC2-LZ PF16516.5 EST44762.1 - 0.49 10.8 13.3 0.95 9.9 1.8 2.7 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator bZIP_1 PF00170.21 EST44762.1 - 0.7 10.0 11.1 2.6 8.2 0.4 3.1 2 1 0 2 2 2 0 bZIP transcription factor LPP PF04728.13 EST44762.1 - 0.7 10.3 6.0 2.4 8.6 0.3 3.2 1 1 2 3 3 3 0 Lipoprotein leucine-zipper SlyX PF04102.12 EST44762.1 - 0.74 10.5 9.6 9.1 7.0 1.1 3.3 1 1 2 3 3 3 0 SlyX DivIC PF04977.15 EST44762.1 - 1.1 9.1 16.8 1 9.2 0.7 3.1 2 1 2 4 4 4 0 Septum formation initiator Tup_N PF08581.10 EST44762.1 - 1.5 9.2 11.3 12 6.2 3.8 2.9 1 1 1 3 3 3 0 Tup N-terminal CCDC92 PF14916.6 EST44762.1 - 2.3 8.1 8.1 1.3 8.9 2.4 3.0 2 2 0 2 2 2 0 Coiled-coil domain of unknown function DUF641 PF04859.12 EST44762.1 - 2.9 8.2 10.5 2 8.8 3.6 3.1 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) COMP PF11598.8 EST44762.1 - 3.2 8.3 6.0 8.6 6.9 1.2 3.6 2 1 0 2 2 2 0 Cartilage oligomeric matrix protein NPV_P10 PF05531.12 EST44762.1 - 6.1 7.4 8.1 5.9 7.4 0.9 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein YabA PF06156.13 EST44762.1 - 9.8 6.9 14.4 2 9.1 3.0 2.4 1 1 1 2 2 2 0 Initiation control protein YabA DAO PF01266.24 EST44764.1 - 9.3e-65 219.5 6.4 1.6e-59 202.3 0.0 3.5 3 1 1 4 4 4 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EST44764.1 - 8.5e-26 90.9 2.1 3e-21 75.9 0.1 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DUF1667 PF07892.11 EST44764.1 - 2.5e-21 75.5 0.9 4.9e-21 74.6 0.1 2.0 2 0 0 2 2 1 1 Protein of unknown function (DUF1667) Fer2_BFD PF04324.15 EST44764.1 - 2.5e-12 46.9 1.7 2.5e-12 46.9 1.7 2.7 3 0 0 3 3 3 1 BFD-like [2Fe-2S] binding domain NAD_binding_8 PF13450.6 EST44764.1 - 5.4e-10 39.4 4.7 2e-05 24.7 2.5 3.5 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EST44764.1 - 3.4e-09 36.4 7.2 0.0017 17.7 1.9 4.0 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EST44764.1 - 7.7e-09 35.1 6.0 4.9e-07 29.2 1.2 2.8 3 0 0 3 3 3 2 FAD binding domain HI0933_like PF03486.14 EST44764.1 - 2.8e-08 32.9 10.6 4e-06 25.8 2.3 3.5 4 0 0 4 4 4 2 HI0933-like protein FAD_oxidored PF12831.7 EST44764.1 - 3.9e-08 33.1 8.1 4.9e-07 29.5 5.3 3.4 3 1 1 4 4 4 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EST44764.1 - 4.8e-08 33.4 9.0 0.029 14.9 0.0 5.6 6 0 0 6 6 5 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EST44764.1 - 5.4e-05 22.4 1.7 0.0077 15.4 1.0 2.5 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 EST44764.1 - 0.0021 17.4 5.6 0.01 15.1 0.8 3.3 3 0 0 3 3 3 1 Thi4 family AlaDh_PNT_C PF01262.21 EST44764.1 - 0.0034 16.7 2.2 0.0034 16.7 2.2 2.6 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 EST44764.1 - 0.0038 16.3 10.6 0.28 10.2 2.8 3.0 3 0 0 3 3 3 2 Lycopene cyclase protein FAD_binding_3 PF01494.19 EST44764.1 - 0.0047 16.2 9.2 0.016 14.5 0.9 3.7 4 1 1 5 5 5 1 FAD binding domain 2-Hacid_dh_C PF02826.19 EST44764.1 - 0.0066 15.8 0.7 0.23 10.8 0.1 2.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SO_alpha_A3 PF17806.1 EST44764.1 - 0.0083 16.4 0.0 0.02 15.2 0.0 1.6 1 0 0 1 1 1 1 Sarcosine oxidase A3 domain Lambda_Kil PF06301.11 EST44764.1 - 0.028 14.0 0.0 0.063 12.9 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage lambda Kil protein SpoU_sub_bind PF08032.12 EST44764.1 - 0.029 14.6 0.3 0.13 12.6 0.0 2.2 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding ELFV_dehydrog PF00208.21 EST44764.1 - 0.12 12.1 1.1 0.25 11.0 0.0 2.1 3 0 0 3 3 3 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AdoHcyase_NAD PF00670.21 EST44764.1 - 0.44 10.6 3.6 0.97 9.5 0.0 3.1 3 1 1 4 4 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain SCAMP PF04144.13 EST44766.1 - 0.16 12.3 0.0 0.2 12.0 0.0 1.1 1 0 0 1 1 1 0 SCAMP family AhpC-TSA PF00578.21 EST44769.1 - 3.4e-32 111.0 0.0 4.6e-32 110.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EST44769.1 - 9.1e-11 41.7 0.0 1.4e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EST44769.1 - 5.6e-06 26.1 0.0 1.8e-05 24.5 0.1 1.9 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin DUF4366 PF14283.6 EST44773.1 - 0.045 13.8 3.0 0.15 12.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) PDGLE PF13190.6 EST44773.1 - 0.18 11.7 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 PDGLE domain PARM PF17061.5 EST44773.1 - 0.26 11.4 2.0 0.49 10.5 0.2 2.0 2 0 0 2 2 2 0 PARM SKG6 PF08693.10 EST44773.1 - 3.7 7.0 7.0 7.4 6.1 7.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Ank_2 PF12796.7 EST44774.1 - 1.3e-06 28.9 0.0 6.3e-05 23.5 0.0 2.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EST44774.1 - 0.00066 19.9 0.1 0.0062 16.8 0.4 2.4 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EST44774.1 - 0.0021 18.6 0.2 0.03 14.9 0.1 2.7 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EST44774.1 - 0.0092 16.4 1.1 0.75 10.6 0.1 3.9 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 EST44774.1 - 0.52 10.8 3.7 1.7 9.2 1.0 2.8 2 1 1 3 3 3 0 Ankyrin repeat FKBP_C PF00254.28 EST44775.1 - 3.8e-32 110.5 0.0 4.8e-32 110.1 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Epimerase PF01370.21 EST44776.1 - 1.7e-47 161.9 0.0 2e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EST44776.1 - 1.7e-43 149.3 0.0 2.1e-43 149.0 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EST44776.1 - 1.2e-15 57.2 0.2 1.5e-12 47.1 0.3 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EST44776.1 - 9.9e-13 47.9 0.3 4.6e-12 45.7 0.3 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EST44776.1 - 2.5e-11 43.2 0.0 8.4e-11 41.5 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EST44776.1 - 2.1e-09 37.5 0.0 3.2e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EST44776.1 - 1.7e-08 34.3 0.1 2.5e-08 33.8 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 EST44776.1 - 0.0027 16.9 0.2 0.0087 15.3 0.0 1.8 1 1 1 2 2 2 1 Male sterility protein 3HCDH_N PF02737.18 EST44776.1 - 0.0065 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.25 EST44776.1 - 0.0082 15.6 0.1 0.025 14.0 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EST44776.1 - 0.1 12.1 0.0 0.37 10.3 0.0 1.8 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Ras PF00071.22 EST44778.1 - 3.4e-46 156.8 0.1 4.2e-46 156.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EST44778.1 - 6.9e-30 103.7 0.1 1.1e-29 103.1 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EST44778.1 - 2.3e-14 53.2 0.0 4e-14 52.5 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EST44778.1 - 4.6e-06 26.7 0.0 8.2e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EST44778.1 - 5.3e-06 26.1 0.2 3.6e-05 23.4 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EST44778.1 - 8.9e-05 21.9 0.1 0.00011 21.7 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EST44778.1 - 0.0023 17.8 0.0 1.3 8.9 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EST44778.1 - 0.032 14.0 0.0 0.072 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EST44778.1 - 0.19 12.1 0.0 0.9 9.9 0.0 2.2 1 1 0 1 1 1 0 AAA ATPase domain SF-assemblin PF06705.11 EST44782.1 - 0.00032 20.1 4.4 0.00046 19.6 4.4 1.3 1 0 0 1 1 1 1 SF-assemblin/beta giardin GAS PF13851.6 EST44782.1 - 0.00074 18.9 5.4 0.012 15.0 0.5 2.1 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 EST44782.1 - 0.016 15.2 2.8 0.016 15.2 2.8 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) KASH_CCD PF14662.6 EST44782.1 - 0.063 13.1 8.4 0.14 12.0 4.6 2.4 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Dor1 PF04124.12 EST44782.1 - 0.065 11.9 8.6 0.26 9.9 8.6 2.1 1 1 0 1 1 1 0 Dor1-like family JIP_LZII PF16471.5 EST44782.1 - 0.11 12.6 3.5 2.6 8.3 0.3 2.9 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II UPF0184 PF03670.13 EST44782.1 - 0.22 11.9 1.1 0.57 10.6 0.1 2.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) Fib_alpha PF08702.10 EST44782.1 - 0.68 10.1 10.4 0.31 11.2 6.1 2.2 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family XhlA PF10779.9 EST44782.1 - 0.71 10.1 4.9 4.6 7.5 0.4 3.2 4 0 0 4 4 4 0 Haemolysin XhlA Eaf7 PF07904.13 EST44784.1 - 0.058 13.8 2.8 0.082 13.3 2.8 1.4 1 0 0 1 1 1 0 Chromatin modification-related protein EAF7 Phosphoprotein PF00922.17 EST44784.1 - 1.7 8.2 14.7 0.49 10.0 10.9 1.8 1 1 1 2 2 2 0 Vesiculovirus phosphoprotein Coilin_N PF15862.5 EST44785.1 - 1.3 8.8 6.4 29 4.5 6.4 2.1 1 1 0 1 1 1 0 Coilin N-terminus TMEM154 PF15102.6 EST44786.1 - 0.081 12.8 0.8 0.16 11.9 0.1 1.8 2 0 0 2 2 2 0 TMEM154 protein family Synaptobrevin PF00957.21 EST44786.1 - 0.27 11.0 9.0 0.5 10.2 1.1 2.3 2 0 0 2 2 2 0 Synaptobrevin Phage_Gp23 PF10669.9 EST44786.1 - 1.1 9.5 3.8 0.8 10.1 0.4 2.1 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Vpu PF00558.19 EST44786.1 - 10 6.0 8.1 6 6.7 2.9 2.2 2 0 0 2 2 2 0 Vpu protein Med31 PF05669.12 EST44789.1 - 3.9e-19 68.4 5.2 3.9e-19 68.4 5.2 1.9 1 1 1 2 2 2 1 SOH1 RXT2_N PF08595.11 EST44791.1 - 0.037 14.1 0.1 0.071 13.1 0.1 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal SLC35F PF06027.12 EST44792.1 - 1.1e-12 48.0 25.1 1.8e-12 47.4 25.1 1.3 1 1 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 EST44792.1 - 1.8e-09 37.8 43.9 2e-06 28.0 21.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family AAA PF00004.29 EST44793.1 - 3.3e-88 292.9 0.0 2e-45 154.5 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EST44793.1 - 5.9e-28 96.4 2.6 1e-13 50.8 0.1 3.6 3 0 0 3 3 3 2 AAA+ lid domain CDC48_N PF02359.18 EST44793.1 - 9.7e-17 60.9 0.1 2.6e-16 59.6 0.0 1.8 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 EST44793.1 - 1.6e-11 44.2 0.0 4.4e-05 23.3 0.0 3.1 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EST44793.1 - 1e-09 39.0 0.2 0.0071 16.7 0.0 3.7 2 2 1 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 EST44793.1 - 1.1e-09 38.7 0.0 0.0018 18.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EST44793.1 - 3.2e-08 33.8 0.0 0.00054 20.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EST44793.1 - 2e-07 31.1 0.0 0.0053 16.8 0.0 3.3 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EST44793.1 - 6.9e-07 28.8 0.0 0.017 14.3 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 EST44793.1 - 8.6e-07 29.3 0.1 0.58 10.4 0.0 4.3 2 2 1 3 3 3 2 AAA domain Vps4_C PF09336.10 EST44793.1 - 2.5e-06 27.4 1.4 7.1e-05 22.7 0.1 2.9 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain RNA_helicase PF00910.22 EST44793.1 - 2.6e-06 27.8 0.0 0.086 13.2 0.0 2.9 2 0 0 2 2 2 2 RNA helicase Viral_helicase1 PF01443.18 EST44793.1 - 4.2e-06 26.7 0.0 0.003 17.3 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 EST44793.1 - 1.7e-05 25.4 0.0 0.09 13.3 0.0 3.1 3 0 0 3 3 2 2 AAA domain IstB_IS21 PF01695.17 EST44793.1 - 3.4e-05 23.7 0.0 0.03 14.1 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein ABC_tran PF00005.27 EST44793.1 - 3.5e-05 24.3 0.1 0.5 10.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter Mg_chelatase PF01078.21 EST44793.1 - 5.6e-05 22.6 0.1 0.33 10.3 0.0 3.0 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EST44793.1 - 9.9e-05 22.4 0.0 0.18 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.17 EST44793.1 - 0.00016 21.4 0.2 0.00044 20.0 0.2 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_28 PF13521.6 EST44793.1 - 0.00072 19.8 0.0 1.6 9.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.13 EST44793.1 - 0.0012 18.0 0.0 0.62 9.2 0.0 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF815) AAA_17 PF13207.6 EST44793.1 - 0.0017 18.8 0.0 2.2 8.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EST44793.1 - 0.0026 17.1 0.0 0.76 9.0 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_7 PF12775.7 EST44793.1 - 0.0035 16.9 0.0 1.8 8.0 0.0 2.6 3 0 0 3 3 2 1 P-loop containing dynein motor region NACHT PF05729.12 EST44793.1 - 0.0083 16.0 0.1 3.5 7.5 0.0 3.2 4 0 0 4 4 4 1 NACHT domain Rad17 PF03215.15 EST44793.1 - 0.0093 15.9 0.0 0.23 11.4 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_25 PF13481.6 EST44793.1 - 0.01 15.4 0.1 6.4 6.3 0.0 3.7 3 1 2 5 5 4 0 AAA domain Parvo_NS1 PF01057.17 EST44793.1 - 0.011 14.8 0.0 1.2 8.1 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Cytidylate_kin PF02224.18 EST44793.1 - 0.012 15.4 0.0 0.56 9.9 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase Sigma54_activat PF00158.26 EST44793.1 - 0.013 15.2 0.0 8.3 6.1 0.0 3.3 2 1 0 2 2 2 0 Sigma-54 interaction domain SKI PF01202.22 EST44793.1 - 0.013 15.6 0.0 0.42 10.7 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase Bac_DnaA PF00308.18 EST44793.1 - 0.02 14.8 0.0 5.7 6.7 0.0 2.6 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_29 PF13555.6 EST44793.1 - 0.022 14.5 0.0 8.9 6.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_24 PF13479.6 EST44793.1 - 0.026 14.3 0.0 5.2 6.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain UFD1 PF03152.14 EST44793.1 - 0.026 14.0 0.0 0.056 12.9 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 TsaE PF02367.17 EST44793.1 - 0.027 14.5 0.0 2.7 8.0 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 EST44793.1 - 0.041 13.1 0.0 9.9 5.3 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_11 PF13086.6 EST44793.1 - 0.046 13.5 0.0 7.5 6.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 EST44793.1 - 0.05 12.9 0.1 17 4.7 0.0 3.2 2 1 0 3 3 3 0 KaiC NTPase_1 PF03266.15 EST44793.1 - 0.087 12.7 0.2 2.1 8.2 0.0 2.8 3 0 0 3 3 3 0 NTPase CPT PF07931.12 EST44793.1 - 0.096 12.5 0.1 1.5 8.7 0.1 2.8 2 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein DUF2075 PF09848.9 EST44793.1 - 0.096 11.9 0.0 7.6 5.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.6 EST44793.1 - 0.11 13.0 0.2 19 5.7 0.0 3.0 2 1 0 2 2 2 0 AAA domain E2F_TDP PF02319.20 EST44795.1 - 0.0023 18.0 0.0 0.0047 16.9 0.0 1.5 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Sipho_Gp157 PF05565.11 EST44795.1 - 0.028 14.4 0.1 0.054 13.5 0.1 1.4 1 0 0 1 1 1 0 Siphovirus Gp157 BRE1 PF08647.11 EST44796.1 - 0.0044 17.0 3.4 0.0044 17.0 3.4 2.6 2 1 0 2 2 2 1 BRE1 E3 ubiquitin ligase YlqD PF11068.8 EST44796.1 - 0.55 10.6 9.7 4.8 7.6 0.6 2.2 2 0 0 2 2 2 0 YlqD protein 60KD_IMP PF02096.20 EST44796.1 - 1.2 9.1 5.5 0.45 10.4 2.4 1.8 2 0 0 2 2 2 0 60Kd inner membrane protein OmpH PF03938.14 EST44796.1 - 4.2 7.7 12.9 2.6 8.4 3.2 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Peptidase_C1 PF00112.23 EST44797.1 - 7.1e-27 94.9 1.6 2.2e-26 93.3 1.6 1.7 1 1 0 1 1 1 1 Papain family cysteine protease Myb_DNA-binding PF00249.31 EST44798.1 - 2.2e-07 31.0 0.0 3.7e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST44798.1 - 2.1e-06 27.9 0.1 2.7e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain SUIM_assoc PF16619.5 EST44799.1 - 2.1 8.5 7.4 1.7 8.8 4.7 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 HTH_23 PF13384.6 EST44801.1 - 0.041 13.7 0.6 0.11 12.3 0.1 1.8 2 0 0 2 2 2 0 Homeodomain-like domain cEGF PF12662.7 EST44802.1 - 0.0062 16.4 1.0 0.0062 16.4 1.0 10.1 9 1 0 9 9 9 2 Complement Clr-like EGF-like FYVE_2 PF02318.16 EST44802.1 - 0.0097 16.1 4.8 0.0097 16.1 4.8 8.1 2 1 4 8 8 8 1 FYVE-type zinc finger zf-C2H2_11 PF16622.5 EST44802.1 - 0.016 14.9 0.2 0.016 14.9 0.2 8.2 8 0 0 8 8 8 0 zinc-finger C2H2-type DUF3511 PF12023.8 EST44804.1 - 0.12 12.2 0.5 0.2 11.5 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3511) TK PF00265.18 EST44806.1 - 1.7e-09 37.8 0.0 1.8e-09 37.7 0.0 1.0 1 0 0 1 1 1 1 Thymidine kinase AAA_29 PF13555.6 EST44806.1 - 0.15 11.8 0.1 0.16 11.7 0.1 1.1 1 0 0 1 1 1 0 P-loop containing region of AAA domain LSM PF01423.22 EST44807.1 - 2.1e-11 43.3 0.0 3.3e-11 42.7 0.0 1.3 1 1 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EST44807.1 - 0.016 15.3 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain JIP_LZII PF16471.5 EST44809.1 - 0.024 14.8 6.6 0.053 13.7 4.1 2.3 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II PAP_assoc PF03828.19 EST44810.1 - 1e-11 44.9 1.9 1.3e-10 41.3 0.6 2.5 2 0 0 2 2 2 1 Cid1 family poly A polymerase LSM PF01423.22 EST44811.1 - 2.1e-11 43.3 0.0 3.3e-11 42.7 0.0 1.3 1 1 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EST44811.1 - 0.016 15.3 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain TK PF00265.18 EST44812.1 - 1.1e-57 194.8 0.0 1.2e-57 194.6 0.0 1.0 1 0 0 1 1 1 1 Thymidine kinase AAA_14 PF13173.6 EST44812.1 - 0.00056 19.9 0.0 0.00089 19.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EST44812.1 - 0.0055 16.4 0.0 0.039 13.7 0.1 1.9 1 1 1 2 2 2 1 AAA domain DEAD PF00270.29 EST44813.1 - 1.4e-14 54.3 0.0 2.2e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EST44813.1 - 1.1e-08 35.4 0.0 2.4e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EST44813.1 - 0.0012 18.9 0.0 0.0017 18.4 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SelB-wing_2 PF09106.11 EST44813.1 - 0.38 11.0 1.9 1.9 8.7 0.3 2.5 2 0 0 2 2 2 0 Elongation factor SelB, winged helix Pkinase PF00069.25 EST44814.1 - 6.7e-47 160.1 0.0 1.1e-46 159.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST44814.1 - 2.4e-25 89.3 0.0 4.3e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 EST44814.1 - 0.00056 19.3 0.0 2 8.2 0.0 3.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EST44814.1 - 0.0035 17.8 0.8 3.1 8.3 0.0 3.8 4 0 0 4 4 4 1 EF-hand domain pair Kdo PF06293.14 EST44814.1 - 0.0074 15.7 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EST44814.1 - 0.0098 15.2 0.0 0.028 13.7 0.0 1.8 1 0 0 1 1 1 1 Kinase-like EF-hand_6 PF13405.6 EST44814.1 - 0.013 15.4 0.0 4.5 7.4 0.0 3.3 2 0 0 2 2 2 0 EF-hand domain CCDC53 PF10152.9 EST44815.1 - 0.55 10.6 3.9 8.9 6.7 3.9 2.4 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex Tropomyosin_1 PF12718.7 EST44815.1 - 0.65 10.2 9.0 1.4 9.0 0.2 3.3 3 0 0 3 3 3 0 Tropomyosin like PfkB PF00294.24 EST44816.1 - 3.8e-24 85.5 0.1 6.2e-24 84.8 0.1 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Cas_Csa5 PF09702.10 EST44816.1 - 0.05 13.9 0.1 4 7.7 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csa5) ParA PF10609.9 EST44817.1 - 1.5e-81 273.5 0.1 1.7e-81 273.3 0.1 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EST44817.1 - 1.6e-13 50.8 0.0 9.3e-13 48.4 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EST44817.1 - 1.2e-06 28.6 0.3 4.5e-06 26.7 0.3 2.0 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 EST44817.1 - 2.4e-06 27.0 0.0 1e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_26 PF13500.6 EST44817.1 - 2.1e-05 24.4 0.0 0.00094 19.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EST44817.1 - 0.0033 17.0 0.0 0.0064 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EST44817.1 - 0.012 14.8 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Fer4_NifH PF00142.18 EST44817.1 - 0.019 14.4 0.1 0.22 10.9 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.11 EST44817.1 - 0.019 14.3 0.1 0.073 12.3 0.0 2.0 3 0 0 3 3 3 0 ATPase MipZ NACHT PF05729.12 EST44817.1 - 0.038 13.9 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain SRP54 PF00448.22 EST44817.1 - 0.075 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 EST44817.1 - 0.11 12.4 0.2 0.27 11.1 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase APS_kinase PF01583.20 EST44817.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_16 PF13191.6 EST44817.1 - 0.17 12.2 0.1 0.39 11.1 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain CLP1_P PF16575.5 EST44817.1 - 0.18 11.5 0.2 0.42 10.4 0.2 1.7 1 1 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Metallophos PF00149.28 EST44820.1 - 5.5e-14 53.1 0.0 1e-13 52.2 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Stealth_CR3 PF17102.5 EST44822.1 - 0.074 13.0 0.6 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 Stealth protein CR3, conserved region 3 Peptidase_C34 PF05413.11 EST44822.1 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative closterovirus papain-like endopeptidase Dus PF01207.17 EST44823.1 - 1.8e-40 139.0 0.0 2.5e-40 138.5 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Polbeta PF18765.1 EST44823.1 - 0.054 13.6 0.0 0.34 11.0 0.0 2.2 2 0 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase zf-CCCH_2 PF14608.6 EST44823.1 - 2.5 8.7 14.1 4 8.0 5.7 2.6 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Ribul_P_3_epim PF00834.19 EST44824.1 - 2.8e-57 193.3 0.1 7.7e-30 103.8 0.0 2.0 2 0 0 2 2 2 2 Ribulose-phosphate 3 epimerase family DUF934 PF06073.12 EST44824.1 - 0.029 14.3 0.0 0.061 13.2 0.0 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF934) QRPTase_C PF01729.19 EST44824.1 - 0.13 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain PQQ_2 PF13360.6 EST44825.1 - 0.0005 19.7 8.6 0.19 11.2 0.7 3.6 2 1 1 4 4 4 2 PQQ-like domain PQQ PF01011.21 EST44825.1 - 0.0086 16.0 0.2 1.1 9.3 0.1 4.2 5 0 0 5 5 5 1 PQQ enzyme repeat PUF PF00806.19 EST44826.1 - 0.061 13.0 0.0 3.5 7.5 0.0 3.1 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat TFIIF_beta PF02270.15 EST44826.1 - 0.13 12.4 0.1 8.9 6.5 0.0 3.0 3 0 0 3 3 3 0 TFIIF, beta subunit HTH domain Annexin PF00191.20 EST44827.1 - 1.5e-07 31.4 0.7 7.1e-05 22.8 0.1 2.8 3 0 0 3 3 3 2 Annexin TrwB_AAD_bind PF10412.9 EST44827.1 - 0.0019 17.2 0.0 0.042 12.8 0.0 2.1 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain RNA_pol_Rpb2_6 PF00562.28 EST44828.1 - 2.4e-98 329.7 0.0 8.5e-98 328.0 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_3 PF04565.16 EST44828.1 - 5.9e-25 87.2 0.0 1.6e-24 85.8 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 EST44828.1 - 9.3e-20 70.8 0.9 3.1e-19 69.1 0.9 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_1 PF04563.15 EST44828.1 - 1.4e-19 70.4 0.1 2.8e-19 69.5 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EST44828.1 - 7.4e-18 64.9 1.7 1.4e-17 64.0 1.7 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 EST44828.1 - 0.001 19.0 0.0 0.0029 17.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_4 PF04566.13 EST44828.1 - 0.09 13.1 0.2 0.42 10.9 0.2 2.2 1 1 0 1 1 1 0 RNA polymerase Rpb2, domain 4 zf-TFIIB PF13453.6 EST44828.1 - 0.33 10.3 5.3 0.88 9.0 5.3 1.8 1 0 0 1 1 1 0 Transcription factor zinc-finger Podoplanin PF05808.11 EST44829.1 - 0.01 15.9 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 0 Podoplanin SKG6 PF08693.10 EST44829.1 - 0.012 15.0 1.2 0.021 14.2 1.2 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Rax2 PF12768.7 EST44829.1 - 0.24 10.8 0.0 0.37 10.2 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Adeno_GP19K PF04881.13 EST44830.1 - 0.0007 19.6 1.1 0.26 11.3 0.1 3.2 3 0 0 3 3 3 2 Adenovirus GP19K RNA_pol_Rpb2_6 PF00562.28 EST44831.1 - 1.3e-109 366.9 0.0 1.7e-109 366.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EST44831.1 - 8.2e-26 90.8 0.3 1.4e-25 90.0 0.3 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 EST44831.1 - 8.2e-24 83.8 0.0 2.4e-23 82.3 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 EST44831.1 - 5.7e-18 65.0 0.0 1.3e-17 63.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 EST44831.1 - 1.4e-17 63.6 0.0 4e-17 62.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 EST44831.1 - 4.1e-10 39.6 0.4 9.9e-10 38.3 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_5 PF04567.17 EST44831.1 - 1.8e-08 34.8 0.1 4.4e-08 33.6 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 DUF4219 PF13961.6 EST44831.1 - 0.13 11.9 0.4 2.3 8.0 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) Ribosomal_S3Ae PF01015.18 EST44832.1 - 0.067 12.8 0.4 0.28 10.8 0.1 1.9 2 0 0 2 2 2 0 Ribosomal S3Ae family DUF3959 PF13105.6 EST44832.1 - 0.19 11.2 2.1 0.21 11.0 1.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3959) PUA PF01472.20 EST44833.1 - 2.2e-08 33.9 0.1 3.9e-08 33.2 0.0 1.5 2 0 0 2 2 2 1 PUA domain Pre-PUA PF17832.1 EST44833.1 - 7.2e-05 23.4 2.3 0.00011 22.8 2.3 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain RPN7 PF10602.9 EST44834.1 - 9.6e-09 35.2 4.2 9.6e-09 35.2 4.2 1.5 2 0 0 2 2 2 1 26S proteasome subunit RPN7 Sds3 PF08598.11 EST44834.1 - 0.016 15.2 0.0 0.035 14.1 0.0 1.5 1 1 0 1 1 1 0 Sds3-like COG2 PF06148.11 EST44834.1 - 0.053 13.6 4.9 5.4 7.1 0.1 3.2 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DAP_B PF07930.12 EST44834.1 - 0.089 12.8 0.5 2.1 8.3 0.1 2.5 2 0 0 2 2 2 0 D-aminopeptidase, domain B DUF2851 PF11013.8 EST44834.1 - 0.13 11.3 4.5 0.24 10.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2851) TraD_N PF12615.8 EST44834.1 - 0.32 11.8 7.0 0.55 11.0 0.3 3.3 3 1 1 4 4 4 0 F sex factor protein N terminal PCI PF01399.27 EST44834.1 - 2.4 8.7 6.1 16 6.1 0.0 3.3 3 0 0 3 3 3 0 PCI domain TetR_C_7 PF14246.6 EST44835.1 - 0.049 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 AefR-like transcriptional repressor, C-terminal domain PriCT_1 PF08708.11 EST44836.1 - 0.89 9.3 3.4 2.3 8.0 0.0 2.9 3 0 0 3 3 3 0 Primase C terminal 1 (PriCT-1) DUF4816 PF16086.5 EST44836.1 - 4.9 7.2 5.6 17 5.4 0.3 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4816) Peptidase_M24 PF00557.24 EST44838.1 - 2.7e-47 161.2 0.0 3.4e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EST44838.1 - 4.9e-22 77.9 0.0 8e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain P22_portal PF16510.5 EST44838.1 - 0.031 12.9 0.0 0.043 12.4 0.0 1.1 1 0 0 1 1 1 0 Phage P22-like portal protein Trehalose_PPase PF02358.16 EST44838.1 - 0.15 11.2 0.1 0.25 10.5 0.1 1.3 1 0 0 1 1 1 0 Trehalose-phosphatase RNA_pol_Rpb2_7 PF04560.20 EST44841.1 - 1.4e-11 44.6 0.3 2.1e-11 44.1 0.1 1.4 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 zf-TFIIB PF13453.6 EST44841.1 - 0.68 9.3 11.2 0.064 12.6 4.5 2.5 2 1 1 3 3 3 0 Transcription factor zinc-finger T3SS_needle_F PF09392.10 EST44842.1 - 0.0094 16.1 3.9 0.02 15.1 3.1 2.0 1 1 0 1 1 1 1 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF SlyX PF04102.12 EST44842.1 - 0.11 13.1 7.5 0.14 12.8 4.2 3.0 2 0 0 2 2 2 0 SlyX FlaC_arch PF05377.11 EST44842.1 - 1.4 9.4 5.6 0.91 10.0 2.1 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) eIF-4B PF06273.11 EST44842.1 - 5.5 5.9 5.6 2 7.4 2.4 1.6 1 1 0 2 2 2 0 Plant specific eukaryotic initiation factor 4B NMD3 PF04981.13 EST44844.1 - 8.3e-52 176.1 10.4 1.4e-51 175.3 10.4 1.4 1 0 0 1 1 1 1 NMD3 family DZR PF12773.7 EST44844.1 - 9.8 6.3 18.1 3.1e+02 1.5 15.0 3.5 2 1 0 2 2 2 0 Double zinc ribbon DUF4748 PF15932.5 EST44846.1 - 0.068 12.9 0.7 0.14 12.0 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) VSP PF03302.13 EST44846.1 - 0.21 10.4 84.0 0.15 10.9 31.7 3.6 1 1 1 2 2 2 0 Giardia variant-specific surface protein TBCC_N PF16752.5 EST44847.1 - 1.8 9.0 5.1 23 5.4 1.0 2.8 2 2 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain adh_short PF00106.25 EST44848.1 - 3.6e-11 42.9 0.0 5.6e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EST44848.1 - 4.3e-06 26.8 0.0 6.7e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EST44848.1 - 0.0012 18.7 0.0 0.0054 16.6 0.0 2.0 3 0 0 3 3 3 1 NAD(P)H-binding adh_short_C2 PF13561.6 EST44848.1 - 0.0067 16.0 0.0 0.0089 15.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase AhpC-TSA PF00578.21 EST44856.1 - 0.044 13.7 0.5 0.26 11.2 0.2 2.6 2 0 0 2 2 2 0 AhpC/TSA family BTB_2 PF02214.22 EST44856.1 - 0.51 10.7 5.6 1.8 9.0 0.0 3.7 3 0 0 3 3 3 0 BTB/POZ domain Trigger_N PF05697.13 EST44858.1 - 0.13 12.6 0.1 2.4 8.5 0.0 2.2 1 1 1 2 2 2 0 Bacterial trigger factor protein (TF) SCF PF02404.15 EST44859.1 - 0.11 11.9 0.1 0.13 11.6 0.1 1.1 1 0 0 1 1 1 0 Stem cell factor Peripla_BP_2 PF01497.18 EST44859.1 - 0.17 11.4 0.0 0.21 11.1 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein DUF1667 PF07892.11 EST44862.1 - 1.9e-16 59.9 0.1 3.1e-16 59.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1667) NRIP1_repr_1 PF15687.5 EST44862.1 - 0.026 14.2 0.1 0.032 13.9 0.1 1.1 1 0 0 1 1 1 0 Nuclear receptor-interacting protein 1 repression 1 Frataxin_Cyay PF01491.16 EST44864.1 - 3.9e-07 30.1 0.1 6.6e-07 29.4 0.1 1.5 1 1 0 1 1 1 1 Frataxin-like domain Frataxin_Cyay PF01491.16 EST44865.1 - 3.9e-07 30.1 0.1 6.6e-07 29.4 0.1 1.5 1 1 0 1 1 1 1 Frataxin-like domain Glucosamine_iso PF01182.20 EST44866.1 - 4.7e-21 75.7 0.0 7e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase HTH_23 PF13384.6 EST44867.1 - 0.001 18.8 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_1 PF01527.20 EST44867.1 - 0.0025 18.1 0.0 0.005 17.1 0.0 1.5 1 0 0 1 1 1 1 Transposase Myb_DNA-binding PF00249.31 EST44867.1 - 0.003 17.7 0.0 0.0074 16.5 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Death PF00531.22 EST44867.1 - 0.0032 17.6 0.0 0.027 14.6 0.0 2.5 2 1 2 4 4 4 1 Death domain HTH_17 PF12728.7 EST44867.1 - 0.028 14.6 0.0 0.068 13.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_1_2 PF13022.6 EST44867.1 - 0.047 13.8 0.2 0.069 13.3 0.2 1.5 1 1 0 1 1 1 0 Helix-turn-helix of insertion element transposase Chordopox_G2 PF05796.12 EST44867.1 - 0.052 13.0 0.0 0.068 12.6 0.0 1.2 1 0 0 1 1 1 0 Chordopoxvirus protein G2 Phage_CI_repr PF07022.13 EST44867.1 - 0.081 13.0 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain TetR_N PF00440.23 EST44867.1 - 0.1 12.4 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family HTH_10 PF04967.12 EST44867.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 HTH DNA binding domain MRP-L51 PF10244.9 EST44867.1 - 0.15 12.3 0.1 0.41 10.9 0.0 1.8 1 1 0 2 2 2 0 Mitochondrial ribosomal subunit HTH_28 PF13518.6 EST44867.1 - 0.15 12.2 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Myb_DNA-bind_6 PF13921.6 EST44867.1 - 0.16 12.3 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain MerR PF00376.23 EST44867.1 - 0.16 11.8 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 MerR family regulatory protein SLC35F PF06027.12 EST44868.1 - 3.7e-05 23.4 15.3 0.00021 20.9 15.3 2.2 1 1 0 1 1 1 1 Solute carrier family 35 Nuc_sug_transp PF04142.15 EST44868.1 - 0.0014 17.8 1.8 0.0025 17.1 1.8 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 EST44868.1 - 0.011 15.9 9.8 0.011 15.9 9.8 3.4 2 2 0 2 2 2 0 EamA-like transporter family CytB6-F_Fe-S PF08802.10 EST44868.1 - 4.9 7.3 6.4 3.8 7.6 0.5 2.8 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit F5_F8_type_C PF00754.25 EST44870.1 - 3e-05 24.1 0.0 6.5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain XhlA PF10779.9 EST44870.1 - 0.2 11.9 3.1 1.3 9.2 1.8 2.6 2 0 0 2 2 2 0 Haemolysin XhlA DUF3136 PF11334.8 EST44872.1 - 0.053 13.3 0.0 0.083 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) Frataxin_Cyay PF01491.16 EST44873.1 - 1.3e-06 28.5 0.1 1.4e-06 28.4 0.1 1.2 1 0 0 1 1 1 1 Frataxin-like domain Frataxin_Cyay PF01491.16 EST44874.1 - 9.9e-07 28.8 0.1 1.1e-06 28.7 0.1 1.2 1 0 0 1 1 1 1 Frataxin-like domain Tubulin PF00091.25 EST44877.1 - 1e-68 231.4 0.0 1.7e-68 230.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EST44877.1 - 1.8e-40 138.0 0.0 2.7e-40 137.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EST44877.1 - 5.1e-05 23.6 0.0 0.00021 21.6 0.0 1.9 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EST44877.1 - 0.0045 16.7 0.0 0.0082 15.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 EST44877.1 - 0.014 14.6 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 Tubulin like Zip PF02535.22 EST44878.1 - 3.3e-25 89.0 13.2 1.3e-24 87.1 13.2 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter Myb_DNA-bind_7 PF15963.5 EST44879.1 - 1.7e-05 24.6 2.4 2.9e-05 23.9 2.4 1.4 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 EST44879.1 - 0.0019 18.4 0.0 0.0073 16.5 0.0 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain SLIDE PF09111.10 EST44879.1 - 0.011 15.8 0.5 0.013 15.5 0.5 1.3 1 1 0 1 1 1 0 SLIDE SANT_DAMP1_like PF16282.5 EST44879.1 - 0.027 14.7 0.2 0.039 14.1 0.2 1.2 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Tiam_CC_Ex PF18385.1 EST44879.1 - 0.046 14.1 0.6 0.061 13.7 0.6 1.3 1 0 0 1 1 1 0 T-lymphoma invasion and metastasis CC-Ex domain Myb_DNA-bind_6 PF13921.6 EST44879.1 - 0.067 13.5 0.3 0.13 12.5 0.2 1.6 2 0 0 2 2 2 0 Myb-like DNA-binding domain NAD_binding_8 PF13450.6 EST44881.1 - 2.4e-10 40.5 0.1 7.3e-10 38.9 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EST44881.1 - 1.5e-08 34.2 0.1 2.5e-08 33.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 EST44881.1 - 8.3e-07 28.6 0.0 2.3e-05 23.9 0.0 2.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 EST44881.1 - 2.4e-05 24.1 0.1 0.00094 18.9 0.0 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EST44881.1 - 7.7e-05 22.1 0.1 0.00019 20.8 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EST44881.1 - 0.00014 20.7 0.1 0.003 16.3 0.3 2.3 2 0 0 2 2 2 1 HI0933-like protein GMC_oxred_N PF00732.19 EST44881.1 - 0.00022 20.7 0.1 0.0041 16.6 0.1 2.1 2 0 0 2 2 2 1 GMC oxidoreductase Thi4 PF01946.17 EST44881.1 - 0.00082 18.7 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 EST44881.1 - 0.0012 18.2 0.0 0.0021 17.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EST44881.1 - 0.0091 15.3 0.2 0.016 14.5 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain GBP_PSP PF02425.15 EST44881.1 - 0.11 12.2 1.4 0.29 10.8 1.4 1.7 1 0 0 1 1 1 0 Paralytic/GBP/PSP peptide Pyr_redox_3 PF13738.6 EST44881.1 - 0.12 11.6 0.2 0.26 10.5 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase BRCT PF00533.26 EST44881.1 - 0.12 12.8 0.2 0.5 10.8 0.1 2.2 3 0 0 3 3 2 0 BRCA1 C Terminus (BRCT) domain VSP PF03302.13 EST44883.1 - 5e-16 58.6 305.4 2.2e-06 26.8 31.6 12.0 1 1 11 12 12 12 10 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST44883.1 - 5.2e-06 26.6 292.1 0.0025 17.9 24.6 14.0 1 1 10 12 12 12 8 Furin-like repeat, cysteine-rich Yippee-Mis18 PF03226.14 EST44885.1 - 0.037 14.2 0.1 0.058 13.6 0.1 1.4 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Rad60-SLD PF11976.8 EST44886.1 - 0.00065 19.5 0.1 0.0042 16.9 0.0 2.5 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like HSL_N PF06350.12 EST44886.1 - 0.0067 15.4 1.6 0.0094 15.0 1.6 1.2 1 0 0 1 1 1 1 Hormone-sensitive lipase (HSL) N-terminus ZapB PF06005.12 EST44887.1 - 3.2 8.3 31.7 3 8.3 1.0 4.6 3 2 1 4 4 4 0 Cell division protein ZapB TSC22 PF01166.18 EST44887.1 - 7.3 7.0 15.3 0.94 9.8 0.7 3.8 3 0 0 3 3 3 0 TSC-22/dip/bun family YabA PF06156.13 EST44887.1 - 8 7.2 23.5 3.8 8.2 3.6 4.5 2 1 2 4 4 4 0 Initiation control protein YabA UQ_con PF00179.26 EST44888.1 - 2.6e-46 156.7 0.0 3.1e-46 156.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EST44888.1 - 0.0011 18.7 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EST44888.1 - 0.0019 18.4 0.0 0.0026 18.0 0.0 1.3 1 0 0 1 1 1 1 RWD domain UFC1 PF08694.11 EST44888.1 - 0.058 13.0 0.0 0.088 12.4 0.0 1.5 1 1 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 UEV PF05743.13 EST44888.1 - 0.066 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 UEV domain LSM PF01423.22 EST44889.1 - 2.4e-12 46.4 0.2 3.2e-12 45.9 0.2 1.2 1 1 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EST44889.1 - 0.0092 16.1 0.1 0.0096 16.0 0.1 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain Hfq PF17209.3 EST44889.1 - 0.04 13.6 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 Hfq protein FUSC PF04632.12 EST44890.1 - 0.0029 16.2 3.2 0.0033 16.0 3.2 1.0 1 0 0 1 1 1 1 Fusaric acid resistance protein family DUF4271 PF14093.6 EST44890.1 - 0.013 15.4 7.9 0.037 14.0 7.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4271) DUF4233 PF14017.6 EST44890.1 - 0.17 12.2 5.7 0.083 13.2 3.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4233) DUF4191 PF13829.6 EST44890.1 - 0.72 9.1 6.1 0.79 9.0 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4191) ArdA PF07275.11 EST44891.1 - 0.084 13.5 1.1 0.15 12.7 0.8 1.7 2 0 0 2 2 2 0 Antirestriction protein (ArdA) DUF4576 PF15144.6 EST44893.1 - 0.012 15.5 0.4 4.6 7.2 0.0 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4576) ATG16 PF08614.11 EST44894.1 - 2.5e-09 37.6 84.0 1.7e-06 28.4 24.1 10.7 1 1 8 10 10 10 5 Autophagy protein 16 (ATG16) Lebercilin PF15619.6 EST44894.1 - 0.00069 19.3 18.8 0.00069 19.3 18.8 10.5 4 3 4 9 9 9 3 Ciliary protein causing Leber congenital amaurosis disease Bcr-Abl_Oligo PF09036.10 EST44894.1 - 0.0028 17.6 0.8 0.0028 17.6 0.8 4.4 4 0 0 4 4 4 1 Bcr-Abl oncoprotein oligomerisation domain TSC22 PF01166.18 EST44894.1 - 0.34 11.3 89.3 4 7.8 0.2 17.5 8 2 13 21 21 21 0 TSC-22/dip/bun family Glyco_trans_A_1 PF09318.10 EST44895.1 - 0.011 15.5 1.8 0.011 15.5 1.8 2.7 3 0 0 3 3 3 0 Glycosyl transferase 1 domain A HU-CCDC81_bac_2 PF18175.1 EST44895.1 - 0.49 10.3 5.6 0.19 11.6 1.6 2.5 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 2 DUF5505 PF17610.2 EST44895.1 - 2.9 7.9 11.8 1.4 8.9 0.1 2.8 2 1 1 3 3 3 0 Family of unknown function (DUF5505) DUF2808 PF10989.8 EST44896.1 - 0.48 10.4 3.7 0.32 11.0 0.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2808) DivIVA PF05103.13 EST44896.1 - 0.52 10.4 15.5 6.9 6.8 15.5 2.3 1 1 0 1 1 1 0 DivIVA protein DUF16 PF01519.16 EST44896.1 - 2.8 8.5 15.4 6 7.4 3.0 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 AAA PF00004.29 EST44897.1 - 1.4e-43 148.5 0.0 4.8e-43 146.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EST44897.1 - 2.1e-13 49.9 1.9 1.2e-12 47.5 0.3 2.6 3 0 0 3 3 3 1 AAA+ lid domain AAA_22 PF13401.6 EST44897.1 - 9.3e-07 29.2 0.9 0.0094 16.2 0.2 2.7 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.14 EST44897.1 - 1.2e-06 28.7 0.0 2.2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EST44897.1 - 5.6e-06 26.4 0.1 3.7e-05 23.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EST44897.1 - 5.9e-06 26.8 0.0 1.2e-05 25.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EST44897.1 - 0.00013 22.1 0.0 0.00027 21.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EST44897.1 - 0.00048 20.5 0.0 0.0055 17.1 0.0 2.2 2 0 0 2 2 2 1 RNA helicase RuvB_N PF05496.12 EST44897.1 - 0.00052 19.8 0.0 0.0016 18.2 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 EST44897.1 - 0.00054 19.7 0.0 0.00093 19.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein ABC_tran PF00005.27 EST44897.1 - 0.0012 19.3 0.1 0.0049 17.4 0.0 2.0 2 1 0 2 2 2 1 ABC transporter Prot_ATP_ID_OB PF16450.5 EST44897.1 - 0.0019 18.1 0.1 0.0051 16.7 0.0 1.8 2 0 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 EST44897.1 - 0.002 18.6 3.6 0.034 14.5 0.1 2.7 2 1 0 3 3 2 1 AAA ATPase domain AAA_28 PF13521.6 EST44897.1 - 0.0037 17.5 0.0 0.008 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 EST44897.1 - 0.0061 15.8 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 EST44897.1 - 0.016 15.2 0.0 0.037 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EST44897.1 - 0.02 14.5 0.6 0.31 10.6 0.2 2.3 1 1 0 2 2 2 0 AAA domain NACHT PF05729.12 EST44897.1 - 0.022 14.7 0.2 1 9.3 0.0 2.4 1 1 1 2 2 2 0 NACHT domain AAA_17 PF13207.6 EST44897.1 - 0.03 14.8 0.0 0.071 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EST44897.1 - 0.032 13.6 0.5 0.18 11.1 0.0 2.2 2 1 1 3 3 3 0 KaiC Mg_chelatase PF01078.21 EST44897.1 - 0.033 13.6 0.0 0.072 12.5 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EST44897.1 - 0.034 14.0 0.0 0.074 12.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 EST44897.1 - 0.041 13.0 0.0 0.075 12.1 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 EST44897.1 - 0.043 13.3 0.5 0.23 10.9 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein NTPase_1 PF03266.15 EST44897.1 - 0.049 13.5 0.0 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 NTPase TsaE PF02367.17 EST44897.1 - 0.051 13.6 0.0 0.096 12.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EST44897.1 - 0.064 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 EST44897.1 - 0.092 11.9 0.0 0.2 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 EST44897.1 - 0.11 12.3 0.1 0.41 10.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain Metalloenzyme PF01676.18 EST44899.1 - 2.1e-72 243.5 0.0 2.4e-72 243.3 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.13 EST44899.1 - 2e-54 184.3 0.0 2.8e-54 183.8 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.22 EST44899.1 - 0.0025 17.5 0.0 0.0041 16.8 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase NGP1NT PF08153.12 EST44899.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 NGP1NT (NUC091) domain Phage_GP20 PF06810.11 EST44900.1 - 0.0054 16.5 1.7 0.0054 16.5 1.7 1.2 1 0 0 1 1 1 1 Phage minor structural protein GP20 NPV_P10 PF05531.12 EST44900.1 - 0.018 15.5 0.2 0.021 15.3 0.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 EST44900.1 - 0.021 15.1 1.8 0.023 15.0 1.6 1.3 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIVA PF05103.13 EST44900.1 - 0.028 14.5 1.6 0.03 14.4 1.6 1.2 1 0 0 1 1 1 0 DivIVA protein HIT PF01230.23 EST44901.1 - 0.00084 20.0 1.0 0.47 11.2 0.6 2.3 2 0 0 2 2 2 2 HIT domain PHD_like PF12910.7 EST44901.1 - 0.056 13.5 4.4 0.96 9.5 0.3 2.2 1 1 1 2 2 2 0 Antitoxin of toxin-antitoxin, RelE / RelB, TA system Vac_Fusion PF02346.16 EST44901.1 - 0.071 12.7 0.1 0.5 10.0 0.0 2.4 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 Fib_alpha PF08702.10 EST44901.1 - 2.6 8.2 10.3 1.6 8.9 7.3 2.1 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Pescadillo_N PF06732.11 EST44905.1 - 9.7e-70 235.2 1.2 1.7e-69 234.4 1.2 1.3 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT_2 PF16589.5 EST44905.1 - 6.3e-09 36.1 0.0 1.5e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Borrelia_orfD PF02999.14 EST44905.1 - 0.023 15.0 1.4 1.5 9.2 0.0 3.2 3 0 0 3 3 3 0 Borrelia orf-D family BRCT PF00533.26 EST44905.1 - 0.033 14.6 0.2 0.16 12.4 0.0 2.3 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain LLC1 PF14945.6 EST44906.1 - 0.086 13.4 0.4 0.39 11.3 0.1 1.9 1 1 1 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein KH_8 PF17903.1 EST44908.1 - 2.6e-06 27.4 0.0 4.9e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 EST44908.1 - 4.2e-05 23.3 0.9 8.9e-05 22.3 0.9 1.7 1 0 0 1 1 1 1 KH domain DUF4268 PF14088.6 EST44908.1 - 0.037 13.9 0.1 0.062 13.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4268) Nitroreductase PF00881.24 EST44909.1 - 9.9e-20 71.3 0.0 1.4e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 Nitroreductase family Fer4 PF00037.27 EST44909.1 - 2.9e-11 42.7 12.8 6.4e-06 25.8 2.6 2.8 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 EST44909.1 - 2.2e-09 37.0 14.4 3.1e-05 23.9 3.5 2.9 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EST44909.1 - 2.8e-09 37.4 11.4 1.2e-08 35.3 11.5 2.1 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EST44909.1 - 2.3e-08 34.8 6.8 0.0013 19.6 0.3 2.7 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 EST44909.1 - 3.7e-08 33.4 10.1 1.2e-07 31.8 10.1 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 EST44909.1 - 1.4e-07 31.5 9.8 1.4e-07 31.5 9.8 2.4 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 EST44909.1 - 9.3e-07 28.9 22.8 2.8e-05 24.1 12.9 2.7 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 EST44909.1 - 2e-06 27.8 18.4 0.00081 19.7 2.8 3.7 4 0 0 4 4 3 2 4Fe-4S binding domain Fer4_2 PF12797.7 EST44909.1 - 3.8e-06 26.7 13.3 0.012 15.6 2.8 3.2 2 0 0 2 2 2 2 4Fe-4S binding domain TM1586_NiRdase PF14512.6 EST44909.1 - 0.00026 20.6 0.3 0.15 11.6 0.0 2.5 1 1 0 2 2 2 2 Putative TM nitroreductase Fer4_22 PF17179.4 EST44909.1 - 0.0015 19.4 5.6 0.7 10.8 0.4 2.7 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 EST44909.1 - 0.0033 17.9 13.1 0.23 12.0 1.5 2.7 2 1 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_8 PF13183.6 EST44909.1 - 0.0071 16.8 16.5 0.48 10.9 4.5 2.8 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 EST44909.1 - 0.049 14.2 12.7 0.8 10.3 1.9 2.8 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 EST44909.1 - 0.12 13.4 5.6 0.12 13.4 5.6 3.5 4 0 0 4 4 2 0 4Fe-4S binding domain Peptidase_C1 PF00112.23 EST44910.1 - 2.8e-21 76.6 0.8 1e-20 74.8 0.8 1.9 1 1 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EST44910.1 - 0.011 14.6 0.6 0.025 13.4 0.2 1.7 2 0 0 2 2 2 0 Peptidase C1-like family CTV_P6 PF06706.11 EST44910.1 - 0.094 12.4 0.3 0.22 11.2 0.3 1.6 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein Collagen_bind_2 PF12904.7 EST44911.1 - 0.001 19.0 9.1 6.8 6.7 0.0 4.9 1 1 4 5 5 5 4 Putative collagen-binding domain of a collagenase Defensin_propep PF00879.18 EST44911.1 - 3.9 7.8 11.6 57 4.1 0.1 5.2 7 0 0 7 7 7 0 Defensin propeptide Ribosomal_S21e PF01249.18 EST44912.1 - 3.7e-28 97.5 0.1 4.1e-28 97.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e DUF3907 PF13047.6 EST44913.1 - 0.045 13.7 2.3 0.45 10.5 0.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3907) PAH PF02671.21 EST44913.1 - 0.61 10.3 7.7 0.61 10.3 0.3 3.9 4 0 0 4 4 4 0 Paired amphipathic helix repeat DUF1240 PF06836.12 EST44913.1 - 4.5 7.9 7.9 8.2 7.0 0.1 3.8 3 2 1 4 4 4 0 Protein of unknown function (DUF1240) PP2C PF00481.21 EST44915.1 - 0.018 14.7 0.1 0.081 12.5 0.0 1.9 2 0 0 2 2 2 0 Protein phosphatase 2C Pro_isomerase PF00160.21 EST44916.1 - 7.6e-30 104.3 0.0 8.4e-30 104.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.21 EST44917.1 - 7.6e-30 104.3 0.0 8.4e-30 104.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PP2C PF00481.21 EST44918.1 - 0.018 14.7 0.1 0.081 12.5 0.0 1.9 2 0 0 2 2 2 0 Protein phosphatase 2C zf-C2H2 PF00096.26 EST44920.1 - 4.5e-21 74.1 32.8 2.4e-05 24.6 0.2 5.3 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EST44920.1 - 9e-21 72.8 29.9 0.00042 20.9 0.1 5.3 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EST44920.1 - 1.1e-09 38.2 26.8 0.0099 16.3 0.2 6.3 6 0 0 6 6 6 3 Zinc-finger double domain zf-met PF12874.7 EST44920.1 - 5e-09 36.2 22.4 0.14 12.6 0.8 5.5 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EST44920.1 - 1.8e-08 34.5 27.1 0.011 16.0 0.9 5.8 6 0 0 6 6 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EST44920.1 - 7.2e-06 26.3 26.6 0.075 13.4 1.8 5.0 1 1 4 5 5 5 3 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 EST44920.1 - 3.3e-05 23.7 34.1 0.14 12.2 1.8 5.9 5 1 0 5 5 5 3 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 EST44920.1 - 3.6e-05 23.8 23.2 0.14 12.3 5.9 5.0 2 1 3 5 5 5 4 Zinc ribbon domain Elf1 PF05129.13 EST44920.1 - 4.5e-05 23.4 2.0 4.5e-05 23.4 2.0 3.8 2 2 1 3 3 3 2 Transcription elongation factor Elf1 like zf-C2H2_11 PF16622.5 EST44920.1 - 7.9e-05 22.3 21.4 0.063 13.0 0.9 4.6 5 0 0 5 5 4 3 zinc-finger C2H2-type zf_UBZ PF18439.1 EST44920.1 - 0.00016 21.2 17.7 0.9 9.2 0.1 5.4 5 0 0 5 5 5 3 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 EST44920.1 - 0.00041 20.6 2.1 0.00041 20.6 2.1 3.4 2 2 2 4 4 4 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 EST44920.1 - 0.00044 20.5 2.6 0.00044 20.5 2.6 2.8 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-C2H2_9 PF16293.5 EST44920.1 - 0.00065 19.5 9.8 5.9 6.8 0.0 4.9 3 2 2 5 5 5 0 C2H2 type zinc-finger (1 copy) BolA PF01722.18 EST44920.1 - 0.0023 18.2 2.8 0.81 10.0 0.0 3.4 2 1 1 3 3 3 1 BolA-like protein HypA PF01155.19 EST44920.1 - 0.0024 17.9 17.8 0.2 11.7 1.5 4.1 1 1 3 4 4 4 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-FCS PF06467.14 EST44920.1 - 0.0025 17.7 17.5 0.84 9.6 4.5 4.6 4 1 0 4 4 4 1 MYM-type Zinc finger with FCS sequence motif zf-C2H2_3rep PF18868.1 EST44920.1 - 0.0027 18.4 17.1 0.025 15.2 12.0 3.2 1 1 1 2 2 2 1 Zinc finger C2H2-type, 3 repeats DUF2340 PF10209.9 EST44920.1 - 0.0049 17.3 0.8 0.014 15.9 0.3 1.8 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2340) ADK_lid PF05191.14 EST44920.1 - 0.0063 16.5 7.6 1.2 9.2 0.1 3.7 3 1 1 4 4 4 1 Adenylate kinase, active site lid LIM PF00412.22 EST44920.1 - 0.0079 16.4 22.6 1.4 9.2 2.0 4.8 2 2 2 4 4 4 1 LIM domain HNH PF01844.23 EST44920.1 - 0.01 16.0 22.1 5.3 7.3 0.4 5.1 5 0 0 5 5 5 0 HNH endonuclease DZR PF12773.7 EST44920.1 - 0.011 15.8 16.1 7.1e+02 0.3 14.9 3.1 1 1 0 1 1 1 0 Double zinc ribbon GAGA PF09237.11 EST44920.1 - 0.011 15.5 2.2 0.82 9.5 0.3 2.6 1 1 1 2 2 2 0 GAGA factor zinc_ribbon_15 PF17032.5 EST44920.1 - 0.013 16.2 16.8 0.42 11.4 4.6 3.0 1 1 0 2 2 2 0 zinc-ribbon family HNH_5 PF14279.6 EST44920.1 - 0.021 14.7 17.4 0.25 11.2 3.6 4.2 4 0 0 4 4 4 0 HNH endonuclease zf_C2H2_ZHX PF18387.1 EST44920.1 - 0.035 13.8 2.2 0.035 13.8 2.2 4.7 4 1 1 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF3268 PF11672.8 EST44920.1 - 0.049 14.0 9.0 0.71 10.2 1.2 3.1 3 0 0 3 3 3 0 zinc-finger-containing domain zf-RRN7 PF11781.8 EST44920.1 - 0.053 13.2 13.8 2 8.2 0.2 5.0 5 0 0 5 5 5 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zinc_ribbon_4 PF13717.6 EST44920.1 - 0.073 13.0 17.3 8.7 6.4 0.1 5.1 4 1 0 4 4 4 0 zinc-ribbon domain Prok-RING_1 PF14446.6 EST44920.1 - 0.083 12.8 20.8 1.3 9.0 3.3 5.0 3 2 0 3 3 3 0 Prokaryotic RING finger family 1 Ta0938 PF11494.8 EST44920.1 - 0.094 13.0 0.1 0.094 13.0 0.1 3.2 1 1 2 3 3 3 0 Ta0938 STPPase_N PF16891.5 EST44920.1 - 0.14 12.6 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain DUF4524 PF15025.6 EST44920.1 - 0.21 11.3 3.8 0.25 11.1 1.5 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4524) zf_C2H2_10 PF18414.1 EST44920.1 - 0.26 10.9 5.4 3.5 7.3 0.0 3.8 3 0 0 3 3 3 0 C2H2 type zinc-finger YhfH PF14149.6 EST44920.1 - 0.26 11.3 13.4 16 5.6 0.3 4.5 4 0 0 4 4 4 0 YhfH-like protein zf-C2HC_2 PF13913.6 EST44920.1 - 0.26 11.2 0.2 0.26 11.2 0.2 5.1 5 1 0 5 5 5 0 zinc-finger of a C2HC-type zinc-ribbons_6 PF07191.12 EST44920.1 - 0.44 10.6 20.2 3.5 7.7 4.9 4.3 1 1 2 3 3 3 0 zinc-ribbons zinc_ribbon_9 PF14369.6 EST44920.1 - 0.47 10.7 0.1 0.47 10.7 0.1 4.7 6 0 0 6 6 5 0 zinc-ribbon zinc_ribbon_5 PF13719.6 EST44920.1 - 0.85 9.4 0.0 0.85 9.4 0.0 4.7 5 0 0 5 5 4 0 zinc-ribbon domain RNA_POL_M_15KD PF02150.16 EST44920.1 - 0.86 9.5 15.2 5.9 6.9 0.1 4.6 5 0 0 5 5 5 0 RNA polymerases M/15 Kd subunit Zn-C2H2_12 PF18112.1 EST44920.1 - 0.88 10.1 16.0 5.9 7.4 0.8 5.1 5 0 0 5 5 5 0 Autophagy receptor zinc finger-C2H2 domain zf-BED PF02892.15 EST44920.1 - 1 9.5 23.2 2.3 8.3 0.7 5.2 2 2 3 5 5 5 0 BED zinc finger DUF983 PF06170.12 EST44920.1 - 2.2 8.7 15.5 9.6 6.7 0.1 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF983) Terminase_GpA PF05876.12 EST44920.1 - 2.5 6.5 11.1 0.13 10.8 1.1 2.3 1 1 0 2 2 2 0 Phage terminase large subunit (GpA) TF_Zn_Ribbon PF08271.12 EST44920.1 - 4.9 6.8 20.7 2.2 7.8 3.0 4.5 3 2 0 3 3 3 0 TFIIB zinc-binding DUF2225 PF09986.9 EST44920.1 - 8.4 6.0 16.1 1.6 8.4 0.2 4.1 2 2 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) OrfB_Zn_ribbon PF07282.11 EST44920.1 - 9.9 6.2 21.0 4.1 7.4 3.2 4.6 1 1 4 5 5 5 0 Putative transposase DNA-binding domain ApoA-II PF04711.13 EST44921.1 - 0.22 11.7 1.5 1.4 9.1 0.1 2.9 4 0 0 4 4 4 0 Apolipoprotein A-II (ApoA-II) DUF3823_C PF18003.1 EST44922.1 - 0.043 14.5 0.2 0.046 14.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3823_C) Mfa_like_2 PF15415.6 EST44924.1 - 0.005 15.8 0.4 0.0092 14.9 0.4 1.4 1 0 0 1 1 1 1 Fimbrillin-like Alpha-amylase_C PF02806.18 EST44927.1 - 2.5e-12 47.1 0.4 2.3e-11 44.0 0.0 2.5 2 1 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 EST44927.1 - 1.1e-09 38.4 0.1 2.4e-06 27.4 0.0 2.5 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.18 EST44927.1 - 3.9e-06 27.1 1.1 1.8e-05 25.0 0.1 2.6 3 0 0 3 3 3 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) AMPK1_CBM PF16561.5 EST44927.1 - 0.017 15.3 2.4 0.061 13.5 1.0 2.6 2 1 0 2 2 2 0 Glycogen recognition site of AMP-activated protein kinase PPO1_DWL PF12142.8 EST44927.1 - 0.056 13.2 0.3 0.14 12.0 0.3 1.7 1 0 0 1 1 1 0 Polyphenol oxidase middle domain Ubiquitin_2 PF14560.6 EST44928.1 - 1.9e-20 73.1 0.0 3.7e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.25 EST44928.1 - 2.8e-17 62.5 0.0 4.3e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain ubiquitin PF00240.23 EST44928.1 - 0.0011 18.6 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family AAA_6 PF12774.7 EST44929.1 - 3.5e-82 276.0 0.0 3.5e-82 276.0 0.0 3.7 5 0 0 5 5 5 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EST44929.1 - 4e-40 138.1 20.4 4e-40 138.1 20.4 6.7 5 2 1 7 7 6 1 Dynein heavy chain, N-terminal region 2 MT PF12777.7 EST44929.1 - 6.3e-21 74.8 11.5 1.9e-20 73.2 11.5 1.8 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 EST44929.1 - 1.5e-17 63.8 0.0 1.4e-08 34.8 0.0 3.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_9 PF12781.7 EST44929.1 - 5.2e-12 45.4 6.0 5.2e-12 45.4 6.0 5.4 4 2 2 6 6 5 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 EST44929.1 - 3.2e-11 43.3 0.0 1.3e-10 41.4 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_7 PF12775.7 EST44929.1 - 8.1e-09 35.2 1.7 1.3e-05 24.8 0.0 3.8 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA PF00004.29 EST44929.1 - 0.00088 19.7 1.3 0.011 16.1 0.0 3.7 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EST44929.1 - 0.012 16.0 0.8 4.5 7.6 0.0 4.8 3 0 0 3 3 3 0 AAA ATPase domain Whirly PF08536.11 EST44929.1 - 0.056 13.3 0.6 0.21 11.4 0.1 2.2 2 0 0 2 2 2 0 Whirly transcription factor Alanine_zipper PF11839.8 EST44929.1 - 0.47 10.9 7.4 2.2 8.7 7.4 2.2 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein ABC_tran PF00005.27 EST44929.1 - 8.8 6.8 12.2 26 5.3 2.3 5.6 5 0 0 5 5 5 0 ABC transporter Baculo_FP PF03258.14 EST44930.1 - 0.1 12.8 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Baculovirus FP protein NopRA1 PF16201.5 EST44930.1 - 0.11 12.0 1.9 0.24 11.0 0.2 1.9 1 1 1 2 2 2 0 Nucleolar pre-ribosomal-associated protein 1 ARPC4 PF05856.12 EST44931.1 - 8.8e-07 28.7 4.0 1.5e-06 28.0 4.0 1.5 1 1 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Peptidase_C97 PF05903.14 EST44932.1 - 1.8e-24 86.3 0.1 3.2e-24 85.5 0.1 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain ARID PF01388.21 EST44934.1 - 1.7e-07 31.8 0.1 4.3e-07 30.5 0.1 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Lzipper-MIP1 PF14389.6 EST44938.1 - 0.056 13.7 0.1 0.1 12.9 0.1 1.5 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 FAM221 PF14753.6 EST44938.1 - 0.15 11.6 3.2 0.39 10.2 2.8 1.8 2 0 0 2 2 2 0 Protein FAM221A/B AAA_16 PF13191.6 EST44939.1 - 0.0028 18.1 0.0 0.0061 17.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EST44939.1 - 0.0082 15.9 0.1 0.036 13.8 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EST44939.1 - 0.0083 15.4 0.1 0.018 14.3 0.1 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_30 PF13604.6 EST44939.1 - 0.022 14.5 0.0 0.54 9.9 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EST44939.1 - 0.025 14.9 0.5 5.1 7.4 0.1 2.4 1 1 1 2 2 2 0 AAA domain AAA PF00004.29 EST44939.1 - 0.032 14.7 0.1 0.079 13.4 0.1 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 EST44939.1 - 0.059 13.1 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RsgA_GTPase PF03193.16 EST44939.1 - 0.084 12.8 0.1 0.24 11.3 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 EST44939.1 - 0.085 12.6 0.1 0.53 10.0 0.1 2.3 2 1 1 3 3 3 0 AAA domain Ank_2 PF12796.7 EST44940.1 - 1.8e-13 50.9 0.0 1.1e-08 35.5 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EST44940.1 - 8.7e-09 35.8 0.5 0.093 13.3 0.1 3.5 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EST44940.1 - 4.8e-05 23.4 0.1 1.5 9.6 0.0 4.4 3 1 1 4 4 4 1 Ankyrin repeat Ank PF00023.30 EST44940.1 - 0.0042 17.5 0.0 3.6 8.2 0.0 3.7 4 1 0 4 4 4 1 Ankyrin repeat UPF0242 PF06785.11 EST44942.1 - 1.4 9.0 5.3 0.2 11.7 0.7 1.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Ycf70 PF17382.2 EST44943.1 - 1.8 9.0 4.7 1.8 9.0 0.0 3.0 2 1 1 3 3 3 0 Uncharacterized Ycf70-like Myb_DNA-binding PF00249.31 EST44944.1 - 3.6e-08 33.5 0.1 0.0021 18.2 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST44944.1 - 5.3e-07 29.8 2.1 0.00051 20.2 0.5 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST44944.1 - 0.0067 16.3 2.1 0.11 12.4 0.0 2.7 2 1 1 3 3 3 1 Myb DNA-binding like DnaB_2 PF07261.11 EST44944.1 - 0.02 14.6 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Replication initiation and membrane attachment Myb_DNA-bind_4 PF13837.6 EST44944.1 - 0.14 12.5 1.6 2.7 8.5 0.3 2.9 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain Lectin_N PF03954.14 EST44945.1 - 0.13 12.0 3.1 1.9 8.2 0.7 2.5 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain AAA PF00004.29 EST44946.1 - 1.1e-37 129.4 0.0 2.3e-37 128.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EST44946.1 - 8e-10 38.5 0.1 1.4e-09 37.8 0.1 1.4 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EST44946.1 - 8.7e-09 35.0 0.1 1.9e-08 34.0 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EST44946.1 - 9.3e-06 25.9 0.0 2.6e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 EST44946.1 - 1.1e-05 24.8 0.0 2.4e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 EST44946.1 - 3.1e-05 24.0 0.3 0.00046 20.2 0.3 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EST44946.1 - 0.00021 21.8 0.2 0.001 19.5 0.1 2.4 2 1 0 2 2 1 1 AAA ATPase domain ATPase_2 PF01637.18 EST44946.1 - 0.0028 17.6 1.1 2.4 8.0 0.1 2.9 3 0 0 3 3 3 2 ATPase domain predominantly from Archaea RuvB_N PF05496.12 EST44946.1 - 0.0038 17.0 0.0 0.0093 15.7 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Parvo_NS1 PF01057.17 EST44946.1 - 0.0045 16.1 0.0 0.011 14.9 0.0 1.6 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_22 PF13401.6 EST44946.1 - 0.0089 16.3 0.0 0.67 10.2 0.0 3.1 1 1 2 3 3 3 1 AAA domain ABC_tran PF00005.27 EST44946.1 - 0.013 16.0 0.3 0.093 13.2 0.0 2.4 2 1 0 2 2 2 0 ABC transporter RNA_helicase PF00910.22 EST44946.1 - 0.013 15.9 0.0 0.04 14.3 0.0 1.9 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 EST44946.1 - 0.026 14.5 0.0 0.047 13.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMR_HSR1 PF01926.23 EST44946.1 - 0.03 14.4 0.1 3.2 7.8 0.0 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase ZapB PF06005.12 EST44946.1 - 0.059 13.8 0.2 0.17 12.3 0.2 1.8 1 0 0 1 1 1 0 Cell division protein ZapB AAA_29 PF13555.6 EST44946.1 - 0.059 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 EST44946.1 - 0.067 13.1 0.0 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 NTPase IstB_IS21 PF01695.17 EST44946.1 - 0.071 12.8 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 EST44946.1 - 0.072 12.6 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 EST44946.1 - 0.091 12.9 0.0 0.19 11.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EST44946.1 - 0.092 12.1 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RINT1_TIP1 PF04437.13 EST44946.1 - 0.095 11.6 2.2 0.14 11.1 2.2 1.2 1 0 0 1 1 1 0 RINT-1 / TIP-1 family AAA_14 PF13173.6 EST44946.1 - 0.11 12.5 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Occludin_ELL PF07303.13 EST44946.1 - 0.14 12.9 1.0 6.5 7.5 0.2 2.4 2 0 0 2 2 2 0 Occludin homology domain DUF3274 PF11678.8 EST44947.1 - 0.03 13.6 3.4 0.077 12.2 3.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3274) Pkinase PF00069.25 EST44948.1 - 9.9e-62 208.7 1.6 1.3e-61 208.3 1.6 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST44948.1 - 1.3e-34 119.6 0.4 2.1e-34 119.0 0.4 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EST44948.1 - 6.1e-10 38.9 0.1 9.7e-10 38.2 0.1 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EST44948.1 - 0.00098 18.5 0.3 0.0017 17.8 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EST44948.1 - 0.0017 17.2 0.0 0.0025 16.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase p25-alpha PF05517.12 EST44949.1 - 0.00023 21.3 0.5 0.09 12.9 0.2 2.3 1 1 1 2 2 2 2 p25-alpha ACDC PF14733.6 EST44949.1 - 3 8.2 6.1 3.5 8.0 4.7 1.7 1 1 1 2 2 2 0 AP2-coincident C-terminal DEAD PF00270.29 EST44950.1 - 1.6e-11 44.3 0.1 5.8e-11 42.5 0.1 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EST44950.1 - 1.3e-10 41.6 0.4 1.3e-10 41.6 0.4 3.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EST44950.1 - 6.8e-07 29.4 0.3 6.8e-07 29.4 0.3 3.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EST44950.1 - 0.00018 21.8 0.0 0.00092 19.5 0.0 2.2 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 EST44950.1 - 0.00023 21.2 0.0 0.0016 18.5 0.0 2.2 2 0 0 2 2 2 1 Flavivirus DEAD domain Helicase_RecD PF05127.14 EST44950.1 - 0.02 14.8 0.9 0.13 12.1 0.0 2.7 2 1 1 3 3 3 0 Helicase AAA_30 PF13604.6 EST44950.1 - 0.022 14.5 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Chordopox_A30L PF06015.12 EST44950.1 - 0.049 13.5 0.3 0.24 11.2 0.3 2.3 1 0 0 1 1 1 0 Chordopoxvirus A30L protein Imm59 PF15597.6 EST44950.1 - 1.8 9.1 8.4 9 6.8 0.6 4.0 3 0 0 3 3 3 0 Immunity protein 59 AsmA_1 PF13109.6 EST44951.1 - 0.006 16.1 1.2 0.0068 15.9 1.2 1.2 1 0 0 1 1 1 1 AsmA-like C-terminal region EF-hand_6 PF13405.6 EST44953.1 - 3.1e-08 32.9 5.6 3.1e-05 23.6 0.0 3.7 3 1 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 EST44953.1 - 5.6e-08 33.1 1.5 0.0018 18.7 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EST44953.1 - 5.8e-08 31.7 7.5 9.2e-05 21.7 0.0 4.8 5 1 1 6 6 6 2 EF hand EF-hand_5 PF13202.6 EST44953.1 - 7.7e-07 28.3 2.7 0.033 13.7 0.3 3.0 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 EST44953.1 - 0.0073 16.6 0.3 1.2 9.5 0.0 2.8 2 1 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 EST44953.1 - 0.015 15.2 7.7 0.22 11.4 0.2 4.0 2 2 2 5 5 5 0 EF-hand domain pair EF-hand_10 PF14788.6 EST44953.1 - 0.055 13.3 0.9 0.41 10.6 0.0 2.6 2 1 1 3 3 3 0 EF hand EF-hand_14 PF17959.1 EST44953.1 - 0.066 13.6 0.3 1.3 9.4 0.0 2.2 2 1 0 2 2 2 0 EF-hand domain Spidroin_MaSp PF11260.8 EST44953.1 - 0.1 12.9 0.0 0.65 10.3 0.0 2.0 2 0 0 2 2 2 0 Major ampullate spidroin 1 and 2 Radical_SAM PF04055.21 EST44954.1 - 7e-11 42.8 0.0 1.9e-10 41.4 0.0 1.7 1 1 1 2 2 2 1 Radical SAM superfamily BATS PF06968.13 EST44954.1 - 0.00023 21.2 0.0 0.00043 20.4 0.0 1.4 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Fucokinase PF07959.12 EST44955.1 - 0.057 12.4 0.0 0.062 12.2 0.0 1.1 1 0 0 1 1 1 0 L-fucokinase Copine PF07002.16 EST44956.1 - 3.4e-40 137.8 0.1 4.2e-40 137.5 0.1 1.1 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 EST44956.1 - 5.9e-16 59.2 0.0 9.5e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_3 PF13768.6 EST44956.1 - 0.0015 18.5 0.0 0.0044 17.0 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 EST44956.1 - 0.008 16.4 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Phage_lambda_P PF06992.11 EST44957.1 - 0.0076 16.0 0.5 0.0076 16.0 0.5 2.1 2 1 0 2 2 2 1 Replication protein P Aconitase_B_N PF11791.8 EST44957.1 - 0.047 13.8 2.7 0.078 13.1 1.9 1.9 1 1 0 1 1 1 0 Aconitate B N-terminal domain CDH1_2_SANT_HL1 PF18375.1 EST44957.1 - 0.23 12.2 6.9 1.3 9.8 0.4 2.6 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 DUF3499 PF12005.8 EST44957.1 - 2 9.0 6.0 12 6.5 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) Copine PF07002.16 EST44958.1 - 3e-38 131.5 0.1 3.8e-38 131.1 0.1 1.1 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 EST44958.1 - 1e-15 58.4 0.0 1.4e-15 57.9 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_3 PF13768.6 EST44958.1 - 0.0061 16.5 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EST44958.1 - 0.041 14.1 0.0 0.076 13.3 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain PI3_PI4_kinase PF00454.27 EST44960.1 - 6e-14 52.5 0.6 6e-14 52.5 0.6 3.5 4 0 0 4 4 4 1 Phosphatidylinositol 3- and 4-kinase HMG_box PF00505.19 EST44961.1 - 3.3e-10 40.2 7.9 1.2e-09 38.4 2.7 3.0 2 1 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EST44961.1 - 1.9e-08 34.8 0.4 1.9e-08 34.8 0.4 2.6 3 1 0 3 3 3 1 HMG-box domain CotJB PF12652.7 EST44962.1 - 6.7 7.0 8.9 0.95 9.7 0.5 3.9 3 0 0 3 3 3 0 CotJB protein Fer4_9 PF13187.6 EST44963.1 - 7.1e-09 35.7 23.1 3.6e-07 30.2 13.3 2.1 2 1 1 3 3 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 EST44963.1 - 1e-08 36.0 7.1 0.0007 20.5 0.5 2.6 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 EST44963.1 - 2.6e-07 30.6 11.8 5.5e-07 29.6 11.8 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 EST44963.1 - 4e-07 30.1 10.5 5.1e-05 23.3 0.5 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 EST44963.1 - 1.4e-06 27.9 3.8 1.4e-06 27.9 3.8 2.6 3 0 0 3 3 2 1 4Fe-4S binding domain Fer4_7 PF12838.7 EST44963.1 - 7.3e-06 26.5 14.5 0.00018 22.0 15.7 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 EST44963.1 - 8.9e-06 25.6 20.4 3.7e-05 23.6 4.6 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_15 PF13459.6 EST44963.1 - 1.9e-05 25.3 5.5 0.017 15.8 0.8 2.4 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_8 PF13183.6 EST44963.1 - 0.00011 22.6 11.3 0.00031 21.1 11.3 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 EST44963.1 - 0.00012 22.0 3.3 0.00012 22.0 3.3 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_17 PF13534.6 EST44963.1 - 0.0021 18.6 18.1 0.0037 17.8 14.9 2.8 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 EST44963.1 - 0.021 15.3 4.9 0.021 15.3 4.9 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 EST44963.1 - 0.058 14.2 8.5 0.48 11.3 0.1 3.0 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 EST44963.1 - 0.087 13.0 16.8 0.81 9.9 4.7 3.1 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 EST44963.1 - 1.1 9.8 19.8 6.2 7.5 18.6 2.6 2 1 0 2 2 1 0 4Fe-4S single cluster domain of Ferredoxin I DUF4381 PF14316.6 EST44964.1 - 0.0038 17.5 0.1 0.0046 17.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) PspB PF06667.12 EST44964.1 - 0.022 14.8 0.3 0.032 14.3 0.3 1.2 1 0 0 1 1 1 0 Phage shock protein B DUF2681 PF10883.8 EST44964.1 - 0.025 15.0 0.3 0.037 14.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) SNARE_assoc PF09335.11 EST44964.1 - 0.066 13.7 0.0 0.088 13.3 0.0 1.2 1 0 0 1 1 1 0 SNARE associated Golgi protein DUF2621 PF11084.8 EST44964.1 - 0.13 12.3 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) LRR_8 PF13855.6 EST44965.1 - 5.1 6.9 22.6 0.15 11.9 1.1 6.1 6 2 0 6 6 6 0 Leucine rich repeat CLASP_N PF12348.8 EST44966.1 - 8.5e-13 48.4 20.8 1.1e-06 28.3 9.2 3.6 3 1 0 3 3 3 3 CLASP N terminal HEAT PF02985.22 EST44966.1 - 0.00042 20.3 0.6 5.9 7.4 0.0 4.6 4 0 0 4 4 4 2 HEAT repeat Condensin2nSMC PF12422.8 EST44966.1 - 0.12 12.5 0.0 0.12 12.5 0.0 4.4 2 1 0 4 4 4 0 Condensin II non structural maintenance of chromosomes subunit Fer4_24 PF18109.1 EST44967.1 - 0.22 11.8 3.1 0.42 10.9 2.2 2.0 1 1 0 1 1 1 0 Ferredoxin I 4Fe-4S cluster domain Methyltransf_11 PF08241.12 EST44968.1 - 1.4e-15 57.7 0.0 2.7e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EST44968.1 - 1.4e-12 48.2 0.0 2.8e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EST44968.1 - 8.7e-11 41.9 0.0 1.1e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EST44968.1 - 4.4e-08 33.0 0.2 1e-07 31.8 0.2 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EST44968.1 - 1.1e-06 29.3 0.5 4.1e-06 27.4 0.1 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.15 EST44968.1 - 0.00021 21.2 0.0 0.00026 20.9 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Ubie_methyltran PF01209.18 EST44968.1 - 0.0025 17.2 0.0 0.034 13.5 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 EST44968.1 - 0.0058 15.2 0.0 0.0069 15.0 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_9 PF08003.11 EST44968.1 - 0.031 13.2 0.0 0.65 8.9 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) MetW PF07021.12 EST44968.1 - 0.075 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Phage_gp49_66 PF13876.6 EST44970.1 - 0.086 13.2 0.2 0.2 12.0 0.2 1.7 1 1 0 1 1 1 0 Phage protein (N4 Gp49/phage Sf6 gene 66) family DpnI PF06044.12 EST44972.1 - 0.00014 21.6 1.5 0.00023 20.9 1.3 1.4 1 1 0 1 1 1 1 Dam-replacing family DZR PF12773.7 EST44972.1 - 0.0024 17.8 2.1 0.0044 17.0 2.1 1.4 1 0 0 1 1 1 1 Double zinc ribbon zf-NADH-PPase PF09297.11 EST44972.1 - 0.0026 17.4 0.4 0.0052 16.4 0.4 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.6 EST44972.1 - 0.014 15.3 2.7 0.17 11.9 0.7 2.4 2 0 0 2 2 2 0 Nudix N-terminal zinc-ribbons_6 PF07191.12 EST44972.1 - 0.12 12.4 2.5 0.28 11.2 2.5 1.6 1 0 0 1 1 1 0 zinc-ribbons zf_UBZ PF18439.1 EST44972.1 - 0.13 11.8 3.1 6.1 6.5 0.1 2.7 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger C1_1 PF00130.22 EST44972.1 - 0.27 11.2 4.4 0.69 9.8 4.5 1.7 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_2 PF13240.6 EST44972.1 - 0.52 10.1 3.0 1.4 8.7 0.6 2.3 2 0 0 2 2 2 0 zinc-ribbon domain eIF-5_eIF-2B PF01873.17 EST44972.1 - 3.6 7.5 11.5 0.29 11.0 2.6 2.5 3 0 0 3 3 3 0 Domain found in IF2B/IF5 NOB1_Zn_bind PF08772.11 EST44972.1 - 7.7 6.8 7.4 5.2 7.3 2.3 2.5 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like HrpA_pilin PF09589.10 EST44973.1 - 0.037 14.7 0.6 0.037 14.7 0.6 2.3 2 1 0 2 2 2 0 HrpA pilus formation protein Amidase_6 PF12671.7 EST44973.1 - 0.04 14.0 0.4 0.04 14.0 0.4 1.8 2 0 0 2 2 2 0 Putative amidase domain A2M PF00207.22 EST44973.1 - 0.1 12.5 0.1 0.41 10.5 0.1 1.9 2 0 0 2 2 2 0 Alpha-2-macroglobulin family DUF4954 PF16314.5 EST44976.1 - 0.0036 15.5 2.6 0.026 12.7 2.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 EST44976.1 - 0.0045 16.0 0.4 0.0062 15.5 0.4 1.2 1 0 0 1 1 1 1 L-fucokinase Integrin_beta PF00362.18 EST44976.1 - 0.01 15.5 2.0 0.28 10.8 0.2 2.1 2 0 0 2 2 2 0 Integrin beta chain VWA domain GxGYxYP_N PF16216.5 EST44976.1 - 0.069 13.3 0.2 0.12 12.6 0.2 1.3 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function N-terminal Hexapep PF00132.24 EST44976.1 - 0.18 11.6 3.9 0.14 12.0 1.3 2.2 2 1 0 2 2 2 0 Bacterial transferase hexapeptide (six repeats) zf-HC5HC2H PF13771.6 EST44978.1 - 4e-10 39.8 8.3 1.1e-09 38.4 3.9 3.1 3 0 0 3 3 3 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EST44978.1 - 3.8e-07 30.2 4.7 3.8e-07 30.2 4.7 2.3 2 1 1 3 3 3 1 PHD-zinc-finger like domain H_lectin PF09458.10 EST44979.1 - 2 8.7 11.0 0.29 11.3 0.4 4.0 4 0 0 4 4 4 0 H-type lectin domain PGM_PMM_III PF02880.16 EST44980.1 - 7.9e-21 74.4 0.4 1.6e-20 73.4 0.4 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_I PF02878.16 EST44980.1 - 1.2e-14 54.2 0.0 3.4e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 EST44980.1 - 3.4e-12 46.9 0.0 1e-11 45.4 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EST44980.1 - 6.3e-09 35.9 0.0 1.5e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain HEAT PF02985.22 EST44981.1 - 2.7e-08 33.4 1.2 0.88 10.0 0.0 5.3 5 0 0 5 5 5 3 HEAT repeat Cnd1 PF12717.7 EST44981.1 - 0.00081 19.5 7.3 0.03 14.3 2.8 3.9 2 1 2 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EST44981.1 - 0.0012 19.2 0.0 2 8.9 0.0 2.5 1 1 1 2 2 2 2 HEAT repeats CENP-F_leu_zip PF10473.9 EST44982.1 - 0.022 14.8 3.1 0.18 11.8 0.2 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Occludin_ELL PF07303.13 EST44982.1 - 0.052 14.3 3.1 1.9 9.3 0.4 2.6 2 1 0 2 2 2 0 Occludin homology domain NPV_P10 PF05531.12 EST44982.1 - 0.055 13.9 11.1 0.17 12.3 0.1 3.4 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein MetOD2 PF18548.1 EST44982.1 - 0.17 12.0 2.0 0.27 11.4 0.2 2.2 2 1 1 3 3 3 0 Metanogen output domain 2 ATP-grasp_5 PF13549.6 EST44983.1 - 9.1e-39 133.2 0.0 1.4e-38 132.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 EST44983.1 - 6.4e-25 87.6 0.0 9.8e-16 57.8 0.0 2.5 2 0 0 2 2 2 2 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EST44983.1 - 1e-07 32.4 0.0 3.6e-07 30.7 0.0 2.0 1 0 0 1 1 1 1 CoA binding domain Trm5_N PF18093.1 EST44984.1 - 0.013 15.3 0.1 2.5 8.1 0.1 2.8 2 0 0 2 2 2 0 tRNA methyltransferase 5 N-terminal domain FlaF PF07309.11 EST44984.1 - 0.063 13.3 0.8 0.41 10.7 0.1 2.4 2 0 0 2 2 2 0 Flagellar protein FlaF Copine PF07002.16 EST44986.1 - 7.7e-38 130.1 0.1 9.5e-38 129.8 0.1 1.1 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 EST44986.1 - 4.4e-17 62.9 0.0 6.1e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_3 PF13768.6 EST44986.1 - 0.021 14.8 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain VWA PF00092.28 EST44986.1 - 0.04 14.2 0.0 0.074 13.3 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain DUF1830 PF08865.11 EST44987.1 - 0.0095 15.9 0.1 0.028 14.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1830) DUF5321 PF17254.2 EST44987.1 - 0.099 12.1 4.0 0.29 10.5 0.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5321) TRA-1_regulated PF02343.16 EST44987.1 - 0.22 11.6 6.5 0.056 13.5 3.2 1.6 2 0 0 2 2 2 0 TRA-1 regulated protein R03H10.4 Myb_DNA-bind_4 PF13837.6 EST44987.1 - 0.45 10.9 4.3 14 6.2 0.2 2.4 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF3847 PF12958.7 EST44988.1 - 7.6 6.7 6.9 21 5.3 1.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3847) RNA_pol_Rpb8 PF03870.15 EST44989.1 - 1.7e-19 70.4 0.1 1.9e-19 70.3 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 EST44989.1 - 0.012 15.7 0.6 0.018 15.1 0.3 1.6 1 1 1 2 2 2 0 DNA-directed RNA polymerase, subunit G Myb_DNA-binding PF00249.31 EST44990.1 - 3.6e-08 33.5 0.3 5.2e-08 32.9 0.3 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST44990.1 - 0.0012 19.1 0.3 0.0018 18.5 0.2 1.4 1 1 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EST44990.1 - 0.013 15.7 0.2 0.022 14.9 0.2 1.5 1 1 0 1 1 1 0 SANT/Myb-like domain of DAMP1 POB3_N PF17292.2 EST44990.1 - 0.12 12.8 0.6 0.22 11.9 0.3 1.6 1 1 0 1 1 1 0 POB3-like N-terminal PH domain IQ PF00612.27 EST44992.1 - 0.18 11.7 2.7 15 5.7 0.0 3.4 3 0 0 3 3 3 0 IQ calmodulin-binding motif tRNA-synt_2 PF00152.20 EST44993.1 - 1.1e-67 228.3 0.3 1.6e-67 227.9 0.3 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EST44993.1 - 5.5e-11 42.3 0.0 4.3e-10 39.4 0.0 2.2 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EST44993.1 - 1.7e-06 27.7 0.1 0.0023 17.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DUF4982 PF16355.5 EST44993.1 - 0.076 13.0 0.1 20 5.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4982) Flavodoxin_1 PF00258.25 EST44994.1 - 0.00073 19.8 0.0 0.0011 19.2 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin Lactamase_B_2 PF12706.7 EST44994.1 - 0.0031 17.1 0.0 0.0052 16.3 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Flavodoxin_5 PF12724.7 EST44994.1 - 0.015 15.5 0.0 0.026 14.8 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin domain DUF1972 PF09314.11 EST44994.1 - 0.066 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1972) PGM_PMM_I PF02878.16 EST44994.1 - 0.081 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I Rossmann-like PF10727.9 EST44994.1 - 0.16 11.9 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 Rossmann-like domain Nucleoporin2 PF04096.14 EST44995.1 - 2.5e-18 66.6 0.1 7.6e-18 65.0 0.1 1.8 1 0 0 1 1 1 1 Nucleoporin autopeptidase IZUMO PF15005.6 EST44995.1 - 0.18 12.3 2.2 0.31 11.6 0.8 2.1 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Arrestin_C PF02752.22 EST44996.1 - 0.047 14.2 4.2 0.22 11.9 0.3 2.3 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain LRR_4 PF12799.7 EST44996.1 - 0.16 12.5 49.2 0.087 13.3 6.4 6.6 2 1 5 7 7 7 0 Leucine Rich repeats (2 copies) Pentapeptide_4 PF13599.6 EST44996.1 - 3.3 8.0 10.3 0.77 10.0 3.2 3.3 3 0 0 3 3 3 0 Pentapeptide repeats (9 copies) MIF4G_like PF09088.11 EST44997.1 - 0.058 13.2 0.5 0.1 12.3 0.2 1.6 2 0 0 2 2 2 0 MIF4G like zf-RING_2 PF13639.6 EST44999.1 - 1.7e-08 34.7 2.9 1.7e-08 34.7 2.9 2.8 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.7 EST44999.1 - 1.1e-06 28.8 7.4 1.1e-06 28.8 7.4 2.4 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EST44999.1 - 5.1e-06 26.2 2.2 5.1e-06 26.2 2.2 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EST44999.1 - 1.6e-05 24.7 11.7 0.00039 20.2 7.8 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EST44999.1 - 2.9e-05 24.0 0.6 2.9e-05 24.0 0.6 1.8 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EST44999.1 - 0.00074 19.4 1.3 0.00074 19.4 1.3 2.6 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EST44999.1 - 0.001 18.9 1.1 0.001 18.9 1.1 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EST44999.1 - 0.0017 18.2 4.4 0.0019 18.0 2.2 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 EST44999.1 - 0.006 16.3 1.3 0.006 16.3 1.3 2.5 2 0 0 2 2 2 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 EST44999.1 - 0.0076 15.9 4.7 0.0079 15.8 1.8 2.3 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 EST44999.1 - 0.013 15.5 6.1 0.013 15.5 6.1 2.5 3 1 0 3 3 1 0 RING-type zinc-finger RINGv PF12906.7 EST44999.1 - 0.015 15.4 2.4 0.015 15.4 2.4 2.3 3 0 0 3 3 2 0 RING-variant domain DUF5447 PF17525.2 EST44999.1 - 0.074 13.5 4.0 0.18 12.3 4.0 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5447) DUF4974 PF16344.5 EST44999.1 - 0.078 13.0 2.3 1.8 8.6 0.7 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4974) ComJ PF11033.8 EST44999.1 - 0.11 12.2 0.0 18 5.1 0.0 2.4 2 0 0 2 2 2 0 Competence protein J (ComJ) zf-C3H2C3 PF17122.5 EST44999.1 - 0.11 12.5 6.3 0.46 10.6 6.3 2.1 1 1 0 1 1 1 0 Zinc-finger zf-Nse PF11789.8 EST44999.1 - 0.44 10.4 3.2 0.22 11.4 0.8 1.8 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 EST44999.1 - 0.49 10.6 9.0 1.6 8.9 5.1 3.1 2 1 0 2 2 2 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 EST44999.1 - 4.4 7.5 7.7 0.61 10.3 3.0 2.0 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING Pkinase PF00069.25 EST45000.1 - 5.7e-59 199.6 0.2 7e-59 199.3 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST45000.1 - 1.7e-40 138.9 0.1 2.1e-40 138.6 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EST45000.1 - 1.5e-08 34.3 0.0 6.6e-05 22.4 0.0 2.2 1 1 1 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EST45000.1 - 6.2e-06 25.2 0.1 8.8e-06 24.7 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EST45000.1 - 0.0064 16.4 0.0 0.062 13.2 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 EST45000.1 - 0.034 13.8 0.3 2.3 7.8 0.1 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Rib_hydrolayse PF02267.17 EST45000.1 - 0.035 13.5 0.0 0.095 12.1 0.0 1.7 2 0 0 2 2 2 0 ADP-ribosyl cyclase Ipi1_N PF12333.8 EST45001.1 - 0.91 10.1 3.3 1.1 9.9 0.0 2.8 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation BBS2_Mid PF14783.6 EST45002.1 - 0.027 14.5 0.2 9.2 6.4 0.1 3.3 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region zf-RING_2 PF13639.6 EST45003.1 - 1.4e-07 31.7 10.9 3e-07 30.7 10.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EST45003.1 - 1.5e-05 24.7 11.3 3.5e-05 23.6 11.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EST45003.1 - 3.3e-05 23.6 8.6 6.1e-05 22.8 8.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EST45003.1 - 0.00029 20.6 12.0 0.00056 19.7 12.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EST45003.1 - 0.00036 20.4 8.7 0.0008 19.3 8.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 EST45003.1 - 0.0064 16.3 7.4 0.017 14.9 7.4 1.7 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain DUF4478 PF14793.6 EST45003.1 - 0.018 14.9 0.0 0.068 13.0 0.0 2.0 1 0 0 1 1 1 0 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases zf-ANAPC11 PF12861.7 EST45003.1 - 0.06 13.4 4.4 0.1 12.6 4.4 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 EST45003.1 - 0.77 10.1 8.3 1.6 9.1 8.3 1.6 1 0 0 1 1 1 0 RING-like domain zf-RING_UBOX PF13445.6 EST45003.1 - 0.78 9.8 8.2 8.2 6.5 8.8 2.3 1 1 1 2 2 2 0 RING-type zinc-finger zf-rbx1 PF12678.7 EST45003.1 - 1.8 8.9 12.1 8.2 6.8 12.1 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EST45003.1 - 5.8 6.9 11.6 86 3.1 11.8 2.3 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_5 PF17121.5 EST45003.1 - 7.8 6.5 8.3 25 4.9 8.3 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CC2-LZ PF16516.5 EST45003.1 - 9.9 6.6 22.8 0.62 10.5 5.7 3.7 1 1 3 4 4 4 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator EF-hand_like PF09279.11 EST45005.1 - 0.0029 18.1 1.2 0.023 15.2 0.0 3.0 3 0 0 3 3 3 1 Phosphoinositide-specific phospholipase C, efhand-like AlphaC_N PF08829.10 EST45005.1 - 0.026 14.6 0.1 0.095 12.7 0.1 2.0 1 0 0 1 1 1 0 Alpha C protein N terminal DUF4497 PF14924.6 EST45005.1 - 0.084 13.4 0.5 5.4 7.5 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) LRR_4 PF12799.7 EST45008.1 - 0.00033 21.0 1.2 0.00033 21.0 1.2 5.8 1 1 5 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EST45008.1 - 0.00033 20.3 26.6 0.00068 19.4 1.2 5.9 4 2 1 5 5 5 2 Leucine rich repeat MA-Mit PF09245.10 EST45008.1 - 0.00064 19.3 0.9 0.00064 19.3 0.9 2.0 2 0 0 2 2 2 1 Mycoplasma arthritidis-derived mitogen LRR_6 PF13516.6 EST45008.1 - 0.039 14.0 12.3 1.8 8.8 0.0 6.2 7 0 0 7 7 7 0 Leucine Rich repeat Ycf34 PF10718.9 EST45009.1 - 0.29 11.9 3.8 24 5.7 1.6 4.0 2 0 0 2 2 2 0 Hypothetical chloroplast protein Ycf34 IF4E PF01652.18 EST45011.1 - 4.6e-14 52.5 0.0 5.3e-14 52.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DEAD_2 PF06733.15 EST45012.1 - 1.4e-21 76.9 12.9 1.4e-21 76.9 12.9 2.0 2 0 0 2 2 2 1 DEAD_2 Helicase_C_2 PF13307.6 EST45012.1 - 1.5e-20 74.0 1.2 5.2e-20 72.3 1.2 1.9 1 0 0 1 1 1 1 Helicase C-terminal domain AAA_11 PF13086.6 EST45012.1 - 0.23 11.2 4.7 0.039 13.7 0.9 1.6 2 0 0 2 2 2 0 AAA domain IF4E PF01652.18 EST45013.1 - 1.3e-05 25.0 0.1 1.4e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E zf-C2H2_jaz PF12171.8 EST45015.1 - 3.2e-06 27.3 5.2 3.2e-06 27.3 5.2 1.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EST45015.1 - 0.00045 20.5 3.1 0.00073 19.8 3.1 1.4 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) DUF4187 PF13821.6 EST45015.1 - 0.0089 15.8 0.1 0.026 14.3 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) zf-C2H2_4 PF13894.6 EST45015.1 - 0.023 15.5 0.7 0.068 14.0 0.7 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger Elongin_A PF06881.11 EST45015.1 - 0.023 15.2 0.0 0.036 14.6 0.0 1.3 1 1 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A zf-met PF12874.7 EST45015.1 - 0.2 12.1 2.5 0.44 11.0 2.5 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-U1 PF06220.12 EST45015.1 - 4.5 7.1 8.4 5.5 6.8 3.2 2.4 2 0 0 2 2 2 0 U1 zinc finger IKKbetaNEMObind PF12179.8 EST45017.1 - 0.088 12.9 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain DUF5533 PF17685.1 EST45018.1 - 0.049 14.0 0.0 0.087 13.2 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5533) Cyt-b5 PF00173.28 EST45019.1 - 7.7e-06 26.0 0.0 1.1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ras PF00071.22 EST45020.1 - 1.6e-35 122.1 0.1 2.2e-35 121.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EST45020.1 - 2.5e-28 98.7 0.1 5.7e-28 97.5 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EST45020.1 - 1.1e-11 44.5 0.0 1.5e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EST45020.1 - 3.3e-08 33.6 0.0 8.2e-08 32.3 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EST45020.1 - 2.8e-07 30.1 0.2 3.9e-07 29.7 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EST45020.1 - 0.0018 17.5 0.2 0.058 12.5 0.0 2.3 1 1 1 2 2 2 1 G-protein alpha subunit Dynamin_N PF00350.23 EST45020.1 - 0.021 14.9 0.0 0.91 9.6 0.0 2.7 3 0 0 3 3 3 0 Dynamin family TniB PF05621.11 EST45020.1 - 0.055 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_7 PF12775.7 EST45020.1 - 0.067 12.7 0.2 0.38 10.3 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region Ldh_1_N PF00056.23 EST45020.1 - 0.11 12.6 0.0 14 5.7 0.0 2.6 3 0 0 3 3 3 0 lactate/malate dehydrogenase, NAD binding domain Microtub_bd PF16796.5 EST45021.1 - 0.12 12.3 11.2 0.13 12.2 0.2 3.5 2 1 0 2 2 2 0 Microtubule binding D5_N PF08706.11 EST45022.1 - 0.3 11.3 3.2 0.64 10.3 3.2 1.9 1 1 0 1 1 1 0 D5 N terminal like MIF PF01187.18 EST45023.1 - 0.0065 16.8 0.0 0.0073 16.6 0.0 1.1 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) zf-met PF12874.7 EST45024.1 - 1.4e-09 38.0 4.7 7.8e-07 29.3 0.2 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EST45024.1 - 1.6e-09 37.8 3.4 1.3e-05 25.4 0.1 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EST45024.1 - 1.5e-06 28.4 4.4 0.0012 19.1 0.8 2.2 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EST45024.1 - 0.0022 18.7 7.5 0.28 12.1 0.0 3.6 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EST45024.1 - 0.2 12.2 11.1 0.5 10.9 0.2 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-LYAR PF08790.11 EST45024.1 - 0.34 10.9 0.0 0.34 10.9 0.0 3.1 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-C2H2_jaz PF12171.8 EST45025.1 - 1.8e-08 34.4 8.4 1.7e-05 25.0 2.3 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EST45025.1 - 4.3e-08 33.3 6.1 1.8e-06 28.1 1.2 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EST45025.1 - 0.00025 21.3 8.8 0.032 14.5 9.5 2.1 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EST45025.1 - 0.0023 18.6 7.7 0.66 11.0 1.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_3 PF13878.6 EST45025.1 - 0.0077 16.0 0.6 4.5 7.2 0.2 2.5 2 0 0 2 2 2 2 zinc-finger of acetyl-transferase ESCO zf-C2H2 PF00096.26 EST45025.1 - 0.016 15.6 8.0 0.059 13.8 1.1 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type Lar_restr_allev PF14354.6 EST45025.1 - 0.27 11.6 1.5 3.9 7.9 1.8 2.2 1 1 1 2 2 2 0 Restriction alleviation protein Lar zf-trcl PF13451.6 EST45025.1 - 0.34 10.8 3.2 13 5.8 0.4 2.3 2 0 0 2 2 2 0 Probable zinc-ribbon domain zf-H2C2_2 PF13465.6 EST45025.1 - 1.8 9.1 0.1 1.8 9.1 0.1 3.1 4 0 0 4 4 4 0 Zinc-finger double domain ThiF PF00899.21 EST45026.1 - 5e-10 39.1 0.0 5.5e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 ThiF family DUF1192 PF06698.11 EST45027.1 - 0.94 9.6 5.9 3.6 7.7 0.1 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1192) KH_5 PF13184.6 EST45027.1 - 2.4 8.3 7.3 20 5.4 0.2 3.6 2 1 0 2 2 2 0 NusA-like KH domain AlbA_2 PF04326.14 EST45028.1 - 6e-15 55.7 0.0 2.4e-14 53.7 0.0 2.1 2 0 0 2 2 2 1 Putative DNA-binding domain AAA_16 PF13191.6 EST45028.1 - 0.00025 21.4 0.0 0.00061 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Tau95 PF09734.9 EST45028.1 - 0.12 13.2 0.1 0.37 11.6 0.0 1.8 2 0 0 2 2 2 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain DUF4472 PF14739.6 EST45030.1 - 0.003 18.3 3.2 0.003 18.3 3.2 7.3 5 1 2 8 8 8 2 Domain of unknown function (DUF4472) AT_hook PF02178.19 EST45032.1 - 0.01 15.6 0.6 0.026 14.3 0.6 1.7 1 0 0 1 1 1 0 AT hook motif DUF846 PF05832.12 EST45033.1 - 0.41 10.7 5.8 0.15 12.1 2.7 1.9 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF846) Peptidase_C48 PF02902.19 EST45034.1 - 3.2e-10 40.2 4.6 1.8e-06 27.9 0.6 2.6 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain AvrB_AvrC PF05394.11 EST45034.1 - 0.12 11.6 0.7 0.19 10.9 0.7 1.3 1 0 0 1 1 1 0 Avirulence protein WD40 PF00400.32 EST45035.1 - 3.1e-13 49.9 0.0 1.8e-05 25.4 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EST45035.1 - 2.1e-08 34.4 0.3 0.051 13.9 0.1 3.7 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EST45035.1 - 8.7e-07 29.0 0.3 0.00063 19.7 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Clr2_transil PF16761.5 EST45035.1 - 0.18 12.7 0.9 0.41 11.5 0.2 2.0 2 0 0 2 2 2 0 Transcription-silencing protein, cryptic loci regulator Clr2 MerR_1 PF13411.6 EST45036.1 - 0.03 14.4 3.5 0.81 9.8 0.1 2.4 2 0 0 2 2 2 0 MerR HTH family regulatory protein Snf7 PF03357.21 EST45036.1 - 0.053 13.1 14.2 0.097 12.3 14.2 1.5 1 1 0 1 1 1 0 Snf7 IMS PF00817.20 EST45036.1 - 0.16 11.9 1.4 0.37 10.8 0.3 1.8 1 1 0 2 2 2 0 impB/mucB/samB family DUF4402 PF14352.6 EST45037.1 - 0.035 14.7 0.8 0.071 13.8 0.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4402) DIL PF01843.19 EST45040.1 - 1.7 8.9 11.0 1.1 9.5 6.2 3.0 2 2 0 2 2 2 0 DIL domain TEBP_beta PF07404.11 EST45040.1 - 2.8 7.2 6.9 0.46 9.8 0.5 2.1 2 0 0 2 2 2 0 Telomere-binding protein beta subunit (TEBP beta) DUF948 PF06103.11 EST45041.1 - 0.76 10.1 8.1 28 5.1 2.6 3.5 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Fzo_mitofusin PF04799.13 EST45041.1 - 6.7 6.2 10.5 3 7.4 2.9 2.6 1 1 1 2 2 2 0 fzo-like conserved region Thioredoxin PF00085.20 EST45043.1 - 2.6e-09 37.0 0.1 3e-09 36.8 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EST45043.1 - 0.01 16.1 0.3 0.13 12.6 0.2 2.1 1 1 1 2 2 2 0 Thioredoxin-like PHD PF00628.29 EST45044.1 - 1.2e-05 25.1 5.0 1.2e-05 25.1 5.0 4.1 5 1 0 5 5 5 1 PHD-finger zf-RING_2 PF13639.6 EST45044.1 - 4.8e-05 23.6 4.7 4.8e-05 23.6 4.7 4.9 5 1 0 5 5 5 1 Ring finger domain zf-ANAPC11 PF12861.7 EST45044.1 - 0.016 15.2 2.2 0.016 15.2 2.2 3.1 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger ATP_transf PF09830.9 EST45046.1 - 0.0013 18.8 0.0 0.0025 17.9 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4922 PF16269.5 EST45046.1 - 0.0033 17.2 0.0 0.007 16.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4922) RNA_pol_RpbG PF16992.5 EST45046.1 - 0.0099 15.9 0.0 0.031 14.3 0.0 1.8 1 0 0 1 1 1 1 DNA-directed RNA polymerase, subunit G Metallophos PF00149.28 EST45047.1 - 1.7e-36 126.6 0.0 2.2e-36 126.3 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EST45047.1 - 5.7e-14 52.3 0.1 1.1e-13 51.4 0.1 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain AAA_13 PF13166.6 EST45048.1 - 0.00029 19.6 15.9 0.00038 19.2 15.9 1.1 1 0 0 1 1 1 1 AAA domain Leu_zip PF15294.6 EST45048.1 - 0.014 15.0 18.9 0.38 10.2 13.8 2.2 2 0 0 2 2 2 0 Leucine zipper CLZ PF16526.5 EST45048.1 - 0.031 14.6 2.5 0.031 14.6 2.5 4.2 2 1 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ABC_tran_CTD PF16326.5 EST45048.1 - 0.047 13.9 26.8 0.031 14.5 10.9 3.9 2 2 2 4 4 4 0 ABC transporter C-terminal domain Dermcidin PF15291.6 EST45048.1 - 0.15 12.6 0.0 0.35 11.4 0.0 1.6 1 1 0 1 1 1 0 Dermcidin, antibiotic peptide DUF5365 PF17326.2 EST45048.1 - 0.19 12.1 6.8 0.095 13.1 3.7 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5365) COQ9 PF08511.11 EST45048.1 - 0.31 10.8 1.5 0.64 9.8 0.2 2.1 2 1 1 3 3 3 0 COQ9 DUF4988 PF16378.5 EST45048.1 - 0.48 10.1 10.9 0.68 9.6 0.1 3.6 4 1 0 4 4 4 0 Domain of unknown function MscS_porin PF12795.7 EST45048.1 - 1.5 8.4 32.8 42 3.6 33.2 2.2 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain Mod_r PF07200.13 EST45048.1 - 1.8 8.6 27.5 0.088 12.9 1.7 2.6 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein TMF_TATA_bd PF12325.8 EST45048.1 - 2 8.7 26.8 3.1 8.0 1.5 3.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding FlaC_arch PF05377.11 EST45048.1 - 2.9 8.3 16.0 1.5 9.3 1.5 4.0 3 2 0 3 3 3 0 Flagella accessory protein C (FlaC) TPR_MLP1_2 PF07926.12 EST45048.1 - 3.2 7.8 29.7 4.3 7.4 4.2 3.3 2 2 1 3 3 3 0 TPR/MLP1/MLP2-like protein BST2 PF16716.5 EST45048.1 - 5.4 7.7 27.3 11 6.7 13.9 3.3 2 1 0 2 2 2 0 Bone marrow stromal antigen 2 CENP-F_leu_zip PF10473.9 EST45048.1 - 5.6 7.0 31.5 2.7 8.0 5.7 3.3 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.7 EST45048.1 - 6.4 6.9 32.8 1.4 9.0 18.4 2.7 1 1 2 3 3 3 0 Tropomyosin like Atg14 PF10186.9 EST45048.1 - 8.1 5.4 22.7 2.8 7.0 6.9 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 SIKE PF05769.11 EST45048.1 - 8.6 6.2 26.4 2.6e+02 1.4 26.4 2.2 1 1 0 1 1 1 0 SIKE family ATG16 PF08614.11 EST45048.1 - 8.9 6.5 27.9 10 6.3 6.4 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF4201 PF13870.6 EST45049.1 - 5.6e-11 42.5 34.8 1.7e-10 40.9 32.8 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4201) FAM76 PF16046.5 EST45049.1 - 6.2 6.1 21.7 0.44 9.9 15.2 1.9 2 0 0 2 2 2 0 FAM76 protein Tli4_N PF18443.1 EST45049.1 - 9.8 6.5 9.1 1.1 9.7 2.7 2.5 1 1 0 2 2 2 0 Tle cognate immunity protein 4 N-terminal domain Spermine_synth PF01564.17 EST45050.1 - 0.11 11.9 0.1 0.13 11.7 0.1 1.1 1 0 0 1 1 1 0 Spermine/spermidine synthase domain Snf7 PF03357.21 EST45051.1 - 0.0011 18.6 15.5 0.0011 18.6 15.5 1.8 1 1 1 2 2 2 2 Snf7 NYD-SP28_assoc PF14775.6 EST45051.1 - 0.3 11.2 6.2 0.76 9.9 1.6 2.7 2 0 0 2 2 2 0 Sperm tail C-terminal domain SlyX PF04102.12 EST45051.1 - 0.48 11.1 18.2 1.2 9.7 2.0 4.2 4 0 0 4 4 4 0 SlyX MCM PF00493.23 EST45052.1 - 1.4e-73 246.7 0.1 2.4e-73 246.0 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 EST45052.1 - 5.7e-17 61.9 0.1 1.2e-16 60.9 0.1 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EST45052.1 - 8e-13 48.9 1.4 3.5e-12 46.8 1.4 2.2 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EST45052.1 - 1.3e-09 37.8 0.9 2.1e-07 30.6 0.1 3.2 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI MCM_OB PF17207.3 EST45052.1 - 1.1e-08 34.9 0.6 4.1e-08 33.1 0.6 2.0 1 1 0 1 1 1 1 MCM OB domain AAA_5 PF07728.14 EST45052.1 - 3.9e-07 30.2 0.0 6e-06 26.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EST45052.1 - 8e-05 22.5 0.0 0.00022 21.1 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EST45052.1 - 0.0045 16.7 0.4 0.44 10.2 0.0 3.7 3 1 0 3 3 3 1 Sigma-54 interaction domain AAA PF00004.29 EST45052.1 - 0.042 14.3 0.3 0.16 12.4 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) HypA PF01155.19 EST45052.1 - 0.1 12.6 0.1 0.42 10.6 0.0 2.1 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA YchF-GTPase_C PF06071.13 EST45054.1 - 2.9e-36 123.5 0.6 6.6e-36 122.4 0.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EST45054.1 - 6.4e-18 64.9 0.0 1.6e-17 63.6 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EST45054.1 - 4.2e-05 23.1 0.7 0.00019 21.0 0.0 2.2 2 1 0 2 2 2 1 Ferrous iron transport protein B CSF-1 PF05337.11 EST45054.1 - 0.0011 19.1 1.2 0.14 12.3 0.2 2.5 2 0 0 2 2 2 2 Macrophage colony stimulating factor-1 (CSF-1) PglD_N PF17836.1 EST45054.1 - 0.055 14.1 0.5 21 5.8 0.2 3.2 2 1 1 3 3 3 0 PglD N-terminal domain C_GCAxxG_C_C PF09719.10 EST45055.1 - 0.029 14.7 0.9 0.75 10.1 0.9 2.1 1 1 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) Alpha-2-MRAP_N PF06400.11 EST45056.1 - 0.015 15.3 0.7 0.015 15.3 0.7 2.0 2 0 0 2 2 2 0 Alpha-2-macroglobulin RAP, N-terminal domain TMF_DNA_bd PF12329.8 EST45056.1 - 0.12 12.4 0.1 0.12 12.4 0.1 3.3 2 2 2 4 4 4 0 TATA element modulatory factor 1 DNA binding Metallophos PF00149.28 EST45057.1 - 9.7e-09 36.0 0.0 1.7e-08 35.2 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EST45057.1 - 9.9e-06 25.8 0.0 1.2e-05 25.6 0.0 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 EST45057.1 - 0.061 12.6 0.0 0.088 12.1 0.0 1.2 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily T2SSJ PF11612.8 EST45058.1 - 0.36 11.0 4.1 1 9.6 4.0 1.6 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein J CBM_20 PF00686.19 EST45059.1 - 0.0032 17.4 0.0 0.41 10.6 0.0 2.7 2 0 0 2 2 2 2 Starch binding domain Flp_N PF03930.14 EST45059.1 - 0.13 12.2 4.6 0.38 10.8 0.0 3.1 3 1 0 3 3 3 0 Recombinase Flp protein N-terminus LRR_9 PF14580.6 EST45060.1 - 4.1e-12 46.0 0.6 4.1e-12 46.0 0.6 2.2 1 1 0 2 2 2 1 Leucine-rich repeat Ribosomal_L22e PF01776.17 EST45060.1 - 0.013 15.8 5.0 0.013 15.8 5.0 2.4 2 1 0 2 2 2 0 Ribosomal L22e protein family LRR_4 PF12799.7 EST45060.1 - 0.043 14.3 0.6 0.21 12.1 0.6 2.3 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) DUF778 PF05608.12 EST45061.1 - 1.7e-17 64.4 2.3 8.3e-13 49.1 0.1 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF778) DUF4796 PF16044.5 EST45061.1 - 8.7e-07 28.7 0.1 1.2e-06 28.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4796) Peptidase_C97 PF05903.14 EST45061.1 - 0.00041 20.2 0.2 0.00051 19.9 0.2 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 EST45061.1 - 0.00057 20.2 0.0 0.0007 19.9 0.0 1.3 1 0 0 1 1 1 1 Lecithin retinol acyltransferase PAN_3 PF08277.12 EST45061.1 - 0.03 14.1 0.2 0.054 13.3 0.2 1.5 1 1 0 1 1 1 0 PAN-like domain DTW PF03942.15 EST45062.1 - 1.5e-13 50.9 0.5 2.3e-13 50.3 0.5 1.3 1 0 0 1 1 1 1 DTW domain zf-B_box PF00643.24 EST45062.1 - 0.01 15.9 0.7 0.02 15.0 0.7 1.5 1 0 0 1 1 1 0 B-box zinc finger IPK PF03770.16 EST45063.1 - 1.1e-12 48.2 1.9 3.9e-12 46.4 1.9 1.7 1 1 0 1 1 1 1 Inositol polyphosphate kinase TTL PF03133.15 EST45064.1 - 7.2e-69 232.1 5.8 9.4e-69 231.8 5.8 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EST45064.1 - 2.5e-11 43.3 0.6 9e-06 25.1 0.1 2.2 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EST45064.1 - 7e-08 32.1 0.1 0.0067 15.7 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp DUF3425 PF11905.8 EST45064.1 - 0.026 14.5 2.6 1.3 9.0 2.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3425) Oxysterol_BP PF01237.18 EST45065.1 - 5.3e-17 61.7 1.0 7.5e-08 31.6 0.0 2.1 1 1 0 2 2 2 2 Oxysterol-binding protein DUF4538 PF15061.6 EST45069.1 - 3.6 7.4 9.5 0.18 11.6 0.7 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4538) SLC35F PF06027.12 EST45070.1 - 6.8e-21 75.0 25.7 8e-21 74.8 25.7 1.0 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 EST45070.1 - 6.9e-12 45.7 37.4 3.8e-07 30.4 18.5 2.2 2 0 0 2 2 2 2 EamA-like transporter family DUF202 PF02656.15 EST45070.1 - 0.025 15.0 0.5 0.025 15.0 0.5 3.6 4 1 0 4 4 4 0 Domain of unknown function (DUF202) zf-DBF PF07535.12 EST45071.1 - 0.0026 17.8 0.8 0.0087 16.2 0.8 1.9 1 0 0 1 1 1 1 DBF zinc finger CCDC84 PF14968.6 EST45071.1 - 0.024 14.2 0.2 0.024 14.2 0.2 3.2 3 1 0 3 3 3 0 Coiled coil protein 84 Phasin_2 PF09361.10 EST45071.1 - 0.5 10.7 6.4 17 5.7 0.0 4.2 5 0 0 5 5 5 0 Phasin protein 2OG-Fe_Oxy_2 PF10014.9 EST45072.1 - 0.033 14.0 0.1 0.063 13.1 0.1 1.4 1 0 0 1 1 1 0 2OG-Fe dioxygenase DUF2661 PF10860.8 EST45072.1 - 2.1 8.5 6.4 1.8 8.7 1.9 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2661) REF PF05755.12 EST45073.1 - 0.053 13.3 0.1 0.057 13.2 0.1 1.0 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) CoaE PF01121.20 EST45075.1 - 1e-34 119.8 1.3 5e-33 114.3 1.3 2.0 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 EST45075.1 - 3.1e-05 24.5 0.3 0.00018 22.1 0.3 2.1 1 1 0 1 1 1 1 AAA domain tRNA_lig_kinase PF08303.11 EST45075.1 - 0.00044 20.4 4.8 0.0011 19.1 0.5 2.2 2 0 0 2 2 2 1 tRNA ligase kinase domain G-alpha PF00503.20 EST45075.1 - 0.00063 19.0 4.2 0.0016 17.7 4.2 1.8 1 1 0 1 1 1 1 G-protein alpha subunit AAA_17 PF13207.6 EST45075.1 - 0.00066 20.1 0.0 0.0086 16.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EST45075.1 - 0.0048 16.2 0.2 0.11 11.7 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin PduV-EutP PF10662.9 EST45075.1 - 0.0064 16.3 0.1 0.013 15.2 0.1 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 EST45075.1 - 0.0067 16.7 0.4 0.025 14.8 0.1 2.1 2 2 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EST45075.1 - 0.0071 16.7 0.0 0.012 16.0 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain PRK PF00485.18 EST45075.1 - 0.0085 15.8 0.0 2.1 8.0 0.0 2.3 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family DUF4479 PF14794.6 EST45075.1 - 0.014 15.3 0.3 0.17 11.7 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4479) AAA_28 PF13521.6 EST45075.1 - 0.015 15.6 0.0 0.038 14.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EST45075.1 - 0.018 15.2 0.0 0.046 13.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain Hpr_kinase_C PF07475.12 EST45075.1 - 0.022 14.3 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain Cytidylate_kin2 PF13189.6 EST45075.1 - 0.022 14.9 0.1 0.056 13.6 0.0 1.8 2 1 0 2 2 2 0 Cytidylate kinase-like family AAA_29 PF13555.6 EST45075.1 - 0.032 14.0 0.1 0.07 12.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SKI PF01202.22 EST45075.1 - 0.035 14.2 0.5 0.076 13.1 0.0 1.9 2 1 0 2 2 2 0 Shikimate kinase ABC_tran PF00005.27 EST45075.1 - 0.054 14.0 1.6 0.092 13.3 1.6 1.6 1 1 0 1 1 1 0 ABC transporter dNK PF01712.19 EST45075.1 - 0.077 12.8 1.8 0.27 11.0 0.0 2.4 2 2 1 3 3 3 0 Deoxynucleoside kinase NACHT PF05729.12 EST45075.1 - 0.085 12.8 0.3 0.21 11.5 0.3 1.6 1 0 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 EST45075.1 - 0.092 12.6 0.1 0.26 11.2 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_14 PF13173.6 EST45075.1 - 0.12 12.4 1.1 0.27 11.3 0.3 2.2 1 1 1 2 2 2 0 AAA domain Complex1_LYR_2 PF13233.6 EST45075.1 - 0.12 13.1 2.5 0.32 11.8 2.5 1.9 1 1 0 1 1 1 0 Complex1_LYR-like AAA_25 PF13481.6 EST45075.1 - 0.24 10.9 0.1 0.57 9.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain RIFIN PF02009.16 EST45075.1 - 1.1 9.1 7.1 2.3 8.0 3.4 2.1 1 1 1 2 2 2 0 Rifin ANAPC4_WD40 PF12894.7 EST45076.1 - 0.043 14.1 0.1 0.085 13.2 0.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Topoisom_I PF01028.20 EST45076.1 - 0.044 13.0 1.5 0.071 12.4 1.5 1.3 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, catalytic core Tup_N PF08581.10 EST45076.1 - 0.5 10.7 9.5 0.06 13.7 4.0 2.2 2 1 0 2 2 2 0 Tup N-terminal DUF1471 PF07338.13 EST45077.1 - 0.0078 16.2 0.3 0.15 12.0 0.1 3.1 4 0 0 4 4 4 1 Protein of unknown function (DUF1471) BBP1_N PF15271.6 EST45077.1 - 5.1 7.9 8.6 0.34 11.7 2.4 2.2 2 1 0 2 2 2 0 Spindle pole body component BBP1, Mps2-binding protein DUF4922 PF16269.5 EST45079.1 - 0.056 13.2 0.1 0.074 12.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4922) Seryl_tRNA_N PF02403.22 EST45080.1 - 0.00089 19.5 17.4 0.0048 17.1 4.8 5.4 2 1 2 5 5 5 3 Seryl-tRNA synthetase N-terminal domain PapC_C PF13953.6 EST45080.1 - 0.0016 18.2 1.4 1.5 8.7 0.1 2.5 2 0 0 2 2 2 2 PapC C-terminal domain Diacid_rec PF05651.13 EST45080.1 - 0.0018 17.9 0.4 4.6 6.9 0.0 3.7 3 0 0 3 3 3 2 Putative sugar diacid recognition Spc7 PF08317.11 EST45080.1 - 0.0063 15.4 8.6 0.0063 15.4 8.6 5.1 2 1 3 5 5 5 3 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 EST45080.1 - 0.012 15.6 6.5 0.012 15.6 6.5 8.4 7 3 2 9 9 9 0 TATA element modulatory factor 1 DNA binding Sigma70_r4_2 PF08281.12 EST45080.1 - 0.022 14.4 2.7 0.75 9.5 0.4 2.9 2 0 0 2 2 2 0 Sigma-70, region 4 Peptidase_U32_C PF16325.5 EST45080.1 - 2.8 8.3 11.4 46 4.4 0.0 4.8 5 0 0 5 5 5 0 Peptidase family U32 C-terminal domain FUSC PF04632.12 EST45080.1 - 3.7 6.0 20.8 1.1 7.7 17.1 1.8 1 1 0 1 1 1 0 Fusaric acid resistance protein family AAA_18 PF13238.6 EST45081.1 - 2.4e-19 70.2 0.5 3.8e-19 69.5 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 EST45081.1 - 5.6e-06 26.8 0.2 1.7e-05 25.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 EST45081.1 - 7.5e-05 22.9 0.6 0.00023 21.3 0.6 1.7 1 1 0 1 1 1 1 Shikimate kinase AAA PF00004.29 EST45081.1 - 0.0014 19.1 0.0 0.0055 17.1 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EST45081.1 - 0.0025 17.5 0.1 0.0083 15.9 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EST45081.1 - 0.0046 17.1 0.0 0.2 11.8 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.6 EST45081.1 - 0.0084 16.4 0.0 0.012 15.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EST45081.1 - 0.016 15.2 4.8 0.21 11.6 0.4 2.1 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit dNK PF01712.19 EST45081.1 - 0.017 15.0 5.7 0.15 11.9 0.6 2.5 1 1 1 2 2 2 0 Deoxynucleoside kinase TM1586_NiRdase PF14512.6 EST45081.1 - 0.025 14.1 1.0 0.049 13.2 1.0 1.5 1 1 0 1 1 1 0 Putative TM nitroreductase AAA_22 PF13401.6 EST45081.1 - 0.075 13.3 0.9 0.13 12.5 0.9 1.8 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 EST45081.1 - 0.13 11.8 1.0 0.66 9.5 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 EST45081.1 - 0.24 11.3 2.6 0.26 11.2 0.2 2.0 2 1 0 2 2 2 0 RsgA GTPase AAA_14 PF13173.6 EST45081.1 - 0.89 9.6 4.7 3.7 7.6 4.7 2.0 1 1 0 1 1 1 0 AAA domain XRCC1_N PF01834.16 EST45082.1 - 0.094 12.7 0.2 0.3 11.1 0.1 1.9 2 0 0 2 2 2 0 XRCC1 N terminal domain DER1 PF04511.15 EST45085.1 - 5.3e-18 65.6 17.6 6.7e-18 65.3 17.6 1.0 1 0 0 1 1 1 1 Der1-like family MCM2_N PF12619.8 EST45086.1 - 0.0047 17.2 1.2 0.0047 17.2 1.2 2.7 2 1 0 2 2 2 1 Mini-chromosome maintenance protein 2 TRPM_tetra PF16519.5 EST45086.1 - 8.8 6.5 9.1 0.61 10.2 1.4 3.2 3 0 0 3 3 3 0 Tetramerisation domain of TRPM AAA PF00004.29 EST45090.1 - 4.1e-34 117.8 0.1 2.6e-20 73.2 0.0 3.3 2 1 1 3 3 3 2 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 EST45090.1 - 1e-10 41.3 0.0 0.0028 17.1 0.0 3.6 2 1 1 3 3 3 2 Bacterial TniB protein RuvB_N PF05496.12 EST45090.1 - 1.7e-09 37.7 0.0 0.0011 18.7 0.0 2.8 2 2 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EST45090.1 - 2.6e-09 37.5 1.2 0.025 14.8 0.1 4.6 2 2 1 3 3 3 2 AAA domain AAA_16 PF13191.6 EST45090.1 - 4.3e-09 37.0 3.8 0.0039 17.6 0.0 4.6 4 2 2 6 6 4 2 AAA ATPase domain AAA_19 PF13245.6 EST45090.1 - 7.7e-09 36.0 0.1 0.082 13.2 0.0 3.8 2 2 2 4 4 4 3 AAA domain ATPase_2 PF01637.18 EST45090.1 - 2.6e-08 34.1 0.1 0.0023 17.9 0.0 3.3 2 1 1 3 3 3 2 ATPase domain predominantly from Archaea AAA_5 PF07728.14 EST45090.1 - 6.2e-08 32.7 0.1 0.0079 16.2 0.0 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EST45090.1 - 5.6e-07 29.5 0.0 0.0019 17.9 0.0 2.8 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EST45090.1 - 7.6e-07 29.7 0.0 0.0028 18.2 0.0 2.7 2 1 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.6 EST45090.1 - 2.5e-06 27.7 0.2 0.0062 16.7 0.0 2.8 2 1 0 2 2 2 2 Sigma-54 interaction domain Bac_DnaA PF00308.18 EST45090.1 - 3.2e-06 27.1 0.1 9.1e-05 22.4 0.3 2.5 2 1 0 2 2 2 1 Bacterial dnaA protein IstB_IS21 PF01695.17 EST45090.1 - 3.7e-06 26.8 0.0 0.0027 17.5 0.0 3.1 3 1 0 3 3 2 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EST45090.1 - 5.3e-06 26.0 0.1 0.051 13.0 0.0 3.2 2 2 1 3 3 3 2 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 EST45090.1 - 1e-05 24.9 0.0 0.094 11.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) NACHT PF05729.12 EST45090.1 - 1.4e-05 25.1 2.5 0.097 12.6 0.1 4.2 2 2 1 3 3 3 1 NACHT domain AAA_11 PF13086.6 EST45090.1 - 2e-05 24.5 0.1 0.07 12.9 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_7 PF12775.7 EST45090.1 - 2.9e-05 23.7 0.0 0.23 10.9 0.0 3.7 3 0 0 3 3 3 1 P-loop containing dynein motor region NTPase_1 PF03266.15 EST45090.1 - 5.1e-05 23.3 0.1 0.025 14.5 0.0 3.4 2 2 1 3 3 3 1 NTPase RNA_helicase PF00910.22 EST45090.1 - 6.5e-05 23.3 0.0 0.081 13.3 0.0 3.3 2 1 0 2 2 2 1 RNA helicase AAA_28 PF13521.6 EST45090.1 - 7.2e-05 23.1 0.0 1.7 8.8 0.0 3.3 2 1 1 3 3 3 2 AAA domain AAA_33 PF13671.6 EST45090.1 - 0.00011 22.4 0.0 0.06 13.5 0.0 2.6 2 2 0 2 2 2 1 AAA domain SRP54 PF00448.22 EST45090.1 - 0.00028 20.6 0.0 0.45 10.1 0.0 3.2 2 1 0 2 2 2 1 SRP54-type protein, GTPase domain Rad17 PF03215.15 EST45090.1 - 0.00035 20.5 0.5 1.5 8.7 0.0 3.7 1 1 0 3 3 3 1 Rad17 P-loop domain Sigma54_activat PF00158.26 EST45090.1 - 0.00047 19.9 0.1 14 5.3 0.0 4.4 3 1 1 4 4 4 0 Sigma-54 interaction domain RsgA_GTPase PF03193.16 EST45090.1 - 0.00053 19.9 1.8 1.4 8.8 0.1 3.7 2 1 1 4 4 4 1 RsgA GTPase cobW PF02492.19 EST45090.1 - 0.00092 18.8 0.0 0.075 12.6 0.0 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 EST45090.1 - 0.0011 18.9 0.0 2 8.4 0.0 2.9 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 EST45090.1 - 0.0018 18.8 0.1 2.7 8.5 0.0 2.8 2 2 0 2 2 2 1 ABC transporter AAA_2 PF07724.14 EST45090.1 - 0.0018 18.4 0.0 3.5 7.7 0.0 3.5 2 2 0 2 2 2 1 AAA domain (Cdc48 subfamily) MMR_HSR1 PF01926.23 EST45090.1 - 0.0031 17.6 0.0 1.5 8.9 0.0 3.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 EST45090.1 - 0.0037 17.0 0.0 2.1 8.2 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 EST45090.1 - 0.0042 16.8 0.0 3.1 7.5 0.0 2.8 2 1 1 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 EST45090.1 - 0.0045 16.8 0.0 2.4 7.9 0.0 2.7 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.6 EST45090.1 - 0.0075 16.7 0.1 0.63 10.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 EST45090.1 - 0.0092 15.8 0.1 0.17 11.6 0.0 2.8 2 2 0 2 2 2 1 Conserved hypothetical ATP binding protein MCM PF00493.23 EST45090.1 - 0.016 14.3 0.1 0.67 9.0 0.0 2.8 3 0 0 3 3 3 0 MCM P-loop domain KAP_NTPase PF07693.14 EST45090.1 - 0.019 14.2 0.6 0.16 11.2 0.6 2.8 1 1 0 1 1 1 0 KAP family P-loop domain ATPase PF06745.13 EST45090.1 - 0.039 13.3 0.3 18 4.6 0.0 3.3 4 0 0 4 4 4 0 KaiC AAA_3 PF07726.11 EST45090.1 - 0.057 13.3 0.0 18 5.2 0.0 3.7 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Carbam_trans_C PF16861.5 EST45090.1 - 0.091 12.3 0.1 0.18 11.4 0.1 1.4 1 0 0 1 1 1 0 Carbamoyltransferase C-terminus ResIII PF04851.15 EST45090.1 - 0.47 10.4 3.8 17 5.4 0.0 4.0 2 1 1 4 4 4 0 Type III restriction enzyme, res subunit AAA_23 PF13476.6 EST45090.1 - 4.7 7.7 0.0 4.7 7.7 0.0 3.7 3 1 0 4 4 4 0 AAA domain BetaGal_dom4_5 PF13364.6 EST45092.1 - 0.058 14.0 0.1 0.19 12.3 0.1 1.9 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain ATP-gua_PtransN PF02807.15 EST45092.1 - 0.07 13.5 0.0 0.65 10.4 0.0 2.8 2 0 0 2 2 2 0 ATP:guanido phosphotransferase, N-terminal domain SNF2_N PF00176.23 EST45094.1 - 9.1e-58 195.6 6.5 2.1e-57 194.4 6.5 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 EST45094.1 - 5.2e-23 81.2 1.3 3e-22 78.8 1.3 2.5 1 0 0 1 1 1 1 SLIDE Helicase_C PF00271.31 EST45094.1 - 5.5e-19 68.6 3.3 2.2e-17 63.4 0.3 3.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 EST45094.1 - 4.6e-07 29.8 0.2 1.4e-06 28.2 0.2 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase SF3A3 PF16837.5 EST45094.1 - 1.9 9.1 7.3 0.69 10.5 0.5 3.0 2 0 0 2 2 2 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 Folliculin PF11704.8 EST45094.1 - 5.3 6.9 11.0 4.1 7.3 1.6 3.5 3 1 0 3 3 3 0 Vesicle coat protein involved in Golgi to plasma membrane transport Pkinase PF00069.25 EST45095.1 - 3.3e-57 193.9 3.3 4.2e-42 144.3 0.2 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EST45095.1 - 3.2e-27 95.4 0.2 5.9e-21 74.9 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EST45095.1 - 1.1e-10 41.3 0.3 0.014 14.7 0.1 3.4 2 1 1 3 3 3 3 Kinase-like POLO_box PF00659.18 EST45095.1 - 1.2e-10 41.4 3.7 3.7e-08 33.4 0.1 3.1 2 0 0 2 2 2 2 POLO box duplicated region Leader_Erm PF08253.11 EST45095.1 - 0.12 12.6 0.1 0.7 10.3 0.1 2.3 1 0 0 1 1 1 0 Erm Leader peptide YozE_SAM_like PF06855.12 EST45095.1 - 2.4 8.4 7.6 3.8 7.8 0.3 3.4 3 0 0 3 3 3 0 YozE SAM-like fold Il13Ra_Ig PF18001.1 EST45096.1 - 0.41 10.8 5.8 0.09 12.9 1.4 2.3 2 1 0 2 2 2 0 Interleukin-13 receptor subunit alpha Ig-like domain DUF948 PF06103.11 EST45096.1 - 1.8 8.9 9.7 1.8 8.9 1.3 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) HEAT PF02985.22 EST45097.1 - 3.9e-06 26.7 2.9 0.024 14.9 0.0 5.9 6 0 0 6 6 5 1 HEAT repeat DUF1981 PF09324.10 EST45097.1 - 3e-05 23.8 6.9 0.0099 15.7 0.2 4.1 4 0 0 4 4 4 2 Domain of unknown function (DUF1981) HEAT_2 PF13646.6 EST45097.1 - 0.00029 21.2 0.0 0.13 12.7 0.0 3.8 4 0 0 4 4 3 1 HEAT repeats DUF3730 PF12530.8 EST45097.1 - 0.00043 19.9 0.2 1.1 8.8 0.0 4.0 2 2 1 4 4 4 2 Protein of unknown function (DUF3730) UME PF08064.13 EST45097.1 - 0.0014 18.5 1.0 0.0014 18.5 1.0 5.6 4 1 2 6 6 5 1 UME (NUC010) domain DUF5071 PF16804.5 EST45097.1 - 0.0044 17.3 11.9 2.9 8.2 1.0 6.4 5 1 1 6 6 6 1 Domain of unknown function (DUF5071) HEAT_EZ PF13513.6 EST45097.1 - 0.01 16.3 0.0 14 6.3 0.0 4.2 3 1 1 4 4 4 0 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EST45097.1 - 0.03 14.9 5.1 1.9 9.1 0.1 4.9 3 2 1 4 4 4 0 Vacuolar 14 Fab1-binding region ER PF01133.17 EST45097.1 - 0.37 10.9 3.7 0.46 10.5 0.5 2.9 2 0 0 2 2 2 0 Enhancer of rudimentary GlutR_dimer PF00745.20 EST45097.1 - 1.6 9.2 4.2 5.3 7.6 0.1 3.8 4 0 0 4 4 4 0 Glutamyl-tRNAGlu reductase, dimerisation domain SoDot-IcmSS PF16848.5 EST45097.1 - 2.9 7.8 8.7 1.8 8.5 1.1 2.9 3 0 0 3 3 3 0 Substrate of the Dot/Icm secretion system, putative CRAL_TRIO PF00650.20 EST45097.1 - 4.6 6.9 6.2 6.8 6.4 0.2 3.6 3 1 0 4 4 4 0 CRAL/TRIO domain Pkinase PF00069.25 EST45098.1 - 4.6e-52 177.0 1.8 6.4e-52 176.5 1.8 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST45098.1 - 1.6e-35 122.6 0.2 2.2e-35 122.2 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EST45098.1 - 2e-05 23.6 0.1 3.4e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EST45098.1 - 0.0012 18.2 1.4 0.0012 18.2 1.4 2.1 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 EST45098.1 - 0.0035 17.3 0.0 0.024 14.6 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 EST45099.1 - 4.8e-53 180.2 1.5 6.4e-53 179.8 1.5 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST45099.1 - 2e-33 115.8 0.2 3.2e-33 115.1 0.2 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EST45099.1 - 8.7e-14 51.5 0.3 1.4e-13 50.8 0.3 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EST45099.1 - 3.1e-08 33.0 2.5 3.1e-08 33.0 2.5 2.0 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EST45099.1 - 1.2e-06 27.6 0.3 2.4e-06 26.6 0.3 1.5 1 1 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EST45099.1 - 0.00048 19.8 1.7 0.67 9.5 0.1 2.6 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EST45099.1 - 0.0027 17.7 0.0 0.0041 17.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EST45099.1 - 0.021 14.2 1.9 0.056 12.8 0.3 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family La_HTH_kDCL PF18177.1 EST45099.1 - 0.12 12.6 0.1 0.39 11.0 0.1 1.9 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain TFIID_30kDa PF03540.13 EST45100.1 - 0.00035 20.5 0.0 0.0016 18.4 0.0 1.9 2 0 0 2 2 2 1 Transcription initiation factor TFIID 23-30kDa subunit SlyX PF04102.12 EST45101.1 - 0.00033 21.2 7.4 0.00033 21.2 7.4 2.8 2 1 1 3 3 3 1 SlyX RGS-like PF09128.11 EST45101.1 - 0.00061 19.6 1.8 0.00089 19.0 1.8 1.3 1 0 0 1 1 1 1 Regulator of G protein signalling-like domain GP41 PF00517.17 EST45101.1 - 0.029 14.3 5.7 0.043 13.7 5.1 1.7 1 1 0 1 1 1 0 Retroviral envelope protein MMPL PF03176.15 EST45101.1 - 0.12 11.2 0.8 0.16 10.9 0.8 1.1 1 0 0 1 1 1 0 MMPL family DUF641 PF04859.12 EST45101.1 - 0.18 12.1 5.1 0.18 12.1 2.4 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) CENP-F_leu_zip PF10473.9 EST45101.1 - 0.44 10.6 7.9 0.6 10.1 7.1 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.12 EST45101.1 - 0.45 10.6 11.5 2.7 8.0 11.5 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 EST45101.1 - 0.57 10.2 9.8 0.25 11.4 4.2 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) CLZ PF16526.5 EST45101.1 - 1 9.8 8.1 3.1 8.2 1.2 3.5 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Csm1_N PF18504.1 EST45101.1 - 9.2 6.7 15.8 0.23 11.8 0.8 3.7 2 1 2 4 4 4 0 Csm1 N-terminal domain Colicin_immun PF09204.10 EST45102.1 - 0.022 15.3 0.8 0.31 11.6 0.0 3.0 2 0 0 2 2 2 0 Bacterial self-protective colicin-like immunity Peptidase_C1 PF00112.23 EST45105.1 - 1.4e-19 71.1 0.1 4.1e-19 69.5 0.1 1.8 1 1 0 1 1 1 1 Papain family cysteine protease TMEM154 PF15102.6 EST45105.1 - 0.047 13.6 0.0 0.074 13.0 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family GRP PF07172.11 EST45105.1 - 0.12 13.1 0.4 7.7 7.3 0.1 2.7 3 0 0 3 3 3 0 Glycine rich protein family tRNA_edit PF04073.15 EST45108.1 - 0.0013 18.8 6.0 3.1 7.9 0.1 3.4 2 1 1 3 3 3 3 Aminoacyl-tRNA editing domain Anoct_dimer PF16178.5 EST45108.1 - 0.78 9.4 2.2 27 4.4 0.3 3.1 2 1 0 2 2 2 0 Dimerisation domain of Ca+-activated chloride-channel, anoctamin RIBIOP_C PF04950.12 EST45109.1 - 2.1e-57 194.8 0.1 2.1e-57 194.8 0.1 2.9 2 1 1 3 3 3 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EST45109.1 - 6.7e-10 38.9 0.5 2.6e-09 37.0 0.0 2.4 2 0 0 2 2 2 1 AARP2CN (NUC121) domain AAA_14 PF13173.6 EST45109.1 - 0.0008 19.4 1.2 0.012 15.7 0.0 3.3 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 EST45109.1 - 0.005 16.9 2.1 0.013 15.6 0.3 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EST45109.1 - 0.0094 15.5 7.3 0.036 13.6 0.5 3.0 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EST45109.1 - 0.01 16.2 0.8 0.041 14.3 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain AAA PF00004.29 EST45109.1 - 0.03 14.7 0.1 0.1 13.0 0.1 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EST45109.1 - 0.034 14.1 0.2 1.2 9.1 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 EST45109.1 - 0.077 13.1 0.2 0.61 10.2 0.2 2.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EST45109.1 - 0.15 12.3 0.6 0.53 10.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EST45109.1 - 0.26 11.8 0.0 0.26 11.8 0.0 4.1 3 1 0 3 3 2 0 ABC transporter Sp38 PF07354.12 EST45110.1 - 0.0028 17.1 0.1 0.0037 16.7 0.1 1.2 1 0 0 1 1 1 1 Zona-pellucida-binding protein (Sp38) RGP PF03214.13 EST45110.1 - 0.04 13.1 0.0 0.058 12.6 0.0 1.3 1 0 0 1 1 1 0 Reversibly glycosylated polypeptide DUF896 PF05979.12 EST45110.1 - 0.045 13.6 2.0 0.064 13.1 0.7 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) DDE_Tnp_IS240 PF13610.6 EST45110.1 - 0.063 13.5 1.2 0.094 12.9 0.8 1.7 1 1 0 1 1 1 0 DDE domain CH_2 PF06294.11 EST45110.1 - 0.064 13.4 0.9 11 6.2 0.1 2.5 1 1 1 2 2 2 0 CH-like domain in sperm protein KIAA1430 PF13879.6 EST45111.1 - 0.037 14.8 7.4 0.048 14.4 7.4 1.2 1 0 0 1 1 1 0 KIAA1430 homologue Prp18 PF02840.15 EST45111.1 - 0.05 13.6 6.4 0.067 13.2 6.4 1.1 1 0 0 1 1 1 0 Prp18 domain DUF2203 PF09969.9 EST45111.1 - 0.12 13.1 1.7 0.15 12.7 1.7 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) PIH1 PF08190.12 EST45112.1 - 0.03 13.8 0.4 0.053 13.0 0.4 1.4 1 0 0 1 1 1 0 PIH1 N-terminal domain Peptidase_S28 PF05577.12 EST45113.1 - 7e-58 196.4 11.0 2.9e-57 194.4 11.0 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 EST45113.1 - 0.0012 18.3 0.1 0.0026 17.3 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family TM1586_NiRdase PF14512.6 EST45114.1 - 6.5e-34 117.4 0.0 7.5e-34 117.2 0.0 1.0 1 0 0 1 1 1 1 Putative TM nitroreductase Nitroreductase PF00881.24 EST45114.1 - 4.3e-08 33.4 0.4 0.022 14.8 0.0 3.4 2 2 2 4 4 4 2 Nitroreductase family Amastin PF07344.11 EST45115.1 - 0.00065 19.6 1.6 0.00078 19.3 1.6 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF2721 PF11026.8 EST45115.1 - 0.0022 17.9 1.6 0.0027 17.6 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2721) SecD_SecF PF02355.16 EST45115.1 - 0.0073 15.7 1.1 0.0083 15.5 1.1 1.1 1 0 0 1 1 1 1 Protein export membrane protein DUF2207 PF09972.9 EST45115.1 - 0.013 14.3 0.6 0.015 14.1 0.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SUR7 PF06687.12 EST45115.1 - 0.015 14.9 3.0 0.018 14.7 3.0 1.1 1 0 0 1 1 1 0 SUR7/PalI family DUF2975 PF11188.8 EST45115.1 - 0.04 13.8 4.9 0.055 13.3 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) DUF1494 PF07379.11 EST45115.1 - 0.049 13.5 2.7 0.52 10.1 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1494) E1-E2_ATPase PF00122.20 EST45115.1 - 1 8.9 6.4 9.6 5.7 5.6 2.0 1 1 1 2 2 2 0 E1-E2 ATPase Orf78 PF06024.12 EST45115.1 - 3.4 8.0 9.4 0.059 13.7 1.0 1.9 1 1 1 2 2 2 0 Orf78 (ac78) Chromo PF00385.24 EST45117.1 - 0.014 15.3 0.2 0.035 14.0 0.2 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF3876 PF12992.7 EST45117.1 - 2.7 8.1 4.8 16 5.6 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function, B. Theta Gene description (DUF3876) PAP2 PF01569.21 EST45118.1 - 4.8e-11 42.6 8.1 1.5e-10 41.0 5.2 2.1 1 1 1 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 EST45118.1 - 0.0079 15.9 0.5 0.011 15.4 0.1 1.5 2 0 0 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 EST45118.1 - 0.1 12.7 0.2 0.38 10.9 0.0 2.0 2 0 0 2 2 2 0 Divergent PAP2 family Zn-ribbon_8 PF09723.10 EST45119.1 - 0.014 15.5 1.4 0.03 14.4 1.4 1.6 1 0 0 1 1 1 0 Zinc ribbon domain MCM_OB PF17207.3 EST45119.1 - 0.029 14.2 3.1 0.037 13.9 3.1 1.2 1 0 0 1 1 1 0 MCM OB domain RhoGEF PF00621.20 EST45119.1 - 0.055 13.7 0.0 0.07 13.4 0.0 1.1 1 0 0 1 1 1 0 RhoGEF domain DUF5481 PF17578.2 EST45119.1 - 0.11 12.9 0.1 0.2 12.1 0.1 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5481) DUF4407 PF14362.6 EST45120.1 - 4 6.7 8.1 5.1 6.4 8.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MOZ_SAS PF01853.18 EST45122.1 - 1.3e-61 207.4 0.2 2.2e-61 206.6 0.2 1.4 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EST45122.1 - 3.9e-20 71.2 3.5 8.6e-20 70.1 3.5 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 EST45122.1 - 0.00065 20.1 0.0 0.0025 18.2 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Tudor-knot PF11717.8 EST45122.1 - 0.0032 17.3 0.0 0.0032 17.3 0.0 2.0 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.25 EST45122.1 - 0.011 15.9 0.0 0.026 14.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family RIIa PF02197.17 EST45123.1 - 7.9e-05 22.2 0.1 0.00022 20.8 0.0 1.7 2 0 0 2 2 2 1 Regulatory subunit of type II PKA R-subunit Kinesin PF00225.23 EST45124.1 - 9.9e-97 323.8 5.9 2.3e-96 322.6 5.9 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EST45124.1 - 7.6e-20 71.4 2.8 4.4e-19 68.9 2.8 2.5 1 0 0 1 1 1 1 Microtubule binding RBD-FIP PF09457.10 EST45124.1 - 0.21 11.5 5.5 0.3 11.1 1.1 3.1 2 0 0 2 2 2 0 FIP domain Cyclin_N PF00134.23 EST45127.1 - 9e-13 48.1 0.6 1.3e-12 47.5 0.6 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EST45127.1 - 1e-09 38.9 1.4 1.4e-09 38.5 1.4 1.3 1 0 0 1 1 1 1 Cyclin DUF3755 PF12579.8 EST45128.1 - 0.027 14.1 2.3 0.29 10.8 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3755) TFIIS_C PF01096.18 EST45130.1 - 3e-13 49.4 5.6 3e-13 49.4 5.6 1.7 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Baculo_LEF5_C PF11792.8 EST45130.1 - 0.00029 20.5 1.3 0.00076 19.1 1.3 1.7 1 0 0 1 1 1 1 Baculoviridae late expression factor 5 C-terminal domain TFIIS_M PF07500.14 EST45130.1 - 0.0016 18.9 0.3 0.0032 17.9 0.3 1.5 1 1 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TF_Zn_Ribbon PF08271.12 EST45130.1 - 0.035 13.6 0.3 0.07 12.7 0.3 1.5 1 1 0 1 1 1 0 TFIIB zinc-binding zf-H2C2_2 PF13465.6 EST45130.1 - 0.062 13.8 2.1 11 6.7 0.4 2.3 2 0 0 2 2 2 0 Zinc-finger double domain HypA PF01155.19 EST45130.1 - 0.093 12.8 0.4 0.17 11.9 0.4 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA C1_4 PF07975.12 EST45130.1 - 1.2 9.4 3.6 2.4 8.5 3.6 1.5 1 0 0 1 1 1 0 TFIIH C1-like domain FRP PF18032.1 EST45131.1 - 0.055 14.1 0.1 0.076 13.6 0.1 1.2 1 0 0 1 1 1 0 Photoprotection regulator fluorescence recovery protein Amdase PF17645.1 EST45131.1 - 0.086 12.4 0.1 0.11 12.1 0.1 1.1 1 0 0 1 1 1 0 Arylmalonate decarboxylase Inhibitor_G39P PF11417.8 EST45132.1 - 0.035 14.6 0.2 0.067 13.7 0.2 1.4 1 0 0 1 1 1 0 Loader and inhibitor of phage G40P PAPS_reduct PF01507.19 EST45132.1 - 0.039 14.0 1.2 0.052 13.6 1.2 1.2 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family DUF525 PF04379.14 EST45132.1 - 0.13 12.6 0.9 0.33 11.2 0.5 1.8 1 1 0 1 1 1 0 ApaG domain DUF4041 PF13250.6 EST45132.1 - 0.14 12.1 1.6 7.6 6.5 0.7 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4041) Phage_GPO PF05929.11 EST45132.1 - 0.19 11.3 5.6 0.17 11.4 3.9 1.6 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase FlhD PF05247.13 EST45134.1 - 0.0014 18.9 0.6 0.009 16.3 0.6 2.5 1 0 0 1 1 1 1 Flagellar transcriptional activator (FlhD) Cyclin_C PF02984.19 EST45135.1 - 0.17 12.0 1.1 0.7 10.0 0.4 2.3 2 0 0 2 2 2 0 Cyclin, C-terminal domain eIF-1a PF01176.19 EST45136.1 - 2.5e-08 33.6 0.0 3.6e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Terminase_4 PF05119.12 EST45136.1 - 0.059 13.8 0.8 0.45 11.0 0.4 2.1 2 0 0 2 2 2 0 Phage terminase, small subunit Nitroreductase PF00881.24 EST45137.1 - 4.6e-19 69.1 0.9 3.1e-18 66.4 0.9 1.9 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 EST45137.1 - 3.1e-10 40.0 1.6 0.0056 16.3 0.1 3.1 1 1 2 3 3 3 3 Putative TM nitroreductase Fer4 PF00037.27 EST45137.1 - 2.1e-08 33.6 12.7 0.00011 21.8 4.0 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 EST45137.1 - 1e-06 28.7 21.5 6.4e-05 23.0 12.2 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 EST45137.1 - 1.2e-06 28.3 13.7 0.0037 17.3 4.4 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 EST45137.1 - 1.4e-06 28.3 13.3 2.5e-06 27.6 13.3 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 EST45137.1 - 2.5e-06 27.2 12.1 0.002 18.1 2.2 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 EST45137.1 - 1.4e-05 25.1 11.8 2.9e-05 24.1 11.8 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 EST45137.1 - 1.7e-05 25.3 14.4 0.00014 22.4 15.1 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 EST45137.1 - 5.1e-05 23.6 6.2 0.051 14.0 0.2 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_22 PF17179.4 EST45137.1 - 0.002 18.9 6.3 0.16 12.8 0.3 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 EST45137.1 - 0.0022 18.9 10.7 0.049 14.6 1.0 2.4 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_4 PF12800.7 EST45137.1 - 0.011 16.2 17.6 0.22 12.1 4.4 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Atg8 PF02991.16 EST45137.1 - 0.068 13.4 0.1 0.12 12.6 0.1 1.4 1 1 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like Fer4_15 PF13459.6 EST45137.1 - 0.086 13.6 5.9 2.8 8.7 0.6 2.4 2 0 0 2 2 2 0 4Fe-4S single cluster domain KicB PF03882.14 EST45137.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 MukF winged-helix domain Fer4_17 PF13534.6 EST45137.1 - 0.21 12.2 15.8 2.3 8.8 4.8 2.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 EST45137.1 - 0.28 12.2 21.2 1 10.5 3.9 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 EST45137.1 - 5.8 7.2 11.6 87 3.4 11.5 2.2 1 1 0 1 1 1 0 4Fe-4S dicluster domain TGT PF01702.18 EST45138.1 - 8.4e-14 51.5 3.4 9.8e-14 51.3 3.4 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase NGF PF00243.18 EST45138.1 - 0.011 16.0 1.6 0.017 15.3 1.1 1.6 2 0 0 2 2 2 0 Nerve growth factor family DUF4422 PF14393.6 EST45139.1 - 0.16 11.8 4.0 12 5.7 0.4 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4422) TIM PF00121.18 EST45141.1 - 2.7e-83 279.1 1.9 3.1e-83 278.9 1.9 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase E2F_CC-MB PF16421.5 EST45142.1 - 6.1 7.3 11.1 0.4 11.1 2.3 2.5 2 1 0 2 2 2 0 E2F transcription factor CC-MB domain Flavodoxin_1 PF00258.25 EST45144.1 - 1.7e-16 60.7 0.0 2.1e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 EST45144.1 - 0.00047 20.4 0.0 0.00063 20.0 0.0 1.3 1 1 0 1 1 1 1 Flavodoxin domain Flavodoxin_NdrI PF07972.11 EST45144.1 - 0.0089 16.2 0.2 0.01 16.0 0.2 1.2 1 0 0 1 1 1 1 NrdI Flavodoxin like Flavodoxin_3 PF12641.7 EST45144.1 - 0.015 15.0 0.3 0.052 13.2 0.3 1.8 1 1 0 1 1 1 0 Flavodoxin domain UNC45-central PF11701.8 EST45145.1 - 0.016 15.1 0.5 0.03 14.3 0.4 1.4 1 1 0 1 1 1 0 Myosin-binding striated muscle assembly central PilX_N PF14341.6 EST45147.1 - 0.091 12.7 0.5 0.11 12.5 0.5 1.2 1 0 0 1 1 1 0 PilX N-terminal AKAP7_RIRII_bdg PF10470.9 EST45149.1 - 0.016 15.2 1.3 6.5 6.9 0.1 2.4 2 0 0 2 2 2 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein Phage_TAC_6 PF09550.10 EST45149.1 - 0.062 13.7 0.1 0.11 13.0 0.1 1.4 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC Tubulin PF00091.25 EST45150.1 - 7.1e-66 222.2 0.0 1.1e-65 221.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EST45150.1 - 5.8e-51 171.9 0.1 1.1e-50 171.0 0.1 1.5 2 0 0 2 2 2 1 Tubulin C-terminal domain DUF4154 PF13689.6 EST45152.1 - 0.01 16.0 0.7 0.053 13.8 0.7 2.2 1 0 0 1 1 1 0 YfiR/HmsC-like Vac14_Fab1_bd PF12755.7 EST45152.1 - 0.73 10.5 7.6 5.3 7.7 0.8 4.4 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region FKBP_N_2 PF18023.1 EST45152.1 - 7.5 6.7 9.6 11 6.1 0.8 4.1 3 0 0 3 3 3 0 BDBT FKBP like N-terminal Ank_2 PF12796.7 EST45153.1 - 2.4e-14 53.7 0.0 2.9e-09 37.4 0.0 3.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EST45153.1 - 1.3e-09 38.1 0.0 0.00012 22.3 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EST45153.1 - 2.5e-09 37.5 0.1 8.7e-06 26.2 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EST45153.1 - 9.7e-08 32.1 0.0 0.052 13.9 0.0 4.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EST45153.1 - 1.3e-05 25.2 0.4 0.16 12.6 0.0 5.0 5 0 0 5 5 5 1 Ankyrin repeat UCH PF00443.29 EST45153.1 - 3.1 7.2 9.3 7.1 6.0 7.9 2.2 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DUF5048 PF16467.5 EST45154.1 - 0.45 10.8 3.4 0.93 9.8 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5048) MDFI PF15316.6 EST45154.1 - 1.6 8.8 6.9 2.9 7.9 6.9 1.4 1 0 0 1 1 1 0 MyoD family inhibitor Cbl_N3 PF02762.14 EST45157.1 - 0.059 13.2 1.0 0.19 11.6 1.0 2.0 1 1 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain BPS1 PF05633.11 EST45157.1 - 0.15 11.0 0.8 0.22 10.5 0.8 1.1 1 0 0 1 1 1 0 Protein BYPASS1-related TBCA PF02970.16 EST45158.1 - 0.086 13.2 4.5 0.34 11.3 3.5 2.5 1 1 0 1 1 1 0 Tubulin binding cofactor A HD_3 PF13023.6 EST45158.1 - 0.12 12.3 2.0 0.22 11.4 1.4 1.7 1 1 0 1 1 1 0 HD domain DUF2935 PF11155.8 EST45158.1 - 0.54 10.6 5.2 1.2 9.4 0.6 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) APG6_N PF17675.1 EST45158.1 - 3.1 8.3 11.7 0.32 11.5 4.9 2.6 2 2 0 2 2 2 0 Apg6 coiled-coil region CDC45 PF02724.14 EST45159.1 - 5.7e-05 21.6 23.5 0.0019 16.6 23.5 2.4 1 1 0 1 1 1 1 CDC45-like protein DUF763 PF05559.11 EST45159.1 - 0.0033 16.7 2.2 0.0068 15.6 2.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF763) HEAT PF02985.22 EST45161.1 - 7.5e-06 25.8 0.1 2.9 8.4 0.0 6.3 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 EST45161.1 - 0.025 15.1 1.3 7.9 7.1 0.0 4.1 6 0 0 6 6 6 0 HEAT-like repeat TAF6_C PF07571.13 EST45161.1 - 0.14 12.5 1.2 12 6.3 0.0 4.4 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain Exo_endo_phos PF03372.23 EST45162.1 - 1.2e-10 41.3 0.0 1.5e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 EST45162.1 - 6.1e-05 22.8 0.0 0.00026 20.8 0.0 2.0 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Proteasome PF00227.26 EST45163.1 - 3.9e-39 134.1 1.4 4.6e-39 133.9 1.4 1.1 1 0 0 1 1 1 1 Proteasome subunit Transglut_core PF01841.19 EST45164.1 - 3.6e-08 33.8 0.0 0.0048 17.3 0.0 2.5 2 0 0 2 2 2 2 Transglutaminase-like superfamily Polo_box_2 PF18531.1 EST45164.1 - 0.28 11.3 3.0 0.34 11.0 0.8 2.3 2 0 0 2 2 2 0 Polo box domain Ribosomal_S28e PF01200.18 EST45165.1 - 1.9e-26 91.8 2.0 2.1e-26 91.7 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e WD40 PF00400.32 EST45166.1 - 9.5e-08 32.6 0.0 0.0074 17.1 0.0 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EST45166.1 - 0.0024 18.1 0.1 0.033 14.5 0.0 3.0 2 2 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EST45167.1 - 1.1e-13 51.4 3.0 0.091 13.7 0.0 7.4 7 1 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EST45167.1 - 3.7e-08 33.6 0.0 0.00035 20.8 0.0 2.9 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EST45167.1 - 7.2e-05 22.0 3.3 0.0013 17.9 0.3 2.1 1 1 0 2 2 2 2 Coatomer WD associated region Nup160 PF11715.8 EST45167.1 - 0.00031 19.5 0.5 0.19 10.3 0.0 2.8 2 1 1 3 3 3 2 Nucleoporin Nup120/160 WD40_like PF17005.5 EST45167.1 - 0.0012 18.2 1.2 0.0042 16.5 0.3 2.2 2 1 0 3 3 3 1 WD40-like domain BBS2_Mid PF14783.6 EST45167.1 - 0.0051 16.8 1.4 0.063 13.3 0.0 3.0 2 2 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Ge1_WD40 PF16529.5 EST45167.1 - 0.0093 15.0 1.8 0.69 8.8 0.1 3.0 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 EST45167.1 - 0.057 12.0 0.0 0.33 9.4 0.0 2.0 1 1 1 2 2 2 0 Cytochrome D1 heme domain TetR_C_13 PF16925.5 EST45168.1 - 0.00072 19.5 1.1 0.005 16.8 0.8 2.8 1 1 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain SapB_1 PF05184.15 EST45168.1 - 0.77 9.8 3.7 2.1 8.4 0.4 3.2 2 0 0 2 2 2 0 Saposin-like type B, region 1 YwpF PF14183.6 EST45170.1 - 0.074 13.1 1.6 1.3 9.0 0.1 2.5 2 1 0 2 2 2 0 YwpF-like protein zf-C3HC4_3 PF13920.6 EST45171.1 - 3.2e-09 36.5 55.4 6.1e-05 22.8 11.3 3.9 4 0 0 4 4 4 3 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EST45171.1 - 2.8e-05 24.2 63.0 0.066 13.4 15.1 3.8 3 0 0 3 3 3 3 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EST45171.1 - 6.1e-05 23.0 12.8 6.1e-05 23.0 12.8 4.0 3 0 0 3 3 3 2 RING-type zinc-finger zf-RING_5 PF14634.6 EST45171.1 - 0.0018 18.2 11.8 0.0018 18.2 11.8 4.3 3 1 1 4 4 4 2 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EST45171.1 - 0.0018 18.0 14.7 0.0018 18.0 14.7 3.6 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EST45171.1 - 0.0045 16.8 14.6 0.0045 16.8 14.6 3.7 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) CAP_GLY PF01302.25 EST45172.1 - 2.3e-13 50.0 0.0 4.3e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 EST45172.1 - 0.011 16.1 0.7 0.011 16.1 0.7 5.5 6 1 0 6 6 6 0 Leucine Rich repeats (2 copies) ATP-synt_C PF00137.21 EST45173.1 - 1.2e-19 70.4 27.7 1.3e-10 41.4 7.8 2.4 2 1 0 2 2 2 2 ATP synthase subunit C DUF1411 PF07199.11 EST45175.1 - 0.0015 18.2 0.9 0.0024 17.6 0.8 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1411) DUF3877 PF12993.7 EST45175.1 - 0.42 10.4 4.7 0.26 11.1 1.8 1.8 1 1 1 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3877) Pox_A_type_inc PF04508.12 EST45175.1 - 0.56 10.2 7.7 0.43 10.5 0.4 3.7 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat KLRAQ PF10205.9 EST45175.1 - 2.6 8.3 24.4 1.4 9.2 4.3 3.3 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein Cnn_1N PF07989.11 EST45175.1 - 2.6 8.3 22.0 0.064 13.4 4.5 3.6 2 1 2 4 4 4 0 Centrosomin N-terminal motif 1 YabA PF06156.13 EST45175.1 - 6.8 7.4 22.9 5.5 7.7 9.2 3.4 1 1 2 3 3 3 0 Initiation control protein YabA Sec20 PF03908.13 EST45177.1 - 0.68 9.9 8.8 3.9 7.5 2.7 2.7 2 0 0 2 2 2 0 Sec20 Glutaredoxin2_C PF04399.13 EST45177.1 - 4.9 7.0 6.9 0.75 9.6 1.5 2.3 2 1 1 3 3 3 0 Glutaredoxin 2, C terminal domain B9-C2 PF07162.11 EST45179.1 - 1.1e-22 81.1 0.0 1.2e-22 80.9 0.0 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein zf-rbx1 PF12678.7 EST45180.1 - 2.9e-08 33.9 0.2 2.9e-08 33.9 0.2 2.7 3 0 0 3 3 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EST45180.1 - 2.9e-06 27.0 3.9 3.5e-05 23.5 0.8 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EST45180.1 - 3.3e-06 27.0 0.2 3.3e-06 27.0 0.2 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 EST45180.1 - 3.6e-06 26.7 1.8 6.2e-05 22.8 0.4 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EST45180.1 - 8.1e-06 26.1 0.4 8.1e-06 26.1 0.4 3.0 3 0 0 3 3 2 1 Ring finger domain Zn_ribbon_17 PF17120.5 EST45180.1 - 7e-05 22.4 0.3 0.00026 20.5 0.3 1.9 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 EST45180.1 - 0.00012 21.7 3.9 0.011 15.5 0.7 3.1 2 0 0 2 2 2 2 RING-like zinc finger zf-RING_5 PF14634.6 EST45180.1 - 0.0013 18.7 0.2 0.0013 18.7 0.2 3.1 3 0 0 3 3 3 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EST45180.1 - 0.015 15.1 3.6 0.029 14.2 0.3 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EST45180.1 - 0.031 14.3 2.0 0.14 12.2 0.5 2.5 2 0 0 2 2 2 0 RING-type zinc-finger FANCL_C PF11793.8 EST45180.1 - 0.068 13.4 0.7 0.23 11.7 0.1 2.3 2 0 0 2 2 2 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 EST45180.1 - 0.12 12.3 0.1 0.12 12.3 0.1 3.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 EST45180.1 - 0.46 10.7 2.4 0.59 10.3 0.4 2.2 2 0 0 2 2 2 0 RING-variant domain ATG16 PF08614.11 EST45181.1 - 0.0096 16.2 15.9 0.0096 16.2 15.9 4.6 3 1 1 4 4 4 2 Autophagy protein 16 (ATG16) WD40 PF00400.32 EST45181.1 - 0.21 12.5 0.7 17 6.5 0.0 4.2 4 0 0 4 4 4 0 WD domain, G-beta repeat GTP_EFTU PF00009.27 EST45182.1 - 3.5e-31 108.3 2.3 2.6e-30 105.4 0.0 3.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EST45182.1 - 1.5e-15 57.2 0.8 4.2e-15 55.8 0.8 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 EST45182.1 - 4.6e-12 46.1 1.1 1.2e-05 25.6 0.0 3.5 2 1 1 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EST45182.1 - 5.9e-09 36.0 0.7 2.6e-08 34.0 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 EST45182.1 - 1.2e-07 31.5 1.0 2.3e-07 30.6 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Roc PF08477.13 EST45182.1 - 2.7e-06 27.6 0.0 1.1e-05 25.7 0.0 2.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 EST45182.1 - 2.4e-05 24.2 1.8 8.8e-05 22.4 0.0 2.6 2 1 0 2 2 2 1 Conserved hypothetical ATP binding protein Ras PF00071.22 EST45182.1 - 0.0012 18.4 0.4 0.0036 16.9 0.0 2.1 2 0 0 2 2 2 1 Ras family FeoB_N PF02421.18 EST45182.1 - 0.044 13.3 0.0 1 8.9 0.0 2.8 2 1 0 2 2 2 0 Ferrous iron transport protein B Dynamin_N PF00350.23 EST45182.1 - 0.49 10.4 0.0 0.49 10.4 0.0 4.6 3 1 0 3 3 2 0 Dynamin family RsgA_GTPase PF03193.16 EST45182.1 - 3 7.7 13.0 1.7 8.5 0.5 5.0 3 1 1 4 4 4 0 RsgA GTPase WxL PF13731.6 EST45182.1 - 8.3 6.4 11.6 2.8 7.9 8.3 1.8 1 1 0 1 1 1 0 WxL domain surface cell wall-binding NusA_N PF08529.11 EST45183.1 - 0.24 11.8 3.2 0.37 11.2 0.2 2.6 3 0 0 3 3 3 0 NusA N-terminal domain UQ_con PF00179.26 EST45184.1 - 4.2e-10 39.4 0.2 6.4e-10 38.8 0.2 1.3 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EST45184.1 - 0.043 14.1 0.5 0.064 13.5 0.2 1.5 1 1 1 2 2 2 0 RWD domain Kelch_5 PF13854.6 EST45186.1 - 6.7e-09 35.5 0.6 0.0005 20.0 0.0 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 EST45186.1 - 6.8e-08 32.5 0.3 0.033 14.5 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 EST45186.1 - 6.5e-07 29.5 0.2 0.04 14.2 0.0 4.1 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_4 PF13418.6 EST45186.1 - 6.9e-07 29.2 0.8 0.075 13.1 0.0 3.9 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 EST45186.1 - 0.0001 22.1 0.3 1.5 9.0 0.0 4.1 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.25 EST45186.1 - 0.00084 18.9 0.1 2.5 7.7 0.0 4.0 4 0 0 4 4 4 1 Kelch motif UPF0697 PF15117.6 EST45186.1 - 0.035 14.2 0.0 0.067 13.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0697 RNA_pol_Rpb1_5 PF04998.17 EST45187.1 - 4.2e-49 167.4 0.0 4.2e-49 167.4 0.0 2.6 2 2 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EST45187.1 - 4.4e-49 166.9 0.4 2.6e-29 102.6 0.1 3.1 2 0 0 2 2 2 2 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 EST45187.1 - 7.3e-31 107.7 13.5 1.3e-15 57.5 0.0 4.8 3 1 1 4 4 4 3 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 EST45187.1 - 2.9e-20 72.8 2.8 2.9e-20 72.8 2.8 4.0 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EST45187.1 - 7.6e-15 54.8 1.3 5.6e-14 52.0 1.3 2.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 LRR_6 PF13516.6 EST45188.1 - 4.3e-09 35.7 22.0 0.024 14.7 0.0 9.0 9 0 0 9 9 9 4 Leucine Rich repeat LRR_8 PF13855.6 EST45188.1 - 0.0058 16.4 28.2 0.4 10.5 0.5 7.8 7 1 2 9 9 9 5 Leucine rich repeat LRR_4 PF12799.7 EST45188.1 - 0.011 16.2 32.3 0.27 11.7 0.8 7.7 6 1 2 8 8 8 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EST45188.1 - 1.6 9.6 23.1 25 6.0 0.1 9.8 11 1 0 11 11 11 0 Leucine Rich Repeat WD40 PF00400.32 EST45189.1 - 0.00066 20.4 0.9 2.8 9.0 0.2 3.3 2 1 1 3 3 3 2 WD domain, G-beta repeat WD40_like PF17005.5 EST45189.1 - 0.14 11.5 11.3 0.16 11.2 8.7 2.2 1 1 1 2 2 2 0 WD40-like domain POLO_box PF00659.18 EST45190.1 - 0.095 12.9 0.2 0.26 11.5 0.2 1.9 1 1 0 1 1 1 0 POLO box duplicated region PP2C PF00481.21 EST45191.1 - 2.3e-31 109.4 0.1 4e-31 108.6 0.1 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EST45191.1 - 0.0029 17.3 0.0 2.6 7.6 0.0 2.6 2 1 0 2 2 2 2 Protein phosphatase 2C CheB_methylest PF01339.17 EST45192.1 - 6.6 6.4 8.1 0.59 9.8 0.3 2.6 3 0 0 3 3 3 0 CheB methylesterase LRR_4 PF12799.7 EST45193.1 - 1.5e-15 57.1 90.8 6.7e-05 23.2 1.7 10.1 8 2 3 11 11 11 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EST45193.1 - 0.11 12.3 71.7 0.24 11.2 1.9 9.1 5 3 2 8 8 8 0 Leucine rich repeat DUF525 PF04379.14 EST45194.1 - 0.13 12.5 0.5 0.31 11.3 0.1 1.8 2 0 0 2 2 2 0 ApaG domain Spore_II_R PF09551.10 EST45194.1 - 0.82 10.1 3.8 1.7 9.1 3.7 1.6 1 1 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) PAP_assoc PF03828.19 EST45194.1 - 1.9 8.8 5.4 34 4.7 1.9 2.8 2 0 0 2 2 2 0 Cid1 family poly A polymerase Myb_DNA-binding PF00249.31 EST45195.1 - 2.4e-16 59.7 0.1 1.7e-10 40.9 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST45195.1 - 8.8e-11 41.9 1.2 8.5e-05 22.7 0.2 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST45195.1 - 8.9e-06 25.5 2.4 2.1e-05 24.3 0.9 2.2 1 1 0 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EST45195.1 - 0.00092 19.4 0.6 0.0025 18.0 0.6 1.7 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DPPIV_rep PF18811.1 EST45195.1 - 0.04 13.9 1.0 0.091 12.7 1.0 1.6 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) low complexity region Carbpep_Y_N PF05388.11 EST45195.1 - 0.95 10.0 5.7 1.8 9.1 0.5 2.3 1 1 0 2 2 2 0 Carboxypeptidase Y pro-peptide RRM_3 PF08777.11 EST45196.1 - 0.12 12.4 0.0 0.55 10.3 0.0 2.0 2 0 0 2 2 2 0 RNA binding motif Sld5 PF05916.11 EST45198.1 - 1.3e-05 25.6 1.9 1.8e-05 25.1 1.9 1.2 1 0 0 1 1 1 1 GINS complex protein DUF4168 PF13767.6 EST45199.1 - 0.016 16.4 7.8 0.016 16.4 7.8 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4168) HSCB_C PF07743.13 EST45199.1 - 0.016 15.7 4.4 0.22 12.0 0.2 3.0 2 2 0 2 2 2 0 HSCB C-terminal oligomerisation domain CENP-O PF09496.10 EST45199.1 - 0.21 11.5 11.9 0.31 11.0 11.7 1.3 1 1 0 1 1 1 0 Cenp-O kinetochore centromere component Arm-DNA-bind_2 PF12167.8 EST45199.1 - 0.41 10.6 2.6 1.3 9.0 0.2 2.8 2 0 0 2 2 2 0 Arm DNA-binding domain TipAS PF07739.13 EST45199.1 - 0.62 10.6 5.2 0.35 11.4 1.5 2.2 1 1 2 3 3 3 0 TipAS antibiotic-recognition domain CENP-Q PF13094.6 EST45199.1 - 2.5 8.3 9.8 0.48 10.6 5.8 1.8 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit PP2C PF00481.21 EST45200.1 - 6.3e-28 98.1 0.1 8.8e-27 94.4 0.0 2.0 2 0 0 2 2 2 1 Protein phosphatase 2C Tyr_Deacylase PF02580.16 EST45200.1 - 0.0043 17.6 0.2 0.0079 16.7 0.2 1.3 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Ank_2 PF12796.7 EST45201.1 - 2.9e-14 53.4 6.3 1e-06 29.2 0.2 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EST45201.1 - 0.0059 17.0 0.1 37 5.3 0.0 4.5 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 EST45201.1 - 0.0086 16.4 0.0 0.099 13.0 0.0 2.7 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EST45201.1 - 0.029 15.0 0.1 5.3 7.7 0.0 3.6 2 1 0 2 2 2 0 Ankyrin repeats (many copies) RepB-RCR_reg PF10723.9 EST45203.1 - 0.03 14.3 0.1 0.081 12.9 0.1 1.7 1 0 0 1 1 1 0 Replication regulatory protein RepB Gp_dh_C PF02800.20 EST45203.1 - 0.056 13.0 0.3 0.23 11.0 0.1 2.0 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain YpsA PF06908.11 EST45204.1 - 0.0038 17.2 0.4 0.0054 16.7 0.4 1.3 1 0 0 1 1 1 1 YspA SLOG family WGG PF10273.9 EST45204.1 - 0.037 14.7 0.9 0.11 13.1 0.9 1.9 1 1 0 1 1 1 0 Pre-rRNA-processing protein TSR2 ArsR PF09824.9 EST45204.1 - 0.14 11.7 3.3 0.74 9.4 0.1 2.3 2 1 0 2 2 2 0 ArsR transcriptional regulator Pkinase PF00069.25 EST45205.1 - 1.1e-60 205.2 0.4 1.3e-60 205.1 0.4 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST45205.1 - 1.4e-29 103.2 0.1 1.7e-29 102.9 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EST45205.1 - 1.6e-07 30.9 0.2 3.1e-07 30.0 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EST45205.1 - 1.4e-05 24.5 0.4 0.0029 17.0 0.1 2.3 1 1 1 2 2 2 2 Kinase-like APH PF01636.23 EST45205.1 - 0.00011 22.2 0.0 0.00021 21.3 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EST45205.1 - 0.00018 21.1 0.3 0.00028 20.6 0.3 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 EST45205.1 - 0.0007 18.5 0.1 0.001 18.0 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EST45205.1 - 0.0037 16.9 0.8 0.01 15.5 0.7 1.9 1 1 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 EST45205.1 - 0.009 15.6 1.2 0.012 15.2 0.2 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase TUG-UBL1 PF11470.8 EST45207.1 - 0.014 15.6 0.7 0.062 13.5 0.7 2.2 1 0 0 1 1 1 0 TUG ubiquitin-like domain Band_7 PF01145.25 EST45209.1 - 1.9e-19 70.4 0.0 4.8e-19 69.1 0.0 1.7 1 1 0 1 1 1 1 SPFH domain / Band 7 family zf-rbx1 PF12678.7 EST45210.1 - 3.6e-14 52.8 17.0 4.4e-14 52.5 17.0 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EST45210.1 - 1.7e-10 40.8 9.7 2e-10 40.6 9.7 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 EST45210.1 - 2.3e-06 27.3 17.2 3.3e-06 26.8 4.1 2.2 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EST45210.1 - 2.4e-05 24.6 20.8 0.00029 21.1 20.8 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EST45210.1 - 0.00075 19.3 16.5 0.07 13.0 16.5 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EST45210.1 - 0.014 15.4 12.9 0.036 14.1 12.9 1.9 1 1 0 1 1 1 0 RING-type zinc-finger ADK_lid PF05191.14 EST45210.1 - 0.03 14.3 5.8 0.5 10.4 0.9 2.5 2 1 0 2 2 2 0 Adenylate kinase, active site lid zf-C3HC4_4 PF15227.6 EST45210.1 - 0.045 13.9 3.5 0.045 13.9 3.5 2.9 1 1 2 3 3 3 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 EST45210.1 - 0.096 12.8 5.4 0.096 12.8 5.4 3.1 2 1 0 2 2 1 0 RING-variant domain zf-RING_5 PF14634.6 EST45210.1 - 0.6 10.1 20.5 17 5.5 20.5 2.4 1 1 0 1 1 1 0 zinc-RING finger domain FANCL_C PF11793.8 EST45210.1 - 0.79 9.9 15.7 0.41 10.9 12.1 2.2 1 1 1 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 EST45210.1 - 2.1 8.1 21.2 26 4.5 19.2 2.8 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 EST45210.1 - 3.4 7.6 19.1 39 4.2 14.5 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Abhydrolase_6 PF12697.7 EST45211.1 - 5.6e-16 59.8 0.0 7.1e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EST45211.1 - 9.6e-13 47.9 0.0 1.5e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EST45211.1 - 1.6e-06 28.0 0.0 8.6e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.20 EST45211.1 - 3.1e-06 27.5 0.0 6e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.25 EST45211.1 - 0.00084 19.2 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.7 EST45211.1 - 0.007 16.1 0.0 0.02 14.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.13 EST45211.1 - 0.021 13.3 0.4 0.39 9.2 0.0 2.5 3 0 0 3 3 3 0 Platelet-activating factor acetylhydrolase, isoform II SDA1 PF05285.12 EST45212.1 - 1.7e-11 44.2 54.0 6e-07 29.2 24.6 3.5 2 1 1 3 3 3 2 SDA1 SAP18 PF06487.12 EST45212.1 - 3 8.0 9.0 16 5.6 0.1 4.1 3 2 0 3 3 3 0 Sin3 associated polypeptide p18 (SAP18) Bromodomain PF00439.25 EST45213.1 - 1.3e-13 50.8 0.1 3.4e-13 49.5 0.1 1.7 1 0 0 1 1 1 1 Bromodomain Pkinase PF00069.25 EST45214.1 - 1.5e-37 129.4 4.9 9.7e-35 120.2 4.7 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST45214.1 - 1.5e-20 73.5 0.3 1e-14 54.5 0.1 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EST45214.1 - 3.8e-05 23.2 1.9 0.00038 19.9 0.0 3.0 3 1 0 3 3 3 1 Kinase-like 7TM_GPCR_Srab PF10292.9 EST45215.1 - 2.6 6.9 11.6 0.96 8.3 2.5 2.1 1 1 1 2 2 2 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor Ead_Ea22 PF13935.6 EST45216.1 - 0.028 15.1 0.0 0.042 14.5 0.0 1.2 1 0 0 1 1 1 0 Ead/Ea22-like protein Dpy-30 PF05186.13 EST45217.1 - 3.2e-17 61.9 0.1 3.6e-17 61.8 0.1 1.1 1 0 0 1 1 1 1 Dpy-30 motif RIIa PF02197.17 EST45217.1 - 0.0034 17.0 0.0 0.0053 16.4 0.0 1.3 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit DUF5582 PF17819.1 EST45217.1 - 0.075 13.5 0.0 0.076 13.5 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5582) T2SSG PF08334.11 EST45217.1 - 0.087 12.9 0.1 0.097 12.7 0.1 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein G zf-UBR PF02207.20 EST45218.1 - 1.7e-11 44.1 11.1 1.7e-11 44.1 11.1 3.8 4 1 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) CdiI_4 PF18624.1 EST45218.1 - 0.01 16.3 4.9 0.012 16.1 1.1 3.1 2 0 0 2 2 2 0 CDI immunity protein NCE101 PF11654.8 EST45218.1 - 0.15 11.8 0.1 0.51 10.1 0.1 1.9 1 0 0 1 1 1 0 Non-classical export protein 1 AMP-binding PF00501.28 EST45219.1 - 1.4e-64 218.3 0.0 3.4e-64 217.0 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme Ribosomal_L24e PF01246.20 EST45222.1 - 1.9e-28 98.5 2.8 3.9e-28 97.5 2.8 1.5 1 0 0 1 1 1 1 Ribosomal protein L24e zf-FCS PF06467.14 EST45222.1 - 0.025 14.5 3.3 0.047 13.6 3.3 1.4 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif DUF3220 PF11516.8 EST45222.1 - 0.031 14.5 0.1 0.078 13.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3120) DUF2175 PF09943.9 EST45222.1 - 0.038 14.3 1.9 0.086 13.1 0.2 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) PHP PF02811.19 EST45224.1 - 2.8e-10 40.7 0.3 4.7e-10 40.0 0.3 1.4 1 0 0 1 1 1 1 PHP domain Ank_2 PF12796.7 EST45225.1 - 0.0038 17.8 0.0 0.27 11.9 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EST45225.1 - 0.018 15.5 0.0 5.1 8.0 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeat TTL PF03133.15 EST45227.1 - 8.2e-49 166.3 3.7 1.1e-48 165.9 3.7 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EST45227.1 - 2.7e-05 23.5 0.1 0.00035 19.9 0.0 2.3 2 1 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EST45227.1 - 0.042 13.1 0.0 0.11 11.8 0.0 1.8 1 1 0 1 1 1 0 Sugar-transfer associated ATP-grasp RimK PF08443.11 EST45227.1 - 0.074 12.6 0.3 1.4 8.5 0.0 2.7 2 1 1 3 3 3 0 RimK-like ATP-grasp domain MLD PF11647.8 EST45228.1 - 2.3 8.6 7.2 0.69 10.2 1.0 2.8 2 1 1 3 3 3 0 Membrane Localization Domain UQ_con PF00179.26 EST45231.1 - 1.4e-32 112.3 0.5 1.5e-32 112.1 0.5 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EST45231.1 - 0.011 16.0 0.5 0.017 15.4 0.5 1.4 1 1 0 1 1 1 0 RWD domain UQ_con PF00179.26 EST45232.1 - 4.4e-52 175.5 0.0 4.9e-52 175.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EST45232.1 - 0.00077 19.7 0.1 0.0011 19.3 0.1 1.4 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 EST45232.1 - 0.016 14.9 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B zf-UBR PF02207.20 EST45233.1 - 2.9e-10 40.2 13.6 2.9e-10 40.2 13.6 2.8 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) Lactamase_B_2 PF12706.7 EST45234.1 - 2e-08 34.0 0.0 4.4e-08 32.9 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EST45234.1 - 7.2e-07 29.4 0.0 2.2e-06 27.8 0.0 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily WSN PF02206.18 EST45234.1 - 0.0096 15.8 0.4 0.03 14.2 0.2 2.0 1 1 0 1 1 1 1 Domain of unknown function Ala_racemase_N PF01168.20 EST45235.1 - 5.3e-17 62.2 0.0 6.4e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DUF775 PF05603.12 EST45235.1 - 0.005 16.4 2.2 0.0082 15.7 2.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF775) Orn_Arg_deC_N PF02784.16 EST45235.1 - 0.085 12.2 0.5 0.29 10.5 0.5 1.8 1 1 0 1 1 1 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Peptidase_A6 PF01829.16 EST45235.1 - 0.12 11.6 0.1 0.15 11.3 0.1 1.1 1 0 0 1 1 1 0 Peptidase A6 family MetallophosN PF16371.5 EST45236.1 - 0.17 12.2 0.4 19 5.6 0.0 2.5 2 0 0 2 2 2 0 N terminal of Calcineurin-like phosphoesterase Pkinase PF00069.25 EST45237.1 - 3.5e-57 193.8 0.0 4e-57 193.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST45237.1 - 1.3e-29 103.3 0.0 1.9e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EST45237.1 - 0.0065 15.4 0.1 0.0095 14.9 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EST45237.1 - 0.041 13.8 0.0 0.058 13.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EST45237.1 - 0.059 12.7 0.1 0.086 12.2 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 EST45237.1 - 0.11 12.6 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 ABC1 family DUF2157 PF09925.9 EST45238.1 - 0.17 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) SHIPPO-rpt PF07004.12 EST45238.1 - 0.22 12.5 5.4 40 5.4 0.1 4.5 2 1 2 4 4 4 0 Sperm-tail PG-rich repeat DUF3600 PF12207.8 EST45238.1 - 0.3 11.0 3.4 0.46 10.4 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3600) Nucleoporin_FG PF13634.6 EST45238.1 - 4.6 8.1 25.5 1.5 9.7 9.9 3.0 1 1 1 2 2 2 0 Nucleoporin FG repeat region MIEAP PF16026.5 EST45239.1 - 0.31 11.2 9.9 0.028 14.6 4.6 1.8 1 1 1 2 2 2 0 Mitochondria-eating protein LRR_4 PF12799.7 EST45240.1 - 3.4e-12 46.4 11.6 3e-07 30.6 1.9 3.1 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EST45240.1 - 4e-07 29.7 2.1 5.3e-07 29.3 2.1 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 EST45240.1 - 2.5e-05 24.0 10.5 0.011 15.4 0.7 2.9 2 1 0 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 EST45240.1 - 0.14 12.3 10.7 12 6.2 0.0 4.7 5 0 0 5 5 5 0 Leucine Rich repeat N_Asn_amidohyd PF14736.6 EST45243.1 - 0.034 13.3 0.4 0.046 12.9 0.4 1.3 1 0 0 1 1 1 0 Protein N-terminal asparagine amidohydrolase DUF5585 PF17823.1 EST45243.1 - 0.11 11.4 3.1 0.14 11.1 3.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5585) Ribosomal_L50 PF10501.9 EST45245.1 - 0.012 15.8 1.5 0.015 15.5 1.5 1.3 1 0 0 1 1 1 0 Ribosomal subunit 39S PRP9_N PF16958.5 EST45245.1 - 0.043 13.8 11.7 0.051 13.6 11.7 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor PRP9 N-terminus LRR_4 PF12799.7 EST45248.1 - 1e-07 32.1 15.2 4.2e-05 23.8 2.1 3.4 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EST45248.1 - 3.5e-07 29.9 7.3 0.00015 21.4 0.8 2.7 2 0 0 2 2 2 2 Leucine rich repeat LRR_9 PF14580.6 EST45248.1 - 4.2e-07 29.6 3.3 6.2e-07 29.1 3.3 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 EST45248.1 - 0.0062 16.5 7.6 2.1 8.6 0.1 4.0 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 EST45248.1 - 0.86 10.4 5.1 41 5.3 1.1 3.8 2 2 0 2 2 2 0 Leucine Rich Repeat 4HBT_2 PF13279.6 EST45251.1 - 0.21 12.1 1.8 0.3 11.6 0.6 1.8 2 0 0 2 2 2 0 Thioesterase-like superfamily Abhydrolase_1 PF00561.20 EST45253.1 - 3.1e-15 56.5 0.7 2.1e-12 47.2 0.2 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EST45253.1 - 2.6e-14 53.1 0.0 6.1e-14 51.9 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EST45253.1 - 4.4e-14 53.6 0.0 5.6e-14 53.3 0.0 1.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.12 EST45253.1 - 0.00091 19.2 3.0 0.02 14.8 3.0 2.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0227) Thioesterase PF00975.20 EST45253.1 - 0.0079 16.3 0.1 0.015 15.4 0.1 1.5 1 0 0 1 1 1 1 Thioesterase domain DUF915 PF06028.11 EST45253.1 - 0.011 15.1 2.8 0.032 13.5 0.1 2.7 2 1 1 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) PDU_like PF15953.5 EST45253.1 - 0.021 14.9 1.3 0.12 12.5 0.1 2.4 1 1 1 2 2 2 0 Putative propanediol utilisation DUF1057 PF06342.12 EST45253.1 - 0.024 13.7 2.0 0.042 12.9 1.3 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Rsbr_N PF08678.10 EST45253.1 - 0.03 14.4 1.9 0.08 13.0 0.4 2.1 2 0 0 2 2 2 0 Rsbr N terminal Palm_thioest PF02089.15 EST45253.1 - 0.032 14.1 0.1 0.073 12.9 0.1 1.8 1 1 1 2 2 2 0 Palmitoyl protein thioesterase PGAP1 PF07819.13 EST45253.1 - 0.034 13.9 0.7 0.12 12.1 0.2 2.0 1 1 1 2 2 2 0 PGAP1-like protein Fn3_assoc PF13287.6 EST45255.1 - 1.6 9.0 4.5 5.3 7.3 0.3 2.9 2 1 1 3 3 3 0 Fn3 associated Slx4 PF09494.10 EST45257.1 - 0.01 15.8 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Slx4 endonuclease Cpn60_TCP1 PF00118.24 EST45258.1 - 7.6e-49 166.6 4.8 1.5e-28 99.7 2.3 2.1 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family P2_N PF18628.1 EST45258.1 - 0.016 14.9 0.2 0.046 13.5 0.2 1.7 1 0 0 1 1 1 0 Viral coat protein P2 N-terminal domain tRNA-synt_1d PF00750.19 EST45258.1 - 0.039 12.9 0.1 0.067 12.1 0.1 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (R) Pyr_redox_2 PF07992.14 EST45259.1 - 3.8e-52 177.4 1.2 4.3e-52 177.2 1.2 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EST45259.1 - 2.7e-22 79.4 6.9 8.8e-19 67.9 0.1 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EST45259.1 - 3.4e-18 66.0 2.6 1.8e-16 60.4 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EST45259.1 - 6.1e-06 25.8 0.2 0.00018 21.0 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EST45259.1 - 0.00021 20.1 0.9 0.2 10.3 0.7 3.0 3 0 0 3 3 3 2 HI0933-like protein FAD_binding_2 PF00890.24 EST45259.1 - 0.0011 18.2 4.8 0.016 14.3 1.2 3.0 2 1 0 3 3 3 1 FAD binding domain GIDA PF01134.22 EST45259.1 - 0.0018 17.4 9.8 0.13 11.3 1.4 4.1 3 2 1 4 4 4 1 Glucose inhibited division protein A K_oxygenase PF13434.6 EST45259.1 - 0.002 17.3 0.5 0.88 8.6 0.0 2.9 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 EST45259.1 - 0.01 16.3 1.0 0.044 14.2 0.0 2.4 2 1 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_8 PF13450.6 EST45259.1 - 0.012 15.9 0.2 0.044 14.0 0.1 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EST45259.1 - 0.043 13.0 1.9 0.28 10.4 0.3 2.4 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.20 EST45259.1 - 0.16 12.0 0.3 1.1 9.3 0.1 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 EST45259.1 - 0.57 9.7 14.2 1.2 8.6 0.0 3.5 2 2 1 4 4 4 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EST45259.1 - 0.93 9.5 4.1 23 4.9 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding zf-B_box PF00643.24 EST45261.1 - 0.012 15.8 2.1 0.019 15.1 0.2 2.0 2 0 0 2 2 2 0 B-box zinc finger FYVE_2 PF02318.16 EST45261.1 - 0.017 15.3 2.9 0.02 15.1 2.9 1.0 1 0 0 1 1 1 0 FYVE-type zinc finger CEBP_ZZ PF16366.5 EST45261.1 - 0.12 12.6 4.2 3.2 8.1 0.4 2.0 1 1 1 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain DUF674 PF05056.12 EST45261.1 - 0.23 10.3 2.5 0.22 10.3 2.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF674) Med29 PF11568.8 EST45263.1 - 0.017 15.3 1.7 1.5 9.0 0.1 2.1 1 1 1 2 2 2 0 Mediator complex subunit 29 Fic_N PF13784.6 EST45263.1 - 0.068 13.2 0.0 0.26 11.4 0.0 1.8 2 0 0 2 2 2 0 Fic/DOC family N-terminal PNP_UDP_1 PF01048.20 EST45264.1 - 3.9e-43 147.4 1.2 4.3e-43 147.2 1.2 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily LRR_4 PF12799.7 EST45265.1 - 0.00016 22.0 17.7 0.0018 18.6 8.3 3.3 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EST45265.1 - 0.00025 20.7 9.5 0.0083 15.9 4.1 3.3 1 1 2 3 3 3 2 Leucine rich repeat FTH PF01827.27 EST45265.1 - 0.2 11.4 6.4 0.23 11.3 5.6 1.5 1 1 0 1 1 1 0 FTH domain LRR_6 PF13516.6 EST45265.1 - 0.66 10.2 3.9 20 5.6 0.0 3.6 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 EST45265.1 - 5.9 7.9 9.9 12 6.9 1.1 4.0 3 1 0 3 3 3 0 Leucine Rich Repeat Helicase_C PF00271.31 EST45267.1 - 1.1e-14 54.7 2.5 1.1e-14 54.7 2.5 2.5 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_14 PF13173.6 EST45267.1 - 4e-05 23.6 1.6 0.00015 21.8 0.3 2.7 1 1 1 2 2 2 1 AAA domain HA2 PF04408.23 EST45267.1 - 5.5e-05 23.4 0.0 0.00014 22.1 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) AAA_30 PF13604.6 EST45267.1 - 0.00021 21.0 0.0 0.00037 20.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EST45267.1 - 0.00036 20.0 6.1 0.028 13.9 0.3 3.2 2 1 0 3 3 3 2 PhoH-like protein ResIII PF04851.15 EST45267.1 - 0.00068 19.7 0.4 0.00068 19.7 0.4 4.5 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EST45267.1 - 0.0008 19.2 1.4 0.025 14.3 1.1 3.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 EST45267.1 - 0.0027 16.8 0.1 0.11 11.6 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein EF-hand_1 PF00036.32 EST45269.1 - 5.4e-20 69.4 2.5 1e-05 24.7 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EST45269.1 - 2.1e-17 61.5 0.3 5.7e-05 22.7 0.0 4.3 4 1 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 EST45269.1 - 2.2e-15 55.4 2.8 6.1e-05 22.3 0.0 3.9 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 EST45269.1 - 3.3e-14 53.1 0.6 5.4e-10 39.6 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EST45269.1 - 6.3e-08 32.3 3.5 0.01 15.7 0.0 4.1 2 1 3 5 5 5 3 EF-hand domain pair EF-hand_10 PF14788.6 EST45269.1 - 9.2e-05 22.2 0.5 0.21 11.5 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.7 EST45269.1 - 0.0016 18.4 0.4 0.039 13.9 0.1 2.3 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EST45269.1 - 0.011 16.0 0.0 2.3 8.6 0.0 2.5 2 2 0 2 2 2 0 EF-hand domain GAGA_bind PF06217.12 EST45270.1 - 0.09 13.0 5.3 0.11 12.7 5.3 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Seryl_tRNA_N PF02403.22 EST45270.1 - 0.34 11.1 20.5 0.65 10.2 20.5 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DASH_Spc19 PF08287.11 EST45270.1 - 3.1 7.7 19.7 0.34 10.8 15.0 1.7 2 0 0 2 2 2 0 Spc19 zf-RING_2 PF13639.6 EST45271.1 - 6.1e-09 36.1 3.3 6.1e-09 36.1 3.3 5.1 4 1 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 EST45271.1 - 3.4e-06 26.8 4.6 3.4e-06 26.8 4.6 5.4 4 1 3 7 7 7 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EST45271.1 - 7.2e-06 25.9 3.8 7.2e-06 25.9 3.8 5.9 5 1 0 5 5 5 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EST45271.1 - 3.1e-05 23.7 3.1 3.1e-05 23.7 3.1 5.5 3 1 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-CHY PF05495.12 EST45271.1 - 9.4e-05 22.8 25.0 9.4e-05 22.8 25.0 4.1 3 1 0 3 3 3 1 CHY zinc finger zf-CHY PF05495.12 EST45273.1 - 2.9e-07 30.9 25.1 2.9e-07 30.9 25.1 4.6 3 1 0 3 3 3 1 CHY zinc finger zf-C3HC4_3 PF13920.6 EST45273.1 - 2e-06 27.6 8.6 2e-06 27.6 8.6 5.2 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EST45273.1 - 3.2e-06 26.9 10.9 3.2e-06 26.9 10.9 5.4 4 2 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EST45273.1 - 1.6e-05 24.8 10.4 1.6e-05 24.8 10.4 6.3 4 2 1 5 5 5 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EST45273.1 - 2.4e-05 24.1 9.9 2.4e-05 24.1 9.9 4.8 4 2 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) Topoisom_I_N PF02919.15 EST45273.1 - 0.048 13.2 1.4 0.1 12.1 1.4 1.5 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Abhydrolase_1 PF00561.20 EST45277.1 - 3e-11 43.5 0.1 5.4e-11 42.6 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EST45277.1 - 1.2e-09 39.1 0.0 1.5e-09 38.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EST45277.1 - 1.3e-09 37.7 0.0 7.7e-09 35.2 0.0 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 UPF0227 PF05728.12 EST45277.1 - 0.00017 21.6 3.9 0.0035 17.3 3.9 2.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0227) Thioesterase PF00975.20 EST45277.1 - 0.00039 20.6 0.0 0.0005 20.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain LIDHydrolase PF10230.9 EST45277.1 - 0.0043 16.7 0.3 0.0062 16.1 0.3 1.5 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Ndr PF03096.14 EST45277.1 - 0.0044 15.8 0.1 0.0062 15.3 0.1 1.3 1 0 0 1 1 1 1 Ndr family DUF915 PF06028.11 EST45277.1 - 0.0064 15.9 3.9 0.015 14.7 0.3 2.7 2 1 1 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.13 EST45277.1 - 0.016 14.9 1.1 0.044 13.5 0.4 1.9 1 1 0 1 1 1 0 PGAP1-like protein SE PF08491.10 EST45277.1 - 0.021 13.9 0.4 0.032 13.3 0.4 1.2 1 0 0 1 1 1 0 Squalene epoxidase Abhydrolase_5 PF12695.7 EST45277.1 - 0.024 14.4 0.2 0.13 12.0 0.0 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 EST45277.1 - 0.17 11.7 0.0 0.26 11.1 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold FAD_binding_8 PF08022.12 EST45277.1 - 0.5 10.5 2.8 0.48 10.5 0.9 2.0 2 0 0 2 2 2 0 FAD-binding domain LRR_4 PF12799.7 EST45278.1 - 1.1e-08 35.3 8.3 0.00083 19.7 0.7 3.4 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EST45278.1 - 2e-07 30.6 4.3 0.016 14.9 0.0 3.5 2 2 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 EST45278.1 - 8.7e-06 25.6 7.1 0.071 13.7 0.2 4.5 3 2 0 3 3 3 2 Leucine Rich Repeat LRRNT_2 PF08263.12 EST45278.1 - 5.2e-05 23.5 5.8 0.00013 22.2 5.8 1.7 1 1 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 EST45278.1 - 0.0039 17.1 6.2 0.4 10.8 0.1 4.2 5 0 0 5 5 5 2 Leucine Rich repeat DUF4780 PF16012.5 EST45278.1 - 0.052 13.0 0.3 0.11 12.0 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4780) DUF2213 PF09979.9 EST45278.1 - 0.057 13.4 0.0 0.085 12.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2213) Aminotran_1_2 PF00155.21 EST45279.1 - 1.3e-38 133.1 0.0 1.9e-38 132.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Complex1_LYR PF05347.15 EST45280.1 - 0.027 14.5 0.3 5.2 7.2 0.0 2.8 2 1 0 2 2 2 0 Complex 1 protein (LYR family) Cnn_1N PF07989.11 EST45280.1 - 0.035 14.3 5.5 0.035 14.3 5.5 3.0 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 DUF4795 PF16043.5 EST45280.1 - 0.15 11.6 14.5 0.21 11.2 14.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) LMBR1 PF04791.16 EST45280.1 - 1.6 7.6 6.2 2.2 7.1 6.2 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein DHR10 PF18595.1 EST45280.1 - 1.8 8.6 18.6 0.059 13.4 5.6 2.8 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain Dapper PF15268.6 EST45280.1 - 2.5 6.9 9.2 2.8 6.7 9.2 1.0 1 0 0 1 1 1 0 Dapper TSC22 PF01166.18 EST45280.1 - 4 7.8 18.9 1 9.7 5.4 3.6 2 1 2 4 4 4 0 TSC-22/dip/bun family GrpE PF01025.19 EST45280.1 - 4.1 7.0 17.8 2.9 7.5 7.3 2.5 1 1 1 2 2 2 0 GrpE Seryl_tRNA_N PF02403.22 EST45280.1 - 4.9 7.4 14.6 1.1 9.6 9.7 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DivIVA PF05103.13 EST45280.1 - 6.4 6.9 25.0 1.4e+02 2.5 25.0 2.4 1 1 0 1 1 1 0 DivIVA protein CENP-H PF05837.12 EST45280.1 - 6.4 7.2 19.1 4.3 7.8 9.2 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Sybindin PF04099.12 EST45281.1 - 3.7e-20 72.3 0.1 4.2e-20 72.1 0.1 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 EST45281.1 - 0.011 15.9 0.2 0.017 15.2 0.2 1.3 1 1 0 1 1 1 0 Sedlin, N-terminal conserved region Pkinase PF00069.25 EST45283.1 - 2.1e-53 181.4 0.5 3.3e-53 180.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST45283.1 - 5.9e-43 147.0 0.1 1.1e-42 146.1 0.1 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EST45283.1 - 0.001 18.0 0.0 0.0019 17.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EST45283.1 - 0.0018 17.6 0.0 0.006 15.9 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EST45283.1 - 0.012 14.9 0.1 0.042 13.2 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family YabA PF06156.13 EST45283.1 - 0.049 14.3 1.6 0.049 14.3 1.6 2.2 3 0 0 3 3 3 0 Initiation control protein YabA ZapB PF06005.12 EST45283.1 - 0.14 12.6 9.1 0.051 14.0 5.4 2.2 2 0 0 2 2 2 0 Cell division protein ZapB bZIP_1 PF00170.21 EST45283.1 - 0.15 12.2 2.4 0.44 10.7 2.4 1.8 1 0 0 1 1 1 0 bZIP transcription factor PRKG1_interact PF15898.5 EST45283.1 - 0.15 12.9 5.2 2.9 8.8 0.2 3.0 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain UBA_4 PF14555.6 EST45285.1 - 4.8e-07 29.5 0.0 8.3e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain SR-25 PF10500.9 EST45286.1 - 8.4 5.9 7.8 20 4.7 7.8 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AAA_12 PF13087.6 EST45287.1 - 2.7e-35 121.8 0.8 2.7e-35 121.8 0.8 3.6 4 0 0 4 4 4 1 AAA domain AAA_11 PF13086.6 EST45287.1 - 5.2e-19 69.1 0.1 5.6e-09 36.2 0.2 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EST45287.1 - 1.6e-13 51.2 0.0 6e-13 49.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EST45287.1 - 3.3e-11 43.3 0.0 5e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EST45287.1 - 1.2e-08 35.0 1.2 9.8e-05 22.2 0.2 3.8 2 1 1 3 3 3 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 EST45287.1 - 9.2e-06 25.1 0.6 4.3e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DUF2439 PF10382.9 EST45287.1 - 9e-05 22.7 2.7 9e-05 22.7 2.7 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF2439) Helicase_RecD PF05127.14 EST45287.1 - 9.5e-05 22.3 0.0 0.00032 20.6 0.0 2.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 EST45287.1 - 0.1 12.4 0.2 4.1 7.3 0.0 2.7 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain SHIPPO-rpt PF07004.12 EST45288.1 - 0.012 16.5 2.6 1.8 9.6 0.1 3.8 4 0 0 4 4 4 0 Sperm-tail PG-rich repeat DUF3418 PF11898.8 EST45289.1 - 0.0032 16.2 0.8 0.0035 16.1 0.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3418) PriA_C PF18074.1 EST45289.1 - 0.011 16.5 2.1 0.085 13.7 0.3 2.3 2 1 1 3 3 3 0 Primosomal protein N C-terminal domain Bromodomain PF00439.25 EST45289.1 - 0.025 14.7 0.2 0.045 13.8 0.2 1.4 1 0 0 1 1 1 0 Bromodomain DUF5524 PF17662.1 EST45290.1 - 0.037 13.4 0.1 0.14 11.5 0.1 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5524) Nkap_C PF06047.11 EST45290.1 - 0.071 13.2 0.1 0.34 11.0 0.1 1.9 2 0 0 2 2 2 0 NF-kappa-B-activating protein C-terminal domain LptE PF04390.12 EST45291.1 - 1.4 9.7 4.0 52 4.6 0.0 3.6 3 0 0 3 3 3 0 Lipopolysaccharide-assembly vATP-synt_E PF01991.18 EST45292.1 - 1.6e-14 53.8 12.1 2.6e-14 53.1 12.1 1.3 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit U3_snoRNA_assoc PF08297.11 EST45292.1 - 0.13 12.9 3.4 0.27 12.0 3.4 1.5 1 0 0 1 1 1 0 U3 snoRNA associated Myb_DNA-binding PF00249.31 EST45293.1 - 2.1e-15 56.6 2.4 3.3e-09 36.8 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST45293.1 - 3e-15 56.2 6.7 5e-07 29.9 0.7 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST45293.1 - 6.2e-05 22.8 1.6 0.00024 20.9 0.2 2.3 2 0 0 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EST45293.1 - 0.00024 21.2 1.4 0.0054 16.9 0.1 2.5 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 EST45293.1 - 0.0057 16.7 0.6 0.34 11.0 0.3 3.1 1 1 1 2 2 2 1 SLIDE Peptidase_M3_N PF08439.10 EST45293.1 - 0.022 15.0 0.0 0.055 13.7 0.0 1.7 1 0 0 1 1 1 0 Oligopeptidase F E7R PF17467.2 EST45293.1 - 0.13 12.4 0.5 1.5 9.0 0.1 2.3 2 0 0 2 2 2 0 Viral Protein E7 Myb_DNA-bind_4 PF13837.6 EST45293.1 - 0.14 12.5 11.2 0.27 11.6 3.7 3.4 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 EST45293.1 - 0.19 11.8 7.0 2.1 8.5 0.5 3.1 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain Phage_lysozyme2 PF18013.1 EST45293.1 - 0.21 11.6 3.8 6.3 6.8 0.4 2.4 2 0 0 2 2 2 0 Phage tail lysozyme Atg29_N PF18388.1 EST45293.1 - 0.39 10.6 2.1 1.5 8.7 0.2 2.4 2 0 0 2 2 2 0 Atg29 N-terminal domain Phasin_2 PF09361.10 EST45294.1 - 0.023 15.0 0.9 2.6 8.4 0.3 3.0 2 0 0 2 2 2 0 Phasin protein Fer4_24 PF18109.1 EST45294.1 - 0.85 9.9 7.4 1 9.7 0.1 3.8 3 0 0 3 3 3 0 Ferredoxin I 4Fe-4S cluster domain CH_2 PF06294.11 EST45295.1 - 4.2e-27 94.1 0.2 7.6e-27 93.3 0.2 1.4 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 EST45295.1 - 6.3e-11 42.0 0.0 1.1e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain DUF2387 PF09526.10 EST45295.1 - 0.057 13.6 0.2 0.16 12.1 0.2 1.8 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) YchF-GTPase_C PF06071.13 EST45295.1 - 0.1 12.8 0.3 0.41 10.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF933) Acetyltransf_11 PF13720.6 EST45296.1 - 5.4 7.5 7.0 2.4 8.7 0.5 4.0 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Pkinase PF00069.25 EST45297.1 - 1.3e-26 93.6 5.2 2e-26 93.0 5.2 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST45297.1 - 7.8e-09 35.2 1.1 1.2e-07 31.3 1.1 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EST45297.1 - 0.0038 16.6 0.0 0.0081 15.5 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EST45297.1 - 0.042 13.8 0.0 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Dehalogenase PF13486.6 EST45297.1 - 0.13 11.6 0.1 0.38 10.1 0.0 1.7 2 0 0 2 2 2 0 Reductive dehalogenase subunit DUF2373 PF10180.9 EST45299.1 - 4.1e-10 39.3 1.5 1e-09 38.1 1.5 1.8 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) GBR_NSP5 PF17580.2 EST45299.1 - 0.1 12.4 4.6 0.059 13.2 2.8 1.6 1 1 0 1 1 1 0 Group B Rotavirus Non-structural protein 5 Shugoshin_N PF07558.11 EST45300.1 - 0.029 14.2 6.0 0.11 12.4 0.0 3.5 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region ETF_QO PF05187.13 EST45300.1 - 0.19 11.9 1.6 5.2 7.3 0.2 2.6 1 1 0 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Inhibitor_Mig-6 PF11555.8 EST45301.1 - 0.029 14.4 0.5 0.068 13.3 0.1 1.9 2 0 0 2 2 2 0 EGFR receptor inhibitor Mig-6 DUF2714 PF10896.8 EST45302.1 - 0.025 14.6 0.2 0.044 13.8 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2714) Ax_dynein_light PF10211.9 EST45304.1 - 0.0073 16.3 10.9 0.011 15.6 10.9 1.3 1 0 0 1 1 1 1 Axonemal dynein light chain FapA PF03961.13 EST45304.1 - 0.0088 14.7 3.2 0.012 14.2 3.2 1.2 1 0 0 1 1 1 1 Flagellar Assembly Protein A APG6_N PF17675.1 EST45304.1 - 0.021 15.4 14.5 0.032 14.7 14.5 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Syntaxin_2 PF14523.6 EST45304.1 - 0.26 11.7 12.4 0.077 13.4 9.1 1.8 2 0 0 2 2 2 0 Syntaxin-like protein Seryl_tRNA_N PF02403.22 EST45304.1 - 0.82 9.9 12.0 1.6 9.0 12.0 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ABC_tran_CTD PF16326.5 EST45304.1 - 1.4 9.2 10.7 23 5.3 10.7 2.3 1 1 0 1 1 1 0 ABC transporter C-terminal domain DivIC PF04977.15 EST45304.1 - 1.9 8.3 13.0 3.1 7.6 10.0 2.3 1 1 1 2 2 2 0 Septum formation initiator DUF1664 PF07889.12 EST45304.1 - 2.1 8.4 5.9 8.1 6.5 2.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SlyX PF04102.12 EST45304.1 - 2.3 8.9 5.5 5.5 7.7 5.5 1.7 1 0 0 1 1 1 0 SlyX DUF4407 PF14362.6 EST45304.1 - 5.5 6.2 6.9 7.7 5.8 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DHHC PF01529.20 EST45305.1 - 2.9e-25 88.9 15.9 2.9e-25 88.9 15.9 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase ZnuA PF01297.17 EST45306.1 - 0.052 12.9 5.4 0.1 12.0 5.4 1.5 1 1 0 1 1 1 0 Zinc-uptake complex component A periplasmic DUF4404 PF14357.6 EST45306.1 - 1.5 9.5 8.6 0.13 12.9 1.4 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) APG6_N PF17675.1 EST45306.1 - 7.1 7.2 13.1 8 7.0 1.4 2.8 1 1 1 2 2 2 0 Apg6 coiled-coil region COG5 PF10392.9 EST45306.1 - 8 6.6 12.5 2.2 8.5 1.7 2.5 2 1 0 2 2 2 0 Golgi transport complex subunit 5 LIAS_N PF16881.5 EST45307.1 - 0.4 11.1 3.9 0.37 11.2 0.4 2.7 2 1 1 3 3 3 0 N-terminal domain of lipoyl synthase of Radical_SAM family DNA_pol_B PF00136.21 EST45309.1 - 2.8e-84 283.5 0.2 2.8e-84 283.5 0.2 2.5 3 0 0 3 3 3 1 DNA polymerase family B zf-DNA_Pol PF08996.10 EST45309.1 - 2.4e-08 33.9 2.9 1e-07 31.9 2.9 2.2 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger Glyco_trans_4_2 PF13477.6 EST45309.1 - 0.017 15.2 0.0 0.053 13.6 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferase 4-like DUF4678 PF15727.5 EST45309.1 - 0.55 9.4 8.5 1.2 8.4 8.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4678) EMG1 PF03587.14 EST45310.1 - 2.6e-72 242.6 0.5 3e-72 242.4 0.5 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Bac_GH3_C PF18034.1 EST45310.1 - 0.11 12.2 0.1 12 5.7 0.0 2.7 2 1 1 3 3 3 0 Bacterial Glycosyl hydrolase family 3 C-terminal domain LD_cluster3 PF18180.1 EST45311.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 SLOG cluster3 family Pkinase PF00069.25 EST45312.1 - 7.3e-52 176.3 2.1 7.3e-52 176.3 2.1 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST45312.1 - 4.6e-32 111.3 0.5 4.6e-32 111.3 0.5 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EST45312.1 - 1.7e-08 34.2 2.5 1.8e-08 34.1 0.0 2.3 2 2 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EST45312.1 - 0.017 13.9 0.1 0.03 13.1 0.1 1.4 1 0 0 1 1 1 0 Fungal protein kinase DnaI_N PF07319.11 EST45312.1 - 3.1 8.5 12.0 1.9 9.2 2.9 2.9 2 1 0 2 2 2 0 Primosomal protein DnaI N-terminus DUF302 PF03625.14 EST45314.1 - 0.064 13.2 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF302 DUF4686 PF15742.5 EST45316.1 - 0.0033 16.6 18.8 0.0033 16.6 18.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4686) LRR_4 PF12799.7 EST45316.1 - 0.42 11.1 0.1 0.42 11.1 0.1 3.8 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) PKcGMP_CC PF16808.5 EST45316.1 - 1.3 9.0 7.4 0.37 10.7 3.0 2.5 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF641 PF04859.12 EST45316.1 - 3.4 8.0 12.8 0.073 13.4 4.3 2.5 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) PIN_8 PF18476.1 EST45317.1 - 0.018 14.9 2.9 0.024 14.5 2.9 1.1 1 0 0 1 1 1 0 PIN like domain Nsp1_C PF05064.13 EST45317.1 - 0.57 10.0 7.7 0.055 13.3 2.0 2.0 1 1 1 2 2 2 0 Nsp1-like C-terminal region MCM_N PF14551.6 EST45317.1 - 1.4 9.5 7.3 5.2 7.7 2.5 2.5 1 1 1 2 2 2 0 MCM N-terminal domain tRNA-synt_1e PF01406.19 EST45318.1 - 0.13 11.6 4.4 0.066 12.5 1.0 1.8 1 1 1 2 2 2 0 tRNA synthetases class I (C) catalytic domain Sds3 PF08598.11 EST45318.1 - 0.35 10.8 10.7 0.1 12.6 7.6 1.5 1 1 1 2 2 2 0 Sds3-like Got1 PF04178.12 EST45319.1 - 1e-12 48.4 17.1 1.4e-12 48.1 17.1 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family PsbH PF00737.20 EST45319.1 - 0.09 12.5 6.1 6.6 6.5 0.0 2.3 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein DUF4231 PF14015.6 EST45319.1 - 0.93 10.0 3.3 0.32 11.5 0.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF2721 PF11026.8 EST45319.1 - 4.1 7.3 11.7 0.24 11.3 5.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) TTL PF03133.15 EST45320.1 - 5.1e-61 206.4 0.1 6e-59 199.6 0.1 2.3 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 EST45320.1 - 1.5e-07 31.0 0.0 0.00071 18.9 0.0 2.5 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 EST45320.1 - 2.6e-05 23.6 0.0 0.0074 15.6 0.0 3.4 2 2 2 4 4 4 1 YheC/D like ATP-grasp DUF1244 PF06844.11 EST45320.1 - 0.017 15.3 0.0 0.051 13.7 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1244) Npun_R1517 PF18068.1 EST45324.1 - 0.015 15.6 0.3 0.045 14.1 0.3 1.8 1 0 0 1 1 1 0 Npun R1517 DUF89 PF01937.19 EST45324.1 - 0.058 12.3 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF89 HEAT_2 PF13646.6 EST45324.1 - 0.12 12.7 0.0 0.7 10.3 0.0 2.2 2 0 0 2 2 2 0 HEAT repeats Mo25 PF08569.11 EST45325.1 - 1.1e-70 238.6 22.4 1.4e-70 238.3 22.4 1.0 1 0 0 1 1 1 1 Mo25-like DUF5601 PF18151.1 EST45325.1 - 0.028 14.7 2.7 0.43 10.9 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5601) PRC2_HTH_1 PF18118.1 EST45326.1 - 0.79 10.6 5.1 8.2 7.3 5.1 2.5 1 1 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain M16C_assoc PF08367.11 EST45327.1 - 5.1e-30 104.4 11.5 1.2e-29 103.2 11.5 1.7 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 EST45327.1 - 3e-16 60.0 2.2 7.2e-15 55.5 0.8 2.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EST45327.1 - 8.2e-06 25.9 0.3 6.5e-05 22.9 0.1 2.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) RL10P_insert PF17777.1 EST45329.1 - 3e-16 59.2 0.0 6.3e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 EST45329.1 - 1.9e-09 37.5 0.1 3.4e-09 36.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Med25 PF11232.8 EST45329.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 25 PTOV activation and synapsin 2 zf-C3HC4_3 PF13920.6 EST45330.1 - 2.6e-12 46.4 10.0 2.6e-12 46.4 10.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EST45330.1 - 1.2e-05 25.5 12.3 1.2e-05 25.5 12.3 1.7 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 EST45330.1 - 0.0025 17.7 10.8 0.0025 17.7 10.8 1.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zinc_ribbon_2 PF13240.6 EST45330.1 - 0.025 14.3 0.4 0.025 14.3 0.4 2.1 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 EST45330.1 - 0.03 14.3 1.5 0.03 14.3 1.5 2.2 1 1 2 3 3 3 0 Double zinc ribbon zf-C3HC4_2 PF13923.6 EST45330.1 - 0.036 13.9 11.8 0.036 13.9 11.8 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EST45330.1 - 0.53 10.3 14.6 5 7.2 14.6 2.3 1 1 0 1 1 1 0 zinc-RING finger domain zinc_ribbon_15 PF17032.5 EST45330.1 - 3.1 8.6 11.2 13 6.6 11.1 2.0 1 1 0 1 1 1 0 zinc-ribbon family UvrD_C PF13361.6 EST45331.1 - 0.005 16.3 4.6 0.005 16.3 4.6 2.1 1 1 0 2 2 2 1 UvrD-like helicase C-terminal domain RNR_N PF08343.10 EST45331.1 - 0.31 11.1 3.0 3 8.0 0.1 2.8 2 0 0 2 2 2 0 Ribonucleotide reductase N-terminal DUF4283 PF14111.6 EST45332.1 - 0.031 13.8 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4283) RRM_1 PF00076.22 EST45332.1 - 0.068 13.0 0.0 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_9 PF17904.1 EST45332.1 - 0.12 12.8 0.1 0.3 11.5 0.0 1.7 2 0 0 2 2 2 0 FMRP KH0 domain NepR PF18557.1 EST45332.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Anti-sigma factor NepR EF-hand_7 PF13499.6 EST45333.1 - 0.0036 17.7 0.1 0.22 12.0 0.0 2.5 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EST45333.1 - 0.0057 16.5 0.2 1.9 8.6 0.1 2.9 3 0 0 3 3 3 2 EF-hand domain CTP_transf_1 PF01148.20 EST45334.1 - 0.031 14.0 5.3 0.035 13.9 5.3 1.2 1 0 0 1 1 1 0 Cytidylyltransferase family DUF485 PF04341.12 EST45334.1 - 0.11 12.4 0.1 0.11 12.4 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function, DUF485 Virul_fac_BrkB PF03631.15 EST45334.1 - 0.56 9.8 8.8 0.83 9.2 8.8 1.2 1 0 0 1 1 1 0 Virulence factor BrkB PspB PF06667.12 EST45334.1 - 1.2 9.2 5.1 2 8.5 0.0 2.4 2 0 0 2 2 2 0 Phage shock protein B YMF19 PF02326.15 EST45334.1 - 2.9 8.7 8.1 0.53 11.1 1.5 2.4 2 0 0 2 2 2 0 Plant ATP synthase F0 Ribonuc_L-PSP PF01042.21 EST45338.1 - 3.4e-17 62.6 0.0 4.4e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP NTP_transf_5 PF14907.6 EST45339.1 - 0.01 15.5 0.3 0.01 15.5 0.3 2.3 2 2 1 3 3 3 0 Uncharacterised nucleotidyltransferase DUF285 PF03382.14 EST45339.1 - 0.12 12.1 1.7 0.13 12.0 0.2 1.8 2 0 0 2 2 2 0 Mycoplasma protein of unknown function, DUF285 DUF3800 PF12686.7 EST45339.1 - 0.13 12.9 1.7 2.6 8.7 2.3 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) Acyltransferase PF01553.21 EST45340.1 - 7.1e-05 22.4 0.0 0.00013 21.6 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Oleosin PF01277.17 EST45340.1 - 0.00067 19.4 3.1 0.0013 18.4 2.2 1.8 2 0 0 2 2 2 1 Oleosin TMEM232 PF15877.5 EST45340.1 - 0.11 11.5 0.6 0.16 11.0 0.6 1.1 1 0 0 1 1 1 0 Transmembrane protein family 232 XPG_I PF00867.18 EST45341.1 - 2.6e-11 43.7 0.1 1e-10 41.8 0.1 2.1 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EST45341.1 - 1.3e-06 28.8 0.2 1.4e-05 25.5 0.0 2.9 3 1 0 3 3 3 1 XPG N-terminal domain NOD2_WH PF17779.1 EST45341.1 - 0.00097 19.4 0.1 0.81 10.1 0.0 2.6 2 0 0 2 2 2 2 NOD2 winged helix domain CDC73_N PF16050.5 EST45341.1 - 0.011 15.1 0.1 0.019 14.3 0.1 1.3 1 0 0 1 1 1 0 Paf1 complex subunit CDC73 N-terminal RNase_Zc3h12a PF11977.8 EST45341.1 - 0.029 14.1 0.1 0.068 13.0 0.1 1.6 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain Flavi_NS2B PF01002.19 EST45341.1 - 0.14 12.0 0.1 0.29 11.0 0.1 1.5 1 0 0 1 1 1 0 Flavivirus non-structural protein NS2B Gly_kinase PF02595.15 EST45344.1 - 1.1e-77 261.5 0.1 1.3e-77 261.3 0.1 1.0 1 0 0 1 1 1 1 Glycerate kinase family CPSase_L_D2 PF02786.17 EST45344.1 - 0.081 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain BBIP10 PF14777.6 EST45347.1 - 0.011 15.3 0.7 0.022 14.3 0.5 1.7 1 1 0 1 1 1 0 Cilia BBSome complex subunit 10 KIAA1430 PF13879.6 EST45347.1 - 7.3 7.4 12.7 2.3e+02 2.6 1.5 2.6 1 1 1 2 2 2 0 KIAA1430 homologue Ank_2 PF12796.7 EST45348.1 - 4.4e-06 27.2 2.0 0.019 15.5 0.0 3.7 2 1 2 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EST45348.1 - 7.1e-05 22.9 0.2 0.84 10.4 0.0 4.6 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 EST45348.1 - 0.0044 17.4 0.1 1.4 9.5 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 EST45348.1 - 0.013 16.1 0.2 19 5.9 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 EST45348.1 - 0.11 12.9 0.8 20 5.6 0.0 3.5 4 0 0 4 4 4 0 Ankyrin repeats (many copies) zf-C2HC_2 PF13913.6 EST45350.1 - 6.6e-10 38.6 9.5 1.8e-09 37.2 1.4 2.8 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-Di19 PF05605.12 EST45350.1 - 0.00026 21.2 11.0 0.0045 17.3 1.1 3.1 3 0 0 3 3 2 2 Drought induced 19 protein (Di19), zinc-binding DZR PF12773.7 EST45350.1 - 0.0043 17.0 12.0 0.0052 16.8 0.4 3.4 3 0 0 3 3 3 1 Double zinc ribbon Rad50_zn_hook PF04423.14 EST45350.1 - 0.0079 16.0 1.5 0.045 13.6 0.2 2.9 2 0 0 2 2 2 1 Rad50 zinc hook motif zinc_ribbon_2 PF13240.6 EST45350.1 - 0.015 15.0 4.0 0.015 15.0 4.0 3.0 3 0 0 3 3 3 0 zinc-ribbon domain FYVE PF01363.21 EST45350.1 - 0.036 14.2 7.8 1.2 9.3 0.1 3.5 3 0 0 3 3 3 0 FYVE zinc finger zf-C2H2_4 PF13894.6 EST45350.1 - 0.058 14.2 0.6 0.058 14.2 0.6 3.6 3 1 0 3 3 2 0 C2H2-type zinc finger SnAC PF14619.6 EST45350.1 - 0.12 13.0 0.1 0.12 13.0 0.1 2.4 2 1 0 2 2 2 0 Snf2-ATP coupling, chromatin remodelling complex DUF1360 PF07098.11 EST45350.1 - 0.14 12.2 0.1 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1360) zinc_ribbon_9 PF14369.6 EST45350.1 - 0.32 11.3 3.4 24 5.3 0.1 3.4 3 0 0 3 3 3 0 zinc-ribbon c-SKI_SMAD_bind PF08782.10 EST45350.1 - 0.99 9.7 7.7 1.7 8.9 0.1 3.4 3 0 0 3 3 3 0 c-SKI Smad4 binding domain HypA PF01155.19 EST45350.1 - 1.3 9.1 11.9 4 7.5 0.4 3.4 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 EST45350.1 - 1.9 8.5 13.1 8.2 6.5 1.2 3.5 3 0 0 3 3 3 0 zinc-ribbons PHF5 PF03660.14 EST45350.1 - 2 8.6 10.3 3 8.1 0.4 3.4 3 0 0 3 3 3 0 PHF5-like protein zf-H2C2_2 PF13465.6 EST45350.1 - 2.8 8.5 0.0 2.8 8.5 0.0 3.9 4 0 0 4 4 3 0 Zinc-finger double domain zf-ribbon_3 PF13248.6 EST45350.1 - 5.3 6.6 15.5 15 5.2 2.2 4.1 4 0 0 4 4 4 0 zinc-ribbon domain DENN PF02141.21 EST45350.1 - 6.7 6.6 9.3 0.35 10.8 3.3 1.8 2 0 0 2 2 2 0 DENN (AEX-3) domain Opy2 PF09463.10 EST45350.1 - 9.2 6.7 9.0 0.44 10.9 1.2 2.6 3 0 0 3 3 2 0 Opy2 protein DUF4187 PF13821.6 EST45350.1 - 9.9 6.0 7.9 5 7.0 0.8 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) Kelch_4 PF13418.6 EST45351.1 - 3.4e-10 39.8 9.1 0.13 12.3 0.0 4.5 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_3 PF13415.6 EST45351.1 - 6.8e-10 39.0 0.2 0.0015 18.8 0.0 3.8 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.6 EST45351.1 - 2.9e-05 24.2 6.3 0.81 10.1 0.1 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 EST45351.1 - 0.00014 21.4 7.0 0.38 10.4 0.2 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 EST45351.1 - 0.0003 20.7 2.5 0.021 14.8 0.0 3.9 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.15 EST45351.1 - 0.0052 16.7 9.0 0.041 13.9 0.2 3.9 4 1 0 4 4 4 1 Kelch motif DUF4407 PF14362.6 EST45352.1 - 0.085 12.2 0.1 0.091 12.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF5388 PF17363.2 EST45352.1 - 0.11 12.7 2.2 0.33 11.2 0.1 2.5 2 1 1 3 3 3 0 Family of unknown function (DUF5388) NPV_P10 PF05531.12 EST45352.1 - 1.5 9.4 4.2 2.7 8.5 0.3 2.5 2 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1729 PF08354.10 EST45354.1 - 0.067 12.1 0.7 0.077 11.9 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) HCMV_UL139 PF12507.8 EST45354.1 - 0.33 11.4 5.3 1.3 9.4 5.3 1.8 1 1 0 1 1 1 0 Human Cytomegalovirus UL139 protein TPR_7 PF13176.6 EST45355.1 - 0.00016 21.4 0.2 0.01 15.8 0.1 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EST45355.1 - 0.027 14.6 4.8 0.36 11.0 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 EST45355.1 - 0.038 14.2 2.4 4.7 7.7 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EST45355.1 - 1.2 9.7 5.7 3.2 8.3 0.6 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EST45355.1 - 1.5 8.8 4.8 3.2 7.7 0.3 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat PP2C PF00481.21 EST45356.1 - 4.3e-25 88.8 1.9 6.2e-25 88.3 0.3 1.8 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 EST45356.1 - 2.4e-09 37.2 0.0 5.1e-09 36.1 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C OST3_OST6 PF04756.13 EST45356.1 - 0.053 12.9 1.2 0.083 12.2 1.2 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family V-set_2 PF15910.5 EST45357.1 - 0.092 12.8 0.0 0.62 10.2 0.0 1.9 2 0 0 2 2 2 0 ICOS V-set domain VSP PF03302.13 EST45359.1 - 6.3e-18 64.8 382.9 0.00034 19.6 63.8 11.7 1 1 8 9 9 9 6 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST45359.1 - 0.0022 18.1 19.5 0.0022 18.1 19.5 15.8 1 1 13 14 14 14 3 Furin-like repeat, cysteine-rich MFS18 PF17352.2 EST45359.1 - 0.2 12.0 4.9 4.9 7.6 0.3 3.2 2 1 1 3 3 3 0 Male Flower Specific protein 18 VSP PF03302.13 EST45360.1 - 1e-12 47.7 488.8 0.0014 17.5 62.9 15.2 1 1 13 14 14 14 10 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST45360.1 - 0.0023 18.0 20.3 0.0023 18.0 20.3 18.5 1 1 14 16 16 16 3 Furin-like repeat, cysteine-rich MFS18 PF17352.2 EST45360.1 - 0.2 12.0 4.9 6.7 7.1 0.2 3.4 2 1 1 3 3 3 0 Male Flower Specific protein 18 VSP PF03302.13 EST45364.1 - 5.4e-08 32.1 349.4 0.096 11.5 44.6 11.9 2 1 6 8 8 8 6 Giardia variant-specific surface protein Podoplanin PF05808.11 EST45364.1 - 0.16 12.0 0.7 0.52 10.4 0.2 2.1 2 0 0 2 2 2 0 Podoplanin VSP PF03302.13 EST45367.1 - 9.1e-14 51.1 136.0 4.1e-05 22.6 23.2 6.1 1 1 5 6 6 6 5 Giardia variant-specific surface protein DUF4366 PF14283.6 EST45367.1 - 0.067 13.2 0.2 0.067 13.2 0.2 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) POTRA_TamA_1 PF17243.2 EST45368.1 - 0.19 11.9 0.4 1.1 9.4 0.0 2.4 3 0 0 3 3 3 0 POTRA domain TamA domain 1 M157 PF11624.8 EST45370.1 - 0.018 14.4 0.2 0.025 13.9 0.2 1.2 1 0 0 1 1 1 0 MHC class I-like protein M157 VSP PF03302.13 EST45372.1 - 3.3e-13 49.3 174.5 1.5e-05 24.0 21.5 7.2 1 1 6 7 7 7 5 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST45372.1 - 0.0021 18.2 162.5 0.013 15.6 21.9 8.3 1 1 7 8 8 8 5 Furin-like repeat, cysteine-rich PARM PF17061.5 EST45372.1 - 0.75 9.9 4.5 1.2 9.2 4.5 1.2 1 0 0 1 1 1 0 PARM VSP PF03302.13 EST45374.1 - 0.00065 18.7 134.7 0.0033 16.4 29.8 5.9 1 1 6 7 7 7 5 Giardia variant-specific surface protein DUF4366 PF14283.6 EST45374.1 - 0.071 13.2 0.4 0.16 12.0 0.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) DUF4748 PF15932.5 EST45374.1 - 0.24 11.2 1.7 0.42 10.4 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) zf-B_box PF00643.24 EST45376.1 - 4.3e-06 26.8 5.6 4.3e-06 26.8 5.6 4.7 4 1 0 4 4 4 2 B-box zinc finger DUF4637 PF15470.6 EST45376.1 - 0.0065 16.2 7.6 0.28 10.9 3.1 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4637) Ras PF00071.22 EST45377.1 - 1.1e-05 25.0 0.1 0.029 14.0 0.0 2.1 2 0 0 2 2 2 2 Ras family AAA_7 PF12775.7 EST45377.1 - 0.0019 17.7 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region Roc PF08477.13 EST45377.1 - 0.002 18.3 0.0 0.41 10.9 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 EST45377.1 - 0.014 15.6 0.0 0.021 15.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 EST45377.1 - 0.03 13.4 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 EST45377.1 - 0.032 14.0 0.0 0.074 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 EST45377.1 - 0.045 13.5 0.0 0.059 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EST45377.1 - 0.045 13.4 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 EST45377.1 - 0.058 13.8 0.0 0.092 13.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 EST45377.1 - 0.064 13.2 0.1 0.72 9.7 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 EST45377.1 - 0.073 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 EST45377.1 - 0.097 11.9 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Septin DUF3900 PF13039.6 EST45377.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3900) SRPRB PF09439.10 EST45377.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Hpr_kinase_C PF07475.12 EST45377.1 - 0.16 11.5 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_16 PF13191.6 EST45377.1 - 0.19 12.1 0.0 0.28 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Pkinase PF00069.25 EST45378.1 - 3.4e-45 154.5 8.7 7.8e-39 133.6 2.9 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EST45378.1 - 7.3e-33 113.9 1.7 4.4e-27 95.0 0.8 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EST45378.1 - 1.7e-05 23.8 0.2 3.8e-05 22.6 0.1 1.8 1 1 1 2 2 2 1 Fungal protein kinase ESAG1 PF03238.13 EST45378.1 - 0.0092 15.5 1.9 0.036 13.5 0.1 2.3 2 0 0 2 2 2 1 ESAG protein Pkinase PF00069.25 EST45379.1 - 1.4e-47 162.3 3.8 3.5e-41 141.3 2.6 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EST45379.1 - 2.1e-35 122.3 1.3 2e-29 102.6 0.7 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EST45379.1 - 0.00014 20.8 0.0 0.00025 19.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase NLE PF08154.12 EST45379.1 - 0.032 14.8 0.5 0.12 12.9 0.1 2.2 2 0 0 2 2 2 0 NLE (NUC135) domain Kdo PF06293.14 EST45379.1 - 0.079 12.3 0.2 0.15 11.4 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TCTP PF00838.17 EST45381.1 - 1.5e-22 80.7 6.8 4.7e-22 79.1 6.8 1.6 1 1 0 1 1 1 1 Translationally controlled tumour protein 2-oxogl_dehyd_N PF16078.5 EST45382.1 - 0.037 13.6 0.1 0.061 12.9 0.1 1.3 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase N-terminus VSP PF03302.13 EST45383.1 - 1e-13 50.9 303.3 0.00081 18.3 26.6 10.6 1 1 10 11 11 11 10 Giardia variant-specific surface protein CYYR1 PF10873.8 EST45384.1 - 0.0059 17.1 1.7 0.0059 17.1 1.7 1.5 1 1 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 MIT_C PF16565.5 EST45386.1 - 0.019 15.0 0.1 0.024 14.6 0.1 1.2 1 0 0 1 1 1 0 Phospholipase D-like domain at C-terminus of MIT PAE PF03283.13 EST45389.1 - 0.031 13.4 3.1 0.047 12.8 3.1 1.2 1 0 0 1 1 1 0 Pectinacetylesterase NAC PF01849.18 EST45389.1 - 0.12 12.3 0.0 0.45 10.5 0.0 1.9 2 0 0 2 2 2 0 NAC domain DUF4100 PF13352.6 EST45390.1 - 0.55 10.0 2.3 10 5.8 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF4100) Pox_A9 PF04835.12 EST45390.1 - 0.67 10.1 3.0 3.2 8.0 0.6 2.5 2 0 0 2 2 2 0 A9 protein conserved region CBFD_NFYB_HMF PF00808.23 EST45392.1 - 0.0064 16.8 0.1 0.012 15.9 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2552 PF10827.8 EST45393.1 - 0.013 15.7 0.0 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2552) VasL PF12486.8 EST45394.1 - 0.019 14.9 0.2 0.023 14.6 0.2 1.2 1 0 0 1 1 1 0 Type VI secretion system, EvfB, or VasL DUF971 PF06155.12 EST45394.1 - 0.073 13.7 0.3 0.2 12.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF971) RTX PF02382.15 EST45394.1 - 0.074 12.7 0.4 0.098 12.3 0.4 1.1 1 0 0 1 1 1 0 N-terminal domain in RTX protein Nudix_N PF12535.8 EST45394.1 - 0.1 12.2 0.2 0.19 11.3 0.2 1.4 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal DUF1811 PF08838.10 EST45394.1 - 0.11 12.8 1.1 0.15 12.3 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1811) HJURP_C PF12347.8 EST45394.1 - 0.13 12.3 1.1 0.31 11.1 0.3 1.9 1 1 1 2 2 2 0 Holliday junction regulator protein family C-terminal repeat Putative_PNPOx PF01243.20 EST45395.1 - 0.00023 21.3 0.0 0.00033 20.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF3208 PF11482.8 EST45396.1 - 0.26 11.6 2.8 0.32 11.3 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3208) DUF4172 PF13776.6 EST45396.1 - 0.38 11.1 4.5 4.2 7.8 0.3 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4172) Viral_P18 PF04521.13 EST45396.1 - 5.5 6.8 13.6 0.38 10.5 0.3 3.7 3 1 0 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein SHIPPO-rpt PF07004.12 EST45397.1 - 4.4e-14 52.6 31.2 0.0005 20.8 1.7 6.5 6 0 0 6 6 6 6 Sperm-tail PG-rich repeat SHIPPO-rpt PF07004.12 EST45398.1 - 0.00011 22.9 17.0 0.00055 20.7 0.2 3.4 3 1 0 3 3 3 2 Sperm-tail PG-rich repeat ArAE_2_N PF10337.9 EST45399.1 - 0.084 11.9 0.0 0.11 11.5 0.0 1.0 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Metallophos PF00149.28 EST45400.1 - 7.5e-16 59.2 1.8 1.2e-15 58.5 0.5 1.9 1 1 0 2 2 2 1 Calcineurin-like phosphoesterase Transglut_core PF01841.19 EST45401.1 - 0.016 15.7 0.0 0.042 14.3 0.0 1.7 1 0 0 1 1 1 0 Transglutaminase-like superfamily TcpS PF17456.2 EST45402.1 - 0.017 15.2 0.9 0.02 15.0 0.9 1.3 1 0 0 1 1 1 0 Toxin-coregulated pilus protein S VSP PF03302.13 EST45403.1 - 1.1e-07 31.1 244.1 0.0026 16.7 37.7 8.0 1 1 7 8 8 8 7 Giardia variant-specific surface protein DUF4337 PF14235.6 EST45404.1 - 0.011 15.9 1.8 0.024 14.7 1.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Utp12 PF04003.12 EST45404.1 - 0.21 11.9 1.6 23 5.4 0.1 2.5 2 0 0 2 2 2 0 Dip2/Utp12 Family Pkr1 PF08636.10 EST45408.1 - 0.53 10.5 5.1 9.2 6.5 0.1 2.1 2 0 0 2 2 2 0 ER protein Pkr1 FliD_N PF02465.18 EST45409.1 - 2 9.2 15.4 0.64 10.7 8.4 3.4 2 2 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Exonuc_VII_L PF02601.15 EST45409.1 - 8.6 5.8 33.7 6.8 6.2 10.0 2.3 1 1 1 2 2 2 0 Exonuclease VII, large subunit Myb_DNA-binding PF00249.31 EST45410.1 - 4.4e-08 33.2 1.7 5.8e-08 32.8 1.7 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EST45410.1 - 1.1e-05 25.5 0.7 1.8e-05 24.8 0.7 1.2 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_6 PF13921.6 EST45410.1 - 1.2e-05 25.5 0.5 1.4e-05 25.3 0.5 1.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Peptidase_C27 PF05407.12 EST45413.1 - 1.9 8.5 7.5 4 7.5 1.6 2.7 2 1 1 3 3 3 0 Rubella virus endopeptidase Kelch_1 PF01344.25 EST45416.1 - 3.7e-20 71.2 0.7 2.9e-10 39.5 0.0 4.7 6 0 0 6 6 6 3 Kelch motif Kelch_3 PF13415.6 EST45416.1 - 1.6e-17 63.3 0.0 8.2e-08 32.4 0.0 4.5 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.6 EST45416.1 - 3.9e-17 61.9 1.9 1.8e-06 28.0 0.0 5.8 5 1 1 6 6 6 3 Kelch motif Kelch_4 PF13418.6 EST45416.1 - 2.2e-14 53.2 0.7 2.5e-07 30.6 0.0 3.9 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 EST45416.1 - 7.5e-14 51.3 1.2 2.1e-08 34.0 0.0 4.8 5 0 0 5 5 5 1 Kelch motif Kelch_2 PF07646.15 EST45416.1 - 8.3e-10 38.3 0.3 7.2e-05 22.6 0.0 5.0 5 0 0 5 5 5 2 Kelch motif FYVE_2 PF02318.16 EST45417.1 - 0.09 13.0 1.2 0.12 12.6 1.2 1.2 1 0 0 1 1 1 0 FYVE-type zinc finger Myb_DNA-binding PF00249.31 EST45419.1 - 9.2e-12 45.0 0.1 1.4e-11 44.3 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST45419.1 - 5.7e-06 26.5 0.4 1.1e-05 25.5 0.1 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Staphostatin_A PF09022.10 EST45419.1 - 0.048 13.6 2.0 5.1 7.1 0.1 2.9 2 1 1 3 3 3 0 Staphostatin A Kinesin PF00225.23 EST45420.1 - 2.6e-114 381.6 0.9 2.6e-114 381.6 0.9 2.2 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EST45420.1 - 1.1e-29 103.3 0.1 1.1e-29 103.3 0.1 2.6 2 1 0 2 2 2 1 Microtubule binding SCVP PF17619.2 EST45420.1 - 0.32 11.9 3.7 0.95 10.4 0.2 2.9 2 0 0 2 2 2 0 Secreted clade V proteins Sugar_tr PF00083.24 EST45421.1 - 6.9e-35 120.8 35.2 1.6e-34 119.6 35.2 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EST45421.1 - 1.2e-10 40.9 26.5 1.2e-10 40.9 26.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Imm43 PF15570.6 EST45421.1 - 0.063 13.3 0.1 0.2 11.7 0.0 1.8 2 0 0 2 2 2 0 Immunity protein 43 DUF2530 PF10745.9 EST45421.1 - 0.73 10.1 4.6 0.5 10.6 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) KIAA1430 PF13879.6 EST45423.1 - 0.00026 21.7 1.0 0.00026 21.7 1.0 2.8 3 0 0 3 3 3 1 KIAA1430 homologue GCHY-1 PF02649.14 EST45423.1 - 0.0056 16.2 0.3 0.0088 15.6 0.3 1.3 1 0 0 1 1 1 1 Type I GTP cyclohydrolase folE2 Ribosomal_S8e PF01201.22 EST45424.1 - 1.2e-38 132.4 4.0 2.3e-38 131.4 4.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S8e Serpin PF00079.20 EST45426.1 - 4.2e-57 194.1 1.7 1.7e-48 165.8 0.2 2.0 1 1 1 2 2 2 2 Serpin (serine protease inhibitor) Pkinase PF00069.25 EST45427.1 - 1.3e-60 205.0 0.0 2e-60 204.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST45427.1 - 7.1e-41 140.2 0.0 9.7e-41 139.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EST45427.1 - 0.00063 19.2 1.7 0.17 11.2 0.2 2.6 2 1 1 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 EST45427.1 - 0.0013 17.6 0.0 0.0027 16.6 0.0 1.5 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EST45427.1 - 0.0019 17.6 0.2 0.0032 16.9 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-C3HC4 PF00097.25 EST45427.1 - 0.087 12.7 0.2 0.17 11.8 0.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_L20 PF00453.18 EST45427.1 - 0.089 12.9 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein L20 APH PF01636.23 EST45427.1 - 0.1 12.5 0.0 2.8 7.8 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family zf-rbx1 PF12678.7 EST45427.1 - 0.16 12.2 0.0 0.33 11.3 0.0 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain DUF963 PF06131.11 EST45428.1 - 0.082 12.3 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) AAA_6 PF12774.7 EST45429.1 - 7.5e-144 478.7 0.0 6.4e-141 469.0 0.0 3.2 2 0 0 2 2 2 2 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EST45429.1 - 1.1e-105 354.0 16.4 1.1e-105 354.0 16.4 7.0 8 0 0 8 8 7 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 EST45429.1 - 6.3e-85 285.9 23.1 6.3e-85 285.9 23.1 5.6 5 0 0 5 5 4 1 Dynein heavy chain, N-terminal region 1 AAA_8 PF12780.7 EST45429.1 - 9.1e-85 284.1 0.0 3.3e-84 282.3 0.0 2.1 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 EST45429.1 - 4.2e-81 272.5 0.1 4.2e-81 272.5 0.1 2.6 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 EST45429.1 - 5.1e-74 248.1 3.7 5.1e-74 248.1 3.7 5.2 5 1 0 5 5 5 1 ATP-binding dynein motor region MT PF12777.7 EST45429.1 - 1.4e-51 175.5 15.0 1.4e-51 175.5 15.0 2.6 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 EST45429.1 - 1e-44 152.2 0.4 3.5e-44 150.5 0.4 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_7 PF12775.7 EST45429.1 - 8.9e-42 142.6 2.4 3.2e-28 98.5 0.0 7.1 6 1 1 7 7 7 4 P-loop containing dynein motor region Dynein_heavy PF03028.15 EST45429.1 - 2.4e-41 140.5 0.0 5.2e-37 126.6 0.0 3.9 3 0 0 3 3 3 2 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 EST45429.1 - 5.5e-20 71.8 0.0 4e-19 69.0 0.0 2.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 EST45429.1 - 3.3e-17 62.5 0.3 3.7e-16 59.2 0.0 3.1 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 EST45429.1 - 2.5e-10 40.5 8.1 0.15 12.1 0.0 9.0 9 1 0 9 9 7 3 AAA domain (dynein-related subfamily) AAA PF00004.29 EST45429.1 - 1.4e-09 38.5 0.2 0.041 14.3 0.0 6.1 6 0 0 6 6 6 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EST45429.1 - 0.00013 22.3 0.3 4.4 7.6 0.0 5.6 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 EST45429.1 - 0.00022 21.7 7.9 0.94 9.8 0.0 7.4 7 0 0 7 7 7 1 AAA ATPase domain Mg_chelatase PF01078.21 EST45429.1 - 0.018 14.4 0.2 23 4.3 0.0 3.8 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EST45429.1 - 0.022 15.3 0.1 37 4.9 0.0 4.9 4 0 0 4 4 3 0 AAA domain AAA_29 PF13555.6 EST45429.1 - 5.5 6.8 5.1 13 5.6 0.1 3.2 3 0 0 3 3 3 0 P-loop containing region of AAA domain BLOC1_2 PF10046.9 EST45430.1 - 0.0045 17.3 5.9 0.0045 17.3 5.9 2.2 1 1 2 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-F_leu_zip PF10473.9 EST45430.1 - 0.0074 16.3 4.3 0.0074 16.3 4.3 2.0 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.6 EST45430.1 - 0.012 15.0 7.5 0.054 12.8 7.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Prominin PF05478.11 EST45430.1 - 0.014 13.4 6.3 0.016 13.2 6.3 1.1 1 0 0 1 1 1 0 Prominin DUF1640 PF07798.11 EST45430.1 - 0.019 15.0 6.3 0.028 14.5 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Lectin_N PF03954.14 EST45430.1 - 0.026 14.3 5.6 0.03 14.1 4.2 1.7 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain RRF_GI PF12614.8 EST45430.1 - 0.036 14.2 4.9 0.68 10.1 1.0 2.1 1 1 1 2 2 2 0 Ribosome recycling factor DUF3450 PF11932.8 EST45430.1 - 0.049 12.9 8.3 0.062 12.6 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Fib_alpha PF08702.10 EST45430.1 - 0.082 13.1 10.5 0.21 11.7 9.9 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Fungal_TACC PF12709.7 EST45430.1 - 0.098 13.1 1.2 0.098 13.1 1.2 2.5 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins GIT_CC PF16559.5 EST45430.1 - 0.24 11.3 8.4 3.1 7.7 4.7 2.6 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor FlxA PF14282.6 EST45430.1 - 0.26 11.3 15.5 1.1 9.3 15.5 1.9 1 1 1 2 2 2 0 FlxA-like protein ADIP PF11559.8 EST45430.1 - 0.27 11.3 12.1 0.24 11.5 6.1 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4164 PF13747.6 EST45430.1 - 0.27 11.5 5.2 0.24 11.7 1.2 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4164) Uso1_p115_C PF04871.13 EST45430.1 - 0.29 11.5 5.9 1.9 8.9 5.9 1.9 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF5082 PF16888.5 EST45430.1 - 0.33 11.2 10.0 2.1 8.6 10.0 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) DUF148 PF02520.17 EST45430.1 - 0.36 11.0 10.9 0.42 10.7 8.9 1.9 1 1 1 2 2 2 0 Domain of unknown function DUF148 Syntaxin_2 PF14523.6 EST45430.1 - 0.36 11.2 10.8 0.86 10.0 10.8 1.7 1 1 0 1 1 1 0 Syntaxin-like protein DUF4988 PF16378.5 EST45430.1 - 0.39 10.4 4.9 1 9.0 4.7 1.7 1 1 0 1 1 1 0 Domain of unknown function SlyX PF04102.12 EST45430.1 - 0.56 10.9 10.9 1 10.0 1.2 2.7 1 1 1 2 2 2 0 SlyX FAD-SLDH PF12318.8 EST45430.1 - 0.57 10.2 3.1 0.65 10.1 2.2 1.5 1 1 1 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase ACCA PF03255.14 EST45430.1 - 0.61 10.0 6.4 1 9.2 1.0 2.1 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit LPP PF04728.13 EST45430.1 - 0.68 10.4 7.6 5.2 7.5 0.2 2.7 2 2 1 3 3 3 0 Lipoprotein leucine-zipper KxDL PF10241.9 EST45430.1 - 0.77 10.1 9.2 1.1 9.6 1.3 2.9 1 1 2 3 3 3 0 Uncharacterized conserved protein TMF_DNA_bd PF12329.8 EST45430.1 - 0.79 9.8 11.3 0.6 10.1 2.6 3.1 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding ABC_tran_CTD PF16326.5 EST45430.1 - 0.8 10.0 7.5 0.44 10.8 1.4 2.4 1 1 2 3 3 3 0 ABC transporter C-terminal domain OmpH PF03938.14 EST45430.1 - 0.9 9.9 11.2 2.5 8.4 11.2 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) TMPIT PF07851.13 EST45430.1 - 0.95 8.6 5.8 1 8.5 5.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein ZapB PF06005.12 EST45430.1 - 1.4 9.4 12.3 3.9 8.0 5.1 2.6 1 1 1 2 2 2 0 Cell division protein ZapB DUF1664 PF07889.12 EST45430.1 - 1.6 8.8 6.3 3.7 7.6 5.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) bZIP_2 PF07716.15 EST45430.1 - 2.8 8.1 10.7 0.51 10.5 0.6 3.1 2 1 1 3 3 3 0 Basic region leucine zipper CLZ PF16526.5 EST45430.1 - 3.3 8.1 7.8 1.7 9.1 2.9 2.3 1 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TolA_bind_tri PF16331.5 EST45430.1 - 5.5 7.1 12.3 2 8.5 7.1 2.5 1 1 0 2 2 2 0 TolA binding protein trimerisation DASH_Hsk3 PF08227.11 EST45430.1 - 6.7 7.2 13.4 4.8 7.6 7.0 2.9 2 1 1 3 3 3 0 DASH complex subunit Hsk3 like TB2_DP1_HVA22 PF03134.19 EST45431.1 - 5.7e-12 45.4 1.7 9.5e-12 44.7 1.7 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family KleE PF17394.2 EST45431.1 - 0.013 15.7 1.3 0.021 15.0 1.3 1.4 1 0 0 1 1 1 0 Uncharacterized KleE stable inheritance protein DUF981 PF06168.11 EST45431.1 - 0.016 15.2 3.0 0.02 14.8 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF981) FliD_N PF02465.18 EST45433.1 - 2 9.2 15.4 0.64 10.7 8.4 3.4 2 2 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Exonuc_VII_L PF02601.15 EST45433.1 - 8.6 5.8 33.7 6.8 6.2 10.0 2.3 1 1 1 2 2 2 0 Exonuclease VII, large subunit Cation_ATPase_C PF00689.21 EST45438.1 - 2.7e-38 131.5 9.6 2.7e-38 131.5 9.6 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EST45438.1 - 1.4e-37 128.9 1.4 1.4e-37 128.9 1.4 3.4 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 EST45438.1 - 1.9e-16 61.0 0.9 6.3e-16 59.3 0.9 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EST45438.1 - 2.4e-15 56.0 0.0 7.8e-15 54.3 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EST45438.1 - 1.6e-11 44.1 0.3 4.1e-11 42.8 0.3 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EST45438.1 - 1.7e-05 24.7 0.1 8.8e-05 22.4 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase VirB3 PF05101.13 EST45438.1 - 4.8 7.5 9.5 2.9 8.2 1.3 3.3 3 0 0 3 3 3 0 Type IV secretory pathway, VirB3-like protein SHIPPO-rpt PF07004.12 EST45439.1 - 0.02 15.8 2.0 2.7 9.1 0.3 3.1 3 0 0 3 3 3 0 Sperm-tail PG-rich repeat EF-hand_7 PF13499.6 EST45440.1 - 0.00039 20.8 0.1 0.0023 18.3 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EST45440.1 - 0.0012 18.6 1.3 0.0018 18.0 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 EST45440.1 - 0.0068 15.9 0.0 0.028 14.0 0.0 2.0 1 0 0 1 1 1 1 EF hand Methyltransf_32 PF13679.6 EST45441.1 - 1.8e-10 41.1 1.2 1.6e-07 31.4 1.2 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EST45441.1 - 3.5e-06 26.9 0.0 5.7e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EST45441.1 - 0.00013 22.6 0.3 0.0003 21.4 0.3 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EST45441.1 - 0.00035 20.4 0.1 0.00065 19.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 EST45441.1 - 0.001 18.7 0.1 0.0017 18.0 0.1 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_11 PF08241.12 EST45441.1 - 0.0028 18.3 0.1 0.0061 17.2 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EST45441.1 - 0.0031 16.9 1.5 0.0047 16.4 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 EST45441.1 - 0.12 13.1 0.1 0.25 12.1 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain LRR_9 PF14580.6 EST45442.1 - 6.7e-19 68.1 0.8 3.6e-15 55.9 0.2 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 EST45442.1 - 1e-16 60.8 18.0 2.1e-06 28.0 0.6 3.6 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EST45442.1 - 8.3e-11 41.5 21.0 1.1e-06 28.3 4.1 3.8 2 1 2 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 EST45442.1 - 0.089 12.9 10.0 0.84 9.8 0.4 4.8 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 EST45442.1 - 0.54 11.0 15.0 15 6.6 0.4 5.1 6 0 0 6 6 6 0 Leucine Rich Repeat DUF2856 PF11043.8 EST45444.1 - 0.022 14.9 0.1 0.03 14.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2856) DEAD PF00270.29 EST45445.1 - 1.1e-26 93.6 0.6 8.9e-26 90.7 0.0 2.5 2 1 1 3 3 3 1 DEAD/DEAH box helicase DUF4217 PF13959.6 EST45445.1 - 6.3e-19 68.0 0.0 2e-18 66.4 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 EST45445.1 - 1.3e-18 67.4 3.9 2.5e-18 66.5 0.2 2.8 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EST45445.1 - 3e-09 37.1 5.0 5e-08 33.1 0.0 3.5 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EST45445.1 - 0.00021 21.6 4.0 1.7 8.9 0.1 4.1 3 1 0 3 3 3 2 AAA domain AAA_7 PF12775.7 EST45445.1 - 0.028 13.9 0.1 1.1 8.8 0.0 2.8 3 0 0 3 3 3 0 P-loop containing dynein motor region FMN_bind_2 PF04299.12 EST45445.1 - 0.16 11.7 0.4 0.76 9.5 0.0 2.2 2 0 0 2 2 2 0 Putative FMN-binding domain Cyt-b5 PF00173.28 EST45447.1 - 1.6e-05 24.9 0.0 2.6e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF1910 PF08928.10 EST45447.1 - 0.2 11.6 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) Myb_DNA-binding PF00249.31 EST45449.1 - 1.8e-07 31.3 0.0 3.3e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST45449.1 - 5.4e-06 26.6 0.0 7.4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain VSP PF03302.13 EST45451.1 - 0.0051 15.7 16.2 0.0051 15.7 16.2 4.1 1 1 3 4 4 4 2 Giardia variant-specific surface protein FYVE_2 PF02318.16 EST45451.1 - 0.0056 16.9 5.0 0.0056 16.9 5.0 4.5 2 1 3 5 5 5 1 FYVE-type zinc finger WD40 PF00400.32 EST45455.1 - 5.7e-07 30.1 0.8 0.038 14.9 0.0 4.3 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EST45455.1 - 0.0012 19.1 0.0 0.079 13.3 0.0 3.2 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EST45455.1 - 0.0049 15.9 0.5 0.014 14.4 0.5 1.7 1 1 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 EST45455.1 - 0.016 14.3 1.4 1.8 7.5 0.1 2.6 1 1 1 2 2 2 0 Coatomer WD associated region T3SSipB PF16535.5 EST45456.1 - 0.019 15.4 0.1 0.022 15.3 0.1 1.1 1 0 0 1 1 1 0 Type III cell invasion protein SipB RCC1_2 PF13540.6 EST45460.1 - 0.0094 15.7 0.6 0.59 10.0 0.0 3.9 4 1 0 4 4 4 1 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 EST45460.1 - 0.013 16.1 5.4 6.1 7.5 0.1 4.6 5 0 0 5 5 5 0 Regulator of chromosome condensation (RCC1) repeat LSM PF01423.22 EST45461.1 - 5.7e-07 29.1 0.0 6.8e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EST45461.1 - 0.00026 21.1 0.0 0.00029 20.9 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF150_C PF17384.2 EST45461.1 - 0.13 12.5 0.0 0.13 12.5 0.0 1.2 1 1 0 1 1 1 0 RimP C-terminal SH3 domain SLC35F PF06027.12 EST45462.1 - 0.019 14.5 10.6 0.035 13.6 6.9 2.2 1 1 1 2 2 2 0 Solute carrier family 35 Peptidase_C1 PF00112.23 EST45463.1 - 3.1e-44 151.6 0.9 3.6e-44 151.4 0.9 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EST45463.1 - 0.025 13.4 0.7 0.035 12.9 0.7 1.1 1 0 0 1 1 1 0 Peptidase C1-like family Thioredoxin PF00085.20 EST45464.1 - 3.5e-14 52.7 0.0 3.6e-14 52.6 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 EST45464.1 - 0.052 13.7 0.1 0.074 13.2 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_2 PF13098.6 EST45464.1 - 0.13 12.7 0.1 1.2 9.6 0.1 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain eRF1_2 PF03464.15 EST45466.1 - 4.9e-37 127.2 0.0 8.7e-37 126.4 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EST45466.1 - 4.6e-31 107.6 0.0 1.4e-30 106.1 0.0 1.8 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 EST45466.1 - 0.00015 21.7 0.0 0.00031 20.7 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 EST45466.1 - 0.0028 17.9 0.0 0.0045 17.3 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor ACP PF06857.11 EST45467.1 - 0.12 12.6 0.1 0.15 12.3 0.1 1.1 1 0 0 1 1 1 0 Malonate decarboxylase delta subunit (MdcD) E1-E2_ATPase PF00122.20 EST45467.1 - 0.13 11.8 0.3 0.13 11.7 0.3 1.0 1 0 0 1 1 1 0 E1-E2 ATPase DUF3377 PF11857.8 EST45467.1 - 0.15 12.0 0.5 0.24 11.3 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Spem1 PF15670.5 EST45467.1 - 0.2 11.2 0.5 0.25 10.9 0.5 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 EF-hand_1 PF00036.32 EST45470.1 - 0.00025 20.4 0.0 0.00096 18.5 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EST45470.1 - 0.00083 19.1 0.2 0.0098 15.8 0.1 2.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 EST45470.1 - 0.0016 17.9 0.2 0.0043 16.5 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EST45470.1 - 0.004 17.6 0.3 0.077 13.5 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 EST45470.1 - 0.019 14.8 0.2 0.52 10.2 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain pair Nucleoside_tran PF01733.18 EST45472.1 - 0.00033 20.1 5.3 0.00033 20.1 5.3 2.1 1 1 0 2 2 2 1 Nucleoside transporter DUF5083 PF16890.5 EST45472.1 - 0.034 13.9 1.2 0.034 13.9 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5083) Oxidored_q5_N PF01059.17 EST45472.1 - 5.8 7.0 19.3 2.5 8.2 14.5 2.1 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus Spec3 PF15795.5 EST45474.1 - 0.00021 21.7 14.2 0.0091 16.5 7.5 2.0 1 1 1 2 2 2 2 Ectodermal ciliogenesis protein Lysis_col PF02402.16 EST45474.1 - 0.098 12.3 0.4 0.098 12.3 0.4 1.9 2 1 0 2 2 2 0 Lysis protein TrbI_Ftype PF09677.10 EST45475.1 - 0.11 12.8 0.5 0.15 12.3 0.4 1.3 1 1 0 1 1 1 0 Type-F conjugative transfer system protein (TrbI_Ftype) IncFII_repA PF02387.15 EST45476.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 IncFII RepA protein family Acetyltransf_11 PF13720.6 EST45477.1 - 0.0074 16.7 0.0 0.17 12.4 0.0 2.1 1 1 1 2 2 2 1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Phage_Coat_A PF05357.13 EST45477.1 - 0.07 12.9 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 Phage Coat Protein A NETI PF14044.6 EST45479.1 - 0.04 13.7 0.5 0.092 12.5 0.1 1.8 2 0 0 2 2 2 0 NETI protein Acetyltransf_1 PF00583.25 EST45480.1 - 2.2e-15 56.9 0.0 2.6e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EST45480.1 - 3.7e-09 36.6 0.1 4.8e-09 36.2 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EST45480.1 - 5.7e-07 29.9 0.0 7.4e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EST45480.1 - 7.3e-05 22.8 0.1 0.00011 22.3 0.1 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 EST45480.1 - 0.0015 18.4 0.0 0.0051 16.8 0.0 1.8 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_3 PF13302.7 EST45480.1 - 0.0026 18.4 0.0 0.0035 18.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EST45480.1 - 0.036 14.1 0.0 0.045 13.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Spc42p PF11544.8 EST45481.1 - 0.029 14.4 0.2 0.044 13.8 0.2 1.2 1 0 0 1 1 1 0 Spindle pole body component Spc42p Arm_3 PF16186.5 EST45481.1 - 0.12 11.9 1.4 0.23 11.0 0.1 2.0 2 0 0 2 2 2 0 Atypical Arm repeat PH_11 PF15413.6 EST45481.1 - 0.55 10.7 2.9 0.74 10.3 2.6 1.3 1 1 0 1 1 1 0 Pleckstrin homology domain Rsm22 PF09243.10 EST45483.1 - 0.27 10.5 3.0 0.3 10.3 2.6 1.3 1 1 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Acetyltransf_1 PF00583.25 EST45484.1 - 2.2e-15 56.9 0.0 2.6e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EST45484.1 - 3.7e-09 36.6 0.1 4.8e-09 36.2 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EST45484.1 - 5.7e-07 29.9 0.0 7.4e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EST45484.1 - 7.3e-05 22.8 0.1 0.00011 22.3 0.1 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 EST45484.1 - 0.0015 18.4 0.0 0.0051 16.8 0.0 1.8 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_3 PF13302.7 EST45484.1 - 0.0026 18.4 0.0 0.0035 18.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EST45484.1 - 0.036 14.1 0.0 0.045 13.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain VSP PF03302.13 EST45485.1 - 1e-05 24.6 19.6 1e-05 24.6 19.6 2.8 1 1 1 2 2 2 1 Giardia variant-specific surface protein Sugar_tr PF00083.24 EST45486.1 - 6.9e-59 199.9 34.3 3.6e-39 134.9 11.9 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EST45486.1 - 5.9e-18 64.9 35.7 8.8e-15 54.5 26.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EST45486.1 - 0.00099 18.5 13.2 0.00099 18.5 13.2 1.7 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 EST45486.1 - 0.12 10.7 12.6 0.04 12.4 9.1 1.8 1 1 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Nucleoside_tran PF01733.18 EST45487.1 - 7.6e-22 78.1 15.4 7.6e-22 78.1 15.4 2.4 1 1 1 2 2 2 1 Nucleoside transporter Heliorhodopsin PF18761.1 EST45491.1 - 0.01 15.1 0.8 0.013 14.8 0.5 1.3 1 1 0 1 1 1 0 Heliorhodopsin THDPS_N PF14790.6 EST45491.1 - 1.9 8.3 7.9 3.5 7.4 0.6 2.1 2 0 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal ATG16 PF08614.11 EST45492.1 - 0.0039 17.4 37.3 0.0056 16.9 16.9 6.0 2 1 2 5 5 5 3 Autophagy protein 16 (ATG16) PSRP-3_Ycf65 PF04839.13 EST45494.1 - 0.096 12.9 0.1 0.21 11.8 0.1 1.6 1 0 0 1 1 1 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) Nucleoside_tran PF01733.18 EST45495.1 - 3e-22 79.4 15.9 3e-22 79.4 15.9 2.4 1 1 1 2 2 2 1 Nucleoside transporter Kelch_4 PF13418.6 EST45497.1 - 2.4e-34 117.1 1.1 5.1e-12 45.6 0.3 4.6 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_3 PF13415.6 EST45497.1 - 1.6e-22 79.3 0.8 5e-08 33.0 0.1 4.5 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.6 EST45497.1 - 1.3e-17 63.3 2.9 2.5e-08 33.9 0.1 4.8 3 1 2 5 5 5 3 Kelch motif Kelch_1 PF01344.25 EST45497.1 - 5.6e-14 51.5 0.8 1.4e-05 24.5 0.1 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 EST45497.1 - 2e-13 50.0 1.5 3.3e-05 23.8 0.0 5.5 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 EST45497.1 - 1.9e-09 37.1 2.8 0.0027 17.6 0.0 4.6 5 0 0 5 5 5 3 Kelch motif Pro_sub2 PF18513.1 EST45497.1 - 0.061 13.5 0.7 0.9 9.8 0.4 2.5 2 0 0 2 2 2 0 Prodomain subtilisin 2 Homeodomain PF00046.29 EST45497.1 - 0.066 13.1 0.3 0.066 13.1 0.3 2.2 2 0 0 2 2 2 0 Homeodomain Sugar_tr PF00083.24 EST45498.1 - 2.6e-58 198.0 36.7 9.3e-39 133.5 12.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EST45498.1 - 8.7e-15 54.5 41.8 1.5e-11 43.9 31.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SelK_SelG PF10961.8 EST45498.1 - 2.8 8.6 4.2 0.98 10.1 0.3 2.3 2 0 0 2 2 2 0 Selenoprotein SelK_SelG Y_phosphatase PF00102.27 EST45499.1 - 1.2e-28 100.3 0.0 1.5e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 EST45499.1 - 6.5e-06 26.0 0.0 1.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EST45499.1 - 0.00034 20.7 0.1 0.00098 19.2 0.0 1.5 1 1 0 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 EST45499.1 - 0.00036 20.7 0.1 0.0011 19.1 0.0 1.8 1 1 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 EST45499.1 - 0.0076 15.8 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF2175 PF09943.9 EST45500.1 - 0.18 12.1 2.4 0.27 11.5 1.2 1.9 1 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Myb_DNA-binding PF00249.31 EST45501.1 - 1.9e-08 34.3 0.0 0.00052 20.1 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST45501.1 - 9.5e-07 29.0 0.1 0.04 14.2 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EST45501.1 - 0.0034 17.5 0.0 2.9 8.2 0.0 2.1 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 Ribosomal_L31 PF01197.18 EST45501.1 - 0.11 12.7 0.1 0.21 11.8 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L31 Herpes_TK_C PF08465.10 EST45501.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Thymidine kinase from Herpesvirus C-terminal Proteasome PF00227.26 EST45502.1 - 1.7e-17 63.6 0.0 2.4e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EST45502.1 - 3.9e-12 45.6 0.1 7.2e-12 44.8 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Phage-Gp8 PF09215.10 EST45504.1 - 0.051 12.6 0.0 0.058 12.5 0.0 1.0 1 0 0 1 1 1 0 Bacteriophage T4, Gp8 Ribosomal_60s PF00428.19 EST45505.1 - 1.2e-10 41.8 14.5 1.4e-10 41.6 14.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein SAPIS-gp6 PF16722.5 EST45505.1 - 0.16 12.4 0.1 0.16 12.4 0.1 1.6 2 0 0 2 2 2 0 Pathogenicity island protein gp6 in Staphylococcus Pox_VLTF3 PF04947.14 EST45505.1 - 0.18 11.6 0.0 0.2 11.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like DapB_C PF05173.14 EST45505.1 - 0.18 11.8 1.5 0.24 11.5 1.4 1.3 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, C-terminus Myb_DNA-binding PF00249.31 EST45506.1 - 6.4e-05 23.1 0.0 9.2e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST45506.1 - 0.00081 19.6 0.1 0.0011 19.2 0.1 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST45506.1 - 0.035 14.0 0.1 0.038 13.9 0.1 1.1 1 0 0 1 1 1 0 Myb DNA-binding like CLN3 PF02487.17 EST45507.1 - 3.7e-07 29.5 0.1 4.1e-07 29.4 0.1 1.0 1 0 0 1 1 1 1 CLN3 protein ATP-synt_C PF00137.21 EST45511.1 - 4.1e-29 100.7 38.9 1.2e-17 64.0 17.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C CLP_protease PF00574.23 EST45511.1 - 0.087 12.7 2.1 0.14 12.0 2.1 1.3 1 0 0 1 1 1 0 Clp protease Bax1-I PF01027.20 EST45511.1 - 2.2 8.1 16.0 12 5.6 16.1 2.0 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 AvrB_AvrC PF05394.11 EST45512.1 - 0.19 10.9 0.0 0.3 10.2 0.0 1.2 1 0 0 1 1 1 0 Avirulence protein Ig_J_chain PF15097.6 EST45513.1 - 0.059 13.2 0.7 0.12 12.3 0.2 1.7 2 0 0 2 2 2 0 Immunoglobulin J chain Ig_J_chain PF15097.6 EST45516.1 - 0.071 13.0 0.8 0.14 12.1 0.3 1.7 2 0 0 2 2 2 0 Immunoglobulin J chain Rhabdo_glycop PF00974.18 EST45517.1 - 0.026 13.0 0.0 0.03 12.8 0.0 1.0 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein GRIM-19 PF06212.12 EST45517.1 - 0.11 12.4 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 GRIM-19 protein LCAT PF02450.15 EST45517.1 - 0.16 11.1 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Stevor PF17410.2 EST45518.1 - 0.065 12.8 0.1 0.065 12.8 0.1 2.4 2 1 0 2 2 2 0 Subtelomeric Variable Open Reading frame SKG6 PF08693.10 EST45518.1 - 0.42 10.1 6.3 0.71 9.3 6.3 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syndecan PF01034.20 EST45518.1 - 1.7 8.6 3.4 3.1 7.8 3.4 1.3 1 0 0 1 1 1 0 Syndecan domain Pkinase PF00069.25 EST45519.1 - 1.5e-71 240.8 0.0 1.9e-71 240.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST45519.1 - 2.6e-37 128.5 0.0 3.5e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EST45519.1 - 0.0066 15.8 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EST45519.1 - 0.054 12.8 0.1 0.42 9.9 0.0 2.4 2 1 0 2 2 2 0 Kinase-like Nucleoside_tran PF01733.18 EST45520.1 - 7.5e-10 38.7 19.3 6.6e-09 35.6 19.3 2.2 1 1 0 1 1 1 1 Nucleoside transporter Myb_DNA-binding PF00249.31 EST45521.1 - 8.5e-17 61.1 1.6 5.2e-12 45.8 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST45521.1 - 4.4e-15 55.7 1.2 6.4e-09 35.9 0.2 2.7 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 EST45521.1 - 0.0023 18.0 8.0 0.061 13.4 0.1 3.1 2 1 1 3 3 3 1 SLIDE Rap1_C PF11626.8 EST45521.1 - 0.099 12.7 1.1 0.26 11.4 0.3 2.0 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain VSP PF03302.13 EST45522.1 - 1.8e-05 23.8 173.4 0.2 10.5 20.8 7.9 1 1 6 7 7 7 6 Giardia variant-specific surface protein Insulin_TMD PF17870.1 EST45522.1 - 0.092 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Podoplanin PF05808.11 EST45522.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Podoplanin EF-hand_7 PF13499.6 EST45523.1 - 1.3e-12 48.0 0.6 4.2e-12 46.3 0.6 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_13 PF17958.1 EST45523.1 - 9.7e-11 41.3 0.2 2.6e-08 33.6 0.0 3.5 3 1 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 EST45523.1 - 8e-07 28.2 1.5 5.9e-05 22.3 0.9 3.0 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 EST45523.1 - 5.2e-05 22.9 2.4 0.0002 21.0 0.8 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 EST45523.1 - 0.0011 18.7 1.5 0.031 14.1 0.7 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 EST45523.1 - 0.0037 16.7 1.7 0.075 12.6 0.1 2.9 3 0 0 3 3 3 1 EF hand TMEM239 PF15841.5 EST45523.1 - 0.03 14.2 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 239 family CCSMST1 PF15013.6 EST45526.1 - 0.18 12.0 1.7 0.24 11.6 0.3 2.1 1 1 1 2 2 2 0 CCSMST1 family VSP PF03302.13 EST45529.1 - 6e-10 38.5 94.0 0.0017 17.3 27.1 5.0 1 1 4 5 5 5 4 Giardia variant-specific surface protein Podoplanin PF05808.11 EST45529.1 - 0.37 10.9 4.1 0.39 10.8 0.9 2.2 2 0 0 2 2 2 0 Podoplanin DUF2298 PF10060.9 EST45530.1 - 0.015 14.0 0.0 0.018 13.8 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) VSP PF03302.13 EST45531.1 - 0.38 9.6 195.2 0.1 11.4 24.8 7.3 1 1 5 6 6 6 0 Giardia variant-specific surface protein DUF3799 PF12684.7 EST45532.1 - 0.021 14.6 5.5 0.033 14.0 5.5 1.4 1 1 0 1 1 1 0 PDDEXK-like domain of unknown function (DUF3799) UTP15_C PF09384.10 EST45532.1 - 0.083 12.6 0.2 0.13 11.9 0.2 1.3 1 0 0 1 1 1 0 UTP15 C terminal VSP PF03302.13 EST45535.1 - 0.00042 19.3 157.1 0.014 14.3 20.1 6.7 1 1 5 7 7 7 7 Giardia variant-specific surface protein Insulin_TMD PF17870.1 EST45535.1 - 0.063 13.4 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF4366 PF14283.6 EST45535.1 - 0.2 11.7 1.1 0.51 10.4 1.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) FHIPEP PF00771.20 EST45535.1 - 0.56 8.6 1.6 0.75 8.2 1.6 1.1 1 0 0 1 1 1 0 FHIPEP family CYYR1 PF10873.8 EST45536.1 - 0.0058 17.1 2.0 0.0058 17.1 2.0 1.5 1 1 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 Elf1 PF05129.13 EST45536.1 - 4.7 7.3 10.0 2.2 8.4 7.7 1.6 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like MIT_C PF16565.5 EST45538.1 - 0.019 15.0 0.1 0.024 14.6 0.1 1.2 1 0 0 1 1 1 0 Phospholipase D-like domain at C-terminus of MIT DUF4231 PF14015.6 EST45540.1 - 9.6 6.7 13.1 0.093 13.2 3.1 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF4231) zf-CHY PF05495.12 EST45544.1 - 3.1e-15 56.4 21.1 3.1e-15 56.4 21.1 4.0 2 1 1 3 3 3 1 CHY zinc finger zf-C3HC4_2 PF13923.6 EST45544.1 - 1.7e-07 31.0 7.9 1.7e-07 31.0 7.9 5.3 6 1 0 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EST45544.1 - 2.6e-06 27.7 9.1 2.6e-06 27.7 9.1 5.5 4 2 1 5 5 5 2 Ring finger domain zinc_ribbon_6 PF14599.6 EST45544.1 - 0.00013 21.9 0.7 0.00013 21.9 0.7 3.5 2 1 1 3 3 3 1 Zinc-ribbon zf-RING_5 PF14634.6 EST45544.1 - 0.003 17.5 5.3 0.003 17.5 5.3 6.4 4 2 0 4 4 4 1 zinc-RING finger domain Ank_2 PF12796.7 EST45545.1 - 8.7e-24 83.9 5.9 5.6e-09 36.5 0.2 2.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EST45545.1 - 9.9e-09 35.3 0.1 0.027 14.9 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 EST45545.1 - 1.1e-07 32.3 0.1 0.0038 17.8 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EST45545.1 - 1.3e-07 31.3 0.2 0.031 14.8 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EST45545.1 - 1.4e-07 31.6 0.0 2.2e-05 24.6 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) zf-C3HC4_3 PF13920.6 EST45546.1 - 2.4e-07 30.5 13.9 4.6e-07 29.6 13.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EST45546.1 - 2.5e-05 24.5 15.8 5.4e-05 23.4 15.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EST45546.1 - 0.00059 19.7 16.5 0.0015 18.5 15.7 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EST45546.1 - 0.0011 18.8 15.9 0.0027 17.5 15.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EST45546.1 - 0.0022 17.8 12.9 0.0046 16.8 12.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EST45546.1 - 0.014 15.3 16.4 0.037 13.9 16.4 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EST45546.1 - 0.024 14.7 17.7 0.072 13.1 17.7 1.9 1 0 0 1 1 1 0 RING-type zinc-finger HalX PF08663.10 EST45546.1 - 0.055 13.8 3.4 0.64 10.4 0.2 2.9 2 0 0 2 2 2 0 HalX domain Tropomyosin PF00261.20 EST45546.1 - 0.16 11.4 12.0 0.12 11.7 1.1 3.6 3 0 0 3 3 3 0 Tropomyosin ApoO PF09769.9 EST45546.1 - 2.3 8.2 8.8 12 5.8 1.9 3.4 3 0 0 3 3 3 0 Apolipoprotein O Rx_N PF18052.1 EST45546.1 - 2.7 8.3 7.6 0.94 9.8 0.2 3.1 3 0 0 3 3 2 0 Rx N-terminal domain Mt_ATP-synt_D PF05873.12 EST45546.1 - 3.7 7.4 13.4 1.7 8.4 0.1 3.9 4 0 0 4 4 4 0 ATP synthase D chain, mitochondrial (ATP5H) zf-rbx1 PF12678.7 EST45546.1 - 3.8 7.9 11.6 14 6.1 11.6 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain ABC_tran_CTD PF16326.5 EST45546.1 - 6.1 7.2 17.7 1.1 9.6 0.7 4.3 5 0 0 5 5 5 0 ABC transporter C-terminal domain Ribosomal_L29 PF00831.23 EST45546.1 - 7.9 6.5 11.1 16 5.5 0.6 3.5 3 0 0 3 3 3 0 Ribosomal L29 protein Synaptobrevin PF00957.21 EST45547.1 - 0.0028 17.4 4.1 0.0028 17.4 4.1 1.9 1 1 1 2 2 2 1 Synaptobrevin Spc7 PF08317.11 EST45547.1 - 0.013 14.4 10.2 0.016 14.1 10.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein ATG16 PF08614.11 EST45547.1 - 0.013 15.7 8.2 0.019 15.2 8.2 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Spc24 PF08286.11 EST45547.1 - 0.017 15.4 5.0 0.017 15.4 5.0 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 LXG PF04740.12 EST45547.1 - 0.022 14.5 9.0 0.028 14.1 9.0 1.2 1 0 0 1 1 1 0 LXG domain of WXG superfamily DALR_2 PF09190.11 EST45547.1 - 0.041 14.4 2.8 1.1 9.8 0.1 2.9 1 1 2 3 3 3 0 DALR domain Phage_GPO PF05929.11 EST45547.1 - 0.052 13.2 7.7 0.07 12.7 7.7 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4407 PF14362.6 EST45547.1 - 0.088 12.1 4.9 0.11 11.9 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CM_2 PF01817.21 EST45547.1 - 0.09 13.1 4.9 5.1 7.5 0.4 2.5 1 1 1 2 2 2 0 Chorismate mutase type II APG6_N PF17675.1 EST45547.1 - 0.25 11.9 9.7 0.44 11.1 9.7 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Baculo_p24 PF05073.12 EST45547.1 - 0.28 11.0 8.9 0.67 9.7 8.9 1.7 1 1 0 1 1 1 0 Baculovirus P24 capsid protein DUF948 PF06103.11 EST45547.1 - 0.6 10.4 8.7 5.1 7.4 8.7 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Glyco_transf_41 PF13844.6 EST45547.1 - 0.61 8.5 5.8 0.73 8.2 5.8 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 41 LMBR1 PF04791.16 EST45547.1 - 1 8.2 4.3 1.1 8.1 4.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein YabA PF06156.13 EST45547.1 - 1.2 9.8 11.3 0.29 11.8 6.3 2.1 1 1 1 2 2 2 0 Initiation control protein YabA Seryl_tRNA_N PF02403.22 EST45547.1 - 2 8.7 13.9 0.16 12.2 6.4 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF349 PF03993.12 EST45547.1 - 2.7 8.3 9.5 0.38 11.1 3.6 2.5 1 1 0 2 2 2 0 Domain of Unknown Function (DUF349) DUF2203 PF09969.9 EST45547.1 - 8.1 7.2 8.7 2.8 8.7 2.9 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) UPF0242 PF06785.11 EST45547.1 - 9.5 6.3 16.5 0.79 9.8 6.2 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus CENP-H PF05837.12 EST45547.1 - 9.8 6.6 15.7 1.1 9.7 9.5 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) zf-RING_2 PF13639.6 EST45548.1 - 1.5e-05 25.2 15.9 1.5e-05 25.2 15.9 3.4 3 0 0 3 3 3 1 Ring finger domain Peptidase_C97 PF05903.14 EST45549.1 - 1.3e-26 93.2 0.0 1.7e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain FKBP_C PF00254.28 EST45550.1 - 6.1e-26 90.6 0.1 1.3e-25 89.5 0.1 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 EST45550.1 - 0.00058 20.4 0.3 0.002 18.6 0.0 2.0 2 0 0 2 2 2 1 Nucleoplasmin-like domain Methyltransf_PK PF05891.12 EST45551.1 - 7e-38 130.3 1.1 1.1e-37 129.7 1.1 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_11 PF08241.12 EST45551.1 - 5.4e-05 23.8 0.0 9.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EST45551.1 - 0.00013 22.6 0.1 0.00061 20.4 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EST45551.1 - 0.00095 19.0 0.1 0.0014 18.5 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EST45551.1 - 0.0014 19.4 0.1 0.0074 17.0 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Rsm22 PF09243.10 EST45551.1 - 0.0053 16.1 0.1 0.0095 15.2 0.1 1.5 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 CBM_20 PF00686.19 EST45551.1 - 0.069 13.1 0.4 0.14 12.0 0.4 1.5 1 0 0 1 1 1 0 Starch binding domain OmdA PF13376.6 EST45552.1 - 0.16 12.0 0.4 18 5.5 0.0 2.4 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated RSN1_7TM PF02714.15 EST45554.1 - 5.6e-10 39.0 26.2 5.6e-10 39.0 26.2 1.8 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate DUF2633 PF11119.8 EST45554.1 - 0.2 11.6 4.3 0.97 9.4 4.3 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) Kinesin PF00225.23 EST45556.1 - 3.4e-87 292.5 4.4 3.4e-87 292.5 4.4 2.3 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 EST45556.1 - 8.1e-19 68.0 0.2 8.1e-19 68.0 0.2 3.4 2 1 1 3 3 3 1 Microtubule binding DUF3055 PF11256.8 EST45556.1 - 0.025 14.8 0.2 1.1 9.6 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3055) AAA_22 PF13401.6 EST45556.1 - 3.5 7.9 8.3 20 5.5 0.1 3.3 2 2 0 2 2 2 0 AAA domain EPO_TPO PF00758.18 EST45556.1 - 5 7.1 13.0 0.034 14.2 2.0 2.8 3 0 0 3 3 3 0 Erythropoietin/thrombopoietin Acyl_transf_3 PF01757.22 EST45558.1 - 0.012 14.7 8.7 0.019 14.1 8.7 1.4 1 1 0 1 1 1 0 Acyltransferase family SirB PF04247.12 EST45558.1 - 2.8 8.1 11.8 0.21 11.7 6.3 2.0 2 1 0 2 2 2 0 Invasion gene expression up-regulator, SirB GWT1 PF06423.12 EST45558.1 - 9.9 6.3 12.8 0.73 9.9 0.6 2.9 1 1 2 3 3 3 0 GWT1 DUF2785 PF10978.8 EST45560.1 - 0.12 12.1 4.6 3.4 7.4 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2785) Pro_sub2 PF18513.1 EST45560.1 - 0.85 9.8 8.7 0.73 10.0 0.9 3.8 3 0 0 3 3 3 0 Prodomain subtilisin 2 LRR_9 PF14580.6 EST45561.1 - 0.0059 16.1 0.7 0.032 13.7 0.3 2.2 1 1 1 2 2 2 1 Leucine-rich repeat DUF4139 PF13598.6 EST45563.1 - 0.11 12.2 1.1 0.15 11.7 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) DUF1667 PF07892.11 EST45564.1 - 5.5e-23 80.8 2.3 1.6e-22 79.3 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1667) C_GCAxxG_C_C PF09719.10 EST45566.1 - 0.00054 20.2 0.5 0.06 13.6 0.5 2.4 1 1 0 1 1 1 1 Putative redox-active protein (C_GCAxxG_C_C) SCF PF02404.15 EST45568.1 - 0.014 14.7 0.1 0.017 14.4 0.1 1.1 1 0 0 1 1 1 0 Stem cell factor Peripla_BP_2 PF01497.18 EST45568.1 - 0.13 11.8 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein Viral_cys_rich PF08008.12 EST45570.1 - 0.078 13.0 0.0 0.084 12.9 0.0 1.1 1 0 0 1 1 1 0 Viral cysteine rich Colicin PF01024.19 EST45574.1 - 0.12 12.3 3.9 0.19 11.6 3.9 1.2 1 0 0 1 1 1 0 Colicin pore forming domain Palm_thioest PF02089.15 EST45575.1 - 8.5e-55 186.2 0.0 9.7e-55 186.0 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 EST45575.1 - 5.8e-07 29.3 0.1 1.6e-06 27.8 0.1 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 EST45575.1 - 0.004 16.8 0.2 0.02 14.5 0.1 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.13 EST45575.1 - 0.0049 16.6 0.0 0.037 13.7 0.0 2.2 3 0 0 3 3 3 1 PGAP1-like protein DUF915 PF06028.11 EST45575.1 - 0.0093 15.3 0.2 1.7 7.9 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) UPF0227 PF05728.12 EST45575.1 - 0.012 15.6 0.1 0.019 14.9 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Hydrolase_4 PF12146.8 EST45575.1 - 0.016 14.5 0.0 0.036 13.3 0.0 1.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EST45575.1 - 0.054 13.0 0.1 0.41 10.1 0.0 2.2 3 0 0 3 3 3 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EST45575.1 - 0.074 13.6 0.0 0.13 12.9 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family AAA PF00004.29 EST45577.1 - 1.2e-34 119.5 0.0 2.5e-34 118.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EST45577.1 - 0.00024 21.0 0.6 0.0017 18.3 0.0 2.6 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 EST45577.1 - 0.018 14.9 0.0 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA+ lid domain Viral_helicase1 PF01443.18 EST45577.1 - 0.021 14.6 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_2 PF07724.14 EST45577.1 - 0.024 14.8 0.0 0.075 13.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EST45577.1 - 0.1 12.3 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain S-AdoMet_synt_C PF02773.16 EST45578.1 - 0.32 11.0 2.9 0.25 11.3 0.3 2.1 2 0 0 2 2 2 0 S-adenosylmethionine synthetase, C-terminal domain C5HCH PF17982.1 EST45578.1 - 1.4 9.1 6.1 3.5 7.9 6.1 1.7 1 0 0 1 1 1 0 NSD Cys-His rich domain Arf PF00025.21 EST45579.1 - 1.3e-35 122.4 0.1 1.6e-35 122.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EST45579.1 - 8.2e-15 54.8 0.1 9.3e-15 54.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EST45579.1 - 1.8e-11 44.3 0.1 2.4e-11 43.9 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EST45579.1 - 9.5e-10 38.6 0.1 1.3e-09 38.2 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EST45579.1 - 1.5e-08 34.4 0.2 3.3e-06 26.8 0.2 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EST45579.1 - 2.5e-08 33.6 0.3 2.9e-08 33.3 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EST45579.1 - 1e-07 31.5 0.1 1.3e-07 31.2 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EST45579.1 - 2.3e-05 23.8 4.8 0.00036 19.8 1.7 2.8 1 1 1 2 2 2 1 G-protein alpha subunit FeoB_N PF02421.18 EST45579.1 - 0.00035 20.1 0.2 0.0011 18.5 0.2 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.9 EST45579.1 - 0.0028 17.4 0.9 1.2 8.8 0.2 2.7 2 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 EST45579.1 - 0.0041 17.0 1.9 0.051 13.5 0.2 2.1 1 1 1 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 EST45579.1 - 0.0073 16.6 0.2 0.03 14.6 0.2 1.8 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EST45579.1 - 0.02 15.3 0.0 0.039 14.3 0.0 1.7 1 1 0 1 1 1 0 RNA helicase MeaB PF03308.16 EST45579.1 - 0.088 11.8 0.0 5.7 5.8 0.0 2.3 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 EST45579.1 - 0.13 12.4 0.0 0.32 11.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain Acetyltransf_16 PF05301.11 EST45581.1 - 3.1e-29 102.0 0.4 5.7e-29 101.1 0.4 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase, Mec-17 Acetyltransf_7 PF13508.7 EST45581.1 - 0.058 13.8 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF410 PF04190.13 EST45583.1 - 2.6 7.8 10.3 15 5.2 10.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF410) Ribosomal_L35Ae PF01247.18 EST45585.1 - 3.5e-29 100.8 0.2 4.2e-29 100.5 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L35Ae DKCLD PF08068.12 EST45586.1 - 1.8e-27 95.2 0.0 1.2e-26 92.5 0.1 2.3 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 EST45586.1 - 5.6e-19 69.0 8.2 1.1e-18 68.0 0.2 2.9 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 EST45586.1 - 1.5e-17 63.5 0.3 2.9e-17 62.6 0.3 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 EST45586.1 - 6.1e-17 61.3 0.4 1.3e-16 60.3 0.4 1.6 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 EST45586.1 - 0.00014 22.1 0.2 0.00055 20.1 0.0 2.1 2 0 0 2 2 2 1 UPF0113 PUA domain DUF2828 PF11443.8 EST45586.1 - 2.2 6.3 13.8 3.2 5.7 13.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) RR_TM4-6 PF06459.12 EST45586.1 - 4.3 7.1 20.1 5.7 6.7 20.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 EST45586.1 - 4.8 7.3 9.7 8.8 6.4 9.7 1.4 1 0 0 1 1 1 0 DDHD domain MOZART1 PF12554.8 EST45587.1 - 3.4e-10 39.6 0.1 3.4e-10 39.5 0.1 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated SHIPPO-rpt PF07004.12 EST45589.1 - 0.0016 19.2 3.5 6.7 7.8 0.0 4.7 5 0 0 5 5 5 2 Sperm-tail PG-rich repeat RNA_pol_A_bac PF01000.26 EST45591.1 - 1.5e-11 44.7 0.0 2.3e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EST45591.1 - 4.3e-10 38.9 0.0 6.3e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain TRIF-NTD PF17798.1 EST45592.1 - 0.064 13.3 0.0 0.064 13.3 0.0 1.1 1 0 0 1 1 1 0 TRIF N-terminal domain zf-C2H2 PF00096.26 EST45596.1 - 6.2e-13 48.4 21.2 0.00075 19.8 0.4 4.9 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EST45596.1 - 9.3e-11 41.6 22.8 0.022 15.6 0.3 5.1 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EST45596.1 - 4.2e-07 30.1 0.9 0.066 13.5 0.1 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 EST45596.1 - 2.7e-06 27.5 22.0 5.9e-05 23.3 1.3 5.2 5 1 0 5 5 5 1 Zinc-finger double domain zf-Di19 PF05605.12 EST45596.1 - 7.6e-06 26.1 12.0 0.053 13.8 0.3 3.5 1 1 2 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding zf-C2HE PF16278.5 EST45596.1 - 0.00048 20.5 8.9 0.14 12.6 0.1 3.9 3 1 1 4 4 4 2 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 EST45596.1 - 0.00091 19.5 8.0 0.031 14.7 0.1 3.8 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EST45596.1 - 0.0033 17.7 7.0 2.3 8.6 0.3 3.8 1 1 3 4 4 4 1 C2H2 type zinc-finger (2 copies) zinc_ribbon_15 PF17032.5 EST45596.1 - 0.014 16.1 6.4 0.23 12.2 0.4 3.1 3 0 0 3 3 3 0 zinc-ribbon family zf_UBZ PF18439.1 EST45596.1 - 0.043 13.4 6.9 1.2 8.8 0.0 3.9 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-CHCC PF10276.9 EST45596.1 - 0.063 13.4 5.4 17 5.6 0.1 4.1 4 0 0 4 4 4 0 Zinc-finger domain Ribosomal_L34e PF01199.18 EST45596.1 - 0.063 13.6 2.0 0.16 12.3 0.8 2.3 1 1 1 2 2 2 0 Ribosomal protein L34e PknG_rubred PF16919.5 EST45596.1 - 0.079 13.1 0.2 0.079 13.1 0.2 3.0 2 1 1 3 3 3 0 Protein kinase G rubredoxin domain zf-C2H2_11 PF16622.5 EST45596.1 - 0.15 11.9 0.1 0.15 11.9 0.1 4.2 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 EST45596.1 - 0.18 11.9 0.1 0.18 11.9 0.1 4.6 5 1 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_9 PF16293.5 EST45596.1 - 0.58 10.0 3.0 15 5.5 0.0 3.3 2 2 2 4 4 4 0 C2H2 type zinc-finger (1 copy) GAGA PF09237.11 EST45596.1 - 0.87 9.4 21.3 0.26 11.1 1.0 4.3 2 1 3 5 5 5 0 GAGA factor zf-HIT PF04438.16 EST45596.1 - 1.7 8.6 19.3 10 6.1 0.1 4.8 5 0 0 5 5 5 0 HIT zinc finger DUF2256 PF10013.9 EST45596.1 - 1.7 8.8 15.4 3.4 7.8 0.1 4.5 5 0 0 5 5 4 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-piccolo PF05715.13 EST45596.1 - 3.3 7.9 12.9 5.2 7.3 1.0 3.5 2 2 1 3 3 3 0 Piccolo Zn-finger DUF4674 PF15719.5 EST45596.1 - 8.9 6.3 6.8 1.5 8.8 0.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4674) TTL PF03133.15 EST45598.1 - 6.2e-53 179.8 0.0 5.2e-52 176.8 0.0 1.9 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 EST45598.1 - 0.00015 21.1 0.0 0.11 11.7 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 EST45598.1 - 0.002 17.5 0.0 0.26 10.5 0.0 2.8 2 1 1 3 3 3 2 YheC/D like ATP-grasp ATP-grasp_3 PF02655.14 EST45598.1 - 0.053 13.6 0.0 1.5 8.8 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp domain TTL PF03133.15 EST45599.1 - 2.1e-10 40.2 0.1 2.9e-10 39.8 0.1 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EST45599.1 - 0.034 13.4 0.0 0.047 12.9 0.0 1.2 1 0 0 1 1 1 0 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EST45599.1 - 0.2 10.9 0.0 0.25 10.6 0.0 1.1 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp HSP20 PF00011.21 EST45601.1 - 0.00019 21.6 1.3 0.00038 20.6 0.0 2.1 2 1 0 2 2 2 1 Hsp20/alpha crystallin family DUF4518 PF15008.6 EST45601.1 - 0.00087 18.6 0.8 0.0011 18.2 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4518) ArsA_HSP20 PF17886.1 EST45601.1 - 0.0059 16.1 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 HSP20-like domain found in ArsA eIF3_subunit PF08597.10 EST45601.1 - 0.34 10.8 9.7 0.41 10.5 9.7 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit FAM176 PF14851.6 EST45601.1 - 3.4 7.3 8.8 5.9 6.5 8.8 1.4 1 0 0 1 1 1 0 FAM176 family Ribosomal_S4e PF00900.20 EST45603.1 - 1.2e-29 102.0 1.5 6.2e-29 99.7 0.2 2.5 2 1 1 3 3 3 1 Ribosomal family S4e RS4NT PF08071.12 EST45603.1 - 2.4e-18 65.9 6.7 6.1e-18 64.6 6.6 1.7 2 0 0 2 2 2 1 RS4NT (NUC023) domain 40S_S4_C PF16121.5 EST45603.1 - 3.3e-13 49.0 0.1 6.1e-13 48.2 0.1 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus S4 PF01479.25 EST45603.1 - 2e-06 27.4 0.1 6e-06 25.9 0.1 1.9 1 0 0 1 1 1 1 S4 domain TolA_bind_tri PF16331.5 EST45605.1 - 0.02 14.9 0.2 0.02 14.9 0.2 4.0 4 1 0 4 4 4 0 TolA binding protein trimerisation Spt5-NGN PF03439.13 EST45605.1 - 0.046 13.6 0.2 0.17 11.8 0.2 2.0 1 0 0 1 1 1 0 Early transcription elongation factor of RNA pol II, NGN section NEAT PF05031.12 EST45605.1 - 0.11 13.1 5.0 0.11 13.1 3.4 1.9 1 1 0 1 1 1 0 Iron Transport-associated domain T6PP_N PF18572.1 EST45605.1 - 1.2 9.0 15.3 0.019 14.8 2.3 3.6 2 2 0 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain CENP-F_leu_zip PF10473.9 EST45605.1 - 9.9 6.2 22.2 1 9.4 8.5 2.9 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HSP20 PF00011.21 EST45606.1 - 0.00019 21.6 1.3 0.00038 20.6 0.0 2.1 2 1 0 2 2 2 1 Hsp20/alpha crystallin family DUF4518 PF15008.6 EST45606.1 - 0.00087 18.6 0.8 0.0011 18.2 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4518) ArsA_HSP20 PF17886.1 EST45606.1 - 0.0059 16.1 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 HSP20-like domain found in ArsA eIF3_subunit PF08597.10 EST45606.1 - 0.34 10.8 9.7 0.41 10.5 9.7 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit FAM176 PF14851.6 EST45606.1 - 3.4 7.3 8.8 5.9 6.5 8.8 1.4 1 0 0 1 1 1 0 FAM176 family FOP_dimer PF09398.10 EST45607.1 - 2.8e-05 24.3 0.0 4.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 FOP N terminal dimerisation domain Aa_trans PF01490.18 EST45611.1 - 1.1e-50 172.5 41.8 1.4e-50 172.3 41.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ETRAMP PF09716.10 EST45611.1 - 1.9 8.6 5.5 2.5 8.2 1.5 3.3 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Myb_DNA-binding PF00249.31 EST45612.1 - 4.9e-07 29.8 0.0 7.4e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST45612.1 - 4.2e-06 26.9 0.3 7.3e-06 26.1 0.3 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF4116 PF13475.6 EST45612.1 - 0.005 16.5 0.0 0.088 12.6 0.0 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4116) TEA PF01285.18 EST45612.1 - 0.064 13.3 4.2 0.12 12.4 2.8 2.1 2 1 0 2 2 2 0 TEA/ATTS domain ETRAMP PF09716.10 EST45613.1 - 0.11 12.6 1.2 0.26 11.4 1.2 1.6 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Sema PF01403.19 EST45614.1 - 0.082 11.7 0.5 0.083 11.7 0.5 1.0 1 0 0 1 1 1 0 Sema domain ABC_tran_CTD PF16326.5 EST45615.1 - 0.1 12.9 2.8 1.3 9.4 0.8 2.1 1 1 0 2 2 2 0 ABC transporter C-terminal domain Tox-REase-3 PF15647.6 EST45616.1 - 0.012 15.8 1.0 2.3 8.6 0.4 2.4 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 3 Conotoxin PF02950.17 EST45617.1 - 0.21 12.6 1.3 1.7 9.7 0.3 3.2 2 0 0 2 2 2 0 Conotoxin DUF1836 PF08876.11 EST45618.1 - 0.045 13.8 0.2 0.058 13.4 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1836) Fer2 PF00111.27 EST45619.1 - 7.7e-07 29.0 0.1 1e-06 28.6 0.1 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain ABC_tran PF00005.27 EST45623.1 - 2.7e-44 151.0 0.7 3.4e-22 79.4 0.0 3.3 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 EST45623.1 - 1.1e-10 41.8 3.4 0.0021 17.9 0.0 4.4 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EST45623.1 - 1.4e-06 27.9 0.5 0.014 15.1 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EST45623.1 - 2.5e-06 27.5 1.2 0.014 15.3 0.1 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 EST45623.1 - 7.6e-06 26.6 2.9 0.0017 18.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.19 EST45623.1 - 0.00042 19.8 0.1 1.4 8.3 0.0 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EST45623.1 - 0.053 13.6 1.3 12 6.1 0.0 2.9 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_30 PF13604.6 EST45623.1 - 0.086 12.5 0.3 1.6 8.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EST45623.1 - 0.11 12.5 4.2 2.8 7.8 0.2 2.8 3 0 0 3 3 3 0 NACHT domain Roc PF08477.13 EST45623.1 - 0.29 11.4 1.6 3.3 7.9 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Podoplanin PF05808.11 EST45624.1 - 0.0049 17.0 0.1 0.0078 16.3 0.1 1.4 1 0 0 1 1 1 1 Podoplanin VSP PF03302.13 EST45624.1 - 0.024 13.5 85.1 0.68 8.7 21.2 3.9 1 1 1 2 2 2 0 Giardia variant-specific surface protein Rax2 PF12768.7 EST45624.1 - 0.12 11.8 0.1 0.17 11.3 0.1 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity HTH_10 PF04967.12 EST45626.1 - 0.0013 18.5 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 HTH DNA binding domain Fe_dep_repress PF01325.19 EST45626.1 - 0.04 14.1 0.0 0.071 13.3 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_24 PF13412.6 EST45626.1 - 0.07 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF2408 PF10303.9 EST45627.1 - 0.0044 17.6 3.6 0.014 16.0 3.6 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2408) Podoplanin PF05808.11 EST45628.1 - 0.01 15.9 2.9 0.022 14.9 2.9 1.4 1 0 0 1 1 1 0 Podoplanin VSP PF03302.13 EST45628.1 - 4.2 6.1 80.4 3.5 6.4 21.2 3.9 1 1 2 3 3 3 0 Giardia variant-specific surface protein Nucleoporin2 PF04096.14 EST45632.1 - 0.045 13.9 1.8 0.062 13.4 0.1 2.1 3 0 0 3 3 3 0 Nucleoporin autopeptidase Orn_Arg_deC_N PF02784.16 EST45636.1 - 8.5e-54 182.5 0.0 1.1e-53 182.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EST45636.1 - 2.2e-10 40.6 0.0 3e-10 40.2 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain RRM_3 PF08777.11 EST45637.1 - 1.3e-19 70.1 2.4 4.3e-19 68.5 0.2 2.2 2 0 0 2 2 2 1 RNA binding motif La PF05383.17 EST45637.1 - 3.7e-10 39.7 1.4 7.7e-10 38.7 0.4 2.1 2 0 0 2 2 2 1 La domain RRM_1 PF00076.22 EST45637.1 - 7.4e-05 22.5 3.1 0.00012 21.8 0.3 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5024 PF16427.5 EST45637.1 - 0.022 15.1 1.2 0.059 13.7 1.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5024) RNA_pol_Rpb4 PF03874.16 EST45638.1 - 1.5e-06 28.6 1.9 1.8e-06 28.3 1.9 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 SapB_1 PF05184.15 EST45638.1 - 0.15 12.1 2.7 1.1 9.3 0.1 2.5 3 0 0 3 3 3 0 Saposin-like type B, region 1 DEAD PF00270.29 EST45639.1 - 3.4e-35 121.4 2.5 1.3e-34 119.5 0.7 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EST45639.1 - 9.1e-29 100.0 3.6 5.6e-28 97.5 0.1 3.3 4 1 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 EST45639.1 - 3.4e-08 33.7 0.0 6.7e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 EST45639.1 - 0.0017 18.5 0.2 0.0054 16.9 0.1 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain SNF2_N PF00176.23 EST45639.1 - 0.0067 15.2 0.0 0.027 13.2 0.0 1.9 1 1 1 2 2 2 1 SNF2 family N-terminal domain CMS1 PF14617.6 EST45639.1 - 0.033 13.5 0.0 0.063 12.6 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Peripla_BP_3 PF13377.6 EST45639.1 - 0.058 13.7 0.0 0.33 11.3 0.0 2.0 2 0 0 2 2 2 0 Periplasmic binding protein-like domain AAA_22 PF13401.6 EST45639.1 - 0.088 13.1 1.0 0.43 10.8 0.2 2.4 2 1 0 2 2 2 0 AAA domain Pkinase PF00069.25 EST45640.1 - 8e-28 97.5 6.7 3e-27 95.7 6.7 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST45640.1 - 8e-17 61.4 1.4 1.8e-16 60.2 1.3 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EST45640.1 - 1.2e-06 28.0 0.7 1.9e-06 27.4 0.6 1.5 1 1 0 1 1 1 1 Kinase-like tRNA-synt_2 PF00152.20 EST45640.1 - 0.018 14.1 1.2 0.025 13.6 1.2 1.3 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) DUF2178 PF09946.9 EST45640.1 - 0.039 14.1 0.3 0.082 13.1 0.1 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2178) DnaI_N PF07319.11 EST45640.1 - 0.13 12.9 4.0 0.43 11.3 4.0 1.9 1 0 0 1 1 1 0 Primosomal protein DnaI N-terminus Crinivirus_P26 PF07416.11 EST45640.1 - 0.14 11.8 5.0 0.066 12.9 2.9 1.5 2 0 0 2 2 2 0 Crinivirus P26 protein DPPIV_rep PF18811.1 EST45640.1 - 2.5 8.1 7.1 3.3 7.8 0.6 3.0 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) low complexity region MMR1 PF08505.10 EST45641.1 - 0.0015 18.9 7.9 0.0015 18.9 7.9 2.2 2 0 0 2 2 2 2 Mitochondrial Myo2 receptor-related protein DUF3037 PF11236.8 EST45641.1 - 2.5 8.6 10.7 0.48 10.9 2.4 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3037) LRR_4 PF12799.7 EST45642.1 - 6.3e-12 45.5 21.6 3.1e-07 30.6 3.0 6.2 4 1 4 8 8 8 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EST45642.1 - 1.5e-10 40.8 4.0 1.5e-10 40.8 4.0 3.1 4 0 0 4 4 4 1 Leucine-rich repeat IQ PF00612.27 EST45642.1 - 1.7e-09 36.6 28.2 0.00051 19.6 1.7 5.8 6 0 0 6 6 6 4 IQ calmodulin-binding motif LRR_8 PF13855.6 EST45642.1 - 1.5e-07 31.1 5.0 1.5e-07 31.1 5.0 3.7 2 1 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.33 EST45642.1 - 0.23 12.1 10.7 4.4 8.2 0.1 5.6 4 0 0 4 4 4 0 Leucine Rich Repeat DEAD PF00270.29 EST45643.1 - 2.5e-40 138.1 1.3 2.5e-40 138.1 1.3 2.3 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EST45643.1 - 9e-27 93.6 13.7 9.6e-27 93.5 0.1 4.4 4 1 1 5 5 5 2 Helicase conserved C-terminal domain AAA_19 PF13245.6 EST45643.1 - 0.0015 18.9 0.1 0.004 17.5 0.1 2.2 1 1 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 EST45643.1 - 0.0093 15.9 0.2 0.031 14.3 0.0 2.0 2 0 0 2 2 2 1 Flavivirus DEAD domain DUF4541 PF15074.6 EST45644.1 - 1 10.0 8.9 0.15 12.7 0.9 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4541) DASH_Duo1 PF08651.10 EST45646.1 - 0.35 10.7 3.8 1 9.2 3.8 1.9 1 0 0 1 1 1 0 DASH complex subunit Duo1 RRS1 PF04939.12 EST45647.1 - 8.5e-33 113.5 0.6 8.5e-33 113.5 0.6 1.7 1 1 1 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) DUF1202 PF06717.11 EST45648.1 - 0.011 15.2 0.4 0.021 14.3 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) RTBV_P12 PF06361.11 EST45648.1 - 0.019 15.4 1.0 0.25 11.7 0.0 2.5 2 0 0 2 2 2 0 Rice tungro bacilliform virus P12 protein RC-P840_PscD PF10657.9 EST45648.1 - 0.028 14.5 0.5 0.077 13.1 0.0 2.0 2 0 0 2 2 2 0 Photosystem P840 reaction centre protein PscD TANGO2 PF05742.12 EST45649.1 - 0.035 14.2 2.8 0.045 13.8 2.8 1.2 1 0 0 1 1 1 0 Transport and Golgi organisation 2 A2L_zn_ribbon PF08792.10 EST45650.1 - 0.067 12.9 1.6 1.5 8.6 0.2 2.8 2 0 0 2 2 2 0 A2L zinc ribbon domain Pkinase PF00069.25 EST45653.1 - 2.9e-53 180.9 0.0 3.5e-53 180.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST45653.1 - 7.6e-45 153.2 0.0 8.7e-45 153.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EST45653.1 - 6.2e-11 41.7 0.0 1.2e-10 40.8 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EST45653.1 - 1.1e-07 31.5 0.0 3.7e-07 29.8 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.11 EST45653.1 - 0.00045 19.3 2.2 0.00085 18.4 2.1 1.4 1 1 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.23 EST45653.1 - 0.012 15.5 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 EST45653.1 - 0.1 12.2 0.6 5.1 6.7 0.0 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EST45653.1 - 0.13 11.6 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family V-ATPase_H_C PF11698.8 EST45654.1 - 1.7e-21 76.5 0.3 5.5e-21 74.9 0.1 2.0 2 0 0 2 2 2 1 V-ATPase subunit H Arm PF00514.23 EST45654.1 - 0.086 12.9 0.4 2.3 8.4 0.0 3.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Lipase_3 PF01764.25 EST45655.1 - 2.5e-10 40.4 0.0 5.6e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 EST45655.1 - 0.0014 18.4 0.1 0.006 16.3 0.0 1.9 2 0 0 2 2 2 1 PGAP1-like protein Peptidase_C97 PF05903.14 EST45656.1 - 4.1e-28 98.1 0.5 8.2e-28 97.1 0.5 1.5 1 0 0 1 1 1 1 PPPDE putative peptidase domain CSF-1 PF05337.11 EST45656.1 - 0.014 15.5 2.5 0.1 12.7 0.3 2.4 2 0 0 2 2 2 0 Macrophage colony stimulating factor-1 (CSF-1) MP PF01107.18 EST45657.1 - 0.0069 16.0 0.6 0.017 14.7 0.1 1.9 2 0 0 2 2 2 1 Viral movement protein (MP) NHL PF01436.21 EST45658.1 - 4e-14 51.8 9.3 0.0058 16.6 0.1 5.7 5 0 0 5 5 5 4 NHL repeat HypA PF01155.19 EST45658.1 - 0.0045 17.0 0.2 0.017 15.2 0.2 2.0 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C3HC4_2 PF13923.6 EST45659.1 - 1.6e-06 27.8 9.7 2.6e-06 27.2 9.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EST45659.1 - 5.2e-06 26.7 9.1 7.7e-06 26.1 9.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EST45659.1 - 8e-06 25.6 8.3 1.3e-05 25.0 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EST45659.1 - 8.5e-06 25.5 4.8 1.2e-05 25.1 4.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EST45659.1 - 0.0015 18.4 8.4 0.0025 17.8 8.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EST45659.1 - 0.018 15.3 8.0 0.049 13.9 8.0 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EST45659.1 - 0.024 14.8 9.7 0.041 14.0 9.7 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EST45659.1 - 0.028 14.4 5.4 0.028 14.4 5.4 2.2 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.6 EST45659.1 - 0.28 11.0 6.6 1.5 8.7 7.0 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.14 EST45659.1 - 0.48 10.3 2.9 11 5.9 0.9 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif Zn_ribbon_17 PF17120.5 EST45659.1 - 0.5 10.0 5.1 1.2 8.8 5.2 1.6 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type DNA_ligase_ZBD PF03119.16 EST45659.1 - 0.54 10.3 3.7 14 5.9 0.4 2.5 2 1 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zf-P11 PF03854.14 EST45659.1 - 0.87 9.3 6.2 0.22 11.2 2.3 1.9 2 0 0 2 2 2 0 P-11 zinc finger zf-RING-like PF08746.11 EST45659.1 - 1.7 9.0 7.8 0.18 12.2 2.5 1.9 2 0 0 2 2 2 0 RING-like domain zf-C3HC4_5 PF17121.5 EST45659.1 - 1.9 8.4 8.9 27 4.7 8.9 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Trm112p PF03966.16 EST45661.1 - 0.00019 21.9 1.7 0.00039 20.9 1.7 1.6 1 1 0 1 1 1 1 Trm112p-like protein zinc_ribbon_4 PF13717.6 EST45661.1 - 0.0088 16.0 0.9 2.3 8.2 0.4 2.5 2 0 0 2 2 2 2 zinc-ribbon domain MCM PF00493.23 EST45662.1 - 1.7e-79 266.1 0.0 3.8e-79 264.9 0.0 1.6 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EST45662.1 - 1.2e-23 83.3 0.2 2.3e-23 82.4 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EST45662.1 - 8.7e-12 45.3 1.0 6.7e-11 42.5 0.4 2.3 2 0 0 2 2 2 1 MCM AAA-lid domain AAA_5 PF07728.14 EST45662.1 - 2.6e-07 30.7 0.0 1e-06 28.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EST45662.1 - 6.2e-07 29.0 0.0 1e-05 25.0 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EST45662.1 - 0.0003 20.6 0.0 0.00078 19.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EST45662.1 - 0.0041 16.9 0.2 0.047 13.4 0.0 2.8 3 1 0 3 3 3 1 Sigma-54 interaction domain AAA PF00004.29 EST45662.1 - 0.0097 16.3 0.0 0.031 14.7 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 EST45662.1 - 0.023 14.5 0.1 0.051 13.4 0.1 1.5 1 0 0 1 1 1 0 AAA lid domain AAA_16 PF13191.6 EST45662.1 - 0.057 13.8 0.3 26 5.2 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain AAA_2 PF07724.14 EST45662.1 - 0.068 13.3 0.1 0.16 12.0 0.1 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) FKBP_C PF00254.28 EST45663.1 - 1.2e-27 96.0 0.0 2.4e-27 95.1 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 EST45663.1 - 0.00016 21.3 1.5 1.4 8.9 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EST45663.1 - 0.001 19.0 1.1 0.3 11.3 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat Rapsyn_N PF10579.9 EST45663.1 - 0.0096 16.0 0.9 2.5 8.3 0.2 2.7 1 1 1 2 2 2 2 Rapsyn N-terminal myristoylation and linker region SIR2 PF02146.17 EST45664.1 - 0.33 10.9 1.6 0.47 10.4 1.6 1.2 1 0 0 1 1 1 0 Sir2 family DUF561 PF04481.12 EST45664.1 - 0.49 9.5 2.7 3.2 6.9 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF561) ZapB PF06005.12 EST45665.1 - 0.031 14.7 0.9 0.031 14.7 0.9 6.8 3 2 2 5 5 5 0 Cell division protein ZapB bZIP_1 PF00170.21 EST45665.1 - 0.031 14.4 32.4 0.13 12.4 0.9 6.6 5 1 2 7 7 7 0 bZIP transcription factor TSC22 PF01166.18 EST45665.1 - 0.17 12.3 32.7 0.4 11.0 4.7 7.2 6 2 2 8 8 8 0 TSC-22/dip/bun family DUF4201 PF13870.6 EST45665.1 - 0.23 11.2 48.0 0.14 11.9 15.8 3.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) HAP1_N PF04849.13 EST45665.1 - 0.38 9.9 61.3 0.17 11.0 5.1 3.3 1 1 2 3 3 3 0 HAP1 N-terminal conserved region CALCOCO1 PF07888.11 EST45665.1 - 0.9 8.3 53.9 0.055 12.3 40.4 2.9 1 1 2 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like Spc7 PF08317.11 EST45665.1 - 1.6 7.6 64.9 1.7 7.4 11.7 4.1 2 1 2 4 4 4 0 Spc7 kinetochore protein APG6_N PF17675.1 EST45665.1 - 3.7 8.1 63.6 1.3 9.5 26.2 5.2 2 1 2 4 4 4 0 Apg6 coiled-coil region APC_N_CC PF16689.5 EST45665.1 - 6.5 6.9 23.2 0.57 10.3 3.6 4.3 4 1 1 5 5 5 0 Coiled-coil N-terminus of APC, dimerisation domain Spc24 PF08286.11 EST45665.1 - 7.5 6.8 56.2 0.16 12.3 0.9 6.8 3 1 3 6 6 6 0 Spc24 subunit of Ndc80 EB1 PF03271.17 EST45666.1 - 1.4e-09 38.1 0.1 3.3e-09 36.8 0.1 1.7 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 EST45666.1 - 1e-08 35.3 1.4 1.8e-08 34.5 1.4 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EST45666.1 - 0.042 13.7 0.1 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 CAMSAP CH domain Imm70 PF15601.6 EST45666.1 - 0.059 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 70 NRBF2 PF08961.10 EST45667.1 - 0.017 14.7 9.4 0.017 14.7 9.4 3.9 1 1 2 4 4 4 0 Nuclear receptor-binding factor 2, autophagy regulator DUF2316 PF10078.9 EST45667.1 - 0.039 14.2 1.4 0.039 14.2 1.4 3.8 2 2 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2316) PFK PF00365.20 EST45668.1 - 1.9e-34 119.3 0.0 3.3e-34 118.5 0.0 1.5 1 1 0 1 1 1 1 Phosphofructokinase Ras PF00071.22 EST45669.1 - 3.5e-36 124.3 4.6 1.1e-35 122.7 4.6 1.8 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EST45669.1 - 2.3e-25 89.2 1.6 9.2e-25 87.2 1.6 2.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Fibrinogen_BP PF08017.11 EST45669.1 - 3.1e-16 58.8 25.3 4.9e-16 58.2 25.3 1.3 1 0 0 1 1 1 1 Fibrinogen binding protein Cornifin PF02389.15 EST45669.1 - 1.8e-12 47.6 31.7 2.1e-07 31.2 11.7 2.7 2 1 1 3 3 3 2 Cornifin (SPRR) family Arf PF00025.21 EST45669.1 - 7.9e-10 38.5 0.4 2e-09 37.1 0.4 1.7 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EST45669.1 - 6.8e-07 29.4 0.3 2.8e-06 27.4 0.3 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase TniB PF05621.11 EST45669.1 - 0.0078 15.6 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein AF-4 PF05110.13 EST45669.1 - 0.49 8.4 41.0 0.58 8.2 41.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein PseudoU_synth_1 PF01416.20 EST45670.1 - 3.5e-11 43.5 0.1 2.5e-06 27.9 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase WD40 PF00400.32 EST45671.1 - 0.0071 17.2 1.5 0.038 14.9 0.2 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat tRNA-synt_1 PF00133.22 EST45672.1 - 8.6e-180 598.9 0.1 1.3e-178 595.1 0.1 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EST45672.1 - 3.2e-27 95.4 1.2 7.3e-27 94.2 1.2 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EST45672.1 - 3.3e-13 49.2 1.9 2.4e-06 26.6 0.0 3.6 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 EST45672.1 - 7.2e-08 32.2 0.1 1.4e-06 27.9 0.0 2.5 1 1 1 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 EST45672.1 - 0.00093 18.6 0.1 1.9 7.8 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.25 EST45672.1 - 0.012 14.9 0.0 0.059 12.7 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) tRNA-synt_1c PF00749.21 EST45672.1 - 0.043 12.7 0.5 4.1 6.2 0.1 2.6 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain PCC_BT PF18140.1 EST45672.1 - 0.16 12.3 0.3 1.4 9.3 0.0 2.5 3 0 0 3 3 3 0 Propionyl-coenzyme A carboxylase BT domain Redoxin PF08534.10 EST45674.1 - 5.6e-14 52.1 0.0 8.1e-08 32.1 0.0 2.1 2 0 0 2 2 2 2 Redoxin AhpC-TSA PF00578.21 EST45674.1 - 3e-11 43.3 0.1 0.00023 21.1 0.1 2.2 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin PF00085.20 EST45674.1 - 4.3e-10 39.5 0.4 7.8e-07 29.0 0.2 2.7 2 1 1 3 3 3 2 Thioredoxin Thioredoxin_8 PF13905.6 EST45674.1 - 4.8e-10 39.6 0.0 0.0002 21.6 0.1 2.3 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.6 EST45674.1 - 3.2e-05 23.7 0.6 0.15 11.8 0.3 2.7 1 1 1 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 EST45674.1 - 0.002 18.5 1.0 0.49 10.9 0.2 2.5 2 1 0 2 2 2 1 Thioredoxin-like domain Glutaredoxin PF00462.24 EST45674.1 - 0.0028 17.8 1.5 0.1 12.8 0.0 3.0 2 1 0 2 2 2 1 Glutaredoxin Thioredoxin_3 PF13192.6 EST45674.1 - 0.003 17.6 0.1 3.7 7.7 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin domain TraF PF13728.6 EST45674.1 - 0.0048 16.7 0.4 1.3 8.8 0.1 2.2 2 0 0 2 2 2 2 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 EST45674.1 - 0.0097 16.1 2.2 3.6 7.8 0.2 3.2 3 0 0 3 3 3 1 Thioredoxin-like DUF393 PF04134.12 EST45674.1 - 0.026 15.9 0.0 2.4 9.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF393 RHD_dimer PF16179.5 EST45674.1 - 0.053 13.5 0.0 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 Rel homology dimerisation domain PSI PF01437.25 EST45676.1 - 3.2e-08 34.0 51.7 0.0079 16.7 5.2 5.7 3 2 2 5 5 5 5 Plexin repeat Ank_2 PF12796.7 EST45678.1 - 8.9e-20 71.1 4.2 1.4e-08 35.2 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EST45678.1 - 5.3e-10 38.7 0.3 3.8 8.4 0.0 6.0 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 EST45678.1 - 1.6e-08 34.6 0.7 2.2 8.7 0.0 5.3 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 EST45678.1 - 3.5e-08 33.5 0.1 2.9 8.5 0.0 5.6 4 1 1 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 EST45678.1 - 2.5e-07 31.1 1.0 0.31 11.7 0.3 4.3 3 1 2 5 5 5 3 Ankyrin repeats (many copies) DUF2642 PF10842.8 EST45680.1 - 0.017 14.9 0.4 0.034 14.0 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2642) RNA_pol_Rpb5_C PF01191.19 EST45680.1 - 0.083 12.8 0.1 0.13 12.2 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain zf-RING_2 PF13639.6 EST45681.1 - 1.7e-08 34.7 4.9 1.7e-08 34.7 4.9 5.4 3 1 1 4 4 4 1 Ring finger domain zf-CHY PF05495.12 EST45681.1 - 5.5e-08 33.2 23.4 5.5e-08 33.2 23.4 4.3 1 1 1 2 2 2 1 CHY zinc finger zf-RING_5 PF14634.6 EST45681.1 - 2.7e-07 30.4 5.1 2.7e-07 30.4 5.1 6.0 4 2 1 5 5 5 1 zinc-RING finger domain zf-RING_11 PF17123.5 EST45681.1 - 9.5e-06 25.3 3.8 9.5e-06 25.3 3.8 3.8 4 0 0 4 4 4 1 RING-like zinc finger Prok-RING_4 PF14447.6 EST45681.1 - 0.00098 18.9 5.4 0.00098 18.9 5.4 5.8 2 2 3 5 5 5 1 Prokaryotic RING finger family 4 Adap_comp_sub PF00928.21 EST45682.1 - 1.3e-18 67.3 10.7 2.4e-18 66.5 10.7 1.4 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EST45682.1 - 9.6e-05 22.3 3.7 0.00025 21.0 3.7 1.7 1 0 0 1 1 1 1 Clathrin adaptor complex small chain zf-RING_2 PF13639.6 EST45684.1 - 2.1e-11 43.9 24.7 3.8e-09 36.7 10.1 2.5 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.6 EST45684.1 - 4.5e-07 29.6 8.4 4.5e-07 29.6 8.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EST45684.1 - 6.8e-07 29.0 26.8 5.8e-06 26.0 9.9 2.9 1 1 2 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EST45684.1 - 1.5e-06 28.0 26.3 3.1e-06 27.0 10.0 2.5 2 0 0 2 2 2 2 zinc-RING finger domain zf-rbx1 PF12678.7 EST45684.1 - 5e-06 26.7 22.1 0.012 15.9 4.9 2.9 2 1 0 2 2 2 2 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EST45684.1 - 0.00038 20.4 23.3 0.00078 19.4 4.5 3.2 2 1 1 3 3 3 2 RING-type zinc-finger zf-C3HC4 PF00097.25 EST45684.1 - 0.00049 19.9 27.8 0.012 15.4 10.2 2.8 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EST45684.1 - 0.0019 18.0 8.3 0.0019 18.0 8.3 2.7 2 2 0 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 EST45684.1 - 0.0046 16.6 19.3 0.18 11.5 4.9 2.8 2 1 0 2 2 2 2 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 EST45684.1 - 0.015 15.0 24.2 0.053 13.3 8.2 3.3 3 0 0 3 3 3 0 RING-like zinc finger zf-ANAPC11 PF12861.7 EST45684.1 - 2.9 8.0 16.7 6.3 6.9 5.5 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 EST45684.1 - 6.7 7.1 25.7 4.8 7.6 9.9 3.2 2 2 0 2 2 2 0 RING-like domain zf-P11 PF03854.14 EST45684.1 - 7.8 6.3 19.2 0.19 11.4 7.6 2.8 1 1 1 3 3 3 0 P-11 zinc finger DUF4978 PF16349.5 EST45686.1 - 0.016 14.9 0.1 0.034 13.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4978) ThrE PF06738.12 EST45687.1 - 3.2 7.0 11.7 1.4 8.2 8.8 1.7 1 1 1 2 2 2 0 Putative threonine/serine exporter LRR_4 PF12799.7 EST45689.1 - 8.7e-08 32.4 8.1 0.00011 22.5 0.2 4.2 3 1 2 5 5 5 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EST45689.1 - 3.9e-07 29.7 0.1 6.3e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 EST45689.1 - 0.00016 21.4 5.9 0.0021 17.8 1.2 2.8 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 EST45689.1 - 0.22 12.2 4.2 22 6.1 0.0 4.2 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 EST45689.1 - 0.41 10.8 4.9 2.4 8.4 0.1 3.3 3 0 0 3 3 3 0 Leucine Rich repeat Atypical_Card PF18461.1 EST45690.1 - 0.012 15.8 1.8 0.049 13.9 0.3 2.7 2 0 0 2 2 2 0 Atypical caspase recruitment domain Bac_RepA_C PF18008.1 EST45691.1 - 0.054 13.8 0.3 0.084 13.2 0.3 1.6 1 1 0 1 1 1 0 Replication initiator protein A C-terminal domain KH_6 PF15985.5 EST45692.1 - 1.5e-05 25.2 0.0 3.4e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 KH domain CDC73_C PF05179.14 EST45693.1 - 0.024 14.3 1.7 0.03 14.0 1.3 1.4 1 1 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family, C-terminal HMG_CoA_synt_N PF01154.17 EST45694.1 - 0.09 12.6 0.2 16 5.3 0.0 2.3 2 0 0 2 2 2 0 Hydroxymethylglutaryl-coenzyme A synthase N terminal Beta-Casp PF10996.8 EST45695.1 - 4.4e-19 68.8 0.0 4.3e-18 65.6 0.0 2.5 3 0 0 3 3 3 1 Beta-Casp domain Lactamase_B_6 PF16661.5 EST45695.1 - 1.7e-18 66.8 0.0 3.7e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 EST45695.1 - 1.5e-14 53.7 0.0 3.7e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Beta_lactamase3 PF17030.5 EST45695.1 - 9.5e-10 38.1 0.3 2.6e-09 36.6 0.0 1.9 2 0 0 2 2 2 1 Putative beta-lactamase-like family Lactamase_B_2 PF12706.7 EST45695.1 - 1.4e-08 34.5 0.2 7.1e-06 25.7 0.0 2.6 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EST45695.1 - 9.1e-07 29.1 0.0 3.8e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 EST45695.1 - 0.00019 21.4 0.1 0.00097 19.1 0.1 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain RTP1_C1 PF10363.9 EST45697.1 - 0.0023 18.1 0.4 0.0076 16.4 0.4 1.9 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 1 TPR_1 PF00515.28 EST45698.1 - 0.0002 21.0 1.5 11 6.1 0.1 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EST45698.1 - 0.00031 20.6 1.4 2.7 8.3 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EST45698.1 - 0.0009 19.5 0.2 0.002 18.4 0.2 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat DUF627 PF04781.12 EST45698.1 - 0.013 15.5 0.1 0.037 14.0 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF627) TPR_7 PF13176.6 EST45698.1 - 0.041 13.9 0.5 28 5.0 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DNA_pol_E_B PF04042.16 EST45699.1 - 3.2e-06 26.6 0.6 6.2e-06 25.7 0.6 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B NRDE-2 PF08424.10 EST45700.1 - 0.013 14.6 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference SAM_4 PF18017.1 EST45701.1 - 0.047 13.7 0.1 0.17 11.9 0.1 2.0 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) TetR_C_2 PF08361.11 EST45701.1 - 8.9 6.4 14.9 0.49 10.5 1.7 3.7 2 1 0 3 3 3 0 MAATS-type transcriptional repressor, C-terminal region Metallophos PF00149.28 EST45702.1 - 3.4e-33 115.9 0.0 4.8e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 EST45702.1 - 0.026 13.9 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) Metallophos_2 PF12850.7 EST45702.1 - 0.032 14.4 0.0 0.046 13.9 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain RNA_pol_A_bac PF01000.26 EST45704.1 - 1.6e-22 80.0 0.1 5.4e-22 78.3 0.0 1.9 2 1 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EST45704.1 - 2.2e-10 39.8 0.0 5.6e-10 38.5 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain EF-hand_13 PF17958.1 EST45705.1 - 4.5e-17 61.6 0.1 1.4e-16 60.1 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 EST45705.1 - 3.4e-11 43.4 11.0 5.4e-08 33.2 4.0 4.5 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 EST45705.1 - 4.9e-05 22.6 3.2 0.0031 16.9 0.6 3.5 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.6 EST45705.1 - 0.00036 20.2 6.3 0.32 11.1 0.5 4.8 4 0 0 4 4 4 1 EF-hand domain NifW PF03206.14 EST45705.1 - 0.041 14.4 0.0 0.11 13.0 0.0 1.8 1 0 0 1 1 1 0 Nitrogen fixation protein NifW EF-hand_8 PF13833.6 EST45705.1 - 0.06 13.2 4.6 0.6 10.0 1.0 3.8 4 0 0 4 4 4 0 EF-hand domain pair Jnk-SapK_ap_N PF09744.9 EST45706.1 - 0.0012 19.1 35.8 0.14 12.4 16.4 2.8 1 1 2 3 3 3 2 JNK_SAPK-associated protein-1 Baculo_gp64 PF03273.13 EST45706.1 - 0.022 13.6 2.7 0.032 13.1 2.7 1.2 1 0 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family Cep57_CLD PF14073.6 EST45706.1 - 0.022 14.8 30.4 0.041 13.9 30.4 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 ADIP PF11559.8 EST45706.1 - 0.036 14.1 38.2 0.076 13.1 10.2 3.5 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Rol_Rep_N PF18106.1 EST45706.1 - 0.041 14.2 4.4 0.062 13.6 0.1 3.2 1 1 3 4 4 4 0 Rolling Circle replication initiation protein N-terminal domain TMCO5 PF14992.6 EST45706.1 - 0.095 12.3 28.2 4.1 6.9 28.7 2.1 1 1 1 2 2 2 0 TMCO5 family CENP-F_leu_zip PF10473.9 EST45706.1 - 0.32 11.0 32.1 0.56 10.2 17.4 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.8 EST45706.1 - 0.74 7.3 32.7 0.97 6.9 32.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) APG6_N PF17675.1 EST45706.1 - 0.97 10.0 38.7 1.4 9.5 20.0 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region bZIP_1 PF00170.21 EST45706.1 - 1.8 8.7 23.1 0.33 11.1 1.8 3.7 3 1 0 3 3 3 0 bZIP transcription factor PRKG1_interact PF15898.5 EST45706.1 - 3.6 8.6 32.8 18 6.3 10.1 3.3 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain JIP_LZII PF16471.5 EST45706.1 - 4.7 7.4 13.0 1.6 9.0 0.5 3.6 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II TPR_MLP1_2 PF07926.12 EST45706.1 - 6.1 6.9 38.7 1.2 9.2 21.5 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Lebercilin PF15619.6 EST45706.1 - 6.4 6.4 34.8 12 5.5 17.7 2.9 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Dynein_light PF01221.18 EST45707.1 - 1e-33 115.5 0.7 1.1e-33 115.4 0.7 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 ABC_tran PF00005.27 EST45708.1 - 1.3e-44 152.0 3.5 4.6e-22 79.0 0.1 3.7 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 EST45708.1 - 5.3e-21 75.7 14.8 2.9e-08 33.9 1.1 5.2 4 1 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EST45708.1 - 6.5e-07 29.4 6.3 0.0062 16.5 0.2 3.0 3 0 0 3 3 3 2 RsgA GTPase SMC_N PF02463.19 EST45708.1 - 2.3e-06 27.2 7.2 0.082 12.3 0.2 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EST45708.1 - 8.7e-05 22.2 0.5 0.42 10.4 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 EST45708.1 - 0.0012 19.1 0.3 0.78 10.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EST45708.1 - 0.0017 18.4 1.0 1.1 9.4 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 EST45708.1 - 0.0026 18.3 0.2 0.0026 18.3 0.2 5.0 4 2 1 5 5 3 2 AAA domain Dynamin_N PF00350.23 EST45708.1 - 0.0059 16.7 0.1 2.8 8.0 0.0 3.0 2 0 0 2 2 2 1 Dynamin family PduV-EutP PF10662.9 EST45708.1 - 0.0088 15.8 0.3 3.7 7.3 0.1 3.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation T2SSE PF00437.20 EST45708.1 - 0.012 14.6 1.2 0.081 12.0 0.1 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_16 PF13191.6 EST45708.1 - 0.025 15.0 0.0 10 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 EST45708.1 - 0.025 15.1 0.0 14 6.3 0.0 3.0 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 EST45708.1 - 0.027 13.4 0.0 0.65 8.9 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 EST45708.1 - 0.039 14.4 0.0 4.5 7.7 0.0 3.3 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.6 EST45708.1 - 0.039 14.2 6.1 0.38 11.0 0.3 3.5 3 1 0 3 3 2 0 AAA domain IstB_IS21 PF01695.17 EST45708.1 - 0.044 13.5 1.7 5.8 6.6 0.0 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein ATP-synt_ab PF00006.25 EST45708.1 - 0.044 13.4 0.8 0.46 10.1 0.2 2.4 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.6 EST45708.1 - 0.17 12.1 0.0 27 4.9 0.2 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EST45708.1 - 0.69 9.8 3.3 13 5.7 0.2 2.6 2 0 0 2 2 2 0 NACHT domain MFS_1 PF07690.16 EST45709.1 - 6.4e-33 114.1 9.7 2.1e-26 92.7 0.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATPase_gene1 PF09527.10 EST45709.1 - 3.5 7.9 10.4 1.6 8.9 0.7 3.4 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Ribosomal_L3 PF00297.22 EST45710.1 - 3.6e-128 427.7 0.3 4.1e-128 427.5 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 PRKCSH-like PF12999.7 EST45711.1 - 0.03 14.1 4.6 0.092 12.5 4.6 1.9 1 1 0 1 1 1 0 Glucosidase II beta subunit-like DUF3398 PF11878.8 EST45711.1 - 0.036 14.5 4.4 0.15 12.5 4.4 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3398) Pyr_redox_2 PF07992.14 EST45712.1 - 3.9e-44 151.1 1.3 4.7e-44 150.8 1.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EST45712.1 - 1.2e-21 77.3 11.1 4.4e-18 65.6 5.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EST45712.1 - 2.1e-19 69.8 7.7 1.9e-14 54.0 1.8 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EST45712.1 - 1.7e-12 47.6 1.6 0.00014 21.6 0.1 3.6 3 1 1 4 4 4 3 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EST45712.1 - 3.3e-07 30.4 0.0 0.0079 16.4 0.0 2.8 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain Pyr_redox_dim PF02852.22 EST45712.1 - 6.6e-07 29.6 0.0 2.3e-06 27.8 0.0 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain HI0933_like PF03486.14 EST45712.1 - 1e-05 24.5 4.4 0.5 9.0 0.0 4.0 4 0 0 4 4 4 3 HI0933-like protein NAD_binding_9 PF13454.6 EST45712.1 - 1.3e-05 25.3 0.6 0.11 12.5 0.0 3.7 4 0 0 4 4 4 2 FAD-NAD(P)-binding Thi4 PF01946.17 EST45712.1 - 1.6e-05 24.3 0.6 0.094 11.9 0.1 2.5 2 0 0 2 2 2 2 Thi4 family FAD_binding_2 PF00890.24 EST45712.1 - 0.00026 20.2 0.8 0.54 9.3 0.1 2.7 3 0 0 3 3 3 2 FAD binding domain K_oxygenase PF13434.6 EST45712.1 - 0.00043 19.5 2.2 0.043 13.0 0.2 2.8 1 1 2 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 EST45712.1 - 0.00098 18.3 0.1 0.00098 18.3 0.1 4.0 2 2 2 4 4 4 1 Glucose inhibited division protein A Shikimate_DH PF01488.20 EST45712.1 - 0.0014 18.7 0.8 0.007 16.4 0.6 2.2 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 EST45712.1 - 0.0036 16.7 0.9 0.0068 15.8 0.9 1.5 1 1 0 1 1 1 1 ThiF family Lycopene_cycl PF05834.12 EST45712.1 - 0.0048 16.0 0.4 1.7 7.6 0.0 2.6 2 1 0 2 2 2 2 Lycopene cyclase protein 3HCDH_N PF02737.18 EST45712.1 - 0.0068 16.3 0.1 0.0068 16.3 0.1 2.7 3 1 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 EST45712.1 - 0.058 12.2 5.2 0.82 8.4 0.0 3.0 2 1 0 3 3 3 0 Tryptophan halogenase TrkA_N PF02254.18 EST45712.1 - 0.077 13.3 0.4 11 6.3 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain FAD_oxidored PF12831.7 EST45712.1 - 0.091 12.1 8.1 7.5 5.8 0.2 3.8 2 2 2 4 4 4 0 FAD dependent oxidoreductase Fe_hyd_lg_C PF02906.14 EST45714.1 - 1.3e-57 195.2 1.4 1.7e-57 194.9 1.4 1.1 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fer4 PF00037.27 EST45714.1 - 4.2e-10 39.0 18.4 9e-06 25.3 2.7 3.4 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_7 PF12838.7 EST45714.1 - 8.9e-10 39.0 11.2 1.1e-09 38.8 9.2 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 EST45714.1 - 6.8e-09 35.4 20.0 3.8e-06 26.8 3.1 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_21 PF14697.6 EST45714.1 - 7.5e-09 35.6 12.0 7.5e-09 35.6 12.0 2.9 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EST45714.1 - 1e-07 32.8 8.4 0.00082 20.3 1.5 3.4 3 0 0 3 3 3 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 EST45714.1 - 2.8e-05 24.2 10.1 0.0018 18.4 1.4 3.6 4 1 0 4 4 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EST45714.1 - 3.7e-05 23.7 12.3 3.7e-05 23.7 12.3 3.2 3 2 1 4 4 3 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 EST45714.1 - 0.0015 18.5 20.6 0.02 15.0 2.7 3.4 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_13 PF13370.6 EST45714.1 - 0.0019 18.7 8.0 0.67 10.5 0.5 3.1 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_8 PF13183.6 EST45714.1 - 0.0026 18.2 10.1 0.012 16.1 9.5 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 EST45714.1 - 0.0028 18.1 13.4 0.0054 17.1 1.7 3.7 5 0 0 5 5 2 2 4Fe-4S binding domain Fer4_15 PF13459.6 EST45714.1 - 0.0036 18.0 10.1 0.17 12.7 0.8 3.7 3 0 0 3 3 3 2 4Fe-4S single cluster domain Fer4_17 PF13534.6 EST45714.1 - 0.021 15.3 16.8 0.066 13.8 1.7 3.5 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 EST45714.1 - 0.048 14.5 12.5 0.35 11.7 0.3 3.0 3 0 0 3 3 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 EST45714.1 - 0.049 14.6 6.7 0.049 14.6 6.7 3.9 4 0 0 4 4 3 0 4Fe-4S binding domain DUF751 PF05421.11 EST45715.1 - 0.28 11.9 3.4 1.2 9.9 3.4 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF751) DUF5446 PF17522.2 EST45716.1 - 0.029 14.6 0.6 0.029 14.6 0.6 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5446) CdiA_C PF18451.1 EST45716.1 - 0.078 13.2 2.4 0.17 12.2 2.4 1.6 1 0 0 1 1 1 0 Contact-dependent growth inhibition CdiA C-terminal domain DUF1281 PF06924.11 EST45717.1 - 0.065 12.8 0.3 0.23 11.0 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) LRRC37 PF15779.5 EST45717.1 - 1.7 9.0 5.8 0.15 12.4 0.6 1.9 2 0 0 2 2 2 0 Leucine-rich repeat-containing protein 37 family Hydrolase_6 PF13344.6 EST45718.1 - 6.9e-17 61.4 0.0 2.5e-16 59.6 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EST45718.1 - 1.8e-14 53.6 0.0 3e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like DDT PF02791.17 EST45721.1 - 0.028 14.7 1.1 0.028 14.7 1.1 2.6 2 0 0 2 2 2 0 DDT domain FUSC-like PF12805.7 EST45722.1 - 0.12 11.5 2.0 0.13 11.3 2.0 1.1 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS TetR_C_24 PF17932.1 EST45722.1 - 0.16 12.3 0.1 0.29 11.4 0.1 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Rep_fac-A_C PF08646.10 EST45723.1 - 2.4e-08 33.9 0.8 2.4e-08 33.9 0.8 2.9 2 1 1 3 3 3 1 Replication factor-A C terminal domain tRNA_anti-codon PF01336.25 EST45723.1 - 7.7e-08 32.2 0.1 2.1e-06 27.6 0.1 3.0 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 EST45723.1 - 0.011 15.5 2.0 0.08 12.6 0.8 2.7 1 1 1 2 2 2 0 Cell division control protein 24, OB domain 3 DUF223 PF02721.14 EST45723.1 - 0.14 12.5 1.1 0.58 10.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF223 DivIVA PF05103.13 EST45724.1 - 0.077 13.1 4.4 5.6 7.1 0.6 2.7 2 0 0 2 2 2 0 DivIVA protein WD40 PF00400.32 EST45726.1 - 4.3e-10 40.0 0.8 0.00047 20.9 0.0 4.0 5 0 0 5 5 5 2 WD domain, G-beta repeat Sof1 PF04158.14 EST45726.1 - 1.7e-05 25.0 4.0 4.2e-05 23.7 4.0 1.6 1 0 0 1 1 1 1 Sof1-like domain AAA PF00004.29 EST45727.1 - 7e-39 133.3 0.0 1.6e-38 132.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EST45727.1 - 1.8e-16 59.9 0.5 1.7e-14 53.5 0.1 3.0 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 EST45727.1 - 9.1e-10 38.5 0.3 9.1e-10 38.5 0.3 2.5 3 0 0 3 3 1 1 MIT (microtubule interacting and transport) domain RuvB_N PF05496.12 EST45727.1 - 2.1e-06 27.5 0.0 4.5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EST45727.1 - 6.2e-06 25.7 0.7 0.00056 19.2 0.0 2.9 2 1 0 3 3 3 1 TIP49 P-loop domain AAA_2 PF07724.14 EST45727.1 - 1.2e-05 25.5 0.0 3.8e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 EST45727.1 - 3.4e-05 23.9 0.5 0.00013 22.0 0.0 2.3 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 EST45727.1 - 3.7e-05 24.3 0.1 0.00015 22.3 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.14 EST45727.1 - 4.8e-05 23.4 0.2 0.00081 19.4 0.2 2.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EST45727.1 - 7.3e-05 23.2 0.5 0.017 15.5 0.0 2.8 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EST45727.1 - 0.00015 22.0 0.9 0.082 13.2 0.4 3.0 2 1 0 2 2 1 1 AAA domain AAA_24 PF13479.6 EST45727.1 - 0.00033 20.5 2.4 0.012 15.3 0.1 2.5 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 EST45727.1 - 0.00054 19.2 0.2 0.0026 16.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 EST45727.1 - 0.00093 19.4 0.0 0.0021 18.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EST45727.1 - 0.0015 18.5 0.4 1.1 9.2 0.1 3.0 2 1 0 2 2 2 1 NACHT domain AAA_17 PF13207.6 EST45727.1 - 0.003 18.0 0.0 0.0095 16.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EST45727.1 - 0.0048 16.7 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Glu-tRNAGln PF02686.15 EST45727.1 - 0.0055 17.0 0.7 0.021 15.1 0.1 2.3 2 1 0 2 2 2 1 Glu-tRNAGln amidotransferase C subunit Parvo_NS1 PF01057.17 EST45727.1 - 0.0059 15.7 0.0 0.018 14.1 0.0 1.8 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_lid_3 PF17862.1 EST45727.1 - 0.0071 16.1 0.0 0.022 14.5 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain DUF2075 PF09848.9 EST45727.1 - 0.011 15.0 0.0 0.011 15.0 0.0 2.1 3 1 0 3 3 2 0 Uncharacterized conserved protein (DUF2075) TsaE PF02367.17 EST45727.1 - 0.012 15.7 0.0 0.044 13.8 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 EST45727.1 - 0.016 15.1 0.0 0.041 13.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EST45727.1 - 0.02 14.5 0.3 0.61 9.6 0.1 2.3 1 1 1 2 2 2 0 AAA domain Kinesin PF00225.23 EST45727.1 - 0.024 13.6 0.1 0.029 13.3 0.1 1.4 1 0 0 1 1 1 0 Kinesin motor domain ATPase PF06745.13 EST45727.1 - 0.027 13.8 1.1 0.44 9.8 0.0 2.9 2 1 1 3 3 3 0 KaiC Zot PF05707.12 EST45727.1 - 0.029 14.0 0.0 0.7 9.5 0.0 2.5 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) Viral_helicase1 PF01443.18 EST45727.1 - 0.029 14.1 0.0 0.085 12.6 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.14 EST45727.1 - 0.032 13.5 0.4 0.57 9.4 0.1 2.1 1 1 1 2 2 2 0 KAP family P-loop domain CPT PF07931.12 EST45727.1 - 0.036 13.9 0.0 0.093 12.6 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein RNA_helicase PF00910.22 EST45727.1 - 0.048 14.1 0.0 0.21 12.0 0.0 2.3 1 1 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 EST45727.1 - 0.05 13.9 0.0 0.22 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EST45727.1 - 0.051 13.1 0.2 0.32 10.5 0.0 2.3 2 1 0 2 2 2 0 P-loop containing dynein motor region Torsin PF06309.11 EST45727.1 - 0.066 13.3 0.0 0.2 11.7 0.0 1.8 1 1 0 1 1 1 0 Torsin Mg_chelatase PF01078.21 EST45727.1 - 0.072 12.5 0.0 0.25 10.7 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TPR_2 PF07719.17 EST45727.1 - 0.24 11.6 1.3 0.41 10.9 0.1 2.1 2 0 0 2 2 1 0 Tetratricopeptide repeat Nop10p PF04135.12 EST45728.1 - 1.4e-16 60.3 0.9 1.6e-16 60.1 0.9 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family PolC_DP2 PF03833.13 EST45728.1 - 0.027 12.3 0.5 0.025 12.4 0.5 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 LAGLIDADG_WhiA PF14527.6 EST45729.1 - 1.3 9.1 5.2 0.38 10.9 1.3 2.1 2 2 0 2 2 2 0 WhiA LAGLIDADG-like domain zf-RING_9 PF13901.6 EST45729.1 - 3.7 7.5 11.1 0.57 10.1 2.3 2.1 1 1 1 2 2 2 0 Putative zinc-RING and/or ribbon S4 PF01479.25 EST45730.1 - 1.7e-10 40.5 0.0 4e-09 36.0 0.0 2.4 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 EST45730.1 - 0.0065 17.4 1.1 0.016 16.1 1.0 1.8 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain DUF2730 PF10805.8 EST45730.1 - 0.099 12.7 0.4 0.16 12.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) ASH PF15780.5 EST45731.1 - 9.9e-35 118.7 35.8 2.7e-05 24.3 0.1 22.1 25 0 0 25 25 25 9 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 EST45731.1 - 3.4e-11 43.0 17.8 0.017 15.2 0.0 13.7 17 0 0 17 17 17 2 Protein of unknown function (DUF1573) PapD-like PF14874.6 EST45731.1 - 2.1e-09 37.4 3.9 0.3 11.3 0.0 7.7 9 0 0 9 9 9 3 Flagellar-associated PapD-like Motile_Sperm PF00635.26 EST45731.1 - 7.7e-08 32.2 22.7 0.05 13.4 1.2 10.1 11 0 0 11 11 11 4 MSP (Major sperm protein) domain PALP PF00291.25 EST45732.1 - 5.4e-68 229.5 0.2 3.8e-65 220.2 1.5 2.4 3 0 0 3 3 3 2 Pyridoxal-phosphate dependent enzyme Ank_2 PF12796.7 EST45733.1 - 2e-23 82.8 4.0 2.1e-08 34.6 0.2 4.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EST45733.1 - 7.6e-13 48.3 0.3 0.54 10.8 0.0 6.5 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 EST45733.1 - 2.5e-12 46.7 3.3 0.0011 19.3 0.0 5.8 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EST45733.1 - 2.5e-10 39.7 1.1 6.1 7.8 0.0 6.7 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 EST45733.1 - 6.8e-09 36.1 3.7 0.00092 19.7 0.0 4.7 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Mannitol_dh_C PF08125.13 EST45733.1 - 0.013 15.0 1.3 1.9 7.9 0.0 2.5 2 0 0 2 2 2 0 Mannitol dehydrogenase C-terminal domain DS PF01916.17 EST45733.1 - 0.025 13.8 0.2 0.062 12.5 0.2 1.6 1 0 0 1 1 1 0 Deoxyhypusine synthase PolyA_pol PF01743.20 EST45734.1 - 1.8e-25 89.8 0.0 4.4e-25 88.6 0.0 1.7 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 EST45734.1 - 0.021 14.6 0.0 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 Probable RNA and SrmB- binding site of polymerase A Flavokinase PF01687.17 EST45736.1 - 7.9e-28 97.0 0.1 9.2e-28 96.8 0.1 1.0 1 0 0 1 1 1 1 Riboflavin kinase P66_CC PF16563.5 EST45736.1 - 0.0019 17.7 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 Coiled-coil and interaction region of P66A and P66B with MBD2 DUF2824 PF11039.8 EST45736.1 - 0.02 14.9 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2824) VanW PF04294.13 EST45736.1 - 0.093 12.4 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 VanW like protein DUF1664 PF07889.12 EST45737.1 - 0.032 14.3 5.2 1.3 9.1 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Tup_N PF08581.10 EST45737.1 - 0.37 11.1 3.9 0.64 10.4 0.3 3.0 3 0 0 3 3 3 0 Tup N-terminal IL5 PF02025.15 EST45737.1 - 2.1 8.7 6.0 38 4.6 0.6 3.4 2 1 0 3 3 3 0 Interleukin 5 UPF0242 PF06785.11 EST45737.1 - 5.5 7.0 15.7 0.28 11.3 1.8 2.6 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Thi4 PF01946.17 EST45738.1 - 0.13 11.5 0.1 0.3 10.3 0.1 1.5 1 0 0 1 1 1 0 Thi4 family CpeT PF06206.11 EST45738.1 - 6.4 6.7 9.7 0.41 10.6 0.1 3.4 3 0 0 3 3 3 0 CpeT/CpcT family (DUF1001) zf-RING_9 PF13901.6 EST45739.1 - 0.038 14.0 7.3 0.048 13.6 7.3 1.2 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon ABC_tran_CTD PF16326.5 EST45739.1 - 0.78 10.0 7.8 0.67 10.2 0.3 2.4 1 1 1 2 2 2 0 ABC transporter C-terminal domain bZIP_2 PF07716.15 EST45739.1 - 1.1 9.5 6.7 2.2 8.4 0.9 2.9 2 1 0 2 2 2 0 Basic region leucine zipper Shugoshin_N PF07558.11 EST45739.1 - 1.4 8.9 13.3 1.1 9.1 1.1 3.4 3 1 1 4 4 4 0 Shugoshin N-terminal coiled-coil region Fzo_mitofusin PF04799.13 EST45739.1 - 4.2 6.9 10.2 4.5 6.8 1.5 2.3 1 1 1 2 2 2 0 fzo-like conserved region Fe-ADH PF00465.19 EST45740.1 - 3.1e-48 164.4 0.8 1.4e-47 162.3 0.8 1.8 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EST45740.1 - 2.1e-05 24.3 0.0 0.00026 20.8 0.0 2.1 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase MatE PF01554.18 EST45740.1 - 0.12 12.0 0.4 0.22 11.2 0.4 1.4 1 0 0 1 1 1 0 MatE BBS2_N PF14781.6 EST45741.1 - 0.1 12.5 1.3 24 4.9 0.2 3.7 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal PTAC PF06130.12 EST45742.1 - 0.13 12.4 0.1 1.3 9.2 0.0 2.5 2 1 0 2 2 2 0 Phosphate propanoyltransferase Ribosomal_L16 PF00252.18 EST45743.1 - 1.2e-35 122.3 0.1 1.6e-35 122.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e ADK PF00406.22 EST45744.1 - 4.9e-38 130.6 0.0 5.8e-38 130.3 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EST45744.1 - 9.6e-25 87.6 0.0 1.3e-24 87.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EST45744.1 - 2.5e-10 41.0 0.0 4.7e-10 40.1 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EST45744.1 - 0.0051 17.0 0.0 0.019 15.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 EST45744.1 - 0.0064 16.2 0.0 0.0093 15.7 0.0 1.3 1 0 0 1 1 1 1 Cytidylate kinase Thymidylate_kin PF02223.17 EST45744.1 - 0.011 15.5 0.1 2.7 7.6 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase ATP_bind_1 PF03029.17 EST45744.1 - 0.022 14.5 0.1 0.037 13.8 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 EST45744.1 - 0.027 14.4 0.0 0.067 13.1 0.0 1.7 2 0 0 2 2 2 0 NTPase Ploopntkinase3 PF18751.1 EST45744.1 - 0.034 14.0 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 APOC4 PF15119.6 EST45745.1 - 0.048 13.9 0.4 0.072 13.4 0.4 1.4 1 0 0 1 1 1 0 Apolipoprotein C4 Colicin-DNase PF12639.7 EST45746.1 - 1.5 9.7 5.9 0.43 11.4 1.2 2.4 2 1 0 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin DUF3037 PF11236.8 EST45747.1 - 0.026 14.9 0.1 0.1 13.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) Med15_fungi PF05397.12 EST45747.1 - 1.2 9.4 9.9 0.31 11.3 1.6 3.2 2 1 1 3 3 3 0 Mediator complex subunit 15 His_binding PF02098.16 EST45750.1 - 0.27 11.2 6.2 4 7.5 1.1 2.4 2 0 0 2 2 2 0 Tick histamine binding protein Ank_2 PF12796.7 EST45751.1 - 2.6e-25 88.8 5.2 1.4e-09 38.4 0.3 5.2 3 2 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EST45751.1 - 3.3e-15 54.7 3.9 0.15 12.7 0.0 7.5 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 EST45751.1 - 4.5e-15 55.5 1.3 0.0003 21.0 0.0 6.3 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 EST45751.1 - 1.7e-12 47.6 0.4 0.039 14.5 0.0 6.2 5 2 1 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 EST45751.1 - 4.2e-10 39.6 0.2 7.2 7.3 0.0 7.2 7 0 0 7 7 7 2 Ankyrin repeat DUF3368 PF11848.8 EST45751.1 - 0.031 14.1 2.5 13 5.6 0.0 4.2 5 0 0 5 5 5 0 Domain of unknown function (DUF3368) DUF4423 PF14394.6 EST45751.1 - 0.033 13.9 0.1 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) Thioredoxin_6 PF13848.6 EST45752.1 - 0.00017 21.5 9.0 0.0002 21.3 6.4 2.2 1 1 2 3 3 3 1 Thioredoxin-like domain Thioredoxin PF00085.20 EST45752.1 - 0.044 13.8 0.7 1 9.4 0.0 2.8 3 0 0 3 3 3 0 Thioredoxin AP_endonuc_2 PF01261.24 EST45753.1 - 6.2e-16 58.5 0.1 8.1e-16 58.1 0.1 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DUF2124 PF09897.9 EST45753.1 - 0.0021 17.9 0.1 0.0034 17.3 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2124) KH_5 PF13184.6 EST45753.1 - 0.062 13.4 0.4 0.14 12.3 0.2 1.7 2 0 0 2 2 2 0 NusA-like KH domain PHD_2 PF13831.6 EST45757.1 - 4.6e-10 38.9 4.4 4.6e-10 38.9 4.4 3.4 3 0 0 3 3 3 1 PHD-finger zf-HC5HC2H_2 PF13832.6 EST45757.1 - 1.3e-08 35.0 15.0 1.3e-08 35.0 15.0 3.0 3 0 0 3 3 3 1 PHD-zinc-finger like domain PHD PF00628.29 EST45757.1 - 2e-06 27.6 13.1 2e-06 27.6 13.1 3.1 3 0 0 3 3 3 1 PHD-finger Aldo_ket_red PF00248.21 EST45761.1 - 4.5e-36 124.5 2.1 2.7e-34 118.7 2.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Sacchrp_dh_NADP PF03435.18 EST45761.1 - 0.15 12.3 0.1 0.74 10.1 0.0 2.1 2 1 1 3 3 3 0 Saccharopine dehydrogenase NADP binding domain HEAT PF02985.22 EST45764.1 - 0.067 13.5 1.9 9.4 6.8 0.1 4.6 4 0 0 4 4 4 0 HEAT repeat DUF1241 PF06840.11 EST45764.1 - 0.068 12.8 5.7 2.1 8.0 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1241) NopRA1 PF16201.5 EST45764.1 - 4.4 6.8 6.6 2.3 7.8 0.1 3.3 3 0 0 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 STI1 PF17830.1 EST45765.1 - 2.2e-13 49.9 0.4 6.8e-12 45.1 0.1 2.8 3 0 0 3 3 3 1 STI1 domain TPR_1 PF00515.28 EST45765.1 - 1.2e-07 31.3 1.8 0.0011 18.7 0.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EST45765.1 - 3.3e-05 23.7 2.6 0.31 11.3 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EST45765.1 - 0.00035 21.1 0.2 0.0042 17.7 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_22 PF18833.1 EST45765.1 - 0.00053 20.1 1.2 0.1 12.7 0.2 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EST45765.1 - 0.0016 18.1 0.1 0.18 11.5 0.1 2.7 2 0 0 2 2 2 1 TPR repeat TPR_17 PF13431.6 EST45765.1 - 0.01 16.2 0.0 0.045 14.1 0.0 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 EST45765.1 - 0.014 15.6 1.9 0.2 11.8 0.1 3.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 EST45765.1 - 0.058 13.9 3.8 0.8 10.3 0.2 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EST45765.1 - 0.066 13.4 1.2 0.08 13.2 0.1 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EST45765.1 - 0.13 12.6 0.2 0.13 12.6 0.2 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EST45765.1 - 0.23 11.6 0.1 0.23 11.6 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 EST45765.1 - 0.24 11.7 2.5 1.3 9.4 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4407 PF14362.6 EST45765.1 - 3.2 7.0 9.2 4.6 6.5 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DNA_primase_lrg PF04104.14 EST45766.1 - 8.7e-47 159.8 0.4 1.3e-46 159.1 0.4 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit HD PF01966.22 EST45769.1 - 3.3e-12 46.7 0.2 8.9e-12 45.3 0.2 1.8 2 0 0 2 2 2 1 HD domain PTAC PF06130.12 EST45769.1 - 0.021 15.0 0.1 0.11 12.7 0.1 2.2 2 0 0 2 2 2 0 Phosphate propanoyltransferase Replic_Relax PF13814.6 EST45769.1 - 0.12 12.5 0.1 0.21 11.6 0.1 1.3 1 0 0 1 1 1 0 Replication-relaxation DKNYY PF13644.6 EST45769.1 - 4.6 8.0 10.3 59 4.4 10.2 2.5 1 1 0 1 1 1 0 DKNYY family AP_endonuc_2 PF01261.24 EST45770.1 - 1.4e-19 70.4 0.0 2.3e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DUF2124 PF09897.9 EST45770.1 - 0.0049 16.8 0.1 0.0091 15.9 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2124) YppF PF14178.6 EST45770.1 - 0.023 14.5 0.1 0.066 13.1 0.1 1.7 1 0 0 1 1 1 0 YppF-like protein Receptor_2B4 PF11465.8 EST45770.1 - 0.059 13.6 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 PCIF1_WW PF12237.8 EST45773.1 - 3.2e-19 69.2 4.5 7.7e-19 67.9 4.5 1.6 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain UPF0167 PF03691.14 EST45774.1 - 0.47 10.2 7.0 0.35 10.6 5.5 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0167) Arg_decarbox_C PF17944.1 EST45774.1 - 8 7.1 9.9 18 6.0 0.8 3.4 3 1 1 4 4 4 0 Arginine decarboxylase C-terminal helical extension adh_short PF00106.25 EST45775.1 - 1.2e-20 73.9 0.0 1.5e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EST45775.1 - 1.4e-14 54.2 0.0 1.7e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EST45775.1 - 2.4e-08 33.8 0.3 7.8e-08 32.1 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EST45775.1 - 7.2e-06 26.0 0.0 1.3e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EST45775.1 - 0.0014 17.8 0.0 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EST45775.1 - 0.0016 18.4 0.0 0.0028 17.5 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EST45775.1 - 0.0024 17.0 0.0 0.0035 16.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain DUF1776 PF08643.10 EST45775.1 - 0.0076 15.6 0.1 0.01 15.2 0.1 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) F420_oxidored PF03807.17 EST45775.1 - 0.087 13.4 0.0 0.18 12.4 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF4441 PF14536.6 EST45775.1 - 0.95 9.7 10.7 0.21 11.8 5.3 2.3 2 2 0 2 2 2 0 Domain of unknown function (DUF4441) SRPRB PF09439.10 EST45776.1 - 1.4e-08 34.4 0.3 3.9e-08 32.9 0.0 1.7 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit YoaP PF14268.6 EST45776.1 - 0.021 14.3 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 YoaP-like NMT1_3 PF16868.5 EST45776.1 - 0.095 12.1 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 NMT1-like family Helicase_C_2 PF13307.6 EST45777.1 - 8.9e-29 100.8 1.3 1.9e-27 96.5 0.1 3.3 2 2 1 3 3 3 1 Helicase C-terminal domain DEAD_2 PF06733.15 EST45777.1 - 2.5e-19 69.6 10.1 2.5e-19 69.6 10.1 2.4 2 0 0 2 2 2 1 DEAD_2 ResIII PF04851.15 EST45777.1 - 7.4e-05 22.8 5.0 0.0074 16.3 0.0 3.2 3 1 0 3 3 3 2 Type III restriction enzyme, res subunit DEAD PF00270.29 EST45777.1 - 0.00036 20.4 4.1 0.0023 17.8 0.2 3.4 3 1 0 3 3 3 1 DEAD/DEAH box helicase HBB PF06777.11 EST45777.1 - 0.03 14.0 0.1 0.084 12.5 0.1 1.7 1 0 0 1 1 1 0 Helical and beta-bridge domain DEAD PF00270.29 EST45778.1 - 4.3e-13 49.4 0.3 2.9e-12 46.7 0.1 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EST45778.1 - 5.7e-07 29.9 2.5 1.2e-06 28.8 0.2 3.0 2 1 0 2 2 2 1 Helicase conserved C-terminal domain TRADD_N PF09034.10 EST45778.1 - 0.002 18.2 1.7 1.5 8.9 0.0 4.0 4 0 0 4 4 4 2 TRADD, N-terminal domain T2SSE PF00437.20 EST45778.1 - 0.0083 15.2 0.0 0.02 14.0 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 EST45778.1 - 0.048 14.0 0.0 0.23 11.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain HHH_5 PF14520.6 EST45778.1 - 0.09 13.4 0.2 2.2 9.0 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain HD PF01966.22 EST45779.1 - 3e-12 46.8 0.4 8.8e-12 45.3 0.2 1.8 2 0 0 2 2 2 1 HD domain Replic_Relax PF13814.6 EST45779.1 - 0.017 15.2 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 Replication-relaxation HD PF01966.22 EST45780.1 - 1.9e-07 31.3 0.0 3.5e-07 30.5 0.0 1.4 1 1 0 1 1 1 1 HD domain ABC_tran PF00005.27 EST45783.1 - 4e-26 92.2 1.1 8.5e-26 91.1 0.0 2.0 2 0 0 2 2 2 1 ABC transporter ABC2_membrane_3 PF12698.7 EST45783.1 - 7.6e-08 31.8 24.6 7.6e-08 31.8 24.6 2.7 3 0 0 3 3 3 1 ABC-2 family transporter protein AAA_21 PF13304.6 EST45783.1 - 1.2e-07 31.8 2.7 4.3e-06 26.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EST45783.1 - 0.0027 17.2 0.4 0.033 13.6 0.4 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EST45783.1 - 0.027 14.2 0.1 0.027 14.2 0.1 2.5 1 1 1 3 3 3 0 AAA ATPase domain IstB_IS21 PF01695.17 EST45783.1 - 0.09 12.5 0.1 13 5.5 0.1 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein SHIPPO-rpt PF07004.12 EST45785.1 - 0.00035 21.3 7.0 1.9 9.5 0.0 4.2 4 0 0 4 4 4 3 Sperm-tail PG-rich repeat CAF1C_H4-bd PF12265.8 EST45787.1 - 1.2e-07 31.8 1.1 6.7e-07 29.5 0.0 2.4 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EST45787.1 - 0.023 15.6 0.8 1.2 10.2 0.0 3.4 4 0 0 4 4 4 0 WD domain, G-beta repeat PQQ_3 PF13570.6 EST45787.1 - 0.33 11.5 0.8 0.97 10.0 0.2 2.1 2 0 0 2 2 2 0 PQQ-like domain TTL PF03133.15 EST45788.1 - 4.1e-69 232.9 5.3 3e-68 230.1 5.3 2.3 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 EST45788.1 - 8.7e-05 21.9 0.0 0.002 17.5 0.0 2.3 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 EST45788.1 - 0.00052 19.3 0.0 0.00052 19.3 0.0 3.2 3 1 0 3 3 3 1 YheC/D like ATP-grasp ATP-grasp_3 PF02655.14 EST45788.1 - 0.0094 16.0 3.9 0.039 14.0 0.0 2.8 3 0 0 3 3 3 1 ATP-grasp domain RimK PF08443.11 EST45788.1 - 0.011 15.3 0.2 0.46 10.1 0.0 2.6 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Rhomboid PF01694.22 EST45789.1 - 0.0014 18.6 6.5 0.003 17.6 6.5 1.6 1 1 0 1 1 1 1 Rhomboid family SUIM_assoc PF16619.5 EST45789.1 - 0.01 15.8 0.2 0.01 15.8 0.2 1.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DER1 PF04511.15 EST45789.1 - 0.098 12.6 8.4 0.2 11.6 8.4 1.7 1 1 0 1 1 1 0 Der1-like family EF-hand_7 PF13499.6 EST45790.1 - 0.0061 17.0 0.1 1.9 9.0 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EST45790.1 - 0.0067 16.3 0.0 16 5.8 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain MGAT2 PF05060.14 EST45791.1 - 0.62 9.1 7.1 0.18 10.9 2.4 1.9 1 1 1 2 2 2 0 N-acetylglucosaminyltransferase II (MGAT2) SHS2_Rpb7-N PF03876.17 EST45792.1 - 0.0011 19.3 0.0 0.0021 18.4 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 UPF0542 PF15086.6 EST45793.1 - 0.21 11.5 2.9 0.21 11.5 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 PRP1_N PF06424.12 EST45795.1 - 0.016 15.6 0.0 0.022 15.1 0.0 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Thioredoxin_6 PF13848.6 EST45796.1 - 1.4e-07 31.7 7.4 2.9e-07 30.6 7.4 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain ABC2_membrane_3 PF12698.7 EST45796.1 - 0.21 10.6 12.6 1.3e+02 1.4 12.6 2.2 1 1 0 1 1 1 0 ABC-2 family transporter protein Ank_2 PF12796.7 EST45797.1 - 2.8e-14 53.5 0.7 2.4e-08 34.5 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EST45797.1 - 2.6e-06 27.6 0.0 0.04 14.3 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EST45797.1 - 0.0022 18.4 0.0 3.2 8.6 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat NPV_P10 PF05531.12 EST45797.1 - 0.015 15.8 3.1 0.57 10.7 3.1 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein TMF_TATA_bd PF12325.8 EST45797.1 - 0.019 15.2 0.5 0.36 11.1 0.3 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.12 EST45797.1 - 0.024 14.7 8.0 0.085 12.9 1.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 EST45797.1 - 0.33 11.0 6.2 0.19 11.8 3.4 2.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.11 EST45797.1 - 0.76 10.2 11.6 6.6 7.2 0.3 3.8 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) Gag_p10 PF02337.17 EST45798.1 - 0.043 13.7 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Retroviral GAG p10 protein Bromodomain PF00439.25 EST45799.1 - 1.1e-09 38.3 0.3 2.5e-09 37.1 0.1 1.7 1 1 1 2 2 2 1 Bromodomain DUF5099 PF17025.5 EST45799.1 - 0.057 13.8 0.8 0.1 13.0 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5099) Rit1_C PF17184.4 EST45799.1 - 0.15 11.5 0.1 0.2 11.0 0.1 1.2 1 0 0 1 1 1 0 Rit1 N-terminal domain Dscam_C PF12355.8 EST45800.1 - 0.047 14.7 0.2 0.067 14.2 0.2 1.3 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal YqbF PF14553.6 EST45801.1 - 0.023 14.5 0.0 2 8.4 0.0 3.2 3 0 0 3 3 3 0 YqbF, hypothetical protein domain Phage_Integr_2 PF13009.6 EST45804.1 - 0.062 12.4 3.4 0.93 8.5 0.6 2.2 2 0 0 2 2 2 0 Putative phage integrase DUF815 PF05673.13 EST45804.1 - 0.093 11.9 0.0 0.21 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) CD34_antigen PF06365.12 EST45805.1 - 4.5e-06 26.4 1.9 5.3e-06 26.2 1.9 1.0 1 0 0 1 1 1 1 CD34/Podocalyxin family DUF4293 PF14126.6 EST45805.1 - 0.0018 18.5 0.9 0.0025 18.1 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4293) DUF5383 PF17355.2 EST45805.1 - 0.011 16.2 0.6 0.011 16.2 0.6 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5383) PspB PF06667.12 EST45805.1 - 0.023 14.7 1.4 0.031 14.3 0.3 1.8 1 1 1 2 2 2 0 Phage shock protein B DUF4446 PF14584.6 EST45805.1 - 0.023 14.7 0.4 0.023 14.7 0.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) ABC2_membrane_3 PF12698.7 EST45805.1 - 0.075 12.1 0.2 0.075 12.1 0.2 1.5 1 1 1 2 2 2 0 ABC-2 family transporter protein Rhabdo_glycop PF00974.18 EST45805.1 - 0.089 11.2 0.0 0.13 10.7 0.0 1.2 1 1 0 1 1 1 0 Rhabdovirus spike glycoprotein Asp5 PF17000.5 EST45805.1 - 0.16 12.1 1.2 0.28 11.4 1.2 1.4 1 0 0 1 1 1 0 Accessory secretory protein Sec, Asp5 ENT PF03735.14 EST45805.1 - 0.29 11.2 4.0 0.73 9.9 0.6 2.2 2 0 0 2 2 2 0 ENT domain DUF948 PF06103.11 EST45805.1 - 0.5 10.7 3.9 0.39 11.0 0.6 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Fzo_mitofusin PF04799.13 EST45805.1 - 1.4 8.4 5.9 0.48 10.0 0.5 2.3 2 1 1 3 3 3 0 fzo-like conserved region SlyX PF04102.12 EST45805.1 - 3 8.5 11.0 0.24 12.1 2.6 2.7 2 1 1 3 3 3 0 SlyX HP1451_C PF18472.1 EST45808.1 - 0.04 13.9 0.0 0.11 12.5 0.0 1.7 1 1 0 1 1 1 0 HP1451 C-terminal domain Acylphosphatase PF00708.18 EST45809.1 - 2.5e-17 63.0 0.0 2.8e-17 62.9 0.0 1.0 1 0 0 1 1 1 1 Acylphosphatase TbpB_B_D PF01298.18 EST45809.1 - 0.012 16.0 0.1 0.012 16.0 0.1 1.1 1 0 0 1 1 1 0 C-lobe and N-lobe beta barrels of Tf-binding protein B zf-MYND PF01753.18 EST45810.1 - 1.4e-08 34.7 15.1 2.7e-08 33.8 15.1 1.4 1 0 0 1 1 1 1 MYND finger DENN PF02141.21 EST45813.1 - 9.5e-16 58.3 1.5 9.5e-16 58.3 1.5 2.7 3 0 0 3 3 3 1 DENN (AEX-3) domain dDENN PF03455.19 EST45813.1 - 0.0041 17.1 1.8 0.0041 17.1 1.8 2.4 2 0 0 2 2 2 1 dDENN domain uDENN PF03456.18 EST45813.1 - 0.012 16.3 0.7 0.038 14.7 0.7 1.9 1 0 0 1 1 1 0 uDENN domain Aldose_epim PF01263.20 EST45815.1 - 1.9e-53 181.7 0.4 2.2e-53 181.5 0.4 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase PALP PF00291.25 EST45816.1 - 3.4e-58 197.4 0.1 3.9e-58 197.2 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Na_H_Exchanger PF00999.21 EST45819.1 - 1.1e-54 185.7 41.5 1.5e-54 185.3 41.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Adeno_E3_CR2 PF02439.15 EST45819.1 - 0.61 9.9 0.0 0.61 9.9 0.0 3.5 3 1 1 4 4 4 0 Adenovirus E3 region protein CR2 PALP PF00291.25 EST45820.1 - 2.1e-58 198.1 0.1 2.5e-58 197.8 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ogr_Delta PF04606.12 EST45821.1 - 0.063 13.3 1.9 0.14 12.1 1.9 1.7 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger GFRP PF06399.13 EST45821.1 - 0.12 12.2 0.0 0.47 10.4 0.0 2.0 2 0 0 2 2 2 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) Hirudin PF00713.17 EST45821.1 - 0.13 12.6 0.3 0.21 12.0 0.3 1.3 1 0 0 1 1 1 0 Hirudin DUF1398 PF07166.11 EST45822.1 - 0.01 15.9 2.6 0.01 15.9 2.6 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1398) US30 PF17624.2 EST45823.1 - 0.053 12.6 0.0 0.098 11.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function XRN_N PF03159.18 EST45824.1 - 5.4e-78 261.8 0.0 5.4e-78 261.8 0.0 1.9 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 EST45824.1 - 1e-64 219.2 5.8 1.4e-64 218.7 5.8 1.2 1 0 0 1 1 1 1 Xrn1 helical domain Spidroin_N PF16763.5 EST45825.1 - 0.006 16.6 1.0 0.019 15.0 0.5 2.1 2 1 0 2 2 2 1 Major ampullate spidroin 1, spider silk protein 1, N-term DUF2390 PF09523.10 EST45825.1 - 0.13 12.6 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) Baculo_PEP_C PF04513.12 EST45825.1 - 0.15 12.1 2.9 0.49 10.4 2.8 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4061 PF13270.6 EST45825.1 - 0.17 12.2 1.3 0.37 11.1 0.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4061) PRESAN PF09687.10 EST45825.1 - 4.8 7.8 11.3 0.49 10.9 4.9 2.2 2 0 0 2 2 2 0 Plasmodium RESA N-terminal Pkinase PF00069.25 EST45826.1 - 2.3e-39 135.4 0.4 3.9e-38 131.3 0.0 3.2 3 1 0 3 3 3 1 Protein kinase domain APH PF01636.23 EST45826.1 - 1.4e-05 25.2 0.0 0.0016 18.4 0.0 2.4 1 1 0 2 2 2 1 Phosphotransferase enzyme family tRNA_anti_2 PF13742.6 EST45826.1 - 0.028 14.6 1.1 0.34 11.1 0.4 3.0 2 1 0 2 2 2 0 OB-fold nucleic acid binding domain PI_PP_I PF18363.1 EST45826.1 - 1.7 8.9 6.1 0.98 9.6 1.8 3.1 3 0 0 3 3 3 0 Phosphoinositide phosphatase insertion domain ATP-synt_E PF05680.12 EST45826.1 - 4.8 7.6 6.0 6.5 7.2 1.2 2.9 2 0 0 2 2 2 0 ATP synthase E chain MtrG PF04210.13 EST45827.1 - 0.13 12.1 0.3 0.84 9.5 0.3 2.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G IBN_N PF03810.19 EST45828.1 - 0.0072 16.2 0.4 0.014 15.3 0.1 1.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF2935 PF11155.8 EST45829.1 - 0.00033 21.0 0.0 0.043 14.2 0.0 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF2935) DUF4145 PF13643.6 EST45829.1 - 0.028 14.5 1.1 0.087 13.0 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4145) SPT2 PF08243.11 EST45829.1 - 0.62 10.6 4.5 2.4 8.7 4.5 2.0 1 0 0 1 1 1 0 SPT2 chromatin protein RIH_assoc PF08454.11 EST45830.1 - 0.0033 17.3 5.2 0.0033 17.3 5.2 3.5 3 1 0 3 3 3 1 RyR and IP3R Homology associated Fib_alpha PF08702.10 EST45831.1 - 0.0062 16.7 17.9 0.0062 16.7 17.9 13.3 7 4 9 17 17 17 4 Fibrinogen alpha/beta chain family SLC35F PF06027.12 EST45833.1 - 1.4e-19 70.7 25.0 1.9e-19 70.3 25.0 1.1 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 EST45833.1 - 1.2e-09 38.5 41.1 1.1e-07 32.1 17.8 2.4 2 1 0 2 2 2 2 EamA-like transporter family DHHC PF01529.20 EST45834.1 - 6.8e-14 52.1 6.1 6.8e-14 52.1 6.1 2.4 2 0 0 2 2 2 1 DHHC palmitoyltransferase zf-BED PF02892.15 EST45834.1 - 4.1 7.5 11.1 6.5 6.9 0.0 3.6 4 0 0 4 4 4 0 BED zinc finger CO_dh PF02552.16 EST45834.1 - 5.2 6.8 8.2 3.7 7.3 1.6 2.3 2 0 0 2 2 2 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit zf-C2HCIx2C PF10782.9 EST45834.1 - 6.6 6.7 8.4 4 7.4 1.1 2.9 3 0 0 3 3 3 0 Zinc-finger Asp23 PF03780.13 EST45835.1 - 0.75 10.2 7.9 7.2 7.1 1.1 3.4 3 0 0 3 3 3 0 Asp23 family, cell envelope-related function EF1G PF00647.19 EST45836.1 - 4.3e-17 62.1 1.1 7.8e-17 61.3 1.1 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 EST45836.1 - 4.8e-08 33.1 0.1 1.1e-07 32.0 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EST45836.1 - 1.2e-05 25.5 0.0 3.9e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EST45836.1 - 0.0014 18.6 0.0 0.0035 17.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain CagZ PF09053.10 EST45836.1 - 0.0043 16.7 0.2 0.0098 15.5 0.2 1.5 2 0 0 2 2 2 1 CagZ GST_C_6 PF17171.4 EST45836.1 - 0.09 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Asp2 PF16929.5 EST45836.1 - 0.12 11.3 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter E1-E2_ATPase PF00122.20 EST45836.1 - 0.16 11.5 0.9 0.31 10.5 0.9 1.5 1 0 0 1 1 1 0 E1-E2 ATPase HSP70 PF00012.20 EST45839.1 - 2.6e-232 772.3 6.9 3e-232 772.1 6.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EST45839.1 - 1.8e-15 56.6 0.0 2.4e-14 52.9 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EST45839.1 - 3.7e-05 23.5 0.0 9.2e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 EST45839.1 - 0.008 15.2 0.1 0.092 11.7 0.1 2.2 1 1 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.6 EST45839.1 - 0.019 15.4 0.7 6.2 7.3 0.1 3.1 3 1 0 3 3 3 0 Cell division protein FtsA NRho PF16733.5 EST45839.1 - 0.019 15.0 0.0 0.054 13.6 0.0 1.7 1 0 0 1 1 1 0 Rhomboid N-terminal domain HOIP-UBA PF16678.5 EST45839.1 - 0.074 13.1 0.1 0.34 10.9 0.0 2.0 2 0 0 2 2 2 0 HOIP UBA domain pair PilM_2 PF11104.8 EST45839.1 - 0.091 11.8 0.1 1.1 8.2 0.0 2.1 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; Glu-tRNAGln PF02686.15 EST45839.1 - 6.9 7.0 5.7 1.8 8.9 0.2 2.7 3 0 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit HSP70 PF00012.20 EST45840.1 - 8.4e-50 169.6 0.3 9.2e-50 169.4 0.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EST45840.1 - 0.0017 17.3 0.2 0.0019 17.0 0.2 1.2 1 0 0 1 1 1 1 MreB/Mbl protein VSP PF03302.13 EST45841.1 - 0.0029 16.5 88.3 0.18 10.6 24.5 4.9 1 1 4 5 5 5 3 Giardia variant-specific surface protein PARM PF17061.5 EST45841.1 - 0.015 15.5 1.8 0.023 14.9 1.8 1.3 1 0 0 1 1 1 0 PARM Podoplanin PF05808.11 EST45841.1 - 0.31 11.1 6.7 0.58 10.3 6.7 1.3 1 0 0 1 1 1 0 Podoplanin VSP PF03302.13 EST45842.1 - 0.005 15.7 26.9 0.005 15.7 26.9 2.6 1 1 2 3 3 3 2 Giardia variant-specific surface protein CYYR1 PF10873.8 EST45843.1 - 0.0084 16.6 2.5 0.011 16.2 2.5 1.1 1 0 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 Herpes_gE PF02480.16 EST45843.1 - 0.016 14.0 0.0 0.018 13.8 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Podoplanin PF05808.11 EST45845.1 - 0.0013 18.8 2.2 0.0013 18.8 2.2 1.6 2 0 0 2 2 2 1 Podoplanin TPPK_C PF12555.8 EST45845.1 - 0.0027 17.7 0.3 0.0044 17.0 0.3 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphokinase C terminal Spec3 PF15795.5 EST45846.1 - 0.72 10.4 9.4 5.3 7.6 7.0 2.3 1 1 1 2 2 2 0 Ectodermal ciliogenesis protein VSP PF03302.13 EST45847.1 - 7e-05 21.9 128.3 0.046 12.6 10.4 7.4 1 1 3 5 5 5 5 Giardia variant-specific surface protein Podoplanin PF05808.11 EST45847.1 - 0.00018 21.7 1.6 0.00032 20.8 1.6 1.3 1 0 0 1 1 1 1 Podoplanin CD99L2 PF12301.8 EST45847.1 - 0.091 13.0 0.1 0.15 12.3 0.1 1.3 1 0 0 1 1 1 0 CD99 antigen like protein 2 Syndecan PF01034.20 EST45847.1 - 0.12 12.3 0.6 0.25 11.3 0.6 1.5 1 0 0 1 1 1 0 Syndecan domain TraE PF05309.11 EST45847.1 - 0.23 10.8 0.1 0.35 10.2 0.1 1.1 1 0 0 1 1 1 0 TraE protein DUF5537 PF17690.1 EST45847.1 - 9.9 5.8 7.2 0.67 9.6 1.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5537) Pribosyltran PF00156.27 EST45849.1 - 0.054 13.0 0.0 0.058 12.9 0.0 1.1 1 0 0 1 1 1 0 Phosphoribosyl transferase domain SNF2_N PF00176.23 EST45850.1 - 3.9e-54 183.7 0.0 3.9e-54 183.7 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EST45850.1 - 4.6e-17 62.4 0.0 2.4e-16 60.1 0.0 2.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EST45850.1 - 9.4e-05 22.2 0.0 0.00032 20.5 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase AT_hook PF02178.19 EST45850.1 - 0.58 10.2 1.6 1.5 8.9 1.6 1.7 1 0 0 1 1 1 0 AT hook motif DUF3042 PF11240.8 EST45851.1 - 0.056 13.5 0.6 0.11 12.6 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) Insulin_TMD PF17870.1 EST45851.1 - 0.068 13.3 1.0 0.12 12.5 1.0 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Vps4_C PF09336.10 EST45851.1 - 0.16 12.0 1.2 0.4 10.7 1.2 1.7 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain VSP PF03302.13 EST45851.1 - 0.3 9.9 114.1 2.4 6.9 35.0 5.2 1 1 1 3 3 3 0 Giardia variant-specific surface protein Trs65 PF12735.7 EST45852.1 - 0.11 11.9 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 Spec3 PF15795.5 EST45854.1 - 0.72 10.4 9.4 5.3 7.6 7.0 2.3 1 1 1 2 2 2 0 Ectodermal ciliogenesis protein Podoplanin PF05808.11 EST45855.1 - 0.00016 21.8 2.2 0.00028 21.0 2.2 1.3 1 0 0 1 1 1 1 Podoplanin TPPK_C PF12555.8 EST45855.1 - 0.00066 19.7 0.3 0.001 19.0 0.3 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphokinase C terminal Cytochrom_B561 PF03188.16 EST45855.1 - 0.068 13.3 0.0 0.097 12.8 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 DUF3552 PF12072.8 EST45855.1 - 0.39 10.1 1.0 0.51 9.7 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) CYYR1 PF10873.8 EST45858.1 - 0.013 16.0 2.5 0.017 15.6 2.5 1.1 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Herpes_gE PF02480.16 EST45858.1 - 0.026 13.3 0.0 0.034 12.9 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E VSP PF03302.13 EST45859.1 - 1.4e-05 24.2 18.7 1.6e-05 23.9 18.7 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein VSP PF03302.13 EST45860.1 - 0.0029 16.5 88.3 0.18 10.6 24.5 4.9 1 1 4 5 5 5 3 Giardia variant-specific surface protein PARM PF17061.5 EST45860.1 - 0.015 15.5 1.8 0.023 14.9 1.8 1.3 1 0 0 1 1 1 0 PARM Podoplanin PF05808.11 EST45860.1 - 0.31 11.1 6.7 0.58 10.3 6.7 1.3 1 0 0 1 1 1 0 Podoplanin DUF3135 PF11333.8 EST45861.1 - 0.031 14.5 1.8 0.042 14.1 1.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3135) TMPIT PF07851.13 EST45861.1 - 0.041 13.1 1.0 0.044 13.0 1.0 1.0 1 0 0 1 1 1 0 TMPIT-like protein HR1 PF02185.16 EST45861.1 - 0.053 13.6 2.9 0.068 13.3 2.9 1.1 1 0 0 1 1 1 0 Hr1 repeat Cyclin_N PF00134.23 EST45863.1 - 1.7e-07 31.0 0.3 2.2e-07 30.7 0.3 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Promethin PF16015.5 EST45865.1 - 0.0028 17.6 0.4 0.0033 17.3 0.4 1.1 1 0 0 1 1 1 1 Promethin Diphthamide_syn PF01866.17 EST45867.1 - 0.1 12.0 0.2 1.5 8.2 0.0 1.9 1 1 1 2 2 2 0 Putative diphthamide synthesis protein Thioredoxin PF00085.20 EST45868.1 - 8.5e-08 32.1 0.0 9.5e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AAA_lid_10 PF17872.1 EST45869.1 - 0.29 11.3 5.9 0.33 11.1 0.0 3.2 3 1 1 4 4 4 0 AAA lid domain Orf78 PF06024.12 EST45870.1 - 0.0059 16.9 0.0 0.0063 16.8 0.0 1.1 1 0 0 1 1 1 1 Orf78 (ac78) YfhO PF09586.10 EST45870.1 - 0.016 13.4 0.1 0.017 13.4 0.1 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO 7tm_3 PF00003.22 EST45870.1 - 0.032 14.0 0.1 0.036 13.8 0.1 1.0 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR DUF2684 PF10885.8 EST45870.1 - 0.062 13.4 0.1 0.083 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2684) LMWPc PF01451.21 EST45871.1 - 0.17 12.3 1.6 3.8 7.9 0.3 2.2 1 1 1 2 2 2 0 Low molecular weight phosphotyrosine protein phosphatase FlaC_arch PF05377.11 EST45871.1 - 1.4 9.4 4.9 0.78 10.2 0.4 2.5 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) IFP_35_N PF07334.13 EST45871.1 - 4.3 7.5 7.3 0.71 10.0 1.4 2.6 2 1 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Myb_DNA-bind_6 PF13921.6 EST45872.1 - 2.3e-06 27.7 0.2 3e-06 27.4 0.2 1.3 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EST45872.1 - 0.00042 20.4 0.0 0.00067 19.8 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST45872.1 - 0.00059 19.7 0.8 0.0008 19.3 0.8 1.2 1 0 0 1 1 1 1 Myb DNA-binding like GCR1_C PF12550.8 EST45872.1 - 0.19 12.1 4.2 0.51 10.7 4.2 1.7 1 1 0 1 1 1 0 Transcriptional activator of glycolytic enzymes Ank_2 PF12796.7 EST45873.1 - 4.3e-32 110.6 2.1 5.3e-15 55.8 0.1 2.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EST45873.1 - 3.1e-12 46.8 0.0 5.6e-08 33.2 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EST45873.1 - 5.1e-12 44.9 0.0 0.00053 20.2 0.0 4.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 EST45873.1 - 4.1e-11 42.9 0.0 1.2e-06 28.6 0.0 3.7 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EST45873.1 - 6.7e-08 32.6 0.0 0.0021 18.4 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat DUF1815 PF08844.10 EST45873.1 - 0.11 12.4 0.1 1.3 9.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1815) zf-C3HC4_3 PF13920.6 EST45874.1 - 0.089 12.7 1.5 0.19 11.6 1.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Cation_ATPase_C PF00689.21 EST45875.1 - 1.4e-44 152.0 4.5 1.4e-44 152.0 4.5 3.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EST45875.1 - 4.9e-36 123.9 3.0 4.9e-36 123.9 3.0 3.3 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EST45875.1 - 7.2e-17 62.4 0.0 1.9e-08 34.8 0.0 3.2 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EST45875.1 - 3.9e-14 52.5 0.0 8.1e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EST45875.1 - 9.8e-14 50.8 0.3 2.2e-13 49.7 0.3 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EST45875.1 - 5.3e-06 26.4 2.5 2.8e-05 24.0 0.8 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Clathrin PF00637.20 EST45876.1 - 5.2e-65 217.7 25.3 3.5e-17 62.6 0.1 9.2 8 1 1 9 9 9 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 EST45876.1 - 4e-18 65.1 0.3 5.9e-17 61.3 0.0 3.1 3 0 0 3 3 3 1 Clathrin-H-link ANAPC3 PF12895.7 EST45876.1 - 0.054 13.7 1.5 10 6.4 0.0 4.4 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 EST45876.1 - 0.13 12.2 0.1 1.7 8.6 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Pribosyltran PF00156.27 EST45877.1 - 1.4e-09 37.6 0.0 2.1e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain AAA_14 PF13173.6 EST45877.1 - 0.056 13.5 0.0 11 6.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Fijivirus_P9-2 PF06837.11 EST45878.1 - 0.0095 15.4 0.1 0.0097 15.4 0.1 1.1 1 0 0 1 1 1 1 Fijivirus P9-2 protein Amastin PF07344.11 EST45878.1 - 0.019 14.8 2.6 0.021 14.7 2.6 1.1 1 0 0 1 1 1 0 Amastin surface glycoprotein YlaC PF10777.9 EST45878.1 - 0.02 14.7 0.4 0.021 14.7 0.4 1.1 1 0 0 1 1 1 0 Inner membrane protein YlaC DUF4131 PF13567.6 EST45878.1 - 0.022 14.4 0.1 0.024 14.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Tetraspanin PF00335.20 EST45878.1 - 0.041 13.6 0.8 0.039 13.7 0.8 1.0 1 0 0 1 1 1 0 Tetraspanin family DUF5534 PF17686.1 EST45878.1 - 0.042 14.1 0.1 0.044 14.0 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5534) SUR7 PF06687.12 EST45878.1 - 0.054 13.1 2.7 0.065 12.9 2.7 1.1 1 0 0 1 1 1 0 SUR7/PalI family DUF2244 PF10003.9 EST45878.1 - 0.19 11.4 1.9 0.25 11.0 1.9 1.1 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) DUF2207 PF09972.9 EST45878.1 - 0.38 9.5 1.3 0.4 9.4 1.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SPC12 PF06645.13 EST45878.1 - 0.53 10.4 3.1 0.71 10.0 3.1 1.2 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Lipase_GDSL_2 PF13472.6 EST45879.1 - 6.9e-16 59.2 0.0 8e-16 58.9 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EST45879.1 - 1.3e-06 28.5 0.0 1.6e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ALGX PF16822.5 EST45879.1 - 0.059 13.0 0.2 0.88 9.2 0.0 2.1 2 0 0 2 2 2 0 SGNH hydrolase-like domain, acetyltransferase AlgX DnaJ PF00226.31 EST45881.1 - 3.6e-18 65.4 0.3 1.4e-17 63.6 0.3 2.1 1 0 0 1 1 1 1 DnaJ domain DUF2802 PF10975.8 EST45881.1 - 0.037 14.1 0.3 1 9.5 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) Atg14 PF10186.9 EST45883.1 - 0.0022 17.2 7.4 0.0029 16.8 7.4 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 ATG16 PF08614.11 EST45883.1 - 0.008 16.4 9.6 0.011 16.0 9.6 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) NUP214 PF16755.5 EST45883.1 - 0.015 14.6 3.9 0.019 14.2 3.9 1.1 1 0 0 1 1 1 0 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 CCDC144C PF14915.6 EST45883.1 - 0.023 13.8 9.9 0.03 13.4 9.9 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Spindle_Spc25 PF08234.12 EST45883.1 - 0.062 13.5 0.1 0.22 11.8 0.1 2.0 1 1 0 1 1 1 0 Chromosome segregation protein Spc25 DUF3896 PF13035.6 EST45883.1 - 0.2 11.9 2.9 0.54 10.5 1.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3896) CENP-F_leu_zip PF10473.9 EST45883.1 - 0.4 10.7 10.3 0.59 10.2 10.3 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mod_r PF07200.13 EST45883.1 - 1.4 9.0 16.0 0.1 12.7 8.3 2.4 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein zf-C3HC4_3 PF13920.6 EST45884.1 - 4.9e-09 35.9 38.6 3.4e-05 23.6 7.2 3.8 3 0 0 3 3 3 3 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EST45884.1 - 1.4e-05 24.8 11.7 1.4e-05 24.8 11.7 4.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EST45884.1 - 3.6e-05 23.5 10.9 3.6e-05 23.5 10.9 3.8 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EST45884.1 - 5.9e-05 23.1 12.3 5.9e-05 23.1 12.3 4.2 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EST45884.1 - 0.00033 20.6 11.1 0.00033 20.6 11.1 3.5 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 EST45884.1 - 0.0012 19.1 10.8 0.0012 19.1 10.8 3.9 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 EST45884.1 - 0.0023 17.8 10.1 0.0023 17.8 10.1 4.1 4 0 0 4 4 4 1 zinc-RING finger domain DYW_deaminase PF14432.6 EST45885.1 - 0.004 17.0 0.3 0.0083 16.0 0.3 1.5 1 1 0 1 1 1 1 DYW family of nucleic acid deaminases PCRF PF03462.18 EST45885.1 - 0.074 12.9 0.1 0.095 12.6 0.1 1.2 1 0 0 1 1 1 0 PCRF domain CENP-F_leu_zip PF10473.9 EST45885.1 - 0.14 12.1 2.5 0.088 12.8 0.9 1.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Glucosamine_iso PF01182.20 EST45891.1 - 6.6e-14 52.3 0.0 9.2e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Ribosomal_L6 PF00347.23 EST45892.1 - 3.5e-18 66.0 0.7 9.7e-12 45.4 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Peptidase_S30 PF01577.16 EST45892.1 - 0.084 12.5 1.9 19 4.7 0.1 2.9 2 1 1 3 3 3 0 Potyvirus P1 protease VSP PF03302.13 EST45896.1 - 8.3e-07 28.2 187.3 0.031 13.1 24.3 7.7 1 1 7 8 8 8 6 Giardia variant-specific surface protein Podoplanin PF05808.11 EST45896.1 - 0.04 14.0 0.1 0.073 13.2 0.1 1.3 1 0 0 1 1 1 0 Podoplanin Tad PF13400.6 EST45896.1 - 0.53 10.6 3.0 0.85 10.0 3.0 1.2 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like Chordopox_A15 PF05846.12 EST45898.1 - 0.038 14.2 0.0 0.11 12.7 0.0 1.7 2 0 0 2 2 2 0 Chordopoxvirus A15 protein fn3_4 PF16794.5 EST45901.1 - 0.087 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Fibronectin-III type domain ANAPC3 PF12895.7 EST45905.1 - 0.014 15.6 6.1 0.058 13.6 0.1 2.4 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Flavodoxin_1 PF00258.25 EST45907.1 - 5.7e-19 68.7 0.0 6.6e-19 68.5 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 EST45907.1 - 7.7e-05 23.0 0.0 0.0001 22.6 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_NdrI PF07972.11 EST45907.1 - 0.0002 21.5 0.1 0.00024 21.3 0.1 1.1 1 0 0 1 1 1 1 NrdI Flavodoxin like Flavodoxin_3 PF12641.7 EST45907.1 - 0.0035 17.1 0.3 0.0084 15.8 0.3 1.8 1 1 0 1 1 1 1 Flavodoxin domain ANAPC4_WD40 PF12894.7 EST45908.1 - 5.2e-09 36.3 0.1 0.0092 16.3 0.0 5.6 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EST45908.1 - 4.1e-08 33.8 2.2 0.033 15.1 0.0 5.0 4 0 0 4 4 4 2 WD domain, G-beta repeat Clathrin PF00637.20 EST45908.1 - 0.0005 20.0 23.8 3.4 7.5 2.1 7.1 5 2 2 7 7 7 3 Region in Clathrin and VPS Ge1_WD40 PF16529.5 EST45908.1 - 0.0048 15.9 0.2 2.6 6.9 0.0 2.6 1 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Leuk-A4-hydro_C PF09127.11 EST45908.1 - 0.023 14.7 0.2 0.15 12.2 0.2 2.4 1 0 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal TPR_19 PF14559.6 EST45908.1 - 0.032 14.7 0.2 0.032 14.7 0.2 5.7 5 1 0 5 5 5 0 Tetratricopeptide repeat PD40 PF07676.12 EST45908.1 - 0.22 11.5 0.5 9 6.4 0.1 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat TPR_1 PF00515.28 EST45908.1 - 0.26 11.2 0.0 0.26 11.2 0.0 7.8 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_11 PF13414.6 EST45908.1 - 0.58 9.9 3.9 45 3.9 0.0 4.5 5 0 0 5 5 5 0 TPR repeat Porphyrn_cat_1 PF18206.1 EST45908.1 - 0.95 10.1 4.0 4.6 7.9 1.1 3.6 3 1 1 4 4 4 0 Porphyranase catalytic subdomain 1 PPR PF01535.20 EST45908.1 - 1.1 9.7 3.1 52 4.4 0.1 4.9 7 0 0 7 7 4 0 PPR repeat TPR_16 PF13432.6 EST45908.1 - 7.1 7.4 20.1 4 8.2 0.4 6.1 5 1 1 6 6 6 0 Tetratricopeptide repeat RRM_1 PF00076.22 EST45909.1 - 7.7e-05 22.4 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EST45909.1 - 0.11 12.0 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) THP2 PF09432.10 EST45910.1 - 0.13 12.4 4.8 0.14 12.2 1.2 2.3 1 1 1 2 2 2 0 Tho complex subunit THP2 Tup_N PF08581.10 EST45910.1 - 3 8.2 10.7 4.7 7.6 0.7 3.6 4 0 0 4 4 4 0 Tup N-terminal UCH PF00443.29 EST45912.1 - 3.6e-35 121.7 0.0 5.9e-35 121.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 EST45912.1 - 4.8e-06 26.2 0.0 5.8e-05 22.8 0.1 2.7 3 0 0 3 3 3 1 Ubiquitin family UCH_1 PF13423.6 EST45912.1 - 3.1e-05 23.7 0.0 0.00077 19.1 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase YukD PF08817.10 EST45912.1 - 0.011 16.4 0.0 0.046 14.4 0.0 2.1 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD LRR_8 PF13855.6 EST45913.1 - 4.5e-05 23.1 19.5 0.019 14.7 1.1 3.9 3 0 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EST45913.1 - 0.002 18.5 31.0 0.034 14.6 0.5 5.5 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EST45913.1 - 0.079 13.1 9.3 1.5 9.1 0.8 5.0 5 0 0 5 5 5 0 Leucine Rich repeat GED PF02212.18 EST45913.1 - 0.46 10.7 0.0 0.46 10.7 0.0 3.6 5 0 0 5 5 5 0 Dynamin GTPase effector domain LRR_9 PF14580.6 EST45913.1 - 0.56 9.7 12.4 0.016 14.7 4.3 2.5 2 1 0 2 2 2 0 Leucine-rich repeat Ephrin_rec_like PF07699.13 EST45914.1 - 2.1e-15 56.2 18.5 1.6e-08 34.2 0.4 4.4 3 1 1 4 4 4 3 Putative ephrin-receptor like NCD3G PF07562.14 EST45914.1 - 0.068 13.1 21.2 0.13 12.3 1.3 3.6 2 1 1 4 4 4 0 Nine Cysteines Domain of family 3 GPCR DNA_topoisoIV PF00521.20 EST45915.1 - 2.5e-99 333.0 3.2 5.3e-99 332.0 3.2 1.6 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 EST45915.1 - 3.6e-34 117.8 5.1 3.6e-34 117.8 5.1 2.9 2 1 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 EST45915.1 - 2.9e-18 66.0 0.3 1.7e-17 63.5 0.3 2.3 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.22 EST45915.1 - 8.8e-08 32.3 0.0 4.6e-07 30.0 0.0 2.3 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.26 EST45915.1 - 0.00016 22.2 0.0 0.00036 21.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FtsH_ext PF06480.15 EST45917.1 - 0.0036 17.6 0.0 0.0038 17.6 0.0 1.3 1 0 0 1 1 1 1 FtsH Extracellular CENP-X PF09415.10 EST45917.1 - 0.091 13.1 1.1 2.4 8.5 0.5 2.2 2 0 0 2 2 2 0 CENP-S associating Centromere protein X DUF3984 PF13136.6 EST45918.1 - 0.0014 18.1 2.4 0.0015 18.0 2.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3984) Tam41_Mmp37 PF09139.11 EST45918.1 - 0.081 12.4 1.8 0.09 12.2 1.8 1.0 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial KASH_CCD PF14662.6 EST45919.1 - 0.0011 18.8 24.4 0.0011 18.8 24.4 3.2 1 1 2 3 3 3 1 Coiled-coil region of CCDC155 or KASH DUF667 PF05018.13 EST45920.1 - 2.8e-34 118.5 0.0 4.7e-34 117.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Ank_2 PF12796.7 EST45921.1 - 4.1e-31 107.4 2.4 1.8e-09 38.0 0.0 4.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EST45921.1 - 3e-19 69.1 1.9 0.00049 20.6 0.1 6.5 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EST45921.1 - 2.1e-16 58.3 0.5 0.001 19.4 0.0 6.8 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 EST45921.1 - 3.6e-14 52.6 0.9 0.061 13.7 0.1 6.9 3 2 4 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 EST45921.1 - 6.6e-13 48.5 2.3 0.033 14.6 0.0 7.2 8 0 0 8 8 8 3 Ankyrin repeat DUF4485 PF14846.6 EST45922.1 - 5.5e-14 52.0 0.7 1.4e-13 50.6 0.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4485) MCRS_N PF13325.6 EST45922.1 - 0.0011 19.0 5.6 0.97 9.4 4.2 2.4 2 1 0 2 2 2 2 N-terminal region of micro-spherule protein PKcGMP_CC PF16808.5 EST45922.1 - 0.0057 16.5 0.6 0.3 11.0 1.4 2.6 2 0 0 2 2 2 1 Coiled-coil N-terminus of cGMP-dependent protein kinase STT3_PglB_C PF18527.1 EST45922.1 - 0.024 14.7 1.0 0.024 14.7 1.0 1.7 2 0 0 2 2 2 0 STT3/PglB C-terminal beta-barrel domain DUF641 PF04859.12 EST45922.1 - 0.29 11.5 5.4 0.24 11.7 2.3 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) ANAPC4_WD40 PF12894.7 EST45924.1 - 3.6e-05 24.0 0.2 0.036 14.4 0.0 5.2 7 0 0 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_7 PF13499.6 EST45924.1 - 0.0043 17.5 0.1 0.029 14.8 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EST45924.1 - 0.022 14.7 0.4 0.3 11.1 0.1 2.9 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 EST45924.1 - 0.024 14.2 0.2 0.11 12.1 0.2 2.3 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.6 EST45924.1 - 0.13 12.1 0.1 0.43 10.5 0.1 1.9 1 0 0 1 1 1 0 EF-hand domain pair UPF0262 PF06793.12 EST45924.1 - 0.21 11.7 2.3 5.2 7.1 0.1 3.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0262) 5_nucleotid_C PF02872.18 EST45928.1 - 3.5e-05 24.1 0.0 5.3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Pkinase PF00069.25 EST45929.1 - 2.3e-47 161.6 0.0 4.4e-47 160.7 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST45929.1 - 3.2e-23 82.3 0.0 1e-22 80.7 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 EST45929.1 - 2.5e-08 33.8 0.1 4.3e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EST45929.1 - 2.2e-06 27.8 0.0 0.0025 17.8 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EST45929.1 - 3.3e-06 26.6 0.1 7.5e-06 25.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EST45929.1 - 0.00024 20.5 0.2 0.0005 19.5 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EST45929.1 - 0.026 13.3 0.0 0.035 12.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 EST45929.1 - 0.1 11.6 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 PIP49_C PF12260.8 EST45929.1 - 0.12 12.0 0.1 0.25 10.9 0.1 1.6 1 1 0 1 1 1 0 Protein-kinase domain of FAM69 Glyco_transf_41 PF13844.6 EST45930.1 - 0.025 13.0 0.4 0.025 13.0 0.4 2.5 1 1 2 3 3 3 0 Glycosyl transferase family 41 Peptidase_C97 PF05903.14 EST45932.1 - 8.8e-18 64.6 0.3 2.2e-17 63.3 0.3 1.6 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF778 PF05608.12 EST45932.1 - 0.68 10.3 8.2 8.7 6.7 8.2 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF778) Aldose_epim PF01263.20 EST45933.1 - 1e-17 64.4 0.1 2.3e-17 63.3 0.1 1.6 1 1 0 1 1 1 1 Aldose 1-epimerase L27_1 PF09058.10 EST45933.1 - 0.15 12.1 0.1 0.8 9.7 0.0 2.1 2 0 0 2 2 2 0 L27_1 IMS PF00817.20 EST45934.1 - 0.0041 17.1 0.5 0.24 11.4 0.1 3.1 3 0 0 3 3 3 1 impB/mucB/samB family bZIP_1 PF00170.21 EST45935.1 - 0.022 14.8 3.6 0.022 14.8 3.6 6.3 4 2 4 8 8 8 0 bZIP transcription factor Fer4 PF00037.27 EST45936.1 - 8.8e-11 41.2 17.0 3.1e-07 29.9 4.3 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EST45936.1 - 1.5e-07 31.9 9.5 2.9e-05 24.5 0.5 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EST45936.1 - 1.6e-07 31.3 13.9 2.6e-07 30.7 13.9 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 EST45936.1 - 4e-07 29.8 16.2 2.1e-06 27.5 3.0 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 EST45936.1 - 7.8e-07 29.1 13.3 1.4e-06 28.3 13.3 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 EST45936.1 - 3.3e-06 26.9 14.5 7.6e-05 22.6 2.2 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 EST45936.1 - 7.9e-06 25.9 17.7 5.8e-05 23.1 3.9 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 EST45936.1 - 2.8e-05 25.0 10.5 0.012 16.5 0.7 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_8 PF13183.6 EST45936.1 - 0.0012 19.2 10.7 0.0069 16.8 1.0 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_22 PF17179.4 EST45936.1 - 0.0013 19.6 8.9 0.016 16.0 0.9 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 EST45936.1 - 0.0057 17.5 21.8 0.0071 17.2 4.5 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_17 PF13534.6 EST45936.1 - 0.0066 17.0 15.4 0.023 15.2 3.2 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 EST45936.1 - 0.015 15.7 15.9 0.028 14.9 3.9 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_15 PF13459.6 EST45936.1 - 0.016 16.0 2.2 0.016 16.0 2.2 2.3 1 1 1 2 2 2 0 4Fe-4S single cluster domain LepB_GAP_C PF18227.1 EST45936.1 - 0.031 14.8 0.1 0.11 13.0 0.0 1.9 2 0 0 2 2 2 0 LepB GAP domain C-terminal subdomain Fer4_18 PF13746.6 EST45936.1 - 0.52 10.5 16.2 3.7 7.8 16.1 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain TrmO PF01980.16 EST45937.1 - 1.8e-13 50.7 0.1 3e-12 46.8 0.0 2.5 3 0 0 3 3 3 1 tRNA-methyltransferase O AvrB_AvrC PF05394.11 EST45937.1 - 0.096 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Avirulence protein RIO1 PF01163.22 EST45939.1 - 1.3e-48 165.1 0.4 1.3e-48 165.1 0.4 2.2 3 0 0 3 3 3 1 RIO1 family Pkinase_fungal PF17667.1 EST45939.1 - 0.0023 16.8 1.3 0.0023 16.8 1.3 2.1 2 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EST45939.1 - 0.015 15.2 0.0 0.034 14.1 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 EST45939.1 - 0.11 12.1 0.1 0.11 12.1 0.1 2.7 2 2 1 3 3 3 0 Choline/ethanolamine kinase PsiE PF06146.12 EST45942.1 - 5.2e-09 36.3 2.5 5.2e-09 36.3 2.5 1.9 2 1 0 2 2 2 1 Phosphate-starvation-inducible E LAB_N PF07578.11 EST45942.1 - 0.063 13.4 1.0 0.14 12.2 1.0 1.6 1 1 0 1 1 1 0 Lipid A Biosynthesis N-terminal domain FtsL PF04999.13 EST45942.1 - 0.084 12.9 2.8 0.69 10.0 0.9 2.6 2 0 0 2 2 2 0 Cell division protein FtsL DHHC PF01529.20 EST45944.1 - 2.5e-16 60.0 21.3 2.5e-16 60.0 21.3 3.0 2 1 0 2 2 2 1 DHHC palmitoyltransferase Zf_RING PF16744.5 EST45944.1 - 0.071 13.2 5.2 0.12 12.5 5.2 1.3 1 0 0 1 1 1 0 KIAA1045 RING finger HRG PF16954.5 EST45944.1 - 0.097 13.1 0.1 0.097 13.1 0.1 3.1 2 1 1 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene AlbA_2 PF04326.14 EST45945.1 - 9.6e-06 25.9 0.1 9.6e-06 25.9 0.1 3.2 3 1 1 4 4 4 1 Putative DNA-binding domain AAA_22 PF13401.6 EST45945.1 - 0.00074 19.8 0.0 0.0026 18.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EST45945.1 - 0.0034 17.4 1.6 0.0034 17.4 1.6 3.6 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.6 EST45945.1 - 0.02 15.3 0.0 0.059 13.7 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 EST45945.1 - 0.057 14.0 0.2 1.7 9.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EST45945.1 - 0.096 12.7 0.0 1 9.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) UEV PF05743.13 EST45946.1 - 1.1e-11 44.6 0.3 3e-11 43.3 0.3 1.8 1 0 0 1 1 1 1 UEV domain CLPTM1 PF05602.12 EST45946.1 - 0.02 14.0 9.6 0.029 13.4 9.6 1.2 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) C4 PF01413.19 EST45946.1 - 0.031 14.7 1.2 0.05 14.0 0.2 1.9 2 0 0 2 2 2 0 C-terminal tandem repeated domain in type 4 procollagen RGI1 PF10843.8 EST45946.1 - 1.1 8.9 5.8 0.2 11.3 0.3 2.4 3 1 1 4 4 4 0 Respiratory growth induced protein 1 EF-hand_7 PF13499.6 EST45947.1 - 0.00051 20.4 1.7 0.32 11.5 0.0 3.5 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EST45947.1 - 0.0033 16.9 0.6 1.3 8.7 0.0 3.9 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 EST45947.1 - 0.0034 17.2 3.6 3.2 7.9 0.0 4.6 5 0 0 5 5 5 2 EF-hand domain HrpF PF06266.12 EST45947.1 - 1.4 9.2 4.3 2 8.7 0.5 2.4 2 0 0 2 2 2 0 HrpF protein mRNA_cap_enzyme PF01331.19 EST45949.1 - 1.1e-21 77.6 0.2 2.4e-20 73.2 0.2 2.9 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 EST45949.1 - 1.7e-07 31.8 0.2 3.3e-07 30.9 0.2 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 EST45949.1 - 6.6e-07 29.2 0.0 3e-06 27.0 0.0 2.0 1 1 0 1 1 1 1 ATP dependent DNA ligase domain Fumerase_C PF05683.12 EST45950.1 - 0.012 14.9 0.3 0.019 14.3 0.3 1.3 1 0 0 1 1 1 0 Fumarase C-terminus Orthopox_F6 PF06601.12 EST45950.1 - 0.086 13.0 3.4 5 7.4 0.5 3.0 3 0 0 3 3 3 0 Orthopoxvirus F6 protein DivIC PF04977.15 EST45950.1 - 0.45 10.3 13.1 1.4 8.7 1.8 3.5 2 1 1 3 3 3 0 Septum formation initiator bZIP_2 PF07716.15 EST45950.1 - 5.5 7.1 6.3 1.6 8.9 0.5 2.7 2 1 0 2 2 2 0 Basic region leucine zipper SET PF00856.28 EST45951.1 - 2e-13 51.1 0.2 1.2e-12 48.5 0.2 2.2 1 1 0 1 1 1 1 SET domain LAGLIDADG_WhiA PF14527.6 EST45951.1 - 0.069 13.2 0.5 0.34 11.0 0.5 2.2 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain L27_N PF09060.10 EST45951.1 - 0.074 13.1 5.2 0.15 12.1 1.4 3.0 2 0 0 2 2 2 0 L27_N Vac_Fusion PF02346.16 EST45952.1 - 0.18 11.5 1.1 2.1 8.1 1.1 2.4 1 1 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 FliD_N PF02465.18 EST45953.1 - 0.28 11.9 0.1 0.28 11.9 0.1 2.3 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus PP2C PF00481.21 EST45954.1 - 4.1e-39 134.8 0.1 2e-37 129.2 0.1 2.8 1 1 0 1 1 1 1 Protein phosphatase 2C Pyr_redox_2 PF07992.14 EST45955.1 - 3.7e-54 183.9 0.4 5.2e-54 183.5 0.4 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EST45955.1 - 7e-18 65.0 3.0 4.2e-15 56.1 0.2 3.8 4 0 0 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EST45955.1 - 2.3e-09 37.5 0.1 9.2e-09 35.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_3 PF13738.6 EST45955.1 - 3.2e-09 36.5 1.0 6.5e-06 25.6 0.2 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EST45955.1 - 1.7e-07 31.1 0.6 0.17 11.4 0.0 4.0 4 0 0 4 4 4 2 FAD dependent oxidoreductase HI0933_like PF03486.14 EST45955.1 - 1.4e-06 27.3 1.2 0.24 10.1 0.0 4.0 3 1 1 4 4 4 3 HI0933-like protein K_oxygenase PF13434.6 EST45955.1 - 3.3e-06 26.5 0.0 2.1e-05 23.9 0.0 2.2 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EST45955.1 - 7.9e-06 25.9 0.6 0.13 12.2 0.0 4.1 3 1 1 4 4 4 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 EST45955.1 - 8.7e-05 22.0 0.1 0.0039 16.5 0.0 2.2 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EST45955.1 - 0.0012 19.0 0.2 2 8.7 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 EST45955.1 - 0.0038 17.6 0.1 0.23 11.9 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding 3HCDH_N PF02737.18 EST45955.1 - 0.013 15.4 0.0 0.042 13.7 0.0 1.9 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EST45955.1 - 0.017 14.7 4.3 0.049 13.2 0.5 3.3 3 1 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.22 EST45955.1 - 0.034 13.2 6.9 0.12 11.4 1.1 3.0 1 1 3 4 4 4 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EST45955.1 - 0.06 12.4 0.0 3.4 6.6 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein TrkA_N PF02254.18 EST45955.1 - 0.076 13.3 0.3 11 6.3 0.1 2.6 2 0 0 2 2 2 0 TrkA-N domain F420_oxidored PF03807.17 EST45955.1 - 2.7 8.6 5.6 8.5 7.0 0.2 3.9 4 1 1 5 5 4 0 NADP oxidoreductase coenzyme F420-dependent zf-C2HE PF16278.5 EST45956.1 - 0.051 14.0 0.1 0.26 11.7 0.0 2.2 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Pkinase PF00069.25 EST45958.1 - 3.3e-27 95.5 0.1 2e-21 76.6 0.1 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EST45958.1 - 6.3e-09 35.5 0.0 2.5e-08 33.5 0.0 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EST45958.1 - 0.00017 21.0 0.0 0.0097 15.2 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EST45958.1 - 0.011 15.1 0.2 0.031 13.6 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Proteasome PF00227.26 EST45959.1 - 5.7e-37 127.1 0.1 7.2e-37 126.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EST45959.1 - 1.2e-05 24.9 1.0 2.1e-05 24.1 1.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature EF-hand_14 PF17959.1 EST45961.1 - 0.086 13.2 0.1 0.086 13.2 0.1 3.2 3 1 1 4 4 4 0 EF-hand domain MOZ_SAS PF01853.18 EST45962.1 - 3.3e-52 176.7 2.9 5.5e-52 176.0 2.9 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EST45962.1 - 5.7e-17 61.1 6.7 1.2e-16 60.0 6.7 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 EST45962.1 - 0.0093 16.4 0.0 0.029 14.8 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EST45962.1 - 0.017 15.1 0.0 0.048 13.6 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Cytomega_UL84 PF06284.11 EST45962.1 - 0.2 10.1 0.1 0.28 9.6 0.1 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DUF2028 PF09667.10 EST45964.1 - 0.045 13.7 0.2 0.091 12.7 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2028) Mntp PF02659.15 EST45964.1 - 0.15 11.8 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative manganese efflux pump Kinesin PF00225.23 EST45968.1 - 7.4e-63 212.5 6.4 7.4e-63 212.5 6.4 2.2 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EST45968.1 - 3.6e-17 62.7 0.2 3.6e-17 62.7 0.2 2.8 3 1 0 3 3 3 1 Microtubule binding DUF1465 PF07323.12 EST45968.1 - 0.018 14.9 1.3 0.51 10.2 1.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) Costars PF14705.6 EST45968.1 - 0.074 13.2 0.7 0.3 11.3 0.2 2.3 2 0 0 2 2 2 0 Costars Sua5_yciO_yrdC PF01300.18 EST45969.1 - 3.9e-45 153.5 0.0 5.4e-45 153.1 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 EST45969.1 - 4e-06 27.4 0.0 6.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding TPR_12 PF13424.6 EST45970.1 - 0.0043 17.3 0.3 0.021 15.1 0.1 2.3 2 1 0 2 2 2 1 Tetratricopeptide repeat DUF2408 PF10303.9 EST45970.1 - 0.0063 17.1 4.4 0.35 11.4 0.8 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF2408) DUF3802 PF12290.8 EST45970.1 - 0.015 15.8 1.2 0.042 14.4 1.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3802) TPR_8 PF13181.6 EST45970.1 - 0.12 12.6 2.5 18 5.9 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EST45970.1 - 0.16 12.2 2.2 0.31 11.3 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EST45970.1 - 0.31 10.9 4.4 0.46 10.4 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat PHM7_cyt PF14703.6 EST45971.1 - 2.3e-09 37.7 1.1 4e-09 36.9 1.1 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Anoctamin PF04547.12 EST45971.1 - 1.1e-05 24.5 19.7 1.1e-05 24.5 19.7 1.7 2 0 0 2 2 2 1 Calcium-activated chloride channel Arf PF00025.21 EST45972.1 - 3.7e-62 208.8 0.0 4.3e-62 208.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EST45972.1 - 2.2e-16 60.1 0.0 3.2e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EST45972.1 - 2e-13 50.3 0.0 2.2e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EST45972.1 - 2.1e-11 43.6 0.0 2.8e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EST45972.1 - 2.2e-09 37.0 0.0 2.6e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EST45972.1 - 1.7e-08 34.1 0.1 3.8e-06 26.3 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 EST45972.1 - 1e-07 32.0 0.0 2e-07 31.1 0.0 1.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase NTPase_1 PF03266.15 EST45972.1 - 0.0011 18.8 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 NTPase 6PF2K PF01591.18 EST45972.1 - 0.0023 17.3 0.0 0.0043 16.4 0.0 1.7 1 1 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.6 EST45972.1 - 0.0035 17.5 0.1 0.0052 16.9 0.1 1.5 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 EST45972.1 - 0.0054 16.3 0.2 0.088 12.3 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 EST45972.1 - 0.0087 15.1 0.1 0.15 11.0 0.0 2.2 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 EST45972.1 - 0.011 16.1 0.0 0.017 15.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 EST45972.1 - 0.012 15.2 0.1 0.041 13.5 0.1 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain TIR_2 PF13676.6 EST45972.1 - 0.019 15.6 0.0 0.027 15.1 0.0 1.3 1 0 0 1 1 1 0 TIR domain PAS_4 PF08448.10 EST45972.1 - 0.03 14.6 0.0 2.5 8.4 0.0 2.2 1 1 1 2 2 2 0 PAS fold RsgA_GTPase PF03193.16 EST45972.1 - 0.047 13.6 0.0 5.4 6.9 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_14 PF13173.6 EST45972.1 - 0.047 13.7 0.1 0.83 9.7 0.0 2.0 1 1 1 2 2 2 0 AAA domain TsaE PF02367.17 EST45972.1 - 0.095 12.7 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Thioredoxin_2 PF13098.6 EST45972.1 - 0.15 12.6 0.0 0.48 10.9 0.0 1.8 1 1 1 2 2 2 0 Thioredoxin-like domain AAA_28 PF13521.6 EST45972.1 - 0.17 12.1 0.1 0.41 10.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain PDEase_I PF00233.19 EST45973.1 - 4.3e-45 154.3 3.0 5.3e-45 154.0 0.3 2.5 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Band_7 PF01145.25 EST45973.1 - 0.095 12.7 1.7 0.22 11.5 1.7 1.6 1 0 0 1 1 1 0 SPFH domain / Band 7 family Carbpep_Y_N PF05388.11 EST45974.1 - 0.0004 20.9 3.1 0.0007 20.1 0.3 2.1 2 1 0 2 2 2 1 Carboxypeptidase Y pro-peptide Peptidase_M14 PF00246.24 EST45976.1 - 3.3e-18 66.5 0.0 7.5e-18 65.3 0.0 1.8 1 1 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 EST45976.1 - 6.9e-10 39.2 0.7 1.3e-09 38.4 0.7 1.4 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain AstE_AspA PF04952.14 EST45976.1 - 0.005 15.9 0.1 0.077 12.1 0.0 2.2 2 0 0 2 2 2 1 Succinylglutamate desuccinylase / Aspartoacylase family DUF2817 PF10994.8 EST45976.1 - 0.024 14.1 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) Lebercilin PF15619.6 EST45977.1 - 0.00024 20.8 23.3 0.00024 20.8 23.3 2.3 1 1 1 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease DUF3584 PF12128.8 EST45977.1 - 0.0035 15.0 24.7 0.0039 14.8 24.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Pox_A_type_inc PF04508.12 EST45977.1 - 0.012 15.4 1.8 0.097 12.6 0.8 2.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF1818 PF08848.11 EST45977.1 - 1 9.4 8.9 0.21 11.7 1.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1818) DUF1664 PF07889.12 EST45977.1 - 1.1 9.3 15.2 0.72 9.9 3.9 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2570 PF10828.8 EST45977.1 - 1.2 8.9 30.4 0.31 10.9 9.1 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF2570) Zein-binding PF04576.15 EST45977.1 - 3.8 7.9 20.9 0.047 14.0 3.6 2.8 1 1 1 2 2 2 0 Zein-binding Syja_N PF02383.18 EST45978.1 - 0.029 13.7 1.0 0.13 11.5 0.9 2.1 1 1 0 1 1 1 0 SacI homology domain V-SNARE PF05008.15 EST45979.1 - 0.00027 21.3 4.1 0.0014 18.9 4.1 2.3 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus MotA_ExbB PF01618.16 EST45981.1 - 0.011 15.5 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family DUF5483 PF17581.2 EST45981.1 - 0.029 13.3 3.0 0.036 13.0 3.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5483) ATP_bind_3 PF01171.20 EST45981.1 - 0.053 13.3 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 PP-loop family DUF5097 PF17020.5 EST45981.1 - 0.08 13.3 2.2 0.13 12.6 0.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5097) MutS_III PF05192.18 EST45981.1 - 0.3 11.3 1.3 0.5 10.6 1.3 1.7 1 1 0 1 1 1 0 MutS domain III LRR_4 PF12799.7 EST45982.1 - 3.7e-09 36.7 17.5 0.01 16.2 0.9 4.8 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EST45982.1 - 0.0029 17.3 10.8 0.26 11.1 1.3 4.1 3 1 1 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 EST45982.1 - 0.0032 17.4 4.5 3.4 8.0 0.1 5.0 5 0 0 5 5 5 1 Leucine Rich repeat LRR_1 PF00560.33 EST45982.1 - 0.013 15.9 13.9 6.2 7.8 0.4 6.5 6 2 0 6 6 6 0 Leucine Rich Repeat Pentapeptide_4 PF13599.6 EST45982.1 - 0.21 11.8 3.7 0.33 11.1 1.2 2.5 2 1 1 3 3 3 0 Pentapeptide repeats (9 copies) Cyclin PF08613.11 EST45982.1 - 1.2 9.5 7.1 4 7.8 1.1 2.6 1 1 1 2 2 2 0 Cyclin SH3_1 PF00018.28 EST45983.1 - 3.4e-10 39.4 0.1 7.1e-10 38.3 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EST45983.1 - 3.1e-06 27.0 0.3 1.3e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 EST45983.1 - 0.00028 20.5 0.0 0.0006 19.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain TolA_bind_tri PF16331.5 EST45984.1 - 2.3 8.4 16.2 0.27 11.4 2.1 3.0 1 1 1 2 2 2 0 TolA binding protein trimerisation Bystin PF05291.11 EST45985.1 - 1.3e-54 185.5 0.5 1.8e-54 185.0 0.5 1.1 1 0 0 1 1 1 1 Bystin DUF1831 PF08866.10 EST45989.1 - 0.046 14.2 0.4 0.077 13.5 0.4 1.4 1 0 0 1 1 1 0 Putative amino acid metabolism N-SET PF11764.8 EST45989.1 - 0.1 12.7 4.8 0.48 10.5 0.1 2.4 1 1 1 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component N PRKG1_interact PF15898.5 EST45989.1 - 1.3 9.9 8.7 0.61 11.0 3.1 2.4 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Alg14 PF08660.11 EST45990.1 - 1.8e-37 128.9 0.0 2.9e-37 128.3 0.0 1.3 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Glyco_transf_28 PF03033.20 EST45990.1 - 0.013 15.6 0.1 0.017 15.2 0.1 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Dynein_light PF01221.18 EST45991.1 - 3.5e-32 110.5 0.6 3.9e-32 110.4 0.6 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 SH3_1 PF00018.28 EST45992.1 - 5e-10 38.8 0.1 1e-09 37.8 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EST45992.1 - 3.3e-05 23.5 0.0 7.8e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EST45992.1 - 4.8e-05 23.1 0.0 0.0001 22.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain THOC7 PF05615.13 EST45992.1 - 0.0024 18.2 3.0 0.0024 18.2 3.0 2.4 1 1 0 2 2 2 1 Tho complex subunit 7 His_Phos_2 PF00328.22 EST45994.1 - 6.2e-55 187.1 7.5 1e-31 110.7 0.3 3.2 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 EST45994.1 - 1.1e-24 86.3 0.7 4.8e-24 84.3 0.7 2.2 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain CCDC24 PF15669.5 EST45994.1 - 0.07 13.0 1.3 8.3 6.2 0.0 2.8 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 24 family YkyB PF14177.6 EST45995.1 - 0.053 13.8 0.3 0.053 13.8 0.3 2.2 2 1 1 3 3 3 0 YkyB-like protein Tam41_Mmp37 PF09139.11 EST45995.1 - 0.12 11.8 6.3 0.19 11.1 6.3 1.3 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial SWIRM-assoc_3 PF16498.5 EST45995.1 - 0.14 12.4 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 SWIRM-associated domain at the C-terminal LMBR1 PF04791.16 EST45995.1 - 2.4 7.0 8.5 2.9 6.7 8.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein betaPIX_CC PF16523.5 EST45995.1 - 2.6 7.9 9.7 0.24 11.3 4.4 2.1 2 1 0 2 2 2 0 betaPIX coiled coil DUF1635 PF07795.11 EST45995.1 - 8.8 6.1 18.2 0.15 11.9 10.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1635) DUF445 PF04286.12 EST45995.1 - 9.3 5.9 11.7 16 5.2 11.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) Pkinase PF00069.25 EST45998.1 - 1.5e-76 257.3 0.1 3.2e-76 256.2 0.1 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST45998.1 - 6e-44 150.3 0.0 8.4e-44 149.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EST45998.1 - 5.8e-09 35.7 0.0 8.7e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EST45998.1 - 2.1e-05 24.2 0.5 3.9e-05 23.3 0.5 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EST45998.1 - 5.3e-05 22.7 0.3 9.7e-05 21.8 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EST45998.1 - 0.00011 21.3 1.8 0.00021 20.4 1.8 1.6 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EST45998.1 - 0.00048 20.1 0.3 0.0017 18.3 0.3 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 EST45998.1 - 0.017 14.6 0.2 0.17 11.4 0.1 2.1 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL HECT PF00632.25 EST45999.1 - 8.7e-18 64.8 0.5 1.9e-17 63.7 0.5 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF2339 PF10101.9 EST45999.1 - 0.0057 15.3 9.7 0.008 14.8 9.7 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) Epimerase PF01370.21 EST46000.1 - 1.4e-10 41.0 0.1 3.3e-10 39.9 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EST46000.1 - 4.2e-06 26.1 0.0 0.017 14.2 0.0 2.0 2 0 0 2 2 2 2 RmlD substrate binding domain NAD_binding_4 PF07993.12 EST46000.1 - 0.00012 21.3 0.1 0.11 11.7 0.0 2.7 1 1 2 3 3 3 2 Male sterility protein GDP_Man_Dehyd PF16363.5 EST46000.1 - 0.0081 15.6 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase DapB_N PF01113.20 EST46000.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Qua1 PF16274.5 EST46001.1 - 0.17 11.7 0.0 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 Qua1 domain Thioredoxin PF00085.20 EST46002.1 - 1e-10 41.5 0.2 1.2e-10 41.3 0.2 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 EST46002.1 - 1.7e-10 40.7 0.2 2.4e-10 40.3 0.2 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EST46002.1 - 7.6e-09 35.8 0.3 0.00044 20.5 0.1 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EST46002.1 - 6.3e-06 26.6 0.1 8.7e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 EST46002.1 - 0.00035 20.5 0.1 0.00045 20.1 0.1 1.0 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 EST46002.1 - 0.0023 18.1 0.3 0.0055 16.9 0.3 1.6 1 1 0 1 1 1 1 Thioredoxin-like DUF953 PF06110.11 EST46002.1 - 0.0074 15.9 0.1 0.0089 15.6 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Glutaredoxin PF00462.24 EST46002.1 - 0.016 15.4 0.5 0.06 13.6 0.5 1.9 1 1 0 1 1 1 0 Glutaredoxin RST PF12174.8 EST46002.1 - 0.037 13.9 0.1 0.06 13.3 0.1 1.3 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain AhpC-TSA PF00578.21 EST46002.1 - 0.087 12.7 0.1 0.14 12.1 0.1 1.4 1 1 0 1 1 1 0 AhpC/TSA family TPR_12 PF13424.6 EST46003.1 - 0.042 14.1 0.2 0.64 10.3 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat NOA36 PF06524.12 EST46003.1 - 0.63 9.3 6.8 1.1 8.6 6.8 1.3 1 0 0 1 1 1 0 NOA36 protein zf-HIT PF04438.16 EST46003.1 - 8.1 6.4 13.5 18 5.3 13.5 1.6 1 0 0 1 1 1 0 HIT zinc finger Gal4_dimer PF03902.13 EST46004.1 - 0.089 13.0 0.6 0.3 11.3 0.6 1.9 1 0 0 1 1 1 0 Gal4-like dimerisation domain Rer1 PF03248.13 EST46005.1 - 1.5e-28 99.6 12.7 2.6e-28 98.9 12.7 1.3 1 1 0 1 1 1 1 Rer1 family Tweety PF04906.13 EST46005.1 - 0.049 12.3 0.0 0.071 11.8 0.0 1.3 1 0 0 1 1 1 0 Tweety Wzy_C PF04932.15 EST46005.1 - 5.7 6.6 8.4 14 5.3 8.4 1.6 1 1 0 1 1 1 0 O-Antigen ligase Thoc2 PF11732.8 EST46007.1 - 1.2 9.2 6.6 0.5 10.5 0.2 3.6 3 0 0 3 3 3 0 Transcription- and export-related complex subunit Asp23 PF03780.13 EST46008.1 - 0.14 12.6 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 Asp23 family, cell envelope-related function Sec2p PF06428.11 EST46008.1 - 0.36 10.8 5.0 0.28 11.2 0.5 2.5 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p EF-hand_7 PF13499.6 EST46010.1 - 0.011 16.1 9.4 0.46 11.0 2.2 3.3 2 1 1 3 3 3 0 EF-hand domain pair EF-hand_1 PF00036.32 EST46010.1 - 0.026 14.1 6.0 1.3 8.8 0.0 4.3 4 0 0 4 4 4 0 EF hand Ank_2 PF12796.7 EST46011.1 - 6.8e-30 103.5 0.8 2.1e-10 41.1 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EST46011.1 - 2.5e-14 53.5 0.3 0.0027 18.2 0.0 6.1 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EST46011.1 - 8.3e-14 50.4 0.0 0.015 15.8 0.0 6.8 7 0 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 EST46011.1 - 3e-11 43.2 0.1 0.16 12.5 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 EST46011.1 - 8.5e-07 29.1 0.0 0.83 10.0 0.1 4.7 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Lebercilin PF15619.6 EST46011.1 - 0.002 17.8 65.0 0.076 12.7 17.1 3.8 2 1 1 3 3 3 2 Ciliary protein causing Leber congenital amaurosis disease DUF3015 PF11220.8 EST46012.1 - 0.11 12.4 0.8 0.36 10.7 0.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3015) Tap-RNA_bind PF09162.10 EST46012.1 - 0.18 11.6 0.1 0.18 11.6 0.1 3.7 3 0 0 3 3 3 0 Tap, RNA-binding ORF11CD3 PF10549.9 EST46012.1 - 3.4 7.9 7.0 20 5.4 0.8 3.7 3 0 0 3 3 3 0 ORF11CD3 domain DUF2666 PF10869.8 EST46013.1 - 0.033 14.4 0.1 0.96 9.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2666) PHD PF00628.29 EST46014.1 - 0.00019 21.2 25.4 0.0042 17.0 8.8 3.7 2 1 1 3 3 3 2 PHD-finger PHD_2 PF13831.6 EST46014.1 - 0.0097 15.4 0.9 0.0097 15.4 0.9 4.8 5 1 0 5 5 5 2 PHD-finger Actin PF00022.19 EST46015.1 - 2.2e-06 26.5 0.0 3.4e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Actin Glycos_transf_4 PF00953.21 EST46017.1 - 4.7e-26 91.7 8.4 4.7e-26 91.7 8.4 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 4 SMI1_KNR4 PF09346.10 EST46019.1 - 0.0007 20.0 0.8 0.01 16.2 0.1 2.1 1 1 1 2 2 2 1 SMI1 / KNR4 family (SUKH-1) EcoRII-C PF09019.11 EST46019.1 - 0.015 15.4 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 EcoRII C terminal Sec1 PF00995.23 EST46020.1 - 5.7e-20 72.1 17.2 6.7e-20 71.8 17.2 1.0 1 0 0 1 1 1 1 Sec1 family Myb_DNA-binding PF00249.31 EST46021.1 - 1.4e-20 73.2 5.6 4.9e-10 39.5 0.5 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST46021.1 - 3.2e-16 59.3 7.6 8.6e-11 41.9 3.1 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EST46021.1 - 0.00012 22.0 1.7 0.16 12.0 0.1 2.6 1 1 1 2 2 2 2 SLIDE Rap1_C PF11626.8 EST46021.1 - 0.027 14.5 0.1 0.056 13.5 0.1 1.5 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 EST46021.1 - 0.047 14.1 2.2 0.047 14.1 2.2 3.4 2 2 1 3 3 3 0 Myb/SANT-like DNA-binding domain NID PF07292.13 EST46021.1 - 0.13 12.9 1.4 0.24 12.1 0.1 2.0 2 0 0 2 2 2 0 Nmi/IFP 35 domain (NID) YpmT PF17431.2 EST46022.1 - 0.11 12.5 1.1 0.18 11.9 0.3 1.6 2 0 0 2 2 2 0 Uncharacterized YmpT-like Dynamin_M PF01031.20 EST46023.1 - 6.6e-86 288.1 0.9 1e-85 287.5 0.9 1.2 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EST46023.1 - 3.7e-47 160.5 0.0 7e-47 159.6 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 EST46023.1 - 1.4e-24 86.1 0.9 3.5e-24 84.8 0.9 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EST46023.1 - 2e-05 24.7 0.0 6.6e-05 23.0 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 EST46023.1 - 0.067 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Fcf1 PF04900.12 EST46024.1 - 4.4e-30 104.0 1.2 5.9e-30 103.6 1.2 1.2 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 EST46024.1 - 8e-15 55.2 0.0 1.2e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 PIN like domain KTI12 PF08433.10 EST46024.1 - 0.081 12.4 0.9 0.085 12.3 0.9 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 zf-RING_2 PF13639.6 EST46025.1 - 9.1e-12 45.1 10.6 1.5e-11 44.4 9.1 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EST46025.1 - 2.3e-09 36.9 9.2 2.7e-09 36.7 7.3 2.2 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EST46025.1 - 1.5e-08 34.8 8.9 4.6e-08 33.2 8.9 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EST46025.1 - 2.5e-07 30.4 9.8 2.5e-07 30.4 9.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EST46025.1 - 1.4e-06 28.1 11.0 3.3e-06 26.9 11.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EST46025.1 - 7.6e-06 25.8 8.2 0.00012 22.0 8.8 2.6 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EST46025.1 - 2.4e-05 24.1 8.8 2.4e-05 24.1 8.8 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EST46025.1 - 2.9e-05 23.7 6.6 2.9e-05 23.7 6.6 2.9 3 0 0 3 3 2 1 RING-like zinc finger zf-ANAPC11 PF12861.7 EST46025.1 - 0.00027 20.9 3.2 0.00061 19.8 3.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 EST46025.1 - 0.0024 17.7 4.5 0.0024 17.7 4.5 1.7 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3H2C3 PF17122.5 EST46025.1 - 0.0028 17.6 4.7 0.0087 16.1 4.7 1.9 1 0 0 1 1 1 1 Zinc-finger Zn_ribbon_17 PF17120.5 EST46025.1 - 0.003 17.2 6.6 0.0064 16.1 6.6 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 EST46025.1 - 0.0085 15.9 10.8 0.022 14.6 10.8 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 EST46025.1 - 0.039 13.8 9.3 0.04 13.7 7.7 1.9 2 1 0 2 2 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 EST46025.1 - 0.066 13.4 8.1 0.17 12.0 8.1 1.7 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 EST46025.1 - 0.5 10.7 6.7 1.4 9.2 6.7 1.8 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.6 EST46025.1 - 2.5 8.3 11.2 7.3 6.8 11.2 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 EST46025.1 - 4.1 7.7 11.2 55 4.0 11.2 2.7 1 1 0 1 1 1 0 FANCL C-terminal domain EF-hand_6 PF13405.6 EST46027.1 - 1.2e-07 31.0 1.8 0.2 11.7 0.0 3.7 3 1 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 EST46027.1 - 5.5e-05 23.5 3.3 0.0028 18.1 0.9 2.6 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EST46027.1 - 0.0002 20.7 0.1 1.7 8.4 0.0 3.8 3 0 0 3 3 3 2 EF hand EF-hand_14 PF17959.1 EST46027.1 - 0.0011 19.2 4.9 0.017 15.4 0.6 2.6 2 2 0 2 2 2 1 EF-hand domain DNA_pol3_a_NII PF11490.8 EST46027.1 - 0.0045 16.9 2.0 0.7 9.8 0.2 2.3 2 0 0 2 2 2 2 DNA polymerase III polC-type N-terminus II Pox_MCEL PF03291.16 EST46027.1 - 0.022 13.9 0.1 0.035 13.2 0.0 1.3 1 1 0 1 1 1 0 mRNA capping enzyme HeH PF12949.7 EST46027.1 - 0.058 13.1 0.6 0.65 9.8 0.0 2.7 3 0 0 3 3 3 0 HeH/LEM domain EF-hand_4 PF12763.7 EST46027.1 - 0.97 9.4 5.1 0.62 10.1 2.3 2.0 1 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand ANAPC4_WD40 PF12894.7 EST46028.1 - 4.2e-05 23.8 0.2 0.66 10.3 0.0 5.0 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_7 PF13499.6 EST46028.1 - 8.4e-05 22.9 0.2 0.00092 19.6 0.3 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EST46028.1 - 0.00063 19.1 0.7 0.0021 17.5 0.7 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EST46028.1 - 0.00068 19.4 0.1 0.0042 16.9 0.1 2.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 EST46028.1 - 0.028 14.3 0.4 0.087 12.7 0.4 1.8 1 0 0 1 1 1 0 EF-hand domain pair Atypical_Card PF18461.1 EST46028.1 - 0.077 13.2 0.5 4.3 7.6 0.0 3.2 3 0 0 3 3 3 0 Atypical caspase recruitment domain EF-hand_5 PF13202.6 EST46028.1 - 0.11 12.1 1.6 0.34 10.5 1.6 1.9 1 0 0 1 1 1 0 EF hand Synaptobrevin PF00957.21 EST46029.1 - 1.2e-09 37.8 0.4 3.7e-09 36.3 0.1 1.8 2 0 0 2 2 2 1 Synaptobrevin PCI PF01399.27 EST46029.1 - 0.016 15.7 1.0 5.9 7.5 0.0 2.4 2 1 0 2 2 2 0 PCI domain Glyco_hydro_67N PF03648.14 EST46029.1 - 0.055 13.7 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 N-terminus HHH_3 PF12836.7 EST46029.1 - 0.086 13.1 0.4 7 7.0 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF3961 PF13106.6 EST46029.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) LRR_8 PF13855.6 EST46030.1 - 4.6e-06 26.3 7.3 1.2e-05 24.9 2.8 3.1 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EST46030.1 - 4.3e-05 23.8 13.3 5.7e-05 23.4 3.2 4.5 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) HTH_45 PF14947.6 EST46030.1 - 0.014 15.3 0.2 0.11 12.5 0.1 2.7 2 0 0 2 2 2 0 Winged helix-turn-helix UBM PF14377.6 EST46030.1 - 0.13 11.8 0.2 0.38 10.3 0.2 1.8 1 0 0 1 1 1 0 Ubiquitin binding region LRR_1 PF00560.33 EST46030.1 - 0.56 11.0 8.1 1.1 10.1 0.5 4.7 4 0 0 4 4 4 0 Leucine Rich Repeat Myb_DNA-binding PF00249.31 EST46031.1 - 5.6e-19 68.1 3.9 1.8e-10 40.8 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST46031.1 - 4e-12 46.2 7.6 2.9e-06 27.4 1.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST46031.1 - 2.5e-05 24.1 2.0 2.5e-05 24.1 2.0 2.3 1 1 1 2 2 2 1 Myb DNA-binding like Pik1 PF11522.8 EST46032.1 - 0.043 13.8 4.3 0.11 12.5 0.6 2.8 2 0 0 2 2 2 0 Yeast phosphatidylinositol-4-OH kinase Pik1 AIF_C PF14721.6 EST46032.1 - 0.12 12.8 0.9 0.69 10.3 0.1 2.2 1 1 1 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF1192 PF06698.11 EST46033.1 - 0.046 13.8 8.4 0.084 12.9 0.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) FERM_N_2 PF18038.1 EST46033.1 - 0.063 14.1 1.5 0.063 14.1 1.5 2.6 1 1 1 2 2 2 0 FERM N-terminal domain Elf1 PF05129.13 EST46033.1 - 1.2 9.2 4.0 3.8 7.6 4.0 2.0 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like HalX PF08663.10 EST46033.1 - 3.3 8.1 11.2 1.1 9.7 0.6 3.7 2 1 1 3 3 3 0 HalX domain Helicase_IV_N PF12462.8 EST46035.1 - 0.0015 18.5 5.0 0.0018 18.3 5.0 1.1 1 0 0 1 1 1 1 DNA helicase IV / RNA helicase N terminal ALO PF04030.14 EST46035.1 - 0.0087 15.9 1.1 0.01 15.7 1.1 1.0 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase Telomere_reg-2 PF10193.9 EST46035.1 - 0.02 15.3 1.1 0.031 14.7 1.0 1.3 1 1 0 1 1 1 0 Telomere length regulation protein ZapB PF06005.12 EST46035.1 - 0.028 14.9 0.1 0.028 14.9 0.1 2.4 2 1 0 2 2 2 0 Cell division protein ZapB DUF2730 PF10805.8 EST46035.1 - 0.03 14.4 1.3 0.041 14.0 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) HR1 PF02185.16 EST46035.1 - 0.27 11.4 4.7 0.45 10.7 1.5 2.1 2 0 0 2 2 2 0 Hr1 repeat PspA_IM30 PF04012.12 EST46035.1 - 0.46 10.0 5.9 6.3 6.3 5.9 2.0 1 1 1 2 2 2 0 PspA/IM30 family RRF_GI PF12614.8 EST46035.1 - 0.47 10.6 4.2 0.65 10.2 2.1 1.8 1 1 1 2 2 2 0 Ribosome recycling factor DUF4064 PF13273.6 EST46036.1 - 3e-05 24.2 0.5 4.4e-05 23.7 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) CD20 PF04103.15 EST46036.1 - 0.0052 16.9 0.3 0.0074 16.4 0.3 1.3 1 1 0 1 1 1 1 CD20-like family Frizzled PF01534.17 EST46036.1 - 0.016 14.3 0.3 0.019 14.0 0.3 1.2 1 0 0 1 1 1 0 Frizzled/Smoothened family membrane region DUF390 PF04094.14 EST46037.1 - 0.72 8.1 5.1 0.88 7.8 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF390) LRR_9 PF14580.6 EST46038.1 - 3.7e-05 23.3 3.2 3.7e-05 23.3 3.2 2.7 3 0 0 3 3 3 1 Leucine-rich repeat LRR_4 PF12799.7 EST46038.1 - 6.8e-05 23.2 8.5 0.00037 20.8 3.2 3.0 2 1 1 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EST46038.1 - 0.00025 20.7 4.7 0.00031 20.4 3.2 2.0 2 0 0 2 2 2 1 Leucine rich repeat Myb_DNA-bind_7 PF15963.5 EST46041.1 - 2.7e-05 24.0 0.4 4.4e-05 23.3 0.4 1.4 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 EST46041.1 - 4.9e-05 23.4 0.7 0.0002 21.5 0.0 2.3 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST46041.1 - 0.062 13.6 0.9 0.26 11.6 0.2 2.2 1 1 1 2 2 2 0 Myb-like DNA-binding domain eIF2A PF08662.11 EST46044.1 - 1.4e-05 25.1 0.7 0.00013 21.9 0.2 2.7 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Guanylate_cyc PF00211.20 EST46045.1 - 1.4e-33 116.1 0.3 2.1e-20 73.1 0.1 2.8 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain DUF92 PF01940.16 EST46046.1 - 1.2e-39 136.1 7.5 2.1e-39 135.3 7.5 1.4 1 0 0 1 1 1 1 Integral membrane protein DUF92 PhoR PF11808.8 EST46046.1 - 0.47 10.9 1.6 4.2 7.8 0.0 3.0 3 0 0 3 3 3 0 Phosphate regulon sensor protein PhoR DUF732 PF05305.14 EST46049.1 - 0.17 12.3 0.0 14 6.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF732) Dynein_light PF01221.18 EST46051.1 - 2.9e-18 66.0 0.0 3.3e-18 65.8 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 F420_ligase PF01996.16 EST46051.1 - 0.02 14.3 0.0 0.02 14.2 0.0 1.1 1 0 0 1 1 1 0 F420-0:Gamma-glutamyl ligase DUF815 PF05673.13 EST46052.1 - 3.4e-05 23.1 0.0 6.5e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 EST46052.1 - 0.00018 21.9 0.0 0.0004 20.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 EST46052.1 - 0.003 17.5 0.4 0.0091 15.9 0.0 1.9 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 EST46052.1 - 0.0036 17.3 0.1 0.011 15.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain MIT PF04212.18 EST46052.1 - 0.0098 15.9 0.3 0.027 14.6 0.1 1.9 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA PF00004.29 EST46052.1 - 0.01 16.3 0.6 0.019 15.4 0.1 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 EST46052.1 - 0.08 13.0 0.9 0.21 11.7 0.2 2.3 2 1 0 2 2 2 0 50S ribosome-binding GTPase tRNA_NucTran2_2 PF13735.6 EST46052.1 - 0.71 9.9 4.9 2.7 7.9 0.9 2.9 2 1 0 2 2 2 0 tRNA nucleotidyltransferase domain 2 putative Gin PF10764.9 EST46053.1 - 0.038 14.0 3.9 0.097 12.6 3.9 1.7 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin RNB PF00773.19 EST46054.1 - 1.6e-85 287.3 1.1 3.4e-85 286.3 1.1 1.5 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 EST46054.1 - 2.4e-08 33.9 0.0 6.6e-08 32.5 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 EST46054.1 - 0.0062 16.7 0.0 0.023 14.9 0.0 2.0 2 0 0 2 2 2 1 Cold shock domain P53_C PF11619.8 EST46055.1 - 0.077 13.1 0.0 0.27 11.3 0.0 1.8 2 0 0 2 2 2 0 Transcription factor P53 - C terminal domain RNA_helicase PF00910.22 EST46055.1 - 0.1 13.0 0.1 0.15 12.5 0.1 1.4 1 1 0 1 1 1 0 RNA helicase ANAPC4_WD40 PF12894.7 EST46056.1 - 1.3e-14 54.2 0.3 0.0078 16.5 0.0 6.6 4 1 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EST46056.1 - 3.4e-08 34.0 6.5 7.1 7.7 0.0 7.9 8 0 0 8 8 8 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 EST46056.1 - 0.012 14.7 1.5 0.095 11.7 0.1 2.9 3 1 0 4 4 4 0 Coatomer WD associated region SUKH_6 PF14568.6 EST46056.1 - 0.03 14.7 0.1 1.9 8.9 0.0 3.4 3 0 0 3 3 3 0 SMI1-KNR4 cell-wall Frtz PF11768.8 EST46056.1 - 0.066 11.5 0.3 2.6 6.2 0.0 2.7 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF2442 PF10387.9 EST46056.1 - 0.068 13.5 0.1 49 4.3 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2442) PQQ PF01011.21 EST46056.1 - 0.13 12.3 0.7 70 3.6 0.0 4.1 4 0 0 4 4 4 0 PQQ enzyme repeat IMS PF00817.20 EST46057.1 - 8e-39 133.0 0.1 1.5e-38 132.1 0.1 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 EST46057.1 - 1.1e-08 35.8 0.0 3.4e-08 34.2 0.0 1.8 1 1 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 EST46057.1 - 0.0022 18.2 0.0 0.0068 16.7 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif DNA_pol_lambd_f PF10391.9 EST46057.1 - 0.09 12.6 0.0 0.31 10.9 0.0 1.9 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda FERM_M PF00373.18 EST46060.1 - 2e-09 37.9 0.0 3.9e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 FERM central domain DUF4087 PF13316.6 EST46060.1 - 0.15 12.6 0.2 0.33 11.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4087) Acetyltransf_10 PF13673.7 EST46063.1 - 6.5e-08 32.6 0.0 7.6e-08 32.4 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EST46063.1 - 2.6e-05 24.5 0.0 3.2e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EST46063.1 - 0.0011 19.2 0.0 0.0013 19.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family TPR_2 PF07719.17 EST46064.1 - 5.5e-12 44.8 8.5 0.067 13.3 0.0 4.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 EST46064.1 - 4.6e-08 32.5 9.3 0.056 13.3 0.1 4.8 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 EST46064.1 - 1.2e-07 31.9 10.2 0.062 13.6 0.8 4.3 3 1 0 4 4 4 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EST46064.1 - 1e-05 25.1 5.2 0.00013 21.5 0.1 2.9 1 1 3 4 4 4 1 MalT-like TPR region TPR_8 PF13181.6 EST46064.1 - 0.0016 18.5 2.9 2 8.8 0.1 3.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EST46064.1 - 0.0022 17.9 6.8 0.8 9.9 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 EST46064.1 - 0.25 11.3 6.1 7.4 6.6 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 EST46064.1 - 2.2 9.0 6.4 27 5.5 0.9 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EST46064.1 - 3.1 8.6 6.6 59 4.6 0.2 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat Colipase-like PF15083.6 EST46065.1 - 0.0096 16.0 0.9 0.017 15.2 0.9 1.5 1 0 0 1 1 1 1 Colipase-like DX PF01666.17 EST46065.1 - 0.19 12.2 2.7 0.29 11.6 1.9 1.7 2 0 0 2 2 2 0 DX module Annexin PF00191.20 EST46067.1 - 7e-50 167.0 2.4 3.1e-19 68.8 0.0 4.9 4 1 0 4 4 4 4 Annexin DUF3243 PF11588.8 EST46067.1 - 0.097 13.0 0.6 12 6.3 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3243) DEAD PF00270.29 EST46069.1 - 7.6e-45 152.8 0.2 2.4e-44 151.2 0.2 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EST46069.1 - 1.8e-23 83.0 1.7 1.1e-22 80.5 0.0 3.2 3 1 1 4 4 4 1 Helicase conserved C-terminal domain Flavi_DEAD PF07652.14 EST46069.1 - 0.025 14.6 0.0 0.64 10.0 0.0 2.6 2 0 0 2 2 2 0 Flavivirus DEAD domain DUF2178 PF09946.9 EST46069.1 - 0.23 11.7 0.2 0.48 10.6 0.2 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) Kinesin PF00225.23 EST46070.1 - 1.3e-93 313.6 6.4 1.3e-93 313.6 6.4 4.6 4 2 0 5 5 5 1 Kinesin motor domain Microtub_bd PF16796.5 EST46070.1 - 1.4e-19 70.5 2.4 1.4e-19 70.5 2.4 6.2 5 2 2 7 7 7 1 Microtubule binding HJURP_C PF12347.8 EST46070.1 - 0.012 15.6 1.5 0.012 15.6 1.5 2.8 2 0 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat CNOT1_TTP_bind PF16417.5 EST46073.1 - 0.0039 16.4 0.7 0.0043 16.3 0.7 1.1 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain AAA_13 PF13166.6 EST46073.1 - 0.012 14.3 1.1 0.013 14.2 1.1 1.0 1 0 0 1 1 1 0 AAA domain CHASE3 PF05227.13 EST46073.1 - 0.019 14.9 0.1 0.021 14.7 0.1 1.2 1 0 0 1 1 1 0 CHASE3 domain Med11 PF10280.9 EST46073.1 - 0.019 15.4 1.2 0.021 15.3 1.2 1.2 1 0 0 1 1 1 0 Mediator complex protein HeLo PF14479.6 EST46073.1 - 0.037 13.8 2.5 0.042 13.7 1.5 1.6 1 1 1 2 2 2 0 Prion-inhibition and propagation Baculo_PEP_C PF04513.12 EST46073.1 - 0.055 13.5 5.5 0.067 13.2 5.5 1.3 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mating_N PF12731.7 EST46073.1 - 0.076 13.1 2.8 0.51 10.5 2.7 2.1 1 1 0 1 1 1 0 Mating-type protein beta 1 DASH_Dad1 PF08649.10 EST46073.1 - 0.29 11.4 4.2 0.13 12.4 1.1 2.0 2 0 0 2 2 2 0 DASH complex subunit Dad1 GCV_H PF01597.19 EST46074.1 - 0.00024 21.0 0.0 0.00034 20.5 0.0 1.5 1 1 0 1 1 1 1 Glycine cleavage H-protein RasGAP_C PF03836.15 EST46075.1 - 0.65 10.1 8.7 0.19 11.9 0.8 3.1 1 1 1 2 2 2 0 RasGAP C-terminus DUF5339 PF17274.2 EST46075.1 - 0.78 10.6 6.4 34 5.4 3.7 3.1 2 1 0 2 2 2 0 Family of unknown function (DUF5339) IF4E PF01652.18 EST46078.1 - 6.8e-20 71.5 2.5 8.4e-20 71.2 2.5 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DEAD PF00270.29 EST46080.1 - 1.1e-31 109.9 3.5 1.1e-31 109.9 3.5 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EST46080.1 - 2.9e-27 95.2 6.4 1.1e-26 93.3 0.8 3.1 2 1 0 3 3 3 1 Helicase conserved C-terminal domain CAF1 PF04857.20 EST46081.1 - 1.9e-18 66.7 0.1 5.4e-18 65.2 0.1 1.7 1 1 0 1 1 1 1 CAF1 family ribonuclease Med26 PF08711.11 EST46083.1 - 3.4 7.8 7.6 3.2 7.9 0.0 3.7 3 1 0 3 3 3 0 TFIIS helical bundle-like domain TSC22 PF01166.18 EST46083.1 - 5.1 7.5 15.3 16 5.9 6.7 4.2 3 1 0 3 3 3 0 TSC-22/dip/bun family DUF4934 PF16288.5 EST46084.1 - 0.051 13.5 0.2 0.1 12.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4934) WD40 PF00400.32 EST46086.1 - 8.1e-06 26.5 3.4 1.4 9.9 0.1 5.6 7 0 0 7 7 7 2 WD domain, G-beta repeat WD40_like PF17005.5 EST46086.1 - 0.00018 21.0 1.0 0.23 10.7 0.0 2.4 2 1 0 2 2 2 2 WD40-like domain Clathrin_propel PF01394.20 EST46086.1 - 0.16 12.4 1.5 2.3 8.7 0.2 3.2 3 0 0 3 3 3 0 Clathrin propeller repeat Ribosomal_S6e PF01092.19 EST46087.1 - 0.063 13.3 0.0 5.7 6.9 0.0 2.7 1 1 1 2 2 2 0 Ribosomal protein S6e Rtt106 PF08512.12 EST46088.1 - 9.4e-07 29.2 2.6 0.00012 22.4 0.2 3.1 3 0 0 3 3 3 2 Histone chaperone Rttp106-like SSrecog PF03531.14 EST46088.1 - 0.082 12.8 4.8 2 8.4 0.0 3.4 4 0 0 4 4 4 0 Structure-specific recognition protein (SSRP1) UQ_con PF00179.26 EST46090.1 - 2.8e-14 52.9 0.0 5.7e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Kinesin PF00225.23 EST46091.1 - 2.5e-89 299.5 6.9 2.5e-89 299.5 6.9 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EST46091.1 - 1.7e-22 80.0 1.8 1.3e-21 77.1 1.8 2.6 1 0 0 1 1 1 1 Microtubule binding BLOC1_2 PF10046.9 EST46091.1 - 0.0091 16.3 2.3 0.0091 16.3 2.3 4.6 4 1 1 5 5 5 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3656 PF12392.8 EST46091.1 - 0.062 14.0 0.2 0.062 14.0 0.2 2.6 2 1 0 2 2 2 0 Collagenase Formin_GBD_N PF18382.1 EST46091.1 - 1.4 9.4 5.4 4.3 7.8 0.2 3.3 3 0 0 3 3 3 0 Formin N-terminal GTPase-binding domain LRR_5 PF13306.6 EST46094.1 - 0.019 15.0 2.0 0.019 15.0 2.0 2.8 2 1 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) GMAP PF06540.11 EST46096.1 - 0.081 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Galanin message associated peptide (GMAP) MMR_HSR1 PF01926.23 EST46097.1 - 8.6e-11 41.9 0.1 6.7e-10 39.1 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EST46097.1 - 2.4e-05 23.9 0.2 0.26 10.8 0.0 2.6 3 0 0 3 3 3 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EST46097.1 - 0.00068 19.6 0.0 1.2 9.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EST46097.1 - 0.0091 15.5 0.4 1.1 8.8 0.0 3.3 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 EST46097.1 - 0.11 12.2 0.3 0.45 10.2 0.0 2.1 2 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF3887 PF13026.6 EST46099.1 - 0.0013 19.5 0.4 0.015 16.1 0.1 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3887) PSI_PsaH PF03244.14 EST46100.1 - 0.085 12.4 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VI SRRM_C PF15230.6 EST46101.1 - 0.12 13.0 1.0 3.2 8.4 0.1 2.4 1 1 0 2 2 2 0 Serine/arginine repetitive matrix protein C-terminus CBM46 PF18448.1 EST46103.1 - 0.18 12.2 1.0 0.58 10.5 0.2 2.1 2 0 0 2 2 2 0 Carbohydrate binding domain OST3_OST6 PF04756.13 EST46105.1 - 4.1e-10 39.5 0.1 4.5e-10 39.4 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Dimerisation PF08100.11 EST46106.1 - 0.13 12.2 0.1 5 7.2 0.0 2.5 2 0 0 2 2 2 0 Dimerisation domain DUF1664 PF07889.12 EST46106.1 - 0.46 10.5 5.7 0.64 10.1 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF1981 PF09324.10 EST46107.1 - 0.04 13.8 0.0 0.16 11.9 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1981) 7TMR-HDED PF07697.11 EST46108.1 - 0.11 12.6 1.5 0.74 9.9 1.5 2.0 1 1 0 1 1 1 0 7TM-HD extracellular RNase_H PF00075.24 EST46109.1 - 4.6e-05 23.6 0.0 9e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 RNase H Cnd2 PF05786.14 EST46110.1 - 1.9e-20 73.2 10.8 2.7e-14 52.8 2.2 3.5 2 2 0 2 2 2 2 Condensin complex subunit 2 HTH_40 PF14493.6 EST46110.1 - 0.21 12.1 5.0 14 6.2 0.1 3.2 2 1 1 3 3 3 0 Helix-turn-helix domain Pup PF05639.11 EST46110.1 - 2 9.4 0.0 2 9.4 0.0 3.4 3 0 0 3 3 3 0 Pup-like protein Helicase_C PF00271.31 EST46111.1 - 2.2e-11 44.1 1.4 1.3e-10 41.6 0.2 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EST46111.1 - 2.7e-09 37.0 3.0 2.9e-09 36.9 0.2 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EST46111.1 - 5.3e-08 33.2 0.1 1.6e-07 31.7 0.1 1.8 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EST46111.1 - 2.1e-05 24.6 1.2 7.6e-05 22.8 0.1 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_14 PF13173.6 EST46111.1 - 0.0013 18.8 2.3 0.0076 16.3 0.2 3.2 2 1 0 2 2 1 1 AAA domain T2SSE PF00437.20 EST46111.1 - 0.0015 17.6 0.0 0.0043 16.1 0.0 1.8 1 0 0 1 1 1 1 Type II/IV secretion system protein Rad17 PF03215.15 EST46111.1 - 0.0038 17.2 0.2 0.024 14.5 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_5 PF07728.14 EST46111.1 - 0.018 15.1 0.0 0.058 13.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 EST46111.1 - 0.019 15.5 0.1 0.081 13.4 0.0 2.1 2 0 0 2 2 1 0 ABC transporter Flavi_DEAD PF07652.14 EST46111.1 - 0.024 14.6 0.0 0.067 13.2 0.0 1.7 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_11 PF13086.6 EST46111.1 - 0.029 14.2 0.4 0.097 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EST46111.1 - 0.037 14.4 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EST46111.1 - 0.056 13.8 0.1 0.21 12.0 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain ATPase PF06745.13 EST46111.1 - 0.057 12.8 0.4 0.31 10.3 0.0 2.2 2 0 0 2 2 2 0 KaiC AAA PF00004.29 EST46111.1 - 0.077 13.4 0.1 0.44 11.0 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 EST46111.1 - 0.09 12.7 2.7 7.5 6.4 0.2 2.6 2 0 0 2 2 2 0 NTPase AAA_29 PF13555.6 EST46111.1 - 0.13 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 EST46111.1 - 0.47 11.0 2.2 11 6.6 0.3 3.3 3 0 0 3 3 3 0 AAA domain Acetyltransf_10 PF13673.7 EST46112.1 - 8e-05 22.6 0.1 0.00011 22.2 0.1 1.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EST46112.1 - 0.0015 19.0 0.3 0.0023 18.3 0.2 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EST46112.1 - 0.019 15.2 0.1 0.023 14.9 0.1 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.6 EST46112.1 - 0.15 12.8 0.0 0.2 12.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HHH_4 PF14490.6 EST46113.1 - 0.022 14.7 0.1 0.045 13.7 0.1 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix containing domain Parvo_coat PF00740.18 EST46113.1 - 0.03 13.0 0.3 0.036 12.7 0.3 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 BORCS6 PF10157.9 EST46114.1 - 0.33 11.2 3.4 1.3 9.3 0.1 2.4 2 1 1 3 3 3 0 BLOC-1-related complex sub-unit 6 OTCace PF00185.24 EST46115.1 - 0.16 12.1 0.0 0.16 12.1 0.0 3.2 2 1 0 2 2 2 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Jacalin PF01419.17 EST46115.1 - 1.7 8.5 6.1 2.6 8.0 1.1 3.2 2 1 0 2 2 2 0 Jacalin-like lectin domain Kinesin PF00225.23 EST46116.1 - 2.4e-109 365.3 8.0 2.4e-109 365.3 8.0 3.2 2 1 1 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 EST46116.1 - 1.4e-29 102.9 1.1 1.4e-29 102.9 1.1 3.8 3 1 1 4 4 4 1 Microtubule binding HMG_box_5 PF14887.6 EST46116.1 - 0.077 13.0 0.1 1 9.4 0.0 2.9 3 0 0 3 3 3 0 HMG (high mobility group) box 5 L27 PF02828.16 EST46116.1 - 1.4 8.7 4.3 1.3 8.9 0.3 3.2 3 0 0 3 3 3 0 L27 domain IL3 PF02059.15 EST46117.1 - 0.064 13.3 0.5 0.064 13.3 0.5 2.7 1 1 1 3 3 3 0 Interleukin-3 ALMT PF11744.8 EST46117.1 - 0.22 10.3 9.4 0.27 10.0 9.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter GAS PF13851.6 EST46118.1 - 0.18 11.2 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Tyr_Deacylase PF02580.16 EST46119.1 - 9.4e-44 149.4 0.0 1.2e-43 149.0 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Ras PF00071.22 EST46120.1 - 0.00051 19.7 0.0 0.0014 18.3 0.0 1.7 1 1 0 1 1 1 1 Ras family G-alpha PF00503.20 EST46120.1 - 0.065 12.4 0.1 0.15 11.2 0.0 1.4 1 1 0 1 1 1 0 G-protein alpha subunit Roc PF08477.13 EST46120.1 - 0.13 12.5 0.0 0.5 10.6 0.0 2.0 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Lactamase_B PF00753.27 EST46121.1 - 0.00096 19.2 2.2 0.001 19.1 0.7 1.9 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EST46121.1 - 0.0029 17.2 2.2 0.026 14.0 0.5 2.6 2 1 1 3 3 3 1 Beta-lactamase superfamily domain RMMBL PF07521.12 EST46121.1 - 0.03 14.2 0.0 0.086 12.8 0.0 1.7 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain Myb_DNA-binding PF00249.31 EST46122.1 - 9.5e-11 41.7 0.3 2.8e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST46122.1 - 3.6e-07 30.3 6.4 0.00025 21.2 0.9 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST46122.1 - 0.00017 21.4 0.7 0.00093 19.1 0.1 2.3 1 1 1 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EST46122.1 - 0.017 15.3 2.5 0.32 11.2 0.7 2.3 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 SDH_sah PF01972.16 EST46122.1 - 0.16 11.0 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Serine dehydrogenase proteinase DUF2028 PF09667.10 EST46123.1 - 0.26 11.2 3.6 0.67 9.9 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2028) FAD_binding_7 PF03441.14 EST46125.1 - 0.0098 15.4 1.0 0.012 15.1 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase SOBP PF15279.6 EST46125.1 - 0.36 11.4 24.9 0.46 11.0 24.9 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein NADH_4Fe-4S PF10589.9 EST46127.1 - 0.13 12.4 0.3 1.4 9.0 0.0 2.6 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region PBP3 PF18056.1 EST46127.1 - 0.16 12.1 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 Penicillin Binding Protein 3 Domain Laminin_II PF06009.12 EST46128.1 - 1.9 8.5 14.8 0.59 10.2 7.5 2.9 2 1 0 2 2 2 0 Laminin Domain II DUF1664 PF07889.12 EST46128.1 - 2.7 8.0 13.4 0.13 12.4 2.5 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HORMA PF02301.18 EST46129.1 - 7.7e-19 68.1 0.1 5.7e-12 45.7 0.1 2.1 1 1 1 2 2 2 2 HORMA domain FAP206 PF12018.8 EST46130.1 - 7.2e-14 51.9 1.1 7.2e-14 51.9 1.1 2.1 2 0 0 2 2 2 1 Domain of unknown function MucB_RseB_C PF17188.4 EST46130.1 - 0.047 13.9 0.1 0.76 10.0 0.0 2.6 2 0 0 2 2 2 0 MucB/RseB C-terminal domain DUF2000 PF09391.10 EST46130.1 - 0.14 12.1 1.4 1.4 8.8 0.1 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF2000) adh_short PF00106.25 EST46132.1 - 2.1e-11 43.6 0.0 3.3e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EST46132.1 - 1.8e-06 28.0 0.0 2.8e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EST46132.1 - 0.00084 19.3 0.0 0.0039 17.1 0.0 2.0 3 0 0 3 3 3 1 NAD(P)H-binding adh_short_C2 PF13561.6 EST46132.1 - 0.0045 16.6 0.0 0.006 16.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EST46132.1 - 0.06 12.8 0.0 2.2 7.7 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family HTH_AsnC-type PF13404.6 EST46137.1 - 0.0024 17.7 0.6 0.019 14.8 0.2 2.4 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_38 PF13936.6 EST46137.1 - 0.03 14.1 0.8 0.14 11.9 0.3 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain Ras PF00071.22 EST46138.1 - 7.2e-48 162.3 0.0 8.3e-48 162.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EST46138.1 - 3.6e-29 101.4 0.1 4.8e-29 101.0 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EST46138.1 - 1e-16 60.9 0.0 1.2e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EST46138.1 - 8.3e-09 35.1 0.0 1e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EST46138.1 - 3e-07 30.5 0.0 4.3e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EST46138.1 - 0.00017 21.2 0.0 0.0027 17.3 0.0 2.2 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EST46138.1 - 0.00062 19.7 0.0 0.26 11.2 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase Septin PF00735.18 EST46138.1 - 0.0036 16.6 0.0 0.019 14.3 0.0 1.9 2 0 0 2 2 2 1 Septin ATP_bind_1 PF03029.17 EST46138.1 - 0.0047 16.7 0.1 0.028 14.2 0.0 1.9 1 1 0 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 EST46138.1 - 0.0093 15.7 0.2 0.27 11.0 0.2 2.6 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 EST46138.1 - 0.023 15.1 0.0 0.043 14.2 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 EST46138.1 - 0.042 13.6 0.0 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EST46138.1 - 0.096 13.1 0.0 0.23 11.9 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 EST46138.1 - 0.11 11.6 1.4 0.46 9.6 0.2 2.3 1 1 1 2 2 2 0 G-protein alpha subunit SRPRB PF09439.10 EST46138.1 - 0.15 11.5 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 EST46138.1 - 0.2 11.1 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein PP2 PF14299.6 EST46139.1 - 0.062 13.3 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Phloem protein 2 Histone PF00125.24 EST46140.1 - 8.5e-12 45.6 1.0 4e-11 43.4 0.1 1.9 1 1 1 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EST46140.1 - 2.8e-08 33.9 0.1 5e-08 33.1 0.0 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-18kDa PF02269.16 EST46140.1 - 0.025 14.6 0.9 0.038 14.0 0.9 1.5 1 1 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Histone_H2A_C PF16211.5 EST46140.1 - 0.19 11.5 0.0 0.19 11.5 0.0 2.4 3 0 0 3 3 3 0 C-terminus of histone H2A tRNA-synt_2b PF00587.25 EST46145.1 - 4.1e-33 114.8 0.0 6.9e-33 114.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EST46145.1 - 5.1e-14 52.2 0.0 1.1e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain ProRS-C_1 PF09180.11 EST46145.1 - 1.3e-06 28.5 1.0 9e-06 25.8 0.4 2.6 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal DUF2309 PF10070.9 EST46145.1 - 0.012 14.0 0.1 0.019 13.3 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) VSP PF03302.13 EST46148.1 - 8.7e-12 44.6 130.8 0.008 15.1 29.1 5.9 1 1 4 5 5 5 4 Giardia variant-specific surface protein DUF4366 PF14283.6 EST46148.1 - 0.16 12.0 0.2 0.16 12.0 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) VSP PF03302.13 EST46150.1 - 1e-05 24.6 20.9 1e-05 24.6 20.9 9.1 1 1 4 7 7 7 5 Giardia variant-specific surface protein Podoplanin PF05808.11 EST46150.1 - 0.08 13.1 0.1 0.23 11.6 0.1 1.7 1 0 0 1 1 1 0 Podoplanin SMC_N PF02463.19 EST46151.1 - 9.2e-15 54.7 34.3 1.8e-12 47.1 34.3 4.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EST46151.1 - 1.4e-14 54.4 2.3 1.7e-14 54.1 0.2 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EST46151.1 - 2.1e-08 34.3 16.9 2.5e-05 24.2 0.4 3.4 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EST46151.1 - 3.6e-06 26.9 49.3 3.6e-06 26.9 49.3 4.4 2 2 1 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 EST46151.1 - 0.0011 18.7 0.0 0.0025 17.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_27 PF13514.6 EST46151.1 - 0.0064 16.1 0.0 0.0064 16.1 0.0 3.9 6 1 0 6 6 6 1 AAA domain AAA_16 PF13191.6 EST46152.1 - 0.087 13.2 0.0 0.31 11.4 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain Ribonuclease_T2 PF00445.18 EST46152.1 - 0.25 11.6 6.3 0.31 11.2 3.3 2.8 2 0 0 2 2 2 0 Ribonuclease T2 family IL31 PF15209.6 EST46156.1 - 0.05 13.4 0.1 0.06 13.1 0.1 1.1 1 0 0 1 1 1 0 Interleukin 31 Sec23_trunk PF04811.15 EST46157.1 - 2.9e-37 128.5 0.2 9.2e-37 126.9 0.1 1.8 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EST46157.1 - 8.3e-20 71.3 1.8 2.8e-19 69.6 0.1 2.6 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EST46157.1 - 1e-19 70.2 0.4 3e-19 68.8 0.4 1.9 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EST46157.1 - 1.2e-11 44.4 4.2 2.4e-11 43.5 4.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EST46157.1 - 0.0059 16.5 0.3 0.085 12.8 0.3 2.5 1 1 0 1 1 1 1 Gelsolin repeat zinc_ribbon_10 PF10058.9 EST46157.1 - 0.23 11.2 1.6 0.64 9.8 1.6 1.7 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein GIT_CC PF16559.5 EST46157.1 - 0.51 10.2 3.7 4.8 7.1 0.1 3.5 4 0 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor PCI PF01399.27 EST46158.1 - 0.00014 22.3 2.4 0.00064 20.2 2.3 2.2 1 1 0 1 1 1 1 PCI domain TPR_2 PF07719.17 EST46158.1 - 0.056 13.6 4.0 0.38 11.0 0.6 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DYW_deaminase PF14432.6 EST46158.1 - 0.14 12.1 0.3 1.5 8.7 0.0 2.5 2 1 0 2 2 2 0 DYW family of nucleic acid deaminases GAPES3 PF17154.4 EST46158.1 - 0.4 10.7 0.1 0.4 10.7 0.1 3.1 2 1 1 3 3 3 0 Gammaproteobacterial periplasmic sensor domain RhoGAP PF00620.27 EST46159.1 - 2.2e-19 69.8 3.3 8.9e-19 67.8 3.3 2.0 2 0 0 2 2 2 1 RhoGAP domain SH3_1 PF00018.28 EST46159.1 - 3.2e-05 23.4 0.4 0.0023 17.5 0.0 2.9 3 0 0 3 3 3 1 SH3 domain SH3_2 PF07653.17 EST46159.1 - 0.00062 19.4 0.1 1.9 8.3 0.0 2.8 2 1 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.11 EST46159.1 - 0.12 12.6 1.1 0.79 10.0 0.2 2.6 2 1 0 2 2 2 0 Bacterial SH3 domain Imm-NTF2 PF15655.6 EST46159.1 - 0.87 9.9 5.7 8.6 6.7 0.5 3.5 3 1 0 3 3 3 0 NTF2 fold immunity protein EF-hand_1 PF00036.32 EST46160.1 - 0.019 14.5 0.5 0.052 13.1 0.5 1.9 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 EST46160.1 - 0.09 12.7 0.1 0.53 10.4 0.1 2.3 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 EST46160.1 - 0.097 13.1 0.2 0.87 10.1 0.1 2.7 3 0 0 3 3 3 0 EF-hand domain pair TypeIII_RM_meth PF12564.8 EST46160.1 - 0.19 11.8 3.0 0.28 11.3 0.3 2.6 2 0 0 2 2 2 0 Type III restriction/modification enzyme methylation subunit Adap_comp_sub PF00928.21 EST46161.1 - 5.1e-67 226.0 2.4 6.3e-67 225.7 2.4 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EST46161.1 - 6e-08 32.7 6.5 2.3e-07 30.8 3.9 2.4 1 1 2 3 3 3 1 Clathrin adaptor complex small chain PIN7 PF18475.1 EST46162.1 - 0.01 16.4 1.5 0.017 15.7 0.5 1.9 2 1 0 2 2 2 0 PIN domain PIN_2 PF10130.9 EST46162.1 - 0.12 12.6 1.1 0.3 11.3 0.1 2.1 1 1 0 2 2 2 0 PIN domain Homeodomain PF00046.29 EST46162.1 - 4.8 7.1 7.8 2.1 8.2 1.1 3.2 3 1 1 4 4 3 0 Homeodomain FKBP_C PF00254.28 EST46163.1 - 4.2e-30 103.9 0.0 5.2e-30 103.6 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N_2 PF18023.1 EST46163.1 - 0.021 14.9 0.0 0.038 14.1 0.0 1.5 1 1 0 1 1 1 0 BDBT FKBP like N-terminal BLOC1_2 PF10046.9 EST46164.1 - 0.077 13.3 2.4 0.17 12.2 0.2 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 vATP-synt_E PF01991.18 EST46165.1 - 3.9e-11 42.7 10.0 6.4e-09 35.5 10.0 2.0 1 1 0 1 1 1 1 ATP synthase (E/31 kDa) subunit AAA_6 PF12774.7 EST46166.1 - 7.8e-121 403.0 0.1 1.2e-119 399.1 0.0 3.2 4 0 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EST46166.1 - 1.9e-92 310.5 18.1 1.9e-92 310.5 18.1 4.8 5 0 0 5 5 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 EST46166.1 - 1.6e-86 289.8 3.5 4.8e-85 285.0 0.7 3.0 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 EST46166.1 - 1.1e-84 284.3 0.2 1.2e-81 274.3 0.0 3.3 2 0 0 2 2 2 2 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 EST46166.1 - 3e-68 229.3 1.8 3e-68 229.3 1.8 5.4 6 0 0 6 6 3 2 ATP-binding dynein motor region AAA_7 PF12775.7 EST46166.1 - 8.5e-64 214.4 2.5 3.1e-59 199.5 0.0 4.4 4 0 0 4 4 3 2 P-loop containing dynein motor region MT PF12777.7 EST46166.1 - 2.5e-41 141.9 14.9 2.5e-41 141.9 14.9 2.2 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 EST46166.1 - 9.1e-38 129.7 0.2 4.4e-37 127.4 0.2 2.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EST46166.1 - 1.2e-34 119.0 0.7 2.3e-32 111.6 0.0 4.3 4 0 0 4 4 3 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 EST46166.1 - 2.9e-19 69.4 0.0 4.4e-06 26.7 0.0 6.7 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 EST46166.1 - 1.6e-13 50.7 2.9 8.6e-13 48.4 0.1 3.9 3 0 0 3 3 3 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 EST46166.1 - 1.8e-11 44.2 4.0 6.7e-10 39.2 0.0 4.8 4 0 0 4 4 4 1 Dynein heavy chain AAA lid domain T2SSE PF00437.20 EST46166.1 - 5e-11 42.2 0.6 9.1e-05 21.6 0.0 3.9 3 1 1 4 4 4 2 Type II/IV secretion system protein AAA_16 PF13191.6 EST46166.1 - 7e-09 36.3 0.6 0.00026 21.4 0.0 5.5 5 0 0 5 5 4 1 AAA ATPase domain AAA_22 PF13401.6 EST46166.1 - 1.9e-08 34.7 0.4 0.011 16.0 0.0 5.9 4 0 0 4 4 4 1 AAA domain FtsK_SpoIIIE PF01580.18 EST46166.1 - 2.6e-05 23.7 0.5 0.012 15.0 0.1 2.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA PF00004.29 EST46166.1 - 0.00015 22.2 0.2 0.05 14.0 0.0 4.5 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 EST46166.1 - 0.0034 16.6 0.3 0.014 14.6 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_29 PF13555.6 EST46166.1 - 0.0053 16.5 1.2 0.17 11.6 0.0 3.4 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_19 PF13245.6 EST46166.1 - 0.0095 16.3 0.4 2.1 8.7 0.0 3.4 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.6 EST46166.1 - 0.012 15.3 0.2 5.9 6.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 EST46166.1 - 0.02 15.0 0.0 3.4 7.8 0.0 3.9 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 EST46166.1 - 0.023 15.3 5.5 0.98 10.0 0.0 4.2 3 0 0 3 3 2 0 AAA domain Mg_chelatase PF01078.21 EST46166.1 - 0.025 14.0 0.1 9.7 5.5 0.0 3.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 EST46166.1 - 0.042 13.9 0.2 4.4 7.3 0.0 3.7 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 EST46166.1 - 0.3 11.0 3.3 0.55 10.1 0.1 3.3 3 0 0 3 3 3 0 RsgA GTPase CdiA_C PF18451.1 EST46166.1 - 0.87 9.8 4.1 6.4 7.1 0.0 4.7 3 0 0 3 3 2 0 Contact-dependent growth inhibition CdiA C-terminal domain PGP_phosphatase PF09419.10 EST46167.1 - 0.12 11.9 0.1 0.12 11.9 0.1 2.2 2 1 0 2 2 2 0 Mitochondrial PGP phosphatase SecA_SW PF07516.13 EST46167.1 - 0.13 12.3 10.4 0.22 11.6 10.4 1.7 1 1 0 1 1 1 0 SecA Wing and Scaffold domain PepSY_TM PF03929.16 EST46167.1 - 0.21 11.2 0.1 0.3 10.7 0.1 1.1 1 0 0 1 1 1 0 PepSY-associated TM region ABC_tran PF00005.27 EST46168.1 - 4.1e-41 140.7 10.1 5.3e-22 78.8 0.1 3.5 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 EST46168.1 - 2.1e-15 57.4 17.7 2.8e-08 33.9 1.4 4.7 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EST46168.1 - 3.2e-12 46.7 0.3 1.4e-05 25.1 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase SMC_N PF02463.19 EST46168.1 - 2.1e-11 43.7 0.3 0.00036 20.1 0.0 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EST46168.1 - 5.5e-06 26.0 1.2 0.06 13.1 0.2 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_33 PF13671.6 EST46168.1 - 3.2e-05 24.1 0.0 0.073 13.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EST46168.1 - 7.3e-05 23.3 0.2 0.19 12.3 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EST46168.1 - 0.00015 22.2 1.8 0.19 12.1 0.1 3.3 3 1 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.23 EST46168.1 - 0.00025 21.1 0.5 0.83 9.8 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 EST46168.1 - 0.00097 19.4 7.7 0.11 12.8 0.3 3.7 3 2 0 3 3 3 2 AAA domain Arf PF00025.21 EST46168.1 - 0.0019 17.7 1.4 2.1 7.8 0.1 3.1 3 0 0 3 3 3 2 ADP-ribosylation factor family PduV-EutP PF10662.9 EST46168.1 - 0.0023 17.7 1.8 1.6 8.5 0.3 2.9 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.15 EST46168.1 - 0.0027 17.7 3.9 0.086 12.8 0.1 3.4 3 0 0 3 3 3 1 Rad17 P-loop domain Roc PF08477.13 EST46168.1 - 0.027 14.7 0.6 7 6.9 0.1 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 EST46168.1 - 0.029 13.6 5.5 0.29 10.3 0.0 3.1 2 1 1 3 3 3 0 NB-ARC domain NACHT PF05729.12 EST46168.1 - 0.035 14.0 1.4 10 6.0 0.0 2.8 2 0 0 2 2 2 0 NACHT domain MobB PF03205.14 EST46168.1 - 0.042 13.7 1.0 0.61 10.0 0.2 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.18 EST46168.1 - 0.085 12.6 1.1 22 4.7 0.0 3.6 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 EST46168.1 - 0.12 11.9 0.0 13 5.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EST46168.1 - 0.19 11.4 0.0 6 6.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 EST46168.1 - 0.79 8.7 10.4 0.042 12.9 0.2 3.2 4 0 0 4 4 4 0 Type II/IV secretion system protein AAA_5 PF07728.14 EST46168.1 - 1.4 8.9 4.7 30 4.6 0.1 4.0 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EST46168.1 - 2.2 8.5 4.7 26 5.0 0.9 2.4 2 0 0 2 2 2 0 AAA domain Ank_2 PF12796.7 EST46169.1 - 0.00024 21.6 0.2 0.084 13.5 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) DUF3810 PF12725.7 EST46169.1 - 0.0045 16.4 0.6 0.0045 16.4 0.6 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3810) Ank_4 PF13637.6 EST46169.1 - 0.034 14.7 0.0 0.28 11.8 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Cullin_binding PF03556.15 EST46169.1 - 0.078 13.4 0.4 0.24 11.9 0.4 1.8 1 0 0 1 1 1 0 Cullin binding DUF4535 PF15054.6 EST46169.1 - 0.14 11.9 0.4 6.5 6.6 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4535) DHHC PF01529.20 EST46169.1 - 0.18 11.9 17.9 0.02 15.0 6.7 2.9 1 1 1 2 2 2 0 DHHC palmitoyltransferase Zn-ribbon_8 PF09723.10 EST46170.1 - 0.002 18.2 0.5 0.0063 16.6 0.5 1.9 1 0 0 1 1 1 1 Zinc ribbon domain PhnA_Zn_Ribbon PF08274.12 EST46170.1 - 0.004 17.1 0.1 0.01 15.8 0.1 1.7 1 0 0 1 1 1 1 PhnA Zinc-Ribbon DNA_RNApol_7kD PF03604.13 EST46170.1 - 0.021 14.5 2.2 0.089 12.5 2.2 2.2 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.19 EST46170.1 - 0.035 14.1 0.1 0.13 12.3 0.1 2.0 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA NOB1_Zn_bind PF08772.11 EST46170.1 - 0.042 14.0 0.8 0.12 12.5 0.8 1.7 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like LIM PF00412.22 EST46170.1 - 0.064 13.5 2.0 0.15 12.3 2.0 1.6 1 0 0 1 1 1 0 LIM domain zinc_ribbon_10 PF10058.9 EST46170.1 - 0.066 13.0 0.3 0.19 11.5 0.3 1.8 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein ADK_lid PF05191.14 EST46170.1 - 0.071 13.1 0.2 0.13 12.3 0.2 1.5 1 0 0 1 1 1 0 Adenylate kinase, active site lid zinc_ribbon_4 PF13717.6 EST46170.1 - 0.12 12.4 1.9 0.29 11.1 1.9 1.7 1 0 0 1 1 1 0 zinc-ribbon domain Vps36-NZF-N PF16988.5 EST46170.1 - 0.2 11.1 0.1 0.2 11.1 0.1 2.0 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Gin PF10764.9 EST46170.1 - 2.8 8.0 6.1 22 5.1 0.2 3.4 2 1 1 3 3 3 0 Inhibitor of sigma-G Gin YjbF PF11102.8 EST46172.1 - 0.029 14.1 0.3 0.033 14.0 0.3 1.0 1 0 0 1 1 1 0 Group 4 capsule polysaccharide lipoprotein gfcB, YjbF PriX PF18689.1 EST46172.1 - 0.11 12.9 0.1 0.12 12.7 0.1 1.1 1 0 0 1 1 1 0 Primase X Herpes_UL36 PF03586.13 EST46173.1 - 9.4 5.5 7.1 4.1 6.6 0.2 3.1 3 0 0 3 3 3 0 Herpesvirus UL36 tegument protein HEAT_2 PF13646.6 EST46174.1 - 3e-07 30.7 0.0 0.00025 21.4 0.0 2.7 2 1 0 2 2 2 2 HEAT repeats PC_rep PF01851.22 EST46174.1 - 6.9e-06 26.2 8.4 0.023 15.1 0.2 6.2 7 0 0 7 7 7 2 Proteasome/cyclosome repeat Type_III_YscG PF09477.10 EST46174.1 - 0.087 12.9 0.2 4.5 7.4 0.1 2.7 2 0 0 2 2 2 0 Bacterial type II secretion system chaperone protein (type_III_yscG) Vac14_Fab1_bd PF12755.7 EST46174.1 - 0.093 13.3 2.3 0.74 10.5 0.0 3.4 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region HEAT PF02985.22 EST46174.1 - 0.14 12.5 0.0 9.5 6.8 0.0 2.9 2 0 0 2 2 2 0 HEAT repeat zf-RING_UBOX PF13445.6 EST46175.1 - 0.0096 15.9 0.5 0.0096 15.9 0.5 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EST46175.1 - 0.017 15.1 3.7 0.052 13.5 3.7 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_11 PF17123.5 EST46175.1 - 0.13 12.0 6.0 0.044 13.5 1.1 2.6 2 0 0 2 2 2 0 RING-like zinc finger PHD PF00628.29 EST46175.1 - 0.28 11.1 5.7 1.3 9.0 5.7 2.2 1 1 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.6 EST46175.1 - 4.8 7.6 11.0 1.6 9.1 6.0 2.7 2 1 0 2 2 2 0 Ring finger domain Prok-RING_1 PF14446.6 EST46175.1 - 7.9 6.5 7.2 0.37 10.8 0.2 2.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-rbx1 PF12678.7 EST46175.1 - 9.2 6.6 9.4 0.19 12.0 0.4 2.7 3 0 0 3 3 3 0 RING-H2 zinc finger domain zf-HIT PF04438.16 EST46176.1 - 0.0032 17.3 5.2 0.0072 16.2 5.2 1.6 1 0 0 1 1 1 1 HIT zinc finger H2TH PF06831.14 EST46177.1 - 3.7e-10 39.6 0.0 8.4e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Neil1-DNA_bind PF09292.10 EST46177.1 - 1e-05 25.4 1.0 3.5e-05 23.7 0.5 2.0 2 0 0 2 2 2 1 Endonuclease VIII-like 1, DNA bind Fapy_DNA_glyco PF01149.24 EST46177.1 - 0.00039 21.0 0.0 0.00065 20.3 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain Ribosomal_S13 PF00416.22 EST46177.1 - 0.029 14.8 0.3 0.99 9.8 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein S13/S18 GD_N PF16030.5 EST46177.1 - 0.039 14.3 0.5 0.089 13.1 0.5 1.6 1 0 0 1 1 1 0 Serine protease gd N-terminus Cytomega_US3 PF05963.11 EST46177.1 - 0.077 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Cytomegalovirus US3 protein Cornichon PF03311.14 EST46178.1 - 2.1e-07 31.3 6.2 3.3e-07 30.6 6.2 1.4 1 1 0 1 1 1 1 Cornichon protein DHHC PF01529.20 EST46179.1 - 3.2e-20 72.6 7.2 3.2e-20 72.6 7.2 2.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase Phage_antitermQ PF06530.12 EST46181.1 - 0.079 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Phage antitermination protein Q Cortexin PF11057.8 EST46181.1 - 1.9 8.4 4.0 3.7 7.5 2.1 2.2 2 1 0 2 2 2 0 Cortexin of kidney CENP-F_leu_zip PF10473.9 EST46184.1 - 3.2 7.8 41.8 0.078 13.0 24.4 3.1 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CdvA PF18822.1 EST46184.1 - 3.2 7.6 25.8 0.61 9.9 8.3 3.4 2 1 1 3 3 3 0 CdvA-like coiled-coil domain DUF2859 PF11072.8 EST46185.1 - 0.073 12.8 0.2 0.11 12.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2859) RTP1_C1 PF10363.9 EST46186.1 - 0.053 13.7 1.9 3.4 7.9 0.1 3.5 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 HECT PF00632.25 EST46187.1 - 4.8e-62 210.2 4.5 7.1e-62 209.6 4.5 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) NblA PF04485.12 EST46189.1 - 0.008 16.6 1.5 0.019 15.4 1.5 1.6 1 0 0 1 1 1 1 Phycobilisome degradation protein nblA RST PF12174.8 EST46189.1 - 0.018 14.9 0.4 0.018 14.9 0.4 1.8 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain DEAD PF00270.29 EST46192.1 - 6.9e-29 100.9 1.9 6.9e-29 100.9 1.9 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EST46192.1 - 4.3e-18 65.7 2.0 1e-17 64.5 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EST46192.1 - 7.8e-10 39.0 0.5 8e-09 35.7 0.5 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EST46192.1 - 0.00053 19.8 0.0 0.0029 17.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EST46192.1 - 0.0042 17.4 1.0 0.019 15.2 0.2 2.4 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 EST46192.1 - 0.0044 16.9 0.3 0.012 15.6 0.3 1.7 1 0 0 1 1 1 1 NACHT domain Helicase_RecD PF05127.14 EST46192.1 - 0.0066 16.3 0.2 0.019 14.8 0.0 1.8 2 0 0 2 2 2 1 Helicase AAA_11 PF13086.6 EST46192.1 - 0.014 15.2 7.7 0.2 11.4 0.1 3.0 2 1 1 3 3 3 0 AAA domain Flavi_DEAD PF07652.14 EST46192.1 - 0.014 15.3 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain PhoH PF02562.16 EST46192.1 - 0.014 14.8 0.1 0.049 13.1 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein UvrD-helicase PF00580.21 EST46192.1 - 2.2 7.7 9.4 27 4.2 9.4 2.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain Gly_acyl_tr_N PF06021.11 EST46192.1 - 4 7.5 8.4 0.61 10.2 0.1 2.7 2 2 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase Phage_sheath_1C PF17482.2 EST46194.1 - 0.047 13.7 0.1 0.064 13.2 0.1 1.3 1 1 0 1 1 1 0 Phage tail sheath C-terminal domain FlaC_arch PF05377.11 EST46195.1 - 0.43 11.0 6.4 3.4 8.1 0.4 4.1 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DEAD PF00270.29 EST46196.1 - 1.1e-45 155.5 0.3 2.6e-45 154.3 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EST46196.1 - 1.3e-30 106.0 0.7 4.1e-29 101.2 0.2 2.9 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EST46196.1 - 3.3e-06 27.2 0.0 3.3e-06 27.2 0.0 2.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 EST46196.1 - 0.0011 17.8 1.0 1.9 7.2 0.3 3.1 2 1 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ERCC3_RAD25_C PF16203.5 EST46196.1 - 0.0026 17.0 0.0 0.0044 16.2 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 EST46196.1 - 0.0093 15.3 0.1 0.026 13.9 0.0 1.8 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit SHIPPO-rpt PF07004.12 EST46197.1 - 0.0012 19.6 2.2 0.022 15.7 0.2 3.4 3 0 0 3 3 3 1 Sperm-tail PG-rich repeat Hexapep PF00132.24 EST46198.1 - 5.2e-07 29.1 4.7 0.00095 18.8 0.6 3.2 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 EST46198.1 - 1.1e-06 28.5 0.0 8.9e-06 25.5 0.0 2.5 1 1 0 1 1 1 1 Nucleotidyl transferase Fucokinase PF07959.12 EST46198.1 - 4.4e-05 22.6 0.3 4.4e-05 22.6 0.3 1.7 2 0 0 2 2 2 1 L-fucokinase Hexapep_2 PF14602.6 EST46198.1 - 0.0036 17.0 4.1 0.39 10.5 0.6 2.4 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Ribosomal_L36e PF01158.18 EST46199.1 - 2.1e-17 63.2 2.3 2.3e-17 63.0 2.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L36e NICE-3 PF07406.11 EST46200.1 - 0.043 13.8 0.0 0.052 13.5 0.0 1.1 1 0 0 1 1 1 0 NICE-3 protein Fimbrial PF00419.20 EST46200.1 - 0.11 12.7 0.3 0.14 12.4 0.3 1.1 1 0 0 1 1 1 0 Fimbrial protein DUF3159 PF11361.8 EST46200.1 - 0.25 11.1 0.0 0.31 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3159) Nop PF01798.18 EST46201.1 - 1.6e-60 204.4 0.4 1.6e-60 204.4 0.4 2.9 2 1 1 3 3 3 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EST46201.1 - 1.9 8.9 0.0 1.9 8.9 0.0 3.5 2 2 1 3 3 3 0 NOP5NT (NUC127) domain Trimer_CC PF08954.11 EST46202.1 - 0.0096 15.5 1.1 0.02 14.4 1.1 1.5 1 0 0 1 1 1 1 Trimerisation motif RNaseH_like PF04308.12 EST46202.1 - 0.045 13.7 0.2 0.091 12.7 0.2 1.6 1 0 0 1 1 1 0 Ribonuclease H-like TMF_TATA_bd PF12325.8 EST46202.1 - 0.5 10.6 11.9 0.4 10.9 2.1 2.8 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding ATP_bind_1 PF03029.17 EST46203.1 - 3.5e-43 148.1 0.3 4.1e-43 147.9 0.3 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein SRP54 PF00448.22 EST46203.1 - 4.6e-05 23.1 0.2 0.00027 20.6 0.1 2.0 2 1 0 2 2 2 1 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 EST46203.1 - 0.00012 21.4 0.0 0.0036 16.6 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 EST46203.1 - 0.00031 21.0 0.0 0.0013 19.0 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 EST46203.1 - 0.00034 21.2 0.0 0.00085 19.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EST46203.1 - 0.00075 19.3 0.0 0.0063 16.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EST46203.1 - 0.00096 19.4 0.0 0.0078 16.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 EST46203.1 - 0.0014 18.5 0.8 0.42 10.5 0.0 3.1 2 1 1 3 3 3 1 NTPase PduV-EutP PF10662.9 EST46203.1 - 0.0029 17.4 0.7 0.045 13.5 0.1 2.6 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 EST46203.1 - 0.0035 17.8 0.0 0.0048 17.4 0.0 1.4 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EST46203.1 - 0.0059 17.0 0.0 0.013 15.9 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 EST46203.1 - 0.006 16.6 0.1 0.021 14.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EST46203.1 - 0.006 16.5 0.3 1.3 8.9 0.0 3.4 2 1 2 4 4 4 1 RsgA GTPase AAA_31 PF13614.6 EST46203.1 - 0.009 15.9 0.5 1.1 9.2 0.2 2.6 2 1 0 2 2 1 1 AAA domain AAA PF00004.29 EST46203.1 - 0.009 16.4 0.0 0.025 15.0 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 EST46203.1 - 0.0091 15.9 0.0 0.08 12.8 0.0 2.1 2 0 0 2 2 2 1 Adenylylsulphate kinase ArsA_ATPase PF02374.15 EST46203.1 - 0.0092 15.2 0.0 0.023 13.9 0.0 1.6 2 0 0 2 2 2 1 Anion-transporting ATPase TsaE PF02367.17 EST46203.1 - 0.012 15.6 0.1 0.034 14.2 0.1 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CLP1_P PF16575.5 EST46203.1 - 0.019 14.8 0.0 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NACHT PF05729.12 EST46203.1 - 0.024 14.6 0.3 0.034 14.1 0.3 1.4 1 1 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.23 EST46203.1 - 0.027 14.6 0.1 0.36 10.9 0.1 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.19 EST46203.1 - 0.031 13.9 0.1 0.15 11.6 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 EST46203.1 - 0.033 13.9 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EST46203.1 - 0.035 14.5 0.0 0.087 13.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase CbiA PF01656.23 EST46203.1 - 0.035 14.1 0.0 0.04 14.0 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NB-ARC PF00931.22 EST46203.1 - 0.043 13.0 0.0 0.077 12.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.6 EST46203.1 - 0.048 13.8 0.0 0.12 12.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EST46203.1 - 0.051 13.0 0.1 0.11 11.9 0.0 1.6 2 0 0 2 2 1 0 PhoH-like protein MipZ PF09140.11 EST46203.1 - 0.075 12.3 0.0 0.19 11.0 0.0 1.7 1 1 1 2 2 2 0 ATPase MipZ PRK PF00485.18 EST46203.1 - 0.077 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_25 PF13481.6 EST46203.1 - 0.078 12.5 0.2 0.14 11.8 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EST46203.1 - 0.086 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) T2SSE PF00437.20 EST46203.1 - 0.091 11.8 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein CBP_BcsQ PF06564.12 EST46203.1 - 0.1 12.1 0.0 2.3 7.6 0.0 2.2 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ AAA_29 PF13555.6 EST46203.1 - 0.1 12.4 0.2 0.27 11.0 0.1 1.8 2 0 0 2 2 1 0 P-loop containing region of AAA domain DUF2075 PF09848.9 EST46203.1 - 0.11 11.7 0.1 0.16 11.2 0.1 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.6 EST46203.1 - 0.11 12.9 0.1 0.25 11.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EST46203.1 - 0.12 12.2 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain MeaB PF03308.16 EST46203.1 - 0.17 10.9 0.0 0.33 9.9 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATG16 PF08614.11 EST46204.1 - 0.0027 17.9 29.1 0.0027 17.9 29.1 2.3 2 1 0 2 2 2 1 Autophagy protein 16 (ATG16) Baculo_PEP_C PF04513.12 EST46204.1 - 0.019 15.0 11.1 0.019 15.0 11.1 3.2 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1298 PF06974.13 EST46204.1 - 0.14 12.1 2.6 11 6.0 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1298) Sas6_CC PF18594.1 EST46204.1 - 0.26 11.1 27.7 8.6 6.2 0.6 5.9 5 0 0 5 5 5 0 Sas6/XLF/XRCC4 coiled-coil domain Apolipoprotein PF01442.18 EST46204.1 - 1.5 8.7 30.0 2 8.3 28.3 2.0 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain HalX PF08663.10 EST46204.1 - 1.9 8.8 24.6 33 4.9 12.4 2.9 1 1 1 2 2 2 0 HalX domain Nas2_N PF18265.1 EST46204.1 - 2 8.4 12.5 4.6 7.2 1.0 3.8 1 1 4 5 5 5 0 Nas2 N_terminal domain Sec2p PF06428.11 EST46204.1 - 4.3 7.4 39.4 0.69 9.9 5.3 5.4 3 2 3 7 7 7 0 GDP/GTP exchange factor Sec2p FUSC PF04632.12 EST46204.1 - 6.3 5.2 15.2 9.2 4.7 15.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1298 PF06974.13 EST46205.1 - 1.8 8.5 8.4 25 4.8 0.4 3.5 1 1 3 4 4 4 0 Protein of unknown function (DUF1298) GGDEF_2 PF17853.1 EST46206.1 - 0.035 14.4 0.0 0.069 13.4 0.0 1.6 1 1 0 1 1 1 0 GGDEF-like domain NADH-UOR_E PF16514.5 EST46206.1 - 0.24 11.7 1.9 15 5.9 0.3 2.6 2 0 0 2 2 2 0 putative NADH-ubiquinone oxidoreductase chain E Vac_Fusion PF02346.16 EST46207.1 - 0.023 14.3 0.1 0.068 12.8 0.1 1.8 1 0 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 GDE_C PF06202.14 EST46208.1 - 1.9e-57 195.0 0.2 3.4e-57 194.1 0.2 1.4 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hDGE_amylase PF14701.6 EST46208.1 - 1.1e-34 120.4 11.7 1.1e-33 117.1 11.7 2.5 1 1 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain hGDE_central PF14702.6 EST46208.1 - 2.8e-11 43.6 0.0 6.9e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme HTH_ABP1_N PF18107.1 EST46208.1 - 0.8 9.5 2.8 14 5.4 0.1 3.1 3 0 0 3 3 3 0 Fission yeast centromere protein N-terminal domain ADP_PFK_GK PF04587.15 EST46211.1 - 1.5e-30 106.2 6.3 2.6e-29 102.0 2.2 2.1 1 1 1 2 2 2 2 ADP-specific Phosphofructokinase/Glucokinase conserved region ANAPC4_WD40 PF12894.7 EST46212.1 - 0.00028 21.1 0.1 4.5 7.6 0.0 4.2 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EST46212.1 - 0.00041 21.1 0.3 32 5.6 0.0 4.6 5 1 0 5 5 5 2 WD domain, G-beta repeat PQQ PF01011.21 EST46212.1 - 0.18 11.8 0.4 1e+02 3.1 0.0 3.9 5 0 0 5 5 5 0 PQQ enzyme repeat SUI1 PF01253.22 EST46213.1 - 2.1e-16 60.2 0.2 3.6e-16 59.5 0.2 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF4394 PF14339.6 EST46214.1 - 0.017 14.5 0.4 0.033 13.6 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4394) DUF3631 PF12307.8 EST46214.1 - 0.33 11.1 7.0 0.47 10.6 5.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3631) DSPc PF00782.20 EST46216.1 - 3.6e-18 65.6 0.0 4.1e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EST46216.1 - 0.0011 18.5 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Ribosomal_L22e PF01776.17 EST46217.1 - 3e-16 59.7 1.4 3.4e-16 59.6 1.4 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Big_5 PF13205.6 EST46217.1 - 0.015 15.9 0.3 0.019 15.7 0.3 1.1 1 0 0 1 1 1 0 Bacterial Ig-like domain DUF2281 PF10047.9 EST46217.1 - 0.061 14.0 0.1 8.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2281) Nse4-Nse3_bdg PF15412.6 EST46217.1 - 0.096 12.8 0.3 0.81 9.8 0.0 2.2 2 1 0 2 2 2 0 Binding domain of Nse4/EID3 to Nse3-MAGE JAB PF01398.21 EST46218.1 - 9e-29 99.8 0.3 1.3e-28 99.4 0.3 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 EST46218.1 - 2.9e-06 27.0 0.0 4.6e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain T4_Gp59_N PF08993.10 EST46220.1 - 0.78 10.2 4.2 0.55 10.7 0.1 2.7 2 1 1 3 3 3 0 T4 gene Gp59 loader of gp41 DNA helicase SNARE PF05739.19 EST46221.1 - 0.0035 17.3 0.3 0.012 15.6 0.0 2.1 2 0 0 2 2 2 1 SNARE domain Rhodanese PF00581.20 EST46222.1 - 2.4e-07 31.2 0.0 0.00034 21.1 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain BrkDBD PF09607.10 EST46223.1 - 3.2e-05 23.6 0.5 6.9e-05 22.5 0.5 1.6 1 0 0 1 1 1 1 Brinker DNA-binding domain HTH_23 PF13384.6 EST46223.1 - 0.036 13.9 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain NUMOD1 PF07453.13 EST46223.1 - 0.057 13.7 0.2 0.17 12.2 0.2 1.7 1 0 0 1 1 1 0 NUMOD1 domain MerR_1 PF13411.6 EST46223.1 - 0.12 12.5 0.1 0.22 11.6 0.1 1.6 1 1 0 1 1 1 0 MerR HTH family regulatory protein Homeodomain PF00046.29 EST46225.1 - 5.4e-08 32.6 0.2 1e-07 31.7 0.2 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EST46225.1 - 0.16 11.9 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Homeobox KN domain Ctf8 PF09696.10 EST46226.1 - 0.03 14.7 0.5 3.3 8.1 0.1 2.8 1 1 1 2 2 2 0 Ctf8 AMP-binding_C_2 PF14535.6 EST46227.1 - 0.11 12.8 0.9 0.38 11.1 0.2 1.9 1 1 1 2 2 2 0 AMP-binding enzyme C-terminal domain Ank_2 PF12796.7 EST46228.1 - 1.1e-08 35.5 0.0 4.9e-08 33.5 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EST46228.1 - 1.2e-08 35.3 0.1 0.00047 20.7 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EST46228.1 - 6.7e-07 29.5 0.0 0.00019 21.7 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EST46228.1 - 2.8e-06 27.2 0.0 6.5e-05 23.0 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 EST46228.1 - 0.00012 22.3 0.0 0.0018 18.6 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat zinc_ribbon_15 PF17032.5 EST46228.1 - 0.013 16.3 4.2 0.028 15.2 4.2 1.7 1 1 0 1 1 1 0 zinc-ribbon family zinc_ribbon_2 PF13240.6 EST46228.1 - 0.046 13.4 5.8 0.15 11.8 5.8 2.0 1 0 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 EST46228.1 - 0.083 12.3 3.4 0.22 11.0 3.4 1.7 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.7 EST46228.1 - 0.95 9.5 6.6 0.53 10.4 3.6 2.0 2 0 0 2 2 2 0 Double zinc ribbon WD40 PF00400.32 EST46229.1 - 1.1e-05 26.1 0.5 0.037 14.9 0.1 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF916 PF06030.12 EST46229.1 - 0.026 14.6 0.5 0.086 12.9 0.1 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF916) COesterase PF00135.28 EST46231.1 - 0.032 13.1 1.4 0.043 12.7 1.4 1.1 1 0 0 1 1 1 0 Carboxylesterase family Acyltransferase PF01553.21 EST46233.1 - 0.0004 20.0 0.0 0.00078 19.1 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase SpoU_methylas_C PF12105.8 EST46233.1 - 0.03 14.0 0.1 0.071 12.8 0.1 1.6 1 0 0 1 1 1 0 SpoU, rRNA methylase, C-terminal TRP PF06011.12 EST46233.1 - 0.057 12.1 2.3 0.094 11.4 2.3 1.2 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Anoctamin PF04547.12 EST46233.1 - 0.11 11.4 1.2 0.2 10.5 1.2 1.4 1 0 0 1 1 1 0 Calcium-activated chloride channel Proteasome PF00227.26 EST46235.1 - 9.1e-15 54.6 0.1 1.2e-14 54.3 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EST46235.1 - 1e-10 41.1 0.1 1.8e-10 40.3 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Thyroglobulin_1 PF00086.18 EST46235.1 - 0.084 12.6 0.1 1.1 8.9 0.2 2.2 2 0 0 2 2 2 0 Thyroglobulin type-1 repeat Nuc_recep-AF1 PF11825.8 EST46235.1 - 0.12 12.5 2.0 0.15 12.1 1.2 1.5 1 1 0 1 1 1 0 Nuclear/hormone receptor activator site AF-1 LptF_LptG PF03739.14 EST46236.1 - 5.2 5.8 6.6 7.1 5.4 6.6 1.2 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG WD40_like PF17005.5 EST46237.1 - 2.9e-06 26.9 2.6 2.9e-06 26.9 2.6 2.5 2 1 0 2 2 2 1 WD40-like domain DAGK_cat PF00781.24 EST46237.1 - 0.032 13.9 0.2 0.088 12.4 0.0 1.8 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain APG12 PF04110.13 EST46237.1 - 0.07 13.5 0.1 0.07 13.5 0.1 2.3 2 1 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 ANAPC4_WD40 PF12894.7 EST46237.1 - 0.08 13.3 0.0 28 5.1 0.0 4.0 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain SMC_N PF02463.19 EST46238.1 - 7.5e-22 77.8 1.3 1.7e-11 44.0 0.2 2.9 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EST46238.1 - 1.8e-18 67.8 11.5 1.8e-18 67.8 11.5 6.6 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.6 EST46238.1 - 3.8e-08 33.5 3.3 1.5e-06 28.3 0.1 3.7 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EST46238.1 - 2.9e-05 23.7 0.0 7.8e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_27 PF13514.6 EST46238.1 - 0.00026 20.7 0.9 0.0012 18.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EST46238.1 - 0.0072 16.7 0.9 0.056 13.8 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 EST46238.1 - 0.0074 16.8 0.2 0.0074 16.8 0.2 5.5 3 3 0 3 3 3 1 ABC transporter GlcNAc-1_reg PF18440.1 EST46238.1 - 10 6.5 7.8 24 5.2 0.1 4.6 3 1 1 4 4 4 0 Putative GlcNAc-1 phosphotransferase regulatory domain CKAP2_C PF15297.6 EST46240.1 - 0.0034 16.5 0.2 0.0044 16.2 0.2 1.1 1 0 0 1 1 1 1 Cytoskeleton-associated protein 2 C-terminus SPACA9 PF15120.6 EST46240.1 - 0.051 13.4 0.4 0.1 12.3 0.4 1.7 1 1 0 1 1 1 0 Sperm acrosome-associated protein 9 HAD_2 PF13419.6 EST46241.1 - 1.6e-24 86.9 0.0 2.7e-24 86.2 0.0 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EST46241.1 - 4.2e-10 40.3 0.0 5.5e-09 36.6 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EST46241.1 - 9.5e-06 26.1 0.0 1.5e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EST46241.1 - 0.004 17.2 0.0 0.58 10.3 0.0 2.4 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EST46241.1 - 0.051 13.7 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like VasI PF11319.8 EST46241.1 - 0.074 12.7 0.0 0.35 10.5 0.0 1.9 2 0 0 2 2 2 0 Type VI secretion system VasI, EvfG, VC_A0118 14-3-3 PF00244.20 EST46244.1 - 6e-95 317.0 6.0 6.8e-95 316.8 6.0 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.6 EST46244.1 - 0.03 14.6 1.5 6.1 7.2 0.5 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat HBM PF16591.5 EST46244.1 - 0.18 11.2 3.9 0.15 11.4 1.5 2.1 2 1 0 2 2 2 0 Helical bimodular sensor domain TPR_8 PF13181.6 EST46244.1 - 1.2 9.5 7.2 7 7.1 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat CENP-F_leu_zip PF10473.9 EST46245.1 - 0.066 13.2 26.3 0.044 13.8 5.0 3.2 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PolyA_pol PF01743.20 EST46245.1 - 0.31 11.5 6.2 0.059 13.8 1.5 2.2 2 1 1 3 3 3 0 Poly A polymerase head domain DUF3292 PF11696.8 EST46245.1 - 0.39 9.0 12.9 0.0062 15.0 2.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3292) Lebercilin PF15619.6 EST46245.1 - 0.54 9.9 38.6 0.39 10.3 5.1 4.1 3 1 1 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease TMF_DNA_bd PF12329.8 EST46245.1 - 0.9 9.6 31.0 1.3 9.1 5.1 3.4 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding WAC_Acf1_DNA_bd PF10537.9 EST46245.1 - 3 8.4 9.4 1.3 9.6 0.3 3.0 3 0 0 3 3 3 0 ATP-utilising chromatin assembly and remodelling N-terminal TMF_TATA_bd PF12325.8 EST46245.1 - 4.4 7.6 29.7 1.1 9.6 5.0 4.2 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding Filament PF00038.21 EST46245.1 - 4.9 6.6 37.0 4.7 6.7 22.7 3.0 1 1 1 2 2 2 0 Intermediate filament protein Gar1 PF04410.14 EST46246.1 - 3.6e-08 33.3 0.0 4.7e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region DHHC PF01529.20 EST46247.1 - 2e-32 112.1 16.1 2e-32 112.1 16.1 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase Spt4 PF06093.13 EST46247.1 - 0.052 13.6 5.4 0.11 12.7 5.4 1.5 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger Sugar_tr PF00083.24 EST46248.1 - 1e-13 51.0 28.8 6.6e-10 38.4 11.8 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter DUF2070 PF09843.9 EST46249.1 - 1.2 7.3 17.2 1.5 7.1 17.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF2205 PF10224.9 EST46251.1 - 0.016 15.1 0.8 0.016 15.1 0.8 2.2 1 1 1 2 2 2 0 Short coiled-coil protein Erf4 PF10256.9 EST46251.1 - 0.045 13.9 0.1 0.066 13.3 0.1 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family DUF3023 PF11224.8 EST46251.1 - 0.23 11.3 2.5 0.3 10.9 0.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3023) Fzo_mitofusin PF04799.13 EST46251.1 - 0.33 10.5 3.8 0.49 9.9 3.8 1.3 1 0 0 1 1 1 0 fzo-like conserved region Chibby PF14645.6 EST46251.1 - 0.42 11.0 5.2 1.1 9.7 5.2 1.7 1 1 0 1 1 1 0 Chibby family bZIP_2 PF07716.15 EST46251.1 - 1 9.5 3.6 12 6.1 0.1 2.4 2 0 0 2 2 2 0 Basic region leucine zipper DivIC PF04977.15 EST46251.1 - 2 8.2 5.3 19 5.1 0.2 2.3 1 1 1 2 2 2 0 Septum formation initiator RhoGAP PF00620.27 EST46252.1 - 1.8e-19 70.1 0.9 3.6e-19 69.1 0.9 1.5 1 0 0 1 1 1 1 RhoGAP domain ApoC-I PF04691.12 EST46252.1 - 0.36 10.8 10.3 1.4 8.9 1.1 3.4 1 1 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) YtxH PF12732.7 EST46252.1 - 0.37 11.4 2.9 1.7 9.2 3.0 2.1 1 1 0 1 1 1 0 YtxH-like protein zf-RING_4 PF14570.6 EST46253.1 - 5.3e-05 22.9 21.1 5.3e-05 22.9 21.1 1.9 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain HSP70 PF00012.20 EST46254.1 - 1.2e-239 796.5 13.8 1.4e-239 796.3 13.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EST46254.1 - 1e-15 57.4 0.1 1.6e-13 50.2 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein DUF2336 PF10098.9 EST46254.1 - 0.18 11.3 0.8 0.43 10.0 0.8 1.6 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2336) CdiA_C PF18451.1 EST46254.1 - 1.4 9.2 12.4 0.072 13.3 1.3 3.7 3 1 0 3 3 3 0 Contact-dependent growth inhibition CdiA C-terminal domain ALMT PF11744.8 EST46254.1 - 6 5.6 7.6 11 4.7 7.6 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter ACP53EA PF06313.11 EST46256.1 - 0.059 13.6 1.6 0.14 12.4 0.2 2.1 2 1 0 2 2 2 0 Drosophila ACP53EA protein Ski_Sno PF02437.17 EST46257.1 - 0.026 14.3 12.9 0.069 12.9 1.3 5.0 5 0 0 5 5 5 0 SKI/SNO/DAC family Lip_prot_lig_C PF10437.9 EST46257.1 - 0.03 14.3 0.7 0.7 9.9 0.0 3.3 3 1 1 4 4 4 0 Bacterial lipoate protein ligase C-terminus LRR_4 PF12799.7 EST46260.1 - 0.00013 22.3 13.3 0.41 11.1 0.0 7.1 7 2 1 8 8 8 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EST46260.1 - 0.22 11.3 9.8 6.2 6.7 0.2 5.2 4 1 0 4 4 4 0 Leucine rich repeat HXXSHH PF07586.11 EST46263.1 - 0.11 12.0 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) LRR_4 PF12799.7 EST46264.1 - 8.4e-05 22.9 13.0 1.4 9.4 0.1 6.9 7 1 1 8 8 8 4 Leucine Rich repeats (2 copies) PAS_7 PF12860.7 EST46265.1 - 0.022 14.9 0.0 0.045 13.9 0.0 1.5 1 0 0 1 1 1 0 PAS fold DUF3251 PF11622.8 EST46265.1 - 0.08 12.6 0.4 0.12 12.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) DUF3090 PF11290.8 EST46267.1 - 0.057 13.2 0.2 0.89 9.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3090) Sulfatase PF00884.23 EST46269.1 - 6e-15 55.4 1.3 7.7e-15 55.1 1.3 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EST46269.1 - 0.02 14.5 4.0 0.19 11.3 0.1 2.3 1 1 1 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase LRRFIP PF09738.9 EST46273.1 - 0.00098 18.7 6.2 0.0014 18.2 6.2 1.2 1 0 0 1 1 1 1 LRRFIP family BpuSI_N PF15516.6 EST46273.1 - 0.04 13.8 0.1 0.04 13.8 0.1 2.4 2 1 0 2 2 2 0 BpuSI N-terminal domain DUF445 PF04286.12 EST46273.1 - 0.28 10.9 7.0 0.36 10.6 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF295 PF03478.18 EST46274.1 - 0.00088 18.8 0.3 0.88 9.2 0.2 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF295) RNA_helicase PF00910.22 EST46275.1 - 0.0077 16.6 2.1 0.83 10.1 0.3 2.7 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.6 EST46275.1 - 0.012 15.8 0.1 0.029 14.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EST46275.1 - 0.014 15.9 0.3 0.028 14.9 0.3 1.6 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 EST46275.1 - 0.068 13.4 0.2 0.58 10.4 0.0 2.2 1 1 0 2 2 2 0 AAA domain Myosin-VI_CBD PF16521.5 EST46275.1 - 0.088 12.8 1.9 4.3 7.4 0.3 2.9 1 1 2 3 3 3 0 Myosin VI cargo binding domain AAA_17 PF13207.6 EST46275.1 - 0.095 13.1 0.1 0.34 11.3 0.0 1.9 1 1 1 2 2 2 0 AAA domain DSPc PF00782.20 EST46275.1 - 0.46 10.3 4.9 0.39 10.5 2.6 2.0 1 1 1 2 2 2 0 Dual specificity phosphatase, catalytic domain Rit1_C PF17184.4 EST46279.1 - 0.047 13.1 0.9 0.049 13.1 0.9 1.2 1 0 0 1 1 1 0 Rit1 N-terminal domain Mucin_bdg PF03272.13 EST46279.1 - 0.068 13.2 0.6 0.1 12.6 0.6 1.4 1 0 0 1 1 1 0 Putative mucin or carbohydrate-binding module RRM_1 PF00076.22 EST46280.1 - 0.00062 19.5 0.3 0.31 10.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TRM13 PF05206.14 EST46282.1 - 1.2e-28 100.3 2.1 1.7e-20 73.7 0.9 2.2 1 1 1 2 2 2 2 Methyltransferase TRM13 Methyltransf_32 PF13679.6 EST46282.1 - 0.00024 21.1 0.5 0.00043 20.3 0.5 1.3 1 0 0 1 1 1 1 Methyltransferase domain zf-U11-48K PF05253.12 EST46282.1 - 0.00027 20.8 1.5 0.00061 19.7 1.5 1.7 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger Filo_VP35 PF02097.15 EST46283.1 - 4.4e-05 22.7 0.5 0.00014 21.0 0.5 1.8 1 0 0 1 1 1 1 Filoviridae VP35 RNA_helicase PF00910.22 EST46283.1 - 0.011 16.1 2.5 0.73 10.2 0.0 4.4 3 0 0 3 3 3 0 RNA helicase Pullulanase_Ins PF18494.1 EST46283.1 - 0.061 13.8 3.9 0.2 12.2 1.6 3.4 2 0 0 2 2 2 0 Pullulanase Ins domain AAA PF00004.29 EST46283.1 - 0.064 13.7 1.5 39 4.7 0.0 4.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) VPS13_mid_rpt PF16910.5 EST46284.1 - 0.0017 17.9 0.1 0.0029 17.1 0.1 1.4 1 0 0 1 1 1 1 Repeating coiled region of VPS13 RNA_pol_Rpb1_5 PF04998.17 EST46285.1 - 1.6e-75 254.0 11.9 1.9e-74 250.5 11.9 2.4 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EST46285.1 - 1.6e-59 200.9 0.0 5.5e-59 199.1 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 EST46285.1 - 1e-28 100.6 7.6 1e-28 100.6 7.6 2.6 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 EST46285.1 - 1.3e-22 80.4 0.6 8.9e-22 77.7 0.1 2.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EST46285.1 - 1.3e-14 54.1 0.0 1.3e-14 54.1 0.0 3.9 4 0 0 4 4 4 1 RNA polymerase Rpb1, domain 4 DUF3492 PF11997.8 EST46286.1 - 0.19 11.4 0.8 0.4 10.4 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3492) Gly_acyl_tr_C PF08444.10 EST46286.1 - 1.3 9.3 5.4 0.39 11.0 0.3 2.7 3 0 0 3 3 3 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Myb_DNA-binding PF00249.31 EST46287.1 - 1.1e-08 35.1 0.2 2.2e-08 34.2 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST46287.1 - 3.8e-06 27.0 2.8 4.5e-06 26.8 0.2 2.1 1 1 1 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST46287.1 - 0.00032 20.5 1.3 0.00058 19.7 1.3 1.6 1 1 0 1 1 1 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EST46287.1 - 0.00051 20.2 0.3 0.00093 19.4 0.3 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DUF3453 PF11935.8 EST46287.1 - 0.026 14.2 0.3 0.033 13.8 0.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3453) NAPRTase_N PF17767.1 EST46288.1 - 1.5e-33 115.8 0.2 3e-33 114.9 0.2 1.5 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase_C PF17956.1 EST46288.1 - 5.1e-27 94.5 0.1 1.1e-26 93.4 0.1 1.6 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase C-terminal domain NAPRTase PF04095.16 EST46288.1 - 6.9e-07 29.1 0.2 0.0042 16.7 0.0 2.2 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family Ribosomal_L24e PF01246.20 EST46289.1 - 7.2e-22 77.4 0.1 9.7e-22 77.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L24e DuoxA PF10204.9 EST46289.1 - 0.17 10.9 0.1 0.17 10.9 0.1 1.0 1 0 0 1 1 1 0 Dual oxidase maturation factor Ribosomal_S17e PF00833.18 EST46290.1 - 6.5e-41 139.1 4.2 7e-41 139.0 4.2 1.0 1 0 0 1 1 1 1 Ribosomal S17 LisH PF08513.11 EST46291.1 - 2.8e-09 36.6 3.1 6.2e-09 35.5 3.1 1.6 1 0 0 1 1 1 1 LisH DUF678 PF05077.12 EST46292.1 - 0.092 12.9 0.0 0.33 11.1 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF678) DnaB_bind PF10410.9 EST46292.1 - 0.096 12.9 0.0 1.1 9.6 0.0 2.7 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase DUF4407 PF14362.6 EST46292.1 - 0.46 9.8 4.7 1.2 8.4 4.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DNA_pol_B PF00136.21 EST46293.1 - 1.5e-54 185.4 15.8 9.3e-52 176.3 7.5 3.4 3 0 0 3 3 3 2 DNA polymerase family B zf-C4pol PF14260.6 EST46293.1 - 3.6e-07 30.5 14.5 1.9e-06 28.3 14.5 2.4 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DUF1016_N PF17761.1 EST46294.1 - 0.028 14.6 0.7 0.054 13.7 0.7 1.5 1 0 0 1 1 1 0 DUF1016 N-terminal domain Blo-t-5 PF11642.8 EST46294.1 - 0.18 11.8 5.0 0.33 10.9 1.1 2.5 2 1 1 3 3 3 0 Mite allergen Blo t 5 LRR_4 PF12799.7 EST46295.1 - 0.071 13.6 12.5 0.48 10.9 4.2 3.7 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EST46295.1 - 0.14 11.9 4.3 0.88 9.4 1.3 3.1 1 1 2 3 3 3 0 Leucine rich repeat JAKMIP_CC3 PF16034.5 EST46297.1 - 0.051 13.5 0.3 0.056 13.4 0.3 1.2 1 0 0 1 1 1 0 JAKMIP CC3 domain DUF5137 PF17220.3 EST46298.1 - 0.32 11.9 6.6 0.34 11.8 5.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF5137) Pkinase PF00069.25 EST46299.1 - 2.1e-16 60.1 1.2 4.9e-16 58.9 1.2 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST46299.1 - 1.5e-06 27.7 1.0 1.9e-06 27.4 0.3 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EST46299.1 - 0.00021 21.3 0.1 0.00053 20.0 0.3 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EST46299.1 - 0.0082 15.8 0.9 0.0082 15.8 0.9 2.3 3 0 0 3 3 3 1 RIO1 family Pox_M2 PF04887.12 EST46299.1 - 0.018 14.5 2.8 0.019 14.5 0.3 2.2 2 0 0 2 2 2 0 Poxvirus M2 protein UPF0181 PF03701.14 EST46299.1 - 0.024 14.2 1.4 0.059 13.0 1.4 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0181) Kdo PF06293.14 EST46299.1 - 1.7 8.0 5.7 6.8 6.0 1.2 2.7 2 1 1 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIH_assoc PF08454.11 EST46300.1 - 0.11 12.4 3.4 0.21 11.5 3.4 1.7 1 1 0 1 1 1 0 RyR and IP3R Homology associated DUF4407 PF14362.6 EST46301.1 - 3.3 7.0 9.4 4.7 6.5 9.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF223 PF02721.14 EST46302.1 - 0.54 10.6 5.2 9.5 6.6 0.3 2.9 2 1 0 2 2 2 0 Domain of unknown function DUF223 Chromo PF00385.24 EST46303.1 - 0.0012 18.7 1.4 0.0033 17.3 1.4 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Phage_int_SAM_5 PF13102.6 EST46303.1 - 0.007 16.7 1.8 0.022 15.1 1.9 1.9 1 1 0 1 1 1 1 Phage integrase SAM-like domain CH_2 PF06294.11 EST46304.1 - 1.9e-10 40.7 0.6 1.9e-10 40.7 0.6 2.2 2 0 0 2 2 2 1 CH-like domain in sperm protein DUF5311 PF17238.2 EST46304.1 - 0.0029 17.6 0.1 0.0086 16.0 0.1 1.8 1 0 0 1 1 1 1 Family of unknown function (DUF5311) TRAP-gamma PF07074.12 EST46304.1 - 0.62 9.6 4.7 0.11 12.1 0.3 2.0 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF498 PF04430.14 EST46305.1 - 0.084 12.9 0.0 0.17 11.9 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) DUF4428 PF14471.6 EST46305.1 - 0.18 11.7 4.0 0.72 9.8 1.7 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4428) YtzH PF14165.6 EST46306.1 - 0.072 13.5 0.1 0.13 12.6 0.1 1.4 1 0 0 1 1 1 0 YtzH-like protein Acetyltransf_1 PF00583.25 EST46308.1 - 3.9e-08 33.5 0.1 5e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EST46308.1 - 0.044 13.7 0.5 0.062 13.2 0.5 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Pkinase PF00069.25 EST46309.1 - 4.9e-38 131.0 1.8 1.8e-37 129.2 0.0 2.7 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST46309.1 - 1.3e-19 70.5 0.0 3.6e-19 69.1 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase PRCC PF10253.9 EST46309.1 - 0.22 12.3 3.5 0.38 11.5 3.5 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Bep_C_terminal PF17841.1 EST46310.1 - 3.3 8.0 10.6 2.4 8.5 1.8 3.6 2 0 0 2 2 2 0 BID domain of Bartonella effector protein (Bep) Pkinase PF00069.25 EST46311.1 - 2.7e-70 236.8 0.5 6.4e-70 235.5 0.5 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST46311.1 - 7.4e-42 143.4 0.2 1.4e-41 142.5 0.2 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EST46311.1 - 3.2e-07 30.0 0.1 2e-05 24.1 0.0 2.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EST46311.1 - 0.00074 18.9 0.1 0.0019 17.6 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EST46311.1 - 0.011 14.6 0.0 0.021 13.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EST46311.1 - 0.19 11.7 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family LRR_9 PF14580.6 EST46312.1 - 1.1e-06 28.3 1.1 1.1e-06 28.3 1.1 2.1 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 EST46312.1 - 6.2e-06 26.5 7.5 0.004 17.5 1.6 3.2 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EST46312.1 - 0.004 16.9 6.5 0.004 16.9 6.5 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 EST46312.1 - 0.036 14.1 2.5 8 6.8 0.2 3.3 3 0 0 3 3 3 0 Leucine Rich repeat MuF_C PF18819.1 EST46312.1 - 0.051 13.6 0.2 0.62 10.1 0.1 2.3 2 0 0 2 2 2 0 Phage MuF-C-terminal domain LRR_1 PF00560.33 EST46312.1 - 0.27 11.9 2.3 27 5.8 0.1 3.9 3 1 0 3 3 3 0 Leucine Rich Repeat FAM70 PF14967.6 EST46312.1 - 7 6.0 6.7 10 5.5 6.7 1.3 1 0 0 1 1 1 0 FAM70 protein UQ_con PF00179.26 EST46313.1 - 1.5e-29 102.5 0.1 1.8e-29 102.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EST46313.1 - 0.0054 16.4 0.0 0.0068 16.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B DUF1488 PF07369.11 EST46313.1 - 0.056 13.4 0.1 0.1 12.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1488) zf-C2H2_jaz PF12171.8 EST46314.1 - 2.8e-05 24.3 2.0 5.8e-05 23.3 0.4 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EST46314.1 - 6.2e-05 23.3 0.8 0.00048 20.4 0.5 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EST46314.1 - 0.0049 17.2 0.8 0.0049 17.2 0.8 1.9 2 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-RRPl_C4 PF17026.5 EST46314.1 - 0.007 16.4 0.1 0.016 15.3 0.1 1.7 1 0 0 1 1 1 1 Putative ribonucleoprotein zinc-finger pf C4 type CG-1 PF03859.16 EST46314.1 - 0.049 13.4 2.9 0.11 12.2 2.9 1.6 1 0 0 1 1 1 0 CG-1 domain zf-U1 PF06220.12 EST46314.1 - 0.1 12.4 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 U1 zinc finger RNase_T PF00929.24 EST46315.1 - 4.4e-12 46.8 0.3 1.4e-11 45.2 0.1 1.8 1 1 1 2 2 2 1 Exonuclease RVT_1 PF00078.27 EST46319.1 - 2.1e-23 83.0 0.0 3.4e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2 PF00096.26 EST46319.1 - 0.017 15.6 3.5 2.2 8.9 0.4 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type LSM PF01423.22 EST46321.1 - 6.5e-12 45.0 0.3 8.1e-12 44.7 0.3 1.1 1 0 0 1 1 1 1 LSM domain LD_cluster3 PF18180.1 EST46324.1 - 0.073 12.7 0.2 2.7 7.6 0.1 2.4 2 0 0 2 2 2 0 SLOG cluster3 family TMEM52 PF14979.6 EST46324.1 - 0.81 9.6 4.9 1.1e+02 2.7 0.0 2.6 2 0 0 2 2 2 0 Transmembrane 52 Myb_DNA-bind_6 PF13921.6 EST46326.1 - 0.0018 18.5 0.5 0.0018 18.5 0.5 1.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain CbiG_mid PF11761.8 EST46326.1 - 0.12 12.5 0.1 0.17 12.1 0.1 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis central region CaATP_NAI PF12515.8 EST46327.1 - 0.22 11.2 2.5 0.74 9.5 2.1 2.1 2 0 0 2 2 2 0 Ca2+-ATPase N terminal autoinhibitory domain Mem_trans PF03547.18 EST46332.1 - 2.3e-10 39.5 24.2 2.3e-06 26.3 9.5 2.0 1 1 1 2 2 2 2 Membrane transport protein DUF3989 PF13150.6 EST46332.1 - 0.21 11.3 0.1 0.21 11.3 0.1 2.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3989) DUF5527 PF17665.1 EST46332.1 - 4.8 6.7 8.2 0.43 10.1 0.4 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5527) DUF3552 PF12072.8 EST46333.1 - 0.0047 16.4 14.9 0.0047 16.4 14.9 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3552) Spc7 PF08317.11 EST46333.1 - 0.0051 15.7 9.9 0.0087 15.0 9.9 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein OmpH PF03938.14 EST46333.1 - 0.0078 16.6 14.6 0.0078 16.6 14.6 1.7 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) CEP209_CC5 PF16574.5 EST46333.1 - 0.0081 16.3 10.2 0.014 15.6 10.2 1.4 1 0 0 1 1 1 1 Coiled-coil region of centrosome protein CE290 G10 PF01125.17 EST46333.1 - 0.042 13.6 2.0 2.6 7.8 0.5 2.3 2 0 0 2 2 2 0 G10 protein Sipho_Gp157 PF05565.11 EST46333.1 - 0.19 11.8 9.6 5.6 7.0 7.9 2.3 2 1 0 2 2 2 0 Siphovirus Gp157 Exonuc_VII_L PF02601.15 EST46333.1 - 0.19 11.3 9.4 0.2 11.2 9.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 EST46333.1 - 0.31 8.9 5.1 0.36 8.7 5.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMPIT PF07851.13 EST46333.1 - 0.43 9.8 7.6 0.6 9.3 7.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF812 PF05667.11 EST46333.1 - 0.45 9.3 17.2 0.15 10.9 15.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF812) BRE1 PF08647.11 EST46333.1 - 0.51 10.4 16.9 0.029 14.4 11.4 1.8 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase ANAPC15 PF15243.6 EST46333.1 - 0.58 10.6 13.4 0.47 10.9 6.5 2.9 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 15 FapA PF03961.13 EST46333.1 - 0.98 8.0 8.4 1.5 7.3 8.4 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A HYLS1_C PF15311.6 EST46334.1 - 0.00043 21.0 0.9 0.00043 21.0 0.9 3.4 3 1 1 4 4 4 2 Hydrolethalus syndrome protein 1 C-terminus YsaB PF13983.6 EST46335.1 - 0.028 14.7 0.7 0.1 12.9 0.5 2.0 2 0 0 2 2 2 0 YsaB-like lipoprotein Exonuc_VII_L PF02601.15 EST46335.1 - 0.09 12.3 6.7 0.16 11.5 6.7 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit ALMT PF11744.8 EST46335.1 - 0.44 9.3 5.6 0.82 8.4 5.6 1.5 1 0 0 1 1 1 0 Aluminium activated malate transporter FAM195 PF14799.6 EST46335.1 - 0.56 10.6 13.5 0.049 14.0 6.2 2.7 3 1 0 3 3 3 0 FAM195 family DUF2937 PF11157.8 EST46335.1 - 4 7.1 7.0 12 5.6 4.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Peptidase_C10 PF01640.17 EST46335.1 - 9.8 6.4 7.4 21 5.3 7.4 1.5 1 0 0 1 1 1 0 Peptidase C10 family Ras PF00071.22 EST46336.1 - 1.7e-58 196.8 1.0 2e-58 196.6 1.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EST46336.1 - 5.3e-22 78.3 0.0 9e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EST46336.1 - 4.5e-12 45.8 0.1 5.2e-12 45.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EST46336.1 - 5.2e-08 32.6 0.5 1.5e-07 31.2 0.2 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EST46336.1 - 4.3e-07 30.0 1.7 0.00019 21.4 0.2 2.2 2 0 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 EST46336.1 - 3.8e-05 23.6 0.2 3.8e-05 23.6 0.2 1.8 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 EST46336.1 - 0.00014 21.9 0.0 0.00026 21.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EST46336.1 - 0.0065 16.0 1.5 0.017 14.7 0.1 2.1 2 1 0 2 2 2 1 Ferrous iron transport protein B Ser_hydrolase PF06821.13 EST46336.1 - 0.048 13.5 0.0 0.067 13.0 0.0 1.1 1 0 0 1 1 1 0 Serine hydrolase FixO PF02433.15 EST46338.1 - 0.031 13.7 0.3 0.041 13.3 0.3 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO Pkinase PF00069.25 EST46340.1 - 3.9e-43 147.7 0.0 6.2e-43 147.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST46340.1 - 3.6e-27 95.3 0.0 5.4e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EST46340.1 - 0.013 15.1 0.5 0.028 14.0 0.5 1.5 1 1 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 EST46340.1 - 0.037 12.8 0.0 0.079 11.7 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase Mto2_bdg PF12808.7 EST46340.1 - 0.096 13.0 0.1 0.096 13.0 0.1 2.8 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Leu_zip PF15294.6 EST46340.1 - 0.81 9.2 8.5 0.5 9.8 5.7 2.0 2 1 0 2 2 2 0 Leucine zipper TetR_C_24 PF17932.1 EST46342.1 - 0.0081 16.4 1.9 0.01 16.1 0.7 1.7 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain Cgr1 PF03879.14 EST46342.1 - 0.72 10.2 11.0 1.1 9.7 11.0 1.4 1 1 0 1 1 1 0 Cgr1 family Aminotran_1_2 PF00155.21 EST46343.1 - 8.2e-31 107.5 0.0 1e-30 107.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EST46343.1 - 0.024 13.9 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Polysacc_deac_2 PF04748.13 EST46343.1 - 0.1 11.7 0.0 0.22 10.7 0.0 1.5 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase SHIPPO-rpt PF07004.12 EST46344.1 - 1.1e-10 41.9 31.2 0.11 13.5 0.6 6.6 6 1 0 6 6 6 5 Sperm-tail PG-rich repeat LRR_6 PF13516.6 EST46347.1 - 3.9e-08 32.7 27.3 0.0087 16.0 0.1 6.6 6 0 0 6 6 6 4 Leucine Rich repeat LRR_4 PF12799.7 EST46347.1 - 1.8e-07 31.3 33.1 0.0019 18.5 1.7 5.6 2 2 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EST46347.1 - 1.1e-06 28.3 28.3 0.0005 19.8 4.3 5.1 1 1 4 5 5 5 4 Leucine rich repeat LRR_1 PF00560.33 EST46347.1 - 0.029 14.9 19.1 5.1 8.1 0.5 6.3 4 2 2 6 6 6 0 Leucine Rich Repeat Gal4_dimer PF03902.13 EST46347.1 - 6.3 7.0 6.4 10 6.4 1.2 3.2 3 0 0 3 3 3 0 Gal4-like dimerisation domain Pro_sub2 PF18513.1 EST46349.1 - 0.0026 17.9 3.7 0.22 11.7 0.4 3.4 2 0 0 2 2 2 2 Prodomain subtilisin 2 HI0933_like PF03486.14 EST46349.1 - 0.018 13.8 4.0 0.04 12.6 4.0 1.5 1 0 0 1 1 1 0 HI0933-like protein DUF2382 PF09557.10 EST46349.1 - 4.8 7.5 12.8 0.61 10.4 8.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2382) Fzo_mitofusin PF04799.13 EST46350.1 - 0.12 11.9 3.3 0.18 11.3 3.3 1.2 1 0 0 1 1 1 0 fzo-like conserved region Peptidase_M18 PF02127.15 EST46352.1 - 1e-40 139.9 0.0 1.3e-40 139.6 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) CBM46 PF18448.1 EST46352.1 - 0.048 14.0 0.0 0.21 11.9 0.0 1.9 2 0 0 2 2 2 0 Carbohydrate binding domain IP_trans PF02121.18 EST46355.1 - 9.9e-19 67.9 6.7 1e-17 64.5 6.7 1.9 1 1 0 1 1 1 1 Phosphatidylinositol transfer protein TBPIP PF07106.13 EST46355.1 - 0.0028 17.6 0.4 0.0066 16.4 0.4 1.8 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain DUF3198 PF11433.8 EST46355.1 - 0.12 12.2 0.7 5.2 7.0 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3198) PKcGMP_CC PF16808.5 EST46357.1 - 0.023 14.6 0.7 0.023 14.6 0.7 3.8 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Peptidase_M18 PF02127.15 EST46359.1 - 4.3e-64 216.9 0.0 4.9e-64 216.7 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M20 PF01546.28 EST46359.1 - 0.0017 18.1 0.0 0.0063 16.2 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 CBM46 PF18448.1 EST46359.1 - 0.082 13.2 0.0 0.35 11.2 0.0 2.0 2 0 0 2 2 2 0 Carbohydrate binding domain DUF2787 PF10980.8 EST46362.1 - 0.1 12.8 0.3 23 5.2 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2787) DUF2541 PF10807.8 EST46365.1 - 0.042 13.9 0.0 0.052 13.6 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2541) DUF1681 PF07933.14 EST46366.1 - 1.9e-33 115.2 0.0 2.2e-33 115.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) DUF1262 PF06880.11 EST46366.1 - 0.062 13.7 0.1 1.5 9.2 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1262) RE_ApaLI PF09499.10 EST46367.1 - 0.0029 17.3 0.2 0.0057 16.4 0.2 1.5 1 0 0 1 1 1 1 ApaLI-like restriction endonuclease Peptidase_M20 PF01546.28 EST46368.1 - 2.1e-14 53.7 0.0 3e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EST46368.1 - 1.1e-06 28.5 0.0 2.9e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M42 PF05343.14 EST46368.1 - 0.0058 15.7 0.1 0.054 12.5 0.0 2.4 3 0 0 3 3 3 1 M42 glutamyl aminopeptidase Peptidase_M28 PF04389.17 EST46368.1 - 0.02 14.6 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 Sigma70_r4_2 PF08281.12 EST46368.1 - 0.11 12.2 0.1 0.31 10.7 0.1 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 SHIPPO-rpt PF07004.12 EST46369.1 - 3.9e-07 30.7 28.2 0.012 16.5 3.2 6.2 6 0 0 6 6 6 5 Sperm-tail PG-rich repeat Syntaxin-6_N PF09177.11 EST46370.1 - 0.033 14.7 1.9 0.033 14.7 1.9 1.8 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Spindle_Spc25 PF08234.12 EST46370.1 - 0.067 13.4 3.9 1.3 9.3 0.1 2.8 3 0 0 3 3 3 0 Chromosome segregation protein Spc25 YabA PF06156.13 EST46370.1 - 1.1 9.9 10.2 1.1 9.9 1.7 2.5 2 1 0 2 2 2 0 Initiation control protein YabA Uso1_p115_C PF04871.13 EST46370.1 - 1.4 9.3 5.2 2.7 8.4 5.2 1.5 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Sec2p PF06428.11 EST46370.1 - 1.7 8.7 10.7 0.21 11.6 1.6 3.1 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p ATG16 PF08614.11 EST46371.1 - 0.55 10.4 117.3 0.13 12.5 9.1 7.4 1 1 6 7 7 7 0 Autophagy protein 16 (ATG16) Sec7 PF01369.20 EST46372.1 - 3.9e-37 127.7 12.8 3.9e-37 127.7 12.8 4.5 5 1 0 5 5 5 1 Sec7 domain SET PF00856.28 EST46373.1 - 4e-08 33.8 2.1 1.7e-07 31.8 2.1 1.9 1 1 0 1 1 1 1 SET domain SapC PF07277.11 EST46373.1 - 0.033 13.8 0.5 0.056 13.0 0.5 1.3 1 0 0 1 1 1 0 SapC Mto2_bdg PF12808.7 EST46376.1 - 0.056 13.7 0.2 0.056 13.7 0.2 5.9 6 0 0 6 6 6 0 Micro-tubular organiser Mto1 C-term Mto2-binding region TSC22 PF01166.18 EST46376.1 - 1.9 8.9 34.5 0.17 12.2 0.7 7.3 6 2 1 7 7 7 0 TSC-22/dip/bun family HSDR_N_2 PF13588.6 EST46377.1 - 0.0067 16.4 0.8 0.0067 16.4 0.8 3.1 4 0 0 4 4 4 1 Type I restriction enzyme R protein N terminus (HSDR_N) PDDEXK_9 PF08011.11 EST46377.1 - 0.041 13.8 0.4 0.041 13.8 0.4 2.6 2 1 1 3 3 3 0 PD-(D/E)XK nuclease superfamily DUF3377 PF11857.8 EST46378.1 - 0.69 9.9 5.0 1.5 8.8 5.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Stevor PF17410.2 EST46378.1 - 2.2 7.8 6.1 3.2 7.2 6.1 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame NLPC_P60 PF00877.19 EST46379.1 - 0.00012 22.1 0.1 0.00038 20.4 0.1 1.8 1 1 0 1 1 1 1 NlpC/P60 family Peptidase_C92 PF05708.12 EST46379.1 - 0.052 13.7 0.0 12 5.9 0.0 2.2 2 0 0 2 2 2 0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family Lbh PF15317.6 EST46381.1 - 0.088 13.7 1.2 8.5 7.3 0.3 2.3 2 0 0 2 2 2 0 Cardiac transcription factor regulator, Developmental protein AAA_6 PF12774.7 EST46381.1 - 0.18 10.8 4.8 0.21 10.5 4.8 1.1 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region EF-hand_1 PF00036.32 EST46382.1 - 2.1e-12 45.6 4.8 0.0023 17.3 0.1 3.4 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 EST46382.1 - 1.2e-10 41.7 6.4 2.4e-07 31.1 1.9 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EST46382.1 - 9.9e-10 38.1 8.1 0.00012 21.9 0.1 3.8 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 EST46382.1 - 2.5e-09 36.2 2.9 0.0088 15.5 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EST46382.1 - 3.3e-09 35.9 4.2 0.089 12.8 0.1 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_4 PF12763.7 EST46382.1 - 0.00042 20.2 5.7 0.0034 17.3 1.2 2.6 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EST46382.1 - 0.0017 18.7 0.5 0.011 16.0 0.1 2.0 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Cadherin_5 PF17892.1 EST46382.1 - 0.07 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Cadherin-like domain PsiE PF06146.12 EST46383.1 - 2.1e-11 44.0 0.9 2.1e-11 44.0 0.9 1.7 2 0 0 2 2 2 1 Phosphate-starvation-inducible E DUF4149 PF13664.6 EST46383.1 - 1.3 9.4 8.7 5.6 7.3 3.4 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4149) UCH PF00443.29 EST46386.1 - 2.6e-27 95.9 0.0 1.9e-24 86.6 0.0 3.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EST46386.1 - 0.0016 18.1 7.1 0.0019 17.9 1.3 2.9 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Josephin PF02099.17 EST46386.1 - 0.057 13.5 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Josephin YacG PF03884.14 EST46386.1 - 0.14 11.9 2.2 1.2 8.9 0.2 2.5 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG TPR_12 PF13424.6 EST46387.1 - 0.029 14.7 6.9 3 8.2 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Kazal_2 PF07648.15 EST46387.1 - 0.07 13.3 0.4 0.19 11.9 0.1 1.9 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain TPR_2 PF07719.17 EST46387.1 - 0.088 13.0 2.2 0.57 10.4 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EST46387.1 - 0.18 11.7 2.2 0.35 10.8 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EST46387.1 - 2.5 8.8 8.8 0.46 11.2 1.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Hepsin-SRCR PF09272.10 EST46388.1 - 0.1 13.1 0.7 9.3 6.8 0.0 3.5 4 0 0 4 4 4 0 Hepsin, SRCR domain Toxin_8 PF07365.12 EST46390.1 - 1.6 9.0 6.3 0.61 10.3 0.3 2.8 3 0 0 3 3 3 0 Alpha conotoxin precursor Pyr_redox_2 PF07992.14 EST46391.1 - 0.00062 19.1 0.0 0.00095 18.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SHIPPO-rpt PF07004.12 EST46392.1 - 3e-09 37.4 13.7 0.0011 19.8 0.6 4.7 5 0 0 5 5 5 3 Sperm-tail PG-rich repeat Pkinase PF00069.25 EST46393.1 - 4.4e-68 229.5 0.1 6.1e-68 229.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST46393.1 - 5e-45 153.8 0.1 8.4e-45 153.1 0.1 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EST46393.1 - 1.6e-07 30.9 0.0 4e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EST46393.1 - 0.00013 21.0 0.2 0.00022 20.3 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EST46393.1 - 0.00016 21.7 0.0 0.0018 18.2 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EST46393.1 - 0.029 13.1 0.0 0.068 11.9 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase KIND PF16474.5 EST46393.1 - 0.047 13.6 0.0 0.18 11.7 0.0 2.0 1 1 0 1 1 1 0 Kinase non-catalytic C-lobe domain UN_NPL4 PF11543.8 EST46394.1 - 0.00025 21.4 0.0 0.0011 19.5 0.0 2.2 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 P5CR_dimer PF14748.6 EST46395.1 - 8.7e-22 77.3 0.2 1.6e-21 76.5 0.2 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EST46395.1 - 4e-16 59.4 0.1 8.7e-16 58.3 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EST46395.1 - 2e-09 37.8 0.1 3e-09 37.3 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 EST46395.1 - 2.4e-05 24.4 0.4 3.9e-05 23.7 0.4 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 EST46395.1 - 0.0001 21.7 0.0 0.00015 21.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 EST46395.1 - 0.00036 21.3 0.0 0.00061 20.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Sacchrp_dh_NADP PF03435.18 EST46395.1 - 0.0008 19.7 0.2 0.0012 19.1 0.2 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_Gly3P_dh_N PF01210.23 EST46395.1 - 0.0023 17.9 1.1 0.053 13.5 1.1 2.2 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 EST46395.1 - 0.0036 17.0 0.9 0.014 15.0 0.9 1.9 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_C PF03720.15 EST46395.1 - 0.0053 17.2 0.1 0.0094 16.4 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 3HCDH_N PF02737.18 EST46395.1 - 0.017 15.0 0.2 0.042 13.7 0.1 1.7 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 EST46395.1 - 0.097 13.3 0.0 0.18 12.4 0.0 1.6 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain TrkA_N PF02254.18 EST46395.1 - 0.11 12.8 0.9 1.4 9.2 0.0 2.2 1 1 1 2 2 2 0 TrkA-N domain UDG PF03167.19 EST46396.1 - 7.1e-06 26.1 0.0 5.3e-05 23.2 0.0 2.0 1 1 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF720 PF05302.11 EST46396.1 - 0.019 14.8 0.4 6.3 6.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF720) RET_CLD1 PF17756.1 EST46396.1 - 0.049 13.9 0.1 0.14 12.5 0.0 1.8 2 0 0 2 2 2 0 RET Cadherin like domain 1 PhoU_div PF01865.16 EST46398.1 - 0.007 15.7 1.2 0.011 15.1 0.5 1.6 1 1 1 2 2 2 2 Protein of unknown function DUF47 DUF2680 PF10925.8 EST46398.1 - 0.059 13.4 0.5 0.059 13.4 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) DUF1326 PF07040.11 EST46398.1 - 0.1 12.7 0.2 0.12 12.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1326) zf-C3HC4_3 PF13920.6 EST46400.1 - 2.7e-05 24.0 12.6 5.3e-05 23.0 12.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EST46400.1 - 0.01 15.7 16.3 0.023 14.6 16.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SLC12 PF03522.15 EST46400.1 - 0.011 14.7 0.1 0.019 14.0 0.1 1.2 1 0 0 1 1 1 0 Solute carrier family 12 zf-C3HC4 PF00097.25 EST46400.1 - 0.013 15.3 12.4 0.034 14.0 12.4 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EST46400.1 - 0.033 14.2 6.1 0.18 11.9 6.1 2.2 1 1 1 2 2 2 0 RING-type zinc-finger Prok-RING_4 PF14447.6 EST46400.1 - 0.26 11.2 12.8 0.35 10.8 11.3 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 UPF0728 PF15092.6 EST46400.1 - 0.3 10.9 0.1 0.3 10.9 0.1 2.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0728 zf-RING_2 PF13639.6 EST46400.1 - 4.1 7.8 20.8 0.3 11.5 15.7 1.8 2 0 0 2 2 2 0 Ring finger domain DUF2797 PF10977.8 EST46400.1 - 4.3 7.1 5.6 34 4.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2797) Transketolase_N PF00456.21 EST46402.1 - 1.6e-116 389.0 0.0 2.1e-116 388.5 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EST46402.1 - 1.2e-25 90.2 0.0 2.3e-25 89.3 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain TPP_enzyme_C PF02775.21 EST46402.1 - 6e-06 26.1 0.1 6e-05 22.9 0.0 2.7 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 EST46402.1 - 2.1e-05 23.9 0.0 0.00043 19.6 0.0 2.3 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.20 EST46402.1 - 0.00011 22.1 0.3 0.0031 17.4 0.1 2.9 2 1 0 2 2 2 1 Transketolase, C-terminal domain E1_dh PF00676.20 EST46402.1 - 0.01 14.8 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component DUF3791 PF12668.7 EST46402.1 - 0.046 13.8 0.1 3.1 7.9 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3791) Helicase_C PF00271.31 EST46404.1 - 1.6e-24 86.4 2.2 1.2e-23 83.6 0.1 3.0 2 1 1 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 EST46404.1 - 2.1e-20 73.2 0.4 6.8e-20 71.6 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EST46404.1 - 6.7e-12 45.7 0.1 6.7e-12 45.7 0.1 2.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 EST46404.1 - 0.0011 18.7 0.4 0.0028 17.3 0.0 1.9 2 0 0 2 2 2 1 SWI2/SNF2 ATPase AAA_30 PF13604.6 EST46404.1 - 0.0065 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EST46404.1 - 0.036 13.5 0.1 0.085 12.3 0.1 1.7 1 1 0 1 1 1 0 PhoH-like protein DUF2312 PF10073.9 EST46405.1 - 1.4 8.7 10.2 8.5 6.1 0.0 4.2 2 2 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2312) HALZ PF02183.18 EST46405.1 - 1.6 9.0 30.8 0.7 10.2 0.4 7.2 7 0 0 7 7 7 0 Homeobox associated leucine zipper RIB43A PF05914.12 EST46407.1 - 6.9e-32 110.6 60.9 9.9e-32 110.1 60.9 1.2 1 0 0 1 1 1 1 RIB43A ASH PF15780.5 EST46408.1 - 0.052 13.8 0.0 0.18 12.1 0.0 1.9 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TylF PF05711.11 EST46408.1 - 0.16 11.2 0.0 0.3 10.3 0.0 1.4 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) Cation_efflux PF01545.21 EST46409.1 - 5.6e-19 68.7 14.7 2e-18 66.9 14.7 1.8 1 1 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EST46409.1 - 4e-06 26.9 0.1 1e-05 25.6 0.1 1.7 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter RabGAP-TBC PF00566.18 EST46409.1 - 0.058 13.0 0.2 0.22 11.2 0.2 2.1 1 1 0 1 1 1 0 Rab-GTPase-TBC domain Myb_DNA-binding PF00249.31 EST46411.1 - 2.1e-21 75.8 5.5 6.1e-11 42.3 0.6 2.5 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST46411.1 - 3.8e-20 71.9 5.7 5e-12 45.9 1.2 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EST46411.1 - 0.0018 18.3 6.2 0.013 15.5 2.0 2.4 1 1 1 2 2 2 2 SLIDE DUF722 PF05263.11 EST46411.1 - 0.017 15.4 6.4 0.12 12.5 1.3 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF722) SANT_DAMP1_like PF16282.5 EST46411.1 - 0.25 11.5 10.8 0.098 12.9 2.3 2.6 2 1 1 3 3 3 0 SANT/Myb-like domain of DAMP1 DUF4065 PF13274.6 EST46411.1 - 0.27 12.2 4.1 4 8.4 4.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF4065) Myb_DNA-bind_3 PF12776.7 EST46411.1 - 0.78 10.8 9.9 4.2 8.4 6.7 2.9 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain zf-RING_2 PF13639.6 EST46412.1 - 4.6e-10 39.7 6.3 6.6e-10 39.2 6.3 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EST46412.1 - 3.1e-09 36.5 6.4 4.6e-09 36.0 6.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EST46412.1 - 4.7e-08 32.9 5.3 6.6e-08 32.4 5.3 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EST46412.1 - 7.8e-08 32.1 6.7 1.2e-07 31.5 6.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EST46412.1 - 6.1e-07 29.4 5.8 3.6e-05 23.7 2.0 2.2 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EST46412.1 - 6.3e-07 29.2 3.9 8.4e-07 28.7 3.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EST46412.1 - 1.8e-06 27.6 3.7 4.5e-06 26.4 3.8 1.6 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 EST46412.1 - 3e-06 26.9 7.4 0.0011 18.7 3.1 2.4 2 0 0 2 2 2 2 RING-like zinc finger Prok-RING_4 PF14447.6 EST46412.1 - 2.2e-05 24.2 9.8 0.00047 19.9 9.1 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EST46412.1 - 0.00082 19.5 4.3 0.0065 16.6 5.0 1.9 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 EST46412.1 - 0.00089 19.0 3.5 0.0015 18.3 3.5 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_1 PF14446.6 EST46412.1 - 0.0018 18.1 1.4 0.65 10.0 0.3 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 1 zf-ANAPC11 PF12861.7 EST46412.1 - 0.007 16.4 4.0 0.033 14.2 4.0 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 EST46412.1 - 0.0096 16.2 1.6 0.0096 16.2 1.6 2.1 2 0 0 2 2 2 1 RING-like domain zf-Di19 PF05605.12 EST46412.1 - 0.013 15.8 0.6 4.2 7.7 0.0 2.5 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_3rep PF18868.1 EST46412.1 - 0.029 15.0 1.5 0.033 14.8 1.5 1.1 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats zf-rbx1 PF12678.7 EST46412.1 - 0.031 14.6 7.9 0.18 12.1 7.8 2.2 1 1 1 2 2 2 0 RING-H2 zinc finger domain zf-C3H2C3 PF17122.5 EST46412.1 - 0.044 13.8 7.1 0.13 12.4 7.1 1.7 1 1 0 1 1 1 0 Zinc-finger zf-WRNIP1_ubi PF18279.1 EST46412.1 - 0.044 14.4 6.4 1.2 10.0 1.0 3.5 3 0 0 3 3 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Thioredoxin_4 PF13462.6 EST46412.1 - 0.047 13.8 0.3 0.34 11.1 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin Zn_ribbon_17 PF17120.5 EST46412.1 - 0.055 13.1 2.0 0.082 12.5 2.0 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-met2 PF12907.7 EST46412.1 - 0.062 13.5 0.2 0.062 13.5 0.2 2.4 3 0 0 3 3 3 0 Zinc-binding Rad50_zn_hook PF04423.14 EST46412.1 - 0.072 12.9 1.2 11 6.0 0.0 3.1 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-C2H2_4 PF13894.6 EST46412.1 - 0.11 13.4 4.2 0.18 12.8 0.1 2.4 2 1 0 2 2 2 0 C2H2-type zinc finger Zf_RING PF16744.5 EST46412.1 - 0.19 11.9 5.1 0.42 10.8 1.1 2.2 1 1 1 2 2 2 0 KIAA1045 RING finger Zn-C2H2_12 PF18112.1 EST46412.1 - 0.19 12.2 5.2 0.95 10.0 0.2 2.7 3 0 0 3 3 2 0 Autophagy receptor zinc finger-C2H2 domain DUF1178 PF06676.11 EST46412.1 - 0.42 11.0 3.3 0.13 12.7 0.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1178) zf-C3HC4_5 PF17121.5 EST46412.1 - 0.58 10.1 6.8 3.9 7.4 6.9 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UBZ_FAAP20 PF15750.5 EST46412.1 - 0.67 9.9 4.0 15 5.7 0.4 2.3 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger Antistasin PF02822.14 EST46412.1 - 3.7 8.3 7.4 5.6 7.7 1.2 2.3 2 0 0 2 2 2 0 Antistasin family WD40_like PF17005.5 EST46413.1 - 0.00024 20.5 6.0 0.00043 19.7 4.9 1.9 1 1 0 2 2 2 1 WD40-like domain BLF1 PF17752.1 EST46413.1 - 0.26 10.6 0.5 4 6.7 0.1 2.6 2 1 1 3 3 3 0 Burkholderia lethal factor 1 TMF_DNA_bd PF12329.8 EST46414.1 - 0.011 15.7 4.5 0.011 15.7 4.5 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4472 PF14739.6 EST46414.1 - 0.034 14.9 8.1 0.034 14.9 8.1 2.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4472) BLOC1S3 PF15753.5 EST46414.1 - 0.22 11.7 12.2 0.1 12.7 8.6 2.1 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 LUC7 PF03194.15 EST46414.1 - 1.3 8.7 8.4 14 5.2 8.4 2.1 1 1 0 1 1 1 0 LUC7 N_terminus Tropomyosin_1 PF12718.7 EST46414.1 - 1.6 8.8 14.3 0.14 12.4 7.5 2.5 1 1 1 2 2 2 0 Tropomyosin like CEP63 PF17045.5 EST46414.1 - 1.9 8.3 19.5 0.23 11.4 13.7 2.0 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa Fungal_TACC PF12709.7 EST46414.1 - 2.8 8.4 8.0 19 5.8 0.3 3.6 3 0 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins Syntaxin-6_N PF09177.11 EST46414.1 - 2.9 8.5 14.6 20 5.8 9.0 3.2 2 1 0 2 2 2 0 Syntaxin 6, N-terminal FANCI_S1-cap PF14674.6 EST46414.1 - 8.9 6.5 7.2 4.4 7.5 0.1 3.5 4 0 0 4 4 4 0 FANCI solenoid 1 cap MCC-bdg_PDZ PF10506.9 EST46415.1 - 0.066 13.2 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Hepar_II_III_N PF16889.5 EST46416.1 - 0.018 14.3 0.6 0.035 13.4 0.6 1.4 1 0 0 1 1 1 0 Heparinase II/III N-terminus MOZART1 PF12554.8 EST46416.1 - 2.6 7.9 7.4 1.6 8.6 1.4 3.1 3 0 0 3 3 3 0 Mitotic-spindle organizing gamma-tubulin ring associated Profilin PF00235.19 EST46417.1 - 0.12 12.7 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Profilin Cation_ATPase_C PF00689.21 EST46418.1 - 6.4e-44 149.8 9.8 6.4e-44 149.8 9.8 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EST46418.1 - 5.4e-37 127.1 2.8 5.4e-37 127.1 2.8 3.5 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 EST46418.1 - 1.5e-19 71.2 0.1 1.8e-18 67.6 0.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EST46418.1 - 2.2e-15 56.1 0.0 7e-15 54.5 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EST46418.1 - 1.3e-07 31.6 0.0 2.9e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EST46418.1 - 1.5e-07 31.4 0.4 8.4e-05 22.4 0.2 2.8 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EST46418.1 - 0.014 15.9 0.0 0.025 15.0 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Peptidase_M56 PF05569.11 EST46418.1 - 0.033 13.4 0.6 0.12 11.6 0.6 2.0 1 0 0 1 1 1 0 BlaR1 peptidase M56 Hydrolase_6 PF13344.6 EST46418.1 - 0.061 13.4 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Dor1 PF04124.12 EST46418.1 - 0.066 11.9 0.1 0.18 10.4 0.0 1.8 2 0 0 2 2 2 0 Dor1-like family DUF2157 PF09925.9 EST46418.1 - 7.5 6.3 10.9 3.4 7.5 0.4 3.5 4 0 0 4 4 4 0 Predicted membrane protein (DUF2157) RabGAP-TBC PF00566.18 EST46419.1 - 4.2e-10 39.6 5.7 4.2e-10 39.6 5.7 2.3 2 1 1 3 3 3 1 Rab-GTPase-TBC domain HALZ PF02183.18 EST46420.1 - 0.063 13.5 2.1 1.1 9.6 0.6 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper Tektin PF03148.14 EST46420.1 - 0.11 11.2 6.9 0.8 8.4 0.8 2.1 1 1 1 2 2 2 0 Tektin family Siah-Interact_N PF09032.11 EST46420.1 - 0.18 12.1 1.1 0.43 10.9 0.3 2.0 1 1 1 2 2 2 0 Siah interacting protein, N terminal bZIP_1 PF00170.21 EST46420.1 - 0.79 9.9 5.5 0.66 10.1 1.3 2.5 1 1 1 2 2 2 0 bZIP transcription factor zinc_ribbon_13 PF09855.9 EST46421.1 - 0.038 14.2 0.6 0.16 12.1 0.3 2.3 2 0 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) EMC3_TMCO1 PF01956.16 EST46422.1 - 2.2e-07 30.7 10.2 2.5e-07 30.6 9.2 1.5 1 1 1 2 2 2 1 Integral membrane protein EMC3/TMCO1-like EzrA PF06160.12 EST46422.1 - 0.0014 16.9 0.8 0.0019 16.5 0.8 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA BLOC1_2 PF10046.9 EST46422.1 - 0.007 16.7 1.8 0.011 16.1 1.8 1.3 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 PUL PF08324.11 EST46422.1 - 0.011 15.0 0.6 0.018 14.3 0.6 1.2 1 0 0 1 1 1 0 PUL domain BORCS7 PF16088.5 EST46422.1 - 0.028 14.7 1.5 0.05 13.9 1.5 1.4 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 7 DUF812 PF05667.11 EST46422.1 - 0.057 12.3 3.6 0.074 11.9 2.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF812) DHR10 PF18595.1 EST46422.1 - 0.098 12.7 5.3 0.15 12.1 5.3 1.2 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Telomerase_RBD PF12009.8 EST46422.1 - 0.54 10.4 7.0 2.9 8.0 7.2 1.9 2 0 0 2 2 2 0 Telomerase ribonucleoprotein complex - RNA binding domain TylF PF05711.11 EST46425.1 - 0.063 12.5 2.5 0.075 12.3 0.0 2.2 3 0 0 3 3 3 0 Macrocin-O-methyltransferase (TylF) DUF4677 PF15726.5 EST46425.1 - 0.082 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4677) Rtt106 PF08512.12 EST46425.1 - 0.5 10.8 5.2 0.21 12.0 0.7 2.3 2 0 0 2 2 2 0 Histone chaperone Rttp106-like Ribophorin_I PF04597.14 EST46426.1 - 7.9e-20 71.5 2.5 3e-19 69.6 2.5 1.8 1 1 0 1 1 1 1 Ribophorin I EF-hand_6 PF13405.6 EST46427.1 - 2.1e-06 27.2 3.3 0.0035 17.2 0.0 3.4 4 1 1 5 5 5 2 EF-hand domain EF-hand_7 PF13499.6 EST46427.1 - 5.4e-06 26.8 3.2 0.014 15.8 0.0 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EST46427.1 - 0.00028 20.2 6.9 0.00038 19.8 0.0 3.8 5 0 0 5 5 5 1 EF hand EF-hand_5 PF13202.6 EST46427.1 - 0.054 13.0 4.0 2.8 7.6 0.0 3.5 3 1 1 4 4 4 0 EF hand DUF4576 PF15144.6 EST46427.1 - 0.095 12.6 0.4 0.25 11.3 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4576) EF-hand_8 PF13833.6 EST46427.1 - 3.1 7.7 9.3 5.4 7.0 0.0 3.0 4 1 0 4 4 4 0 EF-hand domain pair Cohesin_load PF10345.9 EST46428.1 - 0.0018 16.8 4.5 0.0021 16.6 4.5 1.1 1 0 0 1 1 1 1 Cohesin loading factor Holin_BhlA PF10960.8 EST46428.1 - 0.52 10.3 6.9 5.9 6.9 0.5 2.3 2 0 0 2 2 2 0 BhlA holin family RPAP3_C PF13877.6 EST46429.1 - 0.015 15.8 0.0 0.04 14.5 0.0 1.8 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 KH_1 PF00013.29 EST46431.1 - 1e-05 25.3 0.3 3.4e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 KH domain KH_4 PF13083.6 EST46431.1 - 0.52 10.2 2.4 4.9 7.1 0.0 2.7 3 0 0 3 3 3 0 KH domain Leader_CPA1 PF08252.11 EST46432.1 - 2.9 7.4 5.6 11 5.5 1.1 2.5 2 0 0 2 2 2 0 arg-2/CPA1 leader peptide CENP-K PF11802.8 EST46433.1 - 0.019 14.6 8.1 0.029 13.9 8.1 1.4 1 0 0 1 1 1 0 Centromere-associated protein K DUF5344 PF17279.2 EST46433.1 - 0.032 14.8 8.5 0.089 13.4 8.5 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5344) Maelstrom PF13017.6 EST46433.1 - 0.04 13.6 2.9 0.081 12.6 1.0 2.4 2 1 1 3 3 3 0 piRNA pathway germ-plasm component HAUS-augmin3 PF14932.6 EST46433.1 - 0.059 13.0 13.4 0.095 12.3 13.4 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 HALZ PF02183.18 EST46433.1 - 0.2 11.9 0.4 0.2 11.9 0.4 3.4 4 0 0 4 4 4 0 Homeobox associated leucine zipper Cnn_1N PF07989.11 EST46433.1 - 5.9 7.1 16.2 0.22 11.7 1.6 2.9 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Atg14 PF10186.9 EST46433.1 - 8.6 5.3 12.5 12 4.9 12.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MAS20 PF02064.15 EST46435.1 - 0.04 14.0 1.9 0.11 12.6 1.9 1.7 1 1 0 1 1 1 0 MAS20 protein import receptor DUF5367 PF17329.2 EST46436.1 - 0.012 15.7 0.0 0.015 15.4 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5367) DUF2827 PF10933.8 EST46437.1 - 0.045 12.4 0.0 0.048 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2827) Cyclin_N PF00134.23 EST46439.1 - 4.4e-15 55.5 0.0 9.4e-15 54.5 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EST46439.1 - 0.00044 20.3 0.3 0.0022 18.0 0.0 2.4 2 0 0 2 2 2 1 Cyclin, C-terminal domain Peptidase_M20 PF01546.28 EST46440.1 - 8.9e-07 28.8 0.0 3.1e-06 27.0 0.0 1.8 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EST46440.1 - 4e-05 23.5 0.1 0.00016 21.5 0.1 2.1 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M42 PF05343.14 EST46440.1 - 0.00042 19.4 0.0 0.35 9.8 0.0 2.8 3 0 0 3 3 3 2 M42 glutamyl aminopeptidase Peptidase_M28 PF04389.17 EST46440.1 - 0.057 13.1 0.0 3.8 7.2 0.0 2.4 2 0 0 2 2 2 0 Peptidase family M28 PXA PF02194.15 EST46441.1 - 0.013 15.5 0.4 0.017 15.1 0.4 1.2 1 0 0 1 1 1 0 PXA domain Herpes_IE68 PF02479.16 EST46441.1 - 0.029 14.0 0.2 0.058 13.0 0.0 1.5 2 0 0 2 2 2 0 Herpesvirus immediate early protein 4HFCP_synth PF04476.13 EST46441.1 - 0.052 13.3 0.0 0.069 12.9 0.0 1.1 1 0 0 1 1 1 0 4-HFC-P synthase DnaB_2 PF07261.11 EST46441.1 - 1.4 8.8 5.8 0.68 9.7 1.5 2.5 2 1 1 3 3 3 0 Replication initiation and membrane attachment CTC1 PF15489.6 EST46442.1 - 0.053 11.0 0.1 0.056 11.0 0.1 1.0 1 0 0 1 1 1 0 CST, telomere maintenance, complex subunit CTC1 Alg14 PF08660.11 EST46442.1 - 0.094 12.6 0.0 0.098 12.6 0.0 1.1 1 0 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like Myosin-VI_CBD PF16521.5 EST46442.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Myosin VI cargo binding domain XRN_N PF03159.18 EST46443.1 - 0.00087 18.8 0.7 0.0026 17.3 0.7 1.9 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus DUF563 PF04577.14 EST46444.1 - 1.5 8.9 5.1 13 5.8 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF563) FAM76 PF16046.5 EST46444.1 - 3.9 6.7 15.5 0.13 11.6 4.8 2.3 2 0 0 2 2 2 0 FAM76 protein OCRE PF17780.1 EST46445.1 - 1.5e-06 28.1 7.1 0.04 13.9 0.0 4.5 4 0 0 4 4 4 2 OCRE domain DUF4585 PF15232.6 EST46445.1 - 0.00053 20.0 4.5 4.4 7.4 0.0 4.5 4 0 0 4 4 4 3 Domain of unknown function (DUF4585) BA14K PF07886.11 EST46445.1 - 2.7 7.9 6.5 11 6.0 0.2 3.2 3 0 0 3 3 3 0 BA14K-like protein LRR_4 PF12799.7 EST46446.1 - 5.6e-09 36.1 7.6 4.3e-07 30.1 3.3 2.5 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EST46446.1 - 0.0006 19.5 4.8 0.0011 18.6 4.2 1.8 1 1 0 1 1 1 1 Leucine rich repeat LRR_9 PF14580.6 EST46446.1 - 0.0031 17.0 2.3 0.0047 16.4 2.3 1.4 1 1 0 1 1 1 1 Leucine-rich repeat ATG16 PF08614.11 EST46446.1 - 0.027 14.7 1.9 0.037 14.2 1.9 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) CRA PF06589.11 EST46446.1 - 0.037 14.1 1.1 0.054 13.6 1.1 1.2 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) DUF1192 PF06698.11 EST46446.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) SlyX PF04102.12 EST46446.1 - 0.21 12.2 2.1 0.65 10.7 2.1 1.8 1 0 0 1 1 1 0 SlyX LRR_1 PF00560.33 EST46446.1 - 0.32 11.7 3.9 62 4.7 0.1 4.1 4 0 0 4 4 4 0 Leucine Rich Repeat ATF7IP_BD PF16788.5 EST46447.1 - 0.012 15.8 8.4 0.015 15.4 8.4 1.2 1 0 0 1 1 1 0 ATF-interacting protein binding domain DUF2681 PF10883.8 EST46447.1 - 0.52 10.8 13.0 0.14 12.5 9.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) TPK_catalytic PF04263.16 EST46448.1 - 0.0036 17.3 0.3 0.0038 17.3 0.3 1.1 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain Myb_DNA-binding PF00249.31 EST46448.1 - 0.041 14.1 0.0 0.072 13.3 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain PCI PF01399.27 EST46450.1 - 0.0091 16.5 2.3 0.18 12.3 0.2 2.9 2 0 0 2 2 2 1 PCI domain Fes1 PF08609.10 EST46451.1 - 0.039 14.8 0.4 0.046 14.6 0.4 1.1 1 0 0 1 1 1 0 Nucleotide exchange factor Fes1 NolV PF06635.12 EST46452.1 - 0.024 14.0 0.0 0.026 13.9 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein NolV PHM7_cyt PF14703.6 EST46452.1 - 0.068 13.4 1.2 0.087 13.1 1.2 1.1 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter EMP24_GP25L PF01105.24 EST46453.1 - 1.3e-22 80.6 5.5 1.5e-22 80.4 5.5 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Redoxin PF08534.10 EST46454.1 - 0.0097 15.6 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 1 Redoxin Adaptin_N PF01602.20 EST46455.1 - 1.3e-64 218.6 21.8 1.3e-64 218.6 21.8 1.4 2 0 0 2 2 2 1 Adaptin N terminal region HEAT_2 PF13646.6 EST46455.1 - 1.7e-06 28.3 0.9 0.14 12.6 0.4 3.8 4 0 0 4 4 4 2 HEAT repeats Helitron_like_N PF14214.6 EST46455.1 - 0.0085 16.3 0.1 0.023 14.9 0.1 1.7 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PAD_N PF08526.10 EST46455.1 - 0.017 15.5 0.0 0.055 13.9 0.0 1.9 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) N-terminal domain HEAT PF02985.22 EST46455.1 - 0.038 14.3 0.4 0.55 10.6 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat V-ATPase_H_C PF11698.8 EST46455.1 - 0.092 12.9 5.6 1.3 9.2 0.1 4.2 4 1 0 4 4 4 0 V-ATPase subunit H XRN_N PF03159.18 EST46456.1 - 1.4e-47 162.1 0.1 8.5e-43 146.5 0.0 2.6 2 0 0 2 2 2 2 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 EST46456.1 - 4e-21 75.5 7.1 2.2e-20 73.1 7.1 2.2 1 1 0 1 1 1 1 Xrn1 helical domain DrrA_P4M PF14860.6 EST46456.1 - 0.54 10.1 8.2 3.2 7.7 0.5 4.3 4 0 0 4 4 4 0 DrrA phosphatidylinositol 4-phosphate binding domain PdaC PF13739.6 EST46456.1 - 0.95 10.5 12.2 0.032 15.2 2.7 3.4 2 0 0 2 2 2 0 Deacetylase PdaC Metallophos PF00149.28 EST46457.1 - 5e-28 99.0 0.8 8.5e-28 98.2 0.8 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_2 PF07719.17 EST46457.1 - 3.2e-12 45.6 3.8 0.015 15.4 0.0 4.0 5 0 0 5 5 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EST46457.1 - 9.1e-12 44.5 2.0 3e-06 26.8 0.0 3.5 3 0 0 3 3 3 2 TPR repeat TPR_1 PF00515.28 EST46457.1 - 1.9e-11 43.2 1.8 0.0017 18.1 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 EST46457.1 - 3.6e-06 27.2 0.5 0.0053 17.0 0.1 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EST46457.1 - 1.4e-05 25.6 0.0 3.1e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 EST46457.1 - 1.9e-05 24.5 0.5 7.4 7.1 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 EST46457.1 - 0.0002 21.8 0.6 3 8.4 0.0 3.5 3 1 1 4 4 3 2 Tetratricopeptide repeat Metallophos_2 PF12850.7 EST46457.1 - 0.00032 20.9 0.0 0.00091 19.5 0.0 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain TPR_17 PF13431.6 EST46457.1 - 0.0005 20.3 0.2 0.77 10.3 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EST46457.1 - 0.0012 18.7 0.0 1.1 9.4 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Endosulfine PF04667.17 EST46457.1 - 0.032 14.3 0.0 0.098 12.8 0.0 1.8 1 0 0 1 1 1 0 cAMP-regulated phosphoprotein/endosulfine conserved region TPR_14 PF13428.6 EST46457.1 - 0.056 14.3 0.3 14 6.8 0.1 3.3 1 1 2 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 EST46457.1 - 0.21 12.0 0.0 0.37 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial transcriptional activator domain DUF3471 PF11954.8 EST46459.1 - 0.11 13.0 0.2 0.58 10.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3471) tRNA-synt_1b PF00579.25 EST46460.1 - 1.5e-08 34.3 0.0 2.4e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DHHC PF01529.20 EST46461.1 - 4.4e-14 52.7 13.3 4.4e-14 52.7 13.3 2.6 2 1 0 2 2 2 1 DHHC palmitoyltransferase zf-CRD PF17979.1 EST46461.1 - 0.00023 21.3 3.3 0.00044 20.4 3.3 1.5 1 1 0 1 1 1 1 Cysteine rich domain with multizinc binding regions Glucos_trans_II PF14264.6 EST46461.1 - 0.062 12.6 10.3 0.086 12.2 10.3 1.1 1 0 0 1 1 1 0 Glucosyl transferase GtrII Nup54_57_C PF18570.1 EST46462.1 - 0.091 12.4 0.1 0.21 11.2 0.1 1.6 1 0 0 1 1 1 0 NUP57/Nup54 C-terminal domain DUF3902 PF13042.6 EST46463.1 - 0.17 11.5 6.5 0.095 12.3 4.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3902) Glyco_transf_8 PF01501.20 EST46464.1 - 4.5e-11 42.8 1.0 3.1e-08 33.5 0.1 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 8 Peptidase_C58 PF03543.14 EST46466.1 - 0.035 13.8 1.4 0.044 13.5 1.4 1.1 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen NPFF PF15085.6 EST46466.1 - 0.098 13.0 1.7 0.12 12.7 1.7 1.1 1 0 0 1 1 1 0 Neuropeptide FF Aldo_ket_red PF00248.21 EST46467.1 - 5.1e-50 170.3 0.0 9.9e-50 169.4 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family ECSCR PF15820.5 EST46469.1 - 0.002 17.9 0.5 0.0056 16.5 0.5 1.7 1 0 0 1 1 1 1 Endothelial cell-specific chemotaxis regulator s48_45 PF07422.13 EST46469.1 - 0.013 16.0 1.6 0.019 15.6 0.3 1.9 2 0 0 2 2 2 0 Sexual stage antigen s48/45 domain Shisa PF13908.6 EST46469.1 - 0.036 14.3 0.5 0.058 13.6 0.5 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Copine PF07002.16 EST46471.1 - 2.8e-25 89.0 0.2 4.1e-25 88.5 0.2 1.1 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 EST46471.1 - 1.2e-09 38.6 0.1 1.9e-09 37.9 0.1 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus SPG48 PF14764.6 EST46472.1 - 0.046 14.2 0.1 0.052 14.0 0.1 1.1 1 0 0 1 1 1 0 AP-5 complex subunit, vesicle trafficking GRIN_C PF15235.6 EST46472.1 - 1.5 9.0 5.4 6.8 6.9 5.4 1.8 1 1 0 1 1 1 0 G protein-regulated inducer of neurite outgrowth C-terminus Copine PF07002.16 EST46473.1 - 3.9e-26 91.9 0.0 5.5e-26 91.4 0.0 1.2 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 EST46473.1 - 7.8e-10 39.2 0.0 1.2e-09 38.6 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus Methyltransf_25 PF13649.6 EST46474.1 - 8.2e-07 29.6 0.0 1.5e-06 28.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EST46474.1 - 8.6e-07 28.9 0.2 1.2e-06 28.4 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EST46474.1 - 1.7e-05 25.5 0.0 2.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EST46474.1 - 1.9e-05 25.2 0.0 2.9e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EST46474.1 - 0.00022 21.1 0.0 0.00026 20.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 EST46474.1 - 0.00026 20.7 0.0 0.00032 20.4 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) TPMT PF05724.11 EST46474.1 - 0.00028 20.6 0.0 0.00038 20.2 0.0 1.4 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) DpnI PF06044.12 EST46474.1 - 0.015 15.0 0.1 0.036 13.7 0.1 1.6 1 0 0 1 1 1 0 Dam-replacing family Methyltransf_5 PF01795.19 EST46474.1 - 0.018 14.6 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 MraW methylase family TRF PF08558.10 EST46474.1 - 0.021 14.4 0.2 0.034 13.7 0.0 1.4 2 0 0 2 2 2 0 Telomere repeat binding factor (TRF) TehB PF03848.14 EST46474.1 - 0.065 12.6 0.0 0.096 12.1 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Phage_sheath_1C PF17482.2 EST46474.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Phage tail sheath C-terminal domain Thioredoxin_8 PF13905.6 EST46474.1 - 0.11 12.8 0.5 2.4 8.6 0.0 2.4 2 1 0 2 2 2 0 Thioredoxin-like s48_45 PF07422.13 EST46476.1 - 0.0095 16.5 1.1 0.019 15.6 0.3 1.9 2 0 0 2 2 2 1 Sexual stage antigen s48/45 domain tRNA-synt_1b PF00579.25 EST46477.1 - 2.8e-16 59.7 0.0 1.2e-13 51.0 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) BcrAD_BadFG PF01869.20 EST46483.1 - 0.0002 21.0 0.0 0.00023 20.7 0.0 1.4 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family Glucokinase PF02685.16 EST46483.1 - 0.083 11.9 0.0 6.9 5.6 0.0 2.3 2 0 0 2 2 2 0 Glucokinase NMT PF01233.19 EST46484.1 - 1.1e-31 109.8 0.2 3.3e-31 108.3 0.0 1.8 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.15 EST46484.1 - 9e-28 97.2 4.1 1.3e-27 96.7 4.1 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_1 PF00583.25 EST46484.1 - 0.0015 18.7 0.0 0.12 12.6 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Rdx PF10262.9 EST46486.1 - 0.00091 19.4 0.0 0.0018 18.4 0.0 1.6 1 1 0 1 1 1 1 Rdx family Sec1 PF00995.23 EST46487.1 - 7e-12 45.4 0.4 7.4e-12 45.3 0.4 1.2 1 0 0 1 1 1 1 Sec1 family DSPc PF00782.20 EST46488.1 - 0.0037 17.1 2.0 0.0068 16.2 2.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF4505 PF14956.6 EST46488.1 - 0.028 14.2 0.1 0.045 13.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4505) s48_45 PF07422.13 EST46488.1 - 1.8 9.1 8.0 4.6 7.9 7.2 2.2 1 1 1 2 2 2 0 Sexual stage antigen s48/45 domain DUF3908 PF13048.6 EST46489.1 - 0.006 16.8 0.2 0.0087 16.3 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3908) CrtC PF07143.11 EST46489.1 - 0.062 14.0 0.0 0.069 13.8 0.0 1.1 1 0 0 1 1 1 0 CrtC N-terminal lipocalin domain Octopine_DH PF02317.17 EST46491.1 - 0.014 15.5 0.5 0.035 14.2 0.0 1.9 3 0 0 3 3 3 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Rdx PF10262.9 EST46492.1 - 1.1e-08 35.2 0.0 1.3e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Rdx family Cpn60_TCP1 PF00118.24 EST46493.1 - 9.2e-150 499.5 7.4 1.1e-149 499.3 7.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DHHC PF01529.20 EST46494.1 - 3.7e-17 62.7 7.3 3.7e-17 62.7 7.3 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase AAA PF00004.29 EST46495.1 - 3.8e-31 108.3 0.0 1.5e-30 106.3 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EST46495.1 - 7.5e-19 67.4 0.0 1.3e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EST46495.1 - 1.2e-14 53.8 0.1 2.6e-14 52.7 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EST46495.1 - 2.7e-05 24.2 0.5 0.00046 20.2 0.1 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EST46495.1 - 4e-05 23.8 0.0 0.00012 22.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EST46495.1 - 0.0001 22.7 0.3 0.00024 21.5 0.0 1.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EST46495.1 - 0.00018 21.8 0.3 0.0024 18.2 0.3 2.3 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EST46495.1 - 0.0026 17.5 0.0 0.012 15.3 0.0 2.1 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EST46495.1 - 0.0078 16.8 0.0 0.033 14.7 0.0 2.1 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EST46495.1 - 0.0081 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EST46495.1 - 0.047 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 EST46495.1 - 0.084 12.6 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain CM_2 PF01817.21 EST46495.1 - 0.11 12.9 1.3 0.31 11.4 1.3 1.8 1 0 0 1 1 1 0 Chorismate mutase type II RNA_helicase PF00910.22 EST46495.1 - 0.16 12.4 0.0 0.33 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 EST46495.1 - 0.46 11.0 3.3 1.6 9.2 0.0 2.5 2 1 0 2 2 2 0 ABC transporter AAA_23 PF13476.6 EST46495.1 - 0.5 10.8 8.6 7 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain PITH PF06201.13 EST46497.1 - 3.2e-13 50.1 1.7 3.8e-13 49.9 1.7 1.0 1 0 0 1 1 1 1 PITH domain MBF2 PF15868.5 EST46497.1 - 0.1 13.2 0.1 0.13 12.8 0.1 1.4 1 0 0 1 1 1 0 Transcription activator MBF2 DUF1689 PF07954.11 EST46498.1 - 0.018 15.4 0.4 0.019 15.4 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1689) eIF3_subunit PF08597.10 EST46499.1 - 4.1e-07 30.2 15.9 6.5e-07 29.5 15.9 1.3 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit CBM53 PF16760.5 EST46499.1 - 1.4 9.6 3.7 1.5 9.4 1.2 2.2 2 0 0 2 2 2 0 Starch/carbohydrate-binding module (family 53) UIM PF02809.20 EST46501.1 - 0.0074 16.1 0.4 0.019 14.9 0.4 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif LpxI_N PF17930.1 EST46501.1 - 0.054 13.4 0.0 0.086 12.7 0.0 1.4 1 0 0 1 1 1 0 LpxI N-terminal domain DUF737 PF05300.11 EST46504.1 - 0.068 13.5 14.6 0.11 12.8 14.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Occludin_ELL PF07303.13 EST46504.1 - 0.2 12.4 11.3 0.52 11.1 3.3 2.7 1 1 1 2 2 2 0 Occludin homology domain FAM76 PF16046.5 EST46504.1 - 0.25 10.7 14.2 0.039 13.3 10.2 1.6 1 1 0 1 1 1 0 FAM76 protein Spectrin PF00435.21 EST46504.1 - 0.68 10.5 12.0 0.76 10.3 1.6 2.8 1 1 1 2 2 2 0 Spectrin repeat PIN_8 PF18476.1 EST46504.1 - 0.76 9.6 10.1 1.2 8.9 10.1 1.2 1 0 0 1 1 1 0 PIN like domain ParB PF08775.10 EST46504.1 - 0.95 10.0 10.1 0.15 12.6 3.8 2.3 1 1 1 2 2 2 0 ParB family WDCP PF15390.6 EST46504.1 - 1.8 6.9 11.4 0.7 8.2 9.4 1.3 1 1 0 1 1 1 0 WD repeat and coiled-coil-containing protein family DUF2937 PF11157.8 EST46504.1 - 2.2 8.0 9.8 1.1 9.0 6.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) TSP_NTD PF17804.1 EST46505.1 - 0.0067 16.7 5.7 0.011 16.0 5.7 1.5 1 0 0 1 1 1 1 Tail specific protease N-terminal domain DUF1192 PF06698.11 EST46505.1 - 0.095 12.8 2.5 0.34 11.0 2.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF4094 PF13334.6 EST46505.1 - 0.9 10.0 3.9 2 8.9 3.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) GlcNAc-1_reg PF18440.1 EST46508.1 - 0.56 10.5 4.4 1.6 9.0 0.1 3.6 4 0 0 4 4 4 0 Putative GlcNAc-1 phosphotransferase regulatory domain SL4P PF17618.2 EST46508.1 - 0.89 9.7 8.4 1.6 8.8 0.1 3.2 3 0 0 3 3 3 0 Uncharacterized Strongylid L4 protein RsbRD_N PF14361.6 EST46509.1 - 0.018 15.7 0.9 2.3 8.9 0.1 2.6 2 0 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain FliH PF02108.16 EST46509.1 - 0.02 15.0 4.2 0.15 12.1 0.3 3.1 3 1 0 3 3 3 0 Flagellar assembly protein FliH DUF3567 PF12091.8 EST46509.1 - 0.028 14.5 0.3 0.63 10.2 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3567) CT_C_D PF02682.16 EST46509.1 - 0.087 12.6 0.6 0.25 11.1 0.2 1.9 2 0 0 2 2 2 0 Carboxyltransferase domain, subdomain C and D Ribonuc_P_40 PF08584.11 EST46511.1 - 0.2 10.9 9.1 0.014 14.7 3.7 1.7 2 0 0 2 2 2 0 Ribonuclease P 40kDa (Rpp40) subunit Sigma54_activ_2 PF14532.6 EST46512.1 - 0.6 10.2 4.7 0.23 11.6 0.4 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain VSP PF03302.13 EST46513.1 - 0.0016 17.3 33.9 0.0016 17.3 33.9 6.9 1 1 6 7 7 7 2 Giardia variant-specific surface protein TMEM154 PF15102.6 EST46513.1 - 0.033 14.1 0.5 0.06 13.2 0.5 1.3 1 0 0 1 1 1 0 TMEM154 protein family BatD PF13584.6 EST46513.1 - 0.34 9.7 0.0 0.45 9.3 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance EphA2_TM PF14575.6 EST46513.1 - 2.6 9.0 5.5 0.91 10.4 1.1 2.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain NOG1_N PF17835.1 EST46514.1 - 2e-58 196.9 1.2 2e-58 196.9 1.2 1.8 2 0 0 2 2 2 1 NOG1 N-terminal helical domain MMR_HSR1 PF01926.23 EST46514.1 - 4.1e-17 62.3 0.0 1.3e-16 60.7 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase NOG1 PF06858.14 EST46514.1 - 2.2e-15 56.2 0.2 5.7e-15 54.8 0.2 1.8 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 EST46514.1 - 3.4e-13 49.4 0.3 1.4e-12 47.4 0.6 1.9 2 0 0 2 2 2 1 NOGCT (NUC087) domain FeoB_N PF02421.18 EST46514.1 - 7.1e-10 38.6 0.1 3e-09 36.6 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.16 EST46514.1 - 1.1e-06 28.2 0.1 2.3e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 EST46514.1 - 7.9e-05 22.8 3.7 0.0045 17.1 0.0 3.0 2 1 1 3 3 3 2 Dynamin family AAA_23 PF13476.6 EST46514.1 - 0.001 19.6 3.7 0.062 13.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain Ras PF00071.22 EST46514.1 - 0.0014 18.2 0.0 0.0053 16.4 0.0 2.1 1 1 0 1 1 1 1 Ras family AAA_16 PF13191.6 EST46514.1 - 0.0033 17.8 0.0 0.019 15.3 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain cobW PF02492.19 EST46514.1 - 0.0033 17.0 0.2 2.1 7.9 0.0 2.6 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 EST46514.1 - 0.0036 17.2 0.0 0.76 9.7 0.0 2.7 2 1 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 EST46514.1 - 0.0085 16.6 0.1 0.043 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain SRPRB PF09439.10 EST46514.1 - 0.011 15.2 0.0 0.021 14.3 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.6 EST46514.1 - 0.06 13.6 0.0 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF3552 PF12072.8 EST46515.1 - 0.33 10.3 11.4 0.44 9.9 11.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Exonuc_VII_L PF02601.15 EST46515.1 - 2.3 7.7 14.0 2.6 7.5 14.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit PUF PF00806.19 EST46516.1 - 1.7e-26 90.3 20.6 4.3e-07 29.3 0.1 7.6 7 0 0 7 7 7 6 Pumilio-family RNA binding repeat DUF2054 PF10218.9 EST46516.1 - 0.32 11.1 6.1 0.053 13.6 1.7 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2054) CPL PF08144.11 EST46516.1 - 0.46 10.8 6.8 4.3 7.7 1.2 3.5 2 2 0 2 2 2 0 CPL (NUC119) domain SGS PF05002.15 EST46518.1 - 5e-08 32.9 2.9 5e-08 32.9 2.9 1.6 2 0 0 2 2 2 1 SGS domain DUF3568 PF12092.8 EST46518.1 - 0.24 11.5 2.3 0.48 10.5 2.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3568) ANAPC3 PF12895.7 EST46519.1 - 0.018 15.2 1.4 1.1 9.6 0.1 3.5 2 2 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EST46519.1 - 0.019 15.7 0.5 3.4 8.7 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat PhoU PF01895.19 EST46519.1 - 0.058 13.9 0.1 0.28 11.7 0.1 2.2 1 0 0 1 1 1 0 PhoU domain TPR_16 PF13432.6 EST46519.1 - 0.13 12.9 0.3 0.63 10.7 0.0 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_C8 PF03569.13 EST46520.1 - 0.021 14.3 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase family C8 ATG16 PF08614.11 EST46520.1 - 0.84 9.8 44.2 0.096 12.9 16.7 3.2 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) AAA_13 PF13166.6 EST46520.1 - 1 7.9 48.9 1.7 7.2 9.0 2.1 1 1 1 2 2 2 0 AAA domain HAP1_N PF04849.13 EST46520.1 - 6.5 5.9 51.9 0.059 12.6 13.9 3.0 1 1 2 3 3 3 0 HAP1 N-terminal conserved region MORN PF02493.20 EST46521.1 - 6.1e-20 69.9 81.3 0.062 13.2 0.2 20.8 25 0 0 25 25 25 13 MORN repeat DUF4200 PF13863.6 EST46522.1 - 0.0031 17.9 8.1 0.0031 17.9 8.1 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4200) Spc7 PF08317.11 EST46522.1 - 0.0038 16.2 17.4 0.0049 15.8 17.4 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein HMMR_N PF15905.5 EST46522.1 - 0.015 14.8 19.7 0.017 14.6 19.7 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal TPR_MLP1_2 PF07926.12 EST46522.1 - 0.026 14.6 20.4 0.28 11.3 9.0 2.2 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Syntaxin-6_N PF09177.11 EST46522.1 - 0.15 12.6 8.7 0.21 12.2 8.0 1.6 1 1 0 1 1 1 0 Syntaxin 6, N-terminal HemX PF04375.14 EST46522.1 - 0.35 10.1 21.0 0.14 11.5 17.6 1.7 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF3450 PF11932.8 EST46522.1 - 0.59 9.4 19.5 0.33 10.2 17.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Fib_alpha PF08702.10 EST46522.1 - 0.66 10.2 18.8 1.4 9.1 6.0 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Exonuc_VII_L PF02601.15 EST46522.1 - 2.1 7.8 14.1 2.9 7.4 14.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit FAM76 PF16046.5 EST46522.1 - 3 7.1 14.1 4.3 6.6 14.1 1.3 1 0 0 1 1 1 0 FAM76 protein YjcZ PF13990.6 EST46522.1 - 5.2 6.4 11.8 1.8 7.9 2.0 2.0 1 1 1 2 2 2 0 YjcZ-like protein DUF4665 PF15679.5 EST46522.1 - 8 7.1 12.8 0.46 11.1 4.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4665) Ribosomal_S13_N PF08069.12 EST46523.1 - 2.9e-20 72.1 0.0 5e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 EST46523.1 - 2.7e-12 46.7 0.1 3.9e-12 46.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 DUF5340 PF17275.2 EST46523.1 - 0.025 14.7 0.0 1.7 8.8 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5340) DNA_pol3_delta2 PF13177.6 EST46525.1 - 0.041 13.7 0.2 0.052 13.3 0.2 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit CH PF00307.31 EST46526.1 - 6.9e-20 71.3 10.6 1.3e-09 38.1 3.0 2.9 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EST46526.1 - 4.2e-05 23.3 4.5 0.0024 17.6 0.1 4.2 3 1 0 3 3 3 1 CAMSAP CH domain Aminopep PF10023.9 EST46526.1 - 0.0055 16.1 2.6 0.0055 16.1 2.6 2.0 1 1 1 2 2 2 1 Putative aminopeptidase CH_2 PF06294.11 EST46526.1 - 0.17 12.0 12.9 0.061 13.5 3.6 4.1 4 2 0 4 4 4 0 CH-like domain in sperm protein TFIIS_M PF07500.14 EST46526.1 - 3.1 8.3 12.7 1.3 9.6 3.0 2.8 1 1 1 2 2 2 0 Transcription factor S-II (TFIIS), central domain Bromodomain PF00439.25 EST46531.1 - 1.5e-15 57.0 0.1 3.3e-15 55.9 0.1 1.6 1 1 0 1 1 1 1 Bromodomain Aa_trans PF01490.18 EST46532.1 - 8.7e-33 113.6 42.0 1.1e-32 113.3 42.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 EST46532.1 - 0.0056 15.6 46.5 0.16 10.7 46.5 2.0 1 1 0 1 1 1 1 Amino acid permease PsbH PF00737.20 EST46532.1 - 0.97 9.2 5.8 0.32 10.8 0.6 2.9 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein TetR_C_27 PF17935.1 EST46533.1 - 0.0036 17.4 0.7 0.066 13.3 0.1 3.0 3 0 0 3 3 3 1 Tetracyclin repressor-like, C-terminal domain Astro_capsid_N PF03115.14 EST46533.1 - 3.3 6.3 6.3 9 4.8 6.3 1.7 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Lipase_3 PF01764.25 EST46534.1 - 4.5e-10 39.5 0.1 9.8e-10 38.5 0.1 1.5 1 0 0 1 1 1 1 Lipase (class 3) BAAT_C PF08840.11 EST46534.1 - 0.06 13.3 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF4894 PF16235.5 EST46535.1 - 0.051 13.9 1.2 0.071 13.5 1.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4894) Zea_mays_MuDR PF05928.11 EST46537.1 - 0.075 12.7 0.1 0.088 12.4 0.1 1.1 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) Nrap_D3 PF17404.2 EST46539.1 - 1.3e-07 31.9 0.9 3.8e-07 30.3 0.0 2.3 2 1 0 2 2 2 1 Nrap protein domain 3 Nrap_D5 PF17406.2 EST46539.1 - 1.9e-06 27.7 0.1 0.21 11.3 0.1 3.4 2 1 0 2 2 2 2 Nrap protein PAP/OAS1-like domain 5 Ig_2 PF13895.6 EST46539.1 - 0.023 15.0 0.0 0.085 13.2 0.0 2.0 1 0 0 1 1 1 0 Immunoglobulin domain DUF2683 PF10884.8 EST46539.1 - 0.088 13.1 1.1 3.1 8.1 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2683) DUF4407 PF14362.6 EST46541.1 - 6.2 6.1 11.0 0.88 8.9 3.6 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) S10_plectin PF03501.15 EST46542.1 - 1.2e-16 60.5 0.2 2.9e-16 59.3 0.2 1.6 1 1 0 1 1 1 1 Plectin/S10 domain Pim PF16765.5 EST46542.1 - 0.068 13.3 0.0 0.092 12.9 0.0 1.3 1 0 0 1 1 1 0 Pesticin immunity protein Fibrillarin PF01269.17 EST46543.1 - 3.7e-95 317.3 0.0 4.3e-95 317.1 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 EST46543.1 - 0.00013 21.7 0.0 0.00021 21.0 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 EST46543.1 - 0.0005 19.9 0.0 0.00068 19.4 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 EST46543.1 - 0.093 12.8 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 EST46543.1 - 0.15 11.7 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Rubella_Capsid PF05750.11 EST46543.1 - 1.1 8.7 17.3 4.1 6.9 16.2 2.0 2 0 0 2 2 2 0 Rubella capsid protein Ectoine_synth PF06339.12 EST46544.1 - 0.17 12.1 1.0 0.86 9.8 0.2 2.4 2 0 0 2 2 2 0 Ectoine synthase GpcrRhopsn4 PF10192.9 EST46545.1 - 1.2e-18 67.5 26.9 1.7e-18 67.0 26.9 1.2 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Flexi_CP PF00286.20 EST46545.1 - 0.032 14.2 0.3 0.17 11.8 0.0 2.1 1 1 2 3 3 3 0 Viral coat protein DUF4369 PF14289.6 EST46545.1 - 0.068 13.7 0.4 0.49 10.9 0.0 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4369) MHYT PF03707.16 EST46545.1 - 1.3 9.3 7.3 3.1 8.0 0.2 3.6 3 1 0 3 3 3 0 Bacterial signalling protein N terminal repeat Helicase_C PF00271.31 EST46550.1 - 5.7e-11 42.7 7.5 1.1e-10 41.9 0.1 4.1 2 1 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 EST46550.1 - 7.3e-09 35.6 1.6 1.9e-08 34.3 0.1 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase HA2 PF04408.23 EST46550.1 - 0.001 19.3 0.6 0.0031 17.8 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) AAA_22 PF13401.6 EST46550.1 - 0.022 15.0 0.1 0.083 13.2 0.1 2.0 1 0 0 1 1 1 0 AAA domain Mg_trans_NIPA PF05653.14 EST46551.1 - 3.6e-22 78.8 22.2 4.5e-22 78.5 22.2 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA DctQ PF04290.12 EST46551.1 - 4.3e-05 23.4 6.5 0.00037 20.4 5.1 2.6 2 0 0 2 2 2 1 Tripartite ATP-independent periplasmic transporters, DctQ component EamA PF00892.20 EST46551.1 - 0.00031 20.9 1.7 0.00031 20.9 1.7 3.3 2 1 1 3 3 3 1 EamA-like transporter family HTH_51 PF18558.1 EST46551.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain MRAP PF15183.6 EST46551.1 - 0.3 11.1 4.1 1 9.3 0.0 2.6 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family DUF370 PF04025.12 EST46552.1 - 0.018 15.1 0.8 0.055 13.6 0.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF370) Rad51 PF08423.11 EST46553.1 - 1.4e-103 345.6 0.4 3e-103 344.6 0.1 1.6 2 0 0 2 2 2 1 Rad51 RecA PF00154.21 EST46553.1 - 6.1e-10 39.0 0.2 8.7e-10 38.5 0.2 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 EST46553.1 - 8.1e-09 35.2 0.0 2.1e-08 33.8 0.0 1.8 1 1 0 1 1 1 1 KaiC Arm_2 PF04826.13 EST46553.1 - 0.00023 20.7 0.1 0.00038 20.0 0.1 1.3 1 0 0 1 1 1 1 Armadillo-like HHH_5 PF14520.6 EST46553.1 - 0.00063 20.3 3.0 0.0012 19.4 1.8 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain AAA_22 PF13401.6 EST46553.1 - 0.0073 16.6 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 EST46553.1 - 0.049 13.0 0.0 0.16 11.3 0.0 1.8 1 1 0 1 1 1 0 Bacterial TniB protein Gly_radical PF01228.21 EST46555.1 - 0.0013 19.3 0.9 0.26 11.8 0.2 2.3 2 0 0 2 2 2 2 Glycine radical Mating_N PF12731.7 EST46555.1 - 0.0029 17.7 0.2 0.015 15.4 0.1 2.2 2 0 0 2 2 2 1 Mating-type protein beta 1 Lyase_aromatic PF00221.19 EST46555.1 - 0.14 10.8 1.4 0.22 10.1 1.4 1.4 1 1 0 1 1 1 0 Aromatic amino acid lyase DUF4493 PF14900.6 EST46556.1 - 0.022 14.6 0.9 0.042 13.7 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4493) P22_portal PF16510.5 EST46557.1 - 0.086 11.4 0.7 0.11 11.0 0.6 1.3 1 1 0 1 1 1 0 Phage P22-like portal protein DUF4410 PF14366.6 EST46558.1 - 0.077 12.9 0.7 0.14 12.1 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4410) Peptidase_C16 PF01831.17 EST46558.1 - 0.13 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase C16 family Nrf1_DNA-bind PF10491.9 EST46558.1 - 8.5 6.0 9.5 1.7 8.3 3.9 2.3 2 1 1 3 3 3 0 NLS-binding and DNA-binding and dimerisation domains of Nrf1 DUF2203 PF09969.9 EST46558.1 - 8.7 7.1 8.9 2.4 8.9 5.2 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF4446 PF14584.6 EST46559.1 - 0.18 11.8 4.2 0.19 11.7 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Tup_N PF08581.10 EST46559.1 - 0.4 11.0 8.8 1.8 8.9 3.6 2.3 1 1 1 2 2 2 0 Tup N-terminal MatE PF01554.18 EST46560.1 - 3.3e-09 36.6 34.2 9.8e-08 31.8 14.5 2.4 2 0 0 2 2 2 2 MatE WD40 PF00400.32 EST46561.1 - 0.18 12.7 0.6 7.2 7.7 0.0 3.8 4 0 0 4 4 4 0 WD domain, G-beta repeat ATP_bind_1 PF03029.17 EST46562.1 - 1.4e-46 159.2 0.0 2e-46 158.8 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 EST46562.1 - 7.2e-06 26.2 0.0 1.6e-05 25.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 EST46562.1 - 8.3e-05 22.2 0.0 0.015 14.9 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 EST46562.1 - 0.00012 21.7 0.2 0.088 12.3 0.1 2.7 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 EST46562.1 - 0.00056 19.7 0.0 0.0021 17.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EST46562.1 - 0.00079 19.8 0.0 0.0018 18.7 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 EST46562.1 - 0.0011 18.2 0.0 0.0023 17.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain RsgA_GTPase PF03193.16 EST46562.1 - 0.0014 18.6 1.1 0.9 9.4 0.0 3.0 3 1 0 4 4 3 2 RsgA GTPase NACHT PF05729.12 EST46562.1 - 0.0076 16.2 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 EST46562.1 - 0.01 16.4 0.1 0.055 14.0 0.0 2.3 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EST46562.1 - 0.022 14.7 0.1 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 EST46562.1 - 0.028 14.4 1.2 0.1 12.6 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EST46562.1 - 0.035 14.4 0.0 0.11 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EST46562.1 - 0.043 14.3 0.1 0.22 12.0 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Viral_helicase1 PF01443.18 EST46562.1 - 0.044 13.5 0.0 0.072 12.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 EST46562.1 - 0.051 13.3 0.0 0.089 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 EST46562.1 - 0.075 12.5 0.2 4.2 6.8 0.0 2.8 3 1 0 3 3 3 0 ADP-ribosylation factor family Roc PF08477.13 EST46562.1 - 0.078 13.2 0.0 0.82 9.9 0.0 2.6 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 EST46562.1 - 0.083 12.6 0.2 0.52 10.1 0.0 2.4 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 EST46562.1 - 0.12 12.5 0.0 0.47 10.6 0.0 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA PF00004.29 EST46562.1 - 0.15 12.5 0.0 0.33 11.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SIR2 PF02146.17 EST46562.1 - 0.15 12.0 0.3 0.26 11.2 0.3 1.3 1 0 0 1 1 1 0 Sir2 family AAA_19 PF13245.6 EST46562.1 - 0.15 12.4 0.4 0.24 11.8 0.4 1.9 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EST46562.1 - 0.19 12.2 0.5 0.48 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Myb_DNA-bind_3 PF12776.7 EST46564.1 - 0.093 13.7 0.2 0.36 11.8 0.0 2.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain F5_F8_type_C PF00754.25 EST46567.1 - 1.3e-06 28.6 0.0 1.6e-06 28.3 0.0 1.0 1 0 0 1 1 1 1 F5/8 type C domain Gly_transf_sug PF04488.15 EST46567.1 - 0.011 16.3 0.0 0.023 15.3 0.0 1.6 1 1 0 1 1 1 0 Glycosyltransferase sugar-binding region containing DXD motif ANAPC10 PF03256.16 EST46567.1 - 0.036 13.7 0.0 0.041 13.5 0.0 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) DUF2914 PF11141.8 EST46567.1 - 0.084 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) XRCC1_N PF01834.16 EST46567.1 - 0.094 12.7 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 XRCC1 N terminal domain Cyt-b5 PF00173.28 EST46568.1 - 1.3e-07 31.6 0.0 1.9e-07 31.1 0.0 1.5 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ubiquitin PF00240.23 EST46568.1 - 0.0056 16.4 0.0 0.02 14.6 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family Peptidase_M9_N PF08453.10 EST46568.1 - 0.025 14.3 0.0 0.069 12.9 0.0 1.7 2 0 0 2 2 2 0 Peptidase family M9 N-terminal Rad60-SLD PF11976.8 EST46568.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2028 PF09667.10 EST46569.1 - 0.02 14.8 2.1 0.022 14.7 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF2028) DUF1192 PF06698.11 EST46569.1 - 0.082 13.0 0.1 22 5.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Pkinase PF00069.25 EST46571.1 - 5.9e-49 166.8 0.7 5.9e-49 166.8 0.7 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST46571.1 - 2.6e-20 72.8 0.3 3.5e-20 72.4 0.3 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EST46571.1 - 1.2e-08 34.7 0.5 3.3e-08 33.2 0.5 1.8 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.6 EST46571.1 - 0.00016 21.3 5.7 0.016 14.8 0.2 3.2 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EST46571.1 - 0.0028 17.0 0.1 0.0058 16.0 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EST46571.1 - 0.0095 15.5 1.4 0.017 14.7 1.4 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 EST46571.1 - 0.017 13.9 0.0 0.023 13.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EST46571.1 - 0.025 14.5 0.0 0.05 13.5 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family NAAA-beta PF15508.6 EST46573.1 - 0.055 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase WD40 PF00400.32 EST46575.1 - 1.8e-06 28.5 3.3 1.1 10.2 0.0 6.4 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EST46575.1 - 7.6e-06 26.1 0.0 1.5 9.2 0.0 4.8 3 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Arf PF00025.21 EST46576.1 - 2.6e-55 186.6 0.0 2.9e-55 186.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EST46576.1 - 8.6e-12 44.9 0.0 1.1e-11 44.6 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EST46576.1 - 8.1e-11 41.7 0.5 8.3e-08 31.8 0.1 2.5 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EST46576.1 - 7.4e-10 38.6 0.0 9.1e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EST46576.1 - 1.7e-09 37.8 0.0 2.2e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 EST46576.1 - 1.8e-09 37.8 0.0 3.6e-09 36.9 0.0 1.4 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EST46576.1 - 0.00013 21.4 0.0 0.00015 21.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EST46576.1 - 0.0019 17.8 0.0 0.33 10.5 0.0 2.0 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EST46576.1 - 0.027 14.4 0.3 0.2 11.6 0.1 2.0 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 EST46576.1 - 0.087 13.3 0.1 0.14 12.7 0.1 1.5 1 1 0 1 1 1 0 ABC transporter TF_Zn_Ribbon PF08271.12 EST46577.1 - 3.2e-05 23.3 0.1 6.6e-05 22.3 0.1 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Lar_restr_allev PF14354.6 EST46577.1 - 0.024 15.0 1.1 0.024 15.0 1.1 2.3 1 1 1 2 2 2 0 Restriction alleviation protein Lar Tup_N PF08581.10 EST46577.1 - 0.072 13.4 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 Tup N-terminal Rpr2 PF04032.16 EST46577.1 - 1.1 9.6 4.7 0.59 10.5 1.7 2.1 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain FYVE PF01363.21 EST46577.1 - 2.9 8.1 8.9 0.32 11.2 3.5 2.2 2 0 0 2 2 2 0 FYVE zinc finger zf-ribbon_3 PF13248.6 EST46577.1 - 4.9 6.7 7.2 15 5.2 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.7 EST46577.1 - 6 7.0 10.2 1.5 8.9 5.5 2.5 2 1 0 2 2 2 0 Double zinc ribbon CRAL_TRIO PF00650.20 EST46578.1 - 0.095 12.4 0.3 0.27 10.9 0.2 1.8 2 0 0 2 2 2 0 CRAL/TRIO domain DUF3149 PF11346.8 EST46578.1 - 8.1 6.2 9.3 22 4.8 9.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Dynein_light PF01221.18 EST46579.1 - 6.9e-26 90.4 0.1 7.9e-26 90.2 0.1 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.18 EST46579.1 - 0.0028 18.3 0.0 0.0033 18.0 0.0 1.2 1 0 0 1 1 1 1 Ground-like domain DUF3646 PF12362.8 EST46579.1 - 0.14 12.5 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III gamma and tau subunits C terminal KASH_CCD PF14662.6 EST46581.1 - 0.0073 16.2 51.7 0.42 10.4 21.7 3.2 1 1 1 2 2 2 2 Coiled-coil region of CCDC155 or KASH ANAPC_CDC26 PF10471.9 EST46581.1 - 0.042 14.7 0.8 0.042 14.7 0.8 4.1 4 1 1 5 5 5 0 Anaphase-promoting complex APC subunit CDC26 ZapB PF06005.12 EST46581.1 - 0.046 14.2 1.7 0.046 14.2 1.7 5.9 3 2 3 6 6 6 0 Cell division protein ZapB DUF948 PF06103.11 EST46581.1 - 4.2 7.7 12.6 1.7 9.0 0.2 3.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) CpXC PF14353.6 EST46581.1 - 4.3 7.4 8.3 0.27 11.3 0.8 2.5 2 1 0 2 2 2 0 CpXC protein SdpA PF17418.2 EST46582.1 - 0.11 12.4 0.3 0.29 11.0 0.1 1.8 2 0 0 2 2 2 0 Sporulation delaying protein SdpA SlyX PF04102.12 EST46582.1 - 0.67 10.6 0.1 0.67 10.6 0.1 5.8 4 2 3 7 7 7 0 SlyX Chrome_Resist PF09828.9 EST46582.1 - 1.4 9.4 3.9 29 5.1 0.3 3.0 2 1 1 3 3 3 0 Chromate resistance exported protein LPP PF04728.13 EST46582.1 - 2.6 8.5 12.5 2.3 8.7 0.4 4.4 3 1 1 4 4 4 0 Lipoprotein leucine-zipper TIR-like PF10137.9 EST46582.1 - 5.7 6.9 6.3 2.5 8.1 0.0 3.1 4 0 0 4 4 4 0 Predicted nucleotide-binding protein containing TIR-like domain SAVED PF18145.1 EST46583.1 - 0.013 15.3 0.5 0.024 14.4 0.5 1.4 1 1 0 1 1 1 0 SMODS-associated and fused to various effectors sensor domain FAP206 PF12018.8 EST46583.1 - 0.024 14.2 1.1 0.041 13.4 1.1 1.4 1 1 0 1 1 1 0 Domain of unknown function Syntaxin-6_N PF09177.11 EST46583.1 - 0.032 14.8 0.2 0.048 14.2 0.2 1.3 1 0 0 1 1 1 0 Syntaxin 6, N-terminal SKA2 PF16740.5 EST46583.1 - 0.048 13.4 0.7 0.36 10.6 0.7 2.0 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 2 Maf1 PF09174.10 EST46584.1 - 0.05 13.8 1.6 0.068 13.3 1.6 1.1 1 0 0 1 1 1 0 Maf1 regulator RTP801_C PF07809.11 EST46585.1 - 0.029 14.2 2.7 0.086 12.7 0.2 2.8 3 0 0 3 3 3 0 RTP801 C-terminal region Rav1p_C PF12234.8 EST46586.1 - 5.7e-19 68.0 0.6 5.7e-19 68.0 0.6 2.0 2 0 0 2 2 2 1 RAVE protein 1 C terminal UPF0113_N PF17833.1 EST46586.1 - 0.1 13.2 1.8 0.78 10.3 0.2 3.4 2 0 0 2 2 2 0 UPF0113 Pre-PUA domain RAMPs PF03787.15 EST46587.1 - 0.0029 17.7 0.1 0.0037 17.3 0.1 1.1 1 0 0 1 1 1 1 RAMP superfamily Gp_dh_N PF00044.24 EST46588.1 - 1.5e-36 124.8 0.1 1.9e-36 124.5 0.1 1.1 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 EST46588.1 - 0.0048 17.0 0.5 0.011 15.9 0.5 1.8 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 EST46588.1 - 0.057 12.8 0.1 0.077 12.3 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 EST46589.1 - 2.9e-40 137.5 0.6 3.2e-40 137.3 0.6 1.0 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DUF4358 PF14270.6 EST46589.1 - 0.041 14.2 0.1 0.058 13.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4358) APG6_N PF17675.1 EST46590.1 - 0.003 18.1 19.8 0.003 18.1 19.8 10.9 1 1 8 10 10 10 2 Apg6 coiled-coil region zf-CCCH_6 PF18585.1 EST46590.1 - 0.056 13.3 0.2 1.1 9.2 0.2 3.5 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Prefoldin_2 PF01920.20 EST46591.1 - 6.4e-07 29.3 5.7 7.5e-07 29.1 5.7 1.1 1 0 0 1 1 1 1 Prefoldin subunit Colicin_E5 PF12106.8 EST46591.1 - 0.054 13.8 0.2 0.11 12.9 0.1 1.6 1 1 0 1 1 1 0 Colicin E5 ribonuclease domain CsbD PF05532.12 EST46591.1 - 0.24 11.3 3.3 4.9 7.1 0.1 2.5 2 0 0 2 2 2 0 CsbD-like Pyr_redox_2 PF07992.14 EST46592.1 - 1.1e-46 159.5 0.0 1.4e-46 159.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EST46592.1 - 3.3e-14 53.2 0.1 3.3e-11 43.6 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EST46592.1 - 2.3e-10 40.2 0.2 3.1e-09 36.5 0.1 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EST46592.1 - 1.2e-08 34.5 0.0 2.1e-06 27.1 0.0 2.6 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_dim PF02852.22 EST46592.1 - 1.7e-08 34.7 0.0 7e-08 32.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 2-Hacid_dh_C PF02826.19 EST46592.1 - 3e-08 33.2 0.0 0.017 14.5 0.0 3.4 2 1 1 3 3 3 3 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 EST46592.1 - 7.5e-07 29.0 0.0 0.016 14.8 0.0 3.3 3 0 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.14 EST46592.1 - 1.1e-06 27.6 0.1 0.29 9.8 0.0 3.8 3 1 1 4 4 4 2 HI0933-like protein NAD_binding_8 PF13450.6 EST46592.1 - 3.5e-05 23.9 0.0 0.024 14.8 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 EST46592.1 - 0.00088 19.2 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 EST46592.1 - 0.0012 18.8 0.0 0.1 12.6 0.0 3.0 2 1 1 3 3 3 1 FAD-NAD(P)-binding TrkA_N PF02254.18 EST46592.1 - 0.0075 16.5 0.0 0.17 12.2 0.0 2.6 2 0 0 2 2 2 1 TrkA-N domain Amino_oxidase PF01593.24 EST46592.1 - 0.0081 15.5 0.0 0.026 13.8 0.0 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DUF2632 PF10943.8 EST46592.1 - 0.018 14.6 0.0 3.3 7.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2632) GIDA PF01134.22 EST46592.1 - 0.027 13.5 0.2 4.6 6.2 0.0 2.9 2 1 1 3 3 3 0 Glucose inhibited division protein A ApbA PF02558.16 EST46592.1 - 0.028 14.1 0.0 0.31 10.7 0.0 2.5 3 0 0 3 3 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 EST46592.1 - 0.029 14.8 0.3 1.1 9.7 0.0 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding ThiF PF00899.21 EST46592.1 - 0.032 13.6 0.0 0.16 11.3 0.0 2.1 3 0 0 3 3 3 0 ThiF family NAD_Gly3P_dh_N PF01210.23 EST46592.1 - 0.034 14.1 0.0 1.7 8.6 0.0 2.7 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.19 EST46592.1 - 0.06 12.6 0.1 13 4.9 0.0 3.0 2 1 1 3 3 3 0 FAD binding domain Thi4 PF01946.17 EST46592.1 - 0.097 11.9 0.0 8.7 5.5 0.0 2.4 2 0 0 2 2 2 0 Thi4 family F420_oxidored PF03807.17 EST46592.1 - 0.12 13.0 0.0 0.69 10.5 0.0 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_2 PF07992.14 EST46593.1 - 5.3e-46 157.2 0.1 6.5e-46 156.9 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EST46593.1 - 1.3e-13 50.9 0.2 1.3e-13 50.9 0.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EST46593.1 - 2.7e-13 50.3 1.5 2.2e-11 44.1 0.1 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EST46593.1 - 4e-07 29.5 0.0 6.7e-06 25.5 0.0 2.6 2 1 2 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.18 EST46593.1 - 1.1e-06 28.9 1.6 0.00089 19.5 0.1 2.9 3 1 0 3 3 2 2 TrkA-N domain NAD_binding_8 PF13450.6 EST46593.1 - 3.8e-06 27.0 0.1 0.16 12.2 0.0 3.2 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EST46593.1 - 4.6e-06 26.5 0.3 0.43 10.1 0.0 3.8 4 0 0 4 4 4 2 FAD dependent oxidoreductase HI0933_like PF03486.14 EST46593.1 - 1.7e-05 23.8 2.0 1.9 7.1 0.0 4.2 4 0 0 4 4 4 1 HI0933-like protein 2-Hacid_dh_C PF02826.19 EST46593.1 - 2.5e-05 23.7 1.1 0.00018 20.9 0.0 2.5 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_dim PF02852.22 EST46593.1 - 0.00012 22.3 1.7 0.0055 16.9 0.1 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 3HCDH_N PF02737.18 EST46593.1 - 0.00033 20.6 0.0 0.0006 19.7 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 EST46593.1 - 0.00087 18.5 7.4 0.069 12.2 0.4 3.1 2 2 1 3 3 3 2 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EST46593.1 - 0.00089 18.4 0.1 8 5.4 0.0 3.1 2 1 1 3 3 3 0 Lycopene cyclase protein ApbA PF02558.16 EST46593.1 - 0.00098 18.8 0.0 0.0056 16.3 0.0 2.2 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 EST46593.1 - 0.0012 19.3 0.1 0.0078 16.6 0.0 2.2 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.23 EST46593.1 - 0.0079 16.2 0.0 0.081 12.9 0.0 2.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_9 PF13454.6 EST46593.1 - 0.011 15.7 0.2 3.1 7.8 0.0 3.4 3 1 1 4 4 4 0 FAD-NAD(P)-binding Thi4 PF01946.17 EST46593.1 - 0.015 14.5 0.1 3.3 6.9 0.0 2.5 2 0 0 2 2 2 0 Thi4 family AlaDh_PNT_C PF01262.21 EST46593.1 - 0.016 14.5 1.2 0.41 9.9 0.0 2.7 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 EST46593.1 - 0.018 15.1 0.6 0.54 10.3 0.0 2.8 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase XdhC_C PF13478.6 EST46593.1 - 0.025 15.1 0.1 0.056 14.0 0.0 1.7 2 0 0 2 2 1 0 XdhC Rossmann domain UDPG_MGDP_dh_N PF03721.14 EST46593.1 - 0.028 14.0 0.2 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 EST46593.1 - 0.042 14.4 1.2 0.12 13.0 0.1 2.3 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.9 EST46593.1 - 0.054 13.3 0.1 0.35 10.7 0.0 2.3 2 0 0 2 2 2 0 Rossmann-like domain FAD_binding_3 PF01494.19 EST46593.1 - 0.18 11.0 0.2 10 5.3 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Metallophos PF00149.28 EST46594.1 - 1.2e-24 87.9 0.0 1.7e-24 87.5 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EST46594.1 - 0.047 13.9 0.0 0.083 13.1 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain SurA_N_2 PF13623.6 EST46594.1 - 0.36 10.7 4.0 1.3 8.9 0.1 2.7 3 0 0 3 3 3 0 SurA N-terminal domain Gp_dh_C PF02800.20 EST46595.1 - 8e-65 217.2 0.0 1.2e-64 216.7 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EST46595.1 - 2.8e-36 123.9 0.4 2.2e-35 121.0 0.1 2.4 3 0 0 3 3 3 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 EST46595.1 - 0.027 14.6 0.3 0.075 13.2 0.3 1.9 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 EST46595.1 - 0.17 11.2 0.2 0.41 10.0 0.1 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FtsJ PF01728.19 EST46596.1 - 8.2e-59 198.7 0.1 2.1e-58 197.4 0.1 1.7 1 0 0 1 1 1 1 FtsJ-like methyltransferase Spb1_C PF07780.12 EST46596.1 - 1.9e-34 119.1 24.7 1.9e-34 119.1 24.7 3.3 3 0 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.8 EST46596.1 - 7.1e-17 61.7 3.9 7.1e-17 61.7 3.9 5.8 3 1 1 5 5 5 1 Domain of unknown function (DUF3381) DUF1823 PF08853.11 EST46596.1 - 0.14 12.4 2.0 0.26 11.5 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1823) HTH_Tnp_Tc5 PF03221.16 EST46596.1 - 7.7 6.6 6.9 9.5 6.3 0.2 3.8 4 0 0 4 4 4 0 Tc5 transposase DNA-binding domain Kelch_5 PF13854.6 EST46598.1 - 0.04 13.9 0.1 4.3 7.4 0.0 2.8 2 0 0 2 2 2 0 Kelch motif PseudoU_synth_1 PF01416.20 EST46599.1 - 9.3e-14 51.8 0.0 2.4e-13 50.5 0.0 1.7 2 0 0 2 2 2 1 tRNA pseudouridine synthase CVNH PF08881.10 EST46600.1 - 0.0014 19.3 1.8 2 9.2 3.2 3.3 1 1 1 2 2 2 2 CVNH domain AlphaC_C PF17480.2 EST46600.1 - 0.005 16.8 2.0 0.016 15.2 2.0 1.9 1 0 0 1 1 1 1 AlphaC C-terminal Syncollin PF15138.6 EST46600.1 - 0.051 13.8 0.5 0.14 12.4 0.5 1.8 1 0 0 1 1 1 0 Syncollin zf-MYST PF17772.1 EST46600.1 - 0.062 12.9 0.2 0.16 11.6 0.2 1.7 1 0 0 1 1 1 0 MYST family zinc finger domain zf-C2H2 PF00096.26 EST46600.1 - 0.29 11.7 4.1 0.63 10.6 4.1 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EST46600.1 - 0.59 11.1 5.5 0.48 11.4 3.6 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 EST46600.1 - 0.68 10.1 11.2 0.081 13.1 1.7 2.6 2 1 0 2 2 2 0 Aberrant zinc-finger Spc7 PF08317.11 EST46600.1 - 5 5.9 35.7 0.37 9.6 20.8 3.0 2 1 0 2 2 2 0 Spc7 kinetochore protein MG4 PF17789.1 EST46601.1 - 1.8 8.8 6.8 0.39 10.9 0.1 3.3 4 0 0 4 4 4 0 Macroglobulin domain MG4 zf-RING_UBOX PF13445.6 EST46602.1 - 9.1e-07 28.8 5.5 9.1e-07 28.8 5.5 4.8 4 2 0 4 4 4 1 RING-type zinc-finger zf-CHY PF05495.12 EST46602.1 - 9.7e-07 29.2 15.8 9.7e-07 29.2 15.8 3.8 1 1 3 4 4 4 1 CHY zinc finger zf-RING_2 PF13639.6 EST46602.1 - 8.5e-06 26.0 3.1 8.5e-06 26.0 3.1 5.7 2 1 3 5 5 5 1 Ring finger domain zf-RING_5 PF14634.6 EST46602.1 - 4.4e-05 23.4 2.3 4.4e-05 23.4 2.3 5.8 4 2 1 5 5 5 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EST46602.1 - 0.00013 21.7 4.1 0.00013 21.7 4.1 5.5 3 1 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) Thoc2 PF11732.8 EST46603.1 - 0.0026 17.8 0.8 0.0069 16.4 0.8 1.7 1 0 0 1 1 1 1 Transcription- and export-related complex subunit DUF612 PF04747.12 EST46603.1 - 4.9 6.1 16.3 5.4 6.0 16.3 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF612 WD40 PF00400.32 EST46604.1 - 2.2e-10 40.9 8.9 0.0015 19.3 0.0 6.8 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EST46604.1 - 8.8e-06 25.9 0.0 2.3 8.6 0.0 4.4 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 EST46604.1 - 0.0015 17.9 0.0 1.6 7.9 0.0 2.7 2 1 0 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit N-terminus mRNA_triPase PF02940.15 EST46605.1 - 1.6e-08 34.6 0.3 2e-07 31.0 0.3 2.2 1 1 0 1 1 1 1 mRNA capping enzyme, beta chain UvrD-helicase PF00580.21 EST46605.1 - 0.054 13.0 0.0 0.063 12.8 0.0 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain FHA PF00498.26 EST46606.1 - 4.3e-18 65.4 0.6 1.3e-17 63.9 0.6 1.9 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EST46606.1 - 1.1e-11 44.9 0.0 3.2e-11 43.4 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain TSC22 PF01166.18 EST46606.1 - 0.00076 19.7 1.7 0.0038 17.5 0.3 2.9 2 0 0 2 2 2 1 TSC-22/dip/bun family MRP-L28 PF09812.9 EST46606.1 - 0.26 11.4 6.6 0.57 10.3 6.6 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 WAC_Acf1_DNA_bd PF10537.9 EST46609.1 - 0.019 15.5 0.1 0.019 15.5 0.1 3.8 3 0 0 3 3 3 0 ATP-utilising chromatin assembly and remodelling N-terminal GhoS PF11080.8 EST46611.1 - 0.06 13.3 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Endoribonuclease GhoS Thioredoxin PF00085.20 EST46613.1 - 3.1e-09 36.7 0.1 5e-09 36.1 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 EST46613.1 - 2e-07 30.2 0.1 2.5e-07 29.9 0.1 1.1 1 0 0 1 1 1 1 Phosducin TraF PF13728.6 EST46613.1 - 0.0076 16.1 0.1 0.012 15.5 0.1 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 EST46613.1 - 0.029 14.8 0.3 0.31 11.5 0.2 2.5 2 1 0 2 2 2 0 Thioredoxin-like domain CBF PF03914.17 EST46614.1 - 0.0066 16.5 0.0 0.017 15.2 0.0 1.8 1 0 0 1 1 1 1 CBF/Mak21 family Mur_ligase_M PF08245.12 EST46616.1 - 9.8e-13 48.5 0.0 2.3e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 Mur ligase middle domain Minor_capsid_1 PF10665.9 EST46616.1 - 0.061 13.5 0.1 0.14 12.4 0.1 1.5 1 0 0 1 1 1 0 Minor capsid protein FHA PF00498.26 EST46618.1 - 0.011 16.1 0.4 0.011 16.1 0.4 4.2 3 3 1 4 4 4 0 FHA domain Dynein_light PF01221.18 EST46619.1 - 3.6e-21 75.3 0.1 4e-21 75.1 0.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 YbaJ PF10757.9 EST46619.1 - 0.053 14.1 0.1 0.069 13.7 0.1 1.2 1 0 0 1 1 1 0 Biofilm formation regulator YbaJ DUF3490 PF11995.8 EST46620.1 - 0.012 15.4 2.4 0.015 15.1 1.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3490) Glyoxalase PF00903.25 EST46620.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Alph_Pro_TM PF09608.10 EST46622.1 - 0.089 12.6 1.0 0.11 12.3 1.0 1.1 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) AAA_23 PF13476.6 EST46623.1 - 0.25 11.8 6.8 0.28 11.6 6.8 1.1 1 0 0 1 1 1 0 AAA domain SKA2 PF16740.5 EST46625.1 - 0.0081 15.9 5.1 0.011 15.4 0.8 2.5 2 0 0 2 2 2 1 Spindle and kinetochore-associated protein 2 MutS_IV PF05190.18 EST46625.1 - 0.36 11.2 3.4 0.75 10.2 1.1 2.6 2 2 0 2 2 2 0 MutS family domain IV Myc-LZ PF02344.15 EST46625.1 - 0.59 10.3 5.3 13 6.0 0.2 3.6 2 1 1 3 3 3 0 Myc leucine zipper domain FGGY_N PF00370.21 EST46626.1 - 1.8e-32 112.8 0.1 2.6e-32 112.3 0.1 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 EST46626.1 - 1.2e-12 48.0 0.3 1.1e-09 38.4 0.1 2.2 1 1 1 2 2 2 2 FGGY family of carbohydrate kinases, C-terminal domain Helicase_C_2 PF13307.6 EST46627.1 - 5.4e-44 150.4 0.0 1.5e-43 148.9 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 EST46627.1 - 6.4e-25 87.8 1.9 6.4e-25 87.8 1.9 3.1 3 0 0 3 3 3 1 DEAD_2 ResIII PF04851.15 EST46627.1 - 0.028 14.4 11.9 0.32 11.0 0.4 3.7 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit Brix PF04427.18 EST46628.1 - 1.4e-18 67.7 0.7 9.6e-18 65.0 0.0 2.2 1 1 1 2 2 2 1 Brix domain AAA_33 PF13671.6 EST46628.1 - 0.056 13.6 0.9 0.6 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain PAP_central PF04928.17 EST46629.1 - 4e-19 68.6 0.1 1.5e-18 66.7 0.1 1.8 1 1 0 1 1 1 1 Poly(A) polymerase central domain NTP_transf_2 PF01909.23 EST46629.1 - 9.1e-06 25.9 0.1 3.5e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 Nucleotidyltransferase domain AAA_3 PF07726.11 EST46630.1 - 0.048 13.5 0.3 0.48 10.3 0.1 2.7 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) ubiquitin PF00240.23 EST46631.1 - 7.6e-06 25.6 0.7 7.6e-06 25.6 0.7 1.9 2 0 0 2 2 2 1 Ubiquitin family NAM-associated PF14303.6 EST46631.1 - 0.39 11.4 9.0 0.095 13.4 3.8 2.0 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain PknG_rubred PF16919.5 EST46631.1 - 2.7 8.1 7.1 0.75 10.0 4.0 1.7 2 0 0 2 2 2 0 Protein kinase G rubredoxin domain AhpC-TSA PF00578.21 EST46632.1 - 1.5e-30 105.7 0.0 1.9e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EST46632.1 - 5.7e-11 42.3 0.0 8.9e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EST46632.1 - 8.4e-09 35.1 0.2 2.3e-08 33.7 0.2 1.8 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin PHP PF02811.19 EST46633.1 - 1.8e-07 31.6 0.1 2.6e-07 31.1 0.1 1.4 1 1 0 1 1 1 1 PHP domain DUF809 PF05663.11 EST46633.1 - 0.0089 16.2 0.3 0.024 14.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF809) DUF3604 PF12228.8 EST46633.1 - 0.16 10.4 0.1 0.23 9.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3604) E2_bind PF08825.10 EST46635.1 - 0.044 13.9 0.0 0.053 13.7 0.0 1.1 1 0 0 1 1 1 0 E2 binding domain AMIN PF11741.8 EST46636.1 - 0.013 15.7 1.8 0.4 10.8 0.4 2.5 2 1 0 2 2 2 0 AMIN domain KAP PF05804.12 EST46638.1 - 2.8e-45 154.7 30.9 2.3e-40 138.5 15.3 4.1 3 1 1 4 4 4 4 Kinesin-associated protein (KAP) RICTOR_M PF14666.6 EST46638.1 - 0.027 14.2 1.0 0.16 11.8 0.2 2.7 2 1 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain CTK3 PF12243.8 EST46638.1 - 0.24 11.4 2.9 0.5 10.4 0.9 2.7 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 TnpV PF14198.6 EST46638.1 - 2.6 8.0 8.2 0.52 10.3 0.7 3.2 3 0 0 3 3 3 0 Transposon-encoded protein TnpV Cellulase PF00150.18 EST46639.1 - 9e-06 25.3 0.1 1.7e-05 24.4 0.1 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TrmB PF01978.19 EST46641.1 - 0.12 12.3 0.0 6 6.8 0.0 2.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB NAPRTase_N PF17767.1 EST46641.1 - 0.27 11.6 4.2 0.95 9.9 4.2 2.0 1 1 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain DUF3347 PF11827.8 EST46642.1 - 0.98 9.6 5.0 1.2 9.3 5.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) SHIPPO-rpt PF07004.12 EST46643.1 - 4.2e-09 36.9 21.0 0.0041 18.0 0.1 6.4 5 1 0 5 5 5 4 Sperm-tail PG-rich repeat DUF3324 PF11797.8 EST46643.1 - 5.4e-05 23.2 0.8 0.045 13.7 0.1 2.8 2 2 0 2 2 2 2 Protein of unknown function C-terminal (DUF3324) DUF4399 PF14347.6 EST46643.1 - 0.13 12.7 0.0 8.6 6.8 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4399) Ribosomal_S10 PF00338.22 EST46644.1 - 1.2e-18 67.1 0.0 1.4e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e GPAT_N PF14829.6 EST46645.1 - 0.099 12.6 1.2 0.3 11.1 1.2 1.9 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal DPCD PF14913.6 EST46646.1 - 9.5e-47 158.8 0.6 1.1e-46 158.6 0.6 1.0 1 0 0 1 1 1 1 DPCD protein family Fib_alpha PF08702.10 EST46647.1 - 0.024 14.8 9.4 0.028 14.6 9.4 1.0 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Plasmid_RAQPRD PF09686.10 EST46647.1 - 0.2 11.9 3.1 0.34 11.2 2.5 1.9 1 1 1 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) SNF2_N PF00176.23 EST46648.1 - 8.3e-33 113.5 4.7 1.5e-32 112.7 4.7 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EST46648.1 - 1.9e-14 53.9 2.9 2.5e-13 50.3 0.0 3.3 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EST46648.1 - 2.1e-09 37.6 1.5 2.1e-09 37.6 1.5 3.5 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EST46648.1 - 4.3e-09 36.0 1.2 1.1e-08 34.6 1.2 1.7 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 EST46648.1 - 0.031 14.5 0.8 0.29 11.4 0.1 2.9 2 1 0 2 2 2 0 AAA domain SWI2_SNF2 PF18766.1 EST46648.1 - 0.11 12.1 0.0 0.11 12.1 0.0 2.9 3 0 0 3 3 3 0 SWI2/SNF2 ATPase Cpn60_TCP1 PF00118.24 EST46649.1 - 5.3e-127 424.4 7.2 6e-127 424.2 7.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Memo PF01875.17 EST46650.1 - 0.00069 18.8 0.0 0.0013 18.0 0.0 1.4 1 0 0 1 1 1 1 Memo-like protein Casein_kappa PF00997.18 EST46650.1 - 0.037 14.1 2.6 0.062 13.4 0.1 2.3 2 0 0 2 2 2 0 Kappa casein Pec_lyase_C PF00544.19 EST46650.1 - 0.061 12.9 0.2 0.11 12.1 0.2 1.4 1 0 0 1 1 1 0 Pectate lyase DUF737 PF05300.11 EST46650.1 - 0.092 13.1 1.9 0.22 11.8 1.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF737) Gal_mutarotas_2 PF13802.6 EST46651.1 - 0.12 12.8 0.4 0.31 11.4 0.4 1.7 1 0 0 1 1 1 0 Galactose mutarotase-like HrpB_C PF08482.10 EST46651.1 - 0.34 11.3 0.0 0.34 11.3 0.0 2.4 3 0 0 3 3 3 0 ATP-dependent helicase C-terminal EF-hand_1 PF00036.32 EST46652.1 - 1.2e-14 52.6 4.2 4.3e-05 22.7 0.0 4.6 4 1 1 5 5 5 3 EF hand EF-hand_6 PF13405.6 EST46652.1 - 1.4e-14 52.7 0.3 2.2e-05 24.0 0.0 4.3 3 2 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 EST46652.1 - 8.1e-13 48.6 0.7 1.4e-07 31.9 0.3 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EST46652.1 - 1.1e-10 41.2 0.9 1.3e-05 24.9 0.0 4.1 2 1 2 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.6 EST46652.1 - 6.6e-09 36.0 0.1 0.0034 17.7 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EST46652.1 - 0.00018 20.8 1.4 0.15 11.6 0.0 3.5 4 0 0 4 4 4 2 EF hand UBA_2 PF08587.11 EST46652.1 - 0.051 13.7 0.1 0.69 10.1 0.0 2.8 4 0 0 4 4 4 0 Ubiquitin associated domain (UBA) PC4 PF02229.16 EST46653.1 - 8.8e-08 31.7 0.8 1.2e-07 31.3 0.8 1.1 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) CopK PF11525.8 EST46653.1 - 0.047 13.3 0.0 0.076 12.6 0.0 1.4 1 1 0 1 1 1 0 Copper resistance protein K NT5C PF06941.12 EST46654.1 - 9.5e-05 22.3 0.3 0.00026 20.9 0.3 1.7 1 1 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) HAD PF12710.7 EST46654.1 - 0.052 13.9 0.1 0.64 10.4 0.1 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF3450 PF11932.8 EST46655.1 - 0.0014 18.0 0.2 0.0029 16.9 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DDHD PF02862.17 EST46655.1 - 0.0054 16.9 3.1 0.0065 16.7 3.1 1.2 1 0 0 1 1 1 1 DDHD domain Baculo_PEP_C PF04513.12 EST46655.1 - 3.4 7.7 16.2 0.076 13.1 4.2 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Collagen PF01391.18 EST46656.1 - 7.8e-07 28.8 26.8 0.018 14.8 16.7 2.4 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) HemolysinCabind PF00353.19 EST46656.1 - 2.8e-05 24.0 8.8 0.3 11.1 0.6 3.5 1 1 5 6 6 6 6 RTX calcium-binding nonapeptide repeat (4 copies) DUF1840 PF08895.11 EST46656.1 - 0.49 10.7 5.5 1.1 9.7 5.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) Tli4_C PF18426.1 EST46656.1 - 1.7 9.0 7.2 0.25 11.6 0.8 2.5 2 1 1 3 3 3 0 Tle cognate immunity protein 4 C-terminal domain PfkB PF00294.24 EST46657.1 - 8.5e-18 64.7 0.0 4e-12 46.1 0.0 2.1 1 1 0 2 2 2 2 pfkB family carbohydrate kinase NTP_transf_7 PF07984.12 EST46657.1 - 0.013 14.7 0.3 0.023 13.9 0.0 1.5 2 0 0 2 2 2 0 Nucleotidyltransferase RNase_PH PF01138.21 EST46658.1 - 5.4e-05 23.7 2.8 0.00059 20.4 1.6 2.5 2 1 0 2 2 2 1 3' exoribonuclease family, domain 1 DUF4764 PF15961.5 EST46658.1 - 0.34 9.5 1.6 0.26 10.0 0.4 1.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4764) EcsB PF05975.12 EST46659.1 - 0.0013 17.7 0.4 0.0014 17.6 0.4 1.0 1 0 0 1 1 1 1 Bacterial ABC transporter protein EcsB UPF0370 PF13980.6 EST46659.1 - 0.036 14.1 0.0 0.063 13.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) Filament PF00038.21 EST46662.1 - 0.00096 18.8 20.4 0.012 15.2 20.4 2.0 1 1 0 1 1 1 1 Intermediate filament protein bZIP_1 PF00170.21 EST46662.1 - 0.0056 16.8 0.6 0.0056 16.8 0.6 2.7 2 1 0 2 2 2 1 bZIP transcription factor Tropomyosin_1 PF12718.7 EST46662.1 - 0.022 14.9 21.2 0.069 13.3 5.7 2.2 1 1 1 2 2 2 0 Tropomyosin like Cas_DxTHG PF09455.10 EST46662.1 - 0.045 13.3 7.7 0.056 13.0 7.7 1.1 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family Phage_TAC_4 PF08748.11 EST46662.1 - 0.1 12.9 6.6 0.087 13.1 5.2 1.7 1 1 1 2 2 2 0 Phage tail assembly chaperone DUF1664 PF07889.12 EST46662.1 - 0.1 12.6 13.7 1.4 9.0 5.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 EST46662.1 - 0.15 12.3 7.5 2 8.7 0.8 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TolA_bind_tri PF16331.5 EST46662.1 - 0.29 11.2 20.6 1.2 9.2 2.1 3.5 2 1 0 2 2 2 0 TolA binding protein trimerisation Pre-PUA PF17832.1 EST46662.1 - 0.32 11.7 2.3 0.81 10.4 1.1 2.0 1 1 0 2 2 2 0 Pre-PUA-like domain IFT20 PF14931.6 EST46662.1 - 0.33 11.1 20.8 3.5 7.8 20.2 2.2 1 1 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 KASH_CCD PF14662.6 EST46662.1 - 0.35 10.7 21.3 0.74 9.6 21.3 1.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH KLRAQ PF10205.9 EST46662.1 - 0.6 10.4 20.5 0.72 10.1 4.3 2.3 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein MPS2 PF17060.5 EST46662.1 - 1.3 8.2 14.1 3.2 6.9 14.0 1.7 1 1 0 1 1 1 0 Monopolar spindle protein 2 UPF0242 PF06785.11 EST46662.1 - 1.4 9.0 24.0 1.7 8.7 9.3 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Mod_r PF07200.13 EST46662.1 - 1.4 9.0 20.6 0.13 12.4 8.2 2.1 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Ly49 PF08391.10 EST46662.1 - 3.5 8.0 10.3 0.72 10.2 4.3 2.1 1 1 2 3 3 3 0 Ly49-like protein, N-terminal region Wx5_PLAF3D7 PF09688.10 EST46662.1 - 3.6 7.6 10.6 0.35 10.9 3.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (Wx5_PLAF3D7) YtxH PF12732.7 EST46662.1 - 3.8 8.1 7.2 5e+02 1.3 7.2 2.8 1 1 0 1 1 1 0 YtxH-like protein APG6_N PF17675.1 EST46662.1 - 3.9 8.0 27.4 6.5 7.3 10.3 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF16 PF01519.16 EST46662.1 - 6.6 7.3 18.8 14 6.2 7.0 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 TMPIT PF07851.13 EST46662.1 - 7 5.8 13.6 6.2 6.0 10.2 1.9 1 1 1 2 2 2 0 TMPIT-like protein YabA PF06156.13 EST46662.1 - 7 7.4 15.2 1 10.0 3.4 2.6 1 1 1 2 2 2 0 Initiation control protein YabA DUF722 PF05263.11 EST46662.1 - 7.4 6.8 13.7 2.1 8.5 2.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF722) DivIC PF04977.15 EST46662.1 - 7.6 6.4 21.7 5.8 6.8 7.1 3.0 1 1 2 3 3 3 0 Septum formation initiator Syntaxin-6_N PF09177.11 EST46662.1 - 7.6 7.2 15.2 6.2 7.4 11.2 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal FAM76 PF16046.5 EST46662.1 - 8.5 5.6 16.5 13 5.0 16.5 1.3 1 1 0 1 1 1 0 FAM76 protein Baculo_PEP_C PF04513.12 EST46662.1 - 9.3 6.3 8.0 8.4 6.4 1.3 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Trimer_CC PF08954.11 EST46663.1 - 0.026 14.1 0.5 0.07 12.7 0.5 1.6 1 0 0 1 1 1 0 Trimerisation motif Ni_hydr_CYTB PF01292.20 EST46663.1 - 0.098 12.3 0.2 0.15 11.6 0.2 1.3 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 TCRP1 PF14944.6 EST46664.1 - 0.018 15.0 0.2 0.023 14.6 0.2 1.1 1 0 0 1 1 1 0 Tongue Cancer Chemotherapy Resistant Protein 1 HAP1_N PF04849.13 EST46665.1 - 2 7.5 39.0 0.022 13.9 10.7 2.4 1 1 1 2 2 2 0 HAP1 N-terminal conserved region Ribosomal_S17 PF00366.20 EST46667.1 - 0.67 10.1 7.3 0.15 12.2 2.1 2.4 1 1 1 2 2 2 0 Ribosomal protein S17 Pyr_redox_2 PF07992.14 EST46668.1 - 0.033 13.4 0.0 0.044 13.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 EST46668.1 - 0.12 12.6 0.1 0.46 10.7 0.1 2.0 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Thoc2 PF11732.8 EST46668.1 - 0.12 12.4 0.1 0.23 11.6 0.1 1.4 1 0 0 1 1 1 0 Transcription- and export-related complex subunit Histone PF00125.24 EST46669.1 - 9.2e-13 48.7 0.4 9.2e-13 48.7 0.4 1.3 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EST46669.1 - 0.008 16.4 0.4 0.014 15.7 0.4 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 EST46669.1 - 0.092 12.9 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Vel1p PF10339.9 EST46669.1 - 0.15 11.4 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Yeast-specific zinc responsive Pyr_redox_2 PF07992.14 EST46670.1 - 0.0063 15.8 0.0 0.0076 15.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thoc2 PF11732.8 EST46670.1 - 0.069 13.2 0.2 0.18 11.9 0.1 1.7 2 0 0 2 2 2 0 Transcription- and export-related complex subunit Sacchrp_dh_NADP PF03435.18 EST46670.1 - 0.084 13.1 0.1 0.33 11.2 0.1 2.0 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EST46670.1 - 0.11 12.6 0.1 0.26 11.3 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Furin-like_2 PF15913.5 EST46671.1 - 6.2e-06 26.3 34.1 0.0035 17.5 21.4 2.8 1 1 1 2 2 2 2 Furin-like repeat, cysteine-rich VSP PF03302.13 EST46671.1 - 0.0071 15.2 40.3 0.043 12.7 40.3 2.0 1 1 0 1 1 1 1 Giardia variant-specific surface protein VSP PF03302.13 EST46672.1 - 1.3e-15 57.1 183.5 1.8e-08 33.7 43.9 6.4 1 1 5 6 6 6 6 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST46672.1 - 0.35 11.0 184.2 0.036 14.2 21.6 11.2 1 1 11 12 12 12 0 Furin-like repeat, cysteine-rich EGF_2 PF07974.13 EST46673.1 - 0.0018 18.6 14.8 0.0018 18.6 14.8 22.1 18 2 2 20 20 20 13 EGF-like domain Syndecan PF01034.20 EST46673.1 - 0.058 13.3 0.4 0.12 12.3 0.4 1.4 1 0 0 1 1 1 0 Syndecan domain RhlB PF12300.8 EST46673.1 - 0.13 12.4 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB MCM PF00493.23 EST46674.1 - 2.1e-58 197.1 0.0 3.5e-58 196.4 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 EST46674.1 - 5.8e-15 55.5 1.0 1.6e-14 54.1 1.0 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 EST46674.1 - 8.3e-13 48.3 0.0 1.8e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 EST46674.1 - 8.9e-09 35.0 0.1 3e-05 23.5 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA PF00004.29 EST46674.1 - 1.4e-06 28.7 0.0 5.7e-06 26.8 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MCM_N PF14551.6 EST46674.1 - 0.00025 21.6 4.7 0.013 16.1 0.0 2.9 2 0 0 2 2 2 1 MCM N-terminal domain Sigma54_activat PF00158.26 EST46674.1 - 0.00038 20.2 0.1 0.093 12.4 0.1 2.8 1 1 0 1 1 1 1 Sigma-54 interaction domain RuvB_N PF05496.12 EST46674.1 - 0.00038 20.2 0.0 0.00082 19.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EST46674.1 - 0.0005 20.1 0.0 0.0024 17.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EST46674.1 - 0.00056 20.5 0.7 0.0024 18.4 0.0 2.3 2 1 1 3 3 3 1 AAA domain AAA_2 PF07724.14 EST46674.1 - 0.00088 19.4 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EST46674.1 - 0.0026 18.0 0.5 0.12 12.7 0.0 3.0 2 1 1 3 3 2 1 AAA domain Sigma54_activ_2 PF14532.6 EST46674.1 - 0.0038 17.4 0.1 0.017 15.2 0.1 2.2 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_24 PF13479.6 EST46674.1 - 0.0085 15.8 0.3 0.038 13.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EST46674.1 - 0.0086 16.2 0.0 0.03 14.4 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 EST46674.1 - 0.0095 16.1 0.1 0.1 12.8 0.0 2.5 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 EST46674.1 - 0.018 15.4 0.1 0.083 13.3 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 EST46674.1 - 0.031 14.0 0.0 0.079 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF4131 PF13567.6 EST46674.1 - 0.076 12.7 0.1 0.34 10.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) AAA_3 PF07726.11 EST46674.1 - 0.08 12.8 0.0 0.27 11.1 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 EST46674.1 - 0.089 12.4 0.1 0.21 11.2 0.1 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 EST46674.1 - 0.13 11.5 0.0 0.67 9.2 0.0 2.0 1 1 1 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 EST46674.1 - 0.16 12.4 0.9 0.96 9.9 0.1 2.7 2 1 0 2 2 2 0 RNA helicase DEAD PF00270.29 EST46674.1 - 0.22 11.3 2.5 0.61 9.8 0.1 2.8 2 2 1 3 3 2 0 DEAD/DEAH box helicase NAC PF01849.18 EST46675.1 - 0.0051 16.8 0.2 0.01 15.8 0.0 1.6 2 0 0 2 2 2 1 NAC domain DUF1967 PF09269.11 EST46675.1 - 0.025 14.5 0.1 0.054 13.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) Glyco_transf_90 PF05686.12 EST46675.1 - 0.031 13.2 0.9 0.032 13.1 0.9 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 90 Myb_DNA-bind_7 PF15963.5 EST46679.1 - 5.3e-05 23.0 0.2 5.6e-05 23.0 0.2 1.1 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 EST46679.1 - 0.0038 17.4 0.0 0.0058 16.8 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Pkinase PF00069.25 EST46681.1 - 1.3e-53 182.1 0.0 1.5e-53 181.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST46681.1 - 7.1e-25 87.8 0.0 9.5e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EST46681.1 - 0.0012 18.3 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EST46681.1 - 0.018 14.4 0.0 0.035 13.5 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Feld-I_B PF09252.10 EST46681.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Allergen Fel d I-B chain Orf78 PF06024.12 EST46683.1 - 4.7 7.6 5.7 0.77 10.1 0.5 2.2 2 0 0 2 2 2 0 Orf78 (ac78) Spec3 PF15795.5 EST46684.1 - 0.72 10.4 9.4 5.3 7.6 7.0 2.3 1 1 1 2 2 2 0 Ectodermal ciliogenesis protein Podoplanin PF05808.11 EST46685.1 - 0.0013 18.8 2.2 0.0013 18.8 2.2 1.6 2 0 0 2 2 2 1 Podoplanin TPPK_C PF12555.8 EST46685.1 - 0.0027 17.7 0.3 0.0044 17.0 0.3 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphokinase C terminal ULD PF16534.5 EST46686.1 - 0.021 14.9 0.6 1.1 9.3 0.1 2.3 1 1 1 2 2 2 0 Ubiquitin-like oligomerisation domain of SATB CYYR1 PF10873.8 EST46687.1 - 0.0084 16.6 2.5 0.011 16.2 2.5 1.1 1 0 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 Herpes_gE PF02480.16 EST46687.1 - 0.016 14.0 0.0 0.018 13.8 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E PARM PF17061.5 EST46689.1 - 0.02 15.0 1.8 0.041 14.0 1.8 1.5 1 0 0 1 1 1 0 PARM Podoplanin PF05808.11 EST46689.1 - 0.52 10.4 6.7 0.98 9.5 6.7 1.4 1 0 0 1 1 1 0 Podoplanin FUN14 PF04930.15 EST46689.1 - 0.52 10.8 0.0 0.52 10.8 0.0 2.6 2 1 0 2 2 2 0 FUN14 family VSP PF03302.13 EST46689.1 - 3.2 6.5 102.6 35 3.1 13.8 5.5 1 1 3 4 4 4 0 Giardia variant-specific surface protein EGF_2 PF07974.13 EST46690.1 - 1.4e-18 67.0 187.8 0.00066 20.0 12.1 13.9 14 2 1 15 15 15 9 EGF-like domain EGF PF00008.27 EST46690.1 - 6.4e-05 23.2 151.2 0.0012 19.1 6.9 13.8 14 2 1 15 15 15 6 EGF-like domain Podoplanin PF05808.11 EST46690.1 - 0.0055 16.8 0.5 0.0097 16.0 0.5 1.3 1 0 0 1 1 1 1 Podoplanin Otopetrin PF03189.13 EST46690.1 - 0.025 13.4 0.1 0.037 12.9 0.1 1.1 1 0 0 1 1 1 0 Otopetrin Syndecan PF01034.20 EST46690.1 - 0.064 13.2 1.6 0.12 12.3 1.6 1.3 1 0 0 1 1 1 0 Syndecan domain Bacteriocin_IIc PF10439.9 EST46690.1 - 0.15 12.2 0.4 0.79 9.9 0.0 2.1 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide EphA2_TM PF14575.6 EST46690.1 - 0.15 12.9 0.3 0.34 11.8 0.3 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Laminin_EGF PF00053.24 EST46690.1 - 1.4 9.1 213.3 0.096 12.8 14.7 11.7 6 3 5 11 11 11 0 Laminin EGF domain MHC_II_beta PF00969.19 EST46691.1 - 0.063 13.4 0.0 0.24 11.5 0.0 1.8 1 1 1 2 2 2 0 Class II histocompatibility antigen, beta domain Mpt_N PF09176.11 EST46692.1 - 0.018 15.2 0.3 3.2 7.9 0.0 3.0 2 2 1 3 3 3 0 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal VSP PF03302.13 EST46693.1 - 1.9e-05 23.7 124.3 0.027 13.4 9.1 4.6 1 1 2 4 4 4 4 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST46693.1 - 0.00031 20.9 9.7 0.00031 20.9 9.7 7.7 1 1 5 7 7 7 2 Furin-like repeat, cysteine-rich Podoplanin PF05808.11 EST46693.1 - 0.092 12.8 0.1 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 Podoplanin Syndecan PF01034.20 EST46693.1 - 0.23 11.4 0.2 0.41 10.6 0.2 1.3 1 0 0 1 1 1 0 Syndecan domain MatE PF01554.18 EST46694.1 - 2.4e-28 98.8 32.0 5.7e-18 65.1 12.0 2.6 2 1 0 2 2 2 2 MatE Polysacc_synt PF01943.17 EST46694.1 - 1.4 8.3 41.4 0.088 12.2 14.5 3.0 2 1 1 3 3 3 0 Polysaccharide biosynthesis protein VSP PF03302.13 EST46695.1 - 0.34 9.7 102.7 4.9 5.9 38.5 4.7 1 1 1 2 2 2 0 Giardia variant-specific surface protein Myb_DNA-bind_6 PF13921.6 EST46698.1 - 6.3e-05 23.1 0.1 0.00011 22.3 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EST46698.1 - 0.00077 19.6 0.1 0.0014 18.8 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain SLIDE PF09111.10 EST46698.1 - 0.0021 18.1 0.3 0.0027 17.7 0.3 1.4 1 1 0 1 1 1 1 SLIDE DUF4065 PF13274.6 EST46698.1 - 0.085 13.7 0.4 0.11 13.3 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4065) IF-2B PF01008.17 EST46699.1 - 6.6e-06 25.5 2.4 9.4e-05 21.7 2.4 2.5 1 1 0 1 1 1 1 Initiation factor 2 subunit family Pox_P4B PF03292.14 EST46699.1 - 0.013 13.8 2.1 0.014 13.7 0.7 1.6 2 0 0 2 2 2 0 Poxvirus P4B major core protein RabGAP-TBC PF00566.18 EST46701.1 - 3.9e-50 170.5 5.3 3.9e-50 170.5 5.3 2.2 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Glyco_hydro_81 PF03639.13 EST46701.1 - 0.01 15.0 1.6 0.34 10.0 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 81 N-terminal domain CSD PF00313.22 EST46701.1 - 0.13 12.2 0.1 0.31 10.9 0.1 1.6 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain Mitovir_RNA_pol PF05919.11 EST46704.1 - 0.13 11.4 3.8 0.17 11.0 3.8 1.1 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase Gp58 PF07902.11 EST46704.1 - 0.68 8.1 15.7 0.4 8.9 13.7 1.5 1 1 0 1 1 1 0 gp58-like protein Ras_bdg_2 PF14847.6 EST46706.1 - 0.01 16.1 0.5 0.016 15.6 0.5 1.4 1 0 0 1 1 1 0 Ras-binding domain of Byr2 Allantoicase PF03561.15 EST46706.1 - 0.043 13.8 0.7 0.067 13.2 0.5 1.3 1 1 0 1 1 1 0 Allantoicase repeat CLIP PF12032.8 EST46706.1 - 0.092 13.0 0.5 0.19 12.1 0.5 1.8 1 1 0 1 1 1 0 Regulatory CLIP domain of proteinases Ly-6_related PF06579.12 EST46706.1 - 0.1 12.9 0.6 0.15 12.3 0.4 1.4 1 1 0 1 1 1 0 Caenorhabditis elegans ly-6-related protein MCPVI PF02993.14 EST46707.1 - 0.038 13.8 0.2 0.071 12.9 0.2 1.6 1 1 0 1 1 1 0 Minor capsid protein VI TPR_19 PF14559.6 EST46708.1 - 0.0025 18.3 0.0 0.49 10.9 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Fungal_TACC PF12709.7 EST46708.1 - 0.1 13.1 8.2 0.12 12.9 2.0 3.0 3 0 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins TPR_14 PF13428.6 EST46708.1 - 0.18 12.7 0.9 16 6.6 0.0 4.0 4 1 1 5 5 5 0 Tetratricopeptide repeat Scramblase PF03803.15 EST46709.1 - 4.9 6.4 6.4 4.2 6.6 0.4 2.9 2 0 0 2 2 2 0 Scramblase EGF_2 PF07974.13 EST46710.1 - 0.00072 19.9 13.5 0.00072 19.9 13.5 21.2 15 4 5 20 20 20 12 EGF-like domain Syndecan PF01034.20 EST46710.1 - 0.0013 18.6 0.2 0.0024 17.7 0.2 1.4 1 0 0 1 1 1 1 Syndecan domain LapA_dom PF06305.11 EST46710.1 - 0.097 12.5 0.9 0.16 11.8 0.9 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Glycophorin_A PF01102.18 EST46710.1 - 0.097 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A Scramblase PF03803.15 EST46711.1 - 4.4 6.5 6.0 2.1 7.6 0.4 2.5 2 0 0 2 2 2 0 Scramblase PAS_7 PF12860.7 EST46714.1 - 0.0006 20.0 0.0 0.00069 19.8 0.0 1.1 1 0 0 1 1 1 1 PAS fold Myb_DNA-binding PF00249.31 EST46716.1 - 5.4e-14 52.1 0.1 1.5e-08 34.7 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST46716.1 - 1.1e-12 48.0 0.0 4.5e-11 42.8 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EST46716.1 - 0.085 13.2 0.1 0.56 10.6 0.0 2.2 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Sporozoite_P67 PF05642.11 EST46717.1 - 3.9 5.4 15.9 2.3 6.2 13.4 1.9 1 1 1 2 2 2 0 Sporozoite P67 surface antigen DUF4464 PF14713.6 EST46719.1 - 2e-76 256.5 3.8 2.2e-76 256.3 3.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) DarA_C PF18789.1 EST46719.1 - 0.075 13.4 0.1 0.26 11.6 0.0 2.0 2 0 0 2 2 2 0 Defence against restriction A C-terminal Myb_DNA-binding PF00249.31 EST46722.1 - 1.2e-05 25.4 0.5 2.2e-05 24.5 0.5 1.6 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST46722.1 - 0.014 15.6 0.3 0.025 14.8 0.3 1.5 1 1 0 1 1 1 0 Myb-like DNA-binding domain RNA_ligase PF09414.10 EST46724.1 - 0.032 14.6 0.2 0.037 14.3 0.2 1.2 1 0 0 1 1 1 0 RNA ligase Myb_DNA-bind_7 PF15963.5 EST46728.1 - 0.099 12.6 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Myb DNA-binding like Symplekin_C PF12295.8 EST46729.1 - 0.012 15.8 0.6 0.031 14.4 0.2 1.8 1 1 1 2 2 2 0 Symplekin tight junction protein C terminal ABC_tran PF00005.27 EST46730.1 - 1.1e-44 152.3 0.0 7.2e-25 88.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EST46730.1 - 6.7e-44 150.6 51.0 5.2e-26 91.9 14.2 2.5 3 0 0 3 3 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EST46730.1 - 1.4e-15 57.4 0.4 6.7e-06 25.7 0.0 3.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EST46730.1 - 6e-05 23.0 0.0 0.25 11.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EST46730.1 - 9.4e-05 22.5 0.0 0.29 11.2 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 EST46730.1 - 0.00057 20.4 0.0 1 9.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 EST46730.1 - 0.0026 17.9 0.9 0.02 15.0 0.0 2.7 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_29 PF13555.6 EST46730.1 - 0.0094 15.7 0.0 1.5 8.6 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EST46730.1 - 0.02 14.7 0.0 8.8 6.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system Sigma54_activat PF00158.26 EST46730.1 - 0.024 14.4 0.0 0.09 12.5 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain Dynamin_N PF00350.23 EST46730.1 - 0.054 13.5 1.2 1.1 9.3 0.1 2.6 2 0 0 2 2 2 0 Dynamin family TrwB_AAD_bind PF10412.9 EST46730.1 - 0.063 12.2 0.2 0.21 10.5 0.1 1.8 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 EST46730.1 - 0.15 12.3 0.2 21 5.4 0.1 3.0 2 1 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EST46730.1 - 0.16 12.2 0.1 4.7 7.5 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 EST46730.1 - 0.17 11.2 0.0 6.6 6.0 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.6 EST46730.1 - 0.17 12.4 0.1 3.6 8.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain Proton_antipo_N PF00662.20 EST46730.1 - 3.6 7.7 6.0 1.1 9.4 0.3 3.1 2 0 0 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus CFAP91 PF14738.6 EST46732.1 - 4.1e-20 72.4 12.8 4.1e-20 72.4 12.8 4.4 4 1 1 5 5 5 1 Cilia- and flagella-associated protein 91 DUF930 PF06059.12 EST46732.1 - 0.016 15.8 1.9 0.038 14.5 0.3 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF930) Peptidase_C1 PF00112.23 EST46733.1 - 4.5e-30 105.4 6.0 8.7e-30 104.4 6.0 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Nucleoside_tran PF01733.18 EST46735.1 - 0.0051 16.2 3.3 0.0063 15.9 3.3 1.1 1 0 0 1 1 1 1 Nucleoside transporter Furin-like_2 PF15913.5 EST46736.1 - 0.4 10.9 50.6 0.043 14.0 13.9 3.9 1 1 3 4 4 4 0 Furin-like repeat, cysteine-rich VSP PF03302.13 EST46742.1 - 2.8e-11 42.9 134.4 1.6e-07 30.6 35.0 5.2 1 1 4 5 5 5 4 Giardia variant-specific surface protein VSP PF03302.13 EST46743.1 - 6.9e-07 28.5 14.7 4.9e-06 25.6 7.3 2.0 1 1 1 2 2 2 2 Giardia variant-specific surface protein CYYR1 PF10873.8 EST46743.1 - 0.027 14.9 4.3 0.034 14.6 4.3 1.3 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 DUF4366 PF14283.6 EST46743.1 - 0.049 13.7 0.0 0.049 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) CD99L2 PF12301.8 EST46743.1 - 0.1 12.9 0.1 0.1 12.9 0.1 1.1 1 0 0 1 1 1 0 CD99 antigen like protein 2 DUF4748 PF15932.5 EST46743.1 - 0.35 10.7 1.8 0.68 9.7 1.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) EGF_MSP1_1 PF12946.7 EST46743.1 - 1.2 9.3 6.3 7.6 6.7 0.2 2.8 2 1 0 2 2 2 0 MSP1 EGF domain 1 cEGF PF12662.7 EST46743.1 - 8.4 6.4 12.7 0.16 11.9 1.4 2.6 2 1 1 3 3 3 0 Complement Clr-like EGF-like Furin-like_2 PF15913.5 EST46744.1 - 0.013 15.7 2.6 0.013 15.7 2.6 3.5 1 1 2 3 3 3 0 Furin-like repeat, cysteine-rich VSP PF03302.13 EST46746.1 - 2.5e-09 36.5 37.1 2.5e-09 36.5 37.1 3.3 1 1 2 3 3 3 2 Giardia variant-specific surface protein Neogenin_C PF06583.12 EST46746.1 - 0.036 13.9 5.0 0.059 13.2 5.0 1.3 1 0 0 1 1 1 0 Neogenin C-terminus Furin-like_2 PF15913.5 EST46746.1 - 6.8 6.9 71.9 0.13 12.4 20.1 4.5 1 1 3 5 5 5 0 Furin-like repeat, cysteine-rich VSP PF03302.13 EST46747.1 - 3.9e-06 26.0 36.2 3.9e-06 26.0 36.2 2.3 1 1 1 2 2 2 1 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST46751.1 - 0.0034 17.5 27.0 0.0034 17.5 27.0 5.5 2 1 3 6 6 6 2 Furin-like repeat, cysteine-rich Dynein_light PF01221.18 EST46751.1 - 0.16 12.3 2.8 0.34 11.2 1.0 2.3 2 0 0 2 2 2 0 Dynein light chain type 1 DUF2254 PF10011.9 EST46754.1 - 0.2 10.5 0.0 0.29 9.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) DUF1375 PF07119.12 EST46756.1 - 0.072 13.5 0.1 0.19 12.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1375) zf-rbx1 PF12678.7 EST46758.1 - 3.5e-07 30.4 4.0 3.5e-07 30.4 4.0 2.1 3 0 0 3 3 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EST46758.1 - 4.4e-06 26.9 4.9 4.4e-06 26.9 4.9 2.9 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 EST46758.1 - 1.3e-05 25.1 7.7 6.4e-05 22.9 7.7 2.2 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 EST46758.1 - 2.4e-05 24.0 3.1 2.4e-05 24.0 3.1 2.9 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EST46758.1 - 0.0014 18.4 4.9 0.0014 18.4 4.9 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EST46758.1 - 0.0035 17.3 1.5 0.0035 17.3 1.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EST46758.1 - 0.014 15.2 7.3 0.059 13.3 7.1 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EST46758.1 - 0.033 14.2 1.2 0.11 12.5 1.2 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EST46758.1 - 0.045 13.4 1.8 0.13 11.9 1.8 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 EST46758.1 - 0.2 11.5 8.4 0.25 11.2 3.3 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EST46758.1 - 0.62 10.0 6.2 0.17 11.8 1.7 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TMEM70 PF06979.12 EST46758.1 - 3.1 8.2 6.5 0.98 9.8 0.2 2.7 3 0 0 3 3 3 0 Assembly, mitochondrial proton-transport ATP synth complex zf-C3HC4_4 PF15227.6 EST46758.1 - 3.1 8.0 7.0 13 6.1 1.6 2.6 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING SCAPER_N PF16501.5 EST46759.1 - 0.0075 16.3 0.8 0.013 15.5 0.8 1.5 1 1 0 1 1 1 1 S phase cyclin A-associated protein in the endoplasmic reticulum Bombinin PF05298.11 EST46759.1 - 0.062 13.0 0.0 0.08 12.6 0.0 1.1 1 0 0 1 1 1 0 Bombinin Reprolysin_3 PF13582.6 EST46759.1 - 0.13 12.8 0.2 0.17 12.4 0.2 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like GvpG PF05120.12 EST46760.1 - 4.2 7.5 24.5 1.1 9.3 5.7 3.7 3 1 0 3 3 3 0 Gas vesicle protein G AAA_12 PF13087.6 EST46761.1 - 1.3e-49 168.6 3.8 1.3e-49 168.6 3.8 1.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EST46761.1 - 2.6e-28 99.5 1.9 2.5e-27 96.3 1.9 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EST46761.1 - 3.5e-09 36.7 0.1 7.2e-08 32.4 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EST46761.1 - 1e-08 35.6 1.5 3.8e-06 27.3 0.1 3.6 3 2 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 EST46761.1 - 2e-06 27.7 0.6 0.00037 20.3 0.6 2.8 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 EST46761.1 - 0.0041 17.1 0.7 0.0041 17.1 0.7 3.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 EST46761.1 - 0.0062 16.0 0.4 0.1 12.1 0.4 2.5 1 1 0 1 1 1 1 PhoH-like protein Helicase_RecD PF05127.14 EST46761.1 - 0.12 12.2 1.4 3.4 7.5 0.2 3.1 2 1 0 2 2 2 0 Helicase UvrD_C_2 PF13538.6 EST46761.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Palm_thioest PF02089.15 EST46762.1 - 7.3e-58 196.3 0.1 8.4e-58 196.1 0.1 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 EST46762.1 - 0.0008 18.8 0.1 0.0049 16.2 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) LIDHydrolase PF10230.9 EST46762.1 - 0.0091 15.6 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Lipase_2 PF01674.18 EST46762.1 - 0.022 14.3 0.3 0.14 11.6 0.0 2.1 2 1 0 2 2 2 0 Lipase (class 2) Bap31 PF05529.12 EST46763.1 - 0.013 15.4 0.4 0.022 14.6 0.3 1.4 1 1 0 1 1 1 0 Bap31/Bap29 transmembrane region DUF4286 PF14114.6 EST46763.1 - 0.046 14.2 0.2 0.066 13.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4286) US22 PF02393.16 EST46764.1 - 0.012 15.8 0.0 0.02 15.2 0.0 1.3 1 0 0 1 1 1 0 US22 like WASH_WAHD PF11945.8 EST46766.1 - 0.091 12.3 2.9 0.41 10.1 2.9 1.9 1 1 0 1 1 1 0 WAHD domain of WASH complex Myb_DNA-binding PF00249.31 EST46772.1 - 4.4e-08 33.2 1.7 5.8e-08 32.8 1.7 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EST46772.1 - 1.1e-05 25.5 0.7 1.8e-05 24.8 0.7 1.2 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_6 PF13921.6 EST46772.1 - 1.2e-05 25.5 0.5 1.4e-05 25.3 0.5 1.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF1799 PF08809.11 EST46773.1 - 0.23 11.7 2.1 3.8 7.7 0.7 2.9 2 0 0 2 2 2 0 Phage related hypothetical protein (DUF1799) FliD_N PF02465.18 EST46773.1 - 3.1 8.5 15.2 0.71 10.6 8.0 3.4 2 2 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Abhydrolase_1 PF00561.20 EST46774.1 - 7.4e-11 42.2 0.0 1.4e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EST46774.1 - 1.2e-10 42.4 0.0 1.4e-10 42.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EST46774.1 - 3.9e-10 39.4 0.0 6e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 EST46774.1 - 6.1e-05 22.9 0.1 0.00041 20.2 0.0 2.1 1 1 1 2 2 2 1 Lipase (class 3) PGAP1 PF07819.13 EST46774.1 - 0.0019 18.0 0.2 0.0035 17.1 0.1 1.4 1 1 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 EST46774.1 - 0.0038 17.4 0.0 0.0059 16.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain DUF1799 PF08809.11 EST46775.1 - 0.23 11.7 2.1 3.8 7.7 0.7 2.9 2 0 0 2 2 2 0 Phage related hypothetical protein (DUF1799) FliD_N PF02465.18 EST46775.1 - 3.1 8.5 15.2 0.71 10.6 8.0 3.4 2 2 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Myb_DNA-binding PF00249.31 EST46776.1 - 4.4e-08 33.2 1.7 5.8e-08 32.8 1.7 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EST46776.1 - 1.1e-05 25.5 0.7 1.8e-05 24.8 0.7 1.2 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_6 PF13921.6 EST46776.1 - 1.2e-05 25.5 0.5 1.4e-05 25.3 0.5 1.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Rad52_Rad22 PF04098.15 EST46780.1 - 1.9e-31 109.0 0.0 2.7e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein ING PF12998.7 EST46782.1 - 0.63 10.7 5.7 1.3 9.7 2.9 2.1 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding GP24_25 PF17388.2 EST46783.1 - 0.0055 16.7 0.6 0.042 13.8 0.3 2.0 1 1 1 2 2 2 1 Tail assembly gene products 24 & 25 EFhand_Ca_insen PF08726.10 EST46783.1 - 0.022 14.8 1.0 0.28 11.3 0.0 2.7 1 1 2 3 3 3 0 Ca2+ insensitive EF hand CCDC32 PF14989.6 EST46783.1 - 0.05 13.6 4.3 0.091 12.8 4.3 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing 32 LMBR1 PF04791.16 EST46783.1 - 0.52 9.2 3.5 0.7 8.7 3.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Neur_chan_memb PF02932.16 EST46783.1 - 0.65 10.0 2.6 0.95 9.5 2.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF16 PF01519.16 EST46783.1 - 0.83 10.2 6.2 1.1 9.7 2.0 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 Aa_trans PF01490.18 EST46784.1 - 1.3e-09 37.3 37.7 6.1e-06 25.2 30.1 2.4 2 1 0 2 2 2 2 Transmembrane amino acid transporter protein DUF4407 PF14362.6 EST46784.1 - 0.04 13.3 0.1 0.087 12.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DPM3 PF08285.11 EST46784.1 - 0.13 12.5 0.3 0.13 12.5 0.3 3.2 4 1 0 4 4 4 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) SNF2_N PF00176.23 EST46786.1 - 5.2e-54 183.3 0.0 3.4e-53 180.6 0.0 2.1 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EST46786.1 - 5.8e-18 65.3 0.1 5.8e-18 65.3 0.1 3.5 5 0 0 5 5 5 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 EST46786.1 - 1.2e-15 57.4 1.9 4.9e-15 55.4 0.4 2.9 3 0 0 3 3 3 1 Bromodomain ResIII PF04851.15 EST46786.1 - 2.5e-07 30.9 0.0 2.5e-07 30.9 0.0 3.5 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_11 PF13086.6 EST46786.1 - 8.3 6.1 8.9 1.5 8.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain Collagen_mid PF15984.5 EST46788.1 - 0.085 12.6 0.5 0.19 11.5 0.5 1.5 1 0 0 1 1 1 0 Bacterial collagen, middle region DUF1505 PF07403.11 EST46793.1 - 0.062 13.5 0.3 0.11 12.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1505) zf-CHY PF05495.12 EST46797.1 - 1.8e-15 57.2 21.1 1.8e-15 57.2 21.1 3.1 2 1 0 2 2 2 1 CHY zinc finger zf-C3HC4_2 PF13923.6 EST46797.1 - 1.1e-07 31.6 7.9 1.1e-07 31.6 7.9 5.0 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EST46797.1 - 1.8e-06 28.1 9.3 1.8e-06 28.1 9.3 4.6 3 2 1 4 4 4 2 Ring finger domain zf-RING_UBOX PF13445.6 EST46797.1 - 3.5e-05 23.7 3.0 3.5e-05 23.7 3.0 4.7 5 1 1 6 6 6 1 RING-type zinc-finger zf-RING_5 PF14634.6 EST46797.1 - 0.002 18.1 5.3 0.002 18.1 5.3 5.5 3 2 1 4 4 4 1 zinc-RING finger domain YorP PF09629.10 EST46803.1 - 0.032 14.4 0.0 0.035 14.3 0.0 1.3 1 0 0 1 1 1 0 YorP protein Keratin_assoc PF09775.9 EST46803.1 - 0.1 12.3 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Keratinocyte-associated protein 2 ABC_tran PF00005.27 EST46804.1 - 4.3e-47 160.1 5.1 1.2e-26 93.8 0.0 3.5 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 EST46804.1 - 1.4e-15 57.9 0.9 0.00064 19.6 0.0 4.4 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EST46804.1 - 7.3e-07 28.8 0.1 0.012 15.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EST46804.1 - 5.7e-06 26.3 0.2 0.023 14.6 0.1 2.7 2 0 0 2 2 2 2 RsgA GTPase SMC_N PF02463.19 EST46804.1 - 0.00053 19.5 4.0 0.18 11.2 0.3 3.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EST46804.1 - 0.008 16.6 0.1 1.2 9.4 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 EST46804.1 - 0.012 16.1 10.1 0.033 14.7 0.0 3.4 4 0 0 4 4 4 0 AAA domain AAA_25 PF13481.6 EST46804.1 - 0.021 14.4 0.0 9.2 5.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EST46804.1 - 0.067 13.3 4.1 3.4 7.7 0.0 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_30 PF13604.6 EST46804.1 - 0.16 11.7 0.0 9 6.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EST46804.1 - 0.48 10.5 2.4 31 4.7 0.0 3.4 3 0 0 3 3 3 0 50S ribosome-binding GTPase GILT PF03227.16 EST46806.1 - 6.6e-05 23.1 0.0 0.00022 21.5 0.0 2.0 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) LRR_4 PF12799.7 EST46806.1 - 0.0052 17.2 5.3 0.39 11.2 0.2 4.5 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EST46806.1 - 0.016 15.0 8.3 0.031 14.0 0.3 4.5 5 0 0 5 5 5 0 Leucine rich repeat LRR_1 PF00560.33 EST46806.1 - 0.15 12.7 6.4 17 6.4 0.1 5.5 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 EST46806.1 - 0.58 10.4 3.7 61 4.0 0.0 4.7 4 0 0 4 4 4 0 Leucine Rich repeat CENP-W PF15510.6 EST46807.1 - 0.12 12.6 0.1 0.29 11.4 0.1 1.5 1 0 0 1 1 1 0 CENP-W protein VSP PF03302.13 EST46808.1 - 0.00017 20.6 48.4 0.00017 20.6 48.4 3.1 1 1 1 2 2 2 2 Giardia variant-specific surface protein DUF4690 PF15756.5 EST46808.1 - 0.04 14.5 0.2 0.65 10.6 0.0 2.5 2 0 0 2 2 2 0 Small Novel Rich in Cartilage DUF4748 PF15932.5 EST46808.1 - 0.16 11.8 0.1 0.41 10.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) tRNA-synt_1e PF01406.19 EST46811.1 - 0.17 11.2 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain GST_C PF00043.25 EST46814.1 - 0.012 15.9 0.4 0.067 13.4 0.1 2.2 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain ComFB PF10719.9 EST46814.1 - 0.019 15.0 0.0 0.039 14.0 0.0 1.5 1 0 0 1 1 1 0 Late competence development protein ComFB SAT PF16073.5 EST46814.1 - 0.038 13.7 0.1 0.072 12.8 0.1 1.4 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Orf78 PF06024.12 EST46815.1 - 0.87 9.9 9.7 13 6.1 4.1 2.9 2 0 0 2 2 2 0 Orf78 (ac78) EphA2_TM PF14575.6 EST46815.1 - 3.1 8.7 4.5 15 6.5 1.5 3.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TBPIP PF07106.13 EST46818.1 - 3.5e-13 49.3 0.3 1e-12 47.8 0.3 1.8 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain GIT_CC PF16559.5 EST46818.1 - 0.011 15.6 6.7 0.034 14.0 1.5 3.1 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor LZ3wCH PF18517.1 EST46818.1 - 0.014 15.5 0.1 0.041 14.0 0.1 1.9 1 0 0 1 1 1 0 Leucine zipper with capping helix domain YycI PF09648.10 EST46818.1 - 0.053 13.1 7.2 0.76 9.3 1.1 2.1 2 0 0 2 2 2 0 YycH protein ZapB PF06005.12 EST46818.1 - 0.08 13.4 13.1 0.43 11.1 13.1 2.4 1 1 0 1 1 1 0 Cell division protein ZapB bZIP_1 PF00170.21 EST46818.1 - 0.089 12.9 0.1 0.089 12.9 0.1 2.5 3 1 1 4 4 4 0 bZIP transcription factor CwsA PF10814.8 EST46818.1 - 0.54 10.4 2.5 0.53 10.5 1.4 1.6 2 0 0 2 2 2 0 Cell wall synthesis protein CwsA DivIC PF04977.15 EST46818.1 - 0.92 9.3 9.2 9.8 6.0 9.2 2.6 1 1 0 1 1 1 0 Septum formation initiator Fungal_TACC PF12709.7 EST46818.1 - 1 9.9 8.6 1.2 9.6 0.7 3.3 2 1 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins Adaptin_N PF01602.20 EST46819.1 - 3.6e-17 62.1 16.0 3.6e-17 62.1 16.0 2.7 1 1 1 2 2 2 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 EST46819.1 - 7.7e-13 48.5 3.8 2.6e-12 46.9 3.8 1.9 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT PF02985.22 EST46819.1 - 0.011 15.9 0.1 1.1 9.7 0.0 3.2 2 0 0 2 2 2 0 HEAT repeat Coatomer_b_Cpla PF14806.6 EST46819.1 - 0.02 14.9 0.2 0.077 13.0 0.2 2.1 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform HEAT_EZ PF13513.6 EST46819.1 - 0.02 15.4 0.0 0.075 13.6 0.0 2.0 1 0 0 1 1 1 0 HEAT-like repeat HEAT_2 PF13646.6 EST46819.1 - 0.029 14.7 0.0 0.33 11.4 0.0 2.4 1 1 2 3 3 3 0 HEAT repeats DUF4476 PF14771.6 EST46819.1 - 0.1 12.9 4.4 0.15 12.4 0.2 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4476) DUF5069 PF16798.5 EST46819.1 - 0.29 11.3 1.4 0.54 10.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5069) Pox_A22 PF04848.13 EST46820.1 - 0.00078 19.6 0.5 0.00086 19.4 0.5 1.1 1 0 0 1 1 1 1 Poxvirus A22 protein DUF378 PF04070.12 EST46822.1 - 0.0064 16.4 1.6 0.01 15.7 1.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF378) DUF981 PF06168.11 EST46822.1 - 0.034 14.1 0.2 0.044 13.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF981) FtsX_ECD PF18075.1 EST46823.1 - 0.018 15.6 1.7 2.7 8.7 0.5 3.1 2 1 1 3 3 3 0 FtsX extracellular domain GP68 PF17469.2 EST46823.1 - 0.15 12.5 0.2 24 5.4 0.0 2.6 2 0 0 2 2 2 0 Phage protein Gp68 MLANA PF14991.6 EST46824.1 - 0.093 13.0 0.4 0.14 12.4 0.4 1.4 1 0 0 1 1 1 0 Protein melan-A SP_C-Propep PF08999.10 EST46824.1 - 0.14 11.9 1.1 0.19 11.5 1.1 1.2 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide DUF5585 PF17823.1 EST46824.1 - 0.33 9.9 0.4 0.38 9.7 0.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5585) Glyco_hydro_18 PF00704.28 EST46825.1 - 0.056 13.2 0.4 0.075 12.7 0.4 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 18 Kinesin PF00225.23 EST46827.1 - 1.8e-08 33.7 0.1 2.9e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 Kinesin motor domain bZIP_2 PF07716.15 EST46827.1 - 0.027 14.6 1.2 0.99 9.5 1.0 2.5 3 0 0 3 3 3 0 Basic region leucine zipper Kinesin_assoc PF16183.5 EST46827.1 - 0.032 14.4 0.0 0.046 13.9 0.0 1.3 1 0 0 1 1 1 0 Kinesin-associated DivIC PF04977.15 EST46827.1 - 0.042 13.6 0.4 0.093 12.5 0.4 1.6 1 0 0 1 1 1 0 Septum formation initiator ABC_membrane_3 PF13748.6 EST46828.1 - 0.0083 15.4 6.1 0.57 9.4 0.1 2.4 1 1 1 2 2 2 2 ABC transporter transmembrane region YpsA PF06908.11 EST46828.1 - 0.039 13.9 1.4 0.063 13.3 0.6 1.7 2 0 0 2 2 2 0 YspA SLOG family GST_C PF00043.25 EST46829.1 - 0.0025 18.0 0.4 0.019 15.2 0.1 2.3 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain ComFB PF10719.9 EST46829.1 - 0.0068 16.5 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 Late competence development protein ComFB SAT PF16073.5 EST46829.1 - 0.017 14.8 0.1 0.025 14.3 0.1 1.2 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis GST_C_2 PF13410.6 EST46829.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ABC_tran_CTD PF16326.5 EST46843.1 - 0.026 14.8 1.2 0.064 13.5 0.3 1.9 2 0 0 2 2 2 0 ABC transporter C-terminal domain Occludin_ELL PF07303.13 EST46844.1 - 0.62 10.8 13.6 0.41 11.4 7.9 3.2 2 2 0 2 2 2 0 Occludin homology domain zinc-ribbon_6 PF10005.9 EST46844.1 - 1.2 9.9 6.5 1.2 9.8 1.1 2.3 1 1 1 2 2 2 0 zinc-ribbon domain Helicase_IV_N PF12462.8 EST46844.1 - 6.8 6.6 11.3 0.9 9.5 3.6 2.6 1 1 2 3 3 3 0 DNA helicase IV / RNA helicase N terminal SPATA1_C PF15743.5 EST46844.1 - 9.1 6.3 13.2 20 5.2 7.3 3.1 2 1 1 3 3 3 0 Spermatogenesis-associated C-terminus ORC2 PF04084.14 EST46846.1 - 0.017 14.0 0.0 0.018 14.0 0.0 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 2 zf-RING_2 PF13639.6 EST46847.1 - 1.4e-05 25.3 11.6 1.4e-05 25.3 11.6 1.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EST46847.1 - 0.00011 22.0 8.2 0.00011 22.0 8.2 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EST46847.1 - 0.00013 21.5 11.1 0.0002 20.9 11.1 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 EST46847.1 - 0.00044 19.9 9.2 0.0011 18.7 9.2 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EST46847.1 - 0.00091 19.2 5.9 0.0017 18.4 5.7 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EST46847.1 - 0.0026 17.6 8.5 0.0026 17.6 8.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EST46847.1 - 0.0058 16.8 7.1 0.012 15.7 7.1 1.6 1 1 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 EST46847.1 - 0.014 15.7 10.7 0.056 13.7 10.7 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain Zf_RING PF16744.5 EST46847.1 - 0.022 14.8 4.3 0.031 14.4 4.3 1.2 1 0 0 1 1 1 0 KIAA1045 RING finger zf-ANAPC11 PF12861.7 EST46847.1 - 0.21 11.6 7.2 0.5 10.4 7.2 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger EF-hand_1 PF00036.32 EST46848.1 - 2.5e-32 108.0 15.9 5.7e-09 34.9 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EST46848.1 - 1.4e-26 90.1 9.4 2.8e-08 33.0 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 EST46848.1 - 1.8e-26 92.4 12.1 3.6e-13 49.8 1.6 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EST46848.1 - 4.4e-20 71.3 10.6 1.2e-10 41.1 1.3 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 EST46848.1 - 4.7e-14 52.4 0.3 4.8e-06 26.8 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EST46848.1 - 9.4e-13 47.0 17.6 3.6e-05 23.1 0.1 4.9 4 1 1 5 5 5 4 EF hand EF-hand_4 PF12763.7 EST46848.1 - 7.8e-06 25.8 5.2 0.004 17.1 0.2 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SurA_N_3 PF13624.6 EST46848.1 - 0.00029 20.7 2.5 0.046 13.5 0.1 2.1 1 1 1 2 2 2 2 SurA N-terminal domain SurA_N_2 PF13623.6 EST46848.1 - 0.00035 20.5 1.4 0.58 10.0 0.1 2.4 2 1 0 2 2 2 2 SurA N-terminal domain EF-hand_14 PF17959.1 EST46848.1 - 0.003 17.9 2.6 0.91 9.9 0.2 2.5 2 1 0 2 2 2 2 EF-hand domain SUB1_ProdP9 PF18213.1 EST46848.1 - 0.0094 15.8 0.5 0.018 14.8 0.5 1.6 1 0 0 1 1 1 1 SUB1 protease Prodomain ProdP9 Caleosin PF05042.13 EST46848.1 - 0.012 15.6 5.1 2.5 8.0 0.0 3.7 1 1 3 4 4 4 0 Caleosin related protein MgtE_N PF03448.17 EST46848.1 - 0.19 12.4 3.3 0.93 10.1 0.5 2.7 1 1 0 2 2 2 0 MgtE intracellular N domain EF-hand_11 PF08976.11 EST46848.1 - 0.2 12.5 1.2 6.7 7.6 0.1 2.2 1 1 1 2 2 2 0 EF-hand domain NPV_P10 PF05531.12 EST46850.1 - 0.006 17.0 3.5 2.6 8.6 0.4 2.9 2 0 0 2 2 2 2 Nucleopolyhedrovirus P10 protein ATP-cone PF03477.16 EST46850.1 - 0.014 16.0 4.5 0.016 15.7 2.3 2.3 2 0 0 2 2 2 0 ATP cone domain Med9 PF07544.13 EST46850.1 - 0.088 12.9 4.7 0.07 13.2 1.7 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 TipAS PF07739.13 EST46850.1 - 0.11 13.1 1.1 0.2 12.2 1.1 1.5 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain zf-ZPR1 PF03367.13 EST46850.1 - 0.13 12.1 3.7 0.11 12.3 2.1 1.7 2 0 0 2 2 2 0 ZPR1 zinc-finger domain BST2 PF16716.5 EST46850.1 - 0.14 12.8 3.7 0.094 13.3 1.0 2.0 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 GvpK PF05121.12 EST46850.1 - 0.18 11.9 1.1 0.33 11.0 0.2 1.9 2 0 0 2 2 2 0 Gas vesicle protein K TPD52 PF04201.15 EST46850.1 - 0.38 10.3 5.4 4.4 6.9 2.3 2.5 1 1 1 2 2 2 0 Tumour protein D52 family DUF465 PF04325.13 EST46850.1 - 1.1 9.3 6.4 0.58 10.2 3.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF465) TolA_bind_tri PF16331.5 EST46850.1 - 1.2 9.3 8.0 6.4 6.9 3.5 2.6 2 0 0 2 2 2 0 TolA binding protein trimerisation Ribosomal_S27 PF01599.19 EST46851.1 - 1.6e-12 47.3 4.9 1.7e-12 47.3 4.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S27a NOB1_Zn_bind PF08772.11 EST46851.1 - 9.3e-05 22.5 0.9 0.0001 22.4 0.9 1.0 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like DZR PF12773.7 EST46851.1 - 0.0034 17.4 2.9 0.0065 16.5 2.9 1.5 1 1 0 1 1 1 1 Double zinc ribbon HypA PF01155.19 EST46851.1 - 0.016 15.3 1.5 0.016 15.3 1.5 1.0 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RNHCP PF12647.7 EST46851.1 - 0.031 14.3 2.6 0.036 14.0 2.6 1.1 1 0 0 1 1 1 0 RNHCP domain Nudix_N_2 PF14803.6 EST46851.1 - 0.033 14.1 6.2 0.13 12.2 6.2 1.8 1 1 0 1 1 1 0 Nudix N-terminal DUF1451 PF07295.11 EST46851.1 - 0.076 13.0 1.0 0.071 13.1 1.0 1.0 1 0 0 1 1 1 0 Zinc-ribbon containing domain zinc_ribbon_2 PF13240.6 EST46851.1 - 0.095 12.4 7.2 1.4 8.8 7.2 2.1 1 1 0 1 1 1 0 zinc-ribbon domain A2L_zn_ribbon PF08792.10 EST46851.1 - 0.16 11.7 6.1 1.9 8.3 2.3 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain Zn-ribbon_8 PF09723.10 EST46851.1 - 0.19 11.9 3.7 0.98 9.6 3.7 1.8 1 1 1 2 2 2 0 Zinc ribbon domain zf-RRN7 PF11781.8 EST46851.1 - 0.29 10.9 6.2 4.5 7.0 0.3 2.1 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Toprim_4 PF13662.6 EST46852.1 - 0.016 15.6 0.0 0.04 14.4 0.0 1.6 2 0 0 2 2 2 0 Toprim domain Peptidase_C1 PF00112.23 EST46853.1 - 1.5e-57 195.2 9.4 1.8e-57 195.0 9.4 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EST46853.1 - 1.8e-08 33.6 2.4 0.00092 18.1 0.2 2.2 2 0 0 2 2 2 2 Peptidase C1-like family HRM PF02793.22 EST46853.1 - 0.12 12.7 3.3 10 6.5 0.1 2.4 2 0 0 2 2 2 0 Hormone receptor domain IlvC PF01450.19 EST46854.1 - 0.018 15.3 0.5 0.024 14.9 0.5 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Acetyltransf_5 PF13444.6 EST46854.1 - 0.077 13.7 0.3 2.6 8.8 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Clathrin PF00637.20 EST46855.1 - 2.5e-06 27.4 7.9 0.49 10.3 0.0 5.2 3 2 2 5 5 5 5 Region in Clathrin and VPS Ago_N_1 PF18351.1 EST46855.1 - 0.17 12.3 1.0 0.75 10.3 0.3 2.4 2 0 0 2 2 2 0 Fungal Argonaute N-terminal domain VSP PF03302.13 EST46857.1 - 6 5.6 75.3 1.9 7.3 15.9 3.4 1 1 2 3 3 3 0 Giardia variant-specific surface protein RELT PF12606.8 EST46859.1 - 0.074 12.0 0.1 0.15 11.1 0.1 1.5 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 AAA PF00004.29 EST46864.1 - 1.9e-14 54.2 0.0 6.1e-14 52.6 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EST46864.1 - 6.5e-11 42.3 0.0 1.2e-09 38.2 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 EST46864.1 - 3e-06 27.5 0.0 6.5e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EST46864.1 - 3.5e-05 24.3 0.1 9.6e-05 22.8 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EST46864.1 - 6.3e-05 22.8 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 EST46864.1 - 7.2e-05 22.6 0.0 0.00011 22.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EST46864.1 - 0.00011 22.3 0.0 0.0019 18.2 0.0 2.1 1 1 1 2 2 2 1 AAA domain Rad17 PF03215.15 EST46864.1 - 0.00014 21.9 0.0 0.00026 21.0 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_5 PF07728.14 EST46864.1 - 0.00044 20.3 0.0 0.0013 18.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 EST46864.1 - 0.00047 19.9 0.2 0.0014 18.4 0.2 1.8 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EST46864.1 - 0.00088 18.7 0.0 0.0085 15.5 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EST46864.1 - 0.001 19.6 0.0 0.0015 19.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EST46864.1 - 0.0015 18.4 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 EST46864.1 - 0.0016 18.6 0.0 0.0027 17.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_28 PF13521.6 EST46864.1 - 0.0026 18.0 0.0 0.0044 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EST46864.1 - 0.0031 17.0 0.0 0.0049 16.4 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_3 PF07726.11 EST46864.1 - 0.0036 17.2 0.0 0.0076 16.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 EST46864.1 - 0.0039 16.4 0.0 0.0058 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.6 EST46864.1 - 0.0064 16.8 0.2 0.053 13.9 0.1 2.3 2 1 0 2 2 1 1 AAA domain AAA_23 PF13476.6 EST46864.1 - 0.0095 16.5 0.0 0.013 16.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EST46864.1 - 0.0098 15.0 0.0 0.12 11.5 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_33 PF13671.6 EST46864.1 - 0.014 15.6 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EST46864.1 - 0.018 15.4 0.0 0.049 14.0 0.0 1.7 2 0 0 2 2 1 0 RNA helicase NTPase_1 PF03266.15 EST46864.1 - 0.029 14.3 0.0 0.37 10.7 0.0 2.1 2 0 0 2 2 2 0 NTPase SRP54 PF00448.22 EST46864.1 - 0.039 13.6 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_29 PF13555.6 EST46864.1 - 0.042 13.6 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 EST46864.1 - 0.086 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family TniB PF05621.11 EST46864.1 - 0.09 12.2 0.0 0.48 9.8 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein DEAD PF00270.29 EST46864.1 - 0.13 12.1 0.1 0.53 10.0 0.0 1.9 1 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_27 PF13514.6 EST46864.1 - 0.15 11.6 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_6 PF12774.7 EST46864.1 - 0.17 10.8 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Rep_fac_C PF08542.11 EST46864.1 - 0.17 12.3 0.0 0.39 11.1 0.0 1.6 1 0 0 1 1 1 0 Replication factor C C-terminal domain AAA_assoc_2 PF16193.5 EST46864.1 - 0.18 12.2 1.1 0.73 10.2 0.0 2.4 3 0 0 3 3 2 0 AAA C-terminal domain PEPCK_ATP PF01293.20 EST46864.1 - 0.23 10.1 0.0 0.35 9.5 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase IF-2B PF01008.17 EST46865.1 - 2.1e-14 53.4 0.0 2.5e-13 49.9 0.0 2.3 1 1 0 1 1 1 1 Initiation factor 2 subunit family Pyr_redox_2 PF07992.14 EST46867.1 - 0.017 14.4 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 EST46867.1 - 0.053 13.8 0.1 0.23 11.7 0.1 2.0 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Thoc2 PF11732.8 EST46867.1 - 0.079 13.0 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Transcription- and export-related complex subunit Histone PF00125.24 EST46868.1 - 9.2e-13 48.7 0.4 9.2e-13 48.7 0.4 1.3 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EST46868.1 - 0.008 16.4 0.4 0.014 15.7 0.4 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 EST46868.1 - 0.092 12.9 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Vel1p PF10339.9 EST46868.1 - 0.15 11.4 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Yeast-specific zinc responsive ATP_bind_3 PF01171.20 EST46869.1 - 6.6e-13 48.8 0.0 1.6e-12 47.5 0.0 1.6 2 0 0 2 2 2 1 PP-loop family ATP-synt_ab PF00006.25 EST46870.1 - 7.3e-56 189.2 0.1 2.8e-41 141.5 0.0 2.1 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EST46870.1 - 6.2e-09 36.3 0.4 1.3e-08 35.2 0.4 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 EST46870.1 - 0.0011 19.1 0.3 0.0028 17.8 0.3 1.7 1 0 0 1 1 1 1 HAS barrel domain ArfGap PF01412.18 EST46871.1 - 0.0002 21.4 1.5 0.0002 21.4 1.5 2.6 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf DUF4871 PF16167.5 EST46871.1 - 0.043 13.8 0.5 0.12 12.3 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4871) MoaF_C PF17409.2 EST46871.1 - 0.11 12.2 0.2 0.41 10.3 0.1 2.0 2 0 0 2 2 2 0 MoaF C-terminal domain Epsilon_antitox PF08998.11 EST46872.1 - 0.058 13.7 0.1 0.18 12.1 0.1 1.8 1 0 0 1 1 1 0 Bacterial epsilon antitoxin Pkinase PF00069.25 EST46874.1 - 5.3e-54 183.3 1.5 7.7e-54 182.8 1.5 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST46874.1 - 1.1e-41 142.9 0.4 1.4e-41 142.5 0.4 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EST46874.1 - 0.002 17.5 0.1 0.0036 16.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EST46874.1 - 0.075 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Metallophos PF00149.28 EST46875.1 - 1e-31 111.1 0.1 1.5e-31 110.5 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase T2SSE_N PF05157.15 EST46876.1 - 0.055 13.7 0.1 0.14 12.4 0.1 1.8 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein E, N-terminal domain YfbU PF03887.14 EST46876.1 - 0.14 12.2 0.2 0.21 11.6 0.2 1.5 1 1 0 1 1 1 0 YfbU domain ECF_trnsprt PF12822.7 EST46877.1 - 0.075 13.1 0.0 2.8 8.0 0.0 2.0 1 1 1 2 2 2 0 ECF transporter, substrate-specific component BLOC1_2 PF10046.9 EST46878.1 - 0.0069 16.7 7.7 0.0069 16.7 7.7 4.5 2 2 2 4 4 4 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATG16 PF08614.11 EST46878.1 - 0.076 13.2 37.3 0.019 15.2 6.6 2.8 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Jnk-SapK_ap_N PF09744.9 EST46878.1 - 0.13 12.4 41.7 0.81 9.9 13.8 3.2 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 Golgin_A5 PF09787.9 EST46878.1 - 0.57 9.6 40.9 1.4 8.3 22.8 2.6 1 1 1 2 2 2 0 Golgin subfamily A member 5 LURAP PF14854.6 EST46878.1 - 0.61 10.0 15.6 1 9.3 0.3 3.6 3 1 1 4 4 4 0 Leucine rich adaptor protein HMMR_C PF15908.5 EST46878.1 - 0.83 9.9 30.8 0.8 10.0 4.4 4.2 2 2 2 4 4 4 0 Hyaluronan mediated motility receptor C-terminal JIP_LZII PF16471.5 EST46878.1 - 1.5 9.1 29.1 0.2 11.9 2.3 5.7 3 2 2 6 6 6 0 JNK-interacting protein leucine zipper II TPR_MLP1_2 PF07926.12 EST46878.1 - 2.7 8.1 44.0 0.056 13.5 1.6 4.5 2 2 1 3 3 3 0 TPR/MLP1/MLP2-like protein GAS PF13851.6 EST46878.1 - 3.2 7.0 43.5 0.21 10.9 12.4 3.0 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding ERM PF00769.19 EST46878.1 - 6.8 6.4 41.8 8.5 6.1 24.2 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family CLAMP PF14769.6 EST46883.1 - 7.5e-05 23.1 0.7 0.00014 22.2 0.7 1.5 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 P_C10 PF14974.6 EST46885.1 - 0.018 15.2 0.2 0.17 12.0 0.1 2.8 2 0 0 2 2 2 0 Protein C10 RT_RNaseH PF17917.1 EST46885.1 - 0.041 14.2 0.2 0.19 12.0 0.0 2.3 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase Ank_2 PF12796.7 EST46887.1 - 5.2e-06 26.9 0.2 1.4e-05 25.6 0.1 1.7 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EST46887.1 - 2.1e-05 25.0 0.1 0.00015 22.2 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) bZIP_1 PF00170.21 EST46887.1 - 0.00078 19.5 2.6 0.0022 18.1 2.6 1.8 1 0 0 1 1 1 1 bZIP transcription factor REPA_OB_2 PF16900.5 EST46887.1 - 0.015 15.2 0.3 0.046 13.6 0.3 1.8 1 0 0 1 1 1 0 Replication protein A OB domain Ank_5 PF13857.6 EST46887.1 - 0.017 15.5 0.0 0.85 10.0 0.0 2.5 1 1 1 2 2 2 0 Ankyrin repeats (many copies) JIP_LZII PF16471.5 EST46887.1 - 0.051 13.7 3.3 0.11 12.7 2.7 1.9 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II eRF1_3 PF03465.15 EST46887.1 - 0.062 13.8 0.9 0.11 13.0 0.9 1.4 1 0 0 1 1 1 0 eRF1 domain 3 NRBF2 PF08961.10 EST46887.1 - 0.21 11.2 9.1 0.21 11.2 5.6 2.3 2 1 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator YabA PF06156.13 EST46887.1 - 2.6 8.8 8.6 1.9 9.2 5.3 2.3 1 1 1 2 2 2 0 Initiation control protein YabA DivIC PF04977.15 EST46887.1 - 2.6 7.9 11.3 0.14 11.9 3.3 2.7 2 0 0 2 2 2 0 Septum formation initiator Ank_2 PF12796.7 EST46891.1 - 4.4e-30 104.1 9.7 1.2e-10 41.9 0.7 5.5 1 1 5 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EST46891.1 - 1.3e-15 57.5 0.9 0.018 15.6 0.2 7.1 5 2 2 8 8 8 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EST46891.1 - 2.8e-11 43.4 0.0 0.013 15.8 0.0 5.9 5 1 2 7 7 7 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EST46891.1 - 5.1e-10 38.7 0.2 0.13 12.8 0.0 8.1 9 0 0 9 9 9 1 Ankyrin repeat Ank PF00023.30 EST46891.1 - 7.6e-05 23.0 0.0 1.5 9.4 0.0 5.4 6 0 0 6 6 6 1 Ankyrin repeat DUF3447 PF11929.8 EST46891.1 - 0.015 15.3 15.7 0.18 11.8 0.6 4.5 3 2 2 5 5 5 0 Domain of unknown function (DUF3447) DUF4180 PF13788.6 EST46892.1 - 0.062 13.2 0.0 0.076 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4180) AAA PF00004.29 EST46894.1 - 1.6e-72 242.1 0.0 2.2e-40 138.2 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EST46894.1 - 9.4e-19 67.0 0.0 3.8e-10 39.4 0.0 2.5 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EST46894.1 - 1.9e-08 34.9 0.7 0.11 12.9 0.0 4.1 2 2 1 3 3 3 2 AAA ATPase domain RuvB_N PF05496.12 EST46894.1 - 2.2e-07 30.7 0.0 0.015 15.0 0.0 2.8 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 EST46894.1 - 8.2e-07 28.9 0.0 0.033 13.9 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 EST46894.1 - 1.2e-06 28.6 0.0 0.029 14.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EST46894.1 - 1.6e-06 28.5 0.0 0.034 14.5 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.6 EST46894.1 - 1.7e-06 28.6 0.0 0.058 13.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 EST46894.1 - 3.5e-06 27.0 0.6 0.11 12.4 0.1 3.6 2 1 0 2 2 2 1 NACHT domain TsaE PF02367.17 EST46894.1 - 4.9e-06 26.5 0.0 0.11 12.5 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 EST46894.1 - 1.1e-05 25.1 2.5 5.7 6.5 0.0 4.2 3 1 1 4 4 4 0 AAA domain AAA_22 PF13401.6 EST46894.1 - 1.7e-05 25.1 0.4 0.32 11.3 0.0 3.6 2 2 1 3 3 3 2 AAA domain AAA_28 PF13521.6 EST46894.1 - 2.2e-05 24.8 0.0 0.12 12.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 EST46894.1 - 4.9e-05 22.7 0.1 0.0097 15.1 0.0 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_2 PF07724.14 EST46894.1 - 0.00011 22.4 0.0 0.13 12.4 0.0 2.8 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EST46894.1 - 0.00018 21.5 0.0 0.89 9.6 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EST46894.1 - 0.00079 19.6 0.2 0.24 11.6 0.0 3.1 2 2 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EST46894.1 - 0.00089 18.7 0.6 1.1 8.6 0.0 2.7 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI ATPase PF06745.13 EST46894.1 - 0.00089 18.7 0.6 2.7 7.3 0.0 3.5 4 0 0 4 4 3 1 KaiC DUF815 PF05673.13 EST46894.1 - 0.0012 18.0 0.0 0.63 9.2 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 EST46894.1 - 0.003 18.1 0.8 2.7 8.5 0.0 2.8 3 0 0 3 3 2 1 ABC transporter ATPase_2 PF01637.18 EST46894.1 - 0.0039 17.1 0.0 0.17 11.8 0.0 2.9 2 2 1 3 3 3 1 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 EST46894.1 - 0.0039 16.5 0.1 0.23 10.7 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin Sigma54_activat PF00158.26 EST46894.1 - 0.0041 16.8 0.0 0.99 9.1 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain T2SSE PF00437.20 EST46894.1 - 0.009 15.1 0.0 0.034 13.2 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_7 PF12775.7 EST46894.1 - 0.011 15.2 0.0 3.1 7.3 0.0 2.8 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_3 PF07726.11 EST46894.1 - 0.012 15.5 0.0 1.3 8.9 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 EST46894.1 - 0.018 14.8 0.5 3.2 7.5 0.0 3.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DnaB_C PF03796.15 EST46894.1 - 0.019 14.3 0.5 11 5.3 0.0 3.1 2 1 1 3 3 3 0 DnaB-like helicase C terminal domain Bac_DnaA PF00308.18 EST46894.1 - 0.022 14.6 0.0 11 5.8 0.0 2.9 2 1 0 2 2 2 0 Bacterial dnaA protein AAA_24 PF13479.6 EST46894.1 - 0.041 13.6 0.4 11 5.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 EST46894.1 - 0.045 13.0 0.0 0.29 10.3 0.0 2.0 2 0 0 2 2 2 0 KAP family P-loop domain Rad17 PF03215.15 EST46894.1 - 0.058 13.3 0.0 1.3 8.9 0.0 2.6 3 0 0 3 3 3 0 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 EST46894.1 - 0.069 13.3 0.1 10 6.2 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.22 EST46894.1 - 0.073 12.2 0.0 3.4 6.8 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain DUF2075 PF09848.9 EST46894.1 - 0.1 11.8 0.1 2 7.6 0.0 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 EST46894.1 - 0.11 11.9 0.2 6.9 6.1 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein SKI PF01202.22 EST46894.1 - 0.11 12.6 0.0 1.3 9.2 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase AAA_29 PF13555.6 EST46894.1 - 0.12 12.1 0.1 2.9 7.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 EST46894.1 - 0.13 12.2 0.0 2.9 7.8 0.0 2.5 2 0 0 2 2 2 0 NTPase Adeno_IVa2 PF02456.15 EST46894.1 - 0.17 10.6 1.1 1.1 7.9 0.1 2.4 3 0 0 3 3 3 0 Adenovirus IVa2 protein ResIII PF04851.15 EST46894.1 - 0.17 11.8 0.0 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit WD40_like PF17005.5 EST46895.1 - 2.4e-05 23.8 4.4 0.003 16.9 0.0 3.2 1 1 2 3 3 3 2 WD40-like domain ANAPC4_WD40 PF12894.7 EST46895.1 - 0.00054 20.2 0.2 14 6.0 0.0 4.3 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EST46895.1 - 0.0084 16.1 0.0 0.17 11.9 0.0 2.6 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region DUF3874 PF12990.7 EST46895.1 - 0.098 13.0 0.4 0.26 11.6 0.4 1.7 1 0 0 1 1 1 0 Domain of unknonw function from B. Theta Gene description (DUF3874) EMP24_GP25L PF01105.24 EST46896.1 - 4.5e-15 56.0 0.1 5.9e-15 55.7 0.1 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Zein PF01559.16 EST46897.1 - 6.1 6.4 12.7 0.11 12.1 1.4 2.3 2 0 0 2 2 2 0 Zein seed storage protein TPR_2 PF07719.17 EST46898.1 - 8.8e-28 94.2 1.4 0.0026 17.8 0.0 11.9 12 0 0 12 12 12 5 Tetratricopeptide repeat TPR_1 PF00515.28 EST46898.1 - 2.4e-21 74.6 7.9 0.0048 16.7 0.0 11.1 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_19 PF14559.6 EST46898.1 - 2.5e-15 56.7 13.1 0.00058 20.3 0.0 7.7 6 2 3 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 EST46898.1 - 9.9e-15 53.5 7.7 0.11 12.8 0.0 10.6 11 1 1 12 12 11 2 Tetratricopeptide repeat TPR_16 PF13432.6 EST46898.1 - 6.5e-14 52.3 0.0 3.4e-06 27.6 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EST46898.1 - 4.8e-11 42.7 17.8 1e-05 25.7 0.1 6.1 6 2 1 7 7 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EST46898.1 - 2e-09 37.6 17.2 0.065 13.5 0.0 8.8 6 2 5 11 11 11 4 Tetratricopeptide repeat TPR_14 PF13428.6 EST46898.1 - 9.1e-08 32.3 8.2 2.2 9.3 0.0 8.3 6 3 4 10 10 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 EST46898.1 - 2e-07 30.6 1.7 8 6.7 0.0 7.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 EST46898.1 - 2.6e-07 30.8 21.9 0.13 13.0 0.0 8.3 11 0 0 11 11 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 EST46898.1 - 3.8e-06 26.5 8.5 0.17 11.6 0.1 5.7 7 0 0 7 7 7 2 TPR repeat TPR_15 PF13429.6 EST46898.1 - 0.0018 17.5 2.2 0.3 10.2 0.2 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 EST46898.1 - 0.002 17.8 0.0 0.002 17.8 0.0 4.1 4 2 1 5 5 5 1 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 EST46898.1 - 0.0048 17.0 3.5 5.2 7.3 0.0 4.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.6 EST46898.1 - 0.008 16.5 2.4 0.2 12.0 0.0 4.3 5 1 0 5 5 5 1 Tetratricopeptide repeat DUF4919 PF16266.5 EST46898.1 - 0.046 13.7 2.6 0.048 13.6 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4919) TPR_10 PF13374.6 EST46898.1 - 0.051 13.5 7.4 1.3 9.0 0.0 5.9 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 EST46898.1 - 0.099 13.1 2.9 31 5.3 0.0 6.2 9 1 0 9 9 6 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 EST46898.1 - 0.1 12.5 0.0 0.5 10.3 0.0 2.1 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal SHNi-TPR PF10516.9 EST46898.1 - 0.18 11.2 6.6 1.4 8.4 0.1 3.5 3 0 0 3 3 3 0 SHNi-TPR RPN7 PF10602.9 EST46898.1 - 0.49 10.1 5.0 4.6 6.9 0.0 3.7 4 0 0 4 4 4 0 26S proteasome subunit RPN7 SDH_alpha PF03313.15 EST46899.1 - 5.9e-59 199.9 4.5 1.2e-58 198.8 4.5 1.4 1 1 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 EST46899.1 - 5.9e-26 91.7 0.4 7.4e-15 55.6 0.2 2.4 1 1 1 2 2 2 2 Serine dehydratase beta chain Pep3_Vps18 PF05131.14 EST46900.1 - 0.0011 18.9 0.7 0.0011 18.9 0.7 2.3 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Vps39_2 PF10367.9 EST46900.1 - 0.028 14.8 1.3 0.028 14.8 1.3 2.9 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 zf-RING_5 PF14634.6 EST46900.1 - 0.56 10.2 13.3 1.5 8.8 13.3 1.8 1 0 0 1 1 1 0 zinc-RING finger domain TPR_19 PF14559.6 EST46900.1 - 0.61 10.6 2.5 21 5.7 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-RING_2 PF13639.6 EST46900.1 - 2.5 8.5 12.3 5.9 7.3 12.3 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_11 PF17123.5 EST46900.1 - 3.2 7.6 10.1 3.8 7.3 8.2 2.2 2 0 0 2 2 2 0 RING-like zinc finger Ank_2 PF12796.7 EST46901.1 - 4.1e-07 30.5 0.1 0.00036 21.0 0.0 3.4 2 1 2 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EST46901.1 - 0.00031 21.0 0.1 7.6 7.5 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 EST46901.1 - 0.00082 19.9 0.4 0.089 13.4 0.2 3.3 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EST46901.1 - 0.0027 18.0 0.0 3.1 8.2 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) EFhand_Ca_insen PF08726.10 EST46901.1 - 0.14 12.3 0.5 3.9 7.6 0.1 2.4 2 0 0 2 2 2 0 Ca2+ insensitive EF hand DUF3447 PF11929.8 EST46901.1 - 1.8 8.6 8.0 4.4 7.3 0.3 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF3447) TPR_1 PF00515.28 EST46902.1 - 3.4e-18 64.6 7.1 0.0035 17.1 0.0 7.8 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 EST46902.1 - 4.4e-12 45.1 27.4 0.0006 19.7 4.0 8.7 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_11 PF13414.6 EST46902.1 - 8e-10 38.2 12.5 0.0048 16.6 0.0 5.9 5 1 1 6 6 6 3 TPR repeat TPR_19 PF14559.6 EST46902.1 - 3.8e-09 36.9 25.4 0.091 13.3 0.4 6.7 4 2 2 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 EST46902.1 - 4.8e-09 36.0 2.8 0.032 14.6 0.0 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EST46902.1 - 8e-09 36.0 11.7 0.23 12.1 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 EST46902.1 - 6.1e-08 32.8 19.6 0.021 15.1 0.0 6.8 4 3 2 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 EST46902.1 - 1.1e-07 31.5 14.8 0.19 12.1 0.6 7.2 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 EST46902.1 - 2.4e-07 31.0 18.7 0.097 13.5 2.3 6.5 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 EST46902.1 - 3.5e-05 23.5 18.0 0.11 12.5 2.7 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EST46902.1 - 0.00019 21.6 13.9 1.1 9.5 0.3 5.1 4 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EST46902.1 - 0.00049 19.9 19.7 0.085 12.9 1.4 6.2 7 1 0 7 7 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 EST46902.1 - 0.00088 19.4 6.3 21 5.3 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Coatomer_E PF04733.14 EST46902.1 - 0.0056 16.1 0.3 0.25 10.7 0.0 2.4 2 0 0 2 2 2 1 Coatomer epsilon subunit TPR_6 PF13174.6 EST46902.1 - 0.012 16.1 17.6 6.6 7.6 0.8 6.5 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 EST46902.1 - 0.023 15.3 2.1 0.023 15.3 2.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat SNAP PF14938.6 EST46902.1 - 0.067 12.6 4.2 7.7 5.9 0.5 3.2 2 1 1 3 3 3 0 Soluble NSF attachment protein, SNAP Fis1_TPR_C PF14853.6 EST46902.1 - 0.12 12.4 11.6 1.7 8.8 0.8 4.8 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.6 EST46902.1 - 3.2 6.9 14.6 1.7 7.8 2.9 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat AAA_lid_2 PF17863.1 EST46903.1 - 0.0068 16.2 0.2 0.024 14.5 0.1 2.0 2 0 0 2 2 2 1 AAA lid domain TMEM131_like PF12371.8 EST46904.1 - 0.22 11.8 4.4 9.4 6.6 0.0 3.7 4 0 0 4 4 4 0 Transmembrane protein 131-like Fip1 PF05182.13 EST46905.1 - 1.8e-12 46.6 0.9 2.8e-12 46.0 0.9 1.3 1 0 0 1 1 1 1 Fip1 motif Glyco_transf_41 PF13844.6 EST46906.1 - 1.9e-36 125.5 7.8 4.2e-20 71.6 0.2 3.0 2 1 1 3 3 3 2 Glycosyl transferase family 41 TPR_1 PF00515.28 EST46906.1 - 9.5e-09 34.7 7.4 9.3e-05 22.1 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EST46906.1 - 5.4e-08 32.4 8.6 0.00098 19.1 0.1 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EST46906.1 - 9.4e-05 22.0 6.3 0.00062 19.4 0.0 3.4 3 0 0 3 3 3 1 TPR repeat TPR_7 PF13176.6 EST46906.1 - 0.0011 18.9 2.2 0.016 15.2 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EST46906.1 - 0.024 15.3 0.0 1.3 9.8 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EST46906.1 - 0.06 13.6 0.2 0.06 13.6 0.2 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 EST46906.1 - 0.15 12.3 5.6 0.68 10.3 0.2 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat RrnaAD PF00398.20 EST46907.1 - 4.4e-53 180.0 0.4 5.5e-53 179.7 0.4 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EST46907.1 - 1.2e-08 35.5 0.0 2.4e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EST46907.1 - 1.2e-05 25.2 0.0 2.3e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EST46907.1 - 2.7e-05 24.0 0.0 5.7e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EST46907.1 - 3.8e-05 24.2 0.0 8e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EST46907.1 - 4.2e-05 23.4 0.0 6.9e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DREV PF05219.12 EST46907.1 - 0.0008 18.6 0.0 0.0015 17.7 0.0 1.4 1 0 0 1 1 1 1 DREV methyltransferase NodS PF05401.11 EST46907.1 - 0.0011 18.6 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_12 PF08242.12 EST46907.1 - 0.0014 19.4 0.0 0.0028 18.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 EST46907.1 - 0.04 13.7 0.0 0.18 11.7 0.0 2.0 2 1 0 2 2 2 0 PRMT5 arginine-N-methyltransferase MTS PF05175.14 EST46907.1 - 0.043 13.4 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain ILVD_EDD PF00920.21 EST46907.1 - 0.092 11.3 0.0 0.4 9.3 0.0 1.8 2 0 0 2 2 2 0 Dehydratase family Methyltransf_2 PF00891.18 EST46907.1 - 0.098 11.9 0.0 0.63 9.3 0.0 2.0 2 0 0 2 2 2 0 O-methyltransferase domain WD40 PF00400.32 EST46909.1 - 0.00044 21.0 3.2 0.0019 19.0 0.2 3.7 4 1 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EST46909.1 - 0.00047 20.4 3.8 12 6.3 0.0 5.5 6 0 0 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain CLP1_N PF16573.5 EST46913.1 - 0.0061 16.8 1.0 0.19 12.0 0.2 2.7 2 0 0 2 2 2 2 N-terminal beta-sandwich domain of polyadenylation factor Methyltransf_23 PF13489.6 EST46914.1 - 2.1e-09 37.4 0.8 4.3e-09 36.4 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EST46914.1 - 1.5e-08 35.2 0.0 4.3e-08 33.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EST46914.1 - 0.00035 21.2 0.3 0.0035 18.0 0.1 2.8 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EST46914.1 - 0.0062 15.9 0.2 0.0062 15.9 0.2 2.2 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EST46914.1 - 0.0078 16.0 7.9 0.008 16.0 2.6 3.0 2 1 0 2 2 2 1 Methyltransferase domain KNTase_C PF07827.11 EST46914.1 - 0.044 13.6 0.1 0.099 12.5 0.1 1.5 1 0 0 1 1 1 0 KNTase C-terminal domain Methyltransf_12 PF08242.12 EST46914.1 - 0.078 13.7 3.4 0.26 12.1 0.4 3.2 2 1 0 2 2 2 0 Methyltransferase domain TPR_2 PF07719.17 EST46916.1 - 3.3e-08 33.0 10.8 0.37 11.0 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EST46916.1 - 5.9e-07 29.2 13.0 0.00034 20.6 0.1 6.6 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_1 PF00515.28 EST46916.1 - 5.1e-06 26.1 13.4 1.3 8.9 0.2 6.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 EST46916.1 - 0.0059 16.3 2.9 3.3 7.5 0.0 4.4 3 1 1 4 4 4 1 TPR repeat TPR_12 PF13424.6 EST46916.1 - 0.012 15.9 1.2 10 6.5 0.0 3.7 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EST46916.1 - 0.017 15.8 0.2 25 5.8 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Anillin_N PF16018.5 EST46916.1 - 0.035 14.7 1.2 0.081 13.5 1.2 1.6 1 0 0 1 1 1 0 Anillin N-terminus DRAT PF07357.11 EST46916.1 - 0.036 13.3 0.7 0.063 12.5 0.7 1.4 1 0 0 1 1 1 0 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) ANAPC3 PF12895.7 EST46916.1 - 4.8 7.5 7.4 2.1 8.6 0.1 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF4468 PF14730.6 EST46917.1 - 0.005 17.1 3.6 0.005 17.1 3.6 2.9 2 2 0 2 2 2 1 Domain of unknown function (DUF4468) with TBP-like fold FlaC_arch PF05377.11 EST46917.1 - 0.012 16.0 2.2 0.012 16.0 2.2 4.5 4 2 1 5 5 5 0 Flagella accessory protein C (FlaC) FAD-SLDH PF12318.8 EST46917.1 - 1 9.4 6.9 2.6 8.1 6.9 1.7 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase PRKG1_interact PF15898.5 EST46917.1 - 3.4 8.6 44.1 1.7 9.6 7.5 3.7 2 2 2 4 4 4 0 cGMP-dependent protein kinase interacting domain LRR_9 PF14580.6 EST46918.1 - 1.2e-12 47.6 8.6 3.3e-12 46.3 8.6 1.7 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 EST46918.1 - 1.9e-06 27.6 13.8 7.8e-05 22.4 2.3 3.5 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 EST46918.1 - 3.6e-06 27.2 23.9 0.0019 18.6 2.7 4.3 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) Pertactin PF03212.14 EST46919.1 - 0.081 12.9 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 Pertactin RNase_H PF00075.24 EST46920.1 - 1.6e-34 119.1 0.0 2.7e-24 86.0 0.0 2.4 2 0 0 2 2 2 2 RNase H DrrA_P4M PF14860.6 EST46920.1 - 0.047 13.5 2.7 0.79 9.6 0.1 2.7 2 0 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain DUF4132 PF13569.6 EST46920.1 - 0.075 12.8 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4132) Phage_Gp17 PF17549.2 EST46920.1 - 0.085 12.9 0.5 0.24 11.4 0.1 1.9 2 0 0 2 2 2 0 Gene Product 17 FPP PF05911.11 EST46922.1 - 0.00083 17.7 9.5 0.00087 17.6 9.5 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil V_ATPase_I PF01496.19 EST46922.1 - 0.0051 14.8 8.7 0.0056 14.7 8.7 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family RB_A PF01858.17 EST46922.1 - 0.0061 16.4 3.8 0.0073 16.2 3.8 1.1 1 0 0 1 1 1 1 Retinoblastoma-associated protein A domain ACCA PF03255.14 EST46922.1 - 0.0072 16.2 3.0 0.0091 15.9 3.0 1.2 1 0 0 1 1 1 1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Med4 PF10018.9 EST46922.1 - 0.013 15.2 6.8 0.016 14.9 6.8 1.2 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Golgin_A5 PF09787.9 EST46922.1 - 0.021 14.3 9.8 0.022 14.3 9.8 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 TMPIT PF07851.13 EST46922.1 - 0.026 13.8 7.6 0.031 13.5 7.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein BLOC1_2 PF10046.9 EST46922.1 - 0.053 13.8 9.4 0.45 10.8 8.9 2.4 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc29 PF17082.5 EST46922.1 - 0.054 13.3 4.3 0.062 13.1 4.3 1.1 1 0 0 1 1 1 0 Spindle Pole Component 29 HXXSHH PF07586.11 EST46922.1 - 0.062 12.9 1.1 0.072 12.7 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) FapA PF03961.13 EST46922.1 - 0.07 11.7 8.2 0.079 11.6 8.2 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A MtrB PF05440.12 EST46922.1 - 0.076 13.4 0.2 3.9 7.9 0.0 2.1 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B MnmE_helical PF12631.7 EST46922.1 - 0.077 13.2 3.2 0.082 13.1 3.2 1.1 1 0 0 1 1 1 0 MnmE helical domain DUF4349 PF14257.6 EST46922.1 - 0.084 12.3 1.4 0.11 11.9 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) ParBc PF02195.18 EST46922.1 - 0.087 13.1 1.1 0.14 12.5 0.9 1.3 1 1 0 1 1 1 0 ParB-like nuclease domain DDE_Tnp_IS240 PF13610.6 EST46922.1 - 0.097 12.9 2.4 0.14 12.3 2.1 1.5 1 1 0 1 1 1 0 DDE domain SpoIISA_toxin PF14171.6 EST46922.1 - 0.12 12.1 5.0 0.14 11.9 5.0 1.2 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system Exonuc_VII_L PF02601.15 EST46922.1 - 0.25 10.9 4.8 0.26 10.8 4.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit MerR-DNA-bind PF09278.11 EST46922.1 - 0.29 11.7 4.3 13 6.5 0.2 2.4 1 1 1 2 2 2 0 MerR, DNA binding CCDC-167 PF15188.6 EST46922.1 - 0.3 11.5 8.8 3.7 7.9 8.8 2.3 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 YvrJ PF12841.7 EST46922.1 - 0.55 9.8 4.3 0.22 11.1 1.4 1.9 2 0 0 2 2 2 0 YvrJ protein family DUF724 PF05266.14 EST46922.1 - 0.63 9.8 9.4 0.82 9.5 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Cep57_CLD_2 PF14197.6 EST46922.1 - 0.69 10.1 7.8 2.7 8.1 0.2 2.9 1 1 3 4 4 4 0 Centrosome localisation domain of PPC89 Uso1_p115_C PF04871.13 EST46922.1 - 0.73 10.2 8.3 1.6 9.1 0.3 1.9 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region BssS PF13991.6 EST46922.1 - 0.74 9.9 3.1 0.77 9.9 0.8 2.0 1 1 1 2 2 2 0 BssS protein family TMF_DNA_bd PF12329.8 EST46922.1 - 1.4 9.0 13.4 0.47 10.5 7.4 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Med9 PF07544.13 EST46922.1 - 1.4 9.0 15.6 6.7 6.9 9.9 2.4 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF16 PF01519.16 EST46922.1 - 1.5 9.3 14.6 0.26 11.8 9.7 1.8 1 1 1 2 2 2 0 Protein of unknown function DUF16 Blo-t-5 PF11642.8 EST46922.1 - 1.6 8.7 9.4 2.7 8.0 1.5 2.1 1 1 1 2 2 2 0 Mite allergen Blo t 5 FlaC_arch PF05377.11 EST46922.1 - 1.6 9.2 12.2 1.9 8.9 2.7 2.6 1 1 0 2 2 2 0 Flagella accessory protein C (FlaC) SlyX PF04102.12 EST46922.1 - 2 9.1 15.6 0.78 10.4 8.3 2.4 1 1 2 3 3 3 0 SlyX DUF1664 PF07889.12 EST46922.1 - 2.1 8.4 8.5 3.3 7.7 8.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) ABC_tran_CTD PF16326.5 EST46922.1 - 2.6 8.3 11.4 59 4.0 11.3 2.7 1 1 1 2 2 2 0 ABC transporter C-terminal domain DUF4094 PF13334.6 EST46922.1 - 2.6 8.5 6.7 0.86 10.1 1.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) XhlA PF10779.9 EST46922.1 - 3.5 7.9 9.5 1.1 9.5 2.7 2.2 1 1 1 2 2 2 0 Haemolysin XhlA DUF3450 PF11932.8 EST46922.1 - 7.2 5.8 15.3 2.1 7.6 9.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) PI3K_C2 PF00792.24 EST46923.1 - 0.0042 17.0 0.6 2.2 8.2 0.2 2.4 2 0 0 2 2 2 2 Phosphoinositide 3-kinase C2 Myb_DNA-binding PF00249.31 EST46924.1 - 0.066 13.4 0.2 0.51 10.6 0.2 2.2 1 1 0 1 1 1 0 Myb-like DNA-binding domain HGTP_anticodon PF03129.20 EST46925.1 - 1.6e-21 76.2 1.6 4e-21 75.0 0.2 2.2 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EST46925.1 - 5e-13 49.4 0.0 5.7e-12 46.0 0.0 2.4 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF4850 PF16142.5 EST46925.1 - 0.0062 16.0 0.1 0.011 15.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4850) SulA PF03846.14 EST46926.1 - 0.026 14.5 0.1 0.041 13.8 0.1 1.4 1 0 0 1 1 1 0 Cell division inhibitor SulA GMAP PF06540.11 EST46926.1 - 0.16 12.0 0.1 11 6.1 0.0 2.9 2 1 1 3 3 3 0 Galanin message associated peptide (GMAP) DUF3997 PF13162.6 EST46927.1 - 0.018 15.3 0.1 0.029 14.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3997) TBP PF00352.21 EST46928.1 - 0.00017 21.4 0.1 0.0058 16.6 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) Flavodoxin_1 PF00258.25 EST46929.1 - 1.6e-11 44.6 0.8 1.8e-11 44.4 0.8 1.1 1 0 0 1 1 1 1 Flavodoxin DUF1428 PF07237.11 EST46929.1 - 0.011 16.0 0.1 0.022 15.0 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1428) zf-CHY PF05495.12 EST46930.1 - 1.4e-06 28.7 18.7 1.4e-06 28.7 18.7 4.4 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 EST46930.1 - 2.3e-05 24.6 10.8 2.3e-05 24.6 10.8 5.7 3 2 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 EST46930.1 - 7.5e-05 22.5 12.9 7.5e-05 22.5 12.9 6.0 4 2 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EST46930.1 - 0.00071 19.4 12.4 0.00071 19.4 12.4 5.2 5 4 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) HPS6 PF15702.5 EST46931.1 - 0.011 13.8 0.2 0.014 13.4 0.2 1.1 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 6 protein CEP63 PF17045.5 EST46934.1 - 0.035 14.0 10.5 0.049 13.5 10.5 1.5 1 1 0 1 1 1 0 Centrosomal protein of 63 kDa GLE1 PF07817.13 EST46934.1 - 0.16 11.2 5.7 0.16 11.2 5.7 1.1 1 0 0 1 1 1 0 GLE1-like protein DASH_Dad1 PF08649.10 EST46935.1 - 0.82 9.9 7.5 0.52 10.5 3.6 2.8 2 1 0 2 2 2 0 DASH complex subunit Dad1 Jnk-SapK_ap_N PF09744.9 EST46935.1 - 5.2 7.3 41.2 0.47 10.7 25.2 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 MatE PF01554.18 EST46936.1 - 1.8e-20 73.2 33.7 3e-16 59.5 13.3 2.3 2 0 0 2 2 2 2 MatE tRNA-synt_His PF13393.6 EST46937.1 - 1.1e-35 123.4 0.0 2.2e-35 122.4 0.0 1.5 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EST46937.1 - 4e-08 33.3 0.7 1.1e-07 31.8 0.1 2.2 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2 PF00152.20 EST46937.1 - 0.00099 18.3 0.0 0.003 16.7 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) HGTP_anticodon2 PF12745.7 EST46937.1 - 0.0055 16.2 0.4 0.012 15.1 0.4 1.6 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs NFACT-R_1 PF05670.13 EST46938.1 - 1.9e-35 121.8 0.0 3.5e-35 120.9 0.0 1.4 1 0 0 1 1 1 1 NFACT protein RNA binding domain DUF3734 PF12536.8 EST46938.1 - 0.0062 16.8 0.9 1.1 9.6 3.2 2.7 2 1 1 3 3 3 2 Patatin phospholipase RD3 PF14473.6 EST46938.1 - 0.011 15.6 1.9 0.02 14.7 1.9 1.4 1 0 0 1 1 1 0 RD3 protein Tubulin PF00091.25 EST46939.1 - 2.4e-40 138.8 0.0 4e-40 138.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 EST46939.1 - 0.0026 17.0 0.0 0.0038 16.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin like Protocadherin PF08374.11 EST46944.1 - 0.046 13.7 0.1 0.082 12.9 0.1 1.3 1 0 0 1 1 1 0 Protocadherin TMEM154 PF15102.6 EST46944.1 - 0.1 12.5 0.2 0.19 11.6 0.2 1.3 1 0 0 1 1 1 0 TMEM154 protein family Podoplanin PF05808.11 EST46944.1 - 0.25 11.5 0.9 0.44 10.6 0.9 1.4 1 0 0 1 1 1 0 Podoplanin DUF2970 PF11174.8 EST46944.1 - 0.56 10.1 8.2 0.94 9.4 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) Histone PF00125.24 EST46945.1 - 8.5e-12 45.6 1.0 4e-11 43.4 0.1 1.9 1 1 1 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EST46945.1 - 2.8e-08 33.9 0.1 5e-08 33.1 0.0 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-18kDa PF02269.16 EST46945.1 - 0.025 14.6 0.9 0.038 14.0 0.9 1.5 1 1 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Histone_H2A_C PF16211.5 EST46945.1 - 0.19 11.5 0.0 0.19 11.5 0.0 2.4 3 0 0 3 3 3 0 C-terminus of histone H2A Kinesin PF00225.23 EST46946.1 - 1.6e-109 365.8 1.7 1.6e-109 365.8 1.7 1.9 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EST46946.1 - 1.8e-27 96.1 0.5 1.8e-27 96.1 0.5 2.4 2 1 0 2 2 2 1 Microtubule binding DUF3851 PF12962.7 EST46946.1 - 0.18 12.1 0.6 0.42 10.9 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3851) Atg14 PF10186.9 EST46946.1 - 1.6 7.7 22.8 3.6 6.6 22.8 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DSPn PF14671.6 EST46947.1 - 2.7e-40 138.1 0.8 6.6e-40 136.8 0.0 2.1 3 0 0 3 3 3 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EST46947.1 - 1.7e-13 50.5 0.2 8.1e-13 48.3 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EST46947.1 - 1e-05 25.7 0.3 9.9e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 EST46947.1 - 2.4e-05 24.1 0.0 2.4e-05 24.1 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 EST46947.1 - 0.02 14.5 0.0 0.055 13.0 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EST46947.1 - 0.025 14.5 1.3 0.03 14.3 0.0 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family DUF442 PF04273.13 EST46947.1 - 0.035 14.2 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 Putative phosphatase (DUF442) Peptidase_S64 PF08192.11 EST46947.1 - 1.3 7.5 10.7 1.8 7.0 10.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 HEAT PF02985.22 EST46948.1 - 0.005 17.0 0.0 7.1 7.2 0.0 3.5 3 0 0 3 3 3 2 HEAT repeat Cnd1 PF12717.7 EST46948.1 - 0.0082 16.2 0.8 1.3 9.1 0.0 2.7 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 DNA_methylase PF00145.17 EST46948.1 - 0.051 12.9 0.3 0.075 12.4 0.3 1.2 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase Hist_deacetyl PF00850.19 EST46949.1 - 1.3e-79 267.9 0.0 1.7e-79 267.5 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DUF5491 PF17595.2 EST46949.1 - 0.026 14.9 0.1 0.085 13.2 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5491) Ubiquitin_3 PF14836.6 EST46950.1 - 0.009 16.0 2.1 0.16 12.0 0.6 2.9 2 0 0 2 2 2 1 Ubiquitin-like domain CEP209_CC5 PF16574.5 EST46950.1 - 0.013 15.7 3.8 0.013 15.7 3.8 4.1 3 1 2 5 5 5 0 Coiled-coil region of centrosome protein CE290 ApoO PF09769.9 EST46950.1 - 2.8 7.9 5.0 0.67 9.9 1.1 2.1 2 0 0 2 2 2 0 Apolipoprotein O HTH_23 PF13384.6 EST46951.1 - 0.00094 18.9 0.0 0.0019 17.9 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain Ribosomal_L23 PF00276.20 EST46951.1 - 0.12 12.8 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L23 CoA_binding_2 PF13380.6 EST46952.1 - 0.13 12.8 0.0 0.13 12.7 0.0 1.1 1 0 0 1 1 1 0 CoA binding domain DUF4418 PF14387.6 EST46953.1 - 0.049 13.8 0.2 0.055 13.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4418) CLIP_SPH_Scar PF18399.1 EST46954.1 - 0.081 13.0 0.2 22 5.3 0.0 2.4 2 0 0 2 2 2 0 Clip-domain serine protease homolog Scarface DUF2593 PF10767.9 EST46954.1 - 0.25 11.4 3.2 0.4 10.7 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2593) RecG_N PF17190.4 EST46954.1 - 1 10.1 14.0 3.4 8.5 0.2 6.0 3 2 3 6 6 6 0 RecG N-terminal helical domain RRM_1 PF00076.22 EST46957.1 - 0.0081 16.0 0.7 0.05 13.4 0.5 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Baculo_PEP_N PF04512.12 EST46957.1 - 0.057 13.7 0.8 0.16 12.2 0.8 1.8 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, N terminus CRT-like PF08627.10 EST46959.1 - 2.5e-06 26.7 6.4 4.7e-06 25.8 6.4 1.5 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 EST46959.1 - 3.7e-06 27.1 18.9 7.2e-05 23.0 3.8 2.6 2 1 0 2 2 2 2 EamA-like transporter family SLC35F PF06027.12 EST46959.1 - 0.00011 21.8 9.4 0.0012 18.4 6.4 2.6 1 1 1 2 2 2 1 Solute carrier family 35 Nuc_sug_transp PF04142.15 EST46959.1 - 0.0014 17.9 0.7 0.0014 17.9 0.7 1.7 2 0 0 2 2 2 1 Nucleotide-sugar transporter PUNUT PF16913.5 EST46959.1 - 0.0019 17.5 4.6 0.0019 17.5 4.6 1.7 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport HupE_UreJ PF04955.12 EST46959.1 - 0.59 9.6 3.0 5.2 6.5 0.0 2.9 2 1 1 3 3 3 0 HupE / UreJ protein CAAD PF14159.6 EST46959.1 - 0.63 9.9 3.5 1.7 8.6 0.6 3.0 3 1 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF3185 PF11381.8 EST46959.1 - 1.7 8.7 5.9 8.7 6.4 0.9 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3185) Herpes_U5 PF05999.11 EST46960.1 - 0.075 11.8 0.0 0.085 11.6 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus U5-like family RNase_H2_suC PF08615.11 EST46960.1 - 0.1 12.8 0.1 0.22 11.7 0.1 1.6 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Ribosomal_L5_C PF00673.21 EST46961.1 - 9.8e-18 64.1 0.0 1.5e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EST46961.1 - 3.5e-16 59.3 0.1 5.9e-16 58.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 Ribosomal_S11 PF00411.19 EST46966.1 - 7.4e-32 110.0 1.1 9.3e-32 109.7 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Bac_small_YrzI PF09501.10 EST46967.1 - 0.039 14.1 0.1 0.05 13.8 0.1 1.1 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) NAD_binding_8 PF13450.6 EST46968.1 - 0.23 11.7 1.9 0.42 10.9 1.9 1.4 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Sushi PF00084.20 EST46968.1 - 0.49 11.0 4.5 0.56 10.9 1.1 2.6 1 1 1 2 2 2 0 Sushi repeat (SCR repeat) SVWC PF15430.6 EST46968.1 - 0.71 10.2 9.8 6.9 7.0 1.2 3.1 2 1 1 3 3 3 0 Single domain von Willebrand factor type C STI1 PF17830.1 EST46969.1 - 0.15 12.0 0.3 0.64 10.0 0.0 2.2 2 0 0 2 2 2 0 STI1 domain PCRF PF03462.18 EST46969.1 - 0.32 10.8 1.2 0.74 9.7 1.2 1.6 1 0 0 1 1 1 0 PCRF domain ER PF01133.17 EST46969.1 - 0.34 10.9 3.4 34 4.6 0.0 4.2 5 1 0 5 5 5 0 Enhancer of rudimentary Brix PF04427.18 EST46970.1 - 3.1e-18 66.6 0.4 3.1e-18 66.6 0.4 1.5 2 0 0 2 2 2 1 Brix domain Tugs PF17840.1 EST46970.1 - 0.065 13.4 0.2 0.19 11.9 0.2 1.7 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain DUF5542 PF17696.1 EST46970.1 - 0.11 12.6 0.4 0.27 11.4 0.4 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5542) DrsE_2 PF13686.6 EST46971.1 - 1.4 8.8 5.4 14 5.6 0.6 3.3 2 2 0 2 2 2 0 DsrE/DsrF/DrsH-like family Myb_DNA-binding PF00249.31 EST46972.1 - 5.4e-06 26.5 0.0 9.9e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain RRP36 PF06102.12 EST46972.1 - 0.31 11.0 2.6 5.2 7.0 0.2 2.1 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 ZapB PF06005.12 EST46972.1 - 2 8.9 5.6 0.83 10.1 1.5 2.3 2 1 0 2 2 2 0 Cell division protein ZapB eIF-5a PF01287.20 EST46973.1 - 8.5e-07 29.0 0.0 1.2e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold fn3_3 PF14686.6 EST46973.1 - 0.074 12.8 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain II PPDK_N PF01326.19 EST46974.1 - 0.015 14.6 0.3 0.015 14.6 0.3 1.1 1 0 0 1 1 1 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain SelR PF01641.18 EST46975.1 - 1.2e-35 122.2 0.0 1.3e-35 122.0 0.0 1.0 1 0 0 1 1 1 1 SelR domain Tnp_zf-ribbon_2 PF13842.6 EST46975.1 - 0.044 14.6 0.9 0.12 13.2 0.1 2.0 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon HECT_2 PF09814.9 EST46975.1 - 0.09 11.6 0.1 0.33 9.7 0.0 1.7 1 1 1 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Focal_AT PF03623.13 EST46977.1 - 0.056 13.4 0.0 0.071 13.1 0.0 1.1 1 0 0 1 1 1 0 Focal adhesion targeting region SelR PF01641.18 EST46980.1 - 1.2e-35 122.2 0.0 1.3e-35 122.0 0.0 1.0 1 0 0 1 1 1 1 SelR domain Tnp_zf-ribbon_2 PF13842.6 EST46980.1 - 0.044 14.6 0.9 0.12 13.2 0.1 2.0 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon HECT_2 PF09814.9 EST46980.1 - 0.09 11.6 0.1 0.33 9.7 0.0 1.7 1 1 1 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Sigma_reg_N PF13800.6 EST46981.1 - 9e-05 22.7 0.1 0.00012 22.3 0.1 1.1 1 0 0 1 1 1 1 Sigma factor regulator N-terminal Amnionless PF14828.6 EST46981.1 - 0.19 10.5 0.0 0.2 10.4 0.0 1.0 1 0 0 1 1 1 0 Amnionless DLL_N PF12413.8 EST46983.1 - 0.2 12.9 3.0 0.35 12.1 3.0 1.3 1 0 0 1 1 1 0 Homeobox protein distal-less-like N terminal Pyrid_ox_like PF16242.5 EST46985.1 - 0.00047 19.8 0.0 0.00055 19.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 EST46985.1 - 0.0039 17.4 0.0 0.0057 16.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PIN_6 PF17146.4 EST46986.1 - 5.7e-17 62.0 0.0 1e-15 58.0 0.0 2.4 2 0 0 2 2 2 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 EST46986.1 - 2.5e-08 34.0 0.3 4.3e-07 30.0 0.3 2.5 1 1 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zf-rbx1 PF12678.7 EST46987.1 - 4e-16 59.0 15.4 4.9e-16 58.8 15.4 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EST46987.1 - 5.9e-12 45.5 9.3 7e-12 45.2 9.3 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 EST46987.1 - 8e-11 42.1 11.3 8e-11 42.1 11.3 2.0 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EST46987.1 - 2.5e-06 27.3 11.6 2.5e-06 27.3 11.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EST46987.1 - 3e-06 27.0 11.9 3e-06 27.0 11.9 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EST46987.1 - 7.5e-05 22.5 18.4 0.00069 19.4 6.5 2.1 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EST46987.1 - 0.00038 20.3 8.5 0.00038 20.3 8.5 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EST46987.1 - 0.0014 18.6 6.1 0.0014 18.6 6.1 2.7 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 EST46987.1 - 0.0058 16.6 18.5 0.58 10.2 18.9 2.5 1 1 1 2 2 2 1 zinc-RING finger domain zf-HIT PF04438.16 EST46987.1 - 0.014 15.2 0.4 0.014 15.2 0.4 2.5 3 1 0 3 3 3 0 HIT zinc finger zf-RING_11 PF17123.5 EST46987.1 - 0.016 14.9 7.5 0.016 14.9 7.5 2.9 3 0 0 3 3 3 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 EST46987.1 - 0.05 13.2 15.8 0.049 13.3 10.7 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 EST46987.1 - 0.073 13.2 15.4 0.079 13.1 10.3 2.7 1 1 2 3 3 3 0 zinc finger of C3HC4-type, RING zinc_ribbon_16 PF17034.5 EST46987.1 - 0.23 11.7 10.8 1.1 9.5 4.2 2.1 1 1 1 2 2 2 0 Zinc-ribbon like family Zn-C2H2_12 PF18112.1 EST46987.1 - 0.24 11.9 0.3 0.24 11.9 0.3 2.9 4 0 0 4 4 2 0 Autophagy receptor zinc finger-C2H2 domain zf-RING-like PF08746.11 EST46987.1 - 1.2 9.5 17.8 0.086 13.2 11.8 2.0 2 0 0 2 2 2 0 RING-like domain DZR PF12773.7 EST46987.1 - 3.2 7.9 13.8 8.4 6.5 7.3 2.2 1 1 1 2 2 2 0 Double zinc ribbon ADK_lid PF05191.14 EST46987.1 - 3.4 7.7 9.6 2.8 8.0 0.6 2.7 3 0 0 3 3 2 0 Adenylate kinase, active site lid RecR PF02132.15 EST46987.1 - 3.5 7.3 16.0 1.2 8.7 0.2 3.4 3 1 1 4 4 4 0 RecR protein FANCL_C PF11793.8 EST46987.1 - 5.3 7.3 15.9 81 3.5 15.9 2.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.8 EST46987.1 - 8.3 6.3 13.1 83 3.1 12.9 2.1 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit MFS_1 PF07690.16 EST46989.1 - 0.039 12.9 43.2 0.64 8.9 41.1 2.4 1 1 0 1 1 1 0 Major Facilitator Superfamily HmuY PF14064.6 EST46990.1 - 0.091 13.0 0.0 0.091 13.0 0.0 3.0 3 1 0 3 3 3 0 HmuY protein DUF5082 PF16888.5 EST46991.1 - 0.019 15.2 1.3 0.046 14.0 1.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) GIT_CC PF16559.5 EST46991.1 - 0.57 10.1 5.9 1.6 8.7 5.9 1.7 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor RIIa PF02197.17 EST46992.1 - 2.7e-09 36.5 0.0 3.2e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Myb_DNA-bind_6 PF13921.6 EST46995.1 - 1.4e-12 47.7 6.9 3.1e-06 27.3 0.9 3.3 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EST46995.1 - 9.1e-09 35.4 6.3 1.2e-07 31.8 0.4 2.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EST46995.1 - 0.035 14.3 6.8 2.3 8.5 0.1 2.3 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 DUF3007 PF11460.8 EST46995.1 - 0.16 12.2 2.9 7.8 6.8 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) Rap1_C PF11626.8 EST46995.1 - 0.3 11.2 2.6 0.32 11.1 0.8 1.9 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain MT-A70 PF05063.14 EST46996.1 - 0.01 15.8 0.3 0.014 15.3 0.0 1.5 2 0 0 2 2 2 1 MT-A70 Acetyltransf_1 PF00583.25 EST46997.1 - 2.8e-17 63.0 0.0 3.6e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EST46997.1 - 6.4e-10 39.3 0.2 9.8e-10 38.7 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EST46997.1 - 1.3e-08 34.8 0.2 1.7e-08 34.4 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EST46997.1 - 2.6e-08 33.7 0.0 3.9e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EST46997.1 - 3.8e-07 30.9 0.0 4.8e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EST46997.1 - 1.1e-05 25.2 0.0 1.6e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EST46997.1 - 1.2e-05 25.5 1.1 1.6e-05 25.1 1.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EST46997.1 - 0.00017 21.7 0.0 0.00022 21.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NAT PF04768.13 EST46997.1 - 0.037 13.7 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 NAT, N-acetyltransferase, of N-acetylglutamate synthase Pfk_N PF18468.1 EST46997.1 - 0.054 13.9 0.1 0.1 13.0 0.1 1.4 1 0 0 1 1 1 0 Phosphofructokinase N-terminal domain yeast Acetyltransf_18 PF18014.1 EST46997.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4603 PF15376.6 EST46998.1 - 5 4.4 6.8 0.65 7.3 2.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4603) MKT1_N PF12247.8 EST46998.1 - 8.2 6.9 7.5 14 6.2 0.0 4.1 4 0 0 4 4 4 0 Temperature dependent protein affecting M2 dsRNA replication WD40 PF00400.32 EST46999.1 - 9.7e-09 35.7 0.2 0.00053 20.7 0.1 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat Asparaginase PF00710.20 EST46999.1 - 0.018 14.6 0.0 0.053 13.1 0.0 1.7 2 0 0 2 2 2 0 Asparaginase, N-terminal CK_II_beta PF01214.18 EST47000.1 - 1e-36 126.5 0.8 1.2e-36 126.3 0.8 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit L51_S25_CI-B8 PF05047.16 EST47002.1 - 0.0047 16.8 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain GvpL_GvpF PF06386.11 EST47002.1 - 0.025 14.5 5.3 0.021 14.8 3.7 1.7 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Ada3 PF10198.9 EST47002.1 - 0.4 10.8 20.8 0.026 14.7 13.9 2.4 1 1 1 2 2 2 0 Histone acetyltransferases subunit 3 HCNGP PF07818.13 EST47002.1 - 0.53 11.0 10.2 0.58 10.9 5.0 3.2 1 1 1 2 2 2 0 HCNGP-like protein YjcZ PF13990.6 EST47002.1 - 0.54 9.6 13.4 0.2 11.0 3.5 2.4 1 1 1 2 2 2 0 YjcZ-like protein Csm1_N PF18504.1 EST47002.1 - 1.6 9.2 28.6 0.85 10.0 3.1 5.1 3 1 1 4 4 4 0 Csm1 N-terminal domain DUF1325 PF07039.11 EST47002.1 - 8.5 6.5 10.6 1.8 8.7 0.4 3.1 3 0 0 3 3 3 0 SGF29 tudor-like domain CLP_protease PF00574.23 EST47003.1 - 1.2 9.0 9.3 0.21 11.4 5.0 1.9 1 1 0 1 1 1 0 Clp protease Peptidase_S46 PF10459.9 EST47003.1 - 3.1 6.3 30.4 4.1 5.9 30.4 1.1 1 0 0 1 1 1 0 Peptidase S46 AMPK1_CBM PF16561.5 EST47004.1 - 1.8e-18 66.5 0.3 2e-18 66.3 0.3 1.0 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 EST47004.1 - 1.2e-05 25.6 0.2 1.5e-05 25.3 0.2 1.2 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) TbpB_C PF17483.2 EST47005.1 - 0.057 13.8 0.0 0.097 13.1 0.0 1.3 1 0 0 1 1 1 0 C-lobe handle domain of Tf-binding protein B Adap_comp_sub PF00928.21 EST47006.1 - 1e-51 175.9 1.9 1e-51 175.9 1.9 1.4 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EST47006.1 - 0.84 9.6 6.6 1.6 8.6 4.1 2.5 2 2 0 2 2 2 0 Clathrin adaptor complex small chain Pkinase PF00069.25 EST47008.1 - 2.1e-50 171.5 0.5 2.8e-50 171.1 0.5 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST47008.1 - 2.3e-39 135.2 0.1 2.9e-39 134.9 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EST47008.1 - 2.4e-05 23.8 0.1 4.8e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.9 EST47008.1 - 0.0031 17.0 2.5 0.037 13.6 0.2 2.2 1 1 1 2 2 2 1 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 EST47008.1 - 0.026 13.3 0.0 0.039 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Multi_ubiq PF14452.6 EST47008.1 - 0.12 12.6 0.0 0.79 10.0 0.0 2.2 2 0 0 2 2 2 0 Multiubiquitin GATase PF00117.28 EST47009.1 - 1.7e-35 122.6 0.1 2.6e-35 122.0 0.1 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CTP_synth_N PF06418.14 EST47009.1 - 1.2e-19 70.6 0.5 1.9e-19 70.1 0.5 1.3 1 0 0 1 1 1 1 CTP synthase N-terminus Peptidase_C26 PF07722.13 EST47009.1 - 0.0011 18.8 0.6 0.018 14.8 0.3 2.6 2 1 0 2 2 2 1 Peptidase C26 EF-hand_1 PF00036.32 EST47010.1 - 3.5e-15 54.3 5.6 9.8e-07 27.9 0.7 3.7 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 EST47010.1 - 5.1e-12 46.1 2.2 5.1e-11 42.9 0.9 2.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 EST47010.1 - 9.5e-12 43.9 2.9 1.3e-05 24.7 0.3 3.8 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 EST47010.1 - 1.7e-10 40.6 4.6 0.0006 19.6 0.0 4.0 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 EST47010.1 - 3.8e-10 38.8 3.4 0.00038 19.8 0.4 3.1 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.7 EST47010.1 - 0.00066 19.6 2.5 0.79 9.7 0.1 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EST47010.1 - 0.028 14.8 0.1 0.062 13.6 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain SPARC_Ca_bdg PF10591.9 EST47010.1 - 0.042 14.2 0.0 0.12 12.7 0.0 1.7 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Filament PF00038.21 EST47011.1 - 0.47 10.0 48.5 0.0087 15.7 36.4 2.5 1 1 1 2 2 2 0 Intermediate filament protein SNF2_N PF00176.23 EST47014.1 - 1.2e-37 129.4 13.4 8e-33 113.6 0.1 3.2 4 0 0 4 4 4 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EST47014.1 - 1.4e-19 70.4 0.5 1.4e-19 70.4 0.5 3.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Chromo PF00385.24 EST47014.1 - 7.8e-15 54.5 1.8 1.5e-07 31.2 0.1 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 EST47014.1 - 7e-08 32.6 3.5 1.1e-07 32.0 0.1 3.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2120 PF09893.9 EST47014.1 - 0.97 9.5 5.1 19 5.4 0.1 3.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) Histone_HNS PF00816.21 EST47014.1 - 5.5 7.9 10.8 18 6.3 3.2 3.4 2 1 1 3 3 3 0 H-NS histone family IL4 PF00727.18 EST47017.1 - 0.078 13.2 0.1 1.7 8.9 0.1 2.7 2 0 0 2 2 2 0 Interleukin 4 DUF5064 PF16703.5 EST47018.1 - 0.66 10.5 4.1 2.3 8.7 0.3 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5064) Synaptobrevin PF00957.21 EST47020.1 - 2.2e-11 43.4 0.4 2.2e-11 43.4 0.4 1.6 2 0 0 2 2 2 1 Synaptobrevin DUF4904 PF16247.5 EST47020.1 - 0.055 13.3 0.0 0.081 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4904) LPD3 PF18798.1 EST47020.1 - 0.061 13.6 0.6 0.12 12.6 0.6 1.5 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 3 T3SS_basalb_I PF17001.5 EST47021.1 - 0.031 14.8 0.3 0.076 13.6 0.0 1.8 2 1 0 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI CSF-1 PF05337.11 EST47022.1 - 0.013 15.6 1.4 0.92 9.6 0.1 2.1 1 1 1 2 2 2 0 Macrophage colony stimulating factor-1 (CSF-1) Myb_DNA-binding PF00249.31 EST47023.1 - 9.8e-22 76.9 4.3 1.2e-11 44.6 0.3 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST47023.1 - 7.3e-18 64.6 8.3 8e-12 45.2 0.7 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EST47023.1 - 1.3e-06 28.4 0.6 0.0075 16.3 0.0 2.2 1 1 1 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 EST47023.1 - 0.0083 16.3 4.0 0.14 12.3 0.9 2.2 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 EST47023.1 - 0.058 13.8 3.9 0.52 10.7 0.8 2.9 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain YabA PF06156.13 EST47026.1 - 0.079 13.6 7.0 0.099 13.3 7.0 1.3 1 0 0 1 1 1 0 Initiation control protein YabA NAD_binding_3 PF03447.16 EST47026.1 - 0.099 13.3 0.1 0.11 13.1 0.1 1.2 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain SLATT_fungal PF18142.1 EST47026.1 - 0.13 12.2 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain Paralemmin PF03285.15 EST47026.1 - 0.37 10.3 4.2 0.47 10.0 4.2 1.0 1 0 0 1 1 1 0 Paralemmin Herpes_IE2_3 PF03361.14 EST47027.1 - 0.064 13.1 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Herpes virus intermediate/early protein 2/3 DUF713 PF05218.14 EST47028.1 - 0.018 14.8 3.9 0.034 13.9 3.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF713) HisKA_3 PF07730.13 EST47028.1 - 0.29 11.7 1.8 2.5 8.7 0.1 2.4 2 1 0 2 2 2 0 Histidine kinase Cpn60_TCP1 PF00118.24 EST47029.1 - 2.5e-143 478.3 18.5 2.9e-143 478.0 18.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HSP70 PF00012.20 EST47030.1 - 2.8e-13 48.9 2.2 3.1e-13 48.8 2.2 1.0 1 0 0 1 1 1 1 Hsp70 protein PMBR PF09373.10 EST47030.1 - 0.012 15.7 0.0 7 7.0 0.0 2.4 2 0 0 2 2 2 0 Pseudomurein-binding repeat Glu-tRNAGln PF02686.15 EST47030.1 - 0.087 13.1 5.3 0.27 11.6 0.2 2.9 3 0 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit ArlS_N PF18719.1 EST47030.1 - 0.43 10.8 2.3 2.2 8.5 0.1 2.0 2 0 0 2 2 2 0 ArlS sensor domain TM2 PF05154.16 EST47031.1 - 5.3e-08 33.1 14.4 7.1e-08 32.7 14.4 1.2 1 0 0 1 1 1 1 TM2 domain NTNH_C PF08470.10 EST47032.1 - 0.1 12.5 5.6 0.028 14.3 1.7 1.8 2 0 0 2 2 2 0 Nontoxic nonhaemagglutinin C-terminal DUF4326 PF14216.6 EST47033.1 - 0.075 13.8 0.3 0.21 12.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4326) RNA_pol_Rpb2_1 PF04563.15 EST47033.1 - 0.27 10.7 5.3 0.15 11.5 3.4 1.5 1 1 1 2 2 2 0 RNA polymerase beta subunit LMBR1 PF04791.16 EST47033.1 - 2.2 7.1 9.9 2.7 6.8 9.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein PMSI1 PF15322.6 EST47033.1 - 3.5 7.0 7.7 5.2 6.4 7.7 1.2 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Ycf66_N PF07444.11 EST47034.1 - 0.33 11.1 4.5 2.8 8.1 0.3 2.5 1 1 1 2 2 2 0 Ycf66 protein N-terminus DUF4374 PF14298.6 EST47038.1 - 0.043 12.6 1.4 0.057 12.2 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4374) BMFP PF04380.13 EST47039.1 - 0.0088 16.5 0.4 0.0088 16.5 0.4 2.0 2 0 0 2 2 2 1 Membrane fusogenic activity RNA_pol_Rpb2_1 PF04563.15 EST47039.1 - 0.12 11.9 1.6 0.23 11.0 1.6 1.5 1 0 0 1 1 1 0 RNA polymerase beta subunit DivIC PF04977.15 EST47039.1 - 9 6.2 9.3 4.7 7.1 1.8 3.5 3 0 0 3 3 3 0 Septum formation initiator Tubulin PF00091.25 EST47042.1 - 1e-68 231.4 0.0 1.7e-68 230.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EST47042.1 - 1.8e-40 138.0 0.0 2.7e-40 137.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EST47042.1 - 5.1e-05 23.6 0.0 0.00021 21.6 0.0 1.9 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EST47042.1 - 0.0045 16.7 0.0 0.0082 15.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 EST47042.1 - 0.014 14.6 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 Tubulin like Myb_DNA-binding PF00249.31 EST47044.1 - 2.5e-13 50.0 0.4 2.5e-08 34.0 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST47044.1 - 5.1e-08 33.1 2.0 2.2e-06 27.8 0.2 2.3 2 1 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST47044.1 - 1.6e-07 31.1 1.0 5.1e-06 26.3 0.2 2.4 1 1 1 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 EST47044.1 - 0.0013 19.1 0.5 0.9 10.0 0.1 2.5 1 1 1 2 2 2 2 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 EST47044.1 - 0.003 17.7 2.0 0.028 14.6 1.4 2.3 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 HAUS5 PF14817.6 EST47044.1 - 0.028 13.2 0.7 0.036 12.8 0.7 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 HTH_37 PF13744.6 EST47045.1 - 0.1 12.6 0.1 7.1 6.7 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain DUF5000 PF16391.5 EST47047.1 - 0.015 15.4 0.0 0.054 13.6 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function DUF765 PF05570.11 EST47048.1 - 0.0029 17.8 0.3 0.0029 17.8 0.3 3.5 3 0 0 3 3 3 1 Circovirus protein of unknown function (DUF765) CiPC PF15800.5 EST47048.1 - 4.7 6.8 10.9 6.3 6.4 10.9 1.1 1 0 0 1 1 1 0 Clock interacting protein circadian WD40 PF00400.32 EST47049.1 - 1.1e-07 32.4 0.0 0.017 16.0 0.0 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EST47049.1 - 0.003 17.8 0.0 0.39 11.0 0.0 3.6 3 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EST47049.1 - 0.42 11.2 2.9 4.4 7.9 0.0 3.5 4 0 0 4 4 4 0 PQQ-like domain PQQ PF01011.21 EST47049.1 - 0.55 10.3 5.2 5.9 7.0 0.0 3.7 4 0 0 4 4 4 0 PQQ enzyme repeat Pkinase PF00069.25 EST47050.1 - 6.3e-64 215.9 1.6 7.7e-64 215.6 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST47050.1 - 6.5e-41 140.3 0.0 1.5e-40 139.1 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase BRCA-2_OB3 PF09104.10 EST47051.1 - 0.069 12.8 2.4 2.6 7.7 0.2 2.5 2 1 0 2 2 2 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 Inhibitor_I69 PF13734.6 EST47054.1 - 0.056 13.9 0.1 0.12 12.7 0.0 1.5 1 1 1 2 2 2 0 Spi protease inhibitor Vps16_C PF04840.12 EST47055.1 - 0.056 12.5 0.0 0.082 11.9 0.0 1.2 1 0 0 1 1 1 0 Vps16, C-terminal region Put_Phosphatase PF06888.12 EST47058.1 - 0.023 14.1 2.5 0.075 12.4 0.0 2.4 1 1 2 3 3 3 0 Putative Phosphatase Mrpl_C PF18502.1 EST47058.1 - 0.079 13.2 0.7 1.1 9.6 0.1 2.4 2 0 0 2 2 2 0 54S ribosomal protein L8 C-terminal domain Mob1_phocein PF03637.17 EST47063.1 - 9e-13 48.6 5.9 5.4e-12 46.0 5.9 1.9 1 1 0 1 1 1 1 Mob1/phocein family Peptidase_C1 PF00112.23 EST47064.1 - 9e-12 45.5 0.0 1.2e-11 45.2 0.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Myb_DNA-binding PF00249.31 EST47066.1 - 0.11 12.8 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Myb-like DNA-binding domain ParD_like PF11903.8 EST47066.1 - 0.16 12.1 0.1 0.29 11.2 0.0 1.5 2 0 0 2 2 2 0 ParD-like antitoxin of type II bacterial toxin-antitoxin system DHHC PF01529.20 EST47067.1 - 1.4e-29 102.9 11.6 1.4e-29 102.9 11.6 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase PrgI PF12666.7 EST47067.1 - 0.43 11.3 3.7 14 6.5 0.8 3.1 3 0 0 3 3 3 0 PrgI family protein Seryl_tRNA_N PF02403.22 EST47068.1 - 8.7e-23 80.6 1.8 1.1e-21 77.1 3.3 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain tRNA-synt_2b PF00587.25 EST47068.1 - 1.1e-18 67.9 0.2 1.9e-16 60.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) DUF3450 PF11932.8 EST47068.1 - 0.017 14.4 0.6 0.03 13.6 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4349 PF14257.6 EST47068.1 - 0.045 13.2 0.8 0.083 12.3 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) ComA PF02679.15 EST47068.1 - 0.089 12.2 0.3 0.28 10.6 0.3 1.7 2 0 0 2 2 2 0 (2R)-phospho-3-sulfolactate synthase (ComA) DUF2203 PF09969.9 EST47068.1 - 0.11 13.2 0.3 0.29 11.9 0.3 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Myb_DNA-binding PF00249.31 EST47069.1 - 3.8e-06 27.0 0.4 6.5e-06 26.2 0.4 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST47069.1 - 0.0027 17.9 0.2 0.0035 17.6 0.2 1.3 1 1 0 1 1 1 1 Myb-like DNA-binding domain UMPH-1 PF05822.12 EST47069.1 - 0.074 12.5 0.1 0.082 12.4 0.1 1.0 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) ECR1_N PF14382.6 EST47070.1 - 3.6e-05 23.5 0.0 6.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Myb_DNA-binding PF00249.31 EST47076.1 - 2.4e-15 56.4 0.1 7.7e-10 38.8 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST47076.1 - 1.5e-12 47.6 0.0 6.8e-11 42.3 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EST47076.1 - 0.042 14.2 0.2 0.36 11.3 0.0 2.3 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Furin-like_2 PF15913.5 EST47078.1 - 0.0072 16.5 27.7 0.0072 16.5 27.7 6.1 2 1 4 6 6 6 2 Furin-like repeat, cysteine-rich Dynein_light PF01221.18 EST47078.1 - 0.3 11.4 2.8 0.5 10.7 1.0 2.2 2 0 0 2 2 2 0 Dynein light chain type 1 Dus PF01207.17 EST47080.1 - 4.6e-31 108.1 0.0 6.9e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) SNARE PF05739.19 EST47081.1 - 0.064 13.3 1.0 0.064 13.3 1.0 3.2 4 0 0 4 4 4 0 SNARE domain LRR_4 PF12799.7 EST47082.1 - 0.1 13.1 1.1 0.1 13.1 1.1 3.6 2 2 2 4 4 4 0 Leucine Rich repeats (2 copies) bZIP_2 PF07716.15 EST47082.1 - 0.15 12.2 0.8 0.36 11.0 0.8 1.6 1 0 0 1 1 1 0 Basic region leucine zipper EGF_2 PF07974.13 EST47084.1 - 0.00018 21.8 12.8 0.00018 21.8 12.8 10.7 7 1 2 9 9 9 5 EGF-like domain Laminin_EGF PF00053.24 EST47084.1 - 0.0022 18.1 10.8 0.0022 18.1 10.8 9.0 3 3 5 8 8 8 1 Laminin EGF domain Insulin_TMD PF17870.1 EST47084.1 - 0.054 13.6 1.0 0.11 12.6 1.0 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Syndecan PF01034.20 EST47084.1 - 0.13 12.2 0.2 0.27 11.2 0.2 1.5 1 0 0 1 1 1 0 Syndecan domain DUF5385 PF17359.2 EST47084.1 - 0.18 11.3 0.3 0.29 10.7 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) ASFV_J13L PF05568.11 EST47084.1 - 0.21 11.3 0.3 0.38 10.5 0.3 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF2335 PF10097.9 EST47085.1 - 0.013 15.4 0.1 0.021 14.8 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2335) RNase_T PF00929.24 EST47087.1 - 0.0098 16.5 0.3 3.8 8.0 0.0 2.3 2 0 0 2 2 2 2 Exonuclease hEGF PF12661.7 EST47089.1 - 0.011 16.4 2.7 0.011 16.4 2.7 6.2 5 2 0 5 5 5 0 Human growth factor-like EGF EGF_2 PF07974.13 EST47089.1 - 0.016 15.6 8.4 0.016 15.6 8.4 5.8 5 1 0 5 5 5 0 EGF-like domain S1FA PF04689.13 EST47089.1 - 0.022 14.9 0.0 0.037 14.2 0.0 1.2 1 0 0 1 1 1 0 DNA binding protein S1FA LPD14 PF18827.1 EST47091.1 - 2.8e-06 27.6 0.8 0.049 13.9 0.1 2.2 2 0 0 2 2 2 2 Large polyvalent protein-associated domain 14 Spc7 PF08317.11 EST47091.1 - 3.6e-05 22.8 32.1 0.0066 15.4 7.2 3.2 1 1 2 3 3 3 2 Spc7 kinetochore protein FlaC_arch PF05377.11 EST47091.1 - 6.8e-05 23.2 14.6 25 5.4 0.1 6.8 5 1 1 6 6 6 0 Flagella accessory protein C (FlaC) AAA_13 PF13166.6 EST47091.1 - 0.01 14.5 19.9 0.013 14.2 10.2 2.1 2 0 0 2 2 2 0 AAA domain DUF4795 PF16043.5 EST47091.1 - 0.013 15.1 21.1 94 2.5 19.9 3.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) HBM PF16591.5 EST47091.1 - 0.015 14.7 29.1 0.089 12.2 6.7 2.6 1 1 2 3 3 3 0 Helical bimodular sensor domain DUF1640 PF07798.11 EST47091.1 - 0.023 14.7 12.9 0.44 10.6 0.5 3.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) DUF3263 PF11662.8 EST47091.1 - 0.06 13.2 7.0 2.4 8.1 0.3 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3263) ALIX_LYPXL_bnd PF13949.6 EST47091.1 - 0.067 12.5 25.5 0.029 13.7 13.8 3.4 1 1 2 3 3 3 0 ALIX V-shaped domain binding to HIV DMPK_coil PF08826.10 EST47091.1 - 0.073 13.2 28.8 2.5 8.3 8.7 6.3 6 1 0 6 6 5 0 DMPK coiled coil domain like Bud13 PF09736.9 EST47091.1 - 0.12 12.8 12.4 0.74 10.2 0.9 2.8 1 1 1 3 3 3 0 Pre-mRNA-splicing factor of RES complex DUF848 PF05852.11 EST47091.1 - 0.12 12.5 18.7 0.22 11.6 4.7 4.0 1 1 3 4 4 4 0 Gammaherpesvirus protein of unknown function (DUF848) AKNA PF12443.8 EST47091.1 - 0.13 13.0 19.5 10 6.9 5.7 5.4 3 2 3 6 6 6 0 AT-hook-containing transcription factor YabA PF06156.13 EST47091.1 - 0.13 13.0 19.5 14 6.4 7.6 4.6 2 1 1 4 4 4 0 Initiation control protein YabA ZapB PF06005.12 EST47091.1 - 0.13 12.7 38.0 0.27 11.7 3.7 5.3 2 1 3 5 5 5 0 Cell division protein ZapB UDPG_MGDP_dh_C PF03720.15 EST47091.1 - 0.14 12.6 7.8 11 6.5 0.1 3.8 3 1 1 4 4 3 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Cas_DxTHG PF09455.10 EST47091.1 - 0.18 11.3 1.5 0.48 10.0 1.4 1.8 1 1 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family GAS PF13851.6 EST47091.1 - 0.24 10.7 27.6 1.8 7.9 5.7 3.4 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Toxin_YhaV PF11663.8 EST47091.1 - 0.33 11.0 6.9 6.5 6.8 0.2 3.3 3 0 0 3 3 3 0 Toxin with endonuclease activity, of toxin-antitoxin system FapA PF03961.13 EST47091.1 - 0.37 9.4 12.9 0.022 13.4 3.9 2.6 1 1 2 3 3 3 0 Flagellar Assembly Protein A Syntaxin-6_N PF09177.11 EST47091.1 - 0.4 11.3 22.4 30 5.3 0.6 5.8 1 1 3 4 4 4 0 Syntaxin 6, N-terminal Cytochrom_B562 PF07361.11 EST47091.1 - 0.43 11.3 20.8 0.14 12.8 3.2 4.3 1 1 3 4 4 3 0 Cytochrome b562 LPP PF04728.13 EST47091.1 - 0.64 10.5 17.2 6.2 7.3 0.3 5.9 4 2 1 5 5 5 0 Lipoprotein leucine-zipper Pox_Ag35 PF03286.14 EST47091.1 - 0.77 9.5 14.0 2.1 8.1 0.7 3.6 2 2 1 3 3 3 0 Pox virus Ag35 surface protein Jnk-SapK_ap_N PF09744.9 EST47091.1 - 0.97 9.6 28.9 4 7.7 3.5 3.8 2 2 1 3 3 3 0 JNK_SAPK-associated protein-1 Prefoldin_3 PF13758.6 EST47091.1 - 1 9.5 10.7 3 8.0 0.4 4.7 3 1 3 6 6 5 0 Prefoldin subunit FlxA PF14282.6 EST47091.1 - 1.3 9.0 32.0 6.3 6.8 0.1 5.3 3 2 2 5 5 5 0 FlxA-like protein Occludin_ELL PF07303.13 EST47091.1 - 1.5 9.6 9.1 4.3 8.1 0.7 4.0 1 1 4 5 5 5 0 Occludin homology domain Fib_alpha PF08702.10 EST47091.1 - 1.7 8.8 13.2 7.9 6.7 0.3 4.0 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family EFG_II PF14492.6 EST47091.1 - 1.7 8.8 10.7 7.9 6.6 0.3 4.2 4 0 0 4 4 4 0 Elongation Factor G, domain II Snapin_Pallidin PF14712.6 EST47091.1 - 1.7 9.1 26.1 2.2 8.8 2.8 4.6 3 2 1 5 5 5 0 Snapin/Pallidin bZIP_1 PF00170.21 EST47091.1 - 1.8 8.7 24.3 2.2 8.5 0.3 5.9 5 1 2 7 7 7 0 bZIP transcription factor YvrJ PF12841.7 EST47091.1 - 2 8.0 14.3 1.9 8.1 0.0 4.5 6 0 0 6 6 5 0 YvrJ protein family COG5 PF10392.9 EST47091.1 - 2.1 8.5 13.0 6.7 6.9 4.5 3.9 3 1 1 4 4 4 0 Golgi transport complex subunit 5 XPC-binding PF09280.11 EST47091.1 - 2.4 8.0 11.5 6.6 6.6 2.6 3.2 2 1 0 2 2 2 0 XPC-binding domain DASH_Dam1 PF08653.10 EST47091.1 - 2.7 7.8 11.8 37 4.2 0.1 5.6 5 1 1 6 6 5 0 DASH complex subunit Dam1 DUF3040 PF11239.8 EST47091.1 - 2.9 8.2 5.6 20 5.5 0.6 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DUF5082 PF16888.5 EST47091.1 - 3.2 8.1 20.3 17 5.7 1.0 5.4 3 2 2 5 5 5 0 Domain of unknown function (DUF5082) EMP24_GP25L PF01105.24 EST47091.1 - 3.3 7.6 12.2 4 7.3 0.9 3.3 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD TolA_bind_tri PF16331.5 EST47091.1 - 3.3 7.8 29.4 17 5.5 1.0 6.6 4 2 3 7 7 7 0 TolA binding protein trimerisation DUF724 PF05266.14 EST47091.1 - 4 7.2 14.3 11 5.8 0.3 3.5 1 1 1 3 3 3 0 Protein of unknown function (DUF724) Flagellin_N PF00669.20 EST47091.1 - 4.5 7.4 25.5 1.3 9.1 2.3 4.3 3 2 1 4 4 4 0 Bacterial flagellin N-terminal helical region Bcr-Abl_Oligo PF09036.10 EST47091.1 - 4.8 7.3 7.9 7.4 6.7 0.9 3.3 3 1 1 4 4 3 0 Bcr-Abl oncoprotein oligomerisation domain Myosin_tail_1 PF01576.19 EST47091.1 - 6.1 4.5 31.4 1.5 6.5 21.0 2.3 1 1 1 2 2 2 0 Myosin tail JIP_LZII PF16471.5 EST47091.1 - 8.3 6.7 19.3 12 6.2 0.5 5.4 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II XhlA PF10779.9 EST47091.1 - 8.5 6.7 12.6 70 3.7 0.4 5.1 5 0 0 5 5 5 0 Haemolysin XhlA DASH_Duo1 PF08651.10 EST47091.1 - 8.6 6.2 10.8 9.3 6.1 0.1 4.4 4 1 0 4 4 4 0 DASH complex subunit Duo1 TMPIT PF07851.13 EST47091.1 - 9.5 5.4 11.4 0.73 9.0 1.7 2.9 2 1 1 3 3 3 0 TMPIT-like protein Noelin-1 PF12308.8 EST47091.1 - 9.8 6.2 11.6 2.6 8.1 1.0 3.9 1 1 0 4 4 4 0 Neurogenesis glycoprotein Ank_2 PF12796.7 EST47092.1 - 8.8e-32 109.5 4.3 3.6e-12 46.7 0.2 4.9 1 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EST47092.1 - 3.4e-16 59.1 0.4 0.041 14.2 0.0 6.4 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EST47092.1 - 1.9e-15 55.4 0.6 0.027 15.0 0.0 7.7 8 0 0 8 8 8 4 Ankyrin repeat Ank_4 PF13637.6 EST47092.1 - 6.7e-15 55.3 2.0 0.00034 21.1 0.2 4.8 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 EST47092.1 - 1.5e-12 47.3 0.1 0.47 11.0 0.0 6.3 7 0 0 7 7 7 4 Ankyrin repeat Spc7 PF08317.11 EST47092.1 - 0.0044 15.9 71.1 0.006 15.5 15.1 5.1 1 1 2 4 4 4 2 Spc7 kinetochore protein TSC22 PF01166.18 EST47092.1 - 0.02 15.2 5.1 0.02 15.2 5.1 8.5 7 1 4 11 11 11 0 TSC-22/dip/bun family MerR-DNA-bind PF09278.11 EST47092.1 - 0.061 13.9 0.3 0.061 13.9 0.3 8.8 7 3 1 9 9 9 0 MerR, DNA binding GP17 PF17420.2 EST47092.1 - 0.81 9.9 3.7 2.6 8.2 3.7 1.9 1 0 0 1 1 1 0 Superinfection exclusion gene product 17 GIY-YIG PF01541.24 EST47093.1 - 1.7e-10 41.0 0.0 3.1e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain TFCD_C PF12612.8 EST47093.1 - 0.02 14.7 0.0 0.03 14.2 0.0 1.2 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal Herpes_BLRF2 PF05812.12 EST47094.1 - 0.012 15.7 5.7 1.4 9.1 0.1 3.8 3 2 0 3 3 3 0 Herpesvirus BLRF2 protein DUF4168 PF13767.6 EST47094.1 - 3.9 8.7 7.2 2.6 9.3 1.8 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4168) DUF148 PF02520.17 EST47094.1 - 7.6 6.7 11.7 0.11 12.6 0.9 2.9 3 1 0 3 3 3 0 Domain of unknown function DUF148 TB2_DP1_HVA22 PF03134.19 EST47095.1 - 3.9e-12 45.9 0.1 6.7e-12 45.2 0.1 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Acyl_transf_3 PF01757.22 EST47095.1 - 0.0032 16.6 0.8 0.0038 16.3 0.8 1.1 1 0 0 1 1 1 1 Acyltransferase family SHIPPO-rpt PF07004.12 EST47096.1 - 4.5e-25 87.3 52.7 6e-05 23.8 0.5 11.1 11 0 0 11 11 11 7 Sperm-tail PG-rich repeat ECR1_N PF14382.6 EST47096.1 - 0.00049 19.8 0.4 8.7 6.2 0.0 4.6 5 0 0 5 5 5 2 Exosome complex exonuclease RRP4 N-terminal region DUF3192 PF11399.8 EST47099.1 - 0.071 13.1 0.1 0.16 12.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3192) PHM7_cyt PF14703.6 EST47100.1 - 0.018 15.3 0.1 0.044 14.0 0.1 1.7 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DUF2025 PF09634.10 EST47102.1 - 0.083 12.9 0.2 1.2 9.1 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2025) Myb_DNA-bind_6 PF13921.6 EST47103.1 - 7.3e-12 45.4 0.3 3.8e-08 33.4 0.1 2.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EST47103.1 - 2.7e-11 43.5 0.9 1.6e-06 28.2 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Atg29_N PF18388.1 EST47103.1 - 0.09 12.6 1.9 1.8 8.4 0.4 2.2 2 0 0 2 2 2 0 Atg29 N-terminal domain DUF1686 PF07937.11 EST47104.1 - 0.04 13.8 1.3 0.063 13.2 0.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1686) TssN PF17555.2 EST47104.1 - 0.12 11.8 7.0 0.2 11.0 7.0 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF2070 PF09843.9 EST47104.1 - 0.9 7.7 5.5 1.2 7.3 5.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Phage_holin_3_6 PF07332.11 EST47104.1 - 2.2 8.4 7.3 0.86 9.7 2.9 2.4 2 2 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III ABC_tran PF00005.27 EST47105.1 - 8.6e-43 146.1 4.4 1.5e-21 77.4 0.0 3.9 4 1 0 4 4 4 2 ABC transporter ABC_tran_Xtn PF12848.7 EST47105.1 - 1.1e-17 63.8 0.1 1.1e-17 63.8 0.1 3.5 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.6 EST47105.1 - 6.3e-15 55.8 3.9 0.0098 15.7 0.1 4.7 3 2 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EST47105.1 - 5.1e-12 45.7 5.0 6.8e-05 22.4 0.1 4.1 3 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EST47105.1 - 0.00022 21.3 0.0 0.17 12.0 0.1 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 EST47105.1 - 0.00024 20.8 0.6 0.32 10.8 0.1 3.5 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EST47105.1 - 0.00025 21.3 1.0 0.26 11.5 0.0 3.8 3 2 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 EST47105.1 - 0.002 18.0 2.9 1 9.2 0.0 3.4 4 0 0 4 4 4 2 RsgA GTPase SbcCD_C PF13558.6 EST47105.1 - 0.0049 17.1 0.1 0.46 10.8 0.0 3.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 EST47105.1 - 0.021 14.4 0.0 4 7.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 EST47105.1 - 0.025 14.8 0.0 0.36 11.0 0.0 2.7 3 0 0 3 3 3 0 AAA domain MCM PF00493.23 EST47105.1 - 0.028 13.5 0.0 0.33 10.0 0.0 2.7 3 0 0 3 3 3 0 MCM P-loop domain AAA_18 PF13238.6 EST47105.1 - 0.031 14.8 1.0 2.9 8.4 0.0 3.6 4 0 0 4 4 4 0 AAA domain AAA_23 PF13476.6 EST47105.1 - 0.033 14.7 0.3 0.25 11.8 0.1 4.6 5 1 0 5 5 5 0 AAA domain AAA_24 PF13479.6 EST47105.1 - 0.05 13.3 0.1 3.4 7.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_27 PF13514.6 EST47105.1 - 0.085 12.4 0.9 5.6 6.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 EST47105.1 - 0.3 11.1 5.4 2.1 8.4 0.0 3.6 3 1 0 3 3 3 0 Dynamin family DUF3744 PF12558.8 EST47105.1 - 1.1 10.1 5.4 0.34 11.7 0.3 3.0 3 1 0 3 3 3 0 ATP-binding cassette cobalt transporter DUF2815 PF10991.8 EST47105.1 - 2.2 8.2 6.3 1.4 8.8 1.7 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2815) ThylakoidFormat PF11264.8 EST47107.1 - 0.013 15.2 9.6 0.14 11.8 0.2 2.5 1 1 1 2 2 2 0 Thylakoid formation protein Meth_synt_1 PF08267.12 EST47107.1 - 0.23 10.9 6.4 0.26 10.8 5.2 1.7 1 1 1 2 2 2 0 Cobalamin-independent synthase, N-terminal domain Bcr-Abl_Oligo PF09036.10 EST47107.1 - 9.6 6.3 9.3 1.3 9.1 0.5 3.2 2 1 1 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain SHIPPO-rpt PF07004.12 EST47108.1 - 0.0056 17.5 0.1 14 6.8 0.0 3.7 4 0 0 4 4 4 2 Sperm-tail PG-rich repeat Med17 PF10156.9 EST47108.1 - 0.014 14.1 0.1 0.017 13.9 0.1 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex DUF455 PF04305.14 EST47108.1 - 0.12 11.9 0.1 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF455) bZIP_1 PF00170.21 EST47110.1 - 0.0019 18.2 31.5 0.011 15.9 2.3 4.8 3 1 3 6 6 6 3 bZIP transcription factor ZapB PF06005.12 EST47110.1 - 0.019 15.4 11.2 0.019 15.4 11.2 4.3 2 1 2 4 4 4 0 Cell division protein ZapB DUF4164 PF13747.6 EST47110.1 - 0.076 13.3 4.8 0.081 13.2 1.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) DUF1845 PF08900.11 EST47110.1 - 0.077 12.7 5.2 0.12 12.1 4.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1845) TSC22 PF01166.18 EST47110.1 - 0.13 12.6 19.3 0.98 9.8 1.3 4.2 3 2 1 4 4 4 0 TSC-22/dip/bun family Jnk-SapK_ap_N PF09744.9 EST47110.1 - 0.2 11.9 39.9 0.18 12.0 10.6 3.4 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 LPP PF04728.13 EST47110.1 - 0.26 11.7 0.2 0.26 11.7 0.2 4.0 4 1 1 5 5 5 0 Lipoprotein leucine-zipper GAS PF13851.6 EST47110.1 - 1.2 8.4 37.7 0.49 9.7 26.0 2.4 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3450 PF11932.8 EST47110.1 - 6.5 6.0 34.8 0.61 9.3 11.3 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Mannitol_dh PF01232.23 EST47111.1 - 0.061 13.5 3.0 0.078 13.1 0.3 2.3 2 0 0 2 2 2 0 Mannitol dehydrogenase Rossmann domain ATG_C PF09333.11 EST47111.1 - 0.15 12.5 0.8 1.3 9.4 0.0 2.9 4 0 0 4 4 4 0 Autophagy-related protein C terminal domain Thioredoxin PF00085.20 EST47112.1 - 6.6e-33 112.8 0.3 7.4e-33 112.6 0.3 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EST47112.1 - 1.6e-08 34.9 0.2 4.8e-08 33.4 0.2 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EST47112.1 - 1e-06 28.8 0.1 1.4e-06 28.3 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 EST47112.1 - 0.0015 18.8 0.0 0.0042 17.4 0.0 1.7 1 1 1 2 2 2 1 Thioredoxin-like Redoxin PF08534.10 EST47112.1 - 0.008 15.9 0.2 0.0095 15.7 0.2 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EST47112.1 - 0.0095 15.9 0.2 0.013 15.4 0.2 1.4 1 1 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 EST47112.1 - 0.067 12.5 0.1 0.087 12.2 0.1 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 EST47112.1 - 0.08 12.7 0.0 0.09 12.6 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin HyaE PF07449.11 EST47112.1 - 0.14 12.2 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE SNARE PF05739.19 EST47114.1 - 8.3e-05 22.5 0.7 8.3e-05 22.5 0.7 3.4 4 0 0 4 4 4 1 SNARE domain V-SNARE PF05008.15 EST47114.1 - 0.00096 19.5 5.7 0.00096 19.5 5.7 2.6 2 1 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus DUF2207 PF09972.9 EST47114.1 - 0.073 11.8 1.8 0.21 10.3 1.8 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1664 PF07889.12 EST47114.1 - 0.39 10.8 10.9 3.2 7.8 5.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 EST47114.1 - 0.57 10.6 8.9 5.8 7.4 0.2 3.7 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) DASH_Duo1 PF08651.10 EST47114.1 - 0.67 9.8 9.9 4.3 7.2 0.2 3.6 3 2 2 5 5 5 0 DASH complex subunit Duo1 Syntaphilin PF15290.6 EST47114.1 - 1.1 8.8 13.4 0.29 10.7 8.5 1.9 1 1 1 2 2 2 0 Golgi-localised syntaxin-1-binding clamp Sec20 PF03908.13 EST47114.1 - 1.8 8.5 8.3 0.15 12.0 0.8 2.5 2 1 0 2 2 2 0 Sec20 PV-1 PF06637.11 EST47114.1 - 1.9 7.2 16.8 0.4 9.5 7.4 2.0 1 1 1 2 2 2 0 PV-1 protein (PLVAP) Rx_N PF18052.1 EST47114.1 - 2.4 8.5 9.4 2.1 8.7 3.9 2.7 2 1 0 2 2 2 0 Rx N-terminal domain Uso1_p115_C PF04871.13 EST47114.1 - 2.7 8.4 14.8 5.2 7.5 11.7 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region YppG PF14179.6 EST47114.1 - 3.7 8.3 5.0 0.76 10.5 0.8 2.0 2 1 0 2 2 2 0 YppG-like protein EMP24_GP25L PF01105.24 EST47114.1 - 4.9 7.1 13.3 0.14 12.1 0.5 2.5 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD CENP-F_leu_zip PF10473.9 EST47115.1 - 0.0063 16.5 5.2 0.0086 16.1 5.2 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc29 PF17082.5 EST47115.1 - 0.0093 15.8 1.1 0.012 15.4 1.1 1.4 1 0 0 1 1 1 1 Spindle Pole Component 29 CC2-LZ PF16516.5 EST47115.1 - 0.0095 16.3 0.4 0.0095 16.3 0.4 1.7 2 0 0 2 2 2 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF641 PF04859.12 EST47115.1 - 0.016 15.5 1.7 0.022 15.1 0.7 1.7 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) KASH_CCD PF14662.6 EST47115.1 - 0.026 14.3 4.4 0.036 13.9 4.4 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH UPF0242 PF06785.11 EST47115.1 - 0.71 10.0 6.6 0.63 10.1 1.5 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Ephrin_rec_like PF07699.13 EST47116.1 - 0.011 15.5 7.6 0.011 15.5 7.6 4.4 4 1 0 4 4 4 0 Putative ephrin-receptor like GF_recep_IV PF14843.6 EST47116.1 - 0.96 9.3 31.8 3 7.6 17.9 2.7 1 1 2 3 3 3 0 Growth factor receptor domain IV YfdX PF10938.8 EST47118.1 - 0.0031 17.4 5.7 0.0031 17.4 5.7 1.8 2 0 0 2 2 2 1 YfdX protein bZIP_1 PF00170.21 EST47118.1 - 0.19 11.9 6.4 1.8 8.8 1.9 2.9 2 0 0 2 2 2 0 bZIP transcription factor Arg_decarbox_C PF17944.1 EST47118.1 - 9.3 6.9 11.3 26 5.5 0.1 4.9 4 2 1 5 5 5 0 Arginine decarboxylase C-terminal helical extension Cep57_CLD_2 PF14197.6 EST47118.1 - 9.8 6.4 12.7 0.27 11.3 3.2 3.1 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 HU-CCDC81_bac_2 PF18175.1 EST47121.1 - 0.12 12.2 0.2 0.15 11.9 0.2 1.1 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 Aa_trans PF01490.18 EST47123.1 - 8.7e-10 37.9 34.0 1.4e-06 27.3 26.3 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein DEAD PF00270.29 EST47126.1 - 2.3e-45 154.5 0.2 6.6e-45 153.0 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EST47126.1 - 4e-30 104.4 2.1 1e-28 99.9 0.0 3.2 1 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EST47126.1 - 1.1e-05 25.6 0.0 4.4e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 EST47126.1 - 0.0072 15.6 0.0 0.032 13.5 0.0 1.9 1 1 0 1 1 1 1 SecA DEAD-like domain Palm_thioest PF02089.15 EST47128.1 - 5.6e-54 183.5 0.0 6.6e-54 183.3 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 EST47128.1 - 0.04 14.5 0.0 0.058 14.0 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Baculo_11_kDa PF06143.11 EST47128.1 - 0.2 11.2 1.3 0.38 10.4 1.3 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF4690 PF15756.5 EST47128.1 - 2.6 8.7 4.5 3.7 8.2 3.6 1.7 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Ndc1_Nup PF09531.10 EST47130.1 - 0.15 10.7 5.9 0.18 10.4 5.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Aa_trans PF01490.18 EST47131.1 - 1.3e-16 60.3 22.4 1.9e-16 59.8 22.4 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Sdh_cyt PF01127.22 EST47132.1 - 0.06 13.4 0.4 0.06 13.4 0.4 2.2 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Ribosomal_L22 PF00237.19 EST47134.1 - 5.2e-22 78.0 0.1 6.8e-22 77.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF1059 PF06348.11 EST47134.1 - 0.068 13.4 1.8 0.083 13.1 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1059) zf_CCCH_4 PF18345.1 EST47135.1 - 2.8e-07 30.3 1.1 4.7e-07 29.7 1.1 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 EST47135.1 - 4.3e-06 26.5 0.6 6.6e-06 25.9 0.6 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EST47135.1 - 6.4e-06 26.8 0.1 7.9e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 Torus domain zf-CCCH_4 PF18044.1 EST47135.1 - 1.7e-05 24.5 0.8 2.4e-05 24.0 0.8 1.2 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 EST47135.1 - 0.026 15.0 2.3 0.042 14.3 2.3 1.3 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Rad54_N PF08658.10 EST47135.1 - 0.045 13.9 0.1 0.053 13.7 0.1 1.1 1 0 0 1 1 1 0 Rad54 N terminal EAP30 PF04157.16 EST47138.1 - 1.7e-05 24.2 2.1 7.3e-05 22.2 2.1 1.9 1 1 0 1 1 1 1 EAP30/Vps36 family DUF2857 PF11198.8 EST47138.1 - 0.13 12.0 0.8 0.8 9.5 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2857) Peptidase_M3 PF01432.20 EST47142.1 - 1.7e-68 231.9 8.5 1.7e-68 231.9 8.5 1.5 2 0 0 2 2 2 1 Peptidase family M3 Exo_endo_phos PF03372.23 EST47143.1 - 0.00043 19.9 0.0 0.0013 18.3 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-MYND PF01753.18 EST47144.1 - 1.3e-08 34.8 15.4 1.3e-08 34.8 15.4 2.6 2 0 0 2 2 2 1 MYND finger Siva PF05458.12 EST47144.1 - 0.0064 16.2 1.6 0.0064 16.2 1.6 2.2 2 0 0 2 2 2 1 Cd27 binding protein (Siva) DNA_pol_viral_C PF00336.18 EST47144.1 - 0.036 13.5 0.4 0.5 9.7 0.1 2.2 2 0 0 2 2 2 0 DNA polymerase (viral) C-terminal domain Spectrin PF00435.21 EST47146.1 - 0.35 11.4 12.4 0.43 11.1 0.3 2.4 2 0 0 2 2 2 0 Spectrin repeat Sigma54_activ_2 PF14532.6 EST47148.1 - 1.3e-06 28.5 0.2 4.9e-06 26.7 0.1 2.0 2 0 0 2 2 2 1 Sigma-54 interaction domain T2SSE PF00437.20 EST47148.1 - 0.0015 17.6 0.0 0.0028 16.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein RuvB_N PF05496.12 EST47148.1 - 0.0015 18.3 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EST47148.1 - 0.0018 18.8 3.1 0.0027 18.2 0.1 2.8 3 1 0 3 3 3 1 AAA domain BRCT PF00533.26 EST47148.1 - 0.002 18.5 2.3 0.0051 17.2 0.3 2.7 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Ploopntkinase1 PF18748.1 EST47148.1 - 0.013 15.0 0.6 0.4 10.2 0.1 3.0 2 1 0 3 3 3 0 P-loop Nucleotide Kinase1 AAA_5 PF07728.14 EST47148.1 - 0.13 12.3 0.0 1 9.4 0.0 2.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_assoc_2 PF16193.5 EST47148.1 - 0.14 12.5 0.3 0.94 9.9 0.0 2.5 2 0 0 2 2 2 0 AAA C-terminal domain Pkinase PF00069.25 EST47149.1 - 1.2e-13 51.0 0.7 3.1e-13 49.7 0.7 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST47149.1 - 0.016 14.5 0.1 0.024 13.9 0.1 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Glu_syn_central PF04898.14 EST47150.1 - 0.087 12.3 3.3 0.11 11.9 3.3 1.1 1 0 0 1 1 1 0 Glutamate synthase central domain DUF4763 PF15960.5 EST47152.1 - 0.053 12.8 1.1 0.078 12.3 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Arm PF00514.23 EST47153.1 - 6.5e-13 48.2 6.2 0.49 10.5 0.0 9.9 9 1 1 10 10 10 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EST47153.1 - 0.0012 19.1 2.1 1.9 8.9 0.0 4.7 5 0 0 5 5 5 1 HEAT repeats RNase_P_pop3 PF08228.11 EST47153.1 - 0.05 13.6 1.6 3 7.9 0.1 2.5 1 1 1 2 2 2 0 RNase P subunit Pop3 OmpH PF03938.14 EST47153.1 - 0.22 11.9 1.7 1.8 8.9 0.7 2.7 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) SIR2 PF02146.17 EST47154.1 - 6.8e-28 97.8 0.0 9.4e-28 97.3 0.0 1.2 1 0 0 1 1 1 1 Sir2 family Sel1 PF08238.12 EST47154.1 - 0.18 12.5 0.1 0.37 11.5 0.1 1.4 1 0 0 1 1 1 0 Sel1 repeat TPR_1 PF00515.28 EST47155.1 - 1.4e-68 224.1 53.7 1.4e-09 37.4 0.2 14.9 14 1 1 15 15 15 14 Tetratricopeptide repeat TPR_2 PF07719.17 EST47155.1 - 2.7e-62 201.9 46.3 5.9e-07 29.1 0.1 15.1 14 1 1 15 15 15 13 Tetratricopeptide repeat TPR_8 PF13181.6 EST47155.1 - 2.6e-45 148.9 49.4 7.7e-06 25.7 0.1 14.9 14 1 1 15 15 15 10 Tetratricopeptide repeat TPR_11 PF13414.6 EST47155.1 - 1.5e-36 123.8 48.2 2.3e-07 30.4 0.5 13.7 5 3 9 14 14 14 11 TPR repeat TPR_12 PF13424.6 EST47155.1 - 1.1e-29 102.5 37.5 8.5e-05 22.8 0.1 10.6 6 3 4 10 10 10 10 Tetratricopeptide repeat TPR_16 PF13432.6 EST47155.1 - 5.6e-29 100.5 15.9 3.8e-05 24.2 0.0 7.7 7 1 0 7 7 7 6 Tetratricopeptide repeat TPR_9 PF13371.6 EST47155.1 - 8.2e-29 99.6 12.2 4.8e-05 23.4 0.1 9.3 3 3 6 10 10 10 6 Tetratricopeptide repeat TPR_17 PF13431.6 EST47155.1 - 1.9e-25 87.4 42.1 0.0028 17.9 0.0 13.6 14 2 1 15 15 14 6 Tetratricopeptide repeat TPR_19 PF14559.6 EST47155.1 - 2.4e-18 66.4 37.7 0.00087 19.7 0.0 10.0 6 3 3 11 11 11 7 Tetratricopeptide repeat TPR_14 PF13428.6 EST47155.1 - 3.7e-17 61.6 18.6 0.066 14.1 0.4 12.0 5 3 9 14 14 13 4 Tetratricopeptide repeat TPR_7 PF13176.6 EST47155.1 - 1.4e-14 53.0 26.4 0.0039 17.1 0.0 11.5 13 1 0 13 13 12 4 Tetratricopeptide repeat TPR_6 PF13174.6 EST47155.1 - 7.9e-10 38.7 38.6 0.84 10.4 0.1 12.2 15 0 0 15 15 12 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EST47155.1 - 2.9e-08 33.8 39.6 0.12 12.6 0.3 8.2 2 2 6 9 9 9 6 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.7 EST47155.1 - 3.9e-07 30.2 11.2 0.15 12.1 0.7 7.1 3 3 1 5 5 5 2 Domain of Unknown Function (DUF3856) SHNi-TPR PF10516.9 EST47155.1 - 3.8e-06 26.2 18.5 3.6 7.1 0.0 10.0 11 0 0 11 11 11 1 SHNi-TPR Fis1_TPR_C PF14853.6 EST47155.1 - 4.1e-06 26.8 15.2 0.011 15.8 0.1 5.8 6 1 1 7 7 5 2 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 EST47155.1 - 0.0002 21.1 30.4 3.4 7.6 0.0 11.5 13 0 0 13 13 13 2 Tetratricopeptide repeat TPR_20 PF14561.6 EST47155.1 - 0.00043 20.6 18.5 3.6 8.0 0.1 6.3 4 1 2 6 6 6 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 EST47155.1 - 0.024 15.1 10.7 2.2 8.7 0.1 5.0 3 2 2 5 5 5 0 Alkyl sulfatase dimerisation P2_Phage_GpR PF06891.11 EST47155.1 - 0.11 12.6 2.2 3.9 7.6 0.1 2.8 3 0 0 3 3 2 0 P2 phage tail completion protein R (GpR) BTAD PF03704.17 EST47155.1 - 0.35 11.3 10.1 3.3 8.1 0.1 5.4 4 3 3 7 7 6 0 Bacterial transcriptional activator domain MIT PF04212.18 EST47155.1 - 1.1 9.4 35.9 13 5.9 0.0 10.1 11 1 0 11 11 11 0 MIT (microtubule interacting and transport) domain ChAPs PF09295.10 EST47155.1 - 1.3 8.0 7.0 4.2 6.3 0.3 2.9 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_5 PF12688.7 EST47155.1 - 5.7 7.2 7.4 18 5.6 0.1 4.5 6 2 1 7 7 5 0 Tetratrico peptide repeat DUF3081 PF11280.8 EST47156.1 - 0.027 14.3 0.2 0.037 13.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3081) CDC50 PF03381.15 EST47158.1 - 1.4e-22 80.5 1.3 2e-22 80.0 1.3 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family CDC50 PF03381.15 EST47159.1 - 1.8e-27 96.6 1.5 2.5e-27 96.1 1.5 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family CD47 PF04549.14 EST47159.1 - 0.01 16.0 0.8 0.16 12.2 0.0 2.2 2 0 0 2 2 2 0 CD47 transmembrane region Bromodomain PF00439.25 EST47160.1 - 2e-10 40.6 0.7 4.8e-10 39.4 0.5 1.7 2 0 0 2 2 2 1 Bromodomain NCD1 PF04904.13 EST47160.1 - 0.072 13.1 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) RNR_N PF08343.10 EST47160.1 - 0.087 12.9 1.5 2.8 8.0 1.5 2.5 1 1 0 1 1 1 0 Ribonucleotide reductase N-terminal RhoGAP PF00620.27 EST47160.1 - 0.089 12.6 0.2 0.17 11.7 0.2 1.5 1 1 0 1 1 1 0 RhoGAP domain L27_2 PF09045.10 EST47160.1 - 0.11 12.4 0.3 1.1 9.3 0.1 2.5 2 0 0 2 2 2 0 L27_2 Pkinase PF00069.25 EST47162.1 - 4.7e-77 258.9 0.1 7.2e-77 258.3 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST47162.1 - 2e-43 148.6 0.1 2.7e-43 148.1 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EST47162.1 - 5.5e-09 35.8 0.0 9.5e-09 35.0 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EST47162.1 - 1e-05 24.7 0.6 1.5e-05 24.1 0.6 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EST47162.1 - 0.00026 20.4 0.3 0.00051 19.5 0.3 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EST47162.1 - 0.0025 17.8 0.0 0.0042 17.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EST47162.1 - 0.0025 17.5 1.2 0.0039 16.8 0.2 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase RNase_H PF00075.24 EST47163.1 - 1.8 8.8 5.9 1.4 9.1 2.5 2.4 2 0 0 2 2 2 0 RNase H DUF406 PF04175.12 EST47163.1 - 4.7 7.8 7.0 9.2 6.8 0.1 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF406) SNF2_N PF00176.23 EST47164.1 - 3.8e-36 124.5 1.2 6.1e-36 123.8 0.1 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EST47164.1 - 1.4e-15 57.6 0.7 6.2e-15 55.5 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EST47164.1 - 4.5e-08 33.3 0.0 1.8e-07 31.3 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EST47164.1 - 1.2e-05 24.7 0.4 3.5e-05 23.2 0.1 1.9 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase MscS_porin PF12795.7 EST47165.1 - 0.0037 16.9 12.4 0.0037 16.9 12.4 7.0 1 1 2 5 5 5 2 Mechanosensitive ion channel porin domain Cep57_MT_bd PF06657.13 EST47165.1 - 0.016 15.7 7.1 0.016 15.7 7.1 11.5 6 3 5 13 13 13 0 Centrosome microtubule-binding domain of Cep57 ATG16 PF08614.11 EST47165.1 - 4.7 7.4 162.9 0.11 12.7 34.2 7.9 1 1 5 7 7 7 0 Autophagy protein 16 (ATG16) EIIA-man PF03610.16 EST47166.1 - 0.0034 17.6 0.1 0.061 13.6 0.0 2.1 1 1 1 2 2 2 1 PTS system fructose IIA component Fe_hyd_lg_C PF02906.14 EST47167.1 - 5.6e-66 222.7 1.7 7.1e-66 222.3 1.7 1.1 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fer4_7 PF12838.7 EST47167.1 - 2.9e-08 34.2 4.3 2.9e-08 34.2 4.3 2.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_15 PF13459.6 EST47167.1 - 4.6e-07 30.5 2.5 0.012 16.3 0.0 3.1 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_6 PF12837.7 EST47167.1 - 2.1e-06 27.5 16.1 0.00011 22.1 1.0 3.4 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 EST47167.1 - 2.3e-06 27.7 8.4 2.3e-06 27.6 1.5 3.4 3 1 1 4 4 4 2 4Fe-4S dicluster domain Fer4 PF00037.27 EST47167.1 - 2.6e-06 27.0 12.6 9.4e-06 25.2 1.7 3.1 3 1 0 3 3 2 2 4Fe-4S binding domain Fe_hyd_SSU PF02256.17 EST47167.1 - 3.2e-05 23.9 1.3 5.6e-05 23.1 1.3 1.4 1 0 0 1 1 1 1 Iron hydrogenase small subunit Fer4_10 PF13237.6 EST47167.1 - 5e-05 23.3 18.4 0.00015 21.8 9.0 3.6 3 1 1 4 4 4 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 EST47167.1 - 5.6e-05 24.0 8.3 0.0062 17.4 7.3 3.4 2 1 1 3 3 3 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 EST47167.1 - 0.00089 19.3 19.3 0.004 17.3 11.3 3.6 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 EST47167.1 - 0.0021 18.6 6.4 0.0021 18.6 6.4 2.9 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 EST47167.1 - 0.0045 17.0 2.6 0.0045 17.0 2.6 3.4 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_8 PF13183.6 EST47167.1 - 0.0068 16.8 11.5 0.024 15.1 8.1 3.1 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_22 PF17179.4 EST47167.1 - 0.076 13.9 14.9 0.18 12.7 1.5 3.1 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 EST47167.1 - 0.67 10.5 15.2 1.1 9.9 1.7 3.3 4 0 0 4 4 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 EST47167.1 - 1.7 8.9 9.5 0.67 10.2 0.3 3.4 3 0 0 3 3 3 0 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 EST47167.1 - 2.4 8.4 6.8 39 4.6 0.4 4.0 4 0 0 4 4 4 0 c-SKI Smad4 binding domain Caldesmon PF02029.15 EST47168.1 - 0.015 14.1 8.7 0.02 13.7 8.7 1.1 1 0 0 1 1 1 0 Caldesmon DUF3887 PF13026.6 EST47168.1 - 0.25 12.2 6.0 8.6 7.3 1.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3887) Barstar PF01337.18 EST47169.1 - 0.016 15.2 0.0 0.032 14.3 0.0 1.7 1 1 0 1 1 1 0 Barstar (barnase inhibitor) Nuc_rec_co-act PF08815.10 EST47170.1 - 0.013 15.4 0.2 0.025 14.4 0.2 1.4 1 0 0 1 1 1 0 Nuclear receptor coactivator YxiJ PF14176.6 EST47170.1 - 0.034 14.6 0.4 0.044 14.3 0.4 1.2 1 0 0 1 1 1 0 YxiJ-like protein Shugoshin_N PF07558.11 EST47171.1 - 0.026 14.4 0.8 0.077 12.9 0.6 1.9 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DUF3945 PF13101.6 EST47171.1 - 0.059 13.1 0.5 0.21 11.3 0.5 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3945) bZIP_1 PF00170.21 EST47171.1 - 10 6.3 9.7 1.2 9.2 1.7 3.0 3 0 0 3 3 3 0 bZIP transcription factor Exo_endo_phos PF03372.23 EST47172.1 - 1.5e-10 41.0 0.0 4.2e-10 39.5 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HECT PF00632.25 EST47174.1 - 7.1e-73 245.8 7.6 1.3e-72 244.9 7.6 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 EST47174.1 - 2.4e-05 24.5 1.1 8e-05 22.8 1.1 1.8 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Myb_DNA-binding PF00249.31 EST47177.1 - 0.00015 21.9 0.0 0.00025 21.2 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST47177.1 - 0.00016 21.5 0.4 0.00016 21.5 0.4 1.8 2 0 0 2 2 2 1 Myb DNA-binding like BAR_2 PF10455.9 EST47177.1 - 0.0044 16.2 0.6 0.0066 15.6 0.4 1.5 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking YabA PF06156.13 EST47177.1 - 0.023 15.3 0.6 0.064 13.9 0.6 1.8 1 1 0 1 1 1 0 Initiation control protein YabA SLIDE PF09111.10 EST47177.1 - 0.026 14.6 3.2 0.038 14.0 0.6 2.3 1 1 0 2 2 2 0 SLIDE DUF5344 PF17279.2 EST47177.1 - 0.051 14.2 0.1 0.051 14.2 0.1 2.0 2 1 0 2 2 2 0 Family of unknown function (DUF5344) Myb_DNA-bind_4 PF13837.6 EST47177.1 - 0.073 13.5 0.7 1.1 9.7 0.1 2.4 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain NPV_P10 PF05531.12 EST47177.1 - 9.2 6.8 7.6 30 5.1 0.1 3.0 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein CLP1_N PF16573.5 EST47178.1 - 0.13 12.5 1.4 0.31 11.3 1.4 1.7 1 0 0 1 1 1 0 N-terminal beta-sandwich domain of polyadenylation factor SNAPc19 PF15497.6 EST47178.1 - 0.16 12.5 15.9 2.8 8.4 7.6 2.7 2 0 0 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Tox-REase-5 PF15648.6 EST47178.1 - 2 9.0 6.4 0.37 11.3 0.4 2.7 2 1 0 2 2 2 0 Restriction endonuclease fold toxin 5 DUF3215 PF11503.8 EST47179.1 - 0.073 12.9 0.4 0.14 12.0 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3215) CENP-L PF13092.6 EST47179.1 - 0.083 13.1 1.2 0.17 12.1 1.2 1.4 1 0 0 1 1 1 0 Kinetochore complex Sim4 subunit Fta1 WW PF00397.26 EST47181.1 - 5.5e-10 39.2 0.6 1.2e-09 38.1 0.6 1.6 1 0 0 1 1 1 1 WW domain Orn_Arg_deC_N PF02784.16 EST47181.1 - 1.5 8.1 9.3 0.27 10.6 3.7 2.2 1 1 1 2 2 2 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain DUF4407 PF14362.6 EST47181.1 - 2.7 7.3 33.3 1.9 7.8 7.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DRMBL PF07522.14 EST47182.1 - 2.7e-13 50.0 0.5 5.2e-13 49.2 0.5 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 EST47182.1 - 0.00097 18.7 0.0 0.002 17.7 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.12 EST47182.1 - 0.0032 17.4 0.1 0.024 14.6 0.1 2.2 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain Malic_M PF03949.15 EST47182.1 - 0.11 11.8 0.1 0.17 11.1 0.1 1.2 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Lactamase_B PF00753.27 EST47182.1 - 0.33 10.9 2.2 7.5 6.5 3.4 2.0 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily MFS_1 PF07690.16 EST47183.1 - 8e-14 51.3 28.9 8e-14 51.3 28.9 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily eIF3g PF12353.8 EST47185.1 - 0.13 12.6 0.4 0.13 12.6 0.4 4.2 3 2 2 5 5 5 0 Eukaryotic translation initiation factor 3 subunit G Glycogen_syn PF05693.13 EST47186.1 - 6.6e-61 206.7 15.1 1.6e-55 188.9 6.6 2.1 1 1 1 2 2 2 2 Glycogen synthase Glyco_transf_5 PF08323.11 EST47186.1 - 0.00079 19.2 1.3 0.0025 17.6 0.6 2.0 1 1 1 2 2 2 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.6 EST47186.1 - 0.17 12.3 0.0 8.6 6.8 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferases group 1 Gcd10p PF04189.13 EST47187.1 - 1.7e-09 37.3 0.0 1.7e-06 27.4 0.0 2.1 1 1 1 2 2 2 2 Gcd10p family TBD PF12845.7 EST47189.1 - 0.16 11.9 3.1 6 6.8 0.2 3.0 3 0 0 3 3 3 0 TBD domain Ank_2 PF12796.7 EST47190.1 - 3.3e-28 98.1 2.5 3.9e-09 37.0 0.1 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EST47190.1 - 6.5e-15 55.3 3.8 2.2e-05 24.9 0.0 5.9 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EST47190.1 - 1.4e-14 52.7 0.3 0.1 13.2 0.0 6.5 5 1 1 6 6 6 5 Ankyrin repeat Ank PF00023.30 EST47190.1 - 6.2e-14 51.7 0.0 0.063 13.8 0.0 6.4 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 EST47190.1 - 3.2e-12 46.4 0.3 1.7e-05 25.0 0.0 4.9 1 1 4 5 5 5 2 Ankyrin repeats (many copies) IQ PF00612.27 EST47191.1 - 0.0024 17.5 0.6 0.007 16.1 0.6 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF150 PF02576.17 EST47191.1 - 0.45 11.0 3.4 8.2 6.9 0.1 3.1 3 0 0 3 3 3 0 RimP N-terminal domain B277 PF17623.2 EST47191.1 - 2.1 7.3 7.9 3.7 6.5 7.9 1.3 1 0 0 1 1 1 0 Domain of unknown function PHM7_cyt PF14703.6 EST47192.1 - 0.014 15.7 0.5 0.033 14.4 0.3 1.7 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter MlaC PF05494.12 EST47192.1 - 0.025 14.4 0.1 11 5.8 0.0 2.8 2 0 0 2 2 2 0 MlaC protein Sld5 PF05916.11 EST47192.1 - 0.041 14.4 0.1 0.15 12.5 0.1 2.0 2 0 0 2 2 2 0 GINS complex protein zf_C2H2_6 PF18450.1 EST47192.1 - 3.1 7.6 5.4 1.6 8.5 0.5 2.3 2 0 0 2 2 2 0 Zinc Finger domain Yip1 PF04893.17 EST47193.1 - 0.11 12.2 11.3 0.17 11.6 11.3 1.3 1 0 0 1 1 1 0 Yip1 domain TMPIT PF07851.13 EST47195.1 - 0.0034 16.7 1.5 0.0038 16.5 1.5 1.1 1 0 0 1 1 1 1 TMPIT-like protein TIC20 PF16166.5 EST47195.1 - 0.0044 16.8 0.2 0.0047 16.7 0.2 1.0 1 0 0 1 1 1 1 Chloroplast import apparatus Tic20-like TACC_C PF05010.14 EST47195.1 - 0.0065 16.3 5.2 0.0072 16.1 5.2 1.1 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal CENP-F_leu_zip PF10473.9 EST47195.1 - 0.013 15.5 3.6 0.014 15.4 3.6 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cluap1 PF10234.9 EST47195.1 - 0.017 14.5 1.9 0.02 14.3 1.9 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 Sec34 PF04136.15 EST47195.1 - 0.022 14.6 2.7 0.026 14.4 2.7 1.2 1 0 0 1 1 1 0 Sec34-like family DUF1515 PF07439.11 EST47195.1 - 0.033 14.2 0.1 0.034 14.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DUF2207 PF09972.9 EST47195.1 - 0.042 12.6 0.1 0.048 12.4 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CENP-Q PF13094.6 EST47195.1 - 0.049 13.8 0.5 0.055 13.7 0.5 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DASH_Dad3 PF08656.10 EST47195.1 - 0.092 12.8 1.5 0.33 11.1 1.5 2.0 1 1 0 1 1 1 0 DASH complex subunit Dad3 DUF2408 PF10303.9 EST47195.1 - 0.092 13.3 1.3 0.11 13.0 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DUF1664 PF07889.12 EST47195.1 - 0.18 11.8 2.7 0.31 11.1 1.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 EST47195.1 - 0.28 11.5 0.1 0.28 11.5 0.1 2.1 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) SLATT_fungal PF18142.1 EST47195.1 - 5.4 7.0 6.0 1.4 8.9 1.3 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain DUF4891 PF16232.5 EST47197.1 - 0.033 14.7 0.1 0.098 13.2 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4891) Mucin-like PF16058.5 EST47199.1 - 0.29 11.3 29.1 0.61 10.2 9.2 3.3 1 1 2 3 3 3 0 Mucin-like Pkinase PF00069.25 EST47200.1 - 1.5e-24 86.8 0.2 1.5e-24 86.8 0.2 1.9 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST47200.1 - 2.6e-10 40.0 0.0 5.8e-10 38.9 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EST47200.1 - 2.2e-06 27.2 0.0 3.5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 EST47200.1 - 0.016 14.9 0.5 0.042 13.5 0.0 2.0 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EST47200.1 - 0.063 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NIF PF03031.18 EST47201.1 - 3.6e-34 117.8 0.3 3.6e-34 117.8 0.3 1.5 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase WD40 PF00400.32 EST47202.1 - 0.0013 19.5 2.1 15 6.6 0.0 5.6 5 0 0 5 5 5 2 WD domain, G-beta repeat zf-B_box PF00643.24 EST47203.1 - 8.7e-05 22.6 16.7 0.0048 17.0 0.9 2.9 3 0 0 3 3 3 2 B-box zinc finger RecR PF02132.15 EST47203.1 - 3.1 7.4 5.8 0.74 9.4 0.4 2.5 2 0 0 2 2 2 0 RecR protein DUF1514 PF07438.11 EST47204.1 - 0.3 11.0 6.1 13 5.8 0.1 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1514) YtxH PF12732.7 EST47205.1 - 0.014 15.9 2.5 0.5 10.9 0.7 3.0 2 0 0 2 2 2 0 YtxH-like protein Syntaxin-6_N PF09177.11 EST47205.1 - 0.014 15.9 5.0 0.096 13.2 0.8 2.7 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Seryl_tRNA_N PF02403.22 EST47205.1 - 0.11 12.8 10.5 1.3 9.3 0.8 3.4 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain PrkA PF06798.12 EST47205.1 - 0.18 11.4 4.4 0.24 11.0 0.2 2.4 2 0 0 2 2 2 0 PrkA serine protein kinase C-terminal domain DUF2408 PF10303.9 EST47205.1 - 0.8 10.3 13.4 0.093 13.3 3.2 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF2408) TFIIE_alpha PF02002.17 EST47205.1 - 0.95 9.4 6.2 0.2 11.5 0.3 2.8 3 0 0 3 3 3 0 TFIIE alpha subunit P4Ha_N PF08336.11 EST47205.1 - 4.5 7.3 10.3 0.85 9.6 1.8 2.8 3 0 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region ARA70 PF12489.8 EST47205.1 - 6.9 6.9 8.3 0.39 10.9 0.8 2.6 3 0 0 3 3 3 0 Nuclear coactivator Sds3 PF08598.11 EST47206.1 - 0.00017 21.6 4.9 0.00023 21.3 4.9 1.1 1 0 0 1 1 1 1 Sds3-like DUF1841 PF08897.11 EST47206.1 - 0.034 14.2 0.3 0.057 13.4 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1841) FadA PF09403.10 EST47206.1 - 0.079 13.5 6.0 0.1 13.1 6.0 1.2 1 0 0 1 1 1 0 Adhesion protein FadA HEAT PF02985.22 EST47207.1 - 8.2e-12 44.3 5.8 2.4 8.6 0.0 9.9 10 0 0 10 10 10 4 HEAT repeat HEAT_2 PF13646.6 EST47207.1 - 1.6e-09 38.0 0.7 0.0052 17.1 0.0 5.6 3 1 2 5 5 5 3 HEAT repeats Vac14_Fab1_bd PF12755.7 EST47207.1 - 6.7e-05 23.4 15.3 1.3 9.6 1.8 5.9 3 2 2 6 6 6 4 Vacuolar 14 Fab1-binding region EcsC PF12787.7 EST47207.1 - 0.1 12.3 2.5 0.29 10.8 0.3 2.6 3 0 0 3 3 3 0 EcsC protein family Ssl1 PF04056.14 EST47208.1 - 8.5e-12 45.3 2.6 1.2e-11 44.8 2.6 1.2 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.28 EST47208.1 - 5.2e-06 26.8 0.9 7.3e-06 26.3 0.9 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EST47208.1 - 1.6e-05 25.5 1.0 5.6e-05 23.8 0.1 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain 5_3_exonuc_N PF02739.16 EST47210.1 - 0.021 14.8 0.3 0.052 13.5 0.3 1.6 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain DEAD PF00270.29 EST47211.1 - 1.4e-43 148.7 4.5 1.4e-43 148.7 4.5 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EST47211.1 - 6.5e-30 103.7 2.7 1.3e-28 99.5 0.2 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EST47211.1 - 3.9e-09 36.7 0.5 8.7e-09 35.6 0.1 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EST47211.1 - 6e-08 32.6 0.6 9.6e-08 32.0 0.6 1.3 1 0 0 1 1 1 1 AAA domain CMS1 PF14617.6 EST47211.1 - 1.2e-05 24.8 1.0 3e-05 23.5 0.1 2.0 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.6 EST47211.1 - 0.00045 20.6 1.3 0.00045 20.6 1.3 1.8 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EST47211.1 - 0.0019 18.5 0.3 0.0043 17.3 0.3 1.6 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 EST47211.1 - 0.0027 17.6 0.7 0.0052 16.7 0.1 1.8 2 1 0 2 2 2 1 Helicase Flavi_DEAD PF07652.14 EST47211.1 - 0.0057 16.6 1.6 0.14 12.1 0.2 2.9 2 1 0 2 2 2 1 Flavivirus DEAD domain ERCC3_RAD25_C PF16203.5 EST47211.1 - 0.037 13.3 0.1 0.058 12.6 0.1 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Vip3A_N PF12495.8 EST47211.1 - 0.12 12.2 4.7 0.046 13.6 1.1 2.0 1 1 1 2 2 2 0 Vegetative insecticide protein 3A N terminal NAGidase PF07555.13 EST47211.1 - 0.23 10.7 1.2 5.3 6.3 0.1 2.1 2 0 0 2 2 2 0 beta-N-acetylglucosaminidase Peptidase_M61 PF05299.12 EST47212.1 - 0.34 11.3 6.1 0.076 13.4 1.8 2.2 2 0 0 2 2 2 0 M61 glycyl aminopeptidase DUF2716 PF10898.8 EST47212.1 - 5.9 7.3 7.9 2.2 8.6 1.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2716) ParB PF08775.10 EST47213.1 - 0.011 16.2 12.0 0.059 13.8 6.8 2.5 1 1 1 2 2 2 0 ParB family CFTR_R PF14396.6 EST47213.1 - 0.095 12.2 3.6 0.12 11.9 3.6 1.2 1 0 0 1 1 1 0 Cystic fibrosis TM conductance regulator (CFTR), regulator domain Snf7 PF03357.21 EST47213.1 - 0.31 10.6 16.9 0.47 10.0 16.9 1.4 1 1 0 1 1 1 0 Snf7 DUF4572 PF15139.6 EST47214.1 - 0.023 14.6 0.1 0.054 13.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4572) Ran_BP1 PF00638.18 EST47215.1 - 2.8e-15 56.6 0.7 4.9e-15 55.9 0.1 1.6 1 1 1 2 2 2 1 RanBP1 domain Arc_PepC_II PF06847.11 EST47215.1 - 0.078 13.5 0.6 0.15 12.6 0.6 1.5 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminus Type II Ras PF00071.22 EST47216.1 - 2.9e-21 75.7 2.8 3.1e-21 75.7 0.4 2.3 2 0 0 2 2 2 1 Ras family Roc PF08477.13 EST47216.1 - 9.9e-14 51.6 0.8 8.8e-13 48.5 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EST47216.1 - 1.2e-05 24.8 0.0 3.3e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 ADP-ribosylation factor family CH PF00307.31 EST47216.1 - 0.0004 20.5 2.4 0.00086 19.5 0.3 2.5 2 0 0 2 2 2 1 Calponin homology (CH) domain GTP_EFTU PF00009.27 EST47216.1 - 0.00042 19.9 0.2 0.0094 15.5 0.0 3.0 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EST47216.1 - 0.0012 18.9 1.2 0.0039 17.3 0.0 2.5 3 1 0 3 3 3 1 50S ribosome-binding GTPase RAMPs PF03787.15 EST47216.1 - 0.34 10.9 1.6 1 9.4 1.6 2.0 1 1 0 1 1 1 0 RAMP superfamily Ribosomal_60s PF00428.19 EST47217.1 - 3.8e-06 27.4 0.0 1.1e-05 25.9 0.0 1.8 1 0 0 1 1 1 1 60s Acidic ribosomal protein CH PF00307.31 EST47217.1 - 0.056 13.6 0.4 0.19 11.9 0.4 1.8 1 0 0 1 1 1 0 Calponin homology (CH) domain YkuD_2 PF13645.6 EST47218.1 - 0.003 17.0 1.6 0.0054 16.2 1.6 1.4 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain ZapB PF06005.12 EST47218.1 - 0.0089 16.5 29.8 0.013 16.0 4.4 3.1 2 1 1 3 3 3 2 Cell division protein ZapB NRBF2 PF08961.10 EST47218.1 - 0.015 14.9 3.2 0.015 14.9 3.2 2.1 1 1 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator DUF1664 PF07889.12 EST47218.1 - 0.077 13.0 16.2 0.39 10.8 3.5 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) YabA PF06156.13 EST47218.1 - 0.091 13.4 23.0 0.22 12.2 7.1 2.8 1 1 1 3 3 3 0 Initiation control protein YabA KASH_CCD PF14662.6 EST47218.1 - 0.12 12.2 26.8 0.31 10.8 6.2 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH bZIP_1 PF00170.21 EST47218.1 - 1.8 8.7 17.0 1.3 9.1 4.4 3.2 2 2 0 2 2 2 0 bZIP transcription factor APG6_N PF17675.1 EST47218.1 - 2.4 8.7 25.9 2.5 8.7 2.6 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region FAST_2 PF08368.12 EST47218.1 - 4 8.3 8.2 0.96 10.3 3.0 2.4 1 1 1 2 2 2 0 FAST kinase-like protein, subdomain 2 CENP-F_leu_zip PF10473.9 EST47218.1 - 6.8 6.7 25.8 19 5.3 7.7 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMPIT PF07851.13 EST47218.1 - 8 5.6 22.8 1.7 7.8 3.7 2.1 2 0 0 2 2 2 0 TMPIT-like protein PDEase_I PF00233.19 EST47221.1 - 7.1e-09 35.7 2.2 7.1e-09 35.7 2.2 2.9 3 1 0 3 3 3 1 3'5'-cyclic nucleotide phosphodiesterase Gluconate_2-dh3 PF13618.6 EST47221.1 - 0.086 13.1 1.8 6.6 7.0 0.0 2.8 2 0 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 DUF1972 PF09314.11 EST47222.1 - 0.12 11.9 0.1 0.13 11.8 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1972) Motile_Sperm PF00635.26 EST47224.1 - 0.00097 19.0 0.3 0.009 15.8 0.1 2.8 2 0 0 2 2 2 1 MSP (Major sperm protein) domain Y_Y_Y PF07495.13 EST47224.1 - 0.0064 16.4 0.1 0.03 14.3 0.1 2.2 1 0 0 1 1 1 1 Y_Y_Y domain DUF5426 PF17473.2 EST47224.1 - 0.055 13.7 1.1 0.22 11.8 1.1 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5426) Ndc80_HEC PF03801.13 EST47225.1 - 0.022 14.4 0.2 0.025 14.2 0.2 1.2 1 0 0 1 1 1 0 HEC/Ndc80p family Lzipper-MIP1 PF14389.6 EST47225.1 - 0.031 14.6 2.2 0.045 14.1 2.2 1.3 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Peptidase_S46 PF10459.9 EST47227.1 - 0.024 13.3 1.3 0.027 13.1 1.3 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF1793 PF08760.11 EST47227.1 - 0.056 13.9 0.0 0.089 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1793) Ribosomal_L37ae PF01780.19 EST47229.1 - 2.2e-35 120.6 8.7 2.5e-35 120.4 8.7 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Lar_restr_allev PF14354.6 EST47229.1 - 0.0041 17.5 0.7 0.0061 16.9 0.7 1.4 1 0 0 1 1 1 1 Restriction alleviation protein Lar zf-H2C2_2 PF13465.6 EST47229.1 - 0.01 16.2 1.3 0.44 11.1 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double domain Rep_fac-A_C PF08646.10 EST47229.1 - 0.016 14.9 1.2 0.02 14.6 1.2 1.2 1 0 0 1 1 1 0 Replication factor-A C terminal domain zf-RING_13 PF17977.1 EST47229.1 - 0.026 14.6 2.5 0.037 14.2 2.5 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 EST47229.1 - 0.028 14.4 4.1 0.046 13.7 4.1 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Sgf11 PF08209.11 EST47229.1 - 0.1 12.2 2.1 2.2 7.9 0.1 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Elf1 PF05129.13 EST47229.1 - 0.15 12.1 4.1 0.26 11.4 4.1 1.4 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like Ank_2 PF12796.7 EST47231.1 - 0.0007 20.1 0.0 0.0025 18.4 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EST47231.1 - 0.0019 18.7 0.0 0.0069 16.9 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EST47231.1 - 0.046 14.3 0.2 29 5.7 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeat Ank PF00023.30 EST47231.1 - 0.098 13.1 0.1 1.6 9.3 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat Annexin PF00191.20 EST47233.1 - 2.5e-10 40.3 7.3 0.00011 22.2 0.1 3.4 3 0 0 3 3 3 3 Annexin Actin PF00022.19 EST47235.1 - 1.8e-10 40.0 0.0 1.5e-08 33.7 0.0 2.4 3 0 0 3 3 3 2 Actin Pro_racemase PF05544.11 EST47236.1 - 0.12 11.5 0.7 0.15 11.1 0.7 1.1 1 0 0 1 1 1 0 Proline racemase Zn_ribbon_2 PF12674.7 EST47237.1 - 0.059 14.0 1.0 0.22 12.2 0.4 2.2 2 0 0 2 2 2 0 Putative zinc ribbon domain Synaptobrevin PF00957.21 EST47239.1 - 1.8e-13 50.1 0.9 1.9e-13 50.0 0.9 1.0 1 0 0 1 1 1 1 Synaptobrevin KELK PF15796.5 EST47239.1 - 0.11 13.0 2.3 0.49 10.9 0.3 1.9 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Dioxygenase_N PF04444.14 EST47240.1 - 0.022 14.6 0.1 0.095 12.6 0.1 2.0 2 0 0 2 2 2 0 Catechol dioxygenase N terminus SMC_N PF02463.19 EST47241.1 - 6.3e-50 169.6 55.9 2.8e-46 157.7 55.9 5.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EST47241.1 - 7.3e-19 68.2 0.0 5.5e-18 65.4 0.0 2.7 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EST47241.1 - 2.4e-11 44.0 19.0 2.9e-06 27.3 0.0 4.6 5 1 0 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EST47241.1 - 4.5e-07 29.5 0.0 1.4e-06 28.0 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EST47241.1 - 1.3e-05 25.8 32.7 1.3e-05 25.8 32.7 8.4 2 2 5 7 7 7 1 AAA domain HAUS-augmin3 PF14932.6 EST47242.1 - 0.0094 15.6 7.3 0.0094 15.6 7.3 2.1 1 1 1 2 2 2 1 HAUS augmin-like complex subunit 3 YabA PF06156.13 EST47242.1 - 0.013 16.1 2.8 0.013 16.1 2.8 2.8 1 1 1 2 2 1 0 Initiation control protein YabA ZapB PF06005.12 EST47242.1 - 0.014 15.8 2.2 0.014 15.8 2.2 3.3 1 1 1 2 2 1 0 Cell division protein ZapB APG6_N PF17675.1 EST47242.1 - 0.015 15.8 17.0 0.015 15.8 17.0 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Lebercilin PF15619.6 EST47242.1 - 0.03 14.0 30.7 1.3 8.6 30.7 2.1 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Seryl_tRNA_N PF02403.22 EST47242.1 - 0.059 13.6 26.5 0.29 11.4 12.6 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4795 PF16043.5 EST47242.1 - 0.13 11.8 26.8 1.3 8.6 26.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) NPV_P10 PF05531.12 EST47242.1 - 0.15 12.6 8.0 1.7 9.2 0.1 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TPR_MLP1_2 PF07926.12 EST47242.1 - 0.18 11.9 26.9 0.26 11.3 9.3 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein MIP-T3_C PF17749.1 EST47242.1 - 0.21 11.5 23.7 0.3 11.1 5.7 2.0 1 1 1 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region ATG16 PF08614.11 EST47242.1 - 0.26 11.5 27.6 0.56 10.4 4.8 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) HMMR_N PF15905.5 EST47242.1 - 0.38 10.2 30.3 0.53 9.7 23.9 2.0 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal MAD PF05557.13 EST47242.1 - 0.46 8.8 29.6 0.82 8.0 29.0 1.6 1 1 0 1 1 1 0 Mitotic checkpoint protein Bap31_Bap29_C PF18035.1 EST47242.1 - 0.54 10.3 0.1 0.54 10.3 0.1 3.6 3 1 0 3 3 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Hemagglutinin PF00509.18 EST47242.1 - 0.61 8.4 8.5 0.068 11.6 4.1 1.6 1 1 1 2 2 2 0 Haemagglutinin DUF724 PF05266.14 EST47242.1 - 0.63 9.8 25.8 0.16 11.8 10.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) AAA_13 PF13166.6 EST47242.1 - 0.8 8.3 22.9 8.7 4.8 22.2 1.7 1 1 0 1 1 1 0 AAA domain ERM PF00769.19 EST47242.1 - 0.84 9.4 28.9 0.84 9.4 15.1 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family UPF0449 PF15136.6 EST47242.1 - 0.91 10.0 23.6 0.54 10.8 4.0 2.9 2 1 1 3 3 3 0 Uncharacterised protein family UPF0449 HIP1_clath_bdg PF16515.5 EST47242.1 - 1 10.0 29.9 0.28 11.8 14.0 2.5 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DASH_Dam1 PF08653.10 EST47242.1 - 1.3 8.8 6.1 13 5.7 0.1 3.0 2 1 1 3 3 3 0 DASH complex subunit Dam1 DUF4200 PF13863.6 EST47242.1 - 1.3 9.4 34.1 16 5.9 15.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) zf-C4H2 PF10146.9 EST47242.1 - 1.6 9.0 18.2 0.48 10.7 14.8 1.8 1 1 0 1 1 1 0 Zinc finger-containing protein Tli4_N PF18443.1 EST47242.1 - 1.7 9.0 12.0 1.7 9.0 8.9 2.1 1 1 1 2 2 2 0 Tle cognate immunity protein 4 N-terminal domain DUF1664 PF07889.12 EST47242.1 - 2.1 8.4 19.2 0.85 9.7 4.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 EST47242.1 - 2.2 7.1 28.5 0.24 10.2 21.7 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein BLOC1_2 PF10046.9 EST47242.1 - 2.8 8.3 24.1 1.2 9.5 2.1 3.1 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc24 PF08286.11 EST47242.1 - 3.2 8.0 23.5 14 6.0 1.3 3.3 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 OmpH PF03938.14 EST47242.1 - 5.5 7.3 34.4 3 8.2 27.2 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF948 PF06103.11 EST47242.1 - 5.6 7.3 10.1 17 5.7 1.5 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) FliD_N PF02465.18 EST47242.1 - 6 7.6 19.6 4.3 8.1 5.1 2.4 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus RSN1_7TM PF02714.15 EST47245.1 - 1.7e-19 70.2 29.1 1.7e-19 70.2 29.1 2.8 2 1 1 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EST47245.1 - 8.8e-08 32.1 11.0 8.8e-08 32.1 11.0 4.4 4 2 1 5 5 5 1 Late exocytosis, associated with Golgi transport Gar1 PF04410.14 EST47246.1 - 0.0013 18.6 0.1 0.0019 18.0 0.1 1.3 1 1 0 1 1 1 1 Gar1/Naf1 RNA binding region PulA_N1 PF17999.1 EST47246.1 - 0.086 13.6 0.1 0.3 11.9 0.0 2.0 1 1 1 2 2 2 0 Pullulanase N1-terminal domain DEAD PF00270.29 EST47247.1 - 2.2e-31 109.0 0.1 3.9e-31 108.2 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EST47247.1 - 9.1e-22 77.5 0.2 2.8e-21 75.9 0.2 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EST47247.1 - 1.4e-05 25.1 0.0 3.3e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Kinesin PF00225.23 EST47248.1 - 2.3e-93 312.7 1.0 2.3e-93 312.7 1.0 2.1 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EST47248.1 - 1.4e-21 77.0 0.7 1.4e-21 77.0 0.7 2.5 2 1 1 3 3 3 1 Microtubule binding H_lectin PF09458.10 EST47248.1 - 0.13 12.5 0.7 0.6 10.3 0.4 2.4 2 0 0 2 2 2 0 H-type lectin domain WD40_like PF17005.5 EST47251.1 - 0.14 11.5 7.8 0.16 11.2 6.2 1.8 1 1 1 2 2 2 0 WD40-like domain Peptidase_M50 PF02163.22 EST47251.1 - 0.31 10.3 1.6 0.53 9.5 1.6 1.3 1 0 0 1 1 1 0 Peptidase family M50 Prefoldin PF02996.17 EST47253.1 - 6.9e-17 61.5 0.3 1.1e-16 60.9 0.3 1.4 1 1 0 1 1 1 1 Prefoldin subunit SesA PF17107.5 EST47253.1 - 0.022 14.9 0.6 0.037 14.2 0.2 1.5 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Branch PF02485.21 EST47253.1 - 0.092 12.2 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Core-2/I-Branching enzyme MreB_Mbl PF06723.13 EST47253.1 - 0.097 11.5 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 MreB/Mbl protein CK_II_beta PF01214.18 EST47256.1 - 9.9e-35 120.0 1.5 1.2e-34 119.7 1.5 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Rep_fac-A_C PF08646.10 EST47256.1 - 0.083 12.6 0.6 0.17 11.6 0.6 1.5 1 0 0 1 1 1 0 Replication factor-A C terminal domain Pkinase PF00069.25 EST47257.1 - 1.2e-71 241.1 0.1 1.5e-71 240.8 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST47257.1 - 4.6e-37 127.7 0.1 6.8e-37 127.1 0.1 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EST47257.1 - 3.6e-07 29.8 0.0 1e-06 28.3 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EST47257.1 - 2.1e-05 23.6 0.3 4e-05 22.7 0.3 1.4 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 EST47257.1 - 0.0097 15.6 0.2 0.15 11.7 0.1 2.3 1 1 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EST47257.1 - 0.02 14.8 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EST47257.1 - 0.028 13.2 0.0 0.046 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 EST47257.1 - 0.031 13.9 0.1 0.05 13.2 0.1 1.4 1 0 0 1 1 1 0 RIO1 family WD40 PF00400.32 EST47258.1 - 4.2e-06 27.4 0.9 0.32 11.9 0.0 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EST47258.1 - 1.9e-05 24.9 0.0 0.2 12.0 0.0 4.0 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain SepSecS PF05889.13 EST47259.1 - 6.7e-85 285.1 0.2 8.7e-85 284.7 0.2 1.1 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS LicD PF04991.13 EST47262.1 - 0.22 11.6 12.3 0.25 11.4 12.3 1.2 1 0 0 1 1 1 0 LicD family SlyX PF04102.12 EST47262.1 - 4.4 8.0 11.2 0.6 10.8 3.9 2.6 1 1 1 2 2 2 0 SlyX MFS_1 PF07690.16 EST47263.1 - 3.3e-35 121.7 44.5 3.3e-35 121.7 44.5 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.13 EST47263.1 - 5e-07 28.5 1.6 5e-07 28.5 1.6 1.5 2 0 0 2 2 2 1 Transmembrane secretion effector Toprim_2 PF13155.6 EST47264.1 - 0.14 12.6 0.1 5 7.6 0.0 2.3 2 0 0 2 2 2 0 Toprim-like SHIPPO-rpt PF07004.12 EST47265.1 - 1.4e-23 82.7 30.1 6.5e-05 23.7 3.3 6.2 6 0 0 6 6 6 6 Sperm-tail PG-rich repeat ECR1_N PF14382.6 EST47265.1 - 0.12 12.2 0.0 10 6.0 0.0 3.4 4 0 0 4 4 4 0 Exosome complex exonuclease RRP4 N-terminal region SHIPPO-rpt PF07004.12 EST47266.1 - 1.1e-31 108.3 27.8 6.4e-06 26.8 0.6 6.2 6 0 0 6 6 6 6 Sperm-tail PG-rich repeat DUF4718 PF15842.5 EST47268.1 - 0.14 11.9 1.8 0.16 11.8 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) ABC_tran PF00005.27 EST47269.1 - 2.1e-37 128.7 0.0 6.2e-18 65.6 0.0 3.5 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EST47269.1 - 1.3e-28 100.4 62.1 2.1e-21 76.8 27.6 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EST47269.1 - 1.1e-09 38.0 0.0 0.00086 18.8 0.0 2.5 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EST47269.1 - 8.2e-05 22.6 0.3 0.85 9.4 0.0 4.5 4 1 0 5 5 5 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EST47269.1 - 0.00062 19.7 0.1 0.01 15.7 0.0 2.8 3 0 0 3 3 3 1 RsgA GTPase MMR_HSR1 PF01926.23 EST47269.1 - 0.0019 18.3 0.0 0.088 12.9 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_7 PF12775.7 EST47269.1 - 0.0097 15.4 1.4 0.64 9.5 0.0 3.5 4 0 0 4 4 4 1 P-loop containing dynein motor region MeaB PF03308.16 EST47269.1 - 0.025 13.6 0.0 0.53 9.2 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PRK PF00485.18 EST47269.1 - 0.028 14.2 0.0 0.21 11.3 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 EST47269.1 - 0.042 14.0 0.0 0.28 11.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EST47269.1 - 0.043 13.9 0.7 18 5.3 0.0 3.0 2 1 0 2 2 2 0 Helicase HerA, central domain TsaE PF02367.17 EST47269.1 - 0.049 13.6 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 EST47269.1 - 0.049 13.5 0.3 0.74 9.7 0.0 2.9 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_22 PF13401.6 EST47269.1 - 0.088 13.1 0.0 0.55 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EST47269.1 - 0.096 12.4 0.4 2.5 7.9 0.2 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain cobW PF02492.19 EST47269.1 - 0.11 12.1 0.0 0.28 10.7 0.0 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain bZIP_1 PF00170.21 EST47270.1 - 0.017 15.2 3.4 0.017 15.2 3.4 6.7 3 1 2 6 6 6 0 bZIP transcription factor Antimicrobial18 PF08130.11 EST47270.1 - 1.9 8.6 6.2 20 5.4 0.3 3.1 1 1 1 2 2 2 0 Type A lantibiotic family Ribosomal_S7 PF00177.21 EST47271.1 - 3.2e-30 104.8 1.1 3.8e-30 104.5 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Pkinase PF00069.25 EST47273.1 - 1.2e-29 103.5 0.2 1.5e-29 103.2 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST47273.1 - 9.5e-16 57.8 0.0 1.5e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EST47273.1 - 0.00024 20.2 0.4 0.00024 20.2 0.4 2.4 2 1 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 EST47273.1 - 0.019 14.9 0.0 0.066 13.1 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 EST47274.1 - 2.5e-49 168.0 8.4 3.5e-35 121.7 4.9 3.0 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EST47274.1 - 1.3e-21 77.1 2.9 3.6e-20 72.3 1.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase POLO_box PF00659.18 EST47274.1 - 1.3e-08 34.8 2.5 0.00013 22.1 0.2 3.1 3 0 0 3 3 3 2 POLO box duplicated region APH PF01636.23 EST47274.1 - 0.0076 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EST47274.1 - 0.0096 15.3 3.7 0.13 11.6 0.0 2.9 2 1 0 3 3 3 1 Kinase-like YscJ_FliF_C PF08345.11 EST47275.1 - 0.022 15.1 3.1 0.026 14.9 3.1 1.1 1 0 0 1 1 1 0 Flagellar M-ring protein C-terminal HABP4_PAI-RBP1 PF04774.15 EST47275.1 - 0.41 11.5 12.5 0.91 10.4 12.5 1.7 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family ORC_WH_C PF18137.1 EST47275.1 - 0.55 10.3 5.2 0.11 12.6 1.8 1.6 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal PS_Dcarbxylase PF02666.15 EST47276.1 - 5.5e-38 130.5 0.8 6.4e-38 130.3 0.8 1.0 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase EF-hand_7 PF13499.6 EST47277.1 - 1.6e-18 66.9 2.4 3.8e-09 36.9 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EST47277.1 - 1.7e-17 61.6 8.8 1.2e-05 24.5 0.0 5.0 4 1 1 5 5 5 4 EF hand EF-hand_8 PF13833.6 EST47277.1 - 1.3e-15 56.9 9.5 1.2e-09 37.8 1.7 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EST47277.1 - 1.9e-14 52.3 5.2 0.00012 21.8 0.0 4.7 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 EST47277.1 - 2.9e-07 29.7 11.5 1.8e-05 24.0 0.0 5.0 5 0 0 5 5 5 1 EF hand EF-hand_4 PF12763.7 EST47277.1 - 0.00089 19.2 6.0 0.045 13.7 0.2 2.8 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EST47277.1 - 0.0025 18.1 0.6 0.24 11.7 0.0 2.1 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 EST47277.1 - 0.021 14.7 1.4 3.6 7.5 0.0 3.1 3 1 1 4 4 4 0 EF hand TAFH PF07531.14 EST47277.1 - 0.097 12.8 0.0 2.1 8.5 0.0 2.1 2 0 0 2 2 2 0 NHR1 homology to TAF DUF1456 PF07308.13 EST47277.1 - 0.12 12.7 0.6 0.42 11.0 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) DUF5517 PF17639.2 EST47278.1 - 0.087 13.1 2.9 0.27 11.5 2.9 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5517) ZapC PF07126.12 EST47279.1 - 0.082 12.5 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Cell-division protein ZapC SLC35F PF06027.12 EST47280.1 - 4.8e-06 26.3 13.2 9.5e-06 25.3 13.2 1.6 1 1 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 EST47280.1 - 0.00063 19.9 31.0 0.0071 16.5 13.0 3.1 2 2 0 2 2 2 2 EamA-like transporter family Neurensin PF14927.6 EST47280.1 - 1.2 8.8 4.5 19 5.0 0.0 3.4 3 1 1 4 4 4 0 Neurensin DUF218 PF02698.17 EST47288.1 - 0.033 14.2 0.1 0.037 14.1 0.1 1.2 1 0 0 1 1 1 0 DUF218 domain Dickkopf_N PF04706.12 EST47289.1 - 0.039 14.4 12.9 0.039 14.4 12.9 5.8 5 3 1 6 6 6 0 Dickkopf N-terminal cysteine-rich region DUF4366 PF14283.6 EST47289.1 - 0.086 12.9 0.1 0.086 12.9 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) CLCA PF08434.11 EST47291.1 - 0.08 12.3 0.1 0.089 12.1 0.1 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel N terminal SYCP2_ARLD PF18581.1 EST47291.1 - 0.26 11.3 3.9 0.25 11.3 3.0 1.5 1 1 1 2 2 2 0 Synaptonemal complex 2 armadillo-repeat-like domain Radical_SAM PF04055.21 EST47294.1 - 9.5e-20 71.6 0.0 1.8e-19 70.7 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 EST47294.1 - 4.6e-14 52.3 0.1 2e-13 50.2 0.1 2.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 FmrO PF07091.11 EST47294.1 - 0.067 12.7 0.1 0.5 9.9 0.0 2.3 3 0 0 3 3 3 0 Ribosomal RNA methyltransferase (FmrO) Phage_int_SAM_3 PF14659.6 EST47295.1 - 0.043 14.1 1.2 0.065 13.5 0.1 1.9 2 1 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Med26_C PF15693.5 EST47295.1 - 0.054 13.6 0.5 0.06 13.5 0.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 26 C-terminal Peptidase_C24 PF03510.14 EST47295.1 - 0.13 12.7 0.0 0.17 12.4 0.0 1.3 1 0 0 1 1 1 0 2C endopeptidase (C24) cysteine protease family SANT_DAMP1_like PF16282.5 EST47296.1 - 0.0007 19.7 0.2 0.00098 19.3 0.2 1.2 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-binding PF00249.31 EST47296.1 - 0.00072 19.7 0.1 0.0018 18.4 0.0 1.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST47296.1 - 0.0013 18.6 0.2 0.0014 18.4 0.2 1.2 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 EST47296.1 - 0.0077 16.5 0.0 0.013 15.7 0.0 1.4 1 1 0 1 1 1 1 Myb-like DNA-binding domain DUF4752 PF15944.5 EST47296.1 - 0.081 13.0 0.1 0.098 12.7 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4752) DUF5318 PF17249.2 EST47296.1 - 0.091 12.5 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5318) DUF4366 PF14283.6 EST47298.1 - 0.049 13.7 0.1 0.068 13.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) VSP PF03302.13 EST47298.1 - 0.053 12.4 32.2 0.2 10.4 32.2 2.2 1 1 0 1 1 1 0 Giardia variant-specific surface protein Mitovir_RNA_pol PF05919.11 EST47303.1 - 0.15 11.2 3.1 0.2 10.8 3.1 1.1 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase Gp58 PF07902.11 EST47303.1 - 2.5 6.3 15.0 1.3 7.3 12.9 1.5 1 1 0 1 1 1 0 gp58-like protein Ras_bdg_2 PF14847.6 EST47305.1 - 0.01 16.1 0.5 0.016 15.6 0.5 1.4 1 0 0 1 1 1 0 Ras-binding domain of Byr2 Allantoicase PF03561.15 EST47305.1 - 0.043 13.8 0.7 0.067 13.2 0.5 1.3 1 1 0 1 1 1 0 Allantoicase repeat CLIP PF12032.8 EST47305.1 - 0.092 13.0 0.5 0.19 12.1 0.5 1.8 1 1 0 1 1 1 0 Regulatory CLIP domain of proteinases Ly-6_related PF06579.12 EST47305.1 - 0.1 12.9 0.6 0.15 12.3 0.4 1.4 1 1 0 1 1 1 0 Caenorhabditis elegans ly-6-related protein MCPVI PF02993.14 EST47306.1 - 0.064 13.1 0.3 0.11 12.3 0.3 1.4 1 0 0 1 1 1 0 Minor capsid protein VI TPR_19 PF14559.6 EST47307.1 - 0.0039 17.7 0.1 0.59 10.7 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Fungal_TACC PF12709.7 EST47307.1 - 0.0093 16.4 3.5 0.13 12.7 2.0 2.6 2 0 0 2 2 2 1 Fungal Transforming acidic coiled-coil (TACC) proteins FLYWCH_u PF16662.5 EST47308.1 - 0.072 13.2 0.5 0.11 12.6 0.1 1.5 2 0 0 2 2 2 0 FLYWCH-type zinc finger-containing protein 1 GH-E PF14410.6 EST47309.1 - 0.029 14.7 0.0 0.057 13.8 0.0 1.4 1 0 0 1 1 1 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues DUF4748 PF15932.5 EST47309.1 - 0.063 13.0 0.2 0.2 11.4 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) SNF2_N PF00176.23 EST47311.1 - 2.8e-28 98.6 0.1 6.9e-28 97.4 0.1 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EST47311.1 - 1.3e-14 54.4 0.4 6.1e-13 49.1 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EST47311.1 - 3.1e-14 53.4 0.4 3.1e-14 53.4 0.4 2.9 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EST47311.1 - 0.0025 17.6 0.1 0.0087 15.8 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase RuvB_N PF05496.12 EST47311.1 - 0.027 14.2 0.0 0.089 12.5 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 EST47311.1 - 0.041 14.2 1.1 6 7.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain FKS1_dom1 PF14288.6 EST47311.1 - 0.061 13.7 1.2 0.42 10.9 0.0 2.9 3 0 0 3 3 3 0 1,3-beta-glucan synthase subunit FKS1, domain-1 DWNN PF08783.11 EST47311.1 - 0.38 11.1 6.2 2.4 8.5 0.4 3.7 3 0 0 3 3 3 0 DWNN domain CH_2 PF06294.11 EST47315.1 - 0.1 12.7 1.0 0.34 11.0 0.3 2.0 1 1 2 3 3 3 0 CH-like domain in sperm protein KA1 PF02149.19 EST47316.1 - 0.044 13.6 0.2 13 5.6 0.0 3.2 3 0 0 3 3 3 0 Kinase associated domain 1 Mlf1IP PF10248.9 EST47319.1 - 4.5e-12 46.3 8.0 5.5e-12 46.0 8.0 1.1 1 0 0 1 1 1 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein DER1 PF04511.15 EST47320.1 - 9.8e-21 74.5 9.0 1.2e-20 74.3 9.0 1.1 1 0 0 1 1 1 1 Der1-like family Ras PF00071.22 EST47321.1 - 2.3e-49 167.1 0.0 2.6e-49 166.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EST47321.1 - 1.2e-23 83.6 0.0 1.8e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EST47321.1 - 1.5e-05 24.5 0.0 2.3e-05 23.9 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EST47321.1 - 0.00056 19.5 0.3 0.0048 16.5 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EST47321.1 - 0.00088 18.7 0.0 0.0019 17.6 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EST47321.1 - 0.0042 17.0 0.0 0.17 11.8 0.0 2.3 2 1 0 2 2 2 1 RsgA GTPase AAA_7 PF12775.7 EST47321.1 - 0.12 11.9 0.0 0.65 9.5 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region TniB PF05621.11 EST47321.1 - 0.14 11.6 0.1 1.8 7.9 0.0 2.5 2 1 0 3 3 3 0 Bacterial TniB protein MMR_HSR1_Xtn PF16897.5 EST47321.1 - 0.15 12.0 0.0 1.6 8.8 0.0 2.4 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain LSM PF01423.22 EST47322.1 - 1.9e-09 37.1 1.6 2.7e-09 36.6 1.6 1.3 1 0 0 1 1 1 1 LSM domain Band_7_1 PF13421.6 EST47324.1 - 0.065 12.9 0.2 0.11 12.1 0.2 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family TSC22 PF01166.18 EST47324.1 - 0.1 13.0 0.7 3.4 8.0 0.1 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family AhpC-TSA PF00578.21 EST47325.1 - 1e-26 93.3 0.0 1.4e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EST47325.1 - 6.1e-09 35.7 0.0 9e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EST47325.1 - 0.0022 17.8 0.1 0.0049 16.7 0.1 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Adeno_E3_CR2 PF02439.15 EST47326.1 - 0.00037 20.2 1.4 0.00068 19.3 1.4 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Vpu PF00558.19 EST47326.1 - 0.015 15.0 1.1 0.026 14.3 1.1 1.3 1 0 0 1 1 1 0 Vpu protein DAG1 PF05454.11 EST47326.1 - 0.041 13.3 0.2 0.063 12.7 0.2 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF3290 PF11694.8 EST47326.1 - 0.38 10.7 0.9 0.71 9.8 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) Syndecan PF01034.20 EST47326.1 - 0.49 10.3 2.1 0.85 9.6 2.1 1.3 1 0 0 1 1 1 0 Syndecan domain Insulin_TMD PF17870.1 EST47326.1 - 0.6 10.2 1.9 1.2 9.3 1.9 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment BMF PF15185.6 EST47328.1 - 0.031 14.0 0.1 0.038 13.7 0.1 1.2 1 0 0 1 1 1 0 Bcl-2-modifying factor, apoptosis Podoplanin PF05808.11 EST47329.1 - 2e-05 24.7 6.1 3.5e-05 24.0 6.1 1.5 1 1 0 1 1 1 1 Podoplanin CYYR1 PF10873.8 EST47329.1 - 0.00058 20.3 2.5 0.00058 20.3 2.5 4.8 2 2 1 5 5 5 1 Cysteine and tyrosine-rich protein 1 Bacteriocin_IIc PF10439.9 EST47329.1 - 0.21 11.7 2.9 0.46 10.6 2.9 1.5 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DUF3042 PF11240.8 EST47329.1 - 0.29 11.2 1.1 0.5 10.4 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) HAD_2 PF13419.6 EST47331.1 - 3.1e-25 89.3 0.0 3.6e-25 89.1 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EST47331.1 - 5.3e-11 43.2 0.2 4e-09 37.1 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EST47331.1 - 1.4e-06 28.9 0.0 1.7e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EST47331.1 - 0.0029 17.7 0.9 0.31 11.2 0.1 2.7 2 2 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EST47331.1 - 0.0036 17.3 0.0 0.0063 16.6 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like CagX PF03524.15 EST47332.1 - 0.0071 16.1 1.1 0.0094 15.7 1.1 1.2 1 0 0 1 1 1 1 Conjugal transfer protein MMADHC PF10229.9 EST47332.1 - 0.015 15.0 0.2 0.017 14.9 0.2 1.2 1 0 0 1 1 1 0 Methylmalonic aciduria and homocystinuria type D protein Bac_export_2 PF01312.19 EST47333.1 - 0.22 10.7 3.5 0.86 8.7 1.8 2.2 1 1 1 2 2 2 0 FlhB HrpN YscU SpaS Family HAD_2 PF13419.6 EST47334.1 - 3.1e-25 89.3 0.0 3.6e-25 89.1 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EST47334.1 - 5.3e-11 43.2 0.2 4e-09 37.1 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EST47334.1 - 1.4e-06 28.9 0.0 1.7e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EST47334.1 - 0.0029 17.7 0.9 0.31 11.2 0.1 2.7 2 2 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EST47334.1 - 0.0036 17.3 0.0 0.0063 16.6 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Acetyltransf_1 PF00583.25 EST47337.1 - 1.7e-17 63.7 0.0 2e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EST47337.1 - 4e-12 46.4 0.2 6.2e-12 45.8 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EST47337.1 - 2.3e-11 43.7 0.0 2.8e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EST47337.1 - 2.2e-05 24.5 0.1 3e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 EST47337.1 - 0.00043 20.4 0.0 0.00047 20.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EST47337.1 - 0.0028 17.8 0.0 0.0032 17.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 EST47337.1 - 0.0089 16.2 0.0 0.014 15.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EST47337.1 - 0.036 14.0 0.0 0.05 13.6 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein PanZ PF12568.8 EST47337.1 - 0.098 12.4 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Abhydrolase_6 PF12697.7 EST47338.1 - 1.3e-13 52.0 0.0 1.6e-13 51.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EST47338.1 - 1.7e-11 44.3 0.1 2.3e-11 43.8 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EST47338.1 - 4.1e-11 42.6 0.0 6.8e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EST47338.1 - 0.00012 22.3 0.1 0.0002 21.6 0.1 1.3 1 0 0 1 1 1 1 Thioesterase domain UPF0227 PF05728.12 EST47338.1 - 0.00026 21.0 0.1 0.0005 20.1 0.1 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Lipase_3 PF01764.25 EST47338.1 - 0.009 15.9 0.1 0.019 14.9 0.1 1.5 1 1 0 1 1 1 1 Lipase (class 3) LIDHydrolase PF10230.9 EST47338.1 - 0.017 14.7 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Esterase PF00756.20 EST47338.1 - 0.02 14.5 0.0 0.035 13.7 0.0 1.5 1 0 0 1 1 1 0 Putative esterase PGAP1 PF07819.13 EST47338.1 - 0.085 12.6 0.8 0.12 12.1 0.0 1.7 3 0 0 3 3 3 0 PGAP1-like protein Chlorophyllase2 PF12740.7 EST47338.1 - 0.092 11.6 0.3 0.17 10.7 0.3 1.4 1 1 0 1 1 1 0 Chlorophyllase enzyme DUF900 PF05990.12 EST47338.1 - 0.18 11.3 0.4 1.5 8.3 0.4 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) AAA PF00004.29 EST47339.1 - 5.1e-37 127.2 0.0 8.7e-37 126.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EST47339.1 - 7.9e-08 32.0 0.0 1.9e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EST47339.1 - 6.5e-07 29.2 0.0 1.6e-06 28.0 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Vps4_C PF09336.10 EST47339.1 - 8e-07 29.0 0.0 2.4e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_5 PF07728.14 EST47339.1 - 7.9e-06 25.9 0.0 5.1e-05 23.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EST47339.1 - 0.00038 20.6 0.0 0.00084 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 EST47339.1 - 0.00085 18.6 0.0 0.0017 17.6 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 EST47339.1 - 0.0012 18.6 0.0 0.0023 17.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 EST47339.1 - 0.0013 18.9 0.0 0.0031 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EST47339.1 - 0.0013 19.2 0.5 0.018 15.6 0.5 2.7 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EST47339.1 - 0.0097 15.3 0.2 0.052 12.9 0.1 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.17 EST47339.1 - 0.028 13.5 0.1 0.053 12.6 0.1 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 EST47339.1 - 0.032 14.5 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EST47339.1 - 0.04 13.4 0.1 0.27 10.7 0.1 2.2 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA_14 PF13173.6 EST47339.1 - 0.041 13.9 0.1 0.9 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EST47339.1 - 0.046 14.1 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 EST47339.1 - 0.072 13.5 0.4 0.35 11.2 0.1 2.6 2 1 0 2 2 1 0 AAA ATPase domain AAA_24 PF13479.6 EST47339.1 - 0.074 12.8 0.1 0.28 10.9 0.1 2.1 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EST47339.1 - 0.088 13.1 0.2 2.7 8.3 0.0 2.4 1 1 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EST47339.1 - 0.098 13.1 0.1 0.36 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain Ndc1_Nup PF09531.10 EST47339.1 - 0.17 10.6 0.7 0.25 10.0 0.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ABC_tran PF00005.27 EST47339.1 - 0.23 12.0 0.6 3.1 8.3 0.0 2.5 2 0 0 2 2 2 0 ABC transporter ALS2CR11 PF15729.5 EST47341.1 - 0.082 12.0 11.4 0.097 11.8 11.4 1.0 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 candidate 11 MIase PF02426.16 EST47341.1 - 3.4 7.9 6.1 2.8 8.2 0.6 2.5 2 1 0 2 2 2 0 Muconolactone delta-isomerase DUF1842 PF08896.10 EST47342.1 - 0.1 12.9 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1842) DUF2222 PF09984.9 EST47345.1 - 0.00071 19.5 0.4 0.002 18.0 0.4 1.7 1 0 0 1 1 1 1 Uncharacterised signal transduction histidine kinase domain (DUF2222) Uteroglobin PF01099.17 EST47345.1 - 0.021 15.1 0.6 0.69 10.3 0.0 3.1 2 1 0 2 2 2 0 Uteroglobin family zf-CHY PF05495.12 EST47346.1 - 1.8e-15 57.2 21.1 1.8e-15 57.2 21.1 3.1 2 1 0 2 2 2 1 CHY zinc finger zf-C3HC4_2 PF13923.6 EST47346.1 - 1.1e-07 31.6 7.9 1.1e-07 31.6 7.9 5.0 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EST47346.1 - 1.8e-06 28.1 9.3 1.8e-06 28.1 9.3 4.6 3 2 1 4 4 4 2 Ring finger domain zf-RING_UBOX PF13445.6 EST47346.1 - 3.5e-05 23.7 3.0 3.5e-05 23.7 3.0 4.7 5 1 1 6 6 6 1 RING-type zinc-finger zf-RING_5 PF14634.6 EST47346.1 - 0.002 18.1 5.3 0.002 18.1 5.3 5.5 3 2 1 4 4 4 1 zinc-RING finger domain Rota_NSP3 PF01665.16 EST47351.1 - 0.079 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Rotavirus non-structural protein NSP3 Aa_trans PF01490.18 EST47354.1 - 1.4e-06 27.3 35.3 0.0033 16.2 0.1 2.2 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Orai-1 PF07856.12 EST47354.1 - 0.028 14.1 0.4 0.028 14.1 0.4 2.0 2 1 0 2 2 2 0 Mediator of CRAC channel activity SF-assemblin PF06705.11 EST47355.1 - 0.41 10.0 33.7 2.9 7.2 24.6 2.5 1 1 0 1 1 1 0 SF-assemblin/beta giardin TcdB_N PF12918.7 EST47355.1 - 5.2 7.4 13.6 2.7 8.3 1.8 3.6 4 0 0 4 4 4 0 TcdB toxin N-terminal helical domain SLATT_6 PF18169.1 EST47355.1 - 8.2 6.0 8.6 0.9 9.1 1.5 2.5 1 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 6 YL1_C PF08265.11 EST47356.1 - 0.0009 19.0 0.1 0.002 17.8 0.1 1.6 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain eRF1_1 PF03463.15 EST47357.1 - 3.8e-18 65.7 1.4 3.8e-18 65.7 1.4 1.7 2 0 0 2 2 2 1 eRF1 domain 1 eRF1_3 PF03465.15 EST47357.1 - 0.00047 20.6 1.6 0.036 14.5 0.2 3.2 3 1 0 3 3 3 1 eRF1 domain 3 ResIII PF04851.15 EST47358.1 - 2e-12 47.4 0.3 2e-12 47.4 0.3 3.9 3 1 2 5 5 5 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EST47358.1 - 2e-11 43.9 4.3 7.3e-09 35.6 0.0 3.2 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EST47358.1 - 1.7e-08 34.8 4.6 2e-08 34.6 0.7 3.2 1 1 2 3 3 3 1 Helicase conserved C-terminal domain Helicase_RecD PF05127.14 EST47358.1 - 0.0093 15.8 0.1 0.19 11.6 0.0 2.6 2 0 0 2 2 2 1 Helicase T2SSE PF00437.20 EST47358.1 - 0.023 13.8 0.0 0.067 12.2 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_22 PF13401.6 EST47358.1 - 0.024 14.9 3.0 0.51 10.6 0.0 3.0 3 1 0 3 3 3 0 AAA domain AAA PF00004.29 EST47358.1 - 2.6 8.4 5.1 6 7.3 0.5 3.4 3 2 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Peptidase_C37 PF05416.12 EST47359.1 - 0.079 11.5 0.2 0.12 10.9 0.2 1.2 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Ribosomal_L13 PF00572.18 EST47360.1 - 3.8e-08 33.6 0.1 5.4e-06 26.7 0.1 2.6 1 1 0 1 1 1 1 Ribosomal protein L13 ERCC3_RAD25_C PF16203.5 EST47361.1 - 2.4e-58 197.3 3.3 4.1e-50 170.3 0.6 2.7 3 0 0 3 3 3 2 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 EST47361.1 - 8e-16 58.3 0.1 3.1e-15 56.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Helicase_C PF00271.31 EST47361.1 - 5.4e-11 42.8 0.6 7.9e-10 39.1 0.1 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EST47361.1 - 2.1e-10 40.9 6.5 1.8e-09 37.8 0.1 3.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit PCMT PF01135.19 EST47361.1 - 0.028 14.2 0.0 0.084 12.6 0.0 1.8 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Mad3_BUB1_I_2 PF17014.5 EST47361.1 - 0.67 10.1 5.1 0.21 11.7 1.6 2.0 2 0 0 2 2 2 0 Putative Mad3/BUB1 like region 1 protein Ribosomal_L13 PF00572.18 EST47362.1 - 0.0017 18.6 0.1 0.0046 17.2 0.0 1.7 2 1 0 2 2 2 1 Ribosomal protein L13 zf-CHY PF05495.12 EST47364.1 - 7.6e-12 45.6 24.4 7.6e-12 45.6 24.4 3.9 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 EST47364.1 - 1.9e-05 24.9 15.9 1.9e-05 24.9 15.9 5.2 4 1 1 5 5 5 1 Ring finger domain ZZ PF00569.17 EST47366.1 - 0.0012 18.7 8.7 0.0012 18.7 8.7 2.7 2 0 0 2 2 2 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 EST47366.1 - 0.014 15.6 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Ets PF00178.22 EST47366.1 - 0.14 12.7 4.9 0.51 10.8 0.2 3.0 2 0 0 2 2 2 0 Ets-domain zf-UBP_var PF17807.1 EST47366.1 - 2.5 7.9 8.6 7.9 6.3 6.7 2.9 2 1 0 2 2 2 0 Variant UBP zinc finger zf-CHY PF05495.12 EST47367.1 - 3.4e-15 56.3 21.1 3.4e-15 56.3 21.1 4.0 2 1 1 3 3 3 1 CHY zinc finger zf-C3HC4_2 PF13923.6 EST47367.1 - 1.8e-07 30.9 7.9 1.8e-07 30.9 7.9 5.8 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EST47367.1 - 2.7e-06 27.6 9.1 2.7e-06 27.6 9.1 5.6 4 1 1 5 5 5 2 Ring finger domain zinc_ribbon_6 PF14599.6 EST47367.1 - 0.00049 20.1 7.1 0.00049 20.1 7.1 3.5 2 1 1 3 3 3 1 Zinc-ribbon zf-RING_5 PF14634.6 EST47367.1 - 0.0031 17.4 5.3 0.0031 17.4 5.3 6.6 4 3 0 4 4 4 1 zinc-RING finger domain DUF4231 PF14015.6 EST47371.1 - 9.6 6.7 13.1 0.093 13.2 3.1 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF4231) VSP PF03302.13 EST47372.1 - 4.3e-12 45.6 108.6 8.1e-09 34.8 43.9 4.2 1 1 3 4 4 4 3 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST47372.1 - 0.009 16.2 4.0 0.009 16.2 4.0 7.7 1 1 7 8 8 8 6 Furin-like repeat, cysteine-rich VSP PF03302.13 EST47373.1 - 4.4e-14 52.1 139.6 2e-08 33.5 43.8 5.3 1 1 4 5 5 5 5 Giardia variant-specific surface protein Secapin PF17521.2 EST47373.1 - 1.6 8.6 6.0 12 5.8 0.5 3.3 2 0 0 2 2 2 0 Honey bee peptides Peptidase_M9_N PF08453.10 EST47375.1 - 0.028 14.1 0.2 0.22 11.2 0.3 2.4 2 0 0 2 2 2 0 Peptidase family M9 N-terminal FAD_SOX PF18371.1 EST47375.1 - 0.14 12.5 0.2 0.44 10.9 0.2 1.9 1 0 0 1 1 1 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase AAA PF00004.29 EST47377.1 - 2.6e-38 131.4 0.0 4.3e-38 130.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EST47377.1 - 2.5e-06 27.5 0.0 6.7e-06 26.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 EST47377.1 - 4.5e-06 26.4 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EST47377.1 - 2.6e-05 24.7 0.1 0.00019 21.9 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 EST47377.1 - 4.4e-05 23.7 0.0 0.00011 22.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EST47377.1 - 9.9e-05 22.6 0.1 0.024 14.9 0.0 2.6 1 1 1 2 2 2 1 AAA domain Prot_ATP_ID_OB PF16450.5 EST47377.1 - 0.00013 21.9 0.0 0.00049 20.0 0.0 2.0 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain RuvB_N PF05496.12 EST47377.1 - 0.003 17.3 0.0 0.0062 16.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 EST47377.1 - 0.0086 15.4 0.0 3.6 6.9 0.0 2.3 1 1 0 2 2 2 2 KaiC IstB_IS21 PF01695.17 EST47377.1 - 0.015 15.0 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 EST47377.1 - 0.016 15.4 0.0 0.042 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EST47377.1 - 0.023 14.7 0.0 0.052 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EST47377.1 - 0.025 14.1 0.1 0.14 11.8 0.0 2.0 1 1 0 2 2 2 0 AAA domain DUF3510 PF12022.8 EST47377.1 - 0.033 14.6 0.1 0.064 13.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) DUF815 PF05673.13 EST47377.1 - 0.035 13.3 0.0 0.058 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 EST47377.1 - 0.038 14.4 0.0 0.077 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 EST47377.1 - 0.058 13.9 0.0 0.1 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EST47377.1 - 0.067 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF489 PF04356.12 EST47377.1 - 0.079 13.0 0.1 0.35 10.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF489) AAA_24 PF13479.6 EST47377.1 - 0.089 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EST47377.1 - 0.11 11.9 0.0 0.96 8.9 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein TIP49 PF06068.13 EST47377.1 - 0.15 11.2 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Trimer_CC PF08954.11 EST47381.1 - 0.41 10.2 4.1 0.24 11.0 0.5 2.2 2 0 0 2 2 2 0 Trimerisation motif ImcF-related_N PF14331.6 EST47383.1 - 0.043 13.2 0.4 0.054 12.8 0.4 1.2 1 0 0 1 1 1 0 ImcF-related N-terminal domain HMMR_N PF15905.5 EST47383.1 - 0.049 13.1 0.6 3.3 7.1 0.1 2.2 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF5549 PF17703.1 EST47383.1 - 0.055 13.1 1.0 0.096 12.3 1.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5549) SHIPPO-rpt PF07004.12 EST47383.1 - 1.3 10.1 4.9 4.6 8.3 0.0 3.5 3 0 0 3 3 3 0 Sperm-tail PG-rich repeat Metallophos PF00149.28 EST47384.1 - 7.9e-13 49.4 0.0 1.5e-12 48.5 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EST47384.1 - 5.8e-09 36.4 0.1 3.8e-07 30.4 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 EST47384.1 - 0.11 11.9 0.0 5.6 6.2 0.0 2.8 2 1 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily Ank_2 PF12796.7 EST47386.1 - 2.9e-11 43.8 0.5 6.6e-06 26.6 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EST47386.1 - 4.1e-09 36.8 0.1 0.00027 21.5 0.0 3.1 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EST47386.1 - 0.00036 20.8 0.0 0.33 11.3 0.0 4.3 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EST47386.1 - 0.0016 18.8 0.9 0.63 10.8 0.0 4.7 5 1 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 EST47386.1 - 0.013 16.0 0.1 5 7.7 0.0 3.6 3 1 0 3 3 3 0 Ankyrin repeat FimH_man-bind PF09160.10 EST47386.1 - 0.13 12.0 0.1 0.21 11.2 0.1 1.3 1 0 0 1 1 1 0 FimH, mannose binding NACHT PF05729.12 EST47389.1 - 0.0052 16.7 0.3 0.017 15.0 0.0 2.2 2 1 0 2 2 2 1 NACHT domain Mst1_SARAH PF11629.8 EST47389.1 - 0.066 13.3 1.8 0.35 11.0 1.8 2.3 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 AAA_19 PF13245.6 EST47389.1 - 0.098 13.0 0.0 0.64 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EST47389.1 - 0.1 12.7 0.2 0.55 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EST47389.1 - 0.11 12.9 0.0 0.38 11.1 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_11 PF13086.6 EST47389.1 - 0.53 10.0 0.0 0.53 10.0 0.0 4.0 3 1 1 4 4 4 0 AAA domain DUF1515 PF07439.11 EST47389.1 - 1.6 8.8 3.8 1.9 8.5 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Tropomyosin_1 PF12718.7 EST47389.1 - 2.5 8.3 43.0 1 9.5 6.7 4.6 2 1 2 4 4 4 0 Tropomyosin like Metallophos PF00149.28 EST47391.1 - 6.2e-13 49.7 0.0 1.1e-12 48.9 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EST47391.1 - 5.4e-09 36.5 0.1 3.8e-07 30.4 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 EST47391.1 - 0.091 12.1 0.0 5.6 6.2 0.0 2.8 2 1 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily ImcF-related_N PF14331.6 EST47392.1 - 0.037 13.4 0.3 0.047 13.0 0.3 1.2 1 0 0 1 1 1 0 ImcF-related N-terminal domain SHIPPO-rpt PF07004.12 EST47392.1 - 0.038 14.9 0.4 4.6 8.3 0.0 3.4 3 0 0 3 3 3 0 Sperm-tail PG-rich repeat HMMR_N PF15905.5 EST47392.1 - 0.11 12.0 2.6 3.7 6.9 0.2 2.5 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal RNA_pol_Rpb5_C PF01191.19 EST47394.1 - 0.083 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain Cytochrom_B_N_2 PF13631.6 EST47397.1 - 0.027 14.5 0.1 0.028 14.4 0.1 1.0 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Phage_spike_2 PF18781.1 EST47397.1 - 0.031 14.3 0.2 0.053 13.6 0.2 1.3 1 0 0 1 1 1 0 Phage spike trimer BCA_ABC_TP_C PF12399.8 EST47397.1 - 0.15 12.0 1.1 0.27 11.2 1.1 1.4 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter Pox_A14 PF05767.12 EST47398.1 - 0.037 14.2 1.2 0.12 12.5 0.1 2.3 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 DUF846 PF05832.12 EST47399.1 - 8.6e-25 87.4 6.1 1.1e-24 87.0 6.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) HELP PF03451.14 EST47399.1 - 5.9 6.8 5.6 7.8 6.4 0.4 2.3 2 0 0 2 2 2 0 HELP motif HMw1_D2 PF18254.1 EST47400.1 - 0.23 11.9 1.4 1.4 9.4 0.4 2.6 3 0 0 3 3 3 0 HMW1 domain 2 Ycf70 PF17382.2 EST47400.1 - 0.45 10.9 3.3 2.9 8.4 0.3 2.4 2 0 0 2 2 2 0 Uncharacterized Ycf70-like PTH2 PF01981.16 EST47401.1 - 8.1e-18 64.8 0.1 1.2e-17 64.3 0.1 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 tRNA-synt_2c PF01411.19 EST47402.1 - 1.3e-58 198.9 0.0 4.2e-27 94.9 0.0 3.1 2 1 1 3 3 3 3 tRNA synthetases class II (A) tRNA_SAD PF07973.14 EST47402.1 - 3e-10 40.0 1.3 7.2e-10 38.8 1.3 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Peptidase_M24 PF00557.24 EST47403.1 - 2.4e-38 131.9 0.0 3e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Ank_2 PF12796.7 EST47404.1 - 1.4e-46 156.9 13.8 1.6e-12 47.8 0.6 8.4 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EST47404.1 - 6.5e-24 83.7 3.2 0.00057 20.1 0.1 10.5 6 3 6 12 12 12 6 Ankyrin repeats (many copies) Ank PF00023.30 EST47404.1 - 1.1e-21 76.2 1.6 0.00053 20.3 0.1 9.4 8 1 1 9 9 9 4 Ankyrin repeat Ank_4 PF13637.6 EST47404.1 - 2.7e-18 66.1 7.9 0.0059 17.2 0.0 9.6 8 4 2 10 10 10 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EST47404.1 - 7.9e-18 62.7 6.4 0.29 11.8 0.0 11.9 12 1 1 13 13 13 4 Ankyrin repeat Fer4 PF00037.27 EST47405.1 - 6.7e-11 41.5 12.9 2.2e-05 24.1 4.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 EST47405.1 - 7.2e-07 29.3 13.3 0.0025 17.9 1.9 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 EST47405.1 - 7.2e-07 29.7 28.5 2.5e-05 24.8 16.8 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EST47405.1 - 1.2e-06 28.6 15.7 8.4e-05 22.6 16.1 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EST47405.1 - 3.1e-06 27.2 15.6 5e-06 26.6 15.6 1.3 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 EST47405.1 - 9.2e-06 25.5 15.8 0.011 15.7 5.2 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 EST47405.1 - 1.2e-05 26.1 12.7 0.0026 18.7 3.5 2.1 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_2 PF12797.7 EST47405.1 - 8e-05 22.5 14.6 0.023 14.8 3.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 EST47405.1 - 0.0014 19.1 13.8 0.051 14.1 2.5 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_22 PF17179.4 EST47405.1 - 0.0041 17.9 10.8 0.24 12.3 1.2 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 EST47405.1 - 0.074 13.6 19.0 0.16 12.5 4.1 2.5 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_8 PF13183.6 EST47405.1 - 0.09 13.2 18.7 0.7 10.4 5.1 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 EST47405.1 - 0.41 11.7 20.7 0.53 11.4 5.6 2.6 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_13 PF13370.6 EST47405.1 - 1.4 9.5 16.7 0.51 10.9 4.5 2.4 2 1 1 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 EST47405.1 - 3.1 8.6 16.5 4.9 8.0 3.8 2.6 2 1 0 2 2 2 0 4Fe-4S single cluster domain zf-DNA_Pol PF08996.10 EST47408.1 - 0.086 12.6 1.2 0.12 12.1 1.2 1.2 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger Nucleoporin_FG PF13634.6 EST47408.1 - 1.2 10.0 27.6 3.3 8.6 27.6 1.7 1 1 0 1 1 1 0 Nucleoporin FG repeat region PTPLA PF04387.14 EST47409.1 - 6.6e-26 91.0 14.3 7e-25 87.7 14.3 2.0 1 1 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Pox_I5 PF04713.12 EST47409.1 - 0.016 15.2 2.5 0.047 13.7 0.1 2.5 2 0 0 2 2 2 0 Poxvirus protein I5 DUF4485 PF14846.6 EST47410.1 - 2.2e-05 24.4 0.3 2.2e-05 24.4 0.3 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4485) NYD-SP28_assoc PF14775.6 EST47411.1 - 0.059 13.5 0.5 8.1 6.6 0.0 2.3 2 0 0 2 2 2 0 Sperm tail C-terminal domain Cofilin_ADF PF00241.20 EST47412.1 - 1.1e-17 64.0 0.1 1.3e-17 63.7 0.1 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Peptidase_S66 PF02016.15 EST47412.1 - 0.068 13.3 0.0 0.089 12.9 0.0 1.3 1 0 0 1 1 1 0 LD-carboxypeptidase N-terminal domain NIF3 PF01784.18 EST47413.1 - 2.3e-32 112.6 0.0 3.3e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) DUF3884 PF13024.6 EST47413.1 - 0.012 15.2 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3884) P53 PF00870.18 EST47415.1 - 0.18 11.6 3.6 1.3 8.8 0.1 2.6 2 1 1 3 3 3 0 P53 DNA-binding domain Calycin_like PF13944.6 EST47415.1 - 0.34 11.2 5.5 0.52 10.6 0.3 2.8 1 1 1 2 2 2 0 Calycin-like beta-barrel domain Pox_H7 PF04787.12 EST47416.1 - 0.096 13.2 0.1 0.15 12.6 0.1 1.3 1 0 0 1 1 1 0 Late protein H7 DUF826 PF05696.11 EST47418.1 - 0.013 15.6 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF826) Pkinase PF00069.25 EST47420.1 - 3.5e-65 220.0 0.4 4.9e-65 219.5 0.4 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST47420.1 - 2.7e-45 154.7 0.2 3.9e-45 154.2 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EST47420.1 - 5.4e-09 35.8 0.1 1.2e-08 34.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EST47420.1 - 0.0023 16.8 0.0 0.0062 15.4 0.0 1.6 1 1 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EST47420.1 - 0.019 13.9 0.9 0.034 13.1 0.9 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DUF3552 PF12072.8 EST47420.1 - 0.4 10.1 8.9 0.59 9.5 3.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) HSBP1 PF06825.12 EST47421.1 - 1e-12 47.7 0.3 1.1e-12 47.5 0.3 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 BLOC1_2 PF10046.9 EST47421.1 - 0.00033 20.9 0.5 0.00039 20.7 0.5 1.1 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 EST47421.1 - 0.0021 18.1 0.2 0.0025 17.9 0.2 1.0 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_GPO PF05929.11 EST47421.1 - 0.0074 15.9 0.1 0.0074 15.9 0.1 1.0 1 0 0 1 1 1 1 Phage capsid scaffolding protein (GPO) serine peptidase Hormone_3 PF00159.18 EST47421.1 - 0.012 15.6 0.0 0.036 14.1 0.1 1.7 2 0 0 2 2 2 0 Pancreatic hormone peptide FlaC_arch PF05377.11 EST47421.1 - 0.015 15.7 0.8 1.3 9.4 0.1 2.1 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF948 PF06103.11 EST47421.1 - 0.023 14.9 0.6 0.07 13.4 0.6 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Glycos_transf_3 PF00591.21 EST47421.1 - 0.024 14.3 0.1 0.027 14.1 0.1 1.0 1 0 0 1 1 1 0 Glycosyl transferase family, a/b domain PMC2NT PF08066.12 EST47421.1 - 0.024 15.3 0.3 0.027 15.1 0.3 1.1 1 0 0 1 1 1 0 PMC2NT (NUC016) domain Laminin_II PF06009.12 EST47421.1 - 0.045 13.8 0.6 0.058 13.4 0.6 1.2 1 1 0 1 1 1 0 Laminin Domain II DUF4559 PF15112.6 EST47421.1 - 0.049 13.3 0.6 0.051 13.2 0.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Gp-FAR-1 PF05823.12 EST47421.1 - 0.053 13.9 0.1 0.054 13.9 0.1 1.1 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Zw10 PF06248.13 EST47421.1 - 0.062 11.9 0.1 0.063 11.8 0.1 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 YtxH PF12732.7 EST47421.1 - 0.078 13.5 0.3 0.14 12.7 0.3 1.4 1 1 0 1 1 1 0 YtxH-like protein DALR_1 PF05746.15 EST47421.1 - 0.086 13.0 0.0 0.11 12.7 0.0 1.3 1 1 0 1 1 1 0 DALR anticodon binding domain DUF1757 PF08560.10 EST47422.1 - 0.045 13.8 0.1 0.1 12.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1757) SMC_N PF02463.19 EST47424.1 - 3.5e-13 49.5 38.1 4.7e-11 42.5 38.1 4.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EST47424.1 - 2.7e-08 34.6 27.2 2.7e-08 34.6 27.2 6.7 1 1 5 6 6 6 1 AAA domain AAA_15 PF13175.6 EST47424.1 - 1.7e-05 24.7 17.8 1.7e-05 24.7 17.8 4.3 1 1 3 4 4 4 1 AAA ATPase domain AAA_29 PF13555.6 EST47424.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF211 PF02680.14 EST47424.1 - 0.82 9.9 12.1 0.42 10.8 0.6 4.9 5 0 0 5 5 5 0 Uncharacterized ArCR, COG1888 AAA_21 PF13304.6 EST47424.1 - 1.1 9.0 15.8 0.16 11.7 0.1 3.9 4 1 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF3613 PF12266.8 EST47425.1 - 0.89 9.4 5.5 0.28 11.0 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3613) DnaI_N PF07319.11 EST47427.1 - 0.052 14.2 5.1 0.61 10.8 1.7 2.8 2 1 1 3 3 3 0 Primosomal protein DnaI N-terminus Ribosomal_L34e PF01199.18 EST47428.1 - 1.9e-17 63.4 3.2 1.9e-17 63.4 3.2 1.4 2 0 0 2 2 2 1 Ribosomal protein L34e SLATT_4 PF18186.1 EST47429.1 - 0.037 13.7 0.5 0.052 13.2 0.5 1.3 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 DUSP PF06337.12 EST47431.1 - 1.9e-09 38.0 0.6 1.9e-09 38.0 0.6 4.6 3 3 0 3 3 3 1 DUSP domain LRR_4 PF12799.7 EST47431.1 - 0.00061 20.1 12.9 0.0059 17.0 1.5 3.4 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EST47431.1 - 0.39 10.5 17.8 1.7 8.5 6.9 3.8 1 1 1 2 2 2 0 Leucine rich repeat LRR_1 PF00560.33 EST47431.1 - 2 9.3 15.3 5.8 7.9 0.1 5.0 5 0 0 5 5 5 0 Leucine Rich Repeat Fer4_12 PF13353.6 EST47432.1 - 4.3e-07 30.3 0.0 1.6e-06 28.4 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain Radical_SAM PF04055.21 EST47432.1 - 8.4e-06 26.3 0.3 3.2e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.6 EST47432.1 - 0.00026 21.1 2.3 0.00027 21.1 0.0 2.1 2 1 0 2 2 2 1 4Fe-4S single cluster domain YjcZ PF13990.6 EST47432.1 - 0.04 13.3 0.0 2.4 7.5 0.0 2.1 2 0 0 2 2 2 0 YjcZ-like protein EF-hand_7 PF13499.6 EST47433.1 - 0.0018 18.7 0.5 0.14 12.7 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain pair Cut12 PF11500.8 EST47434.1 - 0.13 12.2 0.7 0.25 11.3 0.7 1.4 1 0 0 1 1 1 0 Spindle pole body formation-associated protein RolB_RolC PF02027.17 EST47435.1 - 0.081 12.6 1.4 0.14 11.8 1.4 1.4 1 0 0 1 1 1 0 RolB/RolC glucosidase family IBV_3A PF03617.13 EST47435.1 - 0.083 12.9 0.8 0.083 12.9 0.8 2.9 1 1 1 2 2 2 0 IBV 3A protein INT_SG_DDX_CT_C PF15300.6 EST47435.1 - 0.096 12.5 0.0 0.43 10.4 0.0 2.1 2 0 0 2 2 2 0 INTS6/SAGE1/DDX26B/CT45 C-terminus CaMKII_AD PF08332.10 EST47435.1 - 0.14 12.3 0.1 2.7 8.1 0.0 2.7 2 1 1 3 3 3 0 Calcium/calmodulin dependent protein kinase II association domain TP_methylase PF00590.20 EST47436.1 - 3.1e-21 76.3 0.0 3.5e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DHHC PF01529.20 EST47437.1 - 1.5e-20 73.7 24.6 1.5e-20 73.7 24.6 2.8 1 1 1 2 2 2 1 DHHC palmitoyltransferase IncFII_repA PF02387.15 EST47439.1 - 0.0015 17.9 0.4 0.0017 17.7 0.4 1.1 1 0 0 1 1 1 1 IncFII RepA protein family TMEM214 PF10151.9 EST47439.1 - 0.012 14.1 0.7 0.014 13.9 0.7 1.0 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator DUF2975 PF11188.8 EST47439.1 - 0.015 15.2 0.1 0.017 15.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) DUF4201 PF13870.6 EST47439.1 - 0.026 14.2 3.9 0.03 14.1 3.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) TSC22 PF01166.18 EST47439.1 - 0.095 13.0 4.9 1 9.7 1.2 2.3 1 1 1 2 2 2 0 TSC-22/dip/bun family PrpF PF04303.13 EST47439.1 - 0.11 11.5 0.1 0.12 11.3 0.1 1.0 1 0 0 1 1 1 0 PrpF protein GIT_CC PF16559.5 EST47439.1 - 0.77 9.7 5.3 0.6 10.0 2.5 1.8 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor RRM_1 PF00076.22 EST47440.1 - 3.1e-12 46.1 0.0 4.9e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EST47440.1 - 0.0089 16.0 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Myotub-related PF06602.14 EST47440.1 - 0.066 12.1 0.0 0.069 12.1 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain KorB_C PF06613.11 EST47440.1 - 0.17 11.9 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 KorB C-terminal beta-barrel domain Indigoidine_A PF04227.12 EST47441.1 - 0.1 12.0 0.0 0.12 11.8 0.0 1.0 1 0 0 1 1 1 0 Indigoidine synthase A like protein Pkinase PF00069.25 EST47442.1 - 3.8e-44 151.0 0.1 3.8e-44 151.0 0.1 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST47442.1 - 6.8e-24 84.5 0.0 6.8e-24 84.5 0.0 1.8 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EST47442.1 - 2.1e-06 27.9 0.0 0.054 13.4 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EST47442.1 - 7.2e-06 25.5 0.1 1.6e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EST47442.1 - 1.3e-05 24.9 1.8 2.4e-05 24.0 0.1 2.3 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 EST47442.1 - 0.00018 20.4 11.1 0.00099 18.0 10.6 2.2 1 1 0 1 1 1 1 Fungal protein kinase TFIIA PF03153.13 EST47442.1 - 0.2 11.6 38.9 0.28 11.1 38.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 EST47442.1 - 9.6 4.3 32.0 14 3.8 32.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF948 PF06103.11 EST47443.1 - 8 6.8 7.8 3.2 8.1 0.9 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Adeno_IVa2 PF02456.15 EST47444.1 - 0.055 12.3 0.3 0.071 11.9 0.3 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein YhfH PF14149.6 EST47445.1 - 0.2 11.6 7.5 0.2 11.7 0.5 3.2 3 0 0 3 3 3 0 YhfH-like protein zf-MIZ PF02891.20 EST47446.1 - 2e-06 27.4 0.1 4.7e-06 26.3 0.1 1.7 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 EST47446.1 - 0.00087 19.1 1.2 0.0013 18.5 0.3 1.7 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit PTPS PF01242.19 EST47447.1 - 0.0043 17.0 0.5 0.01 15.8 0.2 1.8 2 0 0 2 2 2 1 6-pyruvoyl tetrahydropterin synthase PDZ PF00595.24 EST47447.1 - 0.022 15.1 0.2 0.13 12.6 0.1 2.2 2 0 0 2 2 2 0 PDZ domain Prismane PF03063.20 EST47448.1 - 2.8e-67 227.6 1.5 3.3e-67 227.3 1.5 1.1 1 0 0 1 1 1 1 Prismane/CO dehydrogenase family DSPc PF00782.20 EST47449.1 - 0.00047 20.0 0.0 0.0006 19.6 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain AtuA PF07287.11 EST47449.1 - 0.16 10.6 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 Acyclic terpene utilisation family protein AtuA Homeodomain PF00046.29 EST47449.1 - 0.46 10.4 2.4 12 5.8 0.1 2.7 3 0 0 3 3 3 0 Homeodomain HALZ PF02183.18 EST47450.1 - 0.0059 16.8 1.3 0.0059 16.8 1.3 6.4 6 1 1 7 7 7 1 Homeobox associated leucine zipper ADIP PF11559.8 EST47450.1 - 0.012 15.7 8.8 0.012 15.7 8.8 5.7 1 1 5 6 6 6 0 Afadin- and alpha -actinin-Binding EF-hand_1 PF00036.32 EST47451.1 - 0.00069 19.0 0.1 0.48 10.1 0.0 2.9 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 EST47451.1 - 0.00074 18.9 0.0 0.0021 17.4 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EST47451.1 - 0.0019 18.0 0.3 0.05 13.5 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 EST47451.1 - 0.0037 17.7 0.1 0.14 12.6 0.0 2.5 2 1 0 2 2 2 1 EF-hand domain pair Pkinase PF00069.25 EST47452.1 - 2.7e-17 63.0 0.1 4.7e-13 49.1 0.1 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EST47452.1 - 1.1e-05 24.9 1.1 0.00023 20.6 0.1 2.9 3 0 0 3 3 3 1 Protein tyrosine kinase Kdo PF06293.14 EST47452.1 - 0.0018 17.6 0.8 0.0042 16.5 0.8 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EST47452.1 - 0.074 13.0 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Vps51 PF08700.11 EST47453.1 - 0.091 12.8 1.7 0.1 12.7 0.8 1.5 2 0 0 2 2 2 0 Vps51/Vps67 Ribosomal_L15e PF00827.17 EST47454.1 - 2.7e-78 262.1 4.1 3.1e-78 261.9 4.1 1.0 1 0 0 1 1 1 1 Ribosomal L15 TolA_bind_tri PF16331.5 EST47455.1 - 0.016 15.2 3.3 0.043 13.9 3.3 1.8 1 0 0 1 1 1 0 TolA binding protein trimerisation DUF5082 PF16888.5 EST47455.1 - 0.025 14.8 3.2 0.025 14.8 3.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) SlyX PF04102.12 EST47455.1 - 7.1 7.3 7.2 4 8.1 4.4 2.1 2 0 0 2 2 2 0 SlyX TTL PF03133.15 EST47456.1 - 1.7e-46 158.7 1.9 5.9e-36 124.1 0.6 2.1 1 1 1 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EST47456.1 - 3.5e-05 23.2 0.4 0.26 10.5 0.0 3.8 3 1 1 4 4 4 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EST47456.1 - 0.02 14.1 0.0 3.4 6.8 0.0 2.3 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp TB2_DP1_HVA22 PF03134.19 EST47457.1 - 8.9e-06 25.6 1.9 8.9e-06 25.6 1.9 1.7 1 1 0 1 1 1 1 TB2/DP1, HVA22 family Peptidase_S24 PF00717.23 EST47458.1 - 3.8e-05 23.6 1.6 4.3e-05 23.4 0.3 1.9 2 0 0 2 2 2 1 Peptidase S24-like Peptidase_C1 PF00112.23 EST47459.1 - 9.4e-29 101.1 1.6 2.4e-28 99.7 0.4 2.2 2 1 0 2 2 2 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EST47459.1 - 0.00098 18.0 1.1 0.0072 15.1 0.4 2.1 2 0 0 2 2 2 1 Peptidase C1-like family TNFR_16_TM PF18422.1 EST47459.1 - 0.14 12.1 1.1 0.49 10.4 1.1 1.9 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Insulin_TMD PF17870.1 EST47459.1 - 1.4 9.1 4.5 3.5 7.8 4.5 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Radial_spoke PF04712.12 EST47460.1 - 2.7e-51 175.1 43.6 1.7e-49 169.1 21.5 4.1 2 2 0 3 3 3 2 Radial spokehead-like protein DUF2976 PF11190.8 EST47461.1 - 0.088 12.6 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) Brix PF04427.18 EST47462.1 - 1.8e-19 70.6 0.9 2.4e-19 70.2 0.9 1.1 1 0 0 1 1 1 1 Brix domain IF4E PF01652.18 EST47463.1 - 1.7e-12 47.4 3.9 2.3e-12 47.0 3.9 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E PDE6_gamma PF04868.12 EST47463.1 - 0.15 12.3 0.9 0.35 11.1 0.8 1.6 1 1 0 1 1 1 0 Retinal cGMP phosphodiesterase, gamma subunit DUF4363 PF14276.6 EST47465.1 - 0.043 13.9 0.2 0.064 13.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) MFS_1 PF07690.16 EST47466.1 - 6.5e-14 51.6 54.5 1.8e-09 37.0 20.9 3.0 2 2 0 2 2 2 2 Major Facilitator Superfamily MtrG PF04210.13 EST47467.1 - 0.1 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G YqjK PF13997.6 EST47468.1 - 1.1 9.5 0.0 1.1 9.5 0.0 2.7 3 0 0 3 3 3 0 YqjK-like protein kleA_kleC PF17383.2 EST47468.1 - 2.4 8.5 4.6 46 4.4 0.0 3.6 4 0 0 4 4 4 0 Uncharacterized KorC regulated protein A Helicase_C PF00271.31 EST47469.1 - 1.2e-06 28.8 0.6 8.9e-06 26.0 0.1 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Helicase_RecD PF05127.14 EST47469.1 - 2.8e-06 27.3 0.0 7.1e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 Helicase DEAD PF00270.29 EST47469.1 - 3.3e-06 27.0 2.4 0.00025 20.9 2.4 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EST47469.1 - 8.6e-06 26.1 1.4 3.4e-05 24.1 0.2 2.6 3 1 0 3 3 3 1 AAA domain ResIII PF04851.15 EST47469.1 - 1.5e-05 25.1 0.4 0.0024 17.9 0.4 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_11 PF13086.6 EST47469.1 - 0.00017 21.5 0.8 0.091 12.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EST47469.1 - 0.00068 20.0 0.5 0.0029 17.9 0.5 2.0 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 EST47469.1 - 0.0021 17.5 0.3 0.011 15.2 0.3 2.0 1 1 0 1 1 1 1 Bacterial TniB protein AAA PF00004.29 EST47469.1 - 0.0043 17.5 0.9 0.47 10.9 0.2 2.9 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) Flavi_DEAD PF07652.14 EST47469.1 - 0.0071 16.3 0.1 0.024 14.6 0.1 1.9 1 1 0 1 1 1 1 Flavivirus DEAD domain AAA_30 PF13604.6 EST47469.1 - 0.022 14.5 0.0 0.051 13.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EST47469.1 - 0.057 13.1 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EST47469.1 - 0.07 12.9 0.0 0.23 11.2 0.0 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 EST47469.1 - 0.074 13.6 0.1 0.45 11.0 0.0 2.1 2 1 0 2 2 2 0 ABC transporter GMP_PDE_delta PF05351.11 EST47471.1 - 1.7e-22 80.2 0.0 2.3e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 GMP-PDE, delta subunit zf-C2HC_2 PF13913.6 EST47472.1 - 1.3e-07 31.4 1.2 2.6e-07 30.4 1.2 1.6 1 0 0 1 1 1 1 zinc-finger of a C2HC-type GHL13 PF14883.6 EST47472.1 - 0.0073 15.4 0.6 0.043 12.9 0.1 1.9 1 1 0 2 2 2 1 Hypothetical glycosyl hydrolase family 13 DUF2318 PF10080.9 EST47472.1 - 0.013 15.6 0.1 0.028 14.5 0.1 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) TFIIA PF03153.13 EST47472.1 - 0.88 9.5 16.4 1.1 9.2 16.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Androgen_recep PF02166.16 EST47472.1 - 9.2 5.0 12.3 12 4.6 12.3 1.1 1 0 0 1 1 1 0 Androgen receptor RICTOR_M PF14666.6 EST47474.1 - 0.071 12.9 8.1 1.5 8.6 0.7 3.4 2 2 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, middle domain DUF4470 PF14737.6 EST47474.1 - 0.48 10.6 2.9 1.1 9.5 0.1 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4470) TPR_8 PF13181.6 EST47477.1 - 2.3e-09 36.7 10.4 0.0053 16.9 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EST47477.1 - 8.1e-07 28.7 1.7 0.25 11.6 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat DnaJ PF00226.31 EST47477.1 - 1.4e-06 28.3 0.2 7.3e-06 26.0 0.0 2.4 2 0 0 2 2 2 1 DnaJ domain TPR_1 PF00515.28 EST47477.1 - 1.8e-05 24.4 7.1 0.55 10.1 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EST47477.1 - 0.0026 18.0 2.8 8.4 6.8 0.1 4.2 4 1 0 4 4 4 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 EST47477.1 - 0.014 14.9 0.2 0.076 12.5 0.2 2.4 1 0 0 1 1 1 0 SHNi-TPR CooT PF10133.9 EST47477.1 - 0.088 13.1 0.1 0.42 10.9 0.1 2.2 1 0 0 1 1 1 0 CO dehydrogenase accessory protein CooT TPR_7 PF13176.6 EST47477.1 - 0.16 12.1 0.1 14 6.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Fcf1 PF04900.12 EST47477.1 - 0.16 12.4 3.5 7.2 7.1 0.1 4.0 3 1 0 3 3 3 0 Fcf1 FNIP PF05725.12 EST47477.1 - 4.4 7.5 42.0 0.15 12.3 1.2 6.9 6 1 0 6 6 6 0 FNIP Repeat Lipase_3 PF01764.25 EST47478.1 - 3.8e-13 49.5 0.0 6.8e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Diphthamide_syn PF01866.17 EST47479.1 - 3.3e-59 200.8 0.2 3.8e-59 200.6 0.2 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein SNO PF01174.19 EST47479.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 SNO glutamine amidotransferase family DUF5493 PF17597.2 EST47480.1 - 0.12 12.6 0.0 2.5 8.4 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5493) CBM39 PF15886.5 EST47481.1 - 0.74 9.7 5.1 0.32 10.9 0.8 2.3 2 1 0 2 2 2 0 Carbohydrate binding domain (family 32) Pkinase PF00069.25 EST47482.1 - 1e-60 205.4 0.9 1.3e-40 139.5 0.1 3.0 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EST47482.1 - 1.6e-28 99.7 2.3 2.3e-25 89.4 0.0 2.9 4 0 0 4 4 4 2 Protein tyrosine kinase POLO_box PF00659.18 EST47482.1 - 3.7e-16 59.1 3.3 1.4e-12 47.6 0.3 4.0 3 0 0 3 3 3 2 POLO box duplicated region Kinase-like PF14531.6 EST47482.1 - 0.0048 16.3 0.2 0.59 9.4 0.0 3.3 2 1 0 3 3 3 1 Kinase-like Ndc80_HEC PF03801.13 EST47482.1 - 0.014 15.1 0.5 0.11 12.1 0.0 2.6 2 1 1 3 3 3 0 HEC/Ndc80p family Plectin PF00681.20 EST47482.1 - 0.16 11.8 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Plectin repeat WAC_Acf1_DNA_bd PF10537.9 EST47482.1 - 0.77 10.3 6.4 1 9.9 0.0 3.4 3 0 0 3 3 3 0 ATP-utilising chromatin assembly and remodelling N-terminal ABC_tran_CTD PF16326.5 EST47484.1 - 0.015 15.5 0.4 0.021 15.1 0.4 1.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain DUF2205 PF10224.9 EST47484.1 - 0.022 14.8 0.1 0.029 14.3 0.1 1.2 1 0 0 1 1 1 0 Short coiled-coil protein KASH_CCD PF14662.6 EST47484.1 - 0.033 14.0 0.6 0.04 13.7 0.6 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH CENP-H PF05837.12 EST47484.1 - 0.072 13.5 0.2 0.073 13.5 0.2 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF4363 PF14276.6 EST47484.1 - 0.12 12.5 1.0 0.12 12.5 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) Thioredoxin PF00085.20 EST47485.1 - 0.0023 17.9 0.0 0.0029 17.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin E2F_TDP PF02319.20 EST47486.1 - 8.8e-12 44.9 1.1 6.7e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain Cdc6_C PF09079.11 EST47486.1 - 0.011 15.7 0.0 3.3 7.8 0.0 2.3 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain HTH_Crp_2 PF13545.6 EST47486.1 - 0.077 13.0 0.0 0.34 10.9 0.0 1.9 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain E2F_TDP PF02319.20 EST47487.1 - 6.4e-15 55.0 0.1 2.2e-06 27.6 0.1 2.2 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain MarR_2 PF12802.7 EST47487.1 - 0.069 13.0 0.0 0.15 12.0 0.0 1.5 2 0 0 2 2 2 0 MarR family ABC_tran PF00005.27 EST47490.1 - 2e-14 54.3 0.1 6.4e-14 52.6 0.0 1.9 2 0 0 2 2 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EST47490.1 - 1.2e-10 41.1 32.9 1.2e-10 41.1 32.9 1.6 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 EST47490.1 - 9.8e-06 25.6 2.4 0.05 13.4 0.1 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EST47490.1 - 0.00015 21.3 2.4 0.22 10.9 0.7 2.6 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EST47490.1 - 0.0015 19.1 0.8 0.0027 18.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain RsgA_GTPase PF03193.16 EST47490.1 - 0.0021 18.0 0.3 0.004 17.1 0.3 1.4 1 0 0 1 1 1 1 RsgA GTPase NB-ARC PF00931.22 EST47490.1 - 0.0025 17.0 0.0 0.0054 16.0 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_15 PF13175.6 EST47490.1 - 0.007 16.1 0.3 0.015 15.1 0.3 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EST47490.1 - 0.018 14.7 0.1 0.044 13.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 EST47490.1 - 0.028 14.3 0.9 0.088 12.7 0.9 1.8 1 1 0 1 1 1 0 NTPase AAA_30 PF13604.6 EST47490.1 - 0.051 13.3 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EST47490.1 - 0.093 12.6 0.3 0.3 11.0 0.3 1.9 1 1 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.23 EST47490.1 - 0.14 12.3 0.2 0.43 10.7 0.2 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Tfb5 PF06331.12 EST47490.1 - 1.5 8.9 4.8 16 5.6 0.1 3.0 3 0 0 3 3 3 0 Transcription factor TFIIH complex subunit Tfb5 Trm112p PF03966.16 EST47492.1 - 1.7e-05 25.3 0.0 3.5e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 Trm112p-like protein zf_Rg PF17915.1 EST47492.1 - 0.022 14.2 0.2 0.022 14.2 0.2 1.8 2 0 0 2 2 2 0 Reverse gyrase zinc finger zf-C3HC PF07967.13 EST47492.1 - 0.034 14.2 0.8 0.079 13.0 0.8 1.5 1 1 0 1 1 1 0 C3HC zinc finger-like RTX_C PF08339.10 EST47492.1 - 0.063 13.3 0.2 0.068 13.2 0.2 1.1 1 0 0 1 1 1 0 RTX C-terminal domain DUF1682 PF07946.14 EST47492.1 - 0.071 12.3 0.1 0.072 12.3 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DiS_P_DiS PF06750.13 EST47492.1 - 0.078 13.1 0.5 1.2 9.3 0.0 2.1 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain Trm5_N PF18093.1 EST47492.1 - 0.09 12.7 1.1 1.5 8.8 0.1 2.6 2 1 1 3 3 3 0 tRNA methyltransferase 5 N-terminal domain ROS_MUCR PF05443.11 EST47492.1 - 0.1 12.7 0.1 0.12 12.4 0.1 1.2 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein zinc_ribbon_4 PF13717.6 EST47492.1 - 6.5 6.8 6.9 16 5.5 0.2 2.7 3 0 0 3 3 3 0 zinc-ribbon domain ADK PF00406.22 EST47494.1 - 2.1e-41 141.5 0.0 3e-41 141.0 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EST47494.1 - 1.2e-20 74.3 0.0 3.5e-20 72.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EST47494.1 - 0.00037 21.0 0.0 0.00064 20.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EST47494.1 - 0.014 15.8 0.0 0.024 15.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EST47494.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_28 PF13521.6 EST47494.1 - 0.027 14.7 0.0 0.042 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EST47494.1 - 0.031 14.8 0.0 0.059 13.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 EST47494.1 - 0.054 13.8 0.0 0.34 11.2 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.14 EST47494.1 - 0.082 12.9 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Dpy-30 PF05186.13 EST47494.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Dpy-30 motif DAP3 PF10236.9 EST47494.1 - 0.19 10.9 0.0 0.34 10.0 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Clat_adaptor_s PF01217.20 EST47495.1 - 1.2e-46 158.2 4.9 1.3e-46 158.0 4.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1079 PF06435.11 EST47497.1 - 0.027 14.7 2.1 0.062 13.5 2.1 1.6 1 0 0 1 1 1 0 Repeat of unknown function (DUF1079) LemA PF04011.12 EST47497.1 - 0.043 13.7 0.3 5 7.0 0.0 2.1 2 0 0 2 2 2 0 LemA family Synaptobrevin PF00957.21 EST47498.1 - 4.3e-19 68.1 6.1 4.3e-19 68.1 6.1 2.1 1 1 1 2 2 2 1 Synaptobrevin Longin PF13774.6 EST47498.1 - 7.4e-11 41.9 0.1 1.4e-10 41.0 0.1 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain RIFIN PF02009.16 EST47498.1 - 0.0042 17.0 2.4 0.0047 16.9 2.4 1.1 1 0 0 1 1 1 1 Rifin T2SSF PF00482.23 EST47498.1 - 0.0045 16.9 1.3 0.012 15.6 1.1 1.8 1 1 0 1 1 1 1 Type II secretion system (T2SS), protein F Pex24p PF06398.11 EST47498.1 - 0.023 13.7 0.5 0.026 13.5 0.5 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin BLOC1_2 PF10046.9 EST47498.1 - 0.047 14.0 3.1 0.073 13.4 2.2 1.8 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Orf78 PF06024.12 EST47498.1 - 0.56 10.5 8.1 0.7 10.2 6.0 2.2 2 1 0 2 2 2 0 Orf78 (ac78) DUF2116 PF09889.9 EST47498.1 - 4.4 7.4 7.3 3.2 7.8 4.5 2.1 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) SNARE PF05739.19 EST47498.1 - 6.8 6.8 9.9 9.4 6.3 7.1 2.6 1 1 1 2 2 2 0 SNARE domain DUF2605 PF10792.9 EST47499.1 - 0.0068 16.3 0.5 3.1 7.8 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2605) baeRF_family6 PF18848.1 EST47499.1 - 0.042 14.2 0.5 0.042 14.2 0.5 2.0 1 1 1 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 6 YEATS PF03366.16 EST47502.1 - 3.7e-13 49.2 1.1 7e-13 48.4 1.1 1.5 1 0 0 1 1 1 1 YEATS family Cob_adeno_trans PF01923.18 EST47503.1 - 0.0013 18.9 2.3 0.0013 18.9 2.3 2.7 2 1 1 3 3 3 1 Cobalamin adenosyltransferase Filament PF00038.21 EST47503.1 - 0.0088 15.7 29.7 0.084 12.4 14.0 2.3 1 1 1 2 2 2 2 Intermediate filament protein Baculo_PEP_C PF04513.12 EST47503.1 - 0.13 12.3 21.8 1.5 8.9 0.5 3.3 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF883 PF05957.13 EST47503.1 - 0.92 10.2 2.7 12 6.5 0.1 3.5 2 2 0 3 3 3 0 Bacterial protein of unknown function (DUF883) CEP63 PF17045.5 EST47503.1 - 1.8 8.4 33.4 0.52 10.2 13.5 2.3 2 0 0 2 2 2 0 Centrosomal protein of 63 kDa EF-hand_3 PF09069.11 EST47503.1 - 2.2 8.7 10.5 0.1 13.1 2.1 2.8 3 1 0 3 3 3 0 EF-hand ABC_tran_Xtn PF12848.7 EST47503.1 - 6.9 6.8 21.6 0.92 9.6 5.5 3.4 3 1 0 3 3 3 0 ABC transporter E2F_TDP PF02319.20 EST47506.1 - 6.7e-15 54.9 0.1 2.3e-06 27.6 0.1 2.2 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain MarR_2 PF12802.7 EST47506.1 - 0.072 13.0 0.0 0.15 11.9 0.0 1.5 2 0 0 2 2 2 0 MarR family E2F_TDP PF02319.20 EST47507.1 - 6.8e-11 42.1 0.7 6.7e-05 22.9 0.0 2.1 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain Cdc6_C PF09079.11 EST47507.1 - 0.0066 16.4 0.0 2 8.4 0.0 2.3 2 0 0 2 2 2 2 CDC6, C terminal winged helix domain HTH_Crp_2 PF13545.6 EST47507.1 - 0.093 12.7 0.1 0.4 10.7 0.0 1.9 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Kp4 PF09044.10 EST47508.1 - 0.047 13.8 0.1 0.093 12.8 0.1 1.6 1 0 0 1 1 1 0 Kp4 DUF211 PF02680.14 EST47508.1 - 0.076 13.2 0.6 5.1 7.3 0.0 2.8 1 1 2 3 3 3 0 Uncharacterized ArCR, COG1888 SNARE PF05739.19 EST47509.1 - 1e-09 38.2 0.4 1e-09 38.2 0.4 2.4 3 0 0 3 3 3 1 SNARE domain zf-C4H2 PF10146.9 EST47509.1 - 0.00034 21.0 6.8 0.00034 21.0 6.8 2.1 1 1 1 2 2 2 1 Zinc finger-containing protein Synaptobrevin PF00957.21 EST47509.1 - 0.0026 17.5 5.5 0.0026 17.5 5.5 3.0 2 1 2 4 4 4 1 Synaptobrevin Tropomyosin PF00261.20 EST47509.1 - 0.015 14.7 2.9 0.015 14.7 2.9 2.4 2 1 0 2 2 2 0 Tropomyosin KCT2 PF17818.1 EST47509.1 - 0.019 15.1 1.0 0.33 11.1 0.2 2.5 1 1 1 2 2 2 0 Keratinocyte-associated gene product GCP_N_terminal PF17681.1 EST47509.1 - 0.026 14.2 3.3 0.04 13.6 3.3 1.2 1 0 0 1 1 1 0 Gamma tubulin complex component N-terminal DUF3540 PF12059.8 EST47509.1 - 0.063 13.1 2.4 0.27 11.1 2.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3540) Peptidase_M16 PF00675.20 EST47509.1 - 0.61 10.0 6.8 0.39 10.7 2.3 2.3 1 1 1 2 2 2 0 Insulinase (Peptidase family M16) Asp5 PF17000.5 EST47509.1 - 0.85 9.8 0.1 0.85 9.8 0.1 2.4 2 0 0 2 2 2 0 Accessory secretory protein Sec, Asp5 DUF2207 PF09972.9 EST47509.1 - 3 6.5 10.9 30 3.2 10.9 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Tropomyosin_1 PF12718.7 EST47509.1 - 9.8 6.3 21.9 0.26 11.4 6.4 3.2 2 1 0 3 3 3 0 Tropomyosin like DUF4407 PF14362.6 EST47510.1 - 0.021 14.2 2.2 0.032 13.6 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sec8_exocyst PF04048.14 EST47510.1 - 0.05 13.5 1.3 0.1 12.5 0.1 1.9 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Phasin_2 PF09361.10 EST47510.1 - 0.065 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Phasin protein PspB PF06667.12 EST47510.1 - 0.11 12.6 1.2 0.21 11.6 1.2 1.5 1 0 0 1 1 1 0 Phage shock protein B Atg14 PF10186.9 EST47510.1 - 0.13 11.4 2.2 0.18 10.8 2.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Cauli_AT PF03233.13 EST47510.1 - 0.29 11.1 2.4 0.26 11.2 0.8 1.7 2 0 0 2 2 2 0 Aphid transmission protein Cdh1_DBD_1 PF18196.1 EST47510.1 - 0.33 11.3 4.6 0.4 11.0 0.6 2.8 2 2 0 3 3 3 0 Chromodomain helicase DNA-binding domain 1 FlaC_arch PF05377.11 EST47510.1 - 0.48 10.9 4.7 2.1 8.8 0.1 3.0 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Metal_resist PF13801.6 EST47510.1 - 1.1 9.4 4.4 1.8 8.7 4.4 1.4 1 0 0 1 1 1 0 Heavy-metal resistance DUF1971 PF09313.11 EST47514.1 - 0.054 13.5 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1971) DUF573 PF04504.14 EST47514.1 - 0.85 10.3 6.6 2.4 8.9 1.2 2.4 2 1 0 2 2 2 0 Protein of unknown function, DUF573 Carbam_trans_C PF16861.5 EST47515.1 - 0.057 13.0 0.2 0.14 11.8 0.1 1.6 2 0 0 2 2 2 0 Carbamoyltransferase C-terminus MFS_1 PF07690.16 EST47516.1 - 2.7e-19 69.3 37.7 3.7e-18 65.6 37.3 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Death PF00531.22 EST47516.1 - 0.0027 17.8 0.2 0.0058 16.8 0.2 1.4 1 0 0 1 1 1 1 Death domain Peptidase_S49_N PF08496.10 EST47516.1 - 0.075 13.1 1.3 0.15 12.1 1.3 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Baculo_11_kDa PF06143.11 EST47516.1 - 1.1 8.8 8.3 0.16 11.6 2.8 2.4 2 0 0 2 2 2 0 Baculovirus 11 kDa family TMIE PF16038.5 EST47516.1 - 5.3 7.0 10.8 10 6.0 6.7 3.0 2 1 1 3 3 3 0 TMIE protein DnaJ PF00226.31 EST47517.1 - 4.7e-07 29.8 0.1 1e-06 28.7 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain HSCB_C PF07743.13 EST47517.1 - 0.021 15.3 2.5 0.038 14.5 1.7 1.8 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain DUF1199 PF06712.11 EST47518.1 - 2.4 8.2 5.0 1 9.5 1.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1199) MAD PF05557.13 EST47519.1 - 0.024 13.0 7.3 0.053 11.9 7.3 1.5 1 1 0 1 1 1 0 Mitotic checkpoint protein FlaC_arch PF05377.11 EST47519.1 - 0.069 13.6 2.6 0.12 12.8 0.6 2.3 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF3837 PF12939.7 EST47519.1 - 0.23 11.9 2.9 3.4 8.1 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3837) Blo-t-5 PF11642.8 EST47520.1 - 0.18 11.8 4.6 8.6 6.4 0.3 3.2 2 1 0 2 2 2 0 Mite allergen Blo t 5 RRP7 PF12923.7 EST47521.1 - 0.0031 17.7 2.1 0.0044 17.2 2.1 1.2 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_1 PF00076.22 EST47521.1 - 0.0053 16.6 0.0 0.017 14.9 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Plasmid_parti PF01672.16 EST47521.1 - 0.012 16.2 0.8 0.034 14.8 0.6 1.9 1 1 0 1 1 1 0 Putative plasmid partition protein DHH PF01368.20 EST47522.1 - 9.7e-08 32.2 0.0 1.9e-07 31.3 0.0 1.6 1 1 0 1 1 1 1 DHH family CBS PF00571.28 EST47522.1 - 7.7e-07 29.5 0.1 0.024 15.1 0.0 2.8 2 1 0 2 2 2 2 CBS domain DHHA2 PF02833.14 EST47522.1 - 1.4e-05 25.3 0.1 3.5e-05 24.0 0.1 1.7 1 0 0 1 1 1 1 DHHA2 domain Cpn10 PF00166.21 EST47523.1 - 0.11 12.6 0.9 0.23 11.6 0.9 1.6 1 0 0 1 1 1 0 Chaperonin 10 Kd subunit RAP PF08373.10 EST47524.1 - 0.12 12.5 2.2 0.31 11.2 0.2 2.6 3 0 0 3 3 3 0 RAP domain TPR_3 PF07720.12 EST47527.1 - 0.014 15.4 0.2 0.055 13.5 0.2 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-C3HC4_3 PF13920.6 EST47527.1 - 0.22 11.4 0.6 0.51 10.2 0.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4219 PF13961.6 EST47527.1 - 0.9 9.3 2.5 0.59 9.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) CN_hydrolase PF00795.22 EST47529.1 - 7.8e-05 22.1 0.1 0.0075 15.6 0.1 2.1 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase PfkB PF00294.24 EST47534.1 - 1.5e-52 178.8 0.0 1.7e-52 178.6 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EST47534.1 - 0.00025 20.5 0.0 0.00037 19.9 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PcfK PF14058.6 EST47534.1 - 0.17 12.2 1.3 0.2 11.9 0.5 1.5 2 0 0 2 2 2 0 PcfK-like protein TPR_1 PF00515.28 EST47537.1 - 3.7e-10 39.2 9.5 0.00026 20.7 0.4 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 EST47537.1 - 3.7e-09 36.1 9.5 0.35 11.2 0.0 6.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 EST47537.1 - 6.6e-09 35.2 13.0 0.0058 16.6 0.0 7.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 EST47537.1 - 5.2e-08 32.4 3.2 0.062 13.0 0.1 4.5 4 0 0 4 4 4 3 TPR repeat TPR_19 PF14559.6 EST47537.1 - 6e-08 33.1 5.5 0.48 11.0 0.1 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 EST47537.1 - 7.2e-08 32.6 1.4 0.39 11.6 0.2 4.7 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 EST47537.1 - 2.4e-07 31.3 2.1 0.049 14.3 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 EST47537.1 - 8.8e-06 26.0 10.4 1.8 9.4 0.9 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EST47537.1 - 2.9e-05 24.2 5.9 1.5 9.2 0.0 4.6 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 EST47537.1 - 0.01 15.8 7.3 4.7 7.5 0.0 5.2 5 1 0 5 5 5 0 Tetratricopeptide repeat Ntox22 PF15527.6 EST47538.1 - 0.055 13.5 0.5 0.78 9.8 0.0 2.5 3 0 0 3 3 3 0 Bacterial toxin 22 Pho88 PF10032.9 EST47541.1 - 0.056 12.7 2.7 0.11 11.7 2.7 1.5 1 1 0 1 1 1 0 Phosphate transport (Pho88) DnaJ PF00226.31 EST47542.1 - 4.3e-16 58.8 3.3 9.6e-16 57.7 3.3 1.6 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 EST47542.1 - 0.0011 18.8 0.1 0.003 17.4 0.1 1.7 1 0 0 1 1 1 1 A repeated domain in UCH-protein DUF2671 PF10877.8 EST47542.1 - 0.056 13.2 1.6 0.22 11.4 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2671) Ribosomal_L30 PF00327.20 EST47542.1 - 0.064 13.2 0.1 0.16 11.8 0.1 1.7 1 0 0 1 1 1 0 Ribosomal protein L30p/L7e DUF4460 PF14687.6 EST47542.1 - 0.11 12.5 5.2 0.069 13.2 2.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4460) Podoplanin PF05808.11 EST47543.1 - 0.0007 19.7 0.1 0.0014 18.7 0.1 1.5 1 0 0 1 1 1 1 Podoplanin VSP PF03302.13 EST47543.1 - 0.014 14.3 22.1 0.014 14.3 22.1 5.2 1 1 3 4 4 4 0 Giardia variant-specific surface protein Phage_Coat_B PF05356.11 EST47543.1 - 0.071 13.0 0.5 0.17 11.8 0.5 1.7 1 0 0 1 1 1 0 Phage Coat protein B DUF4366 PF14283.6 EST47543.1 - 0.95 9.5 4.3 0.2 11.7 0.2 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) UL2 PF08196.11 EST47544.1 - 0.42 10.6 5.5 0.091 12.7 1.2 2.2 2 0 0 2 2 2 0 UL2 protein NAD_binding_1 PF00175.21 EST47546.1 - 0.079 13.6 2.2 0.086 13.5 2.2 1.1 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain FeoC PF09012.10 EST47546.1 - 0.093 12.8 1.4 0.18 11.9 0.4 1.9 1 1 1 2 2 2 0 FeoC like transcriptional regulator MnmE_helical PF12631.7 EST47546.1 - 0.49 10.5 6.2 0.51 10.5 6.2 1.0 1 0 0 1 1 1 0 MnmE helical domain Pkinase PF00069.25 EST47547.1 - 1.3e-41 142.7 0.0 1.9e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST47547.1 - 1.8e-16 60.2 0.1 2.2e-15 56.7 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EST47547.1 - 0.028 13.8 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EST47547.1 - 0.2 11.5 0.0 0.3 11.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family TagA PF12561.8 EST47548.1 - 4.1 7.9 7.4 2.2 8.7 0.3 4.1 3 2 0 3 3 3 0 ToxR activated gene A lipoprotein domain PsbI PF02532.14 EST47550.1 - 0.14 12.1 0.1 0.33 10.9 0.1 1.6 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) DBD_HTH PF18430.1 EST47551.1 - 0.072 12.9 0.8 0.19 11.5 0.8 1.8 1 1 0 1 1 1 0 Putative DNA-binding domain RcsD_ABL PF16359.5 EST47552.1 - 0.048 13.8 2.7 0.044 13.9 1.5 1.6 1 1 1 2 2 2 0 RcsD-ABL domain Lipase PF00151.19 EST47552.1 - 0.11 11.7 2.4 0.13 11.5 2.4 1.0 1 0 0 1 1 1 0 Lipase DUF2959 PF11172.8 EST47552.1 - 0.18 11.9 5.2 0.21 11.7 5.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) PI31_Prot_C PF08577.11 EST47554.1 - 0.022 15.9 5.8 0.16 13.2 5.8 2.3 1 1 0 1 1 1 0 PI31 proteasome regulator PI31_Prot_C PF08577.11 EST47556.1 - 0.022 15.9 5.8 0.16 13.2 5.8 2.3 1 1 0 1 1 1 0 PI31 proteasome regulator Serinc PF03348.15 EST47557.1 - 1.2e-06 27.8 36.6 1.2e-06 27.8 36.6 3.1 3 1 0 3 3 3 2 Serine incorporator (Serinc) Myb_DNA-binding PF00249.31 EST47558.1 - 5.7e-12 45.6 0.4 1.6e-10 41.0 0.1 2.4 1 1 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST47558.1 - 2e-07 30.8 1.4 2.3e-06 27.4 0.2 2.1 1 1 1 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 EST47558.1 - 3.3e-06 27.3 1.7 3.5e-05 23.9 0.4 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Msap1 PF17077.5 EST47558.1 - 0.00073 18.8 0.0 0.00087 18.6 0.0 1.1 1 0 0 1 1 1 1 Mitotic spindle associated protein SHE1 SANT_DAMP1_like PF16282.5 EST47558.1 - 0.0067 16.6 0.9 0.014 15.6 0.8 1.7 1 1 0 1 1 1 1 SANT/Myb-like domain of DAMP1 partial_CstF PF15861.5 EST47558.1 - 0.044 13.6 0.2 0.16 11.8 0.2 2.0 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain Rubrerythrin PF02915.17 EST47563.1 - 9.9e-26 90.8 0.3 1.3e-25 90.4 0.3 1.2 1 0 0 1 1 1 1 Rubrerythrin Ferritin PF00210.24 EST47563.1 - 3.4e-08 33.5 0.5 4.2e-07 30.0 0.5 2.0 1 1 0 1 1 1 1 Ferritin-like domain zf-UBP PF02148.19 EST47563.1 - 0.021 15.1 0.5 0.077 13.3 0.1 2.0 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein HalOD2 PF18547.1 EST47563.1 - 0.041 13.8 4.0 0.045 13.7 1.9 2.0 1 1 1 2 2 2 0 Halobacterial output domain 2 DUF3039 PF11238.8 EST47563.1 - 0.049 13.4 0.4 0.097 12.4 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3039) zinc_ribbon_11 PF11682.8 EST47563.1 - 0.053 13.5 0.0 0.074 13.1 0.0 1.3 1 0 0 1 1 1 0 Probable zinc-ribbon Vps36-NZF-N PF16988.5 EST47563.1 - 0.15 11.5 1.2 1.9 7.9 0.4 2.4 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 EST47563.1 - 0.22 11.6 2.7 1.7 8.7 0.4 2.3 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger OrfB_Zn_ribbon PF07282.11 EST47563.1 - 0.3 11.0 2.2 0.3 11.0 0.3 1.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Prim_Zn_Ribbon PF08273.12 EST47563.1 - 0.61 10.4 2.7 2.6 8.4 0.1 2.6 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase EcsB PF05975.12 EST47565.1 - 0.0037 16.2 0.2 0.0051 15.7 0.2 1.3 1 0 0 1 1 1 1 Bacterial ABC transporter protein EcsB CytochromB561_N PF09786.9 EST47565.1 - 0.02 14.0 0.2 0.024 13.6 0.2 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF3094 PF11293.8 EST47565.1 - 0.076 12.7 0.2 0.22 11.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) LRR_6 PF13516.6 EST47566.1 - 0.004 17.1 0.8 44 4.5 0.0 5.0 5 0 0 5 5 5 2 Leucine Rich repeat SWIRM PF04433.17 EST47567.1 - 3e-06 27.5 0.0 3.7e-05 24.0 0.0 2.8 3 0 0 3 3 3 1 SWIRM domain RRP36 PF06102.12 EST47567.1 - 0.064 13.2 0.3 0.13 12.2 0.3 1.4 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 PYC_OADA PF02436.18 EST47568.1 - 7.9e-47 159.6 2.5 1.6e-46 158.6 2.5 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain HMGL-like PF00682.19 EST47568.1 - 3.2e-20 72.8 0.0 9.1e-20 71.3 0.0 1.7 1 1 0 1 1 1 1 HMGL-like Carboxyl_trans PF01039.22 EST47568.1 - 1.3e-11 43.9 0.1 1.3e-05 24.1 0.0 2.2 2 0 0 2 2 2 2 Carboxyl transferase domain Biotin_lipoyl PF00364.22 EST47568.1 - 2.1e-07 30.7 0.2 7.4e-07 28.9 0.2 2.0 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EST47568.1 - 0.072 12.9 2.7 9.2 6.2 0.0 3.6 2 1 1 3 3 3 0 Biotin-lipoyl like HlyD_D23 PF16576.5 EST47568.1 - 0.14 11.3 0.9 2.1 7.5 0.1 2.6 2 1 1 3 3 3 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl PF00364.22 EST47569.1 - 1.7e-08 34.1 0.1 1.9e-08 34.0 0.1 1.0 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EST47569.1 - 0.013 15.3 0.1 0.11 12.3 0.0 2.0 1 1 1 2 2 2 0 Biotin-lipoyl like HlyD_D23 PF16576.5 EST47569.1 - 0.016 14.4 0.0 1.4 8.1 0.0 2.0 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion RRP36 PF06102.12 EST47570.1 - 0.04 13.9 0.3 0.071 13.1 0.3 1.3 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 SWIRM PF04433.17 EST47571.1 - 2e-06 28.0 0.0 8.8e-06 26.0 0.0 2.0 2 0 0 2 2 2 1 SWIRM domain LRR_6 PF13516.6 EST47572.1 - 0.0029 17.5 0.8 42 4.6 0.0 5.2 5 0 0 5 5 5 2 Leucine Rich repeat Insulin_TMD PF17870.1 EST47573.1 - 0.0026 17.8 0.2 0.0087 16.1 0.2 1.9 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment CytochromB561_N PF09786.9 EST47573.1 - 0.0085 15.1 0.3 0.01 14.9 0.3 1.1 1 0 0 1 1 1 1 Cytochrome B561, N terminal DUF3094 PF11293.8 EST47573.1 - 0.061 13.1 0.2 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) Lipase_GDSL_lke PF16255.5 EST47573.1 - 0.086 12.2 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase DUF4307 PF14155.6 EST47573.1 - 0.15 11.9 1.5 1.2 9.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) FeoB_associated PF12669.7 EST47573.1 - 0.56 10.7 1.7 1.1 9.7 1.7 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Pribosyltran PF00156.27 EST47575.1 - 2.9e-12 46.4 0.1 3.8e-12 46.0 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EST47575.1 - 0.019 14.4 0.0 0.023 14.1 0.0 1.1 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase F420_ligase PF01996.16 EST47576.1 - 3.7e-76 255.7 0.0 4.2e-76 255.5 0.0 1.0 1 0 0 1 1 1 1 F420-0:Gamma-glutamyl ligase Rad60-SLD PF11976.8 EST47577.1 - 8.7e-08 31.9 0.3 3e-07 30.2 0.3 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407_C PF13373.6 EST47577.1 - 6.7e-06 26.3 0.1 0.00025 21.2 0.0 2.7 3 0 0 3 3 3 1 DUF2407 C-terminal domain ubiquitin PF00240.23 EST47577.1 - 0.0022 17.7 1.4 0.0035 17.1 0.2 1.9 2 0 0 2 2 2 1 Ubiquitin family CAP PF00188.26 EST47579.1 - 0.003 18.4 0.0 0.0051 17.6 0.0 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Podoplanin PF05808.11 EST47579.1 - 0.041 14.0 1.6 0.066 13.3 1.6 1.2 1 0 0 1 1 1 0 Podoplanin VSP PF03302.13 EST47579.1 - 0.16 10.8 1.3 0.23 10.3 1.3 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein Metallophos PF00149.28 EST47580.1 - 4.3e-09 37.2 8.7 1.6e-08 35.3 3.5 2.4 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase B12-binding PF02310.19 EST47580.1 - 0.23 11.5 0.0 0.5 10.4 0.0 1.5 1 0 0 1 1 1 0 B12 binding domain DUF3958 PF13125.6 EST47582.1 - 0.16 12.2 0.1 0.16 12.2 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3958) DUF5339 PF17274.2 EST47582.1 - 4.1 8.3 7.2 1 10.3 2.8 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5339) zf-C3HC4_4 PF15227.6 EST47583.1 - 1.1e-10 41.5 11.9 1.9e-10 40.7 11.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EST47583.1 - 2.6e-09 36.9 5.6 2.6e-09 36.9 5.6 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EST47583.1 - 1.1e-08 34.8 9.9 1.8e-08 34.1 9.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EST47583.1 - 1.3e-08 34.6 10.7 1.8e-08 34.1 10.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EST47583.1 - 2.6e-08 33.6 11.2 4.2e-08 32.9 11.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EST47583.1 - 3.9e-07 30.3 10.2 6.3e-07 29.6 10.2 1.3 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EST47583.1 - 2.1e-06 27.5 15.4 9.5e-05 22.2 15.9 2.2 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EST47583.1 - 0.00031 20.7 13.5 0.0045 16.9 14.5 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 EST47583.1 - 0.001 18.9 4.3 0.0017 18.2 4.3 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-MIZ PF02891.20 EST47583.1 - 0.0036 17.0 9.7 0.0054 16.5 8.9 1.8 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger U-box PF04564.15 EST47583.1 - 0.0093 16.1 0.4 0.027 14.7 0.0 1.9 3 0 0 3 3 3 1 U-box domain Rad50_zn_hook PF04423.14 EST47583.1 - 0.023 14.5 0.3 0.023 14.5 0.3 2.4 3 0 0 3 3 2 0 Rad50 zinc hook motif Rtf2 PF04641.12 EST47583.1 - 0.18 11.1 2.1 0.23 10.8 2.1 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger zf-Di19 PF05605.12 EST47583.1 - 2.2 8.6 9.8 7.8 6.9 9.8 1.8 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Elf1 PF05129.13 EST47583.1 - 3.1 7.9 8.4 6.4 6.9 4.0 2.3 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-RING_4 PF14570.6 EST47583.1 - 3.3 7.6 10.5 18 5.2 10.8 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain PQ-loop PF04193.14 EST47584.1 - 2e-21 75.5 13.4 5e-13 48.6 1.8 3.4 4 0 0 4 4 4 2 PQ loop repeat Chordopox_A13L PF05961.11 EST47584.1 - 0.02 15.1 2.4 1.6 9.0 1.4 2.6 2 0 0 2 2 2 0 Chordopoxvirus A13L protein DUF3958 PF13125.6 EST47585.1 - 0.16 12.2 0.1 0.16 12.2 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3958) DUF5339 PF17274.2 EST47585.1 - 4.1 8.3 7.2 1 10.3 2.8 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5339) PhetRS_B1 PF18262.1 EST47587.1 - 3.4e-28 97.7 0.0 8.3e-28 96.4 0.0 1.7 1 0 0 1 1 1 1 Phe-tRNA synthetase beta subunit B1 domain tRNA_synthFbeta PF17759.1 EST47587.1 - 1.4e-27 96.6 0.0 3.9e-27 95.1 0.0 1.8 3 0 0 3 3 3 1 Phenylalanyl tRNA synthetase beta chain CLM domain B3_4 PF03483.17 EST47587.1 - 6.1e-21 74.9 0.2 1.2e-20 73.8 0.2 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 EST47587.1 - 2.5e-20 72.5 0.0 1.8e-14 53.7 0.0 2.7 2 0 0 2 2 2 2 tRNA synthetase B5 domain DUF2067 PF09840.9 EST47587.1 - 0.13 11.8 0.8 0.59 9.7 0.0 2.5 3 1 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2067) ubiquitin PF00240.23 EST47588.1 - 1.8e-33 114.1 0.6 2.3e-33 113.7 0.6 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EST47588.1 - 3.6e-18 65.1 0.9 6e-18 64.4 0.9 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ribosomal_L40e PF01020.17 EST47588.1 - 4.8e-17 61.6 5.4 7.6e-17 60.9 5.4 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Ubiquitin_2 PF14560.6 EST47588.1 - 2.6e-05 24.6 0.2 9.9e-05 22.7 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EST47588.1 - 0.00014 22.0 0.1 0.00025 21.1 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EST47588.1 - 0.00079 19.9 0.1 0.00083 19.9 0.1 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain TBK1_ULD PF18396.1 EST47588.1 - 0.0011 18.8 0.1 0.0018 18.2 0.1 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EST47588.1 - 0.0034 17.7 0.1 0.005 17.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 EST47588.1 - 0.0039 17.2 0.8 1.9 8.6 0.1 2.2 1 1 1 2 2 2 2 Ubiquitin-like domain Gamma_PGA_hydro PF05908.11 EST47588.1 - 0.074 12.4 0.0 0.097 12.1 0.0 1.1 1 0 0 1 1 1 0 Poly-gamma-glutamate hydrolase Sde2_N_Ubi PF13019.6 EST47588.1 - 0.082 12.7 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain QueC PF06508.13 EST47588.1 - 0.1 12.1 0.2 0.14 11.6 0.2 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Ribosomal_L29 PF00831.23 EST47589.1 - 8.2e-14 51.3 2.5 8.2e-14 51.3 2.5 1.9 1 1 1 2 2 2 1 Ribosomal L29 protein DUF1722 PF08349.11 EST47589.1 - 0.016 15.4 2.4 0.081 13.2 2.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1722) RAC_head PF16717.5 EST47589.1 - 0.026 15.5 4.4 0.038 15.0 0.2 2.1 1 1 0 2 2 2 0 Ribosome-associated complex head domain Eno-Rase_FAD_bd PF07055.12 EST47589.1 - 0.04 14.3 0.8 3.8 8.0 0.1 2.2 2 0 0 2 2 2 0 Enoyl reductase FAD binding domain HI0933_like PF03486.14 EST47589.1 - 0.21 10.2 2.7 0.25 10.0 2.7 1.1 1 0 0 1 1 1 0 HI0933-like protein gpUL132 PF11359.8 EST47590.1 - 0.0012 18.5 0.7 0.0018 17.9 0.7 1.3 1 0 0 1 1 1 1 Glycoprotein UL132 CLP1_N PF16573.5 EST47591.1 - 0.092 13.0 0.1 0.48 10.7 0.0 2.2 2 0 0 2 2 2 0 N-terminal beta-sandwich domain of polyadenylation factor Beach PF02138.18 EST47592.1 - 9.4e-35 120.3 10.0 3.8e-34 118.3 10.0 1.9 1 1 0 1 1 1 1 Beige/BEACH domain EssA PF10661.9 EST47592.1 - 0.019 14.8 0.4 0.059 13.2 0.4 1.8 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA SapB_1 PF05184.15 EST47592.1 - 0.16 12.0 0.5 0.34 11.0 0.5 1.6 1 0 0 1 1 1 0 Saposin-like type B, region 1 PGI PF00342.19 EST47593.1 - 1.8e-50 171.9 0.0 1e-48 166.1 0.0 2.0 1 1 0 1 1 1 1 Phosphoglucose isomerase Mobilization_B PF17511.2 EST47594.1 - 0.35 11.3 2.7 1.7 9.0 2.7 2.2 1 0 0 1 1 1 0 Mobilization protein B TPR_2 PF07719.17 EST47595.1 - 0.00089 19.2 3.3 0.28 11.4 0.1 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 EST47595.1 - 0.028 14.3 0.3 0.028 14.3 0.3 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EST47595.1 - 0.14 12.5 5.5 22 5.6 0.3 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat MatE PF01554.18 EST47596.1 - 5.3e-05 22.9 12.6 5.3e-05 22.9 12.6 3.7 4 0 0 4 4 4 2 MatE TMF_DNA_bd PF12329.8 EST47597.1 - 1.1e-05 25.4 6.9 1.7e-05 24.7 6.9 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding Paramyx_P_V_C PF03210.13 EST47597.1 - 0.013 15.3 0.3 0.015 15.1 0.3 1.1 1 0 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal DUF553 PF04473.12 EST47597.1 - 0.014 15.0 0.6 0.017 14.6 0.6 1.1 1 0 0 1 1 1 0 Transglutaminase-like domain ATG16 PF08614.11 EST47597.1 - 0.021 15.1 7.1 0.039 14.2 7.1 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF724 PF05266.14 EST47597.1 - 0.076 12.8 1.9 0.09 12.6 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DivIC PF04977.15 EST47597.1 - 1 9.2 7.0 1.8 8.4 6.6 1.9 1 1 0 1 1 1 0 Septum formation initiator PP_kinase_N PF13089.6 EST47598.1 - 0.26 11.6 3.8 1.7 9.0 3.1 2.2 1 1 1 2 2 2 0 Polyphosphate kinase N-terminal domain dUTPase PF00692.19 EST47599.1 - 4.4e-26 91.1 0.1 5.5e-26 90.8 0.1 1.0 1 0 0 1 1 1 1 dUTPase ASH PF15780.5 EST47600.1 - 3.6e-13 49.5 11.8 0.021 15.0 0.0 9.6 12 0 0 12 12 12 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 EST47600.1 - 1.9e-08 34.2 7.6 0.019 15.0 0.0 7.8 9 0 0 9 9 9 1 Protein of unknown function (DUF1573) Motile_Sperm PF00635.26 EST47600.1 - 5.7e-05 22.9 11.1 0.00044 20.1 0.0 6.9 8 0 0 8 8 8 1 MSP (Major sperm protein) domain PapD-like PF14874.6 EST47600.1 - 0.0029 17.7 0.8 1.2e+02 2.9 0.0 5.7 6 0 0 6 6 6 0 Flagellar-associated PapD-like MYCBPAP PF14646.6 EST47600.1 - 0.011 14.7 0.9 4.8 6.0 0.0 3.1 3 1 0 3 3 3 0 MYCBP-associated protein family FixG_C PF11614.8 EST47600.1 - 2.4 8.4 5.7 5.9 7.1 0.1 4.1 5 0 0 5 5 5 0 IG-like fold at C-terminal of FixG, putative oxidoreductase T6PP_N PF18572.1 EST47601.1 - 2 8.3 9.4 8.8 6.2 0.8 3.7 3 0 0 3 3 3 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain DUF16 PF01519.16 EST47601.1 - 7.4 7.1 14.8 0.42 11.1 5.8 2.9 1 1 1 2 2 2 0 Protein of unknown function DUF16 Ank_2 PF12796.7 EST47602.1 - 0.0031 18.0 0.0 0.082 13.5 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) HSP70 PF00012.20 EST47603.1 - 4.1e-46 157.4 0.9 4.1e-46 157.4 0.9 3.8 3 1 1 4 4 4 1 Hsp70 protein CPDase PF07823.11 EST47603.1 - 0.31 10.7 2.1 12 5.5 0.1 2.8 2 1 0 2 2 2 0 Cyclic phosphodiesterase-like protein DEAD PF00270.29 EST47605.1 - 4.1e-33 114.6 0.1 4.1e-33 114.6 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EST47605.1 - 1.5e-22 80.1 0.6 7e-21 74.6 0.1 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EST47605.1 - 0.0074 16.6 0.4 0.21 11.9 0.4 2.8 1 1 0 1 1 1 1 AAA domain MutL_C PF08676.11 EST47606.1 - 4.4e-20 72.0 2.3 4.8e-20 71.8 0.5 1.9 2 0 0 2 2 2 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 EST47606.1 - 2.3e-11 43.4 0.2 6.8e-11 41.9 0.2 1.8 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 EST47606.1 - 9.7e-08 32.5 0.2 4.8e-07 30.3 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EST47606.1 - 2.4e-07 30.7 0.0 9.6e-07 28.7 0.0 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PPTA PF01239.22 EST47607.1 - 1e-14 53.6 12.9 5.6e-07 29.1 0.3 5.8 6 0 0 6 6 6 4 Protein prenyltransferase alpha subunit repeat SNARE PF05739.19 EST47608.1 - 2.1e-08 34.0 1.5 6.1e-08 32.5 1.5 1.9 1 0 0 1 1 1 1 SNARE domain Ric8 PF10165.9 EST47608.1 - 0.076 12.0 5.6 0.085 11.9 5.6 1.2 1 0 0 1 1 1 0 Guanine nucleotide exchange factor synembryn Methuselah_N PF06652.12 EST47608.1 - 0.36 10.7 4.0 0.14 12.0 0.5 1.9 1 1 2 3 3 3 0 Methuselah N-terminus MCPsignal PF00015.21 EST47608.1 - 0.66 9.8 8.5 0.11 12.4 3.1 2.2 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 EST47608.1 - 4.7 7.5 7.5 2.4 8.5 0.3 3.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) SNARE PF05739.19 EST47609.1 - 4e-06 26.7 0.9 7.5e-06 25.9 0.9 1.5 1 0 0 1 1 1 1 SNARE domain DDHD PF02862.17 EST47609.1 - 0.011 15.9 4.0 0.016 15.4 4.0 1.2 1 0 0 1 1 1 0 DDHD domain Mod_r PF07200.13 EST47609.1 - 0.084 13.0 13.0 0.36 10.9 2.9 2.2 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein HsbA PF12296.8 EST47609.1 - 0.21 12.0 12.4 7.3 7.0 0.1 3.0 2 1 1 3 3 3 0 Hydrophobic surface binding protein A COG2 PF06148.11 EST47609.1 - 0.36 10.9 7.6 1.1 9.3 0.2 2.7 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF745 PF05335.13 EST47609.1 - 9.8 5.9 12.4 0.45 10.2 4.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF745) NAC PF01849.18 EST47610.1 - 3.9e-05 23.5 0.1 8.2e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 NAC domain HOIP-UBA PF16678.5 EST47610.1 - 0.0014 18.6 0.1 0.002 18.2 0.1 1.3 1 0 0 1 1 1 1 HOIP UBA domain pair Cohesin PF00963.18 EST47612.1 - 0.021 15.1 1.6 0.03 14.6 1.6 1.2 1 0 0 1 1 1 0 Cohesin domain fn3_6 PF17766.1 EST47612.1 - 0.028 14.6 0.4 0.042 14.0 0.4 1.4 1 0 0 1 1 1 0 Fibronectin type-III domain BACON PF13004.7 EST47612.1 - 0.053 13.5 0.4 0.095 12.7 0.4 1.5 1 0 0 1 1 1 0 Putative binding domain, N-terminal ABC_transp_aux PF09822.9 EST47614.1 - 0.012 15.1 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 ABC-type uncharacterized transport system DUF4451 PF14616.6 EST47614.1 - 0.054 13.7 0.1 0.096 12.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) PUF PF00806.19 EST47617.1 - 7.3e-13 47.4 13.4 0.00078 19.0 0.2 5.7 6 0 0 6 6 6 4 Pumilio-family RNA binding repeat DUF4806 PF16064.5 EST47619.1 - 1.1 9.5 8.7 0.56 10.5 0.1 4.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4806) S4 PF01479.25 EST47621.1 - 1.1e-10 41.0 0.8 2.3e-10 40.0 0.0 1.9 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 EST47621.1 - 0.0017 19.3 1.6 0.0023 18.8 1.0 1.6 1 1 1 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain SURF6 PF04935.12 EST47622.1 - 4.8e-08 33.1 37.1 6.7e-08 32.6 37.1 1.3 1 0 0 1 1 1 1 Surfeit locus protein 6 Thioredoxin_6 PF13848.6 EST47624.1 - 0.0033 17.3 3.2 0.0043 17.0 0.2 2.2 1 1 1 2 2 2 1 Thioredoxin-like domain DHHC PF01529.20 EST47626.1 - 4.2e-09 36.6 3.5 4.2e-09 36.6 3.5 3.2 2 1 1 3 3 3 1 DHHC palmitoyltransferase TFIIS_M PF07500.14 EST47626.1 - 0.065 13.7 2.7 0.15 12.6 0.5 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS), central domain Sybindin PF04099.12 EST47628.1 - 1.9e-11 44.1 2.6 6.9e-11 42.3 2.6 1.7 1 1 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 EST47628.1 - 0.00087 19.4 0.8 0.0014 18.8 0.8 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Pkinase_Tyr PF07714.17 EST47629.1 - 2.6e-05 23.7 0.5 2.6e-05 23.7 0.5 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase UPF0223 PF05256.12 EST47629.1 - 0.041 14.2 1.3 0.041 14.2 1.3 3.3 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0223) AAA_11 PF13086.6 EST47630.1 - 5.2e-19 69.0 0.3 2.7e-08 33.9 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_12 PF13087.6 EST47630.1 - 4.2e-18 65.7 1.0 4.2e-18 65.7 1.0 2.9 3 2 0 3 3 3 1 AAA domain AAA_30 PF13604.6 EST47630.1 - 1.5e-08 34.6 0.0 0.011 15.4 0.0 3.2 3 1 0 3 3 3 2 AAA domain AAA_19 PF13245.6 EST47630.1 - 2.4e-08 34.4 0.4 4.3e-07 30.4 0.1 2.9 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 EST47630.1 - 3.8e-06 26.8 0.0 0.00034 20.4 0.0 2.9 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 EST47630.1 - 0.00018 21.8 0.4 0.085 13.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain PhoH PF02562.16 EST47630.1 - 0.0053 16.2 0.0 0.017 14.6 0.0 1.9 1 0 0 1 1 1 1 PhoH-like protein AAA PF00004.29 EST47630.1 - 0.0087 16.5 0.0 0.14 12.6 0.0 2.8 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 EST47630.1 - 0.011 15.7 2.1 0.17 11.9 2.1 2.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Epimerase_2 PF02350.19 EST47630.1 - 0.045 12.6 0.1 1.1 8.1 0.0 2.2 2 0 0 2 2 2 0 UDP-N-acetylglucosamine 2-epimerase RNA_helicase PF00910.22 EST47630.1 - 0.068 13.6 0.0 0.32 11.4 0.0 2.2 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 EST47630.1 - 0.089 13.2 0.0 0.26 11.7 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 EST47630.1 - 0.11 12.4 0.0 0.88 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EST47630.1 - 0.12 12.1 0.1 0.99 9.1 0.0 2.2 1 1 1 2 2 2 0 AAA domain UvrD_C_2 PF13538.6 EST47630.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_33 PF13671.6 EST47630.1 - 0.16 12.1 0.0 0.5 10.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain Profilin PF00235.19 EST47631.1 - 1.1e-05 25.7 0.0 1.4e-05 25.3 0.0 1.3 1 1 0 1 1 1 1 Profilin Myb_DNA-bind_6 PF13921.6 EST47632.1 - 1.2e-10 41.4 7.2 3.3e-10 40.1 3.1 2.4 1 1 2 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EST47632.1 - 1.3e-08 34.9 3.1 0.00011 22.3 0.0 2.9 3 1 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EST47632.1 - 0.00011 22.6 2.8 0.0044 17.4 0.5 2.3 1 1 1 2 2 2 2 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 EST47633.1 - 5.8e-16 58.4 2.9 4.5e-09 36.4 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST47633.1 - 2.3e-13 50.2 4.5 6.5e-12 45.5 2.0 1.9 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 EST47633.1 - 0.00037 20.5 0.5 0.46 10.6 0.1 2.2 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 EST47633.1 - 0.0026 17.6 0.4 0.0083 16.0 0.0 1.9 2 0 0 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 EST47633.1 - 0.035 14.1 0.3 0.33 11.0 0.1 2.2 1 1 1 2 2 2 0 SLIDE Myb_DNA-bind_4 PF13837.6 EST47633.1 - 0.062 13.7 6.2 0.45 10.9 1.3 2.8 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain OrfB_IS605 PF01385.19 EST47633.1 - 0.085 13.1 0.1 0.17 12.1 0.0 1.5 2 0 0 2 2 2 0 Probable transposase MMtag PF10159.9 EST47634.1 - 1.1 9.6 3.0 1.2 9.5 0.1 2.3 2 0 0 2 2 2 0 Multiple myeloma tumor-associated Tiam_CC_Ex PF18385.1 EST47634.1 - 1.3 9.5 8.0 2.4 8.6 2.1 2.8 2 1 1 3 3 3 0 T-lymphoma invasion and metastasis CC-Ex domain Ufm1 PF03671.14 EST47635.1 - 0.00048 20.1 0.0 0.00075 19.5 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin fold modifier 1 protein Coatomer_WDAD PF04053.14 EST47636.1 - 0.00015 20.9 10.7 2.3 7.1 0.0 5.8 5 1 0 6 6 6 3 Coatomer WD associated region CttA_N PF18244.1 EST47636.1 - 0.042 14.3 0.1 0.13 12.7 0.1 1.8 1 0 0 1 1 1 0 Cellulose-binding protein CttA N-terminal domain TPR_2 PF07719.17 EST47636.1 - 0.073 13.2 0.2 19 5.7 0.0 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat ANAPC4_WD40 PF12894.7 EST47636.1 - 0.08 13.2 4.8 5.7 7.3 0.1 4.5 3 1 2 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain TPR_14 PF13428.6 EST47636.1 - 8.4 7.5 7.6 1.2e+02 3.9 0.4 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat PhnA_Zn_Ribbon PF08274.12 EST47636.1 - 8.7 6.4 5.9 2.8 8.0 1.2 2.3 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Fib_alpha PF08702.10 EST47638.1 - 3.6 7.8 9.5 1.8 8.7 2.5 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family JHY PF15261.6 EST47639.1 - 4.6e-17 63.0 11.6 5.8e-17 62.6 11.6 1.1 1 0 0 1 1 1 1 Jhy protein MyTH4 PF00784.17 EST47639.1 - 0.059 13.9 0.7 0.093 13.2 0.2 1.6 2 0 0 2 2 2 0 MyTH4 domain Ndc1_Nup PF09531.10 EST47639.1 - 0.52 8.9 3.7 0.61 8.7 3.7 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Prefoldin PF02996.17 EST47642.1 - 3.6e-24 85.0 0.1 4.5e-24 84.7 0.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 EST47642.1 - 0.00061 19.7 3.4 0.00069 19.5 0.3 2.0 2 0 0 2 2 2 1 Prefoldin subunit CCDC92 PF14916.6 EST47642.1 - 0.03 14.1 0.1 0.075 12.8 0.1 1.7 1 0 0 1 1 1 0 Coiled-coil domain of unknown function USP8_interact PF08941.10 EST47642.1 - 0.089 12.6 0.5 1.3 8.8 0.2 2.1 2 0 0 2 2 2 0 USP8 interacting POR_N PF01855.19 EST47643.1 - 8e-62 209.0 0.6 1.8e-61 207.8 0.6 1.6 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 EST47643.1 - 7.9e-16 58.6 0.4 1.4e-15 57.9 0.4 1.4 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 EST47643.1 - 1.5e-13 50.9 0.2 4.8e-13 49.3 0.2 2.0 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Fer4_7 PF12838.7 EST47643.1 - 4.2e-07 30.5 9.9 1.8e-06 28.5 9.5 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Transketolase_C PF02780.20 EST47643.1 - 8.9e-07 28.8 0.1 3.1e-06 27.1 0.1 1.9 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.21 EST47643.1 - 1.7e-06 27.9 0.2 6.5e-06 26.0 0.1 2.2 2 0 0 2 2 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4_21 PF14697.6 EST47643.1 - 4.1e-06 26.8 13.9 5.1e-05 23.3 13.9 2.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EST47643.1 - 8.7e-06 26.6 11.5 0.018 15.9 5.5 2.9 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4 PF00037.27 EST47643.1 - 1e-05 25.1 12.5 0.022 14.5 6.1 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 EST47643.1 - 1.1e-05 25.2 12.5 0.0088 16.1 1.9 2.9 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 EST47643.1 - 1.7e-05 24.7 14.3 0.0015 18.5 1.2 2.9 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 EST47643.1 - 5.2e-05 23.3 7.4 0.024 14.7 3.0 2.7 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 EST47643.1 - 0.00021 21.7 7.5 0.00021 21.7 7.5 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EST47643.1 - 0.0018 18.4 17.6 0.0031 17.7 14.3 2.7 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_8 PF13183.6 EST47643.1 - 0.007 16.8 10.6 0.0084 16.5 8.8 2.2 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.6 EST47643.1 - 0.047 13.9 5.5 0.57 10.4 0.5 2.7 2 0 0 2 2 2 0 4Fe-4S dicluster domain EKR PF10371.9 EST47643.1 - 0.058 13.2 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function Fer4_4 PF12800.7 EST47643.1 - 0.068 13.7 14.0 1.3 9.7 5.0 3.0 2 0 0 2 2 2 0 4Fe-4S binding domain DUF1500 PF07389.12 EST47643.1 - 0.13 12.4 0.2 3.1 7.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1500) Fer4_15 PF13459.6 EST47643.1 - 0.4 11.5 2.7 4.2 8.2 0.4 2.8 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_22 PF17179.4 EST47643.1 - 0.52 11.2 7.8 1.5 9.7 1.1 3.0 2 0 0 2 2 2 0 4Fe-4S dicluster domain ETF_QO PF05187.13 EST47643.1 - 4.6 7.4 5.9 2 8.6 0.1 2.9 3 0 0 3 3 3 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_13 PF13370.6 EST47643.1 - 9 6.9 12.0 6.6 7.4 0.9 2.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Transp_Tc5_C PF04236.15 EST47645.1 - 0.041 14.2 3.4 0.085 13.2 3.4 1.5 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain Sas6_CC PF18594.1 EST47646.1 - 0.26 11.1 0.2 0.26 11.1 0.2 2.4 2 0 0 2 2 2 0 Sas6/XLF/XRCC4 coiled-coil domain Ribosomal_L11 PF00298.19 EST47647.1 - 0.1 13.1 0.0 0.35 11.4 0.0 1.9 1 0 0 1 1 1 0 Ribosomal protein L11, RNA binding domain JTB PF05439.12 EST47648.1 - 0.026 14.6 14.1 0.16 12.0 1.9 2.4 1 1 1 2 2 2 0 Jumping translocation breakpoint protein (JTB) A2L_zn_ribbon PF08792.10 EST47648.1 - 0.61 9.9 22.7 0.4 10.4 6.6 4.7 3 2 1 4 4 4 0 A2L zinc ribbon domain Ephrin_rec_like PF07699.13 EST47648.1 - 1.2 8.9 15.5 0.11 12.2 3.5 2.8 2 1 0 2 2 2 0 Putative ephrin-receptor like Proteasome PF00227.26 EST47651.1 - 8.4e-27 93.9 0.1 9.7e-27 93.7 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit PMBR PF09373.10 EST47651.1 - 0.1 12.8 0.1 0.29 11.4 0.1 1.9 1 0 0 1 1 1 0 Pseudomurein-binding repeat MurJ PF03023.14 EST47651.1 - 0.13 10.8 0.0 0.18 10.3 0.0 1.2 1 0 0 1 1 1 0 Lipid II flippase MurJ DUF4612 PF15389.6 EST47652.1 - 0.032 15.3 0.4 0.058 14.4 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4612) DUF4891 PF16232.5 EST47653.1 - 0.085 13.4 0.2 0.17 12.5 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4891) FERM_f0 PF16511.5 EST47653.1 - 0.097 13.0 1.1 0.27 11.6 0.2 2.0 1 1 1 2 2 2 0 N-terminal or F0 domain of Talin-head FERM CLU PF13236.6 EST47654.1 - 1.4e-06 28.3 7.9 9.5e-05 22.3 1.3 2.6 2 0 0 2 2 2 2 Clustered mitochondria DUF4447 PF14590.6 EST47654.1 - 0.096 12.5 1.1 0.25 11.1 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4447) HAD_2 PF13419.6 EST47655.1 - 1.1e-23 84.2 0.1 1.5e-23 83.8 0.1 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EST47655.1 - 6.2e-11 43.0 0.0 1.7e-09 38.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EST47655.1 - 4.4e-05 24.0 0.0 7.5e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EST47655.1 - 0.1 12.7 0.1 1.2 9.3 0.1 2.7 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EST47655.1 - 0.16 12.0 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 HAD-hyrolase-like CemA PF03040.14 EST47656.1 - 0.058 13.3 2.9 0.076 12.9 2.9 1.2 1 0 0 1 1 1 0 CemA family TM2 PF05154.16 EST47659.1 - 5.3e-08 33.1 14.4 7.1e-08 32.7 14.4 1.2 1 0 0 1 1 1 1 TM2 domain BMFP PF04380.13 EST47660.1 - 0.011 16.3 0.4 0.011 16.3 0.4 2.4 3 0 0 3 3 3 0 Membrane fusogenic activity RNA_pol_Rpb2_1 PF04563.15 EST47660.1 - 0.11 12.0 1.6 0.26 10.8 1.6 1.6 1 0 0 1 1 1 0 RNA polymerase beta subunit RtcB PF01139.17 EST47663.1 - 4.9e-19 68.8 0.1 2.1e-16 60.1 0.0 2.7 2 2 0 2 2 2 2 tRNA-splicing ligase RtcB AMP-binding PF00501.28 EST47664.1 - 1e-75 254.9 0.0 5.4e-55 186.7 0.0 2.3 2 1 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 EST47664.1 - 0.014 16.3 0.0 0.038 15.0 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Rota_NS53 PF00981.17 EST47665.1 - 0.013 14.4 2.9 0.014 14.3 2.9 1.2 1 0 0 1 1 1 0 Rotavirus RNA-binding Protein 53 (NS53) Seadorna_VP6 PF07407.11 EST47665.1 - 0.15 11.0 1.3 0.2 10.6 0.2 1.7 2 0 0 2 2 2 0 Seadornavirus VP6 protein DivIC PF04977.15 EST47665.1 - 1.4 8.7 12.1 0.17 11.6 1.5 2.8 3 0 0 3 3 3 0 Septum formation initiator TSC22 PF01166.18 EST47665.1 - 6.1 7.2 8.5 2.2 8.6 1.1 3.1 3 0 0 3 3 3 0 TSC-22/dip/bun family PTPA PF03095.15 EST47666.1 - 1.2e-76 258.0 2.8 1.4e-76 257.9 2.8 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein WD40_like PF17005.5 EST47668.1 - 4.5e-05 22.9 2.2 6.3e-05 22.5 1.9 1.4 1 1 0 1 1 1 1 WD40-like domain UCH PF00443.29 EST47669.1 - 2.1e-27 96.2 0.0 1.7e-24 86.8 0.0 3.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EST47669.1 - 0.0019 17.9 1.4 0.0019 17.9 1.4 2.9 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Josephin PF02099.17 EST47669.1 - 0.054 13.6 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Josephin YacG PF03884.14 EST47669.1 - 0.13 12.0 2.2 1.2 8.9 0.2 2.5 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG TPR_12 PF13424.6 EST47670.1 - 0.038 14.3 7.1 3.4 8.0 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Kazal_2 PF07648.15 EST47670.1 - 0.077 13.1 0.2 0.2 11.8 0.1 1.7 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain TPR_2 PF07719.17 EST47670.1 - 0.098 12.8 2.2 0.59 10.4 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EST47670.1 - 0.2 11.6 2.2 0.37 10.7 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EST47670.1 - 2.8 8.6 8.9 0.49 11.1 1.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Trypan_PARP PF05887.11 EST47671.1 - 0.00069 19.6 9.7 0.00069 19.6 9.7 1.5 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) Podoplanin PF05808.11 EST47671.1 - 0.0044 17.1 0.0 0.0075 16.4 0.0 1.3 1 0 0 1 1 1 1 Podoplanin VSP PF03302.13 EST47671.1 - 0.017 14.0 44.4 0.024 13.5 0.1 2.7 2 1 0 2 2 2 0 Giardia variant-specific surface protein DUF4366 PF14283.6 EST47671.1 - 0.021 14.9 0.2 0.12 12.4 0.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) DUF4366 PF14283.6 EST47672.1 - 0.004 17.2 0.0 0.01 15.9 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4366) Podoplanin PF05808.11 EST47672.1 - 0.0087 16.2 0.1 0.0087 16.2 0.1 2.0 2 1 0 2 2 2 1 Podoplanin Trypan_PARP PF05887.11 EST47672.1 - 0.02 14.9 4.9 0.039 13.9 4.9 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) VSP PF03302.13 EST47672.1 - 0.022 13.6 0.1 0.022 13.6 0.1 3.2 2 1 1 3 3 3 0 Giardia variant-specific surface protein DEC-1_N PF04625.13 EST47672.1 - 0.39 9.7 4.5 0.47 9.4 4.5 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region PNP_UDP_1 PF01048.20 EST47674.1 - 1.4e-30 106.3 0.0 1.6e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily YbjM PF11045.8 EST47674.1 - 0.079 13.1 0.0 0.44 10.7 0.0 2.0 2 0 0 2 2 2 0 Putative inner membrane protein of Enterobacteriaceae Nuc_N PF14448.6 EST47675.1 - 0.013 15.3 0.1 0.029 14.2 0.1 1.5 1 0 0 1 1 1 0 Nuclease N terminal zf-rbx1 PF12678.7 EST47676.1 - 1.7e-09 37.8 0.4 1.7e-09 37.8 0.4 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EST47676.1 - 1.7e-09 37.8 2.0 6.7e-08 32.7 0.2 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EST47676.1 - 4.4e-07 29.7 1.1 5.1e-06 26.3 1.1 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EST47676.1 - 4.9e-07 29.5 2.3 2.6e-06 27.2 0.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EST47676.1 - 1.2e-06 28.3 0.2 1.2e-06 28.3 0.2 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EST47676.1 - 2.3e-05 24.3 2.4 0.00013 21.9 2.4 2.2 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 EST47676.1 - 2.9e-05 23.7 3.6 0.00062 19.5 0.2 2.7 2 0 0 2 2 2 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 EST47676.1 - 0.00038 20.0 0.7 0.00038 20.0 0.7 2.0 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 EST47676.1 - 0.00065 19.5 0.1 0.00065 19.5 0.1 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EST47676.1 - 0.002 17.9 0.0 0.002 17.9 0.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EST47676.1 - 0.01 15.8 1.5 0.015 15.3 0.1 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_16 PF17034.5 EST47676.1 - 0.1 12.8 1.0 0.2 11.8 0.4 1.6 1 1 0 1 1 1 0 Zinc-ribbon like family RINGv PF12906.7 EST47676.1 - 0.2 11.8 2.8 0.24 11.6 0.5 2.1 2 0 0 2 2 2 0 RING-variant domain FANCL_C PF11793.8 EST47676.1 - 0.31 11.2 5.7 2.7 8.2 4.3 3.0 2 1 0 2 2 2 0 FANCL C-terminal domain DUF2644 PF10841.8 EST47676.1 - 0.58 10.4 6.0 0.16 12.2 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2644) Ribosomal_L7Ae PF01248.26 EST47678.1 - 9.1e-20 70.2 0.1 1.1e-19 69.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 EST47678.1 - 0.029 14.2 0.0 0.043 13.7 0.0 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain AMP-binding PF00501.28 EST47679.1 - 3.1e-18 65.6 0.0 3.9e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EST47679.1 - 0.0023 18.9 0.2 0.0085 17.1 0.0 2.1 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain RtcB PF01139.17 EST47680.1 - 4.7e-19 68.9 0.1 2.1e-16 60.1 0.0 2.7 2 2 0 2 2 2 2 tRNA-splicing ligase RtcB HPS3_N PF14761.6 EST47682.1 - 0.0054 16.3 0.2 0.012 15.2 0.2 1.5 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 3 DUF1003 PF06210.11 EST47683.1 - 6.4 6.9 10.7 0.37 10.9 4.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) Ras PF00071.22 EST47684.1 - 4.9e-33 114.0 0.0 6.1e-33 113.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EST47684.1 - 1.8e-22 79.8 0.0 2.7e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EST47684.1 - 2.8e-08 33.4 0.0 3e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EST47684.1 - 2.4e-06 27.1 0.0 3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EST47684.1 - 0.073 12.6 0.0 0.22 11.0 0.0 1.7 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain DUF5480 PF17576.2 EST47685.1 - 0.0064 16.4 0.0 0.023 14.6 0.0 1.9 1 0 0 1 1 1 1 Family of unknown function (DUF5480) YlqD PF11068.8 EST47685.1 - 0.087 13.2 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 YlqD protein Proteasome PF00227.26 EST47686.1 - 3.3e-26 92.0 0.0 5e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EST47686.1 - 1.5e-07 31.0 0.1 4.3e-07 29.5 0.1 1.9 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature P_proprotein PF01483.20 EST47686.1 - 0.059 13.4 0.1 0.2 11.7 0.1 1.9 1 1 0 1 1 1 0 Proprotein convertase P-domain HPS3_N PF14761.6 EST47687.1 - 0.0054 16.3 0.2 0.012 15.1 0.2 1.5 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 3 DUF832 PF05734.11 EST47688.1 - 0.098 12.1 0.2 0.13 11.7 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus protein of unknown function (DUF832) RtcB PF01139.17 EST47690.1 - 4.7e-19 68.9 0.1 2.1e-16 60.1 0.0 2.7 2 2 0 2 2 2 2 tRNA-splicing ligase RtcB AMP-binding PF00501.28 EST47691.1 - 3.1e-18 65.6 0.0 3.9e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EST47691.1 - 0.0023 18.9 0.2 0.0085 17.1 0.0 2.1 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain Fmp27_WPPW PF10359.9 EST47692.1 - 0.006 15.5 1.1 0.0082 15.0 1.1 1.1 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Spc7 PF08317.11 EST47692.1 - 0.0066 15.4 4.6 0.01 14.7 4.6 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein RasGAP_C PF03836.15 EST47692.1 - 0.095 12.9 2.9 1.3 9.2 2.0 3.0 2 1 1 3 3 3 0 RasGAP C-terminus NPV_P10 PF05531.12 EST47692.1 - 0.16 12.4 2.3 0.34 11.4 2.3 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Mycoplasma_p37 PF06646.11 EST47692.1 - 0.2 10.8 0.9 0.31 10.2 0.9 1.1 1 0 0 1 1 1 0 High affinity transport system protein p37 Fib_alpha PF08702.10 EST47692.1 - 0.29 11.3 5.1 0.61 10.3 5.1 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family GIT_CC PF16559.5 EST47692.1 - 0.6 10.0 5.2 1.4 8.9 5.2 1.6 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor UPF0242 PF06785.11 EST47692.1 - 0.74 9.9 7.0 0.31 11.1 4.6 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 EST47692.1 - 0.86 10.3 3.7 1.7 9.4 3.7 1.4 1 0 0 1 1 1 0 Initiation control protein YabA SlyX PF04102.12 EST47692.1 - 6 7.6 10.0 14 6.4 10.0 1.6 1 0 0 1 1 1 0 SlyX AAA PF00004.29 EST47694.1 - 1.2e-15 58.1 0.0 1.3e-15 57.9 0.0 1.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SBBP PF06739.11 EST47694.1 - 0.0052 16.7 0.1 0.013 15.5 0.1 1.6 1 0 0 1 1 1 1 Beta-propeller repeat AAA PF00004.29 EST47695.1 - 2.4e-09 37.7 0.0 4.1e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EST47695.1 - 0.0021 18.2 0.0 0.0042 17.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EST47695.1 - 0.029 14.4 0.0 0.062 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EST47695.1 - 0.056 13.9 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EST47695.1 - 0.074 13.4 0.2 0.23 11.8 0.2 1.8 1 1 1 2 2 2 0 AAA ATPase domain Rad17 PF03215.15 EST47695.1 - 0.13 12.2 0.2 0.6 10.0 0.1 2.0 1 1 1 2 2 2 0 Rad17 P-loop domain Aa_trans PF01490.18 EST47696.1 - 2e-50 171.7 53.4 2.4e-50 171.5 53.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DnaJ PF00226.31 EST47697.1 - 3.2e-19 68.8 2.5 3.2e-19 68.8 2.5 2.6 3 0 0 3 3 3 1 DnaJ domain Baculo_PEP_C PF04513.12 EST47697.1 - 0.00068 19.7 0.3 0.0035 17.4 0.1 2.3 2 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_16 PF13432.6 EST47697.1 - 0.0054 17.3 0.0 0.012 16.2 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Aa_trans PF01490.18 EST47698.1 - 1.7e-08 33.6 9.2 1.8e-08 33.5 9.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AAA PF00004.29 EST47699.1 - 2.4e-09 37.7 0.0 4.1e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EST47699.1 - 0.0021 18.2 0.0 0.0042 17.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EST47699.1 - 0.029 14.4 0.0 0.062 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EST47699.1 - 0.056 13.9 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EST47699.1 - 0.074 13.4 0.2 0.23 11.8 0.2 1.8 1 1 1 2 2 2 0 AAA ATPase domain Rad17 PF03215.15 EST47699.1 - 0.13 12.2 0.2 0.6 10.0 0.1 2.0 1 1 1 2 2 2 0 Rad17 P-loop domain AAA PF00004.29 EST47700.1 - 1.6e-35 122.4 0.0 2.7e-35 121.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EST47700.1 - 5.8e-05 23.4 0.0 0.00029 21.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EST47700.1 - 0.00076 18.9 0.0 0.0016 17.9 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EST47700.1 - 0.0011 19.0 0.1 0.0032 17.5 0.1 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EST47700.1 - 0.0024 17.6 0.0 0.006 16.3 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EST47700.1 - 0.0044 16.3 0.0 0.0068 15.7 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 EST47700.1 - 0.0082 16.7 0.0 0.016 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EST47700.1 - 0.0092 16.4 0.0 0.02 15.3 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 EST47700.1 - 0.01 16.2 0.0 0.032 14.6 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA_2 PF07724.14 EST47700.1 - 0.011 15.9 0.0 0.024 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 EST47700.1 - 0.015 15.0 0.0 0.04 13.7 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein SBBP PF06739.11 EST47700.1 - 0.017 15.1 0.0 0.053 13.5 0.0 1.9 1 0 0 1 1 1 0 Beta-propeller repeat AAA_7 PF12775.7 EST47700.1 - 0.036 13.6 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EST47700.1 - 0.055 13.2 0.1 0.13 12.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 EST47700.1 - 0.059 12.7 0.0 0.11 11.8 0.0 1.5 1 1 0 1 1 1 0 KaiC AAA_3 PF07726.11 EST47700.1 - 0.064 13.1 0.0 0.19 11.6 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 EST47700.1 - 0.069 13.7 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 EST47700.1 - 0.078 13.1 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EST47700.1 - 0.097 12.7 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EST47700.1 - 0.1 12.5 0.3 1 9.2 0.1 2.2 2 0 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.26 EST47700.1 - 0.12 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain TniB PF05621.11 EST47700.1 - 0.13 11.6 0.2 2.3 7.6 0.0 2.5 2 1 0 3 3 3 0 Bacterial TniB protein Spc7 PF08317.11 EST47701.1 - 0.066 12.1 11.9 0.011 14.7 4.6 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Vir_act_alpha_C PF10400.9 EST47701.1 - 0.42 11.3 4.2 0.46 11.2 0.1 2.5 2 0 0 2 2 2 0 Virulence activator alpha C-term Laminin_II PF06009.12 EST47701.1 - 0.65 10.0 7.5 3.5 7.7 1.4 2.3 2 0 0 2 2 2 0 Laminin Domain II YabA PF06156.13 EST47701.1 - 3.3 8.4 8.0 1.7 9.3 3.7 2.3 2 0 0 2 2 2 0 Initiation control protein YabA Fmp27_WPPW PF10359.9 EST47701.1 - 3.4 6.4 15.0 0.34 9.7 6.1 2.1 1 1 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain NPV_P10 PF05531.12 EST47701.1 - 3.8 8.0 10.3 0.35 11.4 2.3 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 EST47701.1 - 4.4 7.5 13.9 0.63 10.2 5.1 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family GIT_CC PF16559.5 EST47701.1 - 7.8 6.5 11.6 1.4 8.8 5.2 2.5 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor CENP-H PF05837.12 EST47701.1 - 8.8 6.8 9.0 8.7 6.8 2.3 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) PQ-loop PF04193.14 EST47703.1 - 2.3e-21 75.3 20.7 3.6e-12 45.9 5.0 2.9 3 0 0 3 3 3 2 PQ loop repeat Mad3_BUB1_II PF08171.11 EST47706.1 - 0.056 13.6 0.8 0.22 11.7 0.8 1.9 1 1 0 1 1 1 0 Mad3/BUB1 homology region 2 Laminin_I PF06008.14 EST47707.1 - 0.0072 16.1 12.5 0.092 12.4 0.9 2.1 1 1 1 2 2 2 2 Laminin Domain I Phage_GP20 PF06810.11 EST47707.1 - 0.041 13.7 0.2 0.041 13.7 0.2 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 SlyX PF04102.12 EST47707.1 - 0.064 13.9 0.0 0.064 13.9 0.0 3.1 3 1 1 4 4 4 0 SlyX AATF-Che1 PF13339.6 EST47707.1 - 6.3 7.5 8.8 89 3.8 8.8 2.1 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF745 PF05335.13 EST47707.1 - 7.7 6.2 9.6 3.4 7.3 3.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) NUC153 PF08159.12 EST47708.1 - 5.2 7.0 7.8 4.9 7.1 0.4 2.8 3 0 0 3 3 3 0 NUC153 domain Methyltransf_4 PF02390.17 EST47709.1 - 3.4e-30 104.8 0.0 4.2e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 EST47709.1 - 1.2e-05 25.9 0.0 2.6e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EST47709.1 - 1.6e-05 24.7 0.6 2.3e-05 24.2 0.6 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EST47709.1 - 4.6e-05 23.0 0.0 8.4e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain DOT1 PF08123.13 EST47709.1 - 8.4e-05 22.2 0.0 0.00016 21.3 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 CMAS PF02353.20 EST47709.1 - 0.00088 18.6 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EST47709.1 - 0.00097 19.0 0.0 0.0034 17.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EST47709.1 - 0.0025 18.4 0.0 0.0054 17.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EST47709.1 - 0.0026 18.5 0.0 0.0089 16.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 EST47709.1 - 0.089 12.7 0.1 0.3 11.0 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain Ank_2 PF12796.7 EST47710.1 - 3e-28 98.2 0.3 1.6e-10 41.4 0.2 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EST47710.1 - 1.4e-18 66.7 0.1 0.00016 21.9 0.0 4.8 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 EST47710.1 - 2.6e-18 66.1 1.2 9.5e-06 26.1 0.1 3.9 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EST47710.1 - 1.7e-16 58.6 2.7 0.02 15.4 0.0 5.7 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 EST47710.1 - 4.4e-15 55.3 0.3 0.46 11.0 0.0 5.4 4 1 1 5 5 5 5 Ankyrin repeat Flavi_glycoprot PF00869.20 EST47713.1 - 0.043 13.0 0.0 0.049 12.9 0.0 1.0 1 0 0 1 1 1 0 Flavivirus glycoprotein, central and dimerisation domains HALZ PF02183.18 EST47715.1 - 0.22 11.8 0.2 0.22 11.8 0.2 4.8 4 0 0 4 4 4 0 Homeobox associated leucine zipper MFS_1 PF07690.16 EST47716.1 - 1.8e-11 43.6 54.6 2.6e-11 43.1 46.6 2.9 1 1 0 1 1 1 1 Major Facilitator Superfamily DHC_N2 PF08393.13 EST47718.1 - 1.7e-112 376.5 24.4 1.7e-112 376.5 24.4 3.9 5 1 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 EST47718.1 - 1.3e-107 359.5 0.0 4.1e-107 358.0 0.0 1.9 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 EST47718.1 - 1.2e-99 334.6 25.1 4e-59 200.7 9.4 4.1 4 0 0 4 4 4 2 Dynein heavy chain, N-terminal region 1 AAA_5 PF07728.14 EST47718.1 - 0.0022 18.0 0.1 0.06 13.4 0.0 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EST47718.1 - 0.053 14.1 0.1 1.4 9.5 0.0 3.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EST47718.1 - 0.35 11.1 1.6 13 6.0 0.0 3.9 3 0 0 3 3 3 0 AAA domain FUSC-like PF12805.7 EST47718.1 - 3.2 6.8 8.9 1.9 7.5 0.2 3.6 3 0 0 3 3 3 0 FUSC-like inner membrane protein yccS Pox_A3L PF05288.11 EST47720.1 - 0.032 14.2 0.4 0.17 11.9 0.0 2.5 2 0 0 2 2 2 0 Poxvirus A3L Protein RL10P_insert PF17777.1 EST47720.1 - 0.57 10.2 2.7 1.9 8.6 0.9 2.4 2 0 0 2 2 2 0 Insertion domain in 60S ribosomal protein L10P NABP PF07990.12 EST47720.1 - 0.58 9.6 6.7 1 8.9 6.7 1.3 1 0 0 1 1 1 0 Nucleic acid binding protein NABP MFS_1 PF07690.16 EST47721.1 - 2.4e-27 95.8 39.9 2.4e-27 95.8 39.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1616 PF07760.11 EST47721.1 - 2.2 7.6 8.4 0.21 10.9 3.2 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1616) MORN PF02493.20 EST47722.1 - 0.00037 20.2 7.5 0.015 15.1 0.2 3.6 4 0 0 4 4 4 2 MORN repeat EF-hand_7 PF13499.6 EST47723.1 - 1.7e-07 31.6 3.4 8.7e-06 26.1 3.4 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EST47723.1 - 2.9e-07 30.2 0.7 6.7e-07 29.1 0.7 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EST47723.1 - 5.4e-05 22.4 1.7 0.0021 17.5 0.1 2.9 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 EST47723.1 - 0.00019 21.1 1.9 0.054 13.4 0.0 3.2 2 1 1 3 3 3 1 EF-hand domain DUF5388 PF17363.2 EST47723.1 - 0.024 14.8 0.3 0.037 14.2 0.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5388) Death PF00531.22 EST47723.1 - 0.025 14.7 0.0 0.05 13.8 0.0 1.6 1 1 0 1 1 1 0 Death domain Fe_hyd_lg_C PF02906.14 EST47723.1 - 0.056 13.1 0.2 0.057 13.1 0.2 1.2 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain UPF0231 PF06062.11 EST47723.1 - 0.062 13.6 0.2 0.081 13.2 0.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0231) SWI2_SNF2 PF18766.1 EST47723.1 - 0.069 12.8 0.9 0.097 12.3 0.9 1.2 1 0 0 1 1 1 0 SWI2/SNF2 ATPase Slx4 PF09494.10 EST47723.1 - 0.08 12.9 0.0 0.29 11.1 0.0 2.0 1 1 0 1 1 1 0 Slx4 endonuclease Alpha_L_fucos PF01120.17 EST47724.1 - 0.031 13.8 4.4 0.034 13.6 4.4 1.1 1 0 0 1 1 1 0 Alpha-L-fucosidase Methyltransf_12 PF08242.12 EST47725.1 - 0.42 11.4 2.9 1.7 9.4 0.0 2.6 3 0 0 3 3 3 0 Methyltransferase domain HCNGP PF07818.13 EST47725.1 - 7.9 7.2 12.1 0.23 12.1 0.5 3.3 2 2 0 3 3 3 0 HCNGP-like protein Not3 PF04065.15 EST47727.1 - 3.6e-23 82.2 13.8 3.6e-23 82.2 13.8 2.8 2 1 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 EST47727.1 - 4.1e-05 23.7 0.0 0.00018 21.6 0.0 2.2 1 1 0 1 1 1 1 NOT2 / NOT3 / NOT5 family CMS1 PF14617.6 EST47727.1 - 0.031 13.6 0.2 0.059 12.7 0.2 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit HD_3 PF13023.6 EST47727.1 - 0.4 10.6 2.5 0.48 10.3 0.4 2.3 2 0 0 2 2 2 0 HD domain DUF4164 PF13747.6 EST47727.1 - 0.48 10.7 13.4 0.26 11.6 1.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) MapZ_EC1 PF18041.1 EST47727.1 - 1.5 9.1 10.6 0.52 10.5 0.4 3.2 3 0 0 3 3 3 0 MapZ extracellular domain 1 Gaa1 PF04114.14 EST47728.1 - 0.15 11.1 5.1 0.15 11.0 5.1 1.1 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component MutS_V PF00488.21 EST47729.1 - 2.2e-38 132.2 1.2 3.9e-38 131.4 1.2 1.4 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.20 EST47729.1 - 2.4e-17 63.2 0.0 6.1e-17 61.9 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.18 EST47729.1 - 1.8e-13 51.1 1.2 3.3e-13 50.3 1.2 1.4 1 0 0 1 1 1 1 MutS domain III AAA_14 PF13173.6 EST47729.1 - 0.0026 17.8 0.1 0.04 14.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain MutS_II PF05188.17 EST47729.1 - 0.0027 18.0 2.0 0.02 15.2 0.0 2.9 3 0 0 3 3 3 1 MutS domain II AAA_29 PF13555.6 EST47729.1 - 0.07 12.9 0.1 0.2 11.4 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain CABS1 PF15367.6 EST47729.1 - 0.14 11.2 0.1 0.23 10.5 0.1 1.2 1 0 0 1 1 1 0 Calcium-binding and spermatid-specific protein 1 ABC_tran PF00005.27 EST47729.1 - 0.4 11.2 3.4 1 9.9 0.2 2.7 2 0 0 2 2 2 0 ABC transporter DUF502 PF04367.13 EST47730.1 - 0.072 13.0 0.2 2.1 8.3 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF502) HrpA_pilin PF09589.10 EST47730.1 - 0.28 11.9 3.6 2 9.2 3.6 2.6 1 0 0 1 1 1 0 HrpA pilus formation protein DUF4234 PF14018.6 EST47731.1 - 0.034 14.3 0.6 0.12 12.6 0.6 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) MFS_3 PF05977.13 EST47731.1 - 0.16 10.4 0.0 0.24 9.8 0.0 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector DUF4064 PF13273.6 EST47731.1 - 0.5 10.7 4.3 0.29 11.4 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Laminin_EGF PF00053.24 EST47732.1 - 0.019 15.1 9.3 0.019 15.1 9.3 2.9 2 1 1 3 3 3 0 Laminin EGF domain LRR_8 PF13855.6 EST47733.1 - 6.5e-06 25.8 0.5 0.00014 21.5 0.0 2.8 2 2 0 2 2 2 1 Leucine rich repeat LRRNT_2 PF08263.12 EST47733.1 - 0.0045 17.3 0.1 0.0084 16.4 0.1 1.5 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_4 PF12799.7 EST47733.1 - 0.026 15.0 1.2 2.6 8.6 0.1 3.1 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) Aa_trans PF01490.18 EST47734.1 - 3.7e-37 128.0 48.2 5.8e-37 127.4 48.2 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EST47734.1 - 7.7e-05 21.9 43.3 0.00047 19.3 43.3 2.0 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family AA_permease_2 PF13520.6 EST47734.1 - 0.26 10.1 53.5 0.0053 15.6 32.2 2.7 1 1 1 2 2 2 0 Amino acid permease RHSP PF07999.11 EST47735.1 - 0.023 13.5 0.0 0.84 8.4 0.0 2.0 1 1 1 2 2 2 0 Retrotransposon hot spot protein CitMHS PF03600.16 EST47735.1 - 0.13 11.5 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Citrate transporter LapA_dom PF06305.11 EST47736.1 - 2.3 8.1 5.9 25 4.8 2.0 2.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain ATP-synt_F PF01990.17 EST47737.1 - 2.2e-17 63.1 0.0 2.7e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit FMN_red PF03358.15 EST47738.1 - 0.00058 19.6 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Lactamase_B PF00753.27 EST47738.1 - 0.0048 16.9 0.0 0.012 15.7 0.0 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily PGM_PMM_I PF02878.16 EST47738.1 - 0.03 14.0 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I Flavodoxin_5 PF12724.7 EST47738.1 - 0.057 13.7 0.0 0.097 12.9 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain BAR PF03114.18 EST47738.1 - 0.12 12.0 0.6 4.6 6.8 0.0 2.4 2 0 0 2 2 2 0 BAR domain DUF5344 PF17279.2 EST47738.1 - 6.9 7.3 6.5 0.87 10.2 0.7 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5344) Annexin PF00191.20 EST47740.1 - 3.3e-07 30.3 5.3 0.00013 22.0 0.3 4.6 3 2 0 3 3 3 2 Annexin Sec6 PF06046.13 EST47740.1 - 0.019 13.4 0.0 0.046 12.1 0.0 1.6 1 1 0 1 1 1 0 Exocyst complex component Sec6 MFS_1 PF07690.16 EST47741.1 - 1.4e-07 30.8 17.3 1.4e-07 30.8 17.3 3.2 1 1 2 3 3 3 2 Major Facilitator Superfamily PX PF00787.24 EST47742.1 - 0.031 14.3 4.9 0.34 10.9 4.9 2.0 1 1 0 1 1 1 0 PX domain E2F_TDP PF02319.20 EST47743.1 - 6.6e-06 26.1 0.1 2.7e-05 24.1 0.1 2.0 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain GTA_TIM PF13547.6 EST47744.1 - 0.02 14.2 0.0 0.023 14.0 0.0 1.1 1 0 0 1 1 1 0 GTA TIM-barrel-like domain DUF1257 PF06868.11 EST47744.1 - 0.061 13.6 0.7 0.14 12.4 0.2 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1257) Opi1 PF08618.10 EST47744.1 - 0.086 12.1 0.4 0.094 12.0 0.4 1.2 1 1 0 1 1 1 0 Transcription factor Opi1 LCAT PF02450.15 EST47745.1 - 7.7e-11 41.8 1.8 2.4e-10 40.2 1.8 1.9 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase PGAP1 PF07819.13 EST47745.1 - 0.015 15.0 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein DUF900 PF05990.12 EST47745.1 - 0.021 14.4 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.8 EST47745.1 - 0.035 13.4 0.0 0.11 11.7 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EST47745.1 - 0.063 13.9 0.0 0.1 13.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family ER_lumen_recept PF00810.18 EST47747.1 - 3.1e-45 154.6 16.6 4.5e-45 154.1 16.6 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor Cortex-I_coil PF09304.10 EST47748.1 - 0.00016 21.8 4.4 0.00016 21.8 4.4 8.4 7 2 2 9 9 9 2 Cortexillin I, coiled coil DUF4898 PF16239.5 EST47748.1 - 0.026 14.5 0.1 0.12 12.4 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4898) RuvC PF02075.17 EST47748.1 - 0.087 12.7 4.8 2.2 8.1 0.2 3.1 2 0 0 2 2 2 0 Crossover junction endodeoxyribonuclease RuvC YvrJ PF12841.7 EST47748.1 - 3 7.5 4.2 17 5.1 0.2 3.8 4 0 0 4 4 4 0 YvrJ protein family Mrr_N PF14338.6 EST47748.1 - 4.5 7.5 10.0 8.4 6.6 0.2 4.3 3 1 0 3 3 3 0 Mrr N-terminal domain DUF1664 PF07889.12 EST47750.1 - 0.18 11.9 14.6 0.88 9.6 2.4 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) CHAD PF05235.14 EST47750.1 - 0.92 9.4 8.6 1.5 8.7 8.6 1.4 1 1 0 1 1 1 0 CHAD domain DHquinase_II PF01220.19 EST47750.1 - 7.1 6.3 9.9 1.3 8.7 1.1 2.6 2 1 0 2 2 2 0 Dehydroquinase class II CagY_I PF14585.6 EST47754.1 - 0.034 14.2 0.0 0.06 13.4 0.0 1.5 1 0 0 1 1 1 0 CagY type 1 repeat Annexin PF00191.20 EST47757.1 - 5e-24 84.2 13.7 3.2e-10 39.9 0.3 5.1 5 0 0 5 5 5 5 Annexin Surp PF01805.20 EST47757.1 - 0.016 15.2 0.5 0.044 13.8 0.1 1.9 2 0 0 2 2 2 0 Surp module CCAP PF11105.8 EST47758.1 - 0.061 13.3 3.8 0.31 11.0 1.0 2.3 1 1 1 2 2 2 0 Arthropod cardioacceleratory peptide 2a Laminin_EGF PF00053.24 EST47760.1 - 0.00015 21.8 10.5 0.00015 21.8 10.5 10.4 4 3 5 9 9 9 3 Laminin EGF domain EGF_2 PF07974.13 EST47760.1 - 0.00028 21.2 167.9 0.0059 16.9 12.8 12.6 11 3 1 12 12 12 7 EGF-like domain S1FA PF04689.13 EST47760.1 - 0.18 12.0 0.1 0.33 11.1 0.1 1.4 1 0 0 1 1 1 0 DNA binding protein S1FA DUF515 PF04415.12 EST47760.1 - 0.29 9.5 0.1 0.41 9.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF1129 PF06570.11 EST47760.1 - 0.32 10.5 0.4 0.45 10.0 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) CAP PF00188.26 EST47761.1 - 0.00048 21.0 0.0 0.00079 20.3 0.0 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Podoplanin PF05808.11 EST47761.1 - 0.065 13.3 0.3 0.11 12.6 0.3 1.2 1 0 0 1 1 1 0 Podoplanin His_Phos_2 PF00328.22 EST47762.1 - 1e-12 48.1 0.3 2.1e-10 40.5 0.3 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Saf_2TM PF18303.1 EST47762.1 - 0.02 14.5 0.5 0.039 13.5 0.5 1.5 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain Orf78 PF06024.12 EST47762.1 - 0.026 14.8 1.9 0.036 14.4 0.7 1.9 2 0 0 2 2 2 0 Orf78 (ac78) TFX_C PF14601.6 EST47762.1 - 0.11 12.5 0.4 0.26 11.3 0.4 1.7 1 0 0 1 1 1 0 DNA_binding protein, TFX, C-term DUF3139 PF11337.8 EST47762.1 - 2.2 9.0 7.5 1.3 9.7 4.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Pkinase PF00069.25 EST47763.1 - 9.2e-48 162.9 0.2 1.2e-47 162.5 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST47763.1 - 2.3e-27 95.9 0.1 3e-27 95.6 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EST47763.1 - 4.8e-05 22.3 0.0 8e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Metallophos PF00149.28 EST47764.1 - 2.3e-20 74.0 0.4 3.8e-20 73.3 0.1 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase E2F_TDP PF02319.20 EST47765.1 - 5.1e-16 58.5 2.8 1.3e-07 31.5 0.5 2.2 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 EST47765.1 - 1.9e-05 24.4 1.8 0.0013 18.6 0.3 3.1 2 2 1 3 3 3 1 Sugar-specific transcriptional regulator TrmB HTH_23 PF13384.6 EST47765.1 - 0.00085 19.1 0.1 0.002 17.9 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_11 PF08279.12 EST47765.1 - 0.00096 19.0 0.2 0.00096 19.0 0.2 2.1 2 1 0 2 2 2 1 HTH domain B-block_TFIIIC PF04182.12 EST47765.1 - 0.0033 17.6 3.3 0.11 12.7 0.2 2.3 1 1 0 2 2 2 1 B-block binding subunit of TFIIIC EAP30 PF04157.16 EST47765.1 - 0.0075 15.6 0.1 0.012 14.9 0.1 1.3 1 0 0 1 1 1 1 EAP30/Vps36 family HrcA_DNA-bdg PF03444.15 EST47765.1 - 0.009 15.6 2.4 0.097 12.3 0.4 2.8 3 0 0 3 3 3 1 Winged helix-turn-helix transcription repressor, HrcA DNA-binding PAP_fibrillin PF04755.12 EST47765.1 - 0.078 12.9 1.3 0.31 11.0 0.1 2.0 1 1 0 2 2 2 0 PAP_fibrillin HTH_20 PF12840.7 EST47765.1 - 0.088 12.9 0.0 0.31 11.2 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain ThiD2 PF17792.1 EST47765.1 - 0.11 13.0 0.2 0.28 11.6 0.0 1.7 1 1 1 2 2 2 0 ThiD2 family PDGF_N PF04692.13 EST47766.1 - 0.053 14.3 2.5 0.064 14.0 0.6 1.9 2 0 0 2 2 2 0 Platelet-derived growth factor, N terminal region gp45-slide_C PF09116.10 EST47768.1 - 0.091 12.8 0.4 15 5.7 0.1 2.2 2 0 0 2 2 2 0 gp45 sliding clamp, C terminal KKLCAg1 PF15204.6 EST47769.1 - 0.014 15.5 0.4 0.042 14.0 0.4 1.9 1 0 0 1 1 1 0 Kita-kyushu lung cancer antigen 1 bZIP_1 PF00170.21 EST47770.1 - 0.15 12.2 0.6 0.15 12.2 0.6 1.8 2 0 0 2 2 2 0 bZIP transcription factor TLD PF07534.16 EST47771.1 - 7.2e-09 36.0 0.5 7.2e-09 36.0 0.5 3.2 2 2 0 2 2 2 1 TLD Syntaxin PF00804.25 EST47772.1 - 1.3e-07 31.5 16.4 1.3e-07 31.5 16.4 1.5 1 1 0 1 1 1 1 Syntaxin SNARE PF05739.19 EST47772.1 - 0.00021 21.2 1.5 0.0011 18.9 1.5 2.4 1 1 0 1 1 1 1 SNARE domain cwf21 PF08312.12 EST47772.1 - 0.012 15.7 1.2 11 6.2 0.0 3.0 2 1 0 2 2 2 0 cwf21 domain MMR_HSR1_C PF08438.10 EST47772.1 - 0.09 13.4 0.2 0.09 13.4 0.2 2.7 2 1 0 2 2 2 0 GTPase of unknown function C-terminal DUF5365 PF17326.2 EST47772.1 - 1.6 9.1 11.7 0.81 10.1 7.6 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5365) DUF4699 PF15770.5 EST47773.1 - 0.24 11.1 1.1 0.6 9.8 1.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4699) DUF4898 PF16239.5 EST47776.1 - 0.023 14.7 1.2 0.042 13.8 0.1 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4898) Striatin PF08232.12 EST47776.1 - 0.081 13.5 0.6 0.081 13.5 0.6 2.0 2 0 0 2 2 2 0 Striatin family Serine_rich PF08824.10 EST47776.1 - 0.58 10.2 7.4 0.1 12.6 0.9 2.0 1 1 1 2 2 2 0 Serine rich protein interaction domain DUF2195 PF09961.9 EST47776.1 - 1.3 9.0 4.7 1.5 8.8 0.9 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2195) GTP_EFTU PF00009.27 EST47777.1 - 1.7e-30 106.0 0.1 2.6e-30 105.4 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EST47777.1 - 1.2e-07 31.8 0.0 4.7e-07 29.9 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 EST47777.1 - 5.7e-06 26.6 1.8 1.4e-05 25.3 0.3 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 SRPRB PF09439.10 EST47777.1 - 6e-06 25.8 0.1 2.4e-05 23.8 0.0 1.8 1 1 0 2 2 2 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EST47777.1 - 0.0028 17.4 0.6 0.036 13.8 0.6 2.5 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 EST47777.1 - 0.0091 15.5 0.1 0.046 13.3 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EST47777.1 - 0.016 15.1 1.7 0.047 13.6 0.2 2.3 2 1 1 3 3 3 0 RsgA GTPase ATP_bind_1 PF03029.17 EST47777.1 - 0.022 14.6 0.1 0.31 10.8 0.0 2.5 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein ACT PF01842.25 EST47778.1 - 0.43 10.4 2.1 8 6.3 0.1 3.0 3 0 0 3 3 3 0 ACT domain Oxidored_FMN PF00724.20 EST47779.1 - 4.6e-08 32.7 0.2 3e-06 26.8 0.5 2.7 2 1 0 2 2 2 1 NADH:flavin oxidoreductase / NADH oxidase family Phospholip_B PF04916.13 EST47780.1 - 6.1e-83 279.2 21.5 7.6e-83 278.9 21.5 1.0 1 0 0 1 1 1 1 Phospholipase B DUF5085 PF16895.5 EST47780.1 - 0.17 12.2 5.1 0.4 11.0 0.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5085) Laminin_EGF PF00053.24 EST47780.1 - 2.4 8.4 12.4 10 6.3 12.4 2.1 1 1 0 1 1 1 0 Laminin EGF domain Cyclin_N PF00134.23 EST47781.1 - 3.2e-09 36.6 1.1 9.3e-09 35.1 0.4 2.0 2 1 0 2 2 2 1 Cyclin, N-terminal domain AsmA_2 PF13502.6 EST47783.1 - 0.0051 16.4 3.8 0.011 15.2 3.8 1.5 1 0 0 1 1 1 1 AsmA-like C-terminal region GrpB PF04229.14 EST47783.1 - 0.16 12.2 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 GrpB protein DUF4392 PF14336.6 EST47785.1 - 2.9e-33 115.6 0.0 8.8e-33 114.0 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4392) Methyltransf_15 PF09445.10 EST47785.1 - 1.1e-11 44.6 0.4 2.2e-11 43.6 0.4 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase TFIIF_beta_N PF17683.1 EST47785.1 - 0.14 12.9 0.1 0.26 12.0 0.1 1.5 1 0 0 1 1 1 0 TFIIF, beta subunit N-terminus Pentapeptide PF00805.22 EST47786.1 - 0.63 9.7 4.2 17 5.2 0.1 3.5 4 0 0 4 4 4 0 Pentapeptide repeats (8 copies) DUF2048 PF09752.9 EST47787.1 - 0.011 14.8 0.3 0.026 13.6 0.3 1.6 1 0 0 1 1 1 0 Abhydrolase domain containing 18 NOT2_3_5 PF04153.18 EST47788.1 - 0.0015 18.6 1.8 0.0016 18.5 1.8 1.2 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Serine_protease PF18405.1 EST47788.1 - 0.058 12.6 0.7 0.079 12.1 0.7 1.2 1 0 0 1 1 1 0 Gammaproteobacterial serine protease MORN PF02493.20 EST47790.1 - 1e-14 53.4 23.5 0.0023 17.7 0.1 6.5 6 0 0 6 6 6 5 MORN repeat tRNA_U5-meth_tr PF05958.11 EST47791.1 - 2.4e-14 53.1 0.0 9.5e-10 38.0 0.0 2.5 1 1 1 2 2 2 2 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 EST47791.1 - 3e-08 33.6 0.4 9.4e-08 32.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EST47791.1 - 5.1e-08 32.7 0.0 1.1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EST47791.1 - 1.3e-05 25.9 0.0 3.1e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EST47791.1 - 0.00049 20.8 0.2 0.0021 18.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EST47791.1 - 0.0012 19.5 0.1 0.0028 18.3 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EST47791.1 - 0.0013 18.8 0.1 0.0013 18.8 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain AviRa PF11599.8 EST47791.1 - 0.0058 16.1 0.1 0.011 15.2 0.1 1.4 1 0 0 1 1 1 1 RRNA methyltransferase AviRa Cons_hypoth95 PF03602.15 EST47791.1 - 0.03 14.0 0.0 0.12 12.0 0.0 2.0 1 1 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_23 PF13489.6 EST47791.1 - 0.058 13.2 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EST47791.1 - 0.092 12.1 0.1 0.19 11.1 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Aminotran_1_2 PF00155.21 EST47794.1 - 6.9e-05 22.2 0.0 0.099 11.8 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class I and II ThiS PF02597.20 EST47798.1 - 4.2e-05 24.1 0.0 0.00018 22.1 0.0 1.8 2 0 0 2 2 2 1 ThiS family DUF501 PF04417.12 EST47799.1 - 1.3 8.8 4.5 2.9 7.7 0.3 3.9 2 0 0 2 2 2 0 Protein of unknown function (DUF501) TMEM52 PF14979.6 EST47802.1 - 0.12 12.3 1.1 0.18 11.7 1.1 1.4 1 1 0 1 1 1 0 Transmembrane 52 HCV_NS4a PF01006.20 EST47802.1 - 2.1 8.2 6.5 2 8.3 3.1 2.3 1 1 1 2 2 2 0 Hepatitis C virus non-structural protein NS4a PHTB1_N PF14727.6 EST47804.1 - 4.7e-35 121.8 15.4 1.1e-32 114.0 7.7 3.0 3 0 0 3 3 3 2 PTHB1 N-terminus HU-CCDC81_euk_2 PF18289.1 EST47806.1 - 3.8e-13 49.4 0.2 4.4e-12 46.0 0.0 2.2 2 0 0 2 2 2 1 CCDC81 eukaryotic HU domain 2 HU-CCDC81_euk_1 PF14908.6 EST47806.1 - 0.00013 22.1 0.1 0.00033 20.7 0.0 1.7 2 0 0 2 2 2 1 CCDC81 eukaryotic HU domain 1 tRNA-synt_1e PF01406.19 EST47807.1 - 5e-100 334.7 0.2 1.1e-99 333.6 0.2 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EST47807.1 - 3.5e-07 29.3 0.4 0.0059 15.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EST47807.1 - 0.037 12.3 0.1 0.13 10.4 0.0 1.9 3 0 0 3 3 3 0 tRNA synthetases class I (I, L, M and V) VSP PF03302.13 EST47812.1 - 0.13 11.0 79.5 2.9 6.7 36.4 3.9 1 1 2 3 3 3 0 Giardia variant-specific surface protein Rax2 PF12768.7 EST47812.1 - 0.25 10.8 0.0 0.33 10.4 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity CbtA_toxin PF06755.12 EST47813.1 - 0.091 12.8 0.1 0.22 11.5 0.1 1.6 1 0 0 1 1 1 0 CbtA_toxin of type IV toxin-antitoxin system Urb2 PF10441.9 EST47813.1 - 5.8 6.8 14.3 0.25 11.2 0.1 3.4 3 1 0 3 3 3 0 Urb2/Npa2 family SHIPPO-rpt PF07004.12 EST47814.1 - 0.0011 19.7 21.7 1 10.4 0.0 7.6 9 0 0 9 9 9 3 Sperm-tail PG-rich repeat ECR1_N PF14382.6 EST47814.1 - 0.0042 16.9 0.0 1.2 9.0 0.0 3.4 3 0 0 3 3 3 1 Exosome complex exonuclease RRP4 N-terminal region Pkinase PF00069.25 EST47815.1 - 8.3e-45 153.2 5.9 2.4e-41 141.8 2.0 3.3 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EST47815.1 - 1.6e-37 129.2 2.5 1.2e-32 113.3 0.4 3.1 2 1 1 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 EST47815.1 - 0.009 15.4 0.0 0.023 14.0 0.0 1.6 1 0 0 1 1 1 1 Kinase-like BLYB PF05289.11 EST47816.1 - 0.26 11.5 6.1 2 8.7 0.1 3.2 2 1 1 3 3 3 0 Borrelia hemolysin accessory protein Methyltransf_23 PF13489.6 EST47817.1 - 1.4e-15 57.5 0.0 2.1e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EST47817.1 - 2.3e-10 41.0 0.0 7.3e-10 39.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EST47817.1 - 5.2e-10 40.0 0.0 1.5e-09 38.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EST47817.1 - 9.9e-10 39.0 0.1 1.9e-08 34.9 0.1 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EST47817.1 - 8.3e-09 35.4 1.2 6.8e-07 29.2 1.2 2.3 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 EST47817.1 - 0.0042 16.7 0.2 0.012 15.2 0.2 1.7 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.15 EST47817.1 - 0.0046 16.8 0.0 0.0071 16.2 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase NodS PF05401.11 EST47817.1 - 0.064 12.9 0.0 0.17 11.5 0.0 1.7 1 1 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 EST47817.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain GIT_CC PF16559.5 EST47819.1 - 0.012 15.4 3.2 0.071 13.0 0.6 2.2 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor CASP_C PF08172.12 EST47819.1 - 0.047 13.0 0.1 0.049 13.0 0.1 1.3 1 1 0 1 1 1 0 CASP C terminal DUF3496 PF12001.8 EST47819.1 - 0.32 11.4 4.5 2.1 8.7 4.5 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3496) bZIP_1 PF00170.21 EST47819.1 - 1.2 9.3 9.3 1.3 9.2 2.5 2.2 2 0 0 2 2 2 0 bZIP transcription factor Sec7 PF01369.20 EST47820.1 - 4.5e-06 26.5 0.2 1.1e-05 25.2 0.2 1.7 1 0 0 1 1 1 1 Sec7 domain TPR_8 PF13181.6 EST47821.1 - 0.021 15.0 0.0 0.096 13.0 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF445 PF04286.12 EST47822.1 - 0.00023 21.1 13.4 0.00029 20.8 13.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF445) SecD_SecF PF02355.16 EST47822.1 - 0.00065 19.1 15.0 4.3e+02 0.1 15.0 3.7 1 1 0 1 1 1 0 Protein export membrane protein GerPC PF10737.9 EST47822.1 - 0.0007 19.7 15.3 0.0011 19.0 15.3 1.3 1 0 0 1 1 1 1 Spore germination protein GerPC EcsC PF12787.7 EST47822.1 - 0.0065 16.2 7.8 1.4 8.6 7.8 2.5 1 1 0 1 1 1 1 EcsC protein family YpjP PF14005.6 EST47822.1 - 0.081 13.0 14.8 67 3.5 14.8 2.4 1 1 0 1 1 1 0 YpjP-like protein PdaC PF13739.6 EST47822.1 - 0.27 12.2 37.4 1.8e+04 -17.0 37.5 4.7 1 1 0 1 1 0 0 Deacetylase PdaC Spo0A_C PF08769.11 EST47822.1 - 0.38 10.9 15.3 2.9e+02 1.6 15.3 2.6 1 1 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal Glycoprot_B_PH2 PF17417.2 EST47822.1 - 0.54 10.6 15.7 5.5e+03 -2.2 15.7 3.6 1 1 0 1 1 1 0 Herpesvirus Glycoprotein B PH-like domain PIN_8 PF18476.1 EST47822.1 - 1.2 8.9 12.0 2 8.2 12.0 1.3 1 0 0 1 1 1 0 PIN like domain TRAPPC-Trs85 PF12739.7 EST47822.1 - 1.3 7.9 18.9 14 4.5 18.9 2.0 1 1 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TonB_2 PF13103.6 EST47822.1 - 3.2 8.1 11.6 1.2e+03 -0.2 11.6 3.8 1 1 0 1 1 1 0 TonB C terminal CEL_III_C PF18054.1 EST47822.1 - 3.3 7.8 22.5 88 3.1 22.5 2.2 1 1 0 1 1 1 0 CEL-III C-terminal TFIIA PF03153.13 EST47822.1 - 4.9 7.0 26.0 6.3 6.7 26.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FHIPEP PF00771.20 EST47822.1 - 5.8 5.3 13.3 12 4.2 13.3 1.5 1 1 0 1 1 1 0 FHIPEP family HI0933_like PF03486.14 EST47822.1 - 8.7 4.9 15.4 1.8e+02 0.6 15.4 2.0 1 1 0 1 1 1 0 HI0933-like protein Vps39_2 PF10367.9 EST47822.1 - 9 6.8 14.9 1e+04 -3.0 14.9 2.7 1 1 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 TaqI_C PF12950.7 EST47823.1 - 0.052 13.6 2.8 0.062 13.4 2.8 1.2 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain Clathrin-link PF09268.10 EST47823.1 - 0.69 9.3 0.1 0.69 9.3 0.1 2.6 3 0 0 3 3 3 0 Clathrin, heavy-chain linker ASH PF15780.5 EST47825.1 - 0.00011 22.3 0.0 0.059 13.6 0.0 4.7 4 1 1 5 5 5 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1132 PF06575.12 EST47826.1 - 0.0027 18.1 1.6 0.0028 18.0 0.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1132) Deltameth_res PF16020.5 EST47826.1 - 0.02 14.8 1.2 0.076 12.9 1.2 2.0 1 0 0 1 1 1 0 Deltamethrin resistance DUF3099 PF11298.8 EST47826.1 - 0.089 12.9 4.0 0.71 10.0 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) ODV-E18 PF10717.9 EST47826.1 - 0.095 12.6 2.1 3.5 7.6 1.2 2.2 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Pox_EPC_I2-L1 PF12575.8 EST47826.1 - 0.18 12.0 7.4 0.15 12.3 1.1 2.3 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 RDD PF06271.12 EST47826.1 - 0.89 9.8 6.5 0.49 10.6 1.4 2.0 2 0 0 2 2 2 0 RDD family DUF3055 PF11256.8 EST47828.1 - 0.13 12.6 0.1 0.23 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3055) DUF3307 PF11750.8 EST47829.1 - 0.00092 19.3 5.9 0.0016 18.5 5.9 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3307) dNK PF01712.19 EST47831.1 - 2.1e-43 148.6 0.5 2.3e-43 148.4 0.5 1.0 1 0 0 1 1 1 1 Deoxynucleoside kinase Thymidylate_kin PF02223.17 EST47831.1 - 1.7e-08 34.4 0.2 4.2e-08 33.1 0.2 1.7 1 1 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 EST47831.1 - 2.1e-07 31.3 0.0 2.5e-07 31.1 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EST47831.1 - 1.5e-05 25.2 0.0 2.2e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EST47831.1 - 0.00039 21.0 0.0 0.002 18.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EST47831.1 - 0.00068 20.1 0.0 0.046 14.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 EST47831.1 - 0.075 13.0 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 EST47831.1 - 0.17 11.1 0.0 0.59 9.4 0.0 1.8 3 0 0 3 3 3 0 Zeta toxin Dynamin_N PF00350.23 EST47831.1 - 0.19 11.8 0.0 0.27 11.3 0.0 1.3 1 1 0 1 1 1 0 Dynamin family dNK PF01712.19 EST47832.1 - 2.1e-43 148.6 0.5 2.3e-43 148.4 0.5 1.0 1 0 0 1 1 1 1 Deoxynucleoside kinase Thymidylate_kin PF02223.17 EST47832.1 - 1.7e-08 34.4 0.2 4.2e-08 33.1 0.2 1.7 1 1 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 EST47832.1 - 2.1e-07 31.3 0.0 2.5e-07 31.1 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EST47832.1 - 1.5e-05 25.2 0.0 2.2e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EST47832.1 - 0.00039 21.0 0.0 0.002 18.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EST47832.1 - 0.00068 20.1 0.0 0.046 14.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 EST47832.1 - 0.075 13.0 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 EST47832.1 - 0.17 11.1 0.0 0.59 9.4 0.0 1.8 3 0 0 3 3 3 0 Zeta toxin Dynamin_N PF00350.23 EST47832.1 - 0.19 11.8 0.0 0.27 11.3 0.0 1.3 1 1 0 1 1 1 0 Dynamin family pXO2-34 PF17362.2 EST47833.1 - 0.15 11.9 0.2 0.29 11.0 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function DUF3587 PF12132.8 EST47833.1 - 0.16 11.4 0.4 0.31 10.4 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3587) KA1 PF02149.19 EST47834.1 - 0.044 13.6 0.2 13 5.6 0.0 3.2 3 0 0 3 3 3 0 Kinase associated domain 1 Chlorophyllase2 PF12740.7 EST47835.1 - 0.12 11.2 0.1 0.13 11.2 0.1 1.0 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF2335 PF10097.9 EST47837.1 - 0.048 13.6 0.1 0.098 12.6 0.1 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2335) Spec3 PF15795.5 EST47840.1 - 0.72 10.4 12.7 1.6 9.3 11.2 2.1 1 1 1 2 2 2 0 Ectodermal ciliogenesis protein hEGF PF12661.7 EST47841.1 - 0.011 16.4 2.7 0.011 16.4 2.7 6.2 5 2 0 5 5 5 0 Human growth factor-like EGF EGF_2 PF07974.13 EST47841.1 - 0.016 15.6 8.4 0.016 15.6 8.4 5.8 5 1 0 5 5 5 0 EGF-like domain S1FA PF04689.13 EST47841.1 - 0.022 14.9 0.0 0.037 14.2 0.0 1.2 1 0 0 1 1 1 0 DNA binding protein S1FA UL41A PF17591.2 EST47843.1 - 0.0043 17.1 0.1 0.0076 16.3 0.1 1.3 1 0 0 1 1 1 1 Herpesvirus UL41A Protocadherin PF08374.11 EST47843.1 - 0.086 12.8 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Protocadherin DUF5385 PF17359.2 EST47843.1 - 0.23 11.0 1.3 0.3 10.6 1.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Hexapep PF00132.24 EST47844.1 - 2.2e-12 46.2 14.8 4.9e-09 35.6 6.8 3.5 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EST47844.1 - 6.1e-10 38.7 13.6 4.2e-07 29.6 4.7 3.6 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 EST47844.1 - 4.5e-06 26.8 0.0 6.5e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase 4HBT PF03061.22 EST47844.1 - 0.12 12.8 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 Thioesterase superfamily MatE PF01554.18 EST47846.1 - 1.8e-26 92.8 24.6 1.3e-16 60.7 9.2 2.7 3 0 0 3 3 3 2 MatE POR_N PF01855.19 EST47847.1 - 1.5e-65 221.2 0.3 2.4e-65 220.5 0.3 1.3 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 EST47847.1 - 9e-19 68.2 0.0 1.7e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase EKR PF10371.9 EST47847.1 - 1.8e-14 53.3 0.0 5.9e-14 51.6 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function PFOR_II PF17147.4 EST47847.1 - 3.3e-10 40.2 0.1 1.1e-09 38.5 0.1 1.9 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Fer4_7 PF12838.7 EST47847.1 - 2.2e-09 37.8 7.0 2.2e-09 37.8 7.0 3.0 3 0 0 3 3 3 1 4Fe-4S dicluster domain TPP_enzyme_C PF02775.21 EST47847.1 - 4.8e-09 36.2 0.0 1.1e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4_9 PF13187.6 EST47847.1 - 1.2e-08 34.9 3.0 1.2e-08 34.9 3.0 2.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 EST47847.1 - 2.8e-08 34.6 6.3 2.8e-08 34.6 6.3 2.6 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 EST47847.1 - 1.3e-05 25.2 10.3 1.3e-05 25.2 10.3 3.0 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4 PF00037.27 EST47847.1 - 1.6e-05 24.5 21.7 0.0012 18.6 3.7 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_21 PF14697.6 EST47847.1 - 1.8e-05 24.7 14.1 0.00077 19.5 14.1 3.0 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EST47847.1 - 4.9e-05 23.7 5.5 4.9e-05 23.7 5.5 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 EST47847.1 - 0.00068 19.6 21.2 0.024 14.7 3.4 3.5 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_17 PF13534.6 EST47847.1 - 0.00073 20.0 13.7 0.0017 18.9 8.9 2.8 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 EST47847.1 - 0.00077 19.4 3.3 0.00077 19.4 3.3 3.3 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_18 PF13746.6 EST47847.1 - 0.013 15.7 12.7 0.15 12.3 2.8 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 EST47847.1 - 0.014 15.9 16.2 0.18 12.4 1.9 3.6 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_3 PF12798.7 EST47847.1 - 0.037 15.0 22.3 1.2 10.3 7.9 3.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_15 PF13459.6 EST47847.1 - 0.2 12.4 6.0 2 9.2 0.6 2.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain EF-hand_1 PF00036.32 EST47850.1 - 2.7e-11 42.1 3.7 0.00011 21.5 0.5 4.3 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.6 EST47850.1 - 1.1e-09 37.4 8.7 0.00012 21.3 0.1 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EST47850.1 - 2.1e-08 33.4 5.5 0.0064 16.3 0.3 4.0 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 EST47850.1 - 9.7e-07 29.2 5.1 0.089 13.3 2.7 3.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EST47850.1 - 4.5e-06 26.4 3.9 0.039 13.8 0.2 4.1 4 1 0 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EST47850.1 - 0.15 12.4 0.6 2 8.8 0.1 2.1 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Cation_efflux PF01545.21 EST47851.1 - 1.8e-54 184.5 0.1 2.5e-54 184.0 0.1 1.2 1 0 0 1 1 1 1 Cation efflux family DUF2564 PF10819.8 EST47851.1 - 0.005 17.2 0.5 0.013 15.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2564) DUF4366 PF14283.6 EST47851.1 - 0.043 13.9 1.4 0.23 11.5 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Zip PF02535.22 EST47851.1 - 0.075 12.2 21.0 0.16 11.1 21.0 1.5 1 1 0 1 1 1 0 ZIP Zinc transporter RNA_pol_Rbc25 PF08292.12 EST47852.1 - 2e-10 41.0 1.2 1.5e-06 28.5 0.2 2.3 1 1 1 2 2 2 2 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 EST47852.1 - 1.1e-08 35.3 0.0 1.6e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Late_protein_L1 PF00500.18 EST47852.1 - 0.0047 15.8 0.1 0.0056 15.6 0.1 1.1 1 0 0 1 1 1 1 L1 (late) protein Dirigent PF03018.14 EST47852.1 - 0.12 12.1 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Dirigent-like protein Annexin PF00191.20 EST47854.1 - 0.0041 17.2 1.1 0.0075 16.3 1.1 1.5 1 0 0 1 1 1 1 Annexin p47_phox_C PF08944.11 EST47855.1 - 0.16 11.4 0.6 0.31 10.5 0.6 1.5 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain Ribosomal_L20 PF00453.18 EST47858.1 - 0.087 12.9 0.7 9 6.4 0.2 2.4 1 1 0 2 2 2 0 Ribosomal protein L20 zf-CHY PF05495.12 EST47859.1 - 6.9e-12 45.7 14.2 6.9e-12 45.7 14.2 1.6 2 0 0 2 2 2 1 CHY zinc finger Annexin PF00191.20 EST47860.1 - 7e-45 151.0 4.2 8e-15 54.7 0.1 5.1 5 0 0 5 5 5 5 Annexin Proteasome PF00227.26 EST47861.1 - 1.5e-16 60.5 0.0 2.5e-15 56.5 0.0 2.1 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EST47861.1 - 3.8e-08 32.9 0.0 3.8e-08 32.9 0.0 2.6 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature Syndecan PF01034.20 EST47862.1 - 0.15 12.0 0.4 0.26 11.2 0.4 1.3 1 0 0 1 1 1 0 Syndecan domain DUF1180 PF06679.12 EST47867.1 - 4 7.8 6.2 0.39 11.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) RFX1_trans_act PF04589.13 EST47868.1 - 0.022 15.0 1.4 0.026 14.7 0.2 1.7 2 0 0 2 2 2 0 RFX1 transcription activation region Fijivirus_P9-2 PF06837.11 EST47868.1 - 0.49 9.8 7.7 0.5 9.8 0.9 2.1 2 0 0 2 2 2 0 Fijivirus P9-2 protein CCB1 PF12046.8 EST47870.1 - 0.0091 15.4 1.3 0.0091 15.4 1.3 2.3 2 0 0 2 2 2 1 Cofactor assembly of complex C subunit B KASH_CCD PF14662.6 EST47872.1 - 0.00034 20.5 13.3 0.00055 19.8 13.3 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Macoilin PF09726.9 EST47872.1 - 0.037 12.6 7.9 0.044 12.3 7.9 1.1 1 0 0 1 1 1 0 Macoilin family pEK499_p136 PF18736.1 EST47872.1 - 0.061 12.9 1.6 0.14 11.8 1.4 1.8 1 1 0 1 1 1 0 HEPN pEK499 p136 DivIC PF04977.15 EST47872.1 - 0.089 12.6 19.4 0.038 13.8 7.1 2.9 2 1 1 3 3 3 0 Septum formation initiator ATG16 PF08614.11 EST47872.1 - 0.2 11.8 16.1 0.087 13.0 13.8 1.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CENP-H PF05837.12 EST47872.1 - 0.32 11.4 10.7 0.77 10.2 10.7 1.7 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Halogen_Hydrol PF10112.9 EST47872.1 - 0.84 9.6 6.4 3.8 7.5 1.9 2.8 2 1 1 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein SOGA PF11365.8 EST47872.1 - 2.6 9.2 13.1 3.4 8.9 10.5 2.3 2 1 1 3 3 2 0 Protein SOGA FapA PF03961.13 EST47872.1 - 2.8 6.5 11.3 5.1 5.6 11.3 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A SlyX PF04102.12 EST47872.1 - 6.3 7.5 10.8 38 5.0 7.9 3.3 3 1 1 4 4 4 0 SlyX DUF5398 PF17376.2 EST47872.1 - 6.6 7.4 9.3 8.1 7.1 4.0 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5398) ORF_12_N PF18042.1 EST47873.1 - 0.086 13.3 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 ORF 12 gene product N-terminal ASL_C2 PF14698.6 EST47873.1 - 0.19 12.5 0.1 0.48 11.2 0.1 1.8 1 1 0 1 1 1 0 Argininosuccinate lyase C-terminal Pyr_redox_2 PF07992.14 EST47874.1 - 1.4e-13 50.7 0.0 9.6e-08 31.6 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EST47874.1 - 2.9e-05 23.5 1.1 0.15 11.3 0.0 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EST47874.1 - 0.00022 20.4 0.4 0.028 13.5 0.1 2.3 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EST47874.1 - 0.00032 19.9 0.4 0.013 14.6 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EST47874.1 - 0.0034 17.0 2.2 0.23 11.0 4.1 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EST47874.1 - 0.0083 15.4 0.1 0.018 14.3 0.1 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 EST47874.1 - 0.011 14.5 0.3 0.13 10.9 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.7 EST47874.1 - 0.017 14.5 0.6 0.03 13.7 0.6 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EST47874.1 - 0.1 12.8 0.6 0.27 11.5 0.6 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EST47874.1 - 0.17 12.5 0.9 0.76 10.4 0.3 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Phage_TAC_6 PF09550.10 EST47875.1 - 0.022 15.2 0.1 0.036 14.5 0.1 1.4 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC PHO4 PF01384.20 EST47875.1 - 0.033 13.2 0.6 0.035 13.1 0.6 1.1 1 0 0 1 1 1 0 Phosphate transporter family Cbl_N3 PF02762.14 EST47875.1 - 0.046 13.6 0.3 6 6.8 0.2 2.3 1 1 1 2 2 2 0 CBL proto-oncogene N-terminus, SH2-like domain PAS_7 PF12860.7 EST47879.1 - 0.0006 20.0 0.0 0.00069 19.8 0.0 1.1 1 0 0 1 1 1 1 PAS fold Nrap_D5 PF17406.2 EST47880.1 - 0.052 13.3 0.2 0.2 11.4 0.2 2.0 1 0 0 1 1 1 0 Nrap protein PAP/OAS1-like domain 5 AhpC-TSA PF00578.21 EST47880.1 - 0.89 9.5 4.0 0.85 9.6 0.1 2.8 3 0 0 3 3 3 0 AhpC/TSA family zf-RING_9 PF13901.6 EST47881.1 - 0.031 14.3 3.4 0.028 14.4 2.3 1.4 1 1 0 1 1 1 0 Putative zinc-RING and/or ribbon CBM77 PF18283.1 EST47881.1 - 0.033 14.5 1.5 0.12 12.7 0.4 2.3 1 1 1 2 2 2 0 Carbohydrate binding module 77 NusA_N PF08529.11 EST47881.1 - 0.043 14.2 2.9 0.06 13.7 1.0 2.0 2 0 0 2 2 2 0 NusA N-terminal domain GMC_oxred_N PF00732.19 EST47882.1 - 0.0019 17.6 0.1 0.0029 17.0 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase BRCT PF00533.26 EST47882.1 - 0.12 12.8 0.1 0.33 11.4 0.1 1.8 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain NAD_binding_8 PF13450.6 EST47883.1 - 3.9e-11 43.0 0.1 4.8e-11 42.7 0.1 1.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EST47883.1 - 1e-09 38.0 0.0 1.1e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EST47883.1 - 2.8e-05 23.5 0.0 2.9e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EST47883.1 - 6e-05 22.8 0.0 6e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EST47883.1 - 9.2e-05 21.8 0.0 0.00012 21.4 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 EST47883.1 - 0.00017 21.1 0.0 0.00018 21.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EST47883.1 - 0.00026 19.8 0.3 0.00036 19.4 0.3 1.1 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 EST47883.1 - 0.0013 18.0 0.2 0.0018 17.6 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 EST47883.1 - 0.0014 18.0 0.0 0.0015 17.9 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase GDI PF00996.18 EST47883.1 - 0.0055 15.3 0.1 0.0062 15.1 0.1 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor Pyr_redox_3 PF13738.6 EST47883.1 - 0.02 14.2 0.1 0.023 14.0 0.1 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GBP_PSP PF02425.15 EST47883.1 - 0.027 14.1 1.4 0.049 13.3 1.4 1.3 1 0 0 1 1 1 0 Paralytic/GBP/PSP peptide GIDA PF01134.22 EST47883.1 - 0.054 12.6 0.2 0.062 12.4 0.2 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Imm5 PF14423.6 EST47885.1 - 0.068 13.4 0.4 0.096 12.9 0.4 1.3 1 0 0 1 1 1 0 Immunity protein Imm5 PDE8 PF08629.10 EST47886.1 - 0.036 14.1 1.0 0.068 13.2 1.0 1.4 1 0 0 1 1 1 0 PDE8 phosphodiesterase MCR_gamma PF02240.16 EST47887.1 - 0.12 11.6 0.1 0.21 10.8 0.1 1.3 1 0 0 1 1 1 0 Methyl-coenzyme M reductase gamma subunit Myb_DNA-binding PF00249.31 EST47888.1 - 4.5e-07 29.9 0.7 4.5e-07 29.9 0.7 1.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST47888.1 - 0.0019 18.4 0.7 0.0025 18.0 0.2 1.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Zip PF02535.22 EST47889.1 - 7.1e-33 114.2 10.4 1.1e-32 113.6 10.4 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Phage_holin_3_3 PF16083.5 EST47889.1 - 0.2 11.8 4.2 0.26 11.4 0.1 2.9 3 0 0 3 3 3 0 LydA holin phage, holin superfamily III Glucokinase PF02685.16 EST47890.1 - 1.4e-14 53.8 0.0 2.9e-07 29.8 0.0 3.0 1 1 1 2 2 2 2 Glucokinase ROK PF00480.20 EST47890.1 - 2.9e-11 43.4 0.2 3.9e-11 43.0 0.2 1.2 1 0 0 1 1 1 1 ROK family MreB_Mbl PF06723.13 EST47890.1 - 0.0023 16.8 0.1 0.004 16.0 0.1 1.5 1 0 0 1 1 1 1 MreB/Mbl protein MutL PF13941.6 EST47890.1 - 0.018 13.7 0.0 0.65 8.5 0.0 2.3 2 0 0 2 2 2 0 MutL protein FtsA PF14450.6 EST47890.1 - 0.096 13.1 0.1 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 Cell division protein FtsA Sugar_tr PF00083.24 EST47891.1 - 6e-44 150.7 43.4 1.9e-33 116.0 16.3 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EST47891.1 - 4.2e-17 62.1 37.3 9.6e-11 41.2 12.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EST47891.1 - 4.9e-07 29.4 4.5 8.6e-07 28.6 4.5 1.4 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Kinesin PF00225.23 EST47893.1 - 8.6e-112 373.3 0.0 8.6e-112 373.3 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EST47893.1 - 5.1e-27 94.6 0.0 1.6e-26 93.0 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding BST2 PF16716.5 EST47893.1 - 0.012 16.2 0.6 0.012 16.2 0.6 3.8 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 HlyD_3 PF13437.6 EST47893.1 - 0.046 14.4 1.1 0.16 12.6 0.0 2.5 2 1 0 2 2 2 0 HlyD family secretion protein ssDBP PF17878.1 EST47893.1 - 0.092 13.0 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 Single-stranded DNA-binding protein LPP PF04728.13 EST47893.1 - 0.38 11.2 0.0 0.38 11.2 0.0 3.1 3 1 1 4 4 4 0 Lipoprotein leucine-zipper Peptidase_S46 PF10459.9 EST47893.1 - 1.1 7.9 20.4 0.097 11.3 15.3 1.7 1 1 1 2 2 2 0 Peptidase S46 AAA_22 PF13401.6 EST47893.1 - 1.4 9.2 4.4 6.3 7.1 0.0 3.0 2 1 1 3 3 3 0 AAA domain Kinesin_assoc PF16183.5 EST47893.1 - 4.4 7.4 14.0 2.8 8.1 10.2 2.4 1 1 1 2 2 2 0 Kinesin-associated HAD_2 PF13419.6 EST47898.1 - 2.7e-16 60.2 0.0 5.6e-16 59.1 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EST47898.1 - 1.4e-10 41.8 0.2 7.3e-08 33.0 0.2 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EST47898.1 - 5.6e-05 23.6 0.3 0.0001 22.8 0.3 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EST47898.1 - 0.0044 16.4 0.0 0.0068 15.8 0.0 1.3 1 0 0 1 1 1 1 Putative Phosphatase Hydrolase_6 PF13344.6 EST47898.1 - 0.019 15.1 0.0 0.08 13.1 0.0 2.0 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase HAD_SAK_2 PF18143.1 EST47898.1 - 0.061 13.6 0.1 0.29 11.4 0.1 1.9 1 1 0 1 1 1 0 HAD domain in Swiss Army Knife RNA repair proteins RabGAP-TBC PF00566.18 EST47900.1 - 1.7e-05 24.6 3.0 2.4e-05 24.1 3.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CagS PF16707.5 EST47900.1 - 0.052 13.6 0.1 0.081 12.9 0.1 1.2 1 0 0 1 1 1 0 Cag pathogenicity island protein S of Helicobacter pylori DUF1816 PF08846.10 EST47902.1 - 0.042 13.9 2.2 0.061 13.3 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1816) Cue1_U7BR PF18499.1 EST47903.1 - 0.00055 19.9 0.1 0.00075 19.5 0.1 1.3 1 0 0 1 1 1 1 Ubc7p-binding region of Cue1 Glyco_hydro_77 PF02446.17 EST47905.1 - 1.5e-122 409.8 2.4 2e-122 409.4 2.4 1.1 1 0 0 1 1 1 1 4-alpha-glucanotransferase CBM_20 PF00686.19 EST47905.1 - 0.00021 21.1 0.2 0.042 13.8 0.0 2.6 2 0 0 2 2 2 2 Starch binding domain AMPK1_CBM PF16561.5 EST47905.1 - 0.063 13.5 0.2 0.36 11.1 0.1 2.4 3 0 0 3 3 3 0 Glycogen recognition site of AMP-activated protein kinase MecA PF05389.12 EST47905.1 - 0.074 12.7 0.1 0.19 11.3 0.0 1.7 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) DUF4926 PF16277.5 EST47907.1 - 0.053 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4926) PHD_2 PF13831.6 EST47909.1 - 0.061 12.9 0.7 0.12 11.9 0.7 1.5 1 0 0 1 1 1 0 PHD-finger KxDL PF10241.9 EST47911.1 - 0.0092 16.2 2.3 0.0092 16.2 2.3 4.1 3 1 1 4 4 3 2 Uncharacterized conserved protein GAS PF13851.6 EST47911.1 - 0.034 13.5 32.7 0.64 9.3 9.3 3.3 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding HALZ PF02183.18 EST47911.1 - 0.048 13.9 0.9 0.048 13.9 0.9 4.6 3 2 1 4 4 4 0 Homeobox associated leucine zipper DUF4407 PF14362.6 EST47911.1 - 0.081 12.3 27.1 0.084 12.2 13.9 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 EST47911.1 - 0.21 12.1 36.8 2.4 8.7 25.7 3.7 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF641 PF04859.12 EST47911.1 - 0.22 11.9 17.1 0.39 11.1 0.4 3.2 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) DUF4695 PF15766.5 EST47911.1 - 0.27 11.5 10.5 0.033 14.4 4.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4695) DUF948 PF06103.11 EST47911.1 - 0.89 9.9 8.3 5.8 7.2 0.1 3.7 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) PRKG1_interact PF15898.5 EST47911.1 - 2.5 9.0 26.1 4 8.4 9.4 4.0 1 1 3 4 4 4 0 cGMP-dependent protein kinase interacting domain DUF4600 PF15372.6 EST47911.1 - 3.6 8.0 22.6 1.2 9.6 8.7 3.3 2 1 0 3 3 3 0 Domain of unknown function (DUF4600) BBP1_C PF15272.6 EST47911.1 - 4.2 7.2 24.5 0.029 14.2 5.0 3.6 2 1 2 4 4 4 0 Spindle pole body component BBP1, C-terminal DUF1515 PF07439.11 EST47911.1 - 4.3 7.4 8.2 21 5.2 2.6 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) DEDD_Tnp_IS110 PF01548.17 EST47911.1 - 4.3 7.2 9.5 7.1 6.5 3.3 3.3 2 2 0 2 2 2 0 Transposase Occludin_ELL PF07303.13 EST47911.1 - 7.8 7.3 20.3 25 5.7 1.4 4.3 2 1 1 4 4 4 0 Occludin homology domain HIP1_clath_bdg PF16515.5 EST47911.1 - 9.9 6.9 36.3 11 6.7 2.1 4.1 2 1 2 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 gag_pre-integrs PF13976.6 EST47914.1 - 0.0055 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain RabGAP-TBC PF00566.18 EST47915.1 - 0.00089 19.0 0.1 0.0013 18.4 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Asparaginase PF00710.20 EST47916.1 - 5.5e-25 88.0 0.0 8.5e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 EST47916.1 - 3.4e-20 72.4 0.0 4.6e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain DUF3587 PF12132.8 EST47918.1 - 0.055 12.9 0.3 0.13 11.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3587) pXO2-34 PF17362.2 EST47918.1 - 0.074 12.9 0.2 0.14 12.0 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function dNK PF01712.19 EST47919.1 - 8.9e-36 123.7 0.1 1e-35 123.4 0.1 1.0 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_28 PF13521.6 EST47919.1 - 1.8e-07 31.5 0.0 2.1e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EST47919.1 - 3.2e-06 26.9 0.1 9.7e-06 25.4 0.1 1.8 1 1 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.6 EST47919.1 - 8.6e-06 26.0 0.0 1.4e-05 25.3 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EST47919.1 - 0.0016 19.0 0.0 0.0086 16.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EST47919.1 - 0.003 18.0 0.0 0.28 11.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF4085 PF13315.6 EST47919.1 - 0.05 13.2 0.1 0.098 12.3 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4085) TsaE PF02367.17 EST47919.1 - 0.057 13.4 0.0 0.082 12.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Dynamin_N PF00350.23 EST47919.1 - 0.11 12.6 0.0 0.13 12.3 0.0 1.3 1 1 0 1 1 1 0 Dynamin family Zeta_toxin PF06414.12 EST47919.1 - 0.13 11.6 0.0 0.37 10.0 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin dNK PF01712.19 EST47920.1 - 8.9e-36 123.7 0.1 1e-35 123.4 0.1 1.0 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_28 PF13521.6 EST47920.1 - 1.8e-07 31.5 0.0 2.1e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EST47920.1 - 3.2e-06 26.9 0.1 9.7e-06 25.4 0.1 1.8 1 1 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.6 EST47920.1 - 8.6e-06 26.0 0.0 1.4e-05 25.3 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EST47920.1 - 0.0016 19.0 0.0 0.0086 16.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EST47920.1 - 0.003 18.0 0.0 0.28 11.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF4085 PF13315.6 EST47920.1 - 0.05 13.2 0.1 0.098 12.3 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4085) TsaE PF02367.17 EST47920.1 - 0.057 13.4 0.0 0.082 12.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Dynamin_N PF00350.23 EST47920.1 - 0.11 12.6 0.0 0.13 12.3 0.0 1.3 1 1 0 1 1 1 0 Dynamin family Zeta_toxin PF06414.12 EST47920.1 - 0.13 11.6 0.0 0.37 10.0 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin DUF3587 PF12132.8 EST47921.1 - 0.055 12.9 0.3 0.13 11.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3587) pXO2-34 PF17362.2 EST47921.1 - 0.074 12.9 0.2 0.14 12.0 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function CCDC24 PF15669.5 EST47923.1 - 0.0082 16.0 1.5 0.011 15.6 1.1 1.3 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 24 family Myb_DNA-binding PF00249.31 EST47924.1 - 3e-08 33.7 0.3 3.8e-08 33.4 0.3 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EST47924.1 - 1.3e-05 25.3 0.2 1.6e-05 25.0 0.2 1.1 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_6 PF13921.6 EST47924.1 - 0.00023 21.3 0.1 0.00029 21.0 0.1 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST47924.1 - 0.0011 18.8 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 EST47927.1 - 1.1e-05 25.6 0.5 1.4e-05 25.2 0.5 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EST47927.1 - 3e-05 24.1 0.3 3.7e-05 23.8 0.3 1.1 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_6 PF13921.6 EST47927.1 - 0.0054 17.0 0.1 0.0068 16.6 0.1 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST47927.1 - 0.051 13.5 0.0 0.053 13.4 0.0 1.1 1 0 0 1 1 1 0 Myb DNA-binding like BOP1NT PF08145.12 EST47930.1 - 7e-20 72.0 17.8 2.8e-14 53.7 3.3 2.5 2 1 1 3 3 3 2 BOP1NT (NUC169) domain WD40 PF00400.32 EST47930.1 - 8.7e-20 70.7 2.0 2.4e-05 25.0 0.0 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EST47930.1 - 1.1e-07 32.1 0.1 0.001 19.3 0.0 3.9 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PDDEXK_9 PF08011.11 EST47930.1 - 3.4 7.6 5.7 1.1 9.1 1.1 2.5 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily Myb_DNA-binding PF00249.31 EST47932.1 - 3e-08 33.7 0.3 3.8e-08 33.4 0.3 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EST47932.1 - 1.3e-05 25.3 0.2 1.6e-05 25.0 0.2 1.1 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_6 PF13921.6 EST47932.1 - 0.00023 21.3 0.1 0.00029 21.0 0.1 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST47932.1 - 0.0011 18.8 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Myb DNA-binding like Sulfatase PF00884.23 EST47934.1 - 8.8e-15 54.9 1.0 1.2e-14 54.5 1.0 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EST47934.1 - 0.033 13.8 3.7 0.27 10.8 0.1 2.3 1 1 1 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase TCO89 PF10452.9 EST47937.1 - 0.0023 17.0 0.7 0.0031 16.6 0.7 1.1 1 0 0 1 1 1 1 TORC1 subunit TCO89 Aminotran_1_2 PF00155.21 EST47938.1 - 2.7e-34 118.9 0.0 3.2e-34 118.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EST47938.1 - 0.0011 18.1 0.0 0.0048 15.9 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V SPOB_ab PF14682.6 EST47938.1 - 0.0036 17.4 0.1 0.011 15.8 0.0 1.9 2 0 0 2 2 2 1 Sporulation initiation phospho-transferase B, C-terminal Beta_elim_lyase PF01212.21 EST47938.1 - 0.0051 16.1 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EST47938.1 - 0.019 13.5 0.0 0.032 12.8 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme COX7B PF05392.11 EST47939.1 - 0.1 12.3 0.7 1.9 8.2 0.3 2.1 2 0 0 2 2 2 0 Cytochrome C oxidase chain VIIB Sulfatase PF00884.23 EST47940.1 - 9.3e-15 54.8 1.0 1.2e-14 54.4 1.0 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EST47940.1 - 0.036 13.7 3.7 0.32 10.5 0.1 2.3 1 1 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF2382 PF09557.10 EST47941.1 - 0.25 11.6 7.6 0.19 12.0 2.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2382) PapC_N PF13954.6 EST47941.1 - 0.41 10.6 4.3 1.4 8.9 0.7 2.6 2 0 0 2 2 2 0 PapC N-terminal domain VSP PF03302.13 EST47942.1 - 6.5e-09 35.1 84.8 2.4e-05 23.4 38.8 4.1 1 1 1 2 2 2 2 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST47942.1 - 0.0058 16.8 88.9 0.86 9.8 7.9 6.6 1 1 5 6 6 6 6 Furin-like repeat, cysteine-rich Prok-RING_2 PF14445.6 EST47942.1 - 0.022 14.9 4.3 0.022 14.9 4.3 6.5 2 1 4 6 6 6 0 Prokaryotic RING finger family 2 Aldose_epim PF01263.20 EST47943.1 - 5.5e-11 42.3 0.1 6e-11 42.2 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase TMEMspv1-c74-12 PF11044.8 EST47944.1 - 0.0043 17.0 2.3 0.011 15.7 2.3 1.7 1 0 0 1 1 1 1 Plectrovirus spv1-c74 ORF 12 transmembrane protein Cadherin-like PF12733.7 EST47944.1 - 0.18 12.4 6.4 0.47 11.0 1.6 3.2 3 1 0 3 3 3 0 Cadherin-like beta sandwich domain Aldose_epim PF01263.20 EST47945.1 - 8.9e-58 196.0 0.5 1e-57 195.8 0.5 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Sugar_tr PF00083.24 EST47946.1 - 1.4e-58 198.9 39.3 1.2e-37 129.9 16.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EST47946.1 - 1.2e-21 77.1 54.8 1.1e-18 67.3 34.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EST47946.1 - 9.6e-05 21.8 17.6 0.00016 21.1 17.6 1.3 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB HSP90 PF00183.18 EST47947.1 - 3.3e-194 646.6 21.0 4.3e-194 646.2 21.0 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 EST47947.1 - 7.5e-12 45.7 0.0 1.8e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EST47947.1 - 2.4e-09 37.1 1.3 3.9e-09 36.4 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PQ-loop PF04193.14 EST47948.1 - 3.4e-28 97.2 13.5 1.6e-14 53.4 5.2 2.5 2 0 0 2 2 2 2 PQ loop repeat Ins_allergen_rp PF06757.13 EST47949.1 - 0.039 13.9 0.1 0.088 12.8 0.1 1.6 1 0 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification VSP PF03302.13 EST47954.1 - 3.4e-06 26.2 59.6 2.3e-05 23.4 30.1 7.9 1 1 6 7 7 7 6 Giardia variant-specific surface protein VSP PF03302.13 EST47956.1 - 0.00026 20.0 35.7 0.00026 20.0 35.7 9.8 1 1 8 9 9 9 4 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST47956.1 - 0.0074 16.4 25.1 0.0074 16.4 25.1 14.4 1 1 14 15 15 15 3 Furin-like repeat, cysteine-rich PP2C PF00481.21 EST47958.1 - 3e-57 194.2 0.0 5e-57 193.5 0.0 1.3 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 EST47958.1 - 2.8e-06 27.1 0.0 5.6e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C VSP PF03302.13 EST47960.1 - 1.5e-12 47.1 204.7 1.4e-05 24.1 22.4 7.7 1 1 6 8 8 8 6 Giardia variant-specific surface protein Orf78 PF06024.12 EST47960.1 - 0.00028 21.1 0.2 0.0005 20.3 0.2 1.3 1 0 0 1 1 1 1 Orf78 (ac78) Furin-like_2 PF15913.5 EST47960.1 - 0.0021 18.2 15.5 0.0021 18.2 15.5 12.2 1 1 12 13 13 13 6 Furin-like repeat, cysteine-rich DUF3377 PF11857.8 EST47960.1 - 0.0047 16.8 0.2 0.0084 16.0 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) Insulin_TMD PF17870.1 EST47960.1 - 0.033 14.3 5.9 0.058 13.5 5.9 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF4366 PF14283.6 EST47960.1 - 0.082 13.0 0.3 0.26 11.3 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) S1FA PF04689.13 EST47960.1 - 0.13 12.4 0.1 0.24 11.5 0.1 1.4 1 0 0 1 1 1 0 DNA binding protein S1FA VSP PF03302.13 EST47964.1 - 0.00056 18.9 2.3 0.00056 18.9 2.3 3.1 1 1 2 3 3 3 2 Giardia variant-specific surface protein Insulin_TMD PF17870.1 EST47964.1 - 0.018 15.1 0.1 0.03 14.4 0.1 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment T4SS_CagC PF16943.5 EST47964.1 - 0.043 14.0 0.2 0.072 13.3 0.2 1.3 1 0 0 1 1 1 0 Cag pathogenicity island, type IV secretory system DUF5316 PF17247.2 EST47964.1 - 0.36 10.9 5.2 0.56 10.3 4.4 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5316) DUF1132 PF06575.12 EST47966.1 - 0.0049 17.2 0.9 0.044 14.2 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1132) LBP_BPI_CETP PF01273.25 EST47966.1 - 0.0055 16.3 1.1 0.012 15.2 1.1 1.6 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain DUF2442 PF10387.9 EST47966.1 - 0.093 13.0 0.2 1.4 9.3 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2442) DUF4968 PF16338.5 EST47966.1 - 0.13 12.6 2.1 11 6.5 2.1 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4968) VSP PF03302.13 EST47967.1 - 2.3e-21 76.1 283.0 6.1e-07 28.6 32.0 10.4 1 1 8 10 10 10 9 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST47967.1 - 1e-06 28.9 273.7 0.0006 19.9 27.5 13.8 1 1 13 14 14 14 8 Furin-like repeat, cysteine-rich Pepdidase_M14_N PF18027.1 EST47971.1 - 0.0014 19.0 1.0 0.0089 16.4 0.1 2.7 1 1 1 2 2 2 1 Cytosolic carboxypeptidase N-terminal domain Peptidase_M14 PF00246.24 EST47971.1 - 0.0024 17.7 0.0 0.026 14.3 0.0 2.3 1 1 0 1 1 1 1 Zinc carboxypeptidase TRAPP PF04051.16 EST47974.1 - 2.5e-14 53.2 0.0 3.1e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component LRR_8 PF13855.6 EST47975.1 - 0.4 10.5 1.4 1.1e+02 2.7 0.0 4.8 6 0 0 6 6 6 0 Leucine rich repeat Adhesin_P1 PF03257.13 EST47976.1 - 0.07 13.7 0.8 0.09 13.3 0.8 1.3 1 0 0 1 1 1 0 Mycoplasma adhesin P1 Pribosyltran PF00156.27 EST47977.1 - 6e-12 45.4 0.1 8.4e-12 44.9 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EST47977.1 - 0.033 13.6 0.0 0.041 13.3 0.0 1.1 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase ASXH PF13919.6 EST47979.1 - 0.12 12.4 0.5 0.37 10.8 0.1 2.0 2 0 0 2 2 2 0 Asx homology domain CBM32 PF18344.1 EST47980.1 - 0.092 12.6 0.2 0.54 10.1 0.0 2.3 2 0 0 2 2 2 0 Carbohydrate binding module family 32 Methyltransf_31 PF13847.6 EST47980.1 - 0.89 9.3 3.7 1.8 8.4 3.1 1.7 1 1 1 2 2 2 0 Methyltransferase domain DUF4897 PF16238.5 EST47983.1 - 0.065 13.1 1.4 0.22 11.4 1.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4897) TagA PF12561.8 EST47983.1 - 0.12 12.8 0.4 0.63 10.5 0.4 2.4 1 0 0 1 1 1 0 ToxR activated gene A lipoprotein domain SIR2 PF02146.17 EST47984.1 - 3.4e-39 134.6 0.0 5.4e-39 133.9 0.0 1.3 1 0 0 1 1 1 1 Sir2 family LRR_4 PF12799.7 EST47985.1 - 0.029 14.8 19.9 0.22 12.0 1.6 4.5 2 2 1 3 3 3 0 Leucine Rich repeats (2 copies) DUF2484 PF10658.9 EST47986.1 - 0.045 14.1 0.2 0.045 14.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2484) FERM_N PF09379.10 EST47989.1 - 0.068 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 FERM N-terminal domain DndE PF08870.11 EST47989.1 - 0.078 13.2 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 DNA sulphur modification protein DndE XTBD PF11952.8 EST47989.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.6 1 1 0 1 1 1 0 XRN-Two Binding Domain, XTBD zf-HIT PF04438.16 EST47990.1 - 0.027 14.3 18.9 0.048 13.5 18.9 1.4 1 0 0 1 1 1 0 HIT zinc finger DUF1007 PF06226.13 EST47991.1 - 5.1 7.0 11.1 0.36 10.8 4.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1007) DUF928 PF06051.12 EST47992.1 - 0.042 13.7 0.1 0.079 12.8 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF928) Macro PF01661.21 EST47993.1 - 6.6e-35 119.7 0.4 1e-34 119.1 0.1 1.4 2 0 0 2 2 2 1 Macro domain ILVD_EDD PF00920.21 EST47993.1 - 0.054 12.1 0.1 0.063 11.9 0.1 1.1 1 0 0 1 1 1 0 Dehydratase family zf-CHY PF05495.12 EST47996.1 - 1.7e-07 31.6 15.6 3e-07 30.8 15.3 1.5 1 1 1 2 2 2 1 CHY zinc finger zinc-ribbons_6 PF07191.12 EST47996.1 - 4 7.5 18.0 49 4.0 18.2 2.3 1 1 1 2 2 2 0 zinc-ribbons UPF0004 PF00919.20 EST47997.1 - 0.033 14.3 0.1 0.064 13.3 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein family UPF0004 DUF512 PF04459.12 EST47997.1 - 0.049 12.9 0.0 0.058 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF512) HMG_box PF00505.19 EST48000.1 - 6.9e-07 29.6 15.1 1.6e-05 25.2 4.1 3.1 1 1 2 3 3 3 2 HMG (high mobility group) box DHC PF09626.10 EST48000.1 - 0.11 13.4 3.6 0.13 13.2 2.8 1.5 1 1 0 1 1 1 0 Dihaem cytochrome c HMG_box_2 PF09011.10 EST48000.1 - 3.7 8.2 14.1 0.44 11.2 3.5 3.3 2 2 0 2 2 2 0 HMG-box domain PEX-1N PF09262.11 EST48002.1 - 0.083 13.3 0.1 0.14 12.6 0.1 1.3 1 0 0 1 1 1 0 Peroxisome biogenesis factor 1, N-terminal SH PF01445.17 EST48005.1 - 1.5 8.9 4.7 0.97 9.5 1.5 2.3 2 1 1 3 3 3 0 Viral small hydrophobic protein Arf PF00025.21 EST48009.1 - 1.1e-58 197.5 0.1 1.2e-58 197.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EST48009.1 - 1.8e-14 53.7 0.9 4.5e-10 39.2 0.1 2.5 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EST48009.1 - 4.8e-12 45.8 0.0 5.8e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EST48009.1 - 1.6e-11 44.0 0.1 2e-11 43.7 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EST48009.1 - 3.2e-11 43.5 0.0 4.4e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EST48009.1 - 6.6e-08 32.6 0.0 9.8e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EST48009.1 - 9.9e-08 31.6 0.0 1e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA PF00004.29 EST48009.1 - 0.017 15.5 0.0 0.024 15.1 0.0 1.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 EST48009.1 - 0.045 13.3 0.4 0.1 12.2 0.4 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.27 EST48009.1 - 0.066 13.7 0.2 0.091 13.3 0.2 1.5 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.9 EST48009.1 - 0.14 11.9 0.1 0.54 10.0 0.1 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MeaB PF03308.16 EST48009.1 - 0.16 10.9 0.1 0.31 10.0 0.0 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 EST48009.1 - 0.3 11.6 1.2 0.4 11.1 0.7 1.5 1 1 0 1 1 1 0 AAA domain DrsE PF02635.15 EST48010.1 - 0.13 12.7 1.3 0.23 11.9 0.4 1.8 1 1 1 2 2 2 0 DsrE/DsrF-like family RNA_pol_Rpb2_4 PF04566.13 EST48010.1 - 1.3 9.4 4.0 6.7 7.1 0.2 2.7 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 4 Ank_2 PF12796.7 EST48011.1 - 2.6e-14 53.6 0.0 1.3e-10 41.7 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EST48011.1 - 2.5e-07 30.9 2.5 0.0019 18.6 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EST48011.1 - 5.8e-07 29.3 1.0 0.03 14.9 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EST48011.1 - 8.7e-07 29.1 0.4 0.011 16.1 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EST48011.1 - 4.6e-06 27.1 0.2 6e-05 23.5 0.2 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) HALZ PF02183.18 EST48014.1 - 0.036 14.3 1.7 0.44 10.8 0.2 3.4 2 1 0 2 2 2 0 Homeobox associated leucine zipper YueH PF14166.6 EST48014.1 - 0.051 13.4 0.3 0.22 11.4 0.1 2.1 2 0 0 2 2 2 0 YueH-like protein Spc7 PF08317.11 EST48014.1 - 8.4 5.2 12.6 21 3.8 6.4 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein DICT PF10069.9 EST48015.1 - 0.0092 15.7 0.1 0.01 15.6 0.1 1.2 1 0 0 1 1 1 1 Sensory domain in DIguanylate Cyclases and Two-component system NS3_envE PF02723.14 EST48016.1 - 0.097 12.8 0.9 0.097 12.8 0.9 1.9 2 0 0 2 2 2 0 Non-structural protein NS3/Small envelope protein E TMEM65 PF10507.9 EST48016.1 - 0.18 11.8 1.7 0.31 11.0 1.5 1.5 1 1 0 1 1 1 0 Transmembrane protein 65 YccF PF03733.13 EST48016.1 - 0.28 11.9 4.5 7.7 7.3 0.2 2.2 2 0 0 2 2 2 0 Inner membrane component domain NifU_N PF01592.16 EST48017.1 - 4e-46 156.3 0.5 4.7e-46 156.1 0.5 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain Ribosomal_L22 PF00237.19 EST48017.1 - 0.073 13.3 0.3 0.12 12.6 0.3 1.3 1 0 0 1 1 1 0 Ribosomal protein L22p/L17e DICT PF10069.9 EST48018.1 - 0.0092 15.7 0.1 0.01 15.6 0.1 1.2 1 0 0 1 1 1 1 Sensory domain in DIguanylate Cyclases and Two-component system HALZ PF02183.18 EST48019.1 - 0.17 12.2 6.3 0.51 10.6 0.2 4.1 3 1 0 3 3 3 0 Homeobox associated leucine zipper DUF641 PF04859.12 EST48019.1 - 6.1 7.2 9.3 1.9 8.8 1.6 3.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Pkinase PF00069.25 EST48021.1 - 8.9e-50 169.5 0.0 1.2e-49 169.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST48021.1 - 4.6e-17 62.1 0.0 7.1e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EST48021.1 - 0.21 11.5 0.0 0.39 10.6 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Na_H_antiporter PF03553.14 EST48025.1 - 0.0094 15.2 0.7 0.013 14.8 0.7 1.1 1 0 0 1 1 1 1 Na+/H+ antiporter family CdiI PF07262.11 EST48026.1 - 0.0085 15.9 0.2 0.022 14.5 0.2 1.7 1 0 0 1 1 1 1 CDI immunity protein Fer2_4 PF13510.6 EST48026.1 - 8.9 6.4 6.4 22 5.2 5.6 2.1 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain AAA_30 PF13604.6 EST48028.1 - 0.063 13.0 0.0 0.3 10.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain zf-RRPl_C4 PF17026.5 EST48028.1 - 0.065 13.4 0.2 0.093 12.8 0.2 1.3 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type SRP54 PF00448.22 EST48028.1 - 0.095 12.3 0.7 5 6.7 0.1 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Sigma_1s PF02454.16 EST48030.1 - 0.0055 16.7 0.7 0.34 10.9 0.1 2.3 2 0 0 2 2 2 2 Sigma 1s protein EDS1_EP PF18117.1 EST48030.1 - 0.18 12.3 1.6 0.22 12.0 0.2 1.8 2 0 0 2 2 2 0 Enhanced disease susceptibility 1 protein EP domain RNA_pol_Rpb1_3 PF04983.18 EST48030.1 - 0.19 11.7 2.1 0.25 11.3 2.1 1.4 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 3 MTES_1575 PF18741.1 EST48033.1 - 0.0062 16.7 0.0 0.024 14.8 0.0 2.0 1 0 0 1 1 1 1 REase_MTES_1575 Peptidase_MA_2 PF13485.6 EST48034.1 - 0.08 12.6 1.0 0.12 12.0 1.0 1.2 1 0 0 1 1 1 0 Peptidase MA superfamily Rubrerythrin PF02915.17 EST48036.1 - 9.9e-26 90.8 0.3 1.3e-25 90.4 0.3 1.2 1 0 0 1 1 1 1 Rubrerythrin Ferritin PF00210.24 EST48036.1 - 3.4e-08 33.5 0.5 4.2e-07 30.0 0.5 2.0 1 1 0 1 1 1 1 Ferritin-like domain zf-UBP PF02148.19 EST48036.1 - 0.021 15.1 0.5 0.077 13.3 0.1 2.0 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein HalOD2 PF18547.1 EST48036.1 - 0.041 13.8 4.0 0.045 13.7 1.9 2.0 1 1 1 2 2 2 0 Halobacterial output domain 2 DUF3039 PF11238.8 EST48036.1 - 0.049 13.4 0.4 0.097 12.4 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3039) zinc_ribbon_11 PF11682.8 EST48036.1 - 0.053 13.5 0.0 0.074 13.1 0.0 1.3 1 0 0 1 1 1 0 Probable zinc-ribbon Vps36-NZF-N PF16988.5 EST48036.1 - 0.15 11.5 1.2 1.9 7.9 0.4 2.4 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 EST48036.1 - 0.22 11.6 2.7 1.7 8.7 0.4 2.3 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger OrfB_Zn_ribbon PF07282.11 EST48036.1 - 0.3 11.0 2.2 0.3 11.0 0.3 1.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Prim_Zn_Ribbon PF08273.12 EST48036.1 - 0.61 10.4 2.7 2.6 8.4 0.1 2.6 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase DUF1947 PF09183.10 EST48039.1 - 0.08 13.3 0.1 3.2 8.1 0.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1947) RNA_pol_Rpb2_6 PF00562.28 EST48040.1 - 2.5e-107 359.3 0.0 3.1e-106 355.7 0.0 2.6 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EST48040.1 - 9.1e-45 152.7 2.1 1.5e-44 151.9 2.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 EST48040.1 - 3.6e-28 97.8 0.2 2.4e-27 95.2 0.3 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 EST48040.1 - 2.7e-21 75.6 0.1 7.5e-21 74.2 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 EST48040.1 - 4.4e-17 62.0 0.0 1e-16 60.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 EST48040.1 - 7.8e-14 51.7 4.2 4.3e-12 46.1 4.2 2.5 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_5 PF04567.17 EST48040.1 - 0.0018 18.8 0.1 0.0067 17.0 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 DUF5100 PF17029.5 EST48041.1 - 0.00078 19.3 0.9 0.0014 18.4 0.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5100) FKBP_C PF00254.28 EST48043.1 - 2e-15 56.9 0.0 2.7e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase CAP PF00188.26 EST48045.1 - 2.3e-07 31.7 0.0 3.7e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family NB PF04159.13 EST48045.1 - 0.019 15.0 4.5 0.036 14.1 4.5 1.4 1 0 0 1 1 1 0 NB glycoprotein Shisa PF13908.6 EST48045.1 - 0.24 11.6 0.2 0.36 11.1 0.2 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator cEGF PF12662.7 EST48046.1 - 0.0099 15.8 1.7 0.0099 15.8 1.7 3.9 3 2 1 4 4 4 1 Complement Clr-like EGF-like Furin-like_2 PF15913.5 EST48046.1 - 0.023 14.8 29.6 0.035 14.2 15.1 2.2 1 1 1 2 2 2 0 Furin-like repeat, cysteine-rich DUF3149 PF11346.8 EST48046.1 - 0.25 11.0 3.3 0.4 10.3 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Peptidase_M22 PF00814.25 EST48047.1 - 4.1e-68 230.0 0.0 5e-68 229.7 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Pox_A11 PF05061.13 EST48047.1 - 0.045 13.0 0.0 0.062 12.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus A11 Protein Gal4_dimer PF03902.13 EST48049.1 - 0.044 14.0 0.0 0.34 11.1 0.1 2.3 2 0 0 2 2 2 0 Gal4-like dimerisation domain DnaB_2 PF07261.11 EST48050.1 - 0.011 15.4 0.1 0.053 13.3 0.1 2.2 1 0 0 1 1 1 0 Replication initiation and membrane attachment YabA PF06156.13 EST48050.1 - 0.018 15.7 4.8 0.018 15.7 4.8 3.4 2 1 1 3 3 3 0 Initiation control protein YabA DUF3574 PF12098.8 EST48050.1 - 0.049 13.4 0.6 0.19 11.5 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3574) HALZ PF02183.18 EST48050.1 - 0.059 13.6 0.9 0.059 13.6 0.9 3.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper CRR7 PF12095.8 EST48050.1 - 0.14 12.6 6.9 0.34 11.4 0.1 3.3 3 0 0 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 Cep57_CLD_2 PF14197.6 EST48050.1 - 3.3 7.9 9.7 19 5.4 0.3 3.4 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 DnaB_2 PF07261.11 EST48051.1 - 0.011 15.4 0.1 0.053 13.3 0.1 2.2 1 0 0 1 1 1 0 Replication initiation and membrane attachment YabA PF06156.13 EST48051.1 - 0.018 15.7 4.8 0.018 15.7 4.8 3.4 2 1 1 3 3 3 0 Initiation control protein YabA DUF3574 PF12098.8 EST48051.1 - 0.049 13.4 0.6 0.19 11.5 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3574) HALZ PF02183.18 EST48051.1 - 0.059 13.6 0.9 0.059 13.6 0.9 3.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper CRR7 PF12095.8 EST48051.1 - 0.14 12.6 6.9 0.34 11.4 0.1 3.3 3 0 0 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 Cep57_CLD_2 PF14197.6 EST48051.1 - 3.3 7.9 9.7 19 5.4 0.3 3.4 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 Sel1 PF08238.12 EST48052.1 - 0.091 13.5 0.9 27 5.6 0.1 3.8 3 0 0 3 3 3 0 Sel1 repeat DUF3717 PF12512.8 EST48053.1 - 0.075 12.9 0.0 0.15 11.9 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3717) PHD_like PF12910.7 EST48054.1 - 0.001 19.1 0.4 0.0044 17.0 0.0 2.0 2 0 0 2 2 2 1 Antitoxin of toxin-antitoxin, RelE / RelB, TA system DUF3232 PF11554.8 EST48055.1 - 0.12 12.7 0.2 0.12 12.7 0.2 2.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3232) PCRF PF03462.18 EST48055.1 - 8.8 6.1 15.9 3.1 7.6 4.0 3.2 2 1 2 4 4 4 0 PCRF domain FAD-SLDH PF12318.8 EST48056.1 - 0.0088 16.1 0.1 0.0091 16.1 0.1 1.0 1 0 0 1 1 1 1 Membrane bound FAD containing D-sorbitol dehydrogenase Amelin PF05111.12 EST48057.1 - 0.07 12.3 1.7 0.11 11.6 1.7 1.2 1 0 0 1 1 1 0 Ameloblastin precursor (Amelin) VSP PF03302.13 EST48061.1 - 4.4e-06 25.8 33.2 4.4e-06 25.8 33.2 2.4 1 1 1 2 2 2 1 Giardia variant-specific surface protein DUF4690 PF15756.5 EST48061.1 - 0.01 16.4 0.5 0.023 15.3 0.5 1.5 1 0 0 1 1 1 0 Small Novel Rich in Cartilage LRR_8 PF13855.6 EST48066.1 - 6.5e-08 32.2 0.1 0.0065 16.2 0.0 2.4 2 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EST48066.1 - 0.00016 22.0 0.0 1.1 9.8 0.0 3.3 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EST48066.1 - 0.0014 18.8 0.2 14 6.7 0.0 5.0 4 2 0 4 4 4 1 Leucine Rich Repeat LRRNT_2 PF08263.12 EST48066.1 - 0.011 16.0 5.3 0.025 14.9 5.3 1.7 1 1 0 1 1 1 0 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 EST48066.1 - 0.038 14.1 2.1 0.81 9.9 0.2 3.3 4 0 0 4 4 4 0 Leucine Rich repeat RNA_pol_Rpb2_5 PF04567.17 EST48068.1 - 0.053 14.1 2.5 0.14 12.7 2.5 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 5 DUF1068 PF06364.12 EST48068.1 - 0.18 11.6 6.7 2.7 7.8 5.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1068) Asp-B-Hydro_N PF05279.11 EST48068.1 - 1.2 9.2 12.7 1.6 8.8 12.7 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region RRM_1 PF00076.22 EST48069.1 - 8.2e-05 22.4 0.1 0.00015 21.6 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EST48069.1 - 0.029 14.5 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif LRR_8 PF13855.6 EST48070.1 - 6.5e-08 32.2 0.1 0.0065 16.2 0.0 2.4 2 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EST48070.1 - 0.00016 22.0 0.0 1.1 9.8 0.0 3.3 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EST48070.1 - 0.0014 18.8 0.2 14 6.7 0.0 5.0 4 2 0 4 4 4 1 Leucine Rich Repeat LRRNT_2 PF08263.12 EST48070.1 - 0.011 16.0 5.3 0.025 14.9 5.3 1.7 1 1 0 1 1 1 0 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 EST48070.1 - 0.038 14.1 2.1 0.81 9.9 0.2 3.3 4 0 0 4 4 4 0 Leucine Rich repeat FtsJ PF01728.19 EST48073.1 - 0.00051 20.2 0.2 0.0032 17.6 0.1 2.4 2 1 0 2 2 2 1 FtsJ-like methyltransferase Peptidase_C58 PF03543.14 EST48073.1 - 2.2 7.9 7.2 3.4 7.3 6.2 1.8 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen SHIPPO-rpt PF07004.12 EST48075.1 - 2.9e-25 88.0 61.9 0.002 19.0 0.8 11.6 12 0 0 12 12 12 10 Sperm-tail PG-rich repeat ECR1_N PF14382.6 EST48075.1 - 2.6e-08 33.5 14.7 0.76 9.6 0.1 8.2 8 1 1 9 9 9 3 Exosome complex exonuclease RRP4 N-terminal region BMF PF15185.6 EST48075.1 - 0.0011 18.7 0.0 0.047 13.4 0.0 2.3 2 0 0 2 2 2 1 Bcl-2-modifying factor, apoptosis Orbi_NS3 PF01616.16 EST48076.1 - 0.11 12.2 0.2 0.16 11.6 0.2 1.2 1 0 0 1 1 1 0 Orbivirus NS3 SHIPPO-rpt PF07004.12 EST48077.1 - 6.8e-13 48.9 44.8 0.021 15.7 0.1 11.2 11 1 0 11 11 11 6 Sperm-tail PG-rich repeat CTD PF12815.7 EST48077.1 - 1.5 9.4 9.9 0.31 11.6 2.2 3.2 3 1 0 3 3 3 0 Spt5 C-terminal nonapeptide repeat binding Spt4 MBG_2 PF18676.1 EST48077.1 - 9.1 7.0 8.2 3.5 8.3 0.1 4.0 4 1 0 5 5 5 0 MBG domain (YGX type) Laminin_G_2 PF02210.24 EST48078.1 - 0.11 13.1 0.1 0.17 12.4 0.1 1.3 1 0 0 1 1 1 0 Laminin G domain SHIPPO-rpt PF07004.12 EST48079.1 - 7.9e-13 48.7 33.8 0.017 16.0 0.6 6.3 6 0 0 6 6 6 5 Sperm-tail PG-rich repeat BTAD PF03704.17 EST48081.1 - 0.014 15.8 0.2 0.027 14.9 0.0 1.6 2 0 0 2 2 2 0 Bacterial transcriptional activator domain Sec16_C PF12931.7 EST48081.1 - 0.08 12.6 0.0 0.099 12.3 0.0 1.2 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 Myb_DNA-bind_6 PF13921.6 EST48085.1 - 1.4e-07 31.6 1.4 0.012 15.8 0.2 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EST48085.1 - 4.2e-06 26.9 0.0 0.077 13.2 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF5534 PF17686.1 EST48085.1 - 0.037 14.3 0.2 0.079 13.2 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5534) DUF1732 PF08340.11 EST48087.1 - 0.054 13.5 0.7 3.5 7.7 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1732) DJ-1_PfpI PF01965.24 EST48088.1 - 3.9e-31 108.1 0.2 4.5e-31 107.9 0.2 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 EST48088.1 - 0.18 11.4 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 EST48088.1 - 0.21 11.3 0.0 0.31 10.8 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I FeS PF04060.13 EST48088.1 - 1.8 8.3 6.9 2.3 8.0 0.9 2.9 2 0 0 2 2 2 0 Putative Fe-S cluster CARDB PF07705.11 EST48089.1 - 0.016 15.4 0.1 0.84 9.9 0.1 2.2 1 1 1 2 2 2 0 CARDB Ribosomal_L11 PF00298.19 EST48093.1 - 2.2e-13 50.5 0.0 3.4e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 EST48093.1 - 2.2e-11 43.4 0.1 3.6e-11 42.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Peptidase_C1 PF00112.23 EST48094.1 - 2.1e-06 28.0 0.5 8.3e-06 26.0 0.5 1.9 1 1 0 1 1 1 1 Papain family cysteine protease Peptidase_C30 PF05409.13 EST48094.1 - 0.0042 16.4 0.0 0.0061 15.9 0.0 1.2 1 0 0 1 1 1 1 Coronavirus endopeptidase C30 Inhibitor_I29 PF08246.12 EST48094.1 - 0.023 15.1 0.8 0.048 14.1 0.8 1.6 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) Pkinase PF00069.25 EST48095.1 - 0.0022 17.4 0.1 0.0045 16.4 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Ribosomal_L25p PF01386.19 EST48098.1 - 0.11 13.0 0.1 0.68 10.5 0.0 2.3 2 1 0 2 2 2 0 Ribosomal L25p family AAA_16 PF13191.6 EST48099.1 - 0.00017 22.0 0.1 0.00024 21.5 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 EST48099.1 - 0.0052 16.2 0.0 0.007 15.8 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 EST48099.1 - 0.0055 17.0 0.1 0.0064 16.8 0.1 1.4 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 EST48099.1 - 0.02 14.8 0.2 0.037 14.0 0.2 1.4 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 EST48099.1 - 0.034 14.4 0.1 0.05 13.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EST48099.1 - 0.037 14.0 0.1 0.067 13.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 EST48099.1 - 0.039 13.7 0.0 0.043 13.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EST48099.1 - 0.045 13.9 0.2 0.47 10.6 0.1 2.0 1 1 1 2 2 2 0 AAA domain Arf PF00025.21 EST48099.1 - 0.098 12.1 0.0 0.32 10.4 0.0 1.7 1 1 0 1 1 1 0 ADP-ribosylation factor family Ploopntkinase3 PF18751.1 EST48099.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA PF00004.29 EST48099.1 - 0.17 12.3 0.1 0.31 11.5 0.1 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF3105 PF11303.8 EST48099.1 - 0.18 12.0 0.0 0.24 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3105) FeoB_N PF02421.18 EST48099.1 - 0.19 11.3 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B DLIC PF05783.11 EST48099.1 - 0.19 10.5 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) ATPase PF06745.13 EST48099.1 - 0.22 10.8 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.6 EST48101.1 - 0.00011 22.6 0.1 0.00017 22.0 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 EST48101.1 - 0.0067 16.8 0.1 0.0071 16.7 0.1 1.4 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 EST48101.1 - 0.018 14.9 0.2 0.037 14.0 0.2 1.5 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 EST48101.1 - 0.035 14.4 0.1 0.051 13.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EST48101.1 - 0.038 14.0 0.1 0.067 13.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 EST48101.1 - 0.052 13.3 0.1 0.095 12.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EST48101.1 - 0.079 12.3 0.0 0.094 12.1 0.0 1.2 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EST48101.1 - 0.13 12.4 0.1 0.29 11.3 0.1 1.7 1 1 1 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 EST48101.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA PF00004.29 EST48101.1 - 0.18 12.2 0.1 0.3 11.5 0.1 1.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 EST48101.1 - 0.19 11.2 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B DLIC PF05783.11 EST48101.1 - 0.2 10.4 0.0 0.27 10.0 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) ATPase PF06745.13 EST48101.1 - 0.22 10.8 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 KaiC PAXX PF15384.6 EST48105.1 - 0.1 12.3 1.0 0.13 12.0 0.2 1.5 2 0 0 2 2 2 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 TB2_DP1_HVA22 PF03134.19 EST48106.1 - 8.5e-18 64.1 1.5 1.2e-17 63.5 1.5 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family EF-hand_8 PF13833.6 EST48107.1 - 5.2e-11 42.2 1.6 7.3e-08 32.1 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 EST48107.1 - 5e-10 39.7 3.1 1e-08 35.5 0.5 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EST48107.1 - 1.3e-09 36.9 3.9 0.0021 17.5 0.4 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EST48107.1 - 6.9e-09 34.9 1.9 0.016 15.1 0.0 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_4 PF12763.7 EST48107.1 - 0.00065 19.6 0.8 0.011 15.6 0.3 2.2 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand HEPN_AbiA_CTD PF18732.1 EST48107.1 - 0.0016 18.4 1.0 0.003 17.5 0.6 1.7 1 1 0 1 1 1 1 HEPN like, Abia C-terminal domain EF-hand_10 PF14788.6 EST48107.1 - 0.011 15.5 0.4 0.033 14.0 0.1 1.9 2 0 0 2 2 2 0 EF hand Fes1 PF08609.10 EST48108.1 - 6.4e-05 23.8 1.0 0.0001 23.1 0.3 1.8 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 Thioredoxin_11 PF18078.1 EST48108.1 - 0.1 12.7 1.9 0.85 9.7 0.2 2.4 2 1 0 2 2 2 0 Thioredoxin-like SNTX domain DUF1400 PF07176.11 EST48108.1 - 0.1 12.9 0.9 0.21 11.9 0.9 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1400) DHH PF01368.20 EST48110.1 - 2.2e-22 79.2 0.0 4.1e-22 78.3 0.0 1.5 1 1 0 1 1 1 1 DHH family DHHA2 PF02833.14 EST48110.1 - 2.1e-11 44.2 0.3 2.4e-10 40.8 0.0 2.6 3 0 0 3 3 3 1 DHHA2 domain CBS PF00571.28 EST48110.1 - 1e-10 41.9 0.0 0.00048 20.5 0.0 4.0 3 0 0 3 3 3 2 CBS domain Peptidase_A2E PF12382.8 EST48110.1 - 0.00033 20.7 0.2 0.0031 17.5 0.1 2.3 2 0 0 2 2 2 1 Retrotransposon peptidase Glucosamine_iso PF01182.20 EST48113.1 - 0.00041 20.3 0.0 0.00064 19.7 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase RNA_capsid PF03035.14 EST48113.1 - 0.25 11.4 1.6 0.37 10.8 1.6 1.3 1 1 0 1 1 1 0 Calicivirus putative RNA polymerase/capsid protein Put_Phosphatase PF06888.12 EST48114.1 - 0.00012 21.6 0.2 0.00062 19.2 0.1 2.2 2 0 0 2 2 2 1 Putative Phosphatase HTH_37 PF13744.6 EST48114.1 - 0.0045 16.9 1.5 2 8.4 0.0 3.6 3 0 0 3 3 3 2 Helix-turn-helix domain Pro_sub2 PF18513.1 EST48114.1 - 0.033 14.3 0.6 0.25 11.6 0.6 2.6 1 0 0 1 1 1 0 Prodomain subtilisin 2 DUF489 PF04356.12 EST48114.1 - 0.045 13.8 1.4 0.15 12.1 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF489) Voldacs PF03517.13 EST48114.1 - 0.065 13.4 2.2 1.3 9.1 0.2 2.9 2 1 0 2 2 2 0 Regulator of volume decrease after cellular swelling DUF5000 PF16391.5 EST48115.1 - 0.056 13.6 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function CCAP PF11105.8 EST48117.1 - 0.099 12.6 1.1 0.23 11.4 1.1 1.6 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a Metallophos PF00149.28 EST48118.1 - 3.5e-08 34.2 0.2 5.6e-08 33.5 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EST48118.1 - 2.5e-07 31.0 0.0 6.4e-07 29.7 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Flp_N PF03930.14 EST48118.1 - 0.22 11.5 1.9 25 4.9 0.0 2.9 3 0 0 3 3 3 0 Recombinase Flp protein N-terminus DUF4786 PF16027.5 EST48119.1 - 0.99 10.0 9.5 0.13 12.8 4.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4786) RAMP PF04901.13 EST48120.1 - 0.027 14.5 0.4 0.053 13.5 0.4 1.7 1 0 0 1 1 1 0 Receptor activity modifying family EF-hand_1 PF00036.32 EST48121.1 - 1.2e-10 40.1 2.2 0.00052 19.4 0.6 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 EST48121.1 - 2.1e-09 37.7 0.5 2.1e-09 37.7 0.5 1.9 1 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EST48121.1 - 1.6e-07 30.7 2.3 0.017 15.0 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 EST48121.1 - 1.2e-06 28.2 1.7 9e-05 22.2 0.2 3.4 3 1 1 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.6 EST48121.1 - 5e-05 22.6 1.0 0.012 15.0 0.3 3.0 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.7 EST48121.1 - 0.0065 16.4 0.4 0.016 15.2 0.4 1.6 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 EST48121.1 - 0.029 14.2 1.0 1.3 8.9 0.1 3.1 2 1 1 3 3 3 0 EF hand EF-hand_1 PF00036.32 EST48122.1 - 1.2e-10 40.1 2.2 0.00052 19.4 0.6 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 EST48122.1 - 2.1e-09 37.7 0.5 2.1e-09 37.7 0.5 1.9 1 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EST48122.1 - 1.6e-07 30.7 2.3 0.017 15.0 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 EST48122.1 - 1.2e-06 28.2 1.7 9e-05 22.2 0.2 3.4 3 1 1 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.6 EST48122.1 - 5e-05 22.6 1.0 0.012 15.0 0.3 3.0 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.7 EST48122.1 - 0.0065 16.4 0.4 0.016 15.2 0.4 1.6 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 EST48122.1 - 0.029 14.2 1.0 1.3 8.9 0.1 3.1 2 1 1 3 3 3 0 EF hand FWWh PF14922.6 EST48123.1 - 2.8e-08 33.8 0.6 8.3e-08 32.3 0.6 1.8 1 0 0 1 1 1 1 Protein of unknown function Ribosomal_L14 PF00238.19 EST48124.1 - 0.064 13.3 2.6 0.13 12.4 0.8 2.3 2 0 0 2 2 2 0 Ribosomal protein L14p/L23e DUF4786 PF16027.5 EST48124.1 - 4.1 7.9 12.6 0.22 12.1 4.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4786) COQ7 PF03232.13 EST48127.1 - 0.46 10.2 0.0 0.46 10.2 0.0 2.0 3 0 0 3 3 3 0 Ubiquinone biosynthesis protein COQ7 TPR_MLP1_2 PF07926.12 EST48128.1 - 0.0061 16.6 25.4 0.0061 16.6 25.4 6.7 1 1 4 7 7 7 2 TPR/MLP1/MLP2-like protein Atg14 PF10186.9 EST48128.1 - 1 8.4 111.9 0.0099 15.0 25.2 5.5 1 1 4 5 5 5 0 Vacuolar sorting 38 and autophagy-related subunit 14 LYRIC PF15686.5 EST48131.1 - 0.78 9.2 1.3 1.1 8.7 1.3 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Cnn_1N PF07989.11 EST48132.1 - 0.019 15.1 9.8 0.019 15.1 9.8 3.8 2 2 1 3 3 3 0 Centrosomin N-terminal motif 1 OrfB_IS605 PF01385.19 EST48132.1 - 2.3 8.5 13.9 1.9 8.8 6.7 2.7 1 1 2 3 3 3 0 Probable transposase OmpH PF03938.14 EST48132.1 - 3 8.2 37.7 2.2 8.6 11.1 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF4404 PF14357.6 EST48132.1 - 8.8 7.1 20.9 0.69 10.6 7.3 3.3 2 2 1 3 3 3 0 Domain of unknown function (DUF4404) Ecm29 PF13001.7 EST48133.1 - 0.0057 15.4 0.3 0.0061 15.3 0.3 1.1 1 0 0 1 1 1 1 Proteasome stabiliser DUF1664 PF07889.12 EST48133.1 - 0.06 13.4 1.1 0.07 13.2 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Phage_tail_X PF05489.12 EST48134.1 - 0.18 11.5 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 Phage Tail Protein X EGF_2 PF07974.13 EST48135.1 - 1.1e-09 38.4 145.4 0.00014 22.1 12.0 10.7 10 2 0 10 10 10 6 EGF-like domain Laminin_EGF PF00053.24 EST48135.1 - 3.8e-06 26.9 27.6 5.1e-05 23.3 10.6 8.9 4 2 4 8 8 8 2 Laminin EGF domain Ldl_recept_a PF00057.18 EST48135.1 - 0.027 14.7 1.2 0.027 14.7 1.2 9.6 8 3 1 9 9 9 0 Low-density lipoprotein receptor domain class A DnaGprimase_HBD PF16730.5 EST48136.1 - 0.035 14.2 1.1 0.047 13.8 1.1 1.2 1 0 0 1 1 1 0 DnaG-primase C-terminal, helicase-binding domain GAS PF13851.6 EST48140.1 - 0.9 8.9 24.0 0.017 14.5 13.4 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Nbl1_Borealin_N PF10444.9 EST48141.1 - 0.018 14.7 0.4 0.018 14.7 0.4 3.4 3 1 1 4 4 4 0 Nbl1 / Borealin N terminal Myb_DNA-binding PF00249.31 EST48143.1 - 1.1e-09 38.3 0.0 1.5e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST48143.1 - 0.019 15.2 0.1 0.51 10.6 0.1 2.0 1 1 1 2 2 2 0 Myb-like DNA-binding domain TIP49 PF06068.13 EST48144.1 - 1.2e-130 435.9 0.2 1.6e-130 435.4 0.2 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EST48144.1 - 4.2e-23 81.3 0.5 1.3e-22 79.7 0.5 1.9 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 EST48144.1 - 5.1e-11 43.1 3.0 9.8e-08 32.5 0.1 3.3 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EST48144.1 - 8.5e-07 29.5 0.4 2.3e-06 28.1 0.1 1.9 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EST48144.1 - 3.1e-06 27.0 0.7 0.0047 16.7 0.0 3.1 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 EST48144.1 - 1.5e-05 25.0 0.2 0.00021 21.2 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 EST48144.1 - 1.6e-05 25.2 0.0 0.029 14.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EST48144.1 - 0.00037 19.9 0.1 0.048 13.0 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DnaB_C PF03796.15 EST48144.1 - 0.00042 19.7 0.6 0.0013 18.1 0.1 2.0 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain Sigma54_activat PF00158.26 EST48144.1 - 0.0007 19.3 0.0 0.55 9.9 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Zeta_toxin PF06414.12 EST48144.1 - 0.00098 18.5 0.0 0.0022 17.3 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.6 EST48144.1 - 0.0017 18.7 0.4 1.5 9.1 0.0 2.5 2 1 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 EST48144.1 - 0.002 18.1 0.1 0.013 15.4 0.0 2.4 2 1 0 2 2 2 1 NTPase AAA_17 PF13207.6 EST48144.1 - 0.002 18.5 1.6 0.004 17.6 0.1 2.3 2 1 1 3 3 1 1 AAA domain AAA_5 PF07728.14 EST48144.1 - 0.0033 17.4 0.0 0.15 12.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EST48144.1 - 0.0044 17.3 0.0 0.012 15.8 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.6 EST48144.1 - 0.0047 17.5 0.4 0.039 14.5 0.0 2.7 3 1 1 4 4 2 1 AAA domain AAA_33 PF13671.6 EST48144.1 - 0.0087 16.2 0.0 0.034 14.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 EST48144.1 - 0.014 15.5 2.3 2.4 8.2 0.3 2.7 3 1 0 3 3 2 0 Helicase HerA, central domain AAA_25 PF13481.6 EST48144.1 - 0.023 14.3 0.0 0.049 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EST48144.1 - 0.033 13.4 0.0 0.07 12.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DNA_pol3_delta PF06144.13 EST48144.1 - 0.037 13.8 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit TsaE PF02367.17 EST48144.1 - 0.037 14.0 0.0 0.077 13.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EST48144.1 - 0.043 14.2 0.2 0.12 12.8 0.0 2.0 2 1 0 2 2 1 0 RNA helicase IstB_IS21 PF01695.17 EST48144.1 - 0.045 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein PRK PF00485.18 EST48144.1 - 0.045 13.5 0.2 0.75 9.5 0.0 2.6 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family AAA_23 PF13476.6 EST48144.1 - 0.066 13.7 0.0 0.066 13.7 0.0 2.2 2 1 0 2 2 1 0 AAA domain AAA_29 PF13555.6 EST48144.1 - 0.078 12.7 0.1 0.3 10.9 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_3 PF07726.11 EST48144.1 - 0.097 12.5 0.0 0.37 10.7 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 EST48144.1 - 0.16 11.7 1.0 0.81 9.4 0.0 2.5 3 0 0 3 3 3 0 DEAD/DEAH box helicase SMC_N PF02463.19 EST48144.1 - 0.17 11.3 0.5 3.3 7.1 0.0 2.5 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF4252 PF14060.6 EST48144.1 - 0.38 10.6 3.0 3.3 7.6 0.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4252) Myb_DNA-binding PF00249.31 EST48147.1 - 6.7e-09 35.8 0.1 2.7e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST48147.1 - 2.3e-05 24.5 0.1 0.00074 19.7 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EST48150.1 - 6.8e-09 35.8 0.1 2.7e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST48150.1 - 2.4e-05 24.5 0.1 0.00074 19.7 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain LydB PF16084.5 EST48153.1 - 5.6 6.8 10.3 41 4.0 0.4 3.3 1 1 2 3 3 3 0 LydA-holin antagonist GBS_Bsp-like PF08481.10 EST48153.1 - 8 6.7 15.2 16 5.7 0.4 3.2 1 1 2 3 3 3 0 GBS Bsp-like repeat Cyclin_N PF00134.23 EST48154.1 - 1.7e-07 31.0 0.3 2.2e-07 30.7 0.3 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain zf-CCCH_2 PF14608.6 EST48156.1 - 0.0092 16.4 15.0 0.21 12.1 3.5 2.3 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 EST48156.1 - 0.039 14.2 5.8 0.56 10.4 1.8 2.2 1 1 1 2 2 2 0 Zinc-finger containing family Ras PF00071.22 EST48157.1 - 1.9e-53 180.4 1.0 2.4e-53 180.1 1.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EST48157.1 - 5.4e-33 113.8 0.7 7.7e-33 113.3 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EST48157.1 - 1.5e-13 50.6 0.1 2e-13 50.2 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EST48157.1 - 2.4e-05 24.4 0.0 4.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EST48157.1 - 4.2e-05 23.0 0.2 6.3e-05 22.4 0.2 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EST48157.1 - 0.00035 20.2 0.1 0.0033 17.0 0.1 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EST48157.1 - 0.015 15.2 0.2 1.1 9.1 0.1 2.2 1 1 1 2 2 2 0 RsgA GTPase FeoB_N PF02421.18 EST48157.1 - 0.081 12.4 0.1 0.31 10.5 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B TFIIS_C PF01096.18 EST48158.1 - 1.4e-14 53.7 6.3 1.4e-14 53.7 6.3 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Baculo_LEF5_C PF11792.8 EST48158.1 - 0.39 10.4 8.7 0.074 12.7 3.6 2.3 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain zf-CHY PF05495.12 EST48159.1 - 4.7e-11 43.0 10.8 1.1e-10 41.8 10.8 1.6 1 1 0 1 1 1 1 CHY zinc finger Cys_rich_KTR PF14205.6 EST48159.1 - 0.0023 17.7 2.6 1.1 9.2 2.3 2.5 2 1 0 2 2 2 2 Cysteine-rich KTR Anti-TRAP PF15777.5 EST48159.1 - 0.0085 16.0 0.1 0.018 15.0 0.0 1.6 1 1 0 1 1 1 1 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EST48159.1 - 0.084 12.9 0.2 0.084 12.9 0.2 2.0 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA F-box-like PF12937.7 EST48159.1 - 0.31 11.0 1.4 0.58 10.1 1.4 1.4 1 0 0 1 1 1 0 F-box-like zinc_ribbon_4 PF13717.6 EST48159.1 - 2.3 8.2 11.8 1 9.4 4.5 3.3 2 1 0 2 2 2 0 zinc-ribbon domain RNA_POL_M_15KD PF02150.16 EST48159.1 - 3.3 7.7 9.6 12 5.8 0.0 3.1 2 1 1 3 3 3 0 RNA polymerases M/15 Kd subunit DUF3135 PF11333.8 EST48160.1 - 0.031 14.5 1.8 0.042 14.1 1.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3135) TMPIT PF07851.13 EST48160.1 - 0.041 13.1 1.0 0.044 13.0 1.0 1.0 1 0 0 1 1 1 0 TMPIT-like protein HR1 PF02185.16 EST48160.1 - 0.053 13.6 2.9 0.068 13.3 2.9 1.1 1 0 0 1 1 1 0 Hr1 repeat Toxin_32 PF08120.11 EST48161.1 - 0.44 10.4 4.2 68 3.4 0.1 3.4 3 0 0 3 3 3 0 Tamulustoxin family FPP PF05911.11 EST48162.1 - 0.00024 19.5 19.0 0.00027 19.3 19.0 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil KASH_CCD PF14662.6 EST48162.1 - 0.0078 16.1 11.7 0.0078 16.1 11.7 3.1 1 1 1 3 3 3 1 Coiled-coil region of CCDC155 or KASH kleA_kleC PF17383.2 EST48162.1 - 0.29 11.5 4.9 0.87 10.0 0.3 2.7 3 1 0 3 3 3 0 Uncharacterized KorC regulated protein A Abhydrolase_1 PF00561.20 EST48164.1 - 4.9e-06 26.4 0.3 1.8e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EST48164.1 - 0.00011 22.9 0.0 0.00034 21.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Transposase_22 PF02994.14 EST48165.1 - 0.0077 16.4 1.5 0.0077 16.4 1.5 2.9 2 2 1 3 3 3 1 L1 transposable element RBD-like domain Dapper PF15268.6 EST48165.1 - 2.8 6.7 33.8 3.1 6.6 33.8 1.0 1 0 0 1 1 1 0 Dapper EF-hand_7 PF13499.6 EST48167.1 - 4.2e-10 39.9 1.0 2.3e-09 37.6 0.1 2.4 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 EST48167.1 - 6.6e-07 28.4 1.3 0.00015 21.1 0.0 3.5 4 0 0 4 4 4 1 EF hand EF-hand_8 PF13833.6 EST48167.1 - 1.3e-06 28.2 0.0 7.7e-05 22.5 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_9 PF14658.6 EST48167.1 - 0.00014 22.1 0.0 0.0018 18.6 0.0 2.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 EST48167.1 - 0.00045 19.6 0.3 0.0035 16.8 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 EST48167.1 - 0.0019 18.0 0.8 0.35 10.9 0.1 3.3 4 0 0 4 4 4 1 EF-hand domain EF-hand_4 PF12763.7 EST48167.1 - 0.052 13.5 2.1 0.41 10.6 0.1 2.7 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 EST48168.1 - 1.8e-10 41.1 0.0 0.00032 21.1 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EST48168.1 - 7.7e-10 37.6 0.0 0.0012 18.2 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EST48168.1 - 9.5e-10 37.6 0.0 0.00062 19.5 0.0 2.7 2 1 0 2 2 2 2 EF-hand domain EF-hand_9 PF14658.6 EST48168.1 - 6.2e-07 29.6 0.0 0.0033 17.7 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EST48168.1 - 0.0038 17.1 0.1 5 7.1 0.0 3.0 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EST48168.1 - 0.005 16.3 0.0 0.3 10.6 0.0 2.7 2 0 0 2 2 2 1 EF hand Glyco_hydro_20 PF00728.22 EST48169.1 - 1.3e-29 103.7 0.7 2.4e-29 102.9 0.7 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EST48169.1 - 0.0016 19.1 0.0 0.005 17.5 0.0 1.9 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 EST48169.1 - 0.029 15.2 0.0 0.09 13.6 0.0 1.9 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 Lipocalin_4 PF13648.6 EST48169.1 - 1 10.4 5.4 4.5 8.3 0.1 3.1 3 1 0 3 3 3 0 Lipocalin-like domain P16-Arc PF04699.14 EST48170.1 - 0.12 12.9 2.4 2.3 8.7 0.4 2.2 1 1 1 2 2 2 0 ARP2/3 complex 16 kDa subunit (p16-Arc) IQ PF00612.27 EST48171.1 - 7.6e-12 43.9 8.6 0.00038 20.0 0.5 3.9 3 0 0 3 3 3 3 IQ calmodulin-binding motif DUF4136 PF13590.6 EST48171.1 - 0.28 11.8 3.5 0.43 11.2 3.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4136) DnaB PF00772.21 EST48172.1 - 0.25 11.4 4.0 5.5 7.1 0.1 3.2 3 0 0 3 3 3 0 DnaB-like helicase N terminal domain NAGidase PF07555.13 EST48173.1 - 0.022 14.1 0.1 0.97 8.7 0.0 2.1 2 0 0 2 2 2 0 beta-N-acetylglucosaminidase SHIPPO-rpt PF07004.12 EST48174.1 - 1.2e-25 89.2 62.4 0.00013 22.7 0.1 11.9 12 0 0 12 12 12 11 Sperm-tail PG-rich repeat ECR1_N PF14382.6 EST48174.1 - 0.0012 18.6 16.1 9.7 6.1 0.1 8.0 8 0 0 8 8 8 5 Exosome complex exonuclease RRP4 N-terminal region Peptidase_C1 PF00112.23 EST48175.1 - 2.4e-23 83.4 0.9 8.2e-23 81.6 0.9 1.9 1 1 0 1 1 1 1 Papain family cysteine protease Peptidase_C30 PF05409.13 EST48175.1 - 0.018 14.3 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Coronavirus endopeptidase C30 Inhibitor_I29 PF08246.12 EST48175.1 - 0.028 14.9 0.7 0.076 13.5 0.7 1.8 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) SKG6 PF08693.10 EST48177.1 - 2.5 7.6 5.6 5.2 6.6 5.6 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FtsJ PF01728.19 EST48179.1 - 0.00062 19.9 0.2 0.0038 17.4 0.1 2.4 2 1 0 2 2 2 1 FtsJ-like methyltransferase Peptidase_C58 PF03543.14 EST48179.1 - 2.5 7.8 7.2 3.9 7.1 6.2 1.8 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen DUF1160 PF06648.11 EST48180.1 - 0.057 13.4 0.2 0.21 11.6 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1160) Glucosamine_iso PF01182.20 EST48183.1 - 6.1e-15 55.7 0.0 8.7e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Pox_E8 PF03394.13 EST48183.1 - 0.073 12.6 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus E8 protein tRNA-synt_1f PF01921.18 EST48183.1 - 0.086 11.7 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (K) DUF2181 PF10223.9 EST48185.1 - 0.15 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2181) Av_adeno_fibre PF06536.11 EST48187.1 - 0.023 14.5 0.3 0.055 13.3 0.3 1.6 1 0 0 1 1 1 0 Avian adenovirus fibre, N-terminal LRR_4 PF12799.7 EST48193.1 - 3.8e-07 30.3 10.5 3.9e-05 23.9 1.5 3.9 2 2 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EST48193.1 - 0.0051 16.5 12.1 0.0098 15.6 1.7 2.9 1 1 1 2 2 2 2 Leucine rich repeat MFS_1 PF07690.16 EST48196.1 - 1.8e-31 109.4 31.8 4.6e-29 101.4 32.9 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily YwiC PF14256.6 EST48196.1 - 0.007 16.7 1.9 0.007 16.7 1.9 4.0 3 1 1 4 4 4 1 YwiC-like protein MFS_3 PF05977.13 EST48196.1 - 0.0074 14.7 12.7 0.26 9.6 6.8 2.3 2 0 0 2 2 2 2 Transmembrane secretion effector MFS_2 PF13347.6 EST48196.1 - 1.3 7.5 41.4 0.21 10.1 14.6 4.2 4 0 0 4 4 4 0 MFS/sugar transport protein PFU PF09070.11 EST48198.1 - 4.3e-09 36.6 0.0 8.8e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PQQ_3 PF13570.6 EST48198.1 - 0.62 10.6 2.3 26 5.5 0.0 3.8 5 0 0 5 5 5 0 PQQ-like domain KdpA PF03814.15 EST48201.1 - 0.023 12.9 0.1 0.026 12.7 0.1 1.0 1 0 0 1 1 1 0 Potassium-transporting ATPase A subunit B2-adapt-app_C PF09066.10 EST48201.1 - 0.038 14.1 0.1 0.05 13.7 0.1 1.1 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain Slx4 PF09494.10 EST48201.1 - 0.063 13.2 0.0 0.098 12.6 0.0 1.3 1 0 0 1 1 1 0 Slx4 endonuclease LBP_BPI_CETP PF01273.25 EST48204.1 - 0.058 13.0 5.4 0.054 13.1 3.9 1.8 2 0 0 2 2 2 0 LBP / BPI / CETP family, N-terminal domain DS PF01916.17 EST48205.1 - 1.2e-49 169.1 0.1 5.8e-48 163.6 0.1 2.0 1 1 0 1 1 1 1 Deoxyhypusine synthase DNA_pol3_delta2 PF13177.6 EST48206.1 - 6.7e-14 52.0 0.0 1.6e-09 37.8 0.0 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 EST48206.1 - 2.1e-13 50.8 0.1 8.3e-13 48.9 0.0 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EST48206.1 - 4.5e-06 27.0 0.6 0.0047 17.2 0.0 2.7 2 1 1 3 3 2 2 AAA domain Rad17 PF03215.15 EST48206.1 - 4.8e-06 26.6 0.0 8.8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 EST48206.1 - 1.4e-05 25.6 0.2 2.7e-05 24.6 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 EST48206.1 - 2.9e-05 24.1 0.0 0.00086 19.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 EST48206.1 - 7.8e-05 22.0 0.0 0.00013 21.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 EST48206.1 - 0.00035 20.8 0.0 0.00071 19.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EST48206.1 - 0.00083 18.9 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region TniB PF05621.11 EST48206.1 - 0.0009 18.7 0.0 0.0022 17.4 0.0 1.7 1 1 0 1 1 1 1 Bacterial TniB protein RuvB_N PF05496.12 EST48206.1 - 0.001 18.8 0.0 0.0062 16.3 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 EST48206.1 - 0.0017 18.4 0.0 0.0044 17.0 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EST48206.1 - 0.0021 17.8 0.1 0.012 15.4 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_23 PF13476.6 EST48206.1 - 0.0057 17.2 0.4 0.0098 16.4 0.4 1.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EST48206.1 - 0.0057 16.6 0.0 0.029 14.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) T2SSE PF00437.20 EST48206.1 - 0.0088 15.1 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein DNA_pol3_delta PF06144.13 EST48206.1 - 0.012 15.4 0.7 0.025 14.4 0.1 1.8 2 0 0 2 2 2 0 DNA polymerase III, delta subunit ATPase_2 PF01637.18 EST48206.1 - 0.017 15.0 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 EST48206.1 - 0.023 15.2 0.0 0.14 12.7 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.6 EST48206.1 - 0.024 14.4 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 EST48206.1 - 0.03 14.7 0.0 0.07 13.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 EST48206.1 - 0.033 13.9 0.1 0.18 11.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EST48206.1 - 0.034 13.9 0.0 0.049 13.4 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_assoc_2 PF16193.5 EST48206.1 - 0.047 14.0 0.1 0.1 13.0 0.1 1.6 1 0 0 1 1 1 0 AAA C-terminal domain DUF3802 PF12290.8 EST48206.1 - 0.065 13.8 0.1 0.58 10.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3802) Mg_chelatase PF01078.21 EST48206.1 - 0.097 12.0 0.0 0.69 9.3 0.0 2.1 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EST48206.1 - 0.1 12.9 0.0 0.2 11.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain ORF_12_N PF18042.1 EST48208.1 - 0.19 12.1 1.2 8.3 6.9 0.5 2.9 2 0 0 2 2 2 0 ORF 12 gene product N-terminal ABC_tran PF00005.27 EST48209.1 - 2.1e-21 76.9 0.1 4.6e-21 75.8 0.1 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EST48209.1 - 0.0028 17.5 0.4 0.096 12.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system DLIC PF05783.11 EST48209.1 - 0.14 11.0 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) RsgA_GTPase PF03193.16 EST48209.1 - 2 8.3 5.8 0.23 11.4 0.1 2.2 3 0 0 3 3 3 0 RsgA GTPase LLC1 PF14945.6 EST48212.1 - 0.016 15.8 0.0 0.017 15.7 0.0 1.1 1 0 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein MIF PF01187.18 EST48213.1 - 1.5e-14 54.3 0.1 1.8e-14 54.0 0.1 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.21 EST48213.1 - 1.2e-06 28.3 0.0 0.0025 17.7 0.0 2.2 2 0 0 2 2 2 2 Tautomerase enzyme HSP9_HSP12 PF04119.12 EST48213.1 - 0.017 15.5 0.3 0.039 14.3 0.1 1.6 2 0 0 2 2 2 0 Heat shock protein 9/12 Tautomerase_2 PF14552.6 EST48213.1 - 0.02 15.0 0.1 0.41 10.8 0.0 2.0 2 0 0 2 2 2 0 Tautomerase enzyme DUF2222 PF09984.9 EST48214.1 - 0.0013 18.6 0.4 0.0041 17.0 0.4 1.8 1 0 0 1 1 1 1 Uncharacterised signal transduction histidine kinase domain (DUF2222) Uteroglobin PF01099.17 EST48214.1 - 0.059 13.7 0.5 1.3 9.4 0.0 3.0 2 0 0 2 2 2 0 Uteroglobin family DUF1842 PF08896.10 EST48217.1 - 0.1 12.9 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1842) Snapin_Pallidin PF14712.6 EST48218.1 - 0.044 14.2 7.6 0.044 14.2 7.6 1.6 2 0 0 2 2 2 0 Snapin/Pallidin zf-CRD PF17979.1 EST48218.1 - 0.1 12.7 2.5 0.28 11.3 2.5 1.6 1 1 0 1 1 1 0 Cysteine rich domain with multizinc binding regions Peptidase_C1_2 PF03051.15 EST48218.1 - 0.13 11.0 1.3 0.14 10.9 0.8 1.3 1 1 1 2 2 2 0 Peptidase C1-like family SUIM_assoc PF16619.5 EST48218.1 - 1.8 8.7 13.9 3.4 7.8 2.5 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 LcrG PF07216.12 EST48218.1 - 3.8 7.5 9.6 1.5 8.8 2.7 2.1 2 0 0 2 2 2 0 LcrG protein Serpin PF00079.20 EST48221.1 - 9.3e-49 166.7 0.1 1.1e-48 166.5 0.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Serpin PF00079.20 EST48222.1 - 3.1e-24 86.0 0.7 1.5e-15 57.4 0.0 2.0 1 1 1 2 2 2 2 Serpin (serine protease inhibitor) Dynein_light PF01221.18 EST48224.1 - 4.4e-40 135.9 1.5 4.8e-40 135.8 1.5 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Phage_Gp111 PF07410.11 EST48224.1 - 0.035 14.6 0.4 0.037 14.5 0.4 1.1 1 0 0 1 1 1 0 Streptococcus thermophilus bacteriophage Gp111 protein Ectatomin PF06457.11 EST48224.1 - 0.17 11.8 0.3 0.3 11.0 0.3 1.3 1 0 0 1 1 1 0 Ectatomin zf-met PF12874.7 EST48225.1 - 0.00013 22.2 0.2 0.00019 21.7 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EST48225.1 - 0.0047 17.2 0.0 0.005 17.2 0.0 1.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EST48225.1 - 0.012 16.3 0.1 0.023 15.5 0.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EST48225.1 - 0.013 15.8 0.2 0.019 15.2 0.2 1.2 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 EST48225.1 - 0.04 14.4 0.1 0.066 13.7 0.1 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 EST48225.1 - 0.044 13.5 0.0 0.065 13.0 0.0 1.2 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-BED PF02892.15 EST48225.1 - 0.077 13.0 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 BED zinc finger ABC_tran PF00005.27 EST48226.1 - 4e-42 144.0 2.5 2.4e-26 92.9 0.1 3.0 3 0 0 3 3 2 2 ABC transporter ABC2_membrane_3 PF12698.7 EST48226.1 - 6.2e-14 51.9 58.2 1.8e-12 47.1 36.2 4.0 4 1 0 5 5 4 2 ABC-2 family transporter protein AAA_21 PF13304.6 EST48226.1 - 6.2e-09 36.1 0.6 0.001 19.0 0.0 3.4 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EST48226.1 - 4.3e-07 30.0 0.6 0.033 14.1 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EST48226.1 - 1.3e-06 28.1 0.7 0.022 14.5 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EST48226.1 - 9.6e-05 22.8 0.2 0.32 11.4 0.0 2.7 3 0 0 3 3 2 2 AAA ATPase domain AAA_30 PF13604.6 EST48226.1 - 0.00022 21.0 0.1 0.12 12.1 0.0 2.8 3 0 0 3 3 3 1 AAA domain TsaE PF02367.17 EST48226.1 - 0.002 18.1 0.2 0.16 12.0 0.1 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 EST48226.1 - 0.0028 17.0 1.0 0.32 10.3 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.12 EST48226.1 - 0.014 15.3 0.4 0.39 10.6 0.0 2.4 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 EST48226.1 - 0.018 15.1 1.0 5.4 7.1 0.1 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase MeaB PF03308.16 EST48226.1 - 0.019 14.0 0.3 0.52 9.3 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 EST48226.1 - 0.031 14.6 0.0 2.7 8.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EST48226.1 - 0.032 14.0 0.1 3.7 7.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain MobB PF03205.14 EST48226.1 - 0.034 14.0 0.1 2.5 8.0 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 EST48226.1 - 0.039 13.5 0.5 5 6.7 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EST48226.1 - 0.079 13.1 0.2 20 5.3 0.2 2.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EST48226.1 - 0.079 13.3 0.4 9.2 6.7 0.0 2.9 2 0 0 2 2 2 0 RNA helicase SMC_N PF02463.19 EST48226.1 - 0.12 11.8 5.5 0.4 10.1 1.1 3.6 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain DUF1359 PF07097.11 EST48226.1 - 0.14 12.4 2.5 1.2 9.4 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1359) T2SSE PF00437.20 EST48226.1 - 0.14 11.2 0.2 0.32 10.0 0.2 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 EST48226.1 - 0.32 11.5 18.9 0.052 14.1 0.8 3.9 3 1 1 4 4 3 0 AAA domain PRK PF00485.18 EST48226.1 - 0.33 10.7 2.0 16 5.2 0.2 2.8 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family DUF87 PF01935.17 EST48226.1 - 0.51 10.4 4.5 1.7 8.7 0.1 2.7 3 0 0 3 3 3 0 Helicase HerA, central domain Dynamin_N PF00350.23 EST48226.1 - 1.7 8.6 6.9 4.1 7.4 0.1 3.0 3 0 0 3 3 3 0 Dynamin family EF1_GNE PF00736.19 EST48227.1 - 2.1e-23 82.3 0.9 2.1e-23 82.3 0.9 2.2 3 0 0 3 3 3 1 EF-1 guanine nucleotide exchange domain Pox_A_type_inc PF04508.12 EST48228.1 - 0.022 14.6 1.2 0.36 10.8 0.1 3.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF4080 PF13311.6 EST48229.1 - 0.13 12.5 0.0 0.16 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4080) Pkinase PF00069.25 EST48230.1 - 1.4e-66 224.6 0.0 2.2e-66 223.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST48230.1 - 1.4e-47 162.1 0.0 2.4e-47 161.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EST48230.1 - 9.3e-08 31.2 0.9 1.4e-07 30.7 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EST48230.1 - 0.0076 15.3 2.1 0.078 12.0 0.0 2.4 2 0 0 2 2 2 1 Seadornavirus VP7 Kinase-like PF14531.6 EST48230.1 - 0.0083 15.5 0.0 0.018 14.4 0.0 1.7 1 1 0 1 1 1 1 Kinase-like ABC1 PF03109.16 EST48230.1 - 0.033 14.4 0.5 0.07 13.3 0.0 1.8 2 0 0 2 2 2 0 ABC1 family APH PF01636.23 EST48230.1 - 0.13 12.1 0.2 0.46 10.4 0.2 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family RNA_capsid PF03035.14 EST48230.1 - 0.19 11.7 0.1 0.19 11.7 0.1 1.7 2 0 0 2 2 2 0 Calicivirus putative RNA polymerase/capsid protein DUF740 PF05340.12 EST48230.1 - 1.7 7.3 4.6 2.8 6.6 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Pkinase PF00069.25 EST48231.1 - 4.3e-50 170.5 0.0 5.4e-50 170.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST48231.1 - 5.7e-19 68.4 0.1 3.4e-17 62.6 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase HD_3 PF13023.6 EST48232.1 - 3e-32 111.8 0.1 3.5e-32 111.6 0.1 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 EST48232.1 - 2e-12 47.3 1.4 1.8e-11 44.2 1.4 2.1 1 1 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 EST48232.1 - 0.00019 21.6 0.0 0.00043 20.5 0.0 1.5 1 1 0 1 1 1 1 HD domain SHS2_Rpb7-N PF03876.17 EST48232.1 - 0.072 13.5 0.1 0.24 11.8 0.0 1.8 1 1 0 1 1 1 0 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Pdase_C33_assoc PF14756.6 EST48233.1 - 0.23 11.4 0.3 0.51 10.3 0.3 1.5 1 0 0 1 1 1 0 Peptidase_C33-associated domain PHD PF00628.29 EST48234.1 - 1.8e-08 34.2 8.6 4.3e-08 32.9 8.6 1.7 1 0 0 1 1 1 1 PHD-finger zf-AN1 PF01428.16 EST48234.1 - 6.7 7.0 12.4 21 5.4 6.6 2.9 1 1 1 2 2 2 0 AN1-like Zinc finger DUF4912 PF16258.5 EST48236.1 - 0.036 14.3 0.1 0.053 13.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4912) MbtH PF03621.13 EST48236.1 - 0.14 11.7 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 MbtH-like protein DUF1899 PF08953.11 EST48236.1 - 0.25 11.2 0.9 1.3 9.0 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1899) eIF-6 PF01912.18 EST48239.1 - 4.3e-22 78.5 3.4 5.8e-22 78.0 2.9 1.4 1 1 0 1 1 1 1 eIF-6 family IFT46_B_C PF12317.8 EST48240.1 - 5.9e-37 127.5 8.5 5.9e-37 127.5 8.5 1.7 1 1 1 2 2 2 1 Intraflagellar transport complex B protein 46 C terminal eIF-6 PF01912.18 EST48241.1 - 3.3e-65 219.2 0.2 4.9e-65 218.6 0.2 1.3 1 1 0 1 1 1 1 eIF-6 family Mg296 PF09644.10 EST48244.1 - 0.039 14.1 0.0 0.57 10.3 0.0 2.2 1 1 2 3 3 3 0 Mg296 protein MbtH PF03621.13 EST48244.1 - 0.14 11.6 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 MbtH-like protein ASF1_hist_chap PF04729.13 EST48246.1 - 0.062 13.2 4.0 2.9 7.8 0.1 3.0 3 0 0 3 3 3 0 ASF1 like histone chaperone zf-HIT PF04438.16 EST48247.1 - 4.9e-06 26.3 8.9 8.9e-06 25.5 8.9 1.4 1 0 0 1 1 1 1 HIT zinc finger Dynein_attach_N PF15867.5 EST48247.1 - 0.051 13.5 0.4 0.083 12.8 0.4 1.5 1 0 0 1 1 1 0 Dynein attachment factor N-terminus VATC PF18716.1 EST48247.1 - 0.065 13.1 11.7 0.23 11.3 11.7 1.9 1 1 0 1 1 1 0 Vms1-associating treble clef domain CEBP_ZZ PF16366.5 EST48247.1 - 0.097 12.9 10.5 0.17 12.2 10.5 1.4 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Pkinase PF00069.25 EST48249.1 - 5.9e-05 22.6 4.3 0.067 12.5 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EST48249.1 - 0.0011 18.3 0.0 0.025 13.9 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Choline_kinase PF01633.20 EST48249.1 - 0.016 14.8 0.6 0.068 12.8 0.4 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase AAA_6 PF12774.7 EST48250.1 - 8.2e-127 422.7 1.0 1.2e-124 415.5 1.0 3.1 1 1 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EST48250.1 - 2.8e-98 329.6 17.3 2.8e-98 329.6 17.3 3.3 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 EST48250.1 - 4.9e-79 265.7 0.4 4.9e-79 265.7 0.4 2.4 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 EST48250.1 - 6e-48 163.4 2.5 1.7e-43 148.8 0.0 4.3 3 1 0 3 3 3 2 P-loop containing dynein motor region D4 AAA_7 PF12775.7 EST48250.1 - 5.8e-44 149.8 7.1 3e-42 144.2 0.0 4.6 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_9 PF12781.7 EST48250.1 - 8.2e-40 136.3 2.6 8.2e-40 136.3 2.6 5.4 7 0 0 7 7 5 1 ATP-binding dynein motor region Dynein_heavy PF03028.15 EST48250.1 - 4.9e-32 110.5 0.5 1.1e-30 106.1 0.0 3.8 4 0 0 4 4 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 EST48250.1 - 2e-29 102.7 12.5 5.3e-29 101.3 12.5 1.7 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 EST48250.1 - 2.2e-22 79.6 0.1 1.3e-21 77.1 0.1 2.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_AAA_lid PF17852.1 EST48250.1 - 3e-13 50.0 0.7 1.9e-12 47.4 0.0 3.0 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 EST48250.1 - 1.9e-12 47.8 2.2 4e-06 27.3 0.0 5.8 6 0 0 6 6 4 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EST48250.1 - 2.3e-12 47.1 0.0 0.0028 17.7 0.0 6.4 7 0 0 7 7 6 2 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 EST48250.1 - 1.1e-11 44.8 0.1 6.7e-11 42.3 0.1 2.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 EST48250.1 - 1.5e-07 31.7 0.2 0.0037 17.5 0.0 5.1 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.6 EST48250.1 - 8e-07 29.6 6.6 0.013 15.9 0.0 6.2 6 0 0 6 6 6 1 AAA ATPase domain AAA_18 PF13238.6 EST48250.1 - 7.2e-06 26.6 4.0 0.18 12.4 0.1 5.5 5 0 0 5 5 5 1 AAA domain AAA_33 PF13671.6 EST48250.1 - 0.00042 20.5 1.0 0.96 9.6 0.0 4.3 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.22 EST48250.1 - 0.0041 17.5 1.6 21 5.5 0.0 4.5 4 0 0 4 4 3 0 RNA helicase AAA_24 PF13479.6 EST48250.1 - 0.036 13.8 0.6 4.4 7.0 0.0 4.0 3 0 0 3 3 3 0 AAA domain Cytidylate_kin PF02224.18 EST48250.1 - 0.036 13.8 0.4 10 5.7 0.0 3.6 3 0 0 3 3 3 0 Cytidylate kinase DUF3605 PF12239.8 EST48250.1 - 0.06 13.7 3.5 0.13 12.6 0.4 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3605) Sigma54_activat PF00158.26 EST48250.1 - 0.099 12.3 0.0 0.32 10.7 0.0 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 EST48250.1 - 0.1 12.7 0.0 0.1 12.7 0.0 3.1 4 0 0 4 4 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 EST48250.1 - 0.2 12.2 0.0 0.2 12.2 0.0 4.6 5 0 0 5 5 2 0 ABC transporter SRPRB PF09439.10 EST48250.1 - 0.31 10.5 5.8 0.12 11.7 0.0 3.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF745 PF05335.13 EST48250.1 - 0.49 10.1 25.7 0.088 12.5 3.6 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF745) zf-CHY PF05495.12 EST48251.1 - 2e-09 37.8 25.2 2e-09 37.8 25.2 3.9 2 1 1 3 3 3 1 CHY zinc finger zf-RING_5 PF14634.6 EST48251.1 - 2.5e-06 27.3 4.9 2.5e-06 27.3 4.9 6.1 3 1 2 5 5 5 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EST48251.1 - 0.00015 21.5 4.3 0.00015 21.5 4.3 5.6 3 1 2 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-CHY PF05495.12 EST48253.1 - 8.5e-10 39.0 16.4 8.5e-10 39.0 16.4 4.4 1 1 2 3 3 3 1 CHY zinc finger zf-RING_5 PF14634.6 EST48253.1 - 3e-06 27.1 3.7 3e-06 27.1 3.7 6.8 5 3 0 5 5 5 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EST48253.1 - 0.0098 15.7 4.5 0.0098 15.7 4.5 6.3 2 1 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) VSP PF03302.13 EST48254.1 - 0.00014 20.8 95.1 0.022 13.6 48.4 4.4 1 1 3 4 4 4 2 Giardia variant-specific surface protein BHD_1 PF10403.9 EST48255.1 - 0.11 12.3 0.0 2.5 8.0 0.0 2.5 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 1 Fumble PF03630.14 EST48256.1 - 4.7e-51 173.9 0.4 3e-36 125.3 0.0 2.4 1 1 1 2 2 2 2 Fumble BcrAD_BadFG PF01869.20 EST48256.1 - 0.045 13.2 0.1 0.18 11.3 0.1 2.0 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family GYF PF02213.16 EST48257.1 - 5.7e-10 38.7 0.0 1e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 GYF domain Syja_N PF02383.18 EST48259.1 - 0.00044 19.7 0.0 0.001 18.4 0.0 1.7 1 0 0 1 1 1 1 SacI homology domain DNA_primase_S PF01896.19 EST48260.1 - 1.9e-29 103.0 1.2 3.3e-29 102.2 1.2 1.4 1 0 0 1 1 1 1 DNA primase small subunit DUF2644 PF10841.8 EST48261.1 - 0.25 11.6 1.3 2.6 8.4 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2644) Cu-oxidase_2 PF07731.14 EST48267.1 - 0.087 12.6 0.5 0.47 10.2 0.2 2.0 2 0 0 2 2 2 0 Multicopper oxidase zf-UBP PF02148.19 EST48267.1 - 0.1 12.9 0.6 0.35 11.2 0.6 1.9 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein DUF3994 PF13159.6 EST48268.1 - 0.021 15.3 1.2 0.05 14.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3994) DUF1120 PF06551.12 EST48268.1 - 0.089 13.0 0.1 2.6 8.3 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1120) DUF4370 PF14290.6 EST48268.1 - 0.096 12.5 0.2 0.18 11.7 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4370) CBM_17_28 PF03424.14 EST48268.1 - 0.22 11.2 3.7 0.38 10.4 3.7 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain (family 17/28) PIP5K PF01504.18 EST48271.1 - 1.4e-45 155.7 6.6 4.5e-43 147.4 6.6 2.1 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase tRNA-synt_1g PF09334.11 EST48272.1 - 6.4e-95 318.2 4.8 1.1e-93 314.1 4.8 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EST48272.1 - 3.8e-28 98.1 7.7 4.6e-15 54.9 2.0 4.0 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 EST48272.1 - 1.9e-10 40.6 0.7 4.6e-05 22.9 0.9 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain RL10P_insert PF17777.1 EST48272.1 - 0.11 12.5 0.1 0.41 10.7 0.1 2.0 1 1 0 1 1 1 0 Insertion domain in 60S ribosomal protein L10P PseudoU_synth_2 PF00849.22 EST48273.1 - 4.2e-28 98.4 0.1 7.1e-28 97.7 0.1 1.4 1 1 0 1 1 1 1 RNA pseudouridylate synthase tRNA-synt_1b PF00579.25 EST48274.1 - 1e-44 153.0 0.0 1.2e-44 152.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) CENP-B_N PF04218.13 EST48274.1 - 0.098 12.3 1.1 7.6 6.3 0.0 3.2 4 0 0 4 4 4 0 CENP-B N-terminal DNA-binding domain ORF6N PF10543.9 EST48275.1 - 0.044 14.0 2.4 0.12 12.6 2.5 1.8 1 1 0 1 1 1 0 ORF6N domain SARAF PF06682.12 EST48276.1 - 3e-26 92.9 0.2 3e-26 92.9 0.2 1.5 2 0 0 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis CW_binding_1 PF01473.20 EST48276.1 - 0.0038 17.5 2.4 0.89 10.0 0.3 3.0 2 0 0 2 2 2 2 Putative cell wall binding repeat MAR_sialic_bdg PF10564.9 EST48276.1 - 0.012 15.6 1.4 0.012 15.6 1.4 2.0 2 0 0 2 2 2 0 Sialic-acid binding micronemal adhesive repeat Tipalpha PF16753.5 EST48277.1 - 0.0083 16.0 0.4 0.0083 16.0 0.4 2.0 2 0 0 2 2 2 1 TNF-alpha-Inducing protein of Helicobacter DRE2_N PF16803.5 EST48277.1 - 0.02 15.1 0.2 0.035 14.4 0.2 1.4 1 0 0 1 1 1 0 Fe-S cluster assembly protein DRE2 N-terminus DUF4382 PF14321.6 EST48277.1 - 0.047 13.9 0.3 0.063 13.5 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4382) Insulin_TMD PF17870.1 EST48280.1 - 0.0026 17.8 0.2 0.0087 16.1 0.2 1.9 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment CytochromB561_N PF09786.9 EST48280.1 - 0.0085 15.1 0.3 0.01 14.9 0.3 1.1 1 0 0 1 1 1 1 Cytochrome B561, N terminal DUF3094 PF11293.8 EST48280.1 - 0.061 13.1 0.2 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) Lipase_GDSL_lke PF16255.5 EST48280.1 - 0.086 12.2 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase DUF4307 PF14155.6 EST48280.1 - 0.15 11.9 1.5 1.2 9.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) FeoB_associated PF12669.7 EST48280.1 - 0.56 10.7 1.7 1.1 9.7 1.7 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein LRR_6 PF13516.6 EST48281.1 - 0.0029 17.5 0.8 42 4.6 0.0 5.2 5 0 0 5 5 5 2 Leucine Rich repeat SWIRM PF04433.17 EST48282.1 - 3e-06 27.5 0.0 3.7e-05 24.0 0.0 2.8 3 0 0 3 3 3 1 SWIRM domain RRP36 PF06102.12 EST48282.1 - 0.064 13.2 0.3 0.13 12.2 0.3 1.4 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 VSP PF03302.13 EST48284.1 - 1.2e-10 40.8 268.2 0.0082 15.0 38.9 9.7 1 1 8 9 9 9 8 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST48284.1 - 0.0039 17.3 19.2 0.0039 17.3 19.2 10.4 1 1 8 9 9 9 2 Furin-like repeat, cysteine-rich VSP PF03302.13 EST48285.1 - 1.6e-10 40.4 67.8 2.4e-09 36.6 36.3 5.3 1 1 4 5 5 5 3 Giardia variant-specific surface protein VSP PF03302.13 EST48286.1 - 4.4e-08 32.4 69.3 2e-07 30.2 36.5 5.5 1 1 4 5 5 5 4 Giardia variant-specific surface protein VSP PF03302.13 EST48287.1 - 3.6e-08 32.7 11.1 6.5e-07 28.5 11.1 2.0 1 1 0 1 1 1 1 Giardia variant-specific surface protein DUF4366 PF14283.6 EST48287.1 - 0.045 13.8 0.0 0.045 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Laminin_EGF PF00053.24 EST48287.1 - 0.071 13.3 4.2 0.23 11.6 4.2 1.8 1 1 0 1 1 1 0 Laminin EGF domain CD99L2 PF12301.8 EST48287.1 - 0.13 12.6 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 CD99 antigen like protein 2 EGF_MSP1_1 PF12946.7 EST48287.1 - 0.2 11.8 6.7 3.2 7.9 0.1 2.8 2 1 0 2 2 2 0 MSP1 EGF domain 1 DUF4748 PF15932.5 EST48287.1 - 0.34 10.7 1.8 0.68 9.7 1.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) CYYR1 PF10873.8 EST48287.1 - 1.1 9.7 6.1 0.79 10.2 4.9 1.4 1 1 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 VSP PF03302.13 EST48288.1 - 4.8e-06 25.7 24.0 4.8e-06 25.7 24.0 3.1 1 1 2 3 3 3 2 Giardia variant-specific surface protein DUF4366 PF14283.6 EST48288.1 - 0.036 14.1 3.9 0.92 9.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) VSP PF03302.13 EST48289.1 - 1.6e-10 40.4 67.8 2.4e-09 36.6 36.3 5.3 1 1 4 5 5 5 3 Giardia variant-specific surface protein Pox_A_type_inc PF04508.12 EST48298.1 - 0.053 13.4 0.2 0.44 10.5 0.0 2.8 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Myb_DNA-binding PF00249.31 EST48299.1 - 4.3e-06 26.8 0.0 1.1e-05 25.5 0.0 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EST48299.1 - 0.00015 21.9 0.6 0.00015 21.9 0.6 1.6 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_6 PF13921.6 EST48299.1 - 0.0012 19.1 0.1 0.0015 18.7 0.1 1.5 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST48299.1 - 0.028 14.3 0.4 0.041 13.8 0.4 1.4 1 1 0 1 1 1 0 Myb DNA-binding like DUF1107 PF06526.12 EST48303.1 - 0.009 15.9 0.1 0.032 14.1 0.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1107) MatE PF01554.18 EST48305.1 - 1.8e-28 99.2 36.0 1.3e-17 63.9 9.7 2.5 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 EST48305.1 - 0.0022 18.1 10.4 0.0022 18.1 10.4 4.7 4 1 1 5 5 5 2 Polysaccharide biosynthesis C-terminal domain DUF2024 PF09630.10 EST48306.1 - 0.061 13.2 0.4 0.12 12.3 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2024) HAND PF09110.11 EST48306.1 - 0.076 13.8 1.0 5.5 7.8 0.1 2.4 2 0 0 2 2 2 0 HAND FAD_binding_1 PF00667.20 EST48307.1 - 0.0026 17.4 0.2 0.0051 16.4 0.2 1.7 1 1 0 1 1 1 1 FAD binding domain LRR_4 PF12799.7 EST48309.1 - 0.0022 18.3 12.4 0.14 12.6 2.0 3.6 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EST48309.1 - 0.0058 16.4 8.9 1 9.2 0.7 3.7 2 1 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 EST48309.1 - 5.2 8.0 17.1 80 4.4 1.3 5.5 4 2 0 4 4 4 0 Leucine Rich Repeat DBR1 PF05011.13 EST48314.1 - 0.014 15.8 1.7 2.1 8.7 0.2 2.2 2 0 0 2 2 2 0 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 EST48315.1 - 3.7e-34 119.0 0.0 5.1e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Exonuc_VII_L PF02601.15 EST48316.1 - 0.28 10.7 17.8 1.4 8.4 3.8 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit OmpH PF03938.14 EST48316.1 - 0.66 10.3 51.8 0.1 12.9 12.2 3.3 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) PIN_2 PF10130.9 EST48316.1 - 1.3 9.3 4.7 2.9 8.1 0.2 2.7 2 1 0 2 2 2 0 PIN domain UFD1 PF03152.14 EST48317.1 - 0.0014 18.1 2.3 0.0016 18.0 0.5 2.0 2 0 0 2 2 2 1 Ubiquitin fusion degradation protein UFD1 I_LWEQ PF01608.17 EST48317.1 - 0.08 13.2 5.5 0.057 13.7 3.6 1.7 1 1 0 1 1 1 0 I/LWEQ domain DUF4407 PF14362.6 EST48317.1 - 0.088 12.1 7.1 0.14 11.5 7.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tropomyosin_1 PF12718.7 EST48317.1 - 0.42 10.8 11.1 0.85 9.8 11.1 1.5 1 0 0 1 1 1 0 Tropomyosin like BORG_CEP PF14957.6 EST48317.1 - 0.74 11.0 5.9 0.69 11.1 4.3 1.8 2 0 0 2 2 2 0 Cdc42 effector Uso1_p115_C PF04871.13 EST48317.1 - 1.3 9.4 14.3 0.15 12.4 6.9 2.4 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Asp-B-Hydro_N PF05279.11 EST48317.1 - 1.5 8.8 5.1 2.3 8.3 5.1 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PAP2 PF01569.21 EST48319.1 - 5.9e-17 61.7 4.4 5.9e-17 61.7 4.4 2.1 2 1 0 2 2 2 1 PAP2 superfamily DUF1772 PF08592.11 EST48319.1 - 3.3 8.0 16.0 13 6.1 8.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) MelC1 PF06236.11 EST48320.1 - 0.13 12.3 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 BPL_LplA_LipB PF03099.19 EST48321.1 - 0.00074 19.4 0.1 0.062 13.2 0.1 2.2 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Ribosomal_L18A PF01775.17 EST48322.1 - 2.1e-20 73.0 0.0 2.7e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A 7TMR-HDED PF07697.11 EST48323.1 - 5.1 7.1 11.2 8.4 6.4 11.2 1.3 1 0 0 1 1 1 0 7TM-HD extracellular ATP_synt_H PF05493.13 EST48324.1 - 1.8e-13 50.7 9.4 2e-13 50.6 9.4 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF4064 PF13273.6 EST48324.1 - 0.012 15.9 1.4 0.018 15.3 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) ABC2_membrane_5 PF13346.6 EST48324.1 - 0.014 14.9 4.6 0.015 14.8 4.6 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein VIT1 PF01988.19 EST48324.1 - 0.1 12.5 2.7 0.098 12.5 2.7 1.0 1 0 0 1 1 1 0 VIT family DUF5381 PF17353.2 EST48324.1 - 0.68 9.7 3.7 0.74 9.6 3.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5381) DUF2207 PF09972.9 EST48324.1 - 1.7 7.3 4.2 1.8 7.2 4.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4131 PF13567.6 EST48324.1 - 2.6 7.7 4.8 2.9 7.5 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) PP2C PF00481.21 EST48325.1 - 7.5e-39 133.9 0.3 1.2e-38 133.3 0.3 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EST48325.1 - 1e-08 35.1 0.0 2.5e-08 33.8 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C Ribosomal_L18A PF01775.17 EST48326.1 - 1.6e-33 115.4 1.4 2e-33 115.1 1.4 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A DUF3592 PF12158.8 EST48326.1 - 0.019 15.0 0.7 0.03 14.4 0.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3592) BPL_LplA_LipB PF03099.19 EST48327.1 - 0.00075 19.4 0.1 0.062 13.2 0.1 2.2 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Arm PF00514.23 EST48330.1 - 4.1e-06 26.6 10.2 0.022 14.8 0.0 6.8 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat RasGEF_N_2 PF14663.6 EST48330.1 - 0.03 14.7 0.4 2.7 8.4 0.0 3.2 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain MMS19_N PF14500.6 EST48330.1 - 1.9 8.0 15.7 0.39 10.3 2.6 3.3 2 1 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II Gastrin PF00918.17 EST48330.1 - 6.1 7.8 5.2 25 5.8 0.8 3.0 3 0 0 3 3 3 0 Gastrin/cholecystokinin family TPR_17 PF13431.6 EST48331.1 - 1.8e-06 27.9 3.8 0.11 12.9 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EST48331.1 - 4.9e-06 27.0 10.3 0.0042 17.6 1.8 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EST48331.1 - 6.7e-06 25.7 3.3 0.025 14.3 0.0 4.0 4 0 0 4 4 4 2 TPR repeat TPR_2 PF07719.17 EST48331.1 - 0.00017 21.5 2.4 0.091 12.9 0.1 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EST48331.1 - 0.0067 16.2 0.3 0.0067 16.2 0.3 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EST48331.1 - 0.0077 16.5 1.9 0.06 13.6 0.4 2.9 1 1 0 2 2 2 1 Tetratricopeptide repeat PPR_long PF17177.4 EST48331.1 - 0.012 15.0 0.3 0.022 14.1 0.3 1.4 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP TPR_8 PF13181.6 EST48331.1 - 0.064 13.5 2.9 3.5 8.1 0.4 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 EST48331.1 - 0.074 13.4 4.9 0.42 11.0 0.3 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EST48331.1 - 0.52 11.1 7.9 0.46 11.2 0.4 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 EST48331.1 - 0.97 10.1 11.8 18 6.1 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Dzip-like_N PF13815.6 EST48332.1 - 0.0068 16.4 0.4 0.0079 16.2 0.4 1.1 1 0 0 1 1 1 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal Ribosomal_L18A PF01775.17 EST48333.1 - 1.6e-33 115.4 1.4 2e-33 115.1 1.4 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A DUF3592 PF12158.8 EST48333.1 - 0.019 15.0 0.7 0.03 14.4 0.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3592) BPL_LplA_LipB PF03099.19 EST48334.1 - 0.00074 19.4 0.1 0.062 13.2 0.1 2.2 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family PAP2 PF01569.21 EST48335.1 - 8.1e-17 61.3 2.3 8.1e-17 61.3 2.3 1.8 2 0 0 2 2 2 1 PAP2 superfamily Herpes_LMP1 PF05297.11 EST48335.1 - 1.2 8.3 3.8 2.1 7.5 0.5 2.0 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) DUF1772 PF08592.11 EST48335.1 - 5.3 7.4 11.0 8.3 6.7 4.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) DUF1126 PF06565.12 EST48336.1 - 0.037 13.8 0.1 0.047 13.5 0.1 1.2 1 0 0 1 1 1 0 DUF1126 PH-like domain SNAP PF14938.6 EST48337.1 - 7.6e-18 64.9 16.8 5.6e-16 58.8 16.8 2.0 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP DUF2753 PF10952.8 EST48337.1 - 0.00082 19.5 1.8 0.052 13.7 0.3 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF2753) TPR_12 PF13424.6 EST48337.1 - 0.00095 19.4 1.9 1 9.7 0.1 3.3 2 2 1 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EST48337.1 - 0.014 15.6 5.5 5.1 7.4 0.6 3.6 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EST48337.1 - 0.041 14.7 1.9 14 6.8 0.1 3.8 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.6 EST48337.1 - 0.053 12.7 0.1 0.19 10.9 0.0 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EST48337.1 - 0.063 13.9 3.1 20 6.1 0.1 4.1 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EST48337.1 - 0.28 11.7 3.8 36 5.0 0.1 4.2 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 EST48337.1 - 0.6 10.5 6.1 13 6.3 0.5 4.2 2 2 3 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 EST48337.1 - 1.3 9.8 4.1 18 6.1 0.5 3.3 2 1 3 5 5 5 0 Tetratricopeptide repeat Brix PF04427.18 EST48338.1 - 1.1e-16 61.5 0.7 1.1e-16 61.5 0.7 1.4 2 0 0 2 2 2 1 Brix domain NOA36 PF06524.12 EST48338.1 - 0.054 12.8 1.5 0.074 12.4 1.5 1.1 1 0 0 1 1 1 0 NOA36 protein Leu_zip PF15294.6 EST48339.1 - 5.7e-10 39.2 12.8 2.3e-06 27.4 5.2 2.1 1 1 1 2 2 2 2 Leucine zipper PKcGMP_CC PF16808.5 EST48339.1 - 2.3e-06 27.3 7.7 0.0011 18.7 0.6 3.1 3 0 0 3 3 3 2 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF3708 PF12501.8 EST48339.1 - 0.12 12.1 1.7 0.23 11.2 0.2 1.9 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter TMF_TATA_bd PF12325.8 EST48339.1 - 0.56 10.5 13.4 1.1 9.5 5.6 3.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding LMBR1 PF04791.16 EST48339.1 - 2 7.2 4.9 2.2 7.1 4.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Pox_A_type_inc PF04508.12 EST48339.1 - 3 7.9 5.8 94 3.1 0.0 3.9 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat DUF2203 PF09969.9 EST48339.1 - 5.4 7.8 7.8 4e+02 1.7 7.8 2.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Med9 PF07544.13 EST48342.1 - 0.058 13.5 0.0 0.079 13.1 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 PP2C PF00481.21 EST48344.1 - 5.2e-20 72.2 0.0 7.4e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EST48344.1 - 1.2e-08 34.9 0.0 2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Myb_DNA-binding PF00249.31 EST48345.1 - 1.9e-09 37.6 0.2 2.7e-09 37.1 0.2 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST48345.1 - 1.3e-07 31.7 0.5 1.6e-07 31.4 0.5 1.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST48345.1 - 5.2e-06 26.3 0.2 5.9e-06 26.1 0.2 1.2 1 0 0 1 1 1 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EST48345.1 - 0.0011 19.1 0.6 0.0014 18.8 0.6 1.4 1 1 0 1 1 1 1 SANT/Myb-like domain of DAMP1 CcmD PF04995.14 EST48348.1 - 0.15 12.1 0.1 0.29 11.3 0.1 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DHHC PF01529.20 EST48349.1 - 5.1e-20 71.9 11.0 5.1e-20 71.9 11.0 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF4282 PF14110.6 EST48349.1 - 4.6 8.1 0.0 4.6 8.1 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4282) Bac_export_2 PF01312.19 EST48367.1 - 1.7 7.8 8.0 2 7.6 8.0 1.1 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Fig1 PF12351.8 EST48373.1 - 0.037 13.9 0.0 0.044 13.7 0.0 1.1 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 SF3A3 PF16837.5 EST48373.1 - 0.051 14.1 0.9 0.14 12.7 0.4 1.9 1 1 1 2 2 2 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 zf-TFIIIC PF12660.7 EST48375.1 - 0.017 15.1 0.6 0.017 15.1 0.6 1.9 1 1 0 2 2 2 0 Putative zinc-finger of transcription factor IIIC complex DUF4249 PF14054.6 EST48378.1 - 0.012 15.3 0.1 0.29 10.7 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4249) LRR_4 PF12799.7 EST48378.1 - 2.4 8.7 13.1 4.9 7.7 2.3 5.6 5 2 0 5 5 5 0 Leucine Rich repeats (2 copies) Med9 PF07544.13 EST48381.1 - 0.058 13.5 0.0 0.079 13.1 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 UL41A PF17591.2 EST48382.1 - 2 8.6 8.6 0.14 12.2 0.3 2.8 3 0 0 3 3 3 0 Herpesvirus UL41A PP2C PF00481.21 EST48383.1 - 5.5e-20 72.1 0.0 8e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EST48383.1 - 1.1e-08 35.0 0.0 1.8e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Myb_DNA-binding PF00249.31 EST48384.1 - 1.9e-09 37.6 0.2 2.7e-09 37.1 0.2 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST48384.1 - 1.3e-07 31.7 0.5 1.6e-07 31.4 0.5 1.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST48384.1 - 5.2e-06 26.3 0.2 5.9e-06 26.1 0.2 1.2 1 0 0 1 1 1 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EST48384.1 - 0.0011 19.1 0.6 0.0014 18.8 0.6 1.4 1 1 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-binding PF00249.31 EST48385.1 - 1.9e-09 37.6 0.2 2.7e-09 37.1 0.2 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST48385.1 - 1.3e-07 31.7 0.5 1.6e-07 31.4 0.5 1.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST48385.1 - 5.2e-06 26.3 0.2 5.9e-06 26.1 0.2 1.2 1 0 0 1 1 1 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EST48385.1 - 0.0011 19.1 0.6 0.0014 18.8 0.6 1.4 1 1 0 1 1 1 1 SANT/Myb-like domain of DAMP1 PP2C PF00481.21 EST48386.1 - 7.9e-21 74.8 0.1 2.6e-19 69.8 0.0 2.2 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 EST48386.1 - 2.7e-08 33.7 0.0 6.7e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C PIG-P PF08510.12 EST48387.1 - 0.0047 16.8 1.5 0.013 15.4 0.2 2.2 1 1 1 2 2 2 1 PIG-P UL41A PF17591.2 EST48387.1 - 0.02 14.9 0.2 0.063 13.4 0.2 1.8 1 0 0 1 1 1 0 Herpesvirus UL41A Alfin PF12165.8 EST48387.1 - 0.15 11.7 0.0 0.47 10.1 0.0 1.8 1 1 1 2 2 2 0 Alfin Na_H_antiport_1 PF06965.12 EST48387.1 - 0.18 10.6 5.0 0.35 9.6 5.1 1.5 1 1 0 1 1 1 0 Na+/H+ antiporter 1 Med9 PF07544.13 EST48388.1 - 0.058 13.5 0.0 0.079 13.1 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF3420 PF11900.8 EST48390.1 - 0.16 12.1 0.5 0.72 10.0 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3420) PCRF PF03462.18 EST48390.1 - 0.28 11.0 1.2 0.58 10.0 1.2 1.5 1 0 0 1 1 1 0 PCRF domain NAD_binding_8 PF13450.6 EST48391.1 - 0.28 11.4 1.9 0.53 10.6 1.9 1.4 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Sushi PF00084.20 EST48391.1 - 0.56 10.8 4.2 0.56 10.8 0.7 2.7 1 1 0 2 2 2 0 Sushi repeat (SCR repeat) SVWC PF15430.6 EST48391.1 - 0.62 10.4 9.3 9 6.7 1.1 3.4 2 1 1 3 3 3 0 Single domain von Willebrand factor type C Bac_small_YrzI PF09501.10 EST48392.1 - 0.039 14.1 0.1 0.05 13.8 0.1 1.1 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) DUF5074 PF16819.5 EST48393.1 - 0.0055 16.7 0.0 0.028 14.4 0.0 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5074) Bac_small_YrzI PF09501.10 EST48394.1 - 0.039 14.1 0.1 0.05 13.8 0.1 1.1 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) NAD_binding_8 PF13450.6 EST48395.1 - 0.28 11.4 1.9 0.53 10.6 1.9 1.4 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Sushi PF00084.20 EST48395.1 - 0.56 10.8 4.2 0.56 10.8 0.7 2.7 1 1 0 2 2 2 0 Sushi repeat (SCR repeat) SVWC PF15430.6 EST48395.1 - 0.62 10.4 9.3 9 6.7 1.1 3.4 2 1 1 3 3 3 0 Single domain von Willebrand factor type C VSP PF03302.13 EST48397.1 - 3.8e-06 26.0 85.6 0.0065 15.4 46.7 2.4 1 1 1 2 2 2 2 Giardia variant-specific surface protein Podoplanin PF05808.11 EST48397.1 - 1.5 8.9 9.2 2.6 8.1 9.2 1.5 1 1 0 1 1 1 0 Podoplanin WD40_like PF17005.5 EST48399.1 - 0.0018 17.7 5.6 0.0032 16.9 1.2 2.2 2 0 0 2 2 2 2 WD40-like domain SOGA PF11365.8 EST48402.1 - 0.042 15.0 1.9 0.042 15.0 1.9 2.3 2 0 0 2 2 2 0 Protein SOGA JIP_LZII PF16471.5 EST48402.1 - 0.044 13.9 8.6 5.3 7.3 1.1 3.4 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II GyrB_insert PF18053.1 EST48402.1 - 0.17 11.8 6.3 0.59 10.0 2.1 2.3 1 1 0 2 2 2 0 DNA gyrase B subunit insert domain HALZ PF02183.18 EST48402.1 - 0.53 10.6 12.5 7.4 6.9 0.1 3.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper XhlA PF10779.9 EST48402.1 - 1.4 9.1 6.9 0.64 10.3 3.4 2.2 2 1 0 2 2 2 0 Haemolysin XhlA Csm1_N PF18504.1 EST48402.1 - 2.8 8.4 22.4 0.82 10.0 7.1 3.2 2 1 1 3 3 3 0 Csm1 N-terminal domain DUF2203 PF09969.9 EST48402.1 - 3.9 8.2 11.7 2.2e+03 -0.6 11.7 2.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) CHDCT2 PF08074.11 EST48402.1 - 6.6 6.9 11.9 0.43 10.7 2.1 2.1 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain Lipoprotein_17 PF04200.12 EST48402.1 - 7.9 6.9 16.6 2e+03 -0.8 15.9 2.6 1 1 0 1 1 1 0 Lipoprotein associated domain Spec3 PF15795.5 EST48403.1 - 1.1 9.8 20.5 19 5.9 20.5 2.0 1 1 0 1 1 1 0 Ectodermal ciliogenesis protein Glyco_hydro_125 PF06824.11 EST48405.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Metal-independent alpha-mannosidase (GH125) CDP-OH_P_transf PF01066.21 EST48407.1 - 8.6e-08 32.8 0.1 8.6e-08 32.8 0.1 3.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF2628 PF10947.8 EST48407.1 - 0.56 10.6 4.2 9 6.7 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) Proteasome PF00227.26 EST48408.1 - 3.5e-31 108.2 0.0 4e-31 108.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit IpaB_EvcA PF03278.13 EST48408.1 - 0.0099 15.6 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 1 IpaB/EvcA family 5_3_exonuc PF01367.20 EST48411.1 - 0.002 18.7 0.0 0.0033 18.0 0.0 1.3 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 EST48411.1 - 0.016 15.8 0.0 0.032 14.8 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix domain IMS_HHH PF11798.8 EST48411.1 - 0.018 15.3 0.0 0.038 14.3 0.0 1.5 1 0 0 1 1 1 0 IMS family HHH motif Vps53_N PF04100.12 EST48413.1 - 0.019 14.0 0.3 0.019 14.0 0.3 2.0 1 1 1 2 2 2 0 Vps53-like, N-terminal DUF2543 PF10820.8 EST48413.1 - 0.041 14.1 0.6 0.098 12.8 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2543) DUF480 PF04337.12 EST48413.1 - 0.069 13.2 3.1 0.11 12.5 3.0 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF480 THDPS_N_2 PF14805.6 EST48413.1 - 0.15 12.3 0.6 5.6 7.3 0.0 2.3 2 1 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Dynactin_p22 PF07426.11 EST48413.1 - 0.18 11.6 10.2 0.52 10.2 10.2 1.6 1 1 0 1 1 1 0 Dynactin subunit p22 Exonuc_VII_L PF02601.15 EST48413.1 - 0.2 11.2 6.7 0.24 10.9 6.7 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit YscO PF07321.12 EST48413.1 - 0.74 9.8 12.5 0.29 11.1 9.8 1.5 1 1 1 2 2 2 0 Type III secretion protein YscO Stap_Strp_tox_C PF02876.17 EST48414.1 - 0.018 15.3 0.6 0.018 15.3 0.6 1.7 2 0 0 2 2 2 0 Staphylococcal/Streptococcal toxin, beta-grasp domain TPH PF13868.6 EST48417.1 - 7.2e-17 60.9 118.5 7.2e-17 60.9 118.5 2.5 1 1 0 2 2 2 1 Trichohyalin-plectin-homology domain DHHC PF01529.20 EST48418.1 - 3.2e-22 79.1 8.2 3.2e-22 79.1 8.2 2.5 2 1 1 3 3 3 1 DHHC palmitoyltransferase VKOR PF07884.14 EST48418.1 - 1.6 8.9 12.9 0.52 10.5 1.9 2.4 2 0 0 2 2 2 0 Vitamin K epoxide reductase family TFIIA PF03153.13 EST48419.1 - 2.5 8.0 30.1 3 7.7 30.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RNA_pol_Rpb5_C PF01191.19 EST48420.1 - 1.8e-25 88.6 0.2 3.9e-25 87.5 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 EST48420.1 - 1.9e-06 28.4 0.1 6.5e-06 26.6 0.0 2.0 2 1 0 2 2 2 1 RNA polymerase Rpb5, N-terminal domain DRMBL PF07522.14 EST48420.1 - 0.0064 16.7 0.1 0.013 15.6 0.0 1.8 1 1 1 2 2 2 1 DNA repair metallo-beta-lactamase Phosphodiest PF01663.22 EST48421.1 - 1.3e-05 25.0 2.4 0.022 14.4 0.2 2.2 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EST48421.1 - 3.3e-05 23.4 1.8 0.0016 17.9 1.8 2.5 1 1 0 1 1 1 1 Sulfatase Band_7 PF01145.25 EST48422.1 - 1.7e-23 83.5 2.5 1.7e-23 83.5 2.5 1.9 2 1 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 EST48422.1 - 0.0029 17.3 0.2 0.0057 16.4 0.2 1.4 1 0 0 1 1 1 1 SPFH domain-Band 7 family TMEM18 PF14770.6 EST48423.1 - 2.6e-11 43.6 2.7 3.3e-11 43.2 2.7 1.1 1 0 0 1 1 1 1 Transmembrane protein 18 MtrE PF04206.12 EST48423.1 - 0.0085 15.5 1.2 0.0096 15.3 1.2 1.1 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, subunit E DUF1106 PF06523.11 EST48423.1 - 0.098 12.7 0.4 0.18 11.9 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1106) DHHC PF01529.20 EST48423.1 - 0.35 11.0 4.5 0.24 11.5 2.9 1.5 1 1 0 1 1 1 0 DHHC palmitoyltransferase DUF4761 PF15958.5 EST48424.1 - 0.11 12.7 0.0 0.38 10.9 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4761) FIVAR PF07554.13 EST48424.1 - 0.19 12.5 3.6 1.6 9.5 3.6 2.7 1 0 0 1 1 1 0 FIVAR domain NEMO PF11577.8 EST48424.1 - 0.34 11.0 2.8 0.28 11.2 0.2 2.2 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO KH_10 PF17905.1 EST48424.1 - 0.34 11.4 3.8 1.8 9.1 0.1 3.8 3 0 0 3 3 3 0 GLD-3 KH domain 5 Glyco_hydro_43 PF04616.14 EST48425.1 - 0.027 13.8 0.1 0.15 11.4 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolases family 43 HIT PF01230.23 EST48426.1 - 7.2e-24 84.4 1.2 9.2e-24 84.0 1.2 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EST48426.1 - 6.2e-17 62.1 1.2 7.6e-17 61.8 1.2 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding MotCF PF09158.10 EST48426.1 - 0.0012 18.8 0.2 0.002 18.2 0.2 1.4 1 0 0 1 1 1 1 Bacteriophage T4 MotA, C-terminal CwfJ_C_1 PF04677.15 EST48426.1 - 0.063 13.2 3.4 0.1 12.5 3.4 1.5 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 GalP_UDP_tr_C PF02744.17 EST48426.1 - 0.13 12.0 0.2 0.19 11.4 0.2 1.3 1 1 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain NYD-SP28 PF14772.6 EST48427.1 - 0.041 13.9 0.3 0.041 13.9 0.3 6.2 5 2 1 6 6 6 0 Sperm tail EIF_2_alpha PF07541.12 EST48428.1 - 1e-06 28.8 0.2 2.6e-06 27.5 0.1 1.8 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit Ras PF00071.22 EST48429.1 - 1.1e-55 187.6 0.3 1.3e-55 187.4 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EST48429.1 - 9.9e-35 119.4 0.2 1.7e-34 118.6 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EST48429.1 - 1.7e-13 50.4 0.1 2.2e-13 50.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EST48429.1 - 4.3e-05 23.0 0.2 5.9e-05 22.5 0.2 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EST48429.1 - 0.00013 22.0 0.0 0.00021 21.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EST48429.1 - 0.0027 17.6 1.3 1.2 9.1 0.2 2.3 1 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EST48429.1 - 0.0071 15.9 0.3 0.02 14.4 0.2 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MCM PF00493.23 EST48429.1 - 0.05 12.7 0.0 0.13 11.4 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain AAA_16 PF13191.6 EST48429.1 - 0.073 13.4 0.0 0.081 13.3 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Aa_trans PF01490.18 EST48430.1 - 4.5e-07 28.9 27.3 0.0023 16.7 22.0 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein MadM PF03818.13 EST48430.1 - 0.15 11.9 0.1 0.15 11.9 0.1 3.6 3 0 0 3 3 3 0 Malonate/sodium symporter MadM subunit Alpha_L_fucos PF01120.17 EST48431.1 - 0.01 15.3 4.4 0.021 14.3 4.4 1.5 1 0 0 1 1 1 0 Alpha-L-fucosidase Rhodanese PF00581.20 EST48432.1 - 2.3e-07 31.3 0.3 2.6e-06 27.9 0.3 2.0 1 1 0 1 1 1 1 Rhodanese-like domain zf-HC5HC2H_2 PF13832.6 EST48434.1 - 0.0025 18.0 1.9 0.0041 17.3 1.9 1.3 1 0 0 1 1 1 1 PHD-zinc-finger like domain Zf_RING PF16744.5 EST48434.1 - 0.065 13.3 3.5 4.9 7.3 0.1 2.3 1 1 1 2 2 2 0 KIAA1045 RING finger Mga PF05043.13 EST48434.1 - 0.074 13.6 0.9 0.15 12.6 0.1 1.9 2 0 0 2 2 2 0 Mga helix-turn-helix domain PHD PF00628.29 EST48434.1 - 0.22 11.4 7.6 0.44 10.5 7.6 1.5 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 EST48434.1 - 3.1 7.8 8.3 6.6 6.8 8.3 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 GAS PF13851.6 EST48438.1 - 0.052 12.9 18.6 0.082 12.2 18.6 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Peptidase_S41 PF03572.18 EST48438.1 - 0.12 11.9 0.2 0.18 11.3 0.2 1.3 1 0 0 1 1 1 0 Peptidase family S41 FlaC_arch PF05377.11 EST48438.1 - 0.16 12.4 3.9 1.7 9.1 0.2 3.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) GM_CSF PF01109.17 EST48438.1 - 0.16 12.1 2.2 0.43 10.8 1.4 2.0 1 1 1 2 2 2 0 Granulocyte-macrophage colony-stimulating factor CENP-F_leu_zip PF10473.9 EST48438.1 - 0.32 11.0 16.7 0.6 10.1 0.8 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HALZ PF02183.18 EST48438.1 - 0.8 10.0 5.6 18 5.6 0.2 3.8 2 1 1 3 3 3 0 Homeobox associated leucine zipper Allexi_40kDa PF05549.11 EST48438.1 - 4.7 6.7 11.6 6.5 6.2 10.3 1.7 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF4407 PF14362.6 EST48438.1 - 8 5.7 14.6 11 5.2 14.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Glyco_tran_28_C PF04101.16 EST48439.1 - 6.2e-13 49.1 0.0 9.2e-13 48.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Cnn_1N PF07989.11 EST48441.1 - 0.014 15.5 3.8 0.014 15.5 3.8 4.6 3 1 1 4 4 4 0 Centrosomin N-terminal motif 1 Latarcin PF10279.9 EST48441.1 - 1 9.8 6.9 3.1 8.3 1.4 3.1 2 0 0 2 2 2 0 Latarcin precursor Fe-ADH PF00465.19 EST48442.1 - 1e-65 221.9 0.0 1.2e-65 221.7 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EST48442.1 - 1.9e-08 34.3 0.4 2.7e-07 30.6 0.1 2.0 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase Aa_trans PF01490.18 EST48443.1 - 7.4e-10 38.1 35.8 5.3e-07 28.7 28.3 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Aa_trans PF01490.18 EST48444.1 - 4.9e-08 32.1 30.6 2.1e-05 23.4 23.3 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein GNAT_acetyltr_2 PF13718.6 EST48445.1 - 4.7e-61 206.1 0.7 2.7e-60 203.6 0.0 2.5 2 0 0 2 2 2 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.14 EST48445.1 - 1.9e-54 184.2 0.3 1.1e-52 178.5 0.0 2.6 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 EST48445.1 - 1.5e-26 92.2 0.1 5.6e-26 90.3 0.1 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.6 EST48445.1 - 4.2e-19 69.2 0.3 4.2e-19 69.2 0.3 3.5 3 0 0 3 3 3 1 Possible tRNA binding domain AAA_30 PF13604.6 EST48445.1 - 6.2e-05 22.8 0.1 0.00031 20.5 0.1 2.0 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 EST48445.1 - 0.0046 16.7 0.2 0.0046 16.7 0.2 2.9 3 1 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.15 EST48445.1 - 0.28 11.2 6.0 0.082 12.9 1.2 2.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit CTP_transf_like PF01467.26 EST48448.1 - 3.3e-11 43.6 0.0 4.8e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like Ribosomal_L13 PF00572.18 EST48453.1 - 0.028 14.7 0.7 0.028 14.7 0.7 1.8 2 0 0 2 2 2 0 Ribosomal protein L13 DUF3969 PF13108.6 EST48453.1 - 0.029 14.4 0.0 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3969) Dus PF01207.17 EST48454.1 - 5.6e-28 97.9 0.0 7.3e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) MnmE_helical PF12631.7 EST48456.1 - 0.59 10.3 6.8 1.7 8.7 6.8 1.8 1 0 0 1 1 1 0 MnmE helical domain Pex14_N PF04695.13 EST48457.1 - 0.011 16.4 0.9 0.014 16.0 0.9 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3464 PF11947.8 EST48457.1 - 0.023 14.5 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Het-C PF07217.11 EST48457.1 - 0.037 12.6 1.6 0.049 12.2 1.6 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Mx_ML PF17536.2 EST48457.1 - 0.054 13.2 0.2 0.069 12.9 0.1 1.3 1 1 0 1 1 1 0 Matrix and Matrix long proteins N-terminal DUF2956 PF11169.8 EST48457.1 - 0.058 13.6 3.3 0.085 13.1 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) DUF3671 PF12420.8 EST48457.1 - 0.087 12.9 2.7 0.17 12.0 2.7 1.4 1 1 0 1 1 1 0 Protein of unknown function Orf78 PF06024.12 EST48457.1 - 0.17 12.2 4.4 0.74 10.2 0.5 2.2 2 0 0 2 2 2 0 Orf78 (ac78) E1-E2_ATPase PF00122.20 EST48457.1 - 0.18 11.3 1.7 0.75 9.3 0.1 2.1 2 0 0 2 2 2 0 E1-E2 ATPase Pox_RNA_Pol_19 PF05320.12 EST48457.1 - 1.6 8.7 5.4 2.5 8.1 5.4 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Connexin PF00029.19 EST48457.1 - 3.7 7.3 7.5 0.11 12.2 0.9 1.7 2 0 0 2 2 2 0 Connexin DUF2207 PF09972.9 EST48457.1 - 5.4 5.7 6.1 1.1 8.0 0.1 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) COPI_assoc PF08507.10 EST48457.1 - 5.5 7.1 15.1 15 5.6 15.1 1.7 1 1 0 1 1 1 0 COPI associated protein FtsJ PF01728.19 EST48458.1 - 3.9e-61 206.2 0.1 4.5e-61 206.0 0.1 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 EST48458.1 - 0.11 12.1 0.1 0.27 10.9 0.1 1.8 1 1 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_23 PF13489.6 EST48458.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 EST48458.1 - 0.13 13.0 0.0 0.49 11.1 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain zf-CHY PF05495.12 EST48460.1 - 3.9e-07 30.5 19.1 3.9e-07 30.5 19.1 3.7 2 1 0 3 3 3 1 CHY zinc finger NTF2 PF02136.20 EST48461.1 - 5.5e-09 36.6 0.5 6.2e-09 36.5 0.5 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4518 PF15008.6 EST48461.1 - 0.22 10.7 0.5 0.34 10.0 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) FeS_assembly_P PF01883.19 EST48463.1 - 0.00082 19.5 0.0 0.0016 18.6 0.0 1.5 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein DUF4597 PF15366.6 EST48463.1 - 0.022 14.5 0.0 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4597) Metallophos PF00149.28 EST48464.1 - 0.00076 20.0 1.6 0.0013 19.3 1.6 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SIR2 PF02146.17 EST48465.1 - 8e-52 175.7 0.0 1.1e-51 175.2 0.0 1.2 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 EST48465.1 - 0.13 12.0 0.0 1.8 8.3 0.0 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain DHHC PF01529.20 EST48466.1 - 6e-28 97.6 11.8 6e-28 97.6 11.8 2.4 2 1 0 2 2 2 1 DHHC palmitoyltransferase Cadherin_C_2 PF16492.5 EST48466.1 - 0.71 10.7 3.9 6.7 7.5 1.0 2.4 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal UCH PF00443.29 EST48467.1 - 9.5e-24 84.3 4.3 1.6e-23 83.5 4.3 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EST48467.1 - 8.4e-19 67.7 21.5 6.9e-18 64.7 6.9 2.8 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 EST48467.1 - 1.8e-06 27.8 0.2 1.8e-06 27.8 0.2 3.2 2 2 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 EST48467.1 - 0.00012 21.8 11.2 0.018 14.8 5.8 2.7 2 0 0 2 2 2 2 Variant UBP zinc finger DUF2481 PF10654.9 EST48467.1 - 0.083 12.9 0.6 0.26 11.3 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2481) CENP-H PF05837.12 EST48468.1 - 0.95 9.9 25.7 0.48 10.9 6.3 2.7 1 1 1 2 2 2 0 Centromere protein H (CENP-H) eRF1_3 PF03465.15 EST48468.1 - 1.3 9.5 5.1 0.3 11.6 0.5 2.2 2 1 0 2 2 2 0 eRF1 domain 3 YabA PF06156.13 EST48468.1 - 2.5 8.8 25.5 6.4 7.5 6.4 3.2 1 1 2 3 3 3 0 Initiation control protein YabA GAS PF13851.6 EST48468.1 - 3.9 6.8 39.7 4.4 6.6 17.6 2.8 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding TCTP PF00838.17 EST48468.1 - 8.6 6.7 14.4 0.64 10.3 7.8 2.1 1 1 1 2 2 2 0 Translationally controlled tumour protein Rad52_Rad22 PF04098.15 EST48469.1 - 2e-31 109.0 0.0 2.6e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein ABC_tran PF00005.27 EST48470.1 - 3.1e-20 73.1 0.1 9.2e-20 71.6 0.1 1.8 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EST48470.1 - 1.1e-11 45.1 0.0 4.9e-06 26.6 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EST48470.1 - 3.6e-06 26.6 0.5 0.082 12.3 0.0 2.6 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EST48470.1 - 0.012 16.1 0.4 0.032 14.7 0.4 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EST48470.1 - 0.016 14.9 0.1 0.05 13.4 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 EST48470.1 - 0.016 15.6 0.0 0.045 14.2 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EST48470.1 - 0.016 15.5 0.1 0.041 14.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 EST48470.1 - 0.018 15.1 0.0 0.034 14.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 EST48470.1 - 0.046 12.9 1.4 0.13 11.4 0.1 2.0 1 1 1 2 2 2 0 NB-ARC domain NACHT PF05729.12 EST48470.1 - 0.079 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 EST48470.1 - 0.092 12.5 0.1 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EST48470.1 - 0.12 12.1 0.4 15 5.2 0.0 3.1 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase DUF2798 PF11391.8 EST48470.1 - 1.7 8.7 10.3 0.54 10.3 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2798) Tmemb_55A PF09788.9 EST48470.1 - 1.7 7.7 4.7 3.6 6.6 4.7 1.5 1 0 0 1 1 1 0 Transmembrane protein 55A Phage_TTP_13 PF16463.5 EST48471.1 - 0.17 11.4 0.1 0.46 10.0 0.0 1.7 2 0 0 2 2 2 0 Phage tail tube protein family DASH_Dad4 PF08650.10 EST48473.1 - 0.83 9.7 6.6 0.18 11.8 0.9 2.6 3 0 0 3 3 3 0 DASH complex subunit Dad4 VSP PF03302.13 EST48476.1 - 0.0023 16.9 22.9 0.0023 16.9 22.9 2.7 1 1 1 2 2 2 1 Giardia variant-specific surface protein DUF4748 PF15932.5 EST48476.1 - 0.17 11.6 1.1 0.32 10.8 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) DUF3042 PF11240.8 EST48476.1 - 1.4 9.0 4.3 3.2 7.8 4.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) Bacteriocin_IIc PF10439.9 EST48476.1 - 3 8.0 9.4 5.6 7.2 9.4 1.4 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Histone_H2A_C PF16211.5 EST48477.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 C-terminus of histone H2A PIG-P PF08510.12 EST48477.1 - 0.66 9.9 4.8 1.1 9.1 4.8 1.7 1 1 0 1 1 1 0 PIG-P VSP PF03302.13 EST48478.1 - 8e-05 21.7 0.4 8e-05 21.7 0.4 3.9 2 1 2 4 4 4 3 Giardia variant-specific surface protein DUF4748 PF15932.5 EST48478.1 - 0.19 11.5 1.2 0.42 10.4 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) PsbX PF06596.11 EST48478.1 - 2.2 8.3 7.0 3.6 7.7 7.0 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) VSP PF03302.13 EST48479.1 - 2.5e-05 23.3 41.3 2.5e-05 23.3 41.3 7.6 1 1 5 6 6 6 3 Giardia variant-specific surface protein FAD-oxidase_C PF02913.19 EST48481.1 - 0.041 13.5 0.1 0.063 12.9 0.1 1.3 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain Synaptobrevin PF00957.21 EST48481.1 - 0.25 11.1 1.2 0.4 10.5 1.2 1.3 1 0 0 1 1 1 0 Synaptobrevin CARM1 PF11531.8 EST48482.1 - 0.33 11.2 3.0 0.54 10.5 3.0 1.3 1 0 0 1 1 1 0 Coactivator-associated arginine methyltransferase 1 N terminal MAP7 PF05672.11 EST48482.1 - 0.46 10.2 24.6 0.61 9.8 24.6 1.2 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family DDRGK PF09756.9 EST48482.1 - 3.5 7.2 21.2 4.1 7.0 21.2 1.1 1 0 0 1 1 1 0 DDRGK domain DFP PF04127.15 EST48483.1 - 1.6e-52 178.1 0.8 2.5e-52 177.4 0.0 1.7 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein Flavoprotein PF02441.19 EST48483.1 - 6.1e-42 143.0 2.0 8.8e-42 142.5 2.0 1.2 1 0 0 1 1 1 1 Flavoprotein LSM PF01423.22 EST48484.1 - 4.9e-09 35.7 0.0 6.1e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain Ost5 PF05251.12 EST48485.1 - 0.12 12.7 1.7 0.2 11.9 1.7 1.4 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit 5 Pkinase PF00069.25 EST48487.1 - 6.6e-12 45.3 0.0 1e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EST48487.1 - 4e-10 40.0 0.6 3.1e-05 24.0 0.1 2.1 1 1 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EST48487.1 - 0.0001 21.7 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 EST48487.1 - 0.018 14.3 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Choline_kinase PF01633.20 EST48487.1 - 0.028 14.0 0.0 0.063 12.9 0.0 1.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase RIO1 PF01163.22 EST48487.1 - 0.039 13.6 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 EST48487.1 - 0.05 12.7 0.1 0.072 12.1 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Apolipoprotein PF01442.18 EST48489.1 - 0.00092 19.1 5.1 0.0013 18.7 4.1 1.7 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Lebercilin PF15619.6 EST48489.1 - 0.0096 15.6 17.5 0.28 10.8 6.2 2.2 1 1 0 2 2 2 2 Ciliary protein causing Leber congenital amaurosis disease DUF1465 PF07323.12 EST48489.1 - 0.46 10.3 5.2 0.39 10.5 1.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) CC2-LZ PF16516.5 EST48489.1 - 3.7 8.0 16.3 0.74 10.2 1.7 3.1 1 1 3 4 4 4 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Apolipoprotein PF01442.18 EST48490.1 - 0.00036 20.5 2.9 0.00057 19.8 2.5 1.5 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF1465 PF07323.12 EST48490.1 - 0.064 13.1 3.1 0.17 11.7 1.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) Lebercilin PF15619.6 EST48490.1 - 0.11 12.1 6.8 0.15 11.7 6.8 1.1 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF4482 PF14818.6 EST48490.1 - 0.59 11.0 6.2 7.7 7.4 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4482) IstB_IS21_ATP PF08483.11 EST48490.1 - 0.68 9.9 3.7 0.35 10.8 1.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding N-terminal MLD PF11647.8 EST48490.1 - 1.6 9.0 5.1 9.8 6.5 0.2 2.4 1 1 1 2 2 2 0 Membrane Localization Domain YabA PF06156.13 EST48490.1 - 1.8 9.3 6.2 0.61 10.8 1.8 2.0 1 1 1 2 2 2 0 Initiation control protein YabA XhlA PF10779.9 EST48490.1 - 2.9 8.2 6.1 8.9 6.6 1.3 2.3 1 1 1 2 2 2 0 Haemolysin XhlA Pkinase PF00069.25 EST48492.1 - 6.6e-12 45.3 0.0 1e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EST48492.1 - 4e-10 40.0 0.6 3.1e-05 24.0 0.1 2.1 1 1 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EST48492.1 - 0.0001 21.7 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 EST48492.1 - 0.018 14.3 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Choline_kinase PF01633.20 EST48492.1 - 0.028 14.0 0.0 0.063 12.9 0.0 1.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase RIO1 PF01163.22 EST48492.1 - 0.039 13.6 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 EST48492.1 - 0.05 12.7 0.1 0.072 12.1 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Ost5 PF05251.12 EST48495.1 - 0.12 12.7 1.7 0.2 11.9 1.7 1.4 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit 5 DFP PF04127.15 EST48496.1 - 1.6e-52 178.1 0.8 2.5e-52 177.4 0.0 1.7 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein Flavoprotein PF02441.19 EST48496.1 - 6.1e-42 143.0 2.0 8.8e-42 142.5 2.0 1.2 1 0 0 1 1 1 1 Flavoprotein CARM1 PF11531.8 EST48497.1 - 0.33 11.2 3.0 0.54 10.5 3.0 1.3 1 0 0 1 1 1 0 Coactivator-associated arginine methyltransferase 1 N terminal MAP7 PF05672.11 EST48497.1 - 0.46 10.2 24.6 0.61 9.8 24.6 1.2 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family DDRGK PF09756.9 EST48497.1 - 3.5 7.2 21.2 4.1 7.0 21.2 1.1 1 0 0 1 1 1 0 DDRGK domain FAD-oxidase_C PF02913.19 EST48498.1 - 0.041 13.5 0.1 0.063 12.9 0.1 1.3 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain Synaptobrevin PF00957.21 EST48498.1 - 0.25 11.1 1.2 0.4 10.5 1.2 1.3 1 0 0 1 1 1 0 Synaptobrevin Cupin_1 PF00190.22 EST48502.1 - 0.087 12.4 3.7 2 8.0 3.7 2.2 1 1 0 1 1 1 0 Cupin Plasmid_parti PF01672.16 EST48502.1 - 0.59 10.8 3.4 14 6.4 0.1 2.4 2 0 0 2 2 2 0 Putative plasmid partition protein HSP70 PF00012.20 EST48504.1 - 1.9e-231 769.4 11.7 2.2e-231 769.3 11.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EST48504.1 - 7.4e-14 51.3 0.1 1.5e-11 43.7 0.0 2.4 2 1 0 2 2 2 2 MreB/Mbl protein CdiA_C PF18451.1 EST48504.1 - 0.91 9.8 11.2 0.074 13.3 1.3 3.4 2 1 1 3 3 3 0 Contact-dependent growth inhibition CdiA C-terminal domain ALMT PF11744.8 EST48504.1 - 5.5 5.7 7.5 10 4.9 7.5 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter ACP53EA PF06313.11 EST48506.1 - 0.059 13.6 1.6 0.14 12.4 0.2 2.1 2 1 0 2 2 2 0 Drosophila ACP53EA protein Pkinase PF00069.25 EST48507.1 - 2.6e-69 233.5 0.0 3.6e-69 233.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST48507.1 - 3.8e-34 118.2 0.0 1.3e-33 116.4 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EST48507.1 - 1.2e-07 31.1 0.7 1.2e-07 31.1 0.7 2.1 2 1 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 EST48507.1 - 0.00038 19.9 0.0 0.0098 15.2 0.0 2.3 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 EST48507.1 - 0.0079 15.8 0.7 1.8 8.2 0.2 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Imm42 PF15593.6 EST48507.1 - 0.091 13.2 0.1 0.091 13.2 0.1 1.7 2 0 0 2 2 2 0 Immunity protein 42 Ribosomal_L27e PF01777.18 EST48508.1 - 2.1e-21 76.1 3.5 2.9e-21 75.6 3.5 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 EST48508.1 - 0.0063 16.4 1.3 0.011 15.6 1.3 1.4 1 0 0 1 1 1 1 KOW motif Ribosomal_S3Ae PF01015.18 EST48509.1 - 2.8e-56 190.3 5.2 3.5e-56 190.0 5.2 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 EST48509.1 - 0.059 12.9 0.1 0.25 10.9 0.0 2.0 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region HSP70 PF00012.20 EST48510.1 - 9.2e-35 119.9 0.1 1e-34 119.8 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein FtsA PF14450.6 EST48510.1 - 0.12 12.9 0.1 0.13 12.7 0.1 1.2 1 1 0 1 1 1 0 Cell division protein FtsA DEAD PF00270.29 EST48511.1 - 1.3e-37 129.2 0.0 2.3e-37 128.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EST48511.1 - 4e-27 94.8 0.7 1e-24 87.0 0.1 2.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EST48511.1 - 0.00027 20.2 0.1 0.021 14.1 0.0 2.2 1 1 1 2 2 2 2 ERCC3/RAD25/XPB C-terminal helicase NB-ARC PF00931.22 EST48511.1 - 0.15 11.2 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain PhoLip_ATPase_C PF16212.5 EST48512.1 - 7.8e-38 130.6 29.6 7.8e-38 130.6 29.6 3.0 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 EST48512.1 - 3e-12 47.3 0.3 0.00052 20.4 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase PhoLip_ATPase_N PF16209.5 EST48512.1 - 1.8e-11 43.6 3.4 1.8e-11 43.6 3.4 3.0 4 0 0 4 4 4 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 EST48512.1 - 1.9e-11 43.8 12.5 2.8e-11 43.3 0.2 3.3 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase PF13246.6 EST48512.1 - 1.2e-09 38.1 0.0 1.1e-07 31.8 0.0 2.7 2 0 0 2 2 2 1 Cation transport ATPase (P-type) GDA1_CD39 PF01150.17 EST48512.1 - 0.0021 16.8 2.8 0.031 13.0 0.1 2.2 2 0 0 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family PSI_PsaJ PF01701.18 EST48512.1 - 0.014 15.9 0.9 0.079 13.5 0.9 2.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ Hydrolase_3 PF08282.12 EST48512.1 - 0.027 14.2 0.1 0.027 14.2 0.1 3.7 4 1 0 4 4 4 0 haloacid dehalogenase-like hydrolase Cu PF17563.2 EST48514.1 - 0.064 13.5 0.2 0.14 12.4 0.2 1.5 1 0 0 1 1 1 0 Cupiennin Pkinase PF00069.25 EST48515.1 - 3.6e-57 193.7 0.1 5.9e-57 193.0 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST48515.1 - 2.8e-23 82.6 0.0 5.1e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EST48515.1 - 0.026 13.9 0.2 0.055 12.8 0.2 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EST48515.1 - 0.047 12.4 0.8 0.43 9.3 0.0 2.2 2 0 0 2 2 2 0 Fungal protein kinase LRRNT PF01462.18 EST48515.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain APH PF01636.23 EST48515.1 - 0.2 11.5 0.0 21 5.0 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family Ribosomal_S30 PF04758.14 EST48516.1 - 1.7e-15 57.0 0.9 2e-15 56.7 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S30 Prefoldin_2 PF01920.20 EST48517.1 - 1.1e-15 57.5 13.2 1.1e-15 57.5 13.2 1.3 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 EST48517.1 - 0.023 14.6 11.0 0.21 11.5 4.3 2.8 2 1 0 2 2 2 0 Prefoldin subunit TRPM_tetra PF16519.5 EST48517.1 - 0.025 14.7 0.5 0.025 14.7 0.5 2.7 3 1 0 3 3 3 0 Tetramerisation domain of TRPM GAS PF13851.6 EST48517.1 - 0.1 11.9 16.6 0.35 10.2 16.6 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding ArdA PF07275.11 EST48517.1 - 0.16 12.5 1.7 0.21 12.2 1.7 1.1 1 0 0 1 1 1 0 Antirestriction protein (ArdA) Ax_dynein_light PF10211.9 EST48517.1 - 0.22 11.4 11.4 0.14 12.1 9.1 1.6 1 1 1 2 2 2 0 Axonemal dynein light chain DUF4407 PF14362.6 EST48517.1 - 0.29 10.4 3.9 0.34 10.2 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DHR10 PF18595.1 EST48517.1 - 0.34 11.0 16.6 0.68 10.0 7.3 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Osmo_CC PF08946.10 EST48517.1 - 0.34 11.2 10.2 7.3 6.9 0.7 3.1 2 1 0 2 2 2 0 Osmosensory transporter coiled coil DASH_Dam1 PF08653.10 EST48517.1 - 0.42 10.4 3.8 4.5 7.1 0.1 2.6 3 0 0 3 3 3 0 DASH complex subunit Dam1 YlqD PF11068.8 EST48517.1 - 0.49 10.8 20.6 0.28 11.6 9.2 2.1 1 1 1 2 2 2 0 YlqD protein Spc24 PF08286.11 EST48517.1 - 1.3 9.3 11.2 3.9 7.8 0.9 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 FlaC_arch PF05377.11 EST48517.1 - 1.6 9.2 10.4 2.3 8.7 1.7 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) FapA PF03961.13 EST48517.1 - 1.8 7.1 10.5 2.2 6.8 10.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A YabA PF06156.13 EST48517.1 - 3.3 8.4 12.5 6.2 7.5 2.7 2.2 1 1 1 2 2 2 0 Initiation control protein YabA APG6_N PF17675.1 EST48517.1 - 7.1 7.2 16.4 45 4.6 16.4 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region Swi5 PF07061.11 EST48517.1 - 7.1 6.8 13.1 8.9 6.5 3.6 2.4 2 1 0 2 2 2 0 Swi5 DEAD PF00270.29 EST48518.1 - 5.1e-40 137.1 0.4 1e-39 136.1 0.4 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EST48518.1 - 6.1e-24 84.5 2.8 5.5e-23 81.4 0.8 3.1 3 1 0 3 3 3 1 Helicase conserved C-terminal domain CMS1 PF14617.6 EST48518.1 - 0.075 12.4 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Phostensin_N PF13916.6 EST48518.1 - 0.3 11.4 0.9 3.9 7.9 0.3 2.4 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal DUF1372 PF07116.11 EST48519.1 - 0.043 14.0 0.0 0.15 12.3 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1372) Flt3_lig PF02947.14 EST48519.1 - 0.31 11.2 4.3 0.37 11.0 0.6 3.0 3 0 0 3 3 3 0 flt3 ligand DUF667 PF05018.13 EST48520.1 - 3.6e-17 62.7 1.4 3.6e-17 62.7 1.4 3.4 3 1 0 3 3 3 1 Protein of unknown function (DUF667) PepSY_like PF11396.8 EST48520.1 - 0.064 13.8 9.7 0.22 12.1 0.8 4.3 3 0 0 3 3 3 0 Putative beta-lactamase-inhibitor-like, PepSY-like DNA_pol_A_exo1 PF01612.20 EST48521.1 - 5.8e-30 104.3 0.3 2.2e-29 102.4 0.1 2.1 2 0 0 2 2 2 1 3'-5' exonuclease Bromodomain PF00439.25 EST48522.1 - 1.2e-05 25.3 0.1 4e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Bromodomain Myb_DNA-bind_6 PF13921.6 EST48523.1 - 0.00098 19.3 0.0 0.0017 18.5 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain SNF2_assoc PF08455.10 EST48523.1 - 0.0037 16.4 0.3 0.0037 16.4 0.3 1.2 1 0 0 1 1 1 1 Bacterial SNF2 helicase associated Myb_DNA-binding PF00249.31 EST48523.1 - 0.017 15.3 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Death PF00531.22 EST48523.1 - 0.033 14.3 0.1 1.7 8.9 0.0 2.3 2 0 0 2 2 2 0 Death domain DNA_pol_B_exo1 PF03104.19 EST48525.1 - 5.8e-53 180.2 9.8 5.8e-53 180.2 9.8 3.0 3 0 0 3 3 3 1 DNA polymerase family B, exonuclease domain DUF1744 PF08490.12 EST48525.1 - 1.4e-11 43.7 11.9 5.2e-08 31.9 0.1 2.7 2 1 1 3 3 3 2 Domain of unknown function (DUF1744) DNA_pol_B PF00136.21 EST48525.1 - 3.1e-11 42.7 4.7 3e-10 39.4 1.3 3.2 2 1 0 2 2 2 1 DNA polymerase family B RNase_H_2 PF13482.6 EST48525.1 - 7.9e-05 22.7 1.5 0.00062 19.8 0.2 3.2 2 0 0 2 2 2 1 RNase_H superfamily DUF1758 PF05585.12 EST48525.1 - 0.045 13.5 1.4 4.8 6.9 0.0 3.3 3 0 0 3 3 3 0 Putative peptidase (DUF1758) Pkinase PF00069.25 EST48526.1 - 9.8e-36 123.5 0.1 3.2e-35 121.8 0.1 2.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST48526.1 - 1.8e-24 86.4 0.0 3.9e-24 85.3 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase HATPase_c PF02518.26 EST48526.1 - 6.4e-06 26.7 0.0 2.2e-05 24.9 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LytTR PF04397.15 EST48526.1 - 0.015 15.5 2.2 2.3 8.5 0.3 3.0 1 1 1 2 2 2 0 LytTr DNA-binding domain HATPase_c_5 PF14501.6 EST48526.1 - 0.024 14.5 0.1 0.29 11.1 0.0 2.7 2 0 0 2 2 2 0 GHKL domain Ribosomal_S25 PF03297.15 EST48526.1 - 0.95 9.7 3.9 0.34 11.1 0.3 2.1 2 0 0 2 2 2 0 S25 ribosomal protein Sec7 PF01369.20 EST48527.1 - 0.023 14.4 0.2 0.031 14.0 0.2 1.1 1 0 0 1 1 1 0 Sec7 domain Msg2_C PF12373.8 EST48527.1 - 0.081 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Major surface glycoprotein 2 C terminal Methyltransf_32 PF13679.6 EST48528.1 - 6e-17 62.1 0.1 1.6e-16 60.7 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EST48528.1 - 0.024 14.2 0.0 0.14 11.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain TRM13 PF05206.14 EST48528.1 - 0.034 13.7 1.8 0.52 9.8 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase TRM13 AAA_8 PF12780.7 EST48529.1 - 1.3e-92 309.8 0.1 4.4e-92 308.1 0.1 2.0 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.7 EST48529.1 - 6.5e-90 301.6 14.9 1.3e-89 300.6 14.9 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_C PF18199.1 EST48529.1 - 1.4e-86 290.5 0.8 5.6e-86 288.5 0.3 2.4 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 EST48529.1 - 1.4e-82 276.2 4.6 5.5e-82 274.1 4.6 2.2 1 0 0 1 1 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 EST48529.1 - 5.3e-62 208.5 1.6 2e-59 200.1 0.1 3.9 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EST48529.1 - 3.2e-51 173.4 0.5 6e-48 162.8 0.0 2.8 2 0 0 2 2 2 2 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EST48529.1 - 3e-33 114.4 0.0 4.2e-32 110.7 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_6 PF12774.7 EST48529.1 - 6.2e-26 91.1 2.5 1.8e-21 76.5 0.0 3.6 3 0 0 3 3 3 2 Hydrolytic ATP binding site of dynein motor region Dynein_AAA_lid PF17852.1 EST48529.1 - 2e-25 89.4 1.8 4.9e-25 88.1 0.2 2.6 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 EST48529.1 - 2.2e-25 88.8 0.3 9.9e-25 86.7 0.3 2.2 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EST48529.1 - 1.1e-18 67.6 0.0 3e-06 27.3 0.0 4.4 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EST48529.1 - 1.1e-06 29.2 0.1 0.016 15.6 0.0 5.1 3 1 1 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 EST48529.1 - 9.6e-05 22.7 0.0 0.7 10.2 0.0 4.7 4 0 0 4 4 4 1 AAA domain AAA PF00004.29 EST48529.1 - 0.00015 22.2 0.5 0.93 9.9 0.0 3.4 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 EST48529.1 - 0.0003 20.0 0.0 0.34 10.0 0.0 3.9 4 0 0 4 4 4 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 EST48529.1 - 0.0024 17.9 0.3 0.45 10.6 0.0 3.9 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 EST48529.1 - 0.0085 15.2 0.0 0.03 13.4 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_18 PF13238.6 EST48529.1 - 0.011 16.3 1.1 16 6.0 0.0 5.2 5 0 0 5 5 5 0 AAA domain AAA_25 PF13481.6 EST48529.1 - 0.017 14.7 0.1 0.28 10.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EST48529.1 - 0.11 12.9 1.1 4.2 7.8 0.0 3.5 3 0 0 3 3 3 0 RNA helicase ABC_tran PF00005.27 EST48529.1 - 0.15 12.6 1.3 12 6.4 0.0 4.1 4 0 0 4 4 3 0 ABC transporter NB-ARC PF00931.22 EST48529.1 - 0.27 10.4 2.8 0.56 9.3 0.0 2.9 4 0 0 4 4 4 0 NB-ARC domain SRP54 PF00448.22 EST48529.1 - 0.34 10.5 3.5 65 3.1 0.0 4.1 5 0 0 5 5 4 0 SRP54-type protein, GTPase domain NACHT PF05729.12 EST48529.1 - 0.49 10.3 3.0 2.4 8.1 0.0 3.6 4 0 0 4 4 3 0 NACHT domain COMMD1_N PF17221.3 EST48529.1 - 4.9 7.5 6.8 1.8 8.9 0.4 3.7 3 0 0 3 3 2 0 COMMD1 N-terminal domain AAA PF00004.29 EST48530.1 - 6.2e-32 110.8 0.0 2.1e-31 109.1 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EST48530.1 - 4.9e-08 32.7 0.0 1.3e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain IstB_IS21 PF01695.17 EST48530.1 - 0.033 13.9 0.3 0.39 10.4 0.0 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein Sec63 PF02889.16 EST48531.1 - 1.4e-48 165.3 9.2 1.3e-30 106.4 3.3 2.9 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EST48531.1 - 3.3e-48 163.8 3.5 1.1e-22 80.6 0.0 4.4 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 EST48531.1 - 1e-16 61.4 4.9 1.1e-08 35.3 0.0 3.6 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EST48531.1 - 2e-13 50.6 0.1 4.4e-06 27.0 0.1 3.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain T2SSE PF00437.20 EST48531.1 - 3e-05 23.2 0.0 0.066 12.3 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein PRP9_N PF16958.5 EST48531.1 - 0.94 9.5 12.1 0.36 10.8 7.7 2.6 2 0 0 2 2 2 0 Pre-mRNA-splicing factor PRP9 N-terminus DUF572 PF04502.13 EST48534.1 - 4.8 6.7 27.9 5.8 6.4 27.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Glyco_transf_10 PF00852.19 EST48535.1 - 0.02 14.6 0.1 0.025 14.3 0.1 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 10 (fucosyltransferase) C-term Syntaxin_2 PF14523.6 EST48536.1 - 0.013 15.9 0.8 0.013 15.9 0.8 2.0 1 1 1 2 2 2 0 Syntaxin-like protein DUF2682 PF10909.8 EST48536.1 - 0.017 15.6 3.7 1.8 9.1 0.6 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2682) MiaE PF06175.11 EST48536.1 - 0.05 13.2 0.1 0.08 12.5 0.1 1.4 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) PA26 PF04636.13 EST48537.1 - 0.0066 15.4 0.8 0.0098 14.9 0.8 1.3 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) Pkinase PF00069.25 EST48539.1 - 2.8e-41 141.6 0.0 7.4e-41 140.2 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST48539.1 - 3.9e-09 36.2 0.5 1.2e-08 34.5 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase L1R_F9L PF02442.17 EST48539.1 - 0.097 12.5 3.3 0.32 10.8 3.3 1.8 1 0 0 1 1 1 0 Lipid membrane protein of large eukaryotic DNA viruses SPC22 PF04573.12 EST48540.1 - 8.4e-15 54.7 6.6 8.9e-15 54.6 6.6 1.0 1 0 0 1 1 1 1 Signal peptidase subunit DUF630 PF04783.12 EST48542.1 - 0.079 13.1 0.0 1.4 9.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF630) Myb_DNA-binding PF00249.31 EST48543.1 - 5.8e-05 23.2 0.1 0.00011 22.3 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EST48543.1 - 0.0014 18.8 0.3 0.0014 18.8 0.3 2.0 2 1 0 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_6 PF13921.6 EST48543.1 - 0.01 16.1 1.0 0.024 14.9 0.1 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST48543.1 - 0.012 15.5 2.0 0.013 15.4 0.1 1.9 2 1 0 2 2 2 0 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 EST48543.1 - 0.24 11.8 3.8 1.1 9.7 0.6 2.7 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain RasGEF PF00617.19 EST48544.1 - 2.4e-13 50.7 0.0 6e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EST48544.1 - 8.8e-08 32.3 1.0 8.8e-08 32.3 1.0 2.7 2 1 1 3 3 3 1 RasGEF N-terminal motif DNA_mis_repair PF01119.19 EST48545.1 - 1.7e-11 43.8 2.9 4.3e-11 42.5 2.9 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 EST48545.1 - 0.00016 22.1 0.8 0.00062 20.3 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EST48545.1 - 0.0091 15.8 0.0 0.023 14.5 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Proteasome PF00227.26 EST48546.1 - 6.8e-40 136.6 0.0 8e-40 136.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit PROCT PF08084.11 EST48546.1 - 0.12 12.3 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 PROCT (NUC072) domain Med12-PQL PF12144.8 EST48547.1 - 0.31 10.9 6.8 0.11 12.4 4.1 1.6 2 0 0 2 2 2 0 Eukaryotic Mediator 12 catenin-binding domain HYLS1_C PF15311.6 EST48549.1 - 0.00087 20.0 1.9 0.00087 20.0 1.9 2.9 2 1 1 3 3 3 1 Hydrolethalus syndrome protein 1 C-terminus Tau95 PF09734.9 EST48549.1 - 2.7 8.8 11.1 0.58 11.0 3.3 2.2 2 0 0 2 2 2 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain DUF1348 PF07080.11 EST48550.1 - 0.037 13.9 1.1 0.078 12.9 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1348) SIKE PF05769.11 EST48551.1 - 0.0028 17.6 7.9 0.0028 17.6 7.9 2.1 2 0 0 2 2 2 1 SIKE family DUF148 PF02520.17 EST48551.1 - 0.0084 16.2 9.8 0.0084 16.2 9.8 2.4 1 1 1 2 2 2 1 Domain of unknown function DUF148 RasGAP_C PF03836.15 EST48551.1 - 0.022 14.9 13.6 0.067 13.3 7.3 2.4 2 0 0 2 2 2 0 RasGAP C-terminus YkyA PF10368.9 EST48551.1 - 0.027 14.2 21.2 0.13 11.9 21.3 1.9 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein bZIP_1 PF00170.21 EST48551.1 - 0.044 13.9 2.1 0.044 13.9 2.1 2.8 2 1 1 3 3 3 0 bZIP transcription factor HAUS6_N PF14661.6 EST48551.1 - 0.11 12.0 6.0 0.16 11.5 6.0 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Cytochrom_C_2 PF01322.20 EST48551.1 - 0.14 13.1 2.5 0.26 12.2 2.1 1.7 2 0 0 2 2 2 0 Cytochrome C' DUF1515 PF07439.11 EST48551.1 - 0.25 11.4 2.8 0.57 10.2 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DUF1759 PF03564.15 EST48551.1 - 0.27 11.1 7.3 0.1 12.5 2.5 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1759) Baculo_PEP_C PF04513.12 EST48551.1 - 0.46 10.5 9.4 0.18 11.9 2.9 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3450 PF11932.8 EST48551.1 - 1.1 8.5 12.7 2 7.6 12.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF1664 PF07889.12 EST48551.1 - 1.5 8.9 15.1 0.13 12.3 9.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.8 EST48551.1 - 2.5 8.2 22.2 0.46 10.5 5.5 3.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Seryl_tRNA_N PF02403.22 EST48551.1 - 3.1 8.1 19.8 0.16 12.2 12.5 2.4 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Vir_act_alpha_C PF10400.9 EST48551.1 - 6.8 7.5 7.9 57 4.5 5.2 3.0 2 1 0 2 2 2 0 Virulence activator alpha C-term DUF4239 PF14023.6 EST48551.1 - 7.3 6.2 8.0 11 5.6 0.3 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF4239) PCRF PF03462.18 EST48551.1 - 8.9 6.1 14.1 2.3 8.0 8.3 2.2 2 1 0 2 2 2 0 PCRF domain CYTH PF01928.21 EST48553.1 - 8.3e-12 45.4 0.8 9.4e-12 45.2 0.8 1.0 1 0 0 1 1 1 1 CYTH domain DUF5121 PF17165.4 EST48554.1 - 0.13 12.7 1.9 0.8 10.2 0.1 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF5121) Thioredoxin PF00085.20 EST48556.1 - 1.1e-20 73.6 0.4 1.2e-20 73.4 0.4 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EST48556.1 - 0.0018 18.7 0.2 0.0036 17.7 0.2 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain GRP PF07172.11 EST48558.1 - 0.001 19.7 8.7 0.0096 16.6 8.7 2.8 1 0 0 1 1 1 1 Glycine rich protein family ATG16 PF08614.11 EST48558.1 - 0.018 15.3 22.3 0.018 15.3 22.3 5.0 1 1 4 5 5 5 0 Autophagy protein 16 (ATG16) PKcGMP_CC PF16808.5 EST48558.1 - 0.029 14.2 0.2 0.029 14.2 0.2 4.4 6 0 0 6 6 6 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Atg14 PF10186.9 EST48558.1 - 3 6.8 105.4 3.4 6.7 18.9 4.5 1 1 3 4 4 4 0 Vacuolar sorting 38 and autophagy-related subunit 14 EF-hand_8 PF13833.6 EST48559.1 - 0.02 14.7 0.8 2.2 8.2 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain pair Ribosomal_S24e PF01282.19 EST48559.1 - 0.051 13.5 0.0 0.079 12.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S24e A_deaminase PF00962.22 EST48559.1 - 0.13 11.6 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Adenosine/AMP deaminase Vps4_C PF09336.10 EST48559.1 - 0.13 12.3 0.0 2 8.5 0.0 2.3 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain Nop PF01798.18 EST48560.1 - 8.9e-56 188.9 2.4 1.6e-55 188.1 2.4 1.3 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EST48560.1 - 0.0022 18.3 0.1 0.0081 16.5 0.1 2.0 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Pkinase PF00069.25 EST48562.1 - 3.9e-27 95.3 0.0 7.5e-27 94.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST48562.1 - 1.1e-09 38.0 0.0 3.9e-09 36.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EST48562.1 - 0.00098 19.1 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EST48562.1 - 0.0038 16.6 0.1 0.0067 15.8 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EST48562.1 - 0.0045 16.3 0.0 0.022 14.1 0.0 2.1 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EST48562.1 - 0.0052 15.8 0.4 0.0082 15.1 0.4 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 EST48562.1 - 0.053 13.1 0.0 0.12 12.0 0.0 1.7 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 LRR_6 PF13516.6 EST48563.1 - 4.4e-15 54.4 35.9 0.0032 17.4 0.4 10.8 11 0 0 11 11 11 6 Leucine Rich repeat LRR_4 PF12799.7 EST48563.1 - 0.00033 21.0 41.7 0.32 11.5 1.4 7.6 5 1 0 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EST48563.1 - 0.021 15.3 23.0 5.6 7.9 0.4 9.4 7 1 0 7 7 7 0 Leucine Rich Repeat Hypoth_Ymh PF09509.10 EST48563.1 - 0.12 12.2 3.9 3.1 7.7 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (Hypoth_ymh) DEDD_Tnp_IS110 PF01548.17 EST48563.1 - 0.12 12.2 2.1 0.19 11.6 0.0 2.4 3 0 0 3 3 3 0 Transposase Ank_2 PF12796.7 EST48564.1 - 3.6e-05 24.3 0.1 0.025 15.2 0.0 2.4 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EST48564.1 - 9.6e-05 22.9 0.0 0.03 14.9 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EST48564.1 - 0.0011 19.3 0.1 0.21 12.2 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 EST48564.1 - 0.064 13.6 0.0 18 5.8 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) GrpE PF01025.19 EST48567.1 - 2e-11 43.9 0.7 5.6e-11 42.4 0.7 1.8 1 1 0 1 1 1 1 GrpE Med20 PF08612.11 EST48568.1 - 0.0059 16.0 2.1 0.0059 16.0 2.1 2.0 2 0 0 2 2 2 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex DUF2594 PF10769.9 EST48569.1 - 0.13 12.3 2.6 1.2 9.3 2.6 2.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2594) K1 PF02960.14 EST48569.1 - 0.18 12.0 2.5 29 4.8 0.1 4.0 3 0 0 3 3 3 0 K1 glycoprotein RNase_J_C PF17770.1 EST48569.1 - 3 9.0 5.1 5.9 8.0 0.2 4.5 3 0 0 3 3 3 0 Ribonuclease J C-terminal domain Tubulin PF00091.25 EST48570.1 - 4.1e-65 219.7 0.0 8e-65 218.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EST48570.1 - 1.3e-33 115.8 0.1 2.4e-31 108.5 0.1 2.5 1 1 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EST48570.1 - 2.2e-05 24.7 0.1 0.00012 22.3 0.0 2.4 2 1 0 2 2 2 1 Misato Segment II tubulin-like domain Stealth_CR3 PF17102.5 EST48570.1 - 0.079 12.9 0.2 2 8.4 0.0 2.7 3 0 0 3 3 3 0 Stealth protein CR3, conserved region 3 DUF4451 PF14616.6 EST48570.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) Peptidase_C50 PF03568.17 EST48571.1 - 0.013 14.6 1.5 0.021 14.0 1.3 1.5 1 1 0 1 1 1 0 Peptidase family C50 HTH_7 PF02796.15 EST48571.1 - 0.031 14.3 0.0 0.37 10.9 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase EF-hand_3 PF09069.11 EST48571.1 - 0.11 12.9 1.6 0.28 11.6 0.3 2.2 2 1 0 2 2 2 0 EF-hand HTH_29 PF13551.6 EST48571.1 - 0.15 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix Cpn60_TCP1 PF00118.24 EST48572.1 - 7.9e-155 516.2 1.5 9.8e-155 515.9 1.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PhyH PF05721.13 EST48573.1 - 0.093 13.0 0.0 0.1 12.8 0.0 1.1 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) DUF5462 PF17547.2 EST48573.1 - 0.13 11.6 0.2 0.19 11.1 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5462) Enkurin PF13864.6 EST48574.1 - 3.1e-13 50.0 4.7 3.1e-13 50.0 4.7 2.9 2 1 1 3 3 3 1 Calmodulin-binding LpxI_N PF17930.1 EST48574.1 - 0.045 13.7 0.2 10 6.0 0.0 2.5 2 0 0 2 2 2 0 LpxI N-terminal domain RNA_pol_Rpb1_2 PF00623.20 EST48575.1 - 0.18 12.1 0.5 0.27 11.5 0.5 1.3 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 2 zf-B_box PF00643.24 EST48576.1 - 7.4 6.8 16.3 32 4.8 16.3 2.0 1 1 0 1 1 1 0 B-box zinc finger Myb_DNA-binding PF00249.31 EST48577.1 - 4.7e-06 26.7 1.4 0.00058 20.0 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST48577.1 - 1.5e-05 25.2 8.7 1.9e-05 24.8 3.5 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain DUF4488 PF14869.6 EST48577.1 - 0.014 15.3 0.4 0.38 10.7 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4488) KptA_kDCL PF18176.1 EST48577.1 - 0.053 13.4 0.1 0.064 13.1 0.1 1.3 1 0 0 1 1 1 0 KptA in kinetoplastid DICER domain HTH_AsnC-type PF13404.6 EST48577.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain DUF2304 PF10066.9 EST48578.1 - 0.013 15.8 3.5 0.019 15.2 3.5 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) Maelstrom PF13017.6 EST48578.1 - 0.019 14.7 0.1 0.021 14.5 0.1 1.1 1 0 0 1 1 1 0 piRNA pathway germ-plasm component PigN PF04987.14 EST48578.1 - 0.022 13.7 6.9 0.041 12.8 6.9 1.5 1 1 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) CcmF_C PF16327.5 EST48578.1 - 0.041 13.2 0.1 0.049 12.9 0.1 1.0 1 0 0 1 1 1 0 Cytochrome c-type biogenesis protein CcmF C-terminal SlyX PF04102.12 EST48578.1 - 0.078 13.6 0.6 0.13 12.9 0.6 1.2 1 0 0 1 1 1 0 SlyX CoA_binding_3 PF13727.6 EST48578.1 - 0.14 12.1 1.5 0.23 11.5 1.5 1.5 1 1 0 1 1 1 0 CoA-binding domain MHC2-interact PF09307.10 EST48578.1 - 0.55 10.2 1.8 0.4 10.7 0.2 1.6 2 0 0 2 2 2 0 CLIP, MHC2 interacting DivIC PF04977.15 EST48578.1 - 1.4 8.8 7.4 0.42 10.4 2.4 2.1 2 0 0 2 2 2 0 Septum formation initiator DUF997 PF06196.12 EST48579.1 - 0.097 12.7 4.3 0.14 12.2 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF997) ThiC_Rad_SAM PF01964.18 EST48579.1 - 0.11 11.3 1.7 0.13 11.0 1.7 1.1 1 0 0 1 1 1 0 Radical SAM ThiC family LRR_8 PF13855.6 EST48580.1 - 5.9e-27 93.2 43.0 8e-06 25.5 1.3 9.0 2 2 5 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 EST48580.1 - 3.2e-22 78.3 57.3 6.6e-05 23.2 0.9 11.0 3 2 5 10 10 10 8 Leucine Rich repeats (2 copies) Pecanex_C PF05041.15 EST48581.1 - 2.4e-13 50.2 0.1 4.9e-13 49.2 0.1 1.5 1 0 0 1 1 1 1 Pecanex protein (C-terminus) Osmo_CC PF08946.10 EST48583.1 - 0.053 13.8 0.3 0.053 13.8 0.3 2.9 4 1 0 4 4 4 0 Osmosensory transporter coiled coil BPS1 PF05633.11 EST48583.1 - 0.057 12.4 1.4 0.075 12.0 1.4 1.2 1 0 0 1 1 1 0 Protein BYPASS1-related Ppx-GppA PF02541.16 EST48583.1 - 0.081 12.4 0.7 0.13 11.7 0.5 1.4 2 0 0 2 2 2 0 Ppx/GppA phosphatase family PRKG1_interact PF15898.5 EST48586.1 - 0.022 15.7 1.1 0.022 15.7 1.1 2.9 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Exonuc_VII_L PF02601.15 EST48586.1 - 3.5 7.1 15.0 4.5 6.8 15.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF948 PF06103.11 EST48586.1 - 4.6 7.6 6.8 3.7e+02 1.5 6.8 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) MiaE PF06175.11 EST48587.1 - 0.0011 18.7 0.8 0.0016 18.1 0.8 1.2 1 0 0 1 1 1 1 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) Cloacin_immun PF03513.14 EST48587.1 - 0.031 14.6 0.4 7.3 7.0 0.1 2.5 2 0 0 2 2 2 0 Cloacin immunity protein Matrilin_ccoil PF10393.9 EST48587.1 - 0.052 13.4 4.6 0.81 9.6 0.2 3.5 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin HD_4 PF13328.6 EST48587.1 - 0.059 13.1 0.6 0.092 12.5 0.6 1.5 1 0 0 1 1 1 0 HD domain DUF4164 PF13747.6 EST48587.1 - 0.077 13.3 4.8 0.48 10.7 0.5 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Fzo_mitofusin PF04799.13 EST48587.1 - 0.1 12.1 12.7 1.1 8.7 2.8 2.6 1 1 1 2 2 2 0 fzo-like conserved region BLOC1_2 PF10046.9 EST48587.1 - 0.46 10.8 22.8 0.07 13.4 4.0 4.3 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 EST48587.1 - 0.54 10.3 15.9 0.68 10.0 4.2 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) LXG PF04740.12 EST48587.1 - 1.2 8.7 18.5 0.048 13.4 9.3 2.8 2 1 1 3 3 3 0 LXG domain of WXG superfamily Sec2p PF06428.11 EST48587.1 - 2.7 8.0 11.1 0.79 9.7 1.6 3.0 3 1 0 3 3 3 0 GDP/GTP exchange factor Sec2p HIP1_clath_bdg PF16515.5 EST48587.1 - 5.2 7.7 16.5 2.8 8.6 7.4 3.4 2 2 2 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Ribosomal_L29e PF01779.17 EST48588.1 - 4e-08 33.5 8.3 4.9e-08 33.2 8.3 1.1 1 0 0 1 1 1 1 Ribosomal L29e protein family Dynein_light PF01221.18 EST48589.1 - 6.6e-29 100.1 0.7 7.4e-29 99.9 0.7 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Phage_sheath_1N PF17481.2 EST48589.1 - 0.025 15.0 0.2 0.032 14.7 0.2 1.2 1 0 0 1 1 1 0 Phage tail sheath protein beta-sandwich domain PHM7_cyt PF14703.6 EST48590.1 - 0.0039 17.4 12.0 0.0039 17.4 12.0 1.5 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Spectrin PF00435.21 EST48590.1 - 0.075 13.5 20.5 0.36 11.3 1.4 3.4 1 1 1 3 3 3 0 Spectrin repeat DUF2433 PF10360.9 EST48590.1 - 0.084 13.0 12.1 0.19 11.9 0.2 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2433) DUF4407 PF14362.6 EST48590.1 - 0.5 9.7 16.4 0.73 9.1 3.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) HIP1_clath_bdg PF16515.5 EST48590.1 - 0.6 10.7 29.4 0.41 11.3 12.2 2.9 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Cep57_CLD_2 PF14197.6 EST48590.1 - 0.64 10.2 10.6 1.7 8.8 1.8 3.0 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 KASH_CCD PF14662.6 EST48590.1 - 0.78 9.5 33.9 2.4 7.9 9.4 3.0 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH Cor1 PF04803.12 EST48590.1 - 6.8 6.9 35.1 0.074 13.3 5.8 3.1 1 1 2 3 3 3 0 Cor1/Xlr/Xmr conserved region Clat_adaptor_s PF01217.20 EST48591.1 - 2.4e-44 150.7 2.7 2.7e-44 150.6 2.7 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Arf PF00025.21 EST48592.1 - 4.7e-74 247.6 0.1 5.3e-74 247.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EST48592.1 - 6.4e-17 61.7 0.3 3.3e-13 49.5 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EST48592.1 - 3.2e-14 53.2 0.0 4.5e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EST48592.1 - 2.3e-12 46.8 0.0 2.7e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EST48592.1 - 6.2e-12 45.3 0.0 7.6e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EST48592.1 - 5.3e-10 39.1 0.0 6.7e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EST48592.1 - 4.8e-06 26.6 0.0 7.4e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EST48592.1 - 0.0006 19.2 0.0 0.00089 18.6 0.0 1.3 1 1 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.27 EST48592.1 - 0.005 16.4 0.3 0.024 14.2 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain NACHT PF05729.12 EST48592.1 - 0.0067 16.4 0.4 0.037 14.0 0.0 2.0 2 0 0 2 2 2 1 NACHT domain cobW PF02492.19 EST48592.1 - 0.0086 15.7 0.2 0.13 11.8 0.0 2.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 EST48592.1 - 0.044 14.3 0.3 0.14 12.6 0.2 1.6 1 1 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 EST48592.1 - 0.077 12.6 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 EST48592.1 - 0.13 12.1 0.0 0.25 11.3 0.0 1.4 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 EST48592.1 - 0.17 12.1 0.1 0.24 11.5 0.1 1.4 1 1 0 1 1 1 0 AAA domain HTH_47 PF16221.5 EST48593.1 - 0.04 13.5 0.3 0.13 11.8 0.1 1.9 1 1 1 2 2 2 0 winged helix-turn-helix Duffy_binding PF05424.11 EST48594.1 - 0.048 13.7 0.5 0.11 12.5 0.5 1.6 1 0 0 1 1 1 0 Duffy binding domain PTPS PF01242.19 EST48594.1 - 0.35 10.8 1.3 0.63 10.0 0.3 1.9 2 0 0 2 2 2 0 6-pyruvoyl tetrahydropterin synthase LRR_8 PF13855.6 EST48596.1 - 0.00041 20.1 1.9 0.00091 18.9 1.8 1.7 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 EST48596.1 - 0.049 14.1 0.6 0.1 13.0 0.6 1.6 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) EF-hand_7 PF13499.6 EST48597.1 - 0.039 14.4 0.1 0.64 10.5 0.1 2.4 1 1 0 1 1 1 0 EF-hand domain pair OSK PF17182.4 EST48597.1 - 0.057 12.7 0.1 0.07 12.4 0.1 1.1 1 0 0 1 1 1 0 OSK domain DUF3082 PF11282.8 EST48598.1 - 0.033 14.4 0.9 0.12 12.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3082) MCM PF00493.23 EST48599.1 - 5e-86 287.4 0.1 9.6e-86 286.5 0.1 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 EST48599.1 - 1e-21 77.2 0.8 2.6e-21 75.8 0.8 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 EST48599.1 - 4e-11 42.8 5.5 1.8e-10 40.7 5.5 2.1 1 1 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 EST48599.1 - 9e-10 38.3 0.0 8.4e-08 31.8 0.0 2.5 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EST48599.1 - 1.8e-07 31.2 0.0 4.7e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EST48599.1 - 2.6e-05 24.1 0.1 0.00022 21.1 0.0 2.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EST48599.1 - 0.0046 16.7 0.0 0.02 14.6 0.0 2.0 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase_C PF13335.6 EST48599.1 - 0.022 15.4 0.6 0.11 13.1 0.1 2.4 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal Zn-ribbon_8 PF09723.10 EST48599.1 - 0.072 13.2 1.1 0.2 11.8 1.1 1.7 1 0 0 1 1 1 0 Zinc ribbon domain DSPc PF00782.20 EST48600.1 - 2.8e-28 98.4 0.8 1.4e-27 96.1 0.2 2.5 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 EST48600.1 - 0.052 13.2 0.0 0.15 11.7 0.0 1.8 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Reticulon PF02453.17 EST48601.1 - 0.02 14.9 9.1 0.04 13.9 9.1 1.6 1 1 0 1 1 1 0 Reticulon COX6C PF02937.15 EST48601.1 - 0.037 14.2 2.5 0.15 12.2 0.9 2.6 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIc Fip1 PF05182.13 EST48602.1 - 3e-05 23.4 0.4 7.5e-05 22.2 0.4 1.7 1 0 0 1 1 1 1 Fip1 motif ArfGap PF01412.18 EST48603.1 - 3.2e-21 75.6 0.9 3.2e-21 75.6 0.9 2.7 2 1 0 2 2 2 1 Putative GTPase activating protein for Arf zf-B_box PF00643.24 EST48603.1 - 0.15 12.2 0.8 0.27 11.4 0.8 1.4 1 0 0 1 1 1 0 B-box zinc finger Ribosomal_L14 PF00238.19 EST48605.1 - 2.8e-34 117.8 0.0 3.4e-34 117.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e PAS_3 PF08447.12 EST48605.1 - 0.064 13.6 0.0 0.093 13.0 0.0 1.2 1 0 0 1 1 1 0 PAS fold EF-hand_7 PF13499.6 EST48606.1 - 1.9e-05 25.0 0.1 0.00027 21.3 0.1 2.6 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EST48606.1 - 3.5e-05 23.4 0.0 0.0037 17.1 0.0 3.2 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.32 EST48606.1 - 7e-05 22.1 0.1 0.00052 19.4 0.0 2.5 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 EST48606.1 - 0.031 14.1 0.0 0.23 11.3 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair DUF5314 PF17241.2 EST48606.1 - 0.053 13.2 0.0 0.097 12.3 0.0 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5314) Ribosom_S12_S23 PF00164.25 EST48608.1 - 1.3e-39 134.4 0.4 1.7e-39 133.9 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Flavodoxin_1 PF00258.25 EST48609.1 - 2.6e-08 34.2 0.0 3e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin AAA_35 PF14516.6 EST48609.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain HipA_C PF07804.12 EST48609.1 - 0.16 11.6 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 HipA-like C-terminal domain Ham1p_like PF01725.16 EST48611.1 - 2.5e-39 135.1 0.0 4.7e-39 134.2 0.0 1.5 1 0 0 1 1 1 1 Ham1 family Methyltransf_31 PF13847.6 EST48612.1 - 7.9e-16 58.2 0.3 1.2e-15 57.7 0.3 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EST48612.1 - 3.4e-14 53.0 0.0 4.2e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EST48612.1 - 1.2e-13 51.6 0.1 4.7e-13 49.7 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EST48612.1 - 1.4e-13 51.3 0.1 2.7e-13 50.4 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EST48612.1 - 2.2e-13 50.8 0.0 3.7e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EST48612.1 - 1.1e-07 31.5 0.1 1.6e-07 31.0 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EST48612.1 - 4.7e-07 29.5 0.0 1.2e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 EST48612.1 - 4.4e-06 26.5 0.0 5.8e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_2 PF00891.18 EST48612.1 - 0.00011 21.6 0.0 0.00015 21.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain PrmA PF06325.13 EST48612.1 - 0.00068 19.1 0.0 0.001 18.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.14 EST48612.1 - 0.0011 18.4 0.1 0.0022 17.5 0.1 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_18 PF12847.7 EST48612.1 - 0.016 15.2 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_5 PF01795.19 EST48612.1 - 0.023 14.2 0.1 1.4 8.3 0.0 2.2 1 1 1 2 2 2 0 MraW methylase family CheR PF01739.18 EST48612.1 - 0.04 13.4 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain MetW PF07021.12 EST48612.1 - 0.05 13.2 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 EST48612.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Neurexophilin PF06312.12 EST48612.1 - 0.41 10.1 4.2 0.91 8.9 0.2 2.3 1 1 1 2 2 2 0 Neurexophilin Methyltransf_23 PF13489.6 EST48613.1 - 7.7e-16 58.4 0.0 1e-15 58.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EST48613.1 - 5.2e-15 56.0 0.0 8e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EST48613.1 - 2.2e-12 47.0 0.1 5e-12 45.9 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EST48613.1 - 7.5e-12 45.7 0.0 1.6e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EST48613.1 - 5.1e-11 43.1 0.0 8.7e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EST48613.1 - 1.8e-06 27.5 0.1 2.7e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EST48613.1 - 2.7e-05 23.8 0.0 6.7e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain TehB PF03848.14 EST48613.1 - 0.00079 18.9 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_2 PF00891.18 EST48613.1 - 0.0036 16.6 0.0 0.0046 16.3 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain MetW PF07021.12 EST48613.1 - 0.0073 15.9 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.7 EST48613.1 - 0.009 16.0 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EST48613.1 - 0.015 14.7 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 EST48613.1 - 0.047 13.0 0.0 0.087 12.1 0.0 1.5 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase RrnaAD PF00398.20 EST48613.1 - 0.1 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Adaptin_N PF01602.20 EST48614.1 - 9.3e-87 291.7 20.1 1.8e-86 290.8 20.1 1.4 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EST48614.1 - 1.4e-39 135.7 3.1 1.4e-39 135.7 3.1 3.2 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EST48614.1 - 1.4e-09 38.2 3.0 3.1e-05 24.3 0.1 5.1 2 1 3 5 5 5 2 HEAT repeats HEAT PF02985.22 EST48614.1 - 3.6e-07 29.9 9.1 0.011 15.9 0.1 6.4 8 0 0 8 8 8 2 HEAT repeat HEAT_EZ PF13513.6 EST48614.1 - 0.0025 18.3 0.5 1.4 9.5 0.0 3.9 3 1 0 3 3 3 1 HEAT-like repeat Arm PF00514.23 EST48614.1 - 0.019 15.0 3.7 25 5.1 0.0 4.7 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF5071 PF16804.5 EST48614.1 - 0.031 14.6 3.5 0.036 14.3 0.3 2.8 4 0 0 4 4 4 0 Domain of unknown function (DUF5071) YihI PF04220.12 EST48614.1 - 0.081 12.6 0.2 0.2 11.3 0.2 1.6 1 0 0 1 1 1 0 Der GTPase activator (YihI) Caskin-tail PF16632.5 EST48614.1 - 0.14 12.6 2.1 1.3 9.5 0.2 3.3 2 1 0 2 2 2 0 C-terminal region of Caskin API5 PF05918.11 EST48614.1 - 0.15 10.9 3.9 0.85 8.3 0.5 2.3 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) FAS_N PF17828.1 EST48615.1 - 0.00088 19.3 1.9 0.00088 19.3 1.9 3.6 3 1 1 4 4 4 1 N-terminal domain in fatty acid synthase subunit beta Myb_DNA-bind_5 PF13873.6 EST48615.1 - 0.011 15.8 2.0 0.057 13.5 2.0 2.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Gly_acyl_tr_C PF08444.10 EST48615.1 - 0.12 12.6 1.0 26 5.1 0.0 3.3 2 0 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region MCR_beta PF02241.18 EST48615.1 - 0.14 11.7 0.9 0.19 11.3 0.2 1.6 2 0 0 2 2 2 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain SpecificRecomb PF10136.9 EST48615.1 - 0.17 10.2 10.1 0.24 9.6 10.1 1.3 1 1 0 1 1 1 0 Site-specific recombinase Bcr-Abl_Oligo PF09036.10 EST48615.1 - 0.36 10.9 2.1 3.4 7.8 0.1 2.8 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain HrpB7 PF09486.10 EST48615.1 - 0.38 11.1 2.2 5.9 7.3 0.1 2.5 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) CENP-F_leu_zip PF10473.9 EST48615.1 - 0.49 10.4 27.6 0.066 13.2 14.4 3.1 1 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF730 PF05325.11 EST48615.1 - 0.52 10.3 4.1 23 5.0 0.1 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF730) SlyX PF04102.12 EST48615.1 - 3 8.5 32.0 2.8 8.6 1.4 5.2 2 1 2 4 4 4 0 SlyX FANCI_S2 PF14676.6 EST48616.1 - 0.003 17.9 0.9 0.0034 17.7 0.9 1.3 1 0 0 1 1 1 1 FANCI solenoid 2 Nup54 PF13874.6 EST48616.1 - 0.024 14.7 0.7 0.038 14.1 0.7 1.5 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 SUB1_ProdP9 PF18213.1 EST48616.1 - 0.054 13.3 0.7 0.13 12.1 0.4 1.9 1 1 1 2 2 2 0 SUB1 protease Prodomain ProdP9 Luteo_coat PF00894.18 EST48617.1 - 0.027 14.4 0.0 0.036 13.9 0.0 1.2 1 0 0 1 1 1 0 Luteovirus coat protein Maf1 PF09174.10 EST48618.1 - 7.5e-06 26.2 3.0 1.1e-05 25.7 3.0 1.3 1 0 0 1 1 1 1 Maf1 regulator Ham1p_like PF01725.16 EST48619.1 - 9.8e-06 25.6 0.0 2.4e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Ham1 family Ham1p_like PF01725.16 EST48620.1 - 6.6e-19 68.6 0.0 7.5e-19 68.4 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Flavodoxin_1 PF00258.25 EST48623.1 - 6.2e-14 52.4 0.0 7e-14 52.2 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin Sel1 PF08238.12 EST48623.1 - 0.026 15.2 0.1 2.3 9.0 0.0 2.4 2 0 0 2 2 2 0 Sel1 repeat AAA_35 PF14516.6 EST48623.1 - 0.06 12.2 0.0 0.085 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Flavodoxin_5 PF12724.7 EST48623.1 - 0.09 13.0 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Flavodoxin domain DUF4244 PF14029.6 EST48623.1 - 0.11 12.0 0.2 0.19 11.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4244) PK_C PF02887.16 EST48623.1 - 0.14 12.4 0.0 3.1 8.1 0.0 2.3 1 1 1 2 2 2 0 Pyruvate kinase, alpha/beta domain Trigger_C PF05698.14 EST48624.1 - 0.023 14.7 0.2 0.049 13.6 0.2 1.6 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus Rubrerythrin PF02915.17 EST48625.1 - 5.4e-27 94.9 1.4 6.8e-27 94.5 1.4 1.1 1 0 0 1 1 1 1 Rubrerythrin Ferritin PF00210.24 EST48625.1 - 1.1e-09 38.3 1.4 0.00019 21.4 0.3 2.1 1 1 1 2 2 2 2 Ferritin-like domain Effector_1 PF04518.12 EST48625.1 - 0.029 13.5 0.0 0.04 13.0 0.0 1.1 1 0 0 1 1 1 0 Effector from type III secretion system DUF3039 PF11238.8 EST48625.1 - 0.048 13.4 0.3 0.089 12.6 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3039) zf-UBP PF02148.19 EST48625.1 - 0.085 13.2 0.3 0.18 12.2 0.3 1.5 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Vps36-NZF-N PF16988.5 EST48625.1 - 0.46 9.9 6.3 13 5.2 7.3 2.3 1 1 1 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 EST48625.1 - 1.2 9.3 5.5 3.2 7.9 0.5 2.7 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger ThiF PF00899.21 EST48626.1 - 1e-38 133.1 0.0 1.4e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 EST48626.1 - 0.0029 17.6 0.4 0.095 12.6 0.1 2.4 1 1 1 2 2 2 1 Ubiquitin-activating enzyme active site ANAPC4_WD40 PF12894.7 EST48627.1 - 3.6e-11 43.2 0.7 0.0024 18.1 0.0 5.7 5 1 0 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EST48627.1 - 4.3e-08 33.7 1.2 3.2 8.8 0.2 6.6 7 0 0 7 7 7 2 WD domain, G-beta repeat Sen15 PF09631.10 EST48627.1 - 0.0045 17.3 0.7 3.2 8.1 0.0 3.4 3 0 0 3 3 3 2 Sen15 protein COG5 PF10392.9 EST48627.1 - 0.56 10.4 6.2 0.22 11.7 0.7 3.0 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Luciferase_cat PF10285.9 EST48628.1 - 0.011 15.1 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 0 Luciferase catalytic domain SET PF00856.28 EST48629.1 - 2.1e-18 67.3 0.1 1.5e-17 64.5 0.1 1.9 1 1 0 1 1 1 1 SET domain GAS PF13851.6 EST48630.1 - 0.0053 16.1 21.2 0.0053 16.1 21.2 4.4 1 1 3 4 4 4 1 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 EST48630.1 - 0.0058 15.5 18.1 0.0058 15.5 18.1 5.9 1 1 6 7 7 7 3 Spc7 kinetochore protein Pox_A_type_inc PF04508.12 EST48630.1 - 0.0082 16.0 12.6 3.4 7.7 0.8 6.4 6 0 0 6 6 6 2 Viral A-type inclusion protein repeat DUF630 PF04783.12 EST48630.1 - 0.021 15.0 0.2 0.056 13.6 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF630) RNA_pol_Rpb1_5 PF04998.17 EST48632.1 - 4.4e-62 209.9 0.1 8.7e-62 209.0 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EST48632.1 - 1.8e-58 197.4 0.1 9.3e-58 195.1 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EST48632.1 - 3.3e-41 140.8 0.2 3.6e-40 137.4 0.1 2.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 EST48632.1 - 6.5e-27 94.7 8.2 5.5e-26 91.6 3.6 2.8 2 0 0 2 2 2 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 EST48632.1 - 6.5e-24 84.0 0.5 3.9e-23 81.5 0.5 2.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_6 PF04992.14 EST48632.1 - 2.7e-14 53.4 13.8 4.1e-11 43.1 8.9 2.8 1 1 0 2 2 2 2 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 EST48632.1 - 0.0013 18.7 1.0 0.0049 16.9 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 DUF3659 PF12396.8 EST48633.1 - 0.19 11.7 1.0 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) MORN PF02493.20 EST48633.1 - 0.9 9.6 9.8 37 4.5 0.0 5.5 6 1 0 6 6 6 0 MORN repeat ABC_tran_CTD PF16326.5 EST48635.1 - 0.0015 18.8 10.3 0.0015 18.8 10.3 5.9 3 1 4 7 7 7 1 ABC transporter C-terminal domain HMMR_N PF15905.5 EST48635.1 - 0.0056 16.2 13.4 0.0056 16.2 13.4 3.2 2 1 1 3 3 3 1 Hyaluronan mediated motility receptor N-terminal DUF2443 PF10398.9 EST48635.1 - 0.023 14.8 1.2 0.023 14.8 1.2 4.0 4 2 0 4 4 4 0 Protein of unknown function (DUF2443) Fez1 PF06818.15 EST48635.1 - 0.05 14.1 41.9 0.18 12.2 14.0 2.7 1 1 1 2 2 2 0 Fez1 bZIP_1 PF00170.21 EST48635.1 - 0.2 11.8 21.4 5.1 7.3 2.7 4.9 3 2 1 4 4 4 0 bZIP transcription factor HAP1_N PF04849.13 EST48635.1 - 2.5 7.2 49.2 0.042 13.1 37.5 2.4 1 1 1 2 2 2 0 HAP1 N-terminal conserved region GAS PF13851.6 EST48635.1 - 2.9 7.2 49.2 0.1 11.9 14.6 2.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding EF-hand_7 PF13499.6 EST48636.1 - 2.5e-12 47.1 2.9 1.4e-07 31.9 0.2 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EST48636.1 - 1.1e-11 43.7 0.4 3.4e-05 23.4 0.1 3.3 2 1 1 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 EST48636.1 - 1.1e-10 40.3 1.0 6.9e-05 22.1 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 EST48636.1 - 1.9e-07 30.2 4.4 6.9e-06 25.3 0.1 3.1 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 EST48636.1 - 1.9e-05 24.4 0.7 0.0058 16.4 0.0 3.2 3 1 1 4 4 4 1 EF-hand domain pair EF-hand_9 PF14658.6 EST48636.1 - 0.0021 18.3 0.0 0.18 12.2 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain DUF2666 PF10869.8 EST48636.1 - 0.017 15.3 0.0 0.46 10.7 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) TerB PF05099.13 EST48636.1 - 0.065 13.2 0.0 0.54 10.2 0.0 2.0 2 0 0 2 2 2 0 Tellurite resistance protein TerB MA3 PF02847.17 EST48636.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 MA3 domain Laminin_I PF06008.14 EST48638.1 - 0.0059 16.3 1.2 0.0059 16.3 1.2 1.6 2 0 0 2 2 2 1 Laminin Domain I SpoOE-like PF09388.10 EST48638.1 - 0.016 15.1 1.2 0.11 12.4 0.5 2.5 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein DASH_Dad3 PF08656.10 EST48638.1 - 0.92 9.6 7.5 4.9 7.3 0.7 3.2 3 1 0 3 3 3 0 DASH complex subunit Dad3 FlxA PF14282.6 EST48638.1 - 5.9 7.0 9.6 0.75 9.8 4.9 1.9 2 0 0 2 2 2 0 FlxA-like protein SAC3_GANP PF03399.16 EST48639.1 - 0.0036 16.7 0.1 0.0051 16.2 0.1 1.2 1 0 0 1 1 1 1 SAC3/GANP family Peptidase_M24 PF00557.24 EST48640.1 - 6.2e-40 137.1 0.2 8.3e-40 136.7 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Lsm_C PF14894.6 EST48640.1 - 0.028 14.2 0.2 0.15 11.9 0.2 2.2 1 0 0 1 1 1 0 Lsm C-terminal Alanine_zipper PF11839.8 EST48642.1 - 0.25 11.7 3.0 11 6.5 0.0 3.4 3 0 0 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein REF PF05755.12 EST48642.1 - 2.5 7.9 10.1 6.8 6.4 2.1 3.3 2 1 1 3 3 3 0 Rubber elongation factor protein (REF) Tup_N PF08581.10 EST48642.1 - 3.6 7.9 26.1 0.37 11.1 4.2 5.3 3 2 2 5 5 5 0 Tup N-terminal Hydrolase PF00702.26 EST48643.1 - 5.3e-06 26.9 0.0 0.00028 21.3 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EST48643.1 - 6.5e-05 23.1 0.0 0.00016 21.8 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EST48643.1 - 6.8e-05 22.9 0.0 0.019 15.1 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase HAD PF12710.7 EST48643.1 - 7.1e-05 23.3 0.0 0.0002 21.8 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EST48643.1 - 0.036 14.1 0.0 0.06 13.4 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like Triabin PF03973.13 EST48645.1 - 0.018 15.0 0.2 0.039 13.8 0.2 1.6 1 0 0 1 1 1 0 Triabin EF-hand_1 PF00036.32 EST48646.1 - 4.6e-26 88.4 25.4 8.9e-07 28.0 0.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EST48646.1 - 1.8e-25 89.2 13.5 1.2e-12 48.0 1.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EST48646.1 - 3.3e-24 82.7 18.5 3.2e-07 29.7 0.1 4.1 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EST48646.1 - 1.8e-18 66.1 21.0 8.8e-13 47.9 3.2 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EST48646.1 - 4.6e-18 63.8 20.4 3.8e-06 26.1 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EST48646.1 - 9.1e-09 35.5 1.5 0.00017 21.9 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EST48646.1 - 1.8e-06 27.8 8.3 0.0023 17.8 0.1 3.1 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EST48646.1 - 6.4e-06 26.5 2.6 0.0095 16.3 0.5 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region p25-alpha PF05517.12 EST48646.1 - 0.037 14.2 3.8 0.34 11.0 0.2 2.3 1 1 1 2 2 2 0 p25-alpha PNPase PF03726.14 EST48646.1 - 0.041 14.4 1.3 0.54 10.8 0.1 2.5 2 1 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain DUF3349 PF11829.8 EST48646.1 - 0.091 13.6 0.1 0.52 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) EF-hand_7 PF13499.6 EST48647.1 - 6.5e-25 87.4 12.1 1.9e-13 50.7 2.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EST48647.1 - 5.4e-24 81.9 20.3 1.4e-06 27.4 0.4 4.1 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EST48647.1 - 3.1e-21 73.4 14.5 2.7e-06 26.9 0.2 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EST48647.1 - 1.8e-19 69.3 19.7 7.3e-11 41.8 1.8 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EST48647.1 - 1.4e-14 52.8 15.5 6.6e-05 22.2 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EST48647.1 - 3.3e-06 27.3 1.0 0.0046 17.2 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EST48647.1 - 5.6e-06 26.2 9.2 0.00025 21.0 0.7 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EST48647.1 - 0.0091 16.3 4.3 0.2 12.0 0.2 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 EST48647.1 - 0.41 10.5 7.0 22 5.0 0.1 4.0 3 1 1 4 4 4 0 EF hand Flavodoxin_1 PF00258.25 EST48648.1 - 1.1e-22 80.8 0.0 1.4e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 EST48648.1 - 8.2e-07 29.4 0.0 1.2e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_NdrI PF07972.11 EST48648.1 - 0.0084 16.3 0.1 0.013 15.7 0.1 1.2 1 0 0 1 1 1 1 NrdI Flavodoxin like Flavodoxin_3 PF12641.7 EST48648.1 - 0.019 14.7 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin domain Rubrerythrin PF02915.17 EST48649.1 - 3.1e-27 95.6 1.7 3.9e-27 95.3 1.7 1.1 1 0 0 1 1 1 1 Rubrerythrin Ferritin PF00210.24 EST48649.1 - 1.6e-09 37.9 1.5 0.00027 20.9 0.5 2.1 1 1 1 2 2 2 2 Ferritin-like domain Effector_1 PF04518.12 EST48649.1 - 0.036 13.2 0.0 0.049 12.7 0.0 1.1 1 0 0 1 1 1 0 Effector from type III secretion system DUF3039 PF11238.8 EST48649.1 - 0.047 13.4 0.3 0.089 12.6 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3039) zf-UBP PF02148.19 EST48649.1 - 0.084 13.2 0.3 0.18 12.2 0.3 1.5 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Vps36-NZF-N PF16988.5 EST48649.1 - 0.46 9.9 6.3 13 5.2 7.3 2.3 1 1 1 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 EST48649.1 - 1.2 9.3 5.5 3.2 7.9 0.5 2.8 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger ubiquitin PF00240.23 EST48652.1 - 1.5e-06 27.9 0.3 1.5e-06 27.9 0.3 2.2 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 EST48652.1 - 0.0063 16.3 0.9 0.016 15.0 0.4 2.0 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EST48652.1 - 0.019 15.3 0.6 0.057 13.8 0.6 1.8 1 0 0 1 1 1 0 Ubiquitin-like domain CUE PF02845.16 EST48652.1 - 0.024 14.3 0.6 0.064 13.0 0.0 2.1 2 0 0 2 2 2 0 CUE domain UBA PF00627.31 EST48652.1 - 0.03 14.3 0.7 3.8 7.5 0.0 2.6 2 0 0 2 2 2 0 UBA/TS-N domain YukD PF08817.10 EST48652.1 - 0.032 14.9 0.0 0.23 12.2 0.0 2.2 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD Rubrerythrin PF02915.17 EST48653.1 - 4e-27 95.3 1.7 5.3e-27 94.9 1.7 1.2 1 0 0 1 1 1 1 Rubrerythrin Ferritin PF00210.24 EST48653.1 - 2.6e-09 37.2 1.7 0.00037 20.5 0.7 2.1 1 1 1 2 2 2 2 Ferritin-like domain Effector_1 PF04518.12 EST48653.1 - 0.032 13.3 0.0 0.044 12.9 0.0 1.1 1 0 0 1 1 1 0 Effector from type III secretion system DUF3039 PF11238.8 EST48653.1 - 0.057 13.2 0.3 0.11 12.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3039) zf-UBP PF02148.19 EST48653.1 - 0.1 13.0 0.3 0.22 11.9 0.3 1.5 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Vps36-NZF-N PF16988.5 EST48653.1 - 0.61 9.5 6.2 14 5.1 7.2 2.2 1 1 1 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 EST48653.1 - 2.5 8.2 6.2 3.7 7.7 0.6 2.7 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger Kelch_4 PF13418.6 EST48655.1 - 0.00023 21.1 4.1 0.00063 19.7 0.0 3.5 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.15 EST48655.1 - 0.15 12.1 1.4 1.9 8.6 0.0 3.2 3 1 0 3 3 3 0 Kelch motif LPP PF04728.13 EST48656.1 - 0.0077 16.6 0.4 0.0077 16.6 0.4 10.7 10 4 3 13 13 13 1 Lipoprotein leucine-zipper CENP-F_leu_zip PF10473.9 EST48656.1 - 0.0085 16.1 17.9 0.0085 16.1 17.9 8.1 2 2 7 9 9 9 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tma16 PF11176.8 EST48657.1 - 9.6e-13 48.2 3.1 3.6e-12 46.4 3.1 1.7 1 1 0 1 1 1 1 Translation machinery-associated protein 16 dUTPase_2 PF08761.11 EST48657.1 - 0.008 16.4 0.4 0.0099 16.1 0.4 1.1 1 0 0 1 1 1 1 dUTPase ARID PF01388.21 EST48662.1 - 1.7e-15 57.5 0.1 4e-15 56.2 0.1 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain NTase_sub_bind PF08780.11 EST48662.1 - 0.019 14.9 0.7 0.045 13.7 0.0 2.0 2 1 0 2 2 2 0 Nucleotidyltransferase substrate binding protein like Pox_J1 PF03338.15 EST48662.1 - 0.12 12.2 0.6 5.8 6.8 0.1 2.2 2 0 0 2 2 2 0 Poxvirus J1 protein CBFD_NFYB_HMF PF00808.23 EST48663.1 - 1.1e-10 41.6 0.5 1.3e-10 41.4 0.5 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EST48663.1 - 1.9e-05 25.0 0.3 2.3e-05 24.8 0.3 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 BBS1 PF14779.6 EST48664.1 - 9.7e-13 48.1 0.3 2.4e-12 46.9 0.3 1.6 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 1 LRR_5 PF13306.6 EST48664.1 - 0.066 13.2 9.1 0.86 9.6 0.5 2.7 2 1 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) CNH PF00780.22 EST48665.1 - 0.0023 17.6 1.2 0.014 15.0 0.1 2.3 1 1 0 2 2 2 1 CNH domain BBS2_Mid PF14783.6 EST48665.1 - 0.023 14.7 0.1 1.3 9.1 0.1 2.4 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region ATR13 PF16829.5 EST48666.1 - 0.066 13.6 0.2 0.51 10.7 0.2 2.6 1 0 0 1 1 1 0 Avirulence protein ATR13, RxLR effector TAFII28 PF04719.14 EST48666.1 - 0.67 10.1 4.1 1.4 9.1 0.4 3.2 2 0 0 2 2 2 0 hTAFII28-like protein conserved region DUF2205 PF10224.9 EST48667.1 - 0.1 12.6 2.1 0.84 9.7 0.6 2.5 2 0 0 2 2 2 0 Short coiled-coil protein Cut8 PF08559.10 EST48668.1 - 0.034 13.8 0.3 0.047 13.3 0.2 1.4 1 1 0 1 1 1 0 Cut8, nuclear proteasome tether protein Ribosomal_S19 PF00203.21 EST48669.1 - 1.9e-29 101.4 0.3 2.5e-29 101.0 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 GlcNAc-1_reg PF18440.1 EST48671.1 - 0.0048 17.1 0.6 0.058 13.6 0.5 3.0 2 0 0 2 2 2 1 Putative GlcNAc-1 phosphotransferase regulatory domain Rtt106 PF08512.12 EST48671.1 - 0.047 14.1 2.4 0.6 10.6 0.2 3.1 2 0 0 2 2 2 0 Histone chaperone Rttp106-like Myb_DNA-binding PF00249.31 EST48672.1 - 5.9e-10 39.2 0.2 9.5e-10 38.5 0.2 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST48672.1 - 0.00028 21.1 0.0 0.00032 20.9 0.0 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST48672.1 - 0.0028 17.5 0.0 0.003 17.4 0.0 1.2 1 0 0 1 1 1 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EST48672.1 - 0.0033 17.6 0.1 0.0048 17.1 0.1 1.3 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Peptidase_S9 PF00326.21 EST48672.1 - 0.077 12.5 0.0 0.087 12.3 0.0 1.0 1 0 0 1 1 1 0 Prolyl oligopeptidase family PTCRA PF15028.6 EST48672.1 - 0.12 12.0 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Pre-T-cell antigen receptor TMEM131_like PF12371.8 EST48674.1 - 1.2 9.4 13.2 7.4 6.9 0.0 5.7 5 0 0 5 5 5 0 Transmembrane protein 131-like DUF2023 PF09633.10 EST48675.1 - 0.13 12.4 1.0 0.67 10.1 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2023) Pepdidase_M14_N PF18027.1 EST48676.1 - 0.021 15.2 0.0 0.11 12.8 0.0 2.3 1 0 0 1 1 1 0 Cytosolic carboxypeptidase N-terminal domain Peptidase_M14 PF00246.24 EST48676.1 - 0.025 14.4 0.0 0.057 13.2 0.0 1.6 1 0 0 1 1 1 0 Zinc carboxypeptidase DUF2405 PF10293.9 EST48676.1 - 0.028 14.4 1.1 0.07 13.1 1.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2405) DUF4826 PF16108.5 EST48676.1 - 0.069 13.4 0.1 0.23 11.7 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4826) PRK PF00485.18 EST48677.1 - 3.7e-13 49.7 0.1 2.4e-12 47.0 0.1 2.3 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 EST48677.1 - 0.0021 18.2 0.0 0.013 15.7 0.0 2.2 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 EST48677.1 - 0.0084 15.9 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EST48677.1 - 0.01 15.1 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin APS_kinase PF01583.20 EST48677.1 - 0.01 15.7 0.0 0.028 14.3 0.0 1.6 2 0 0 2 2 2 0 Adenylylsulphate kinase KTI12 PF08433.10 EST48677.1 - 0.014 14.9 0.7 0.048 13.1 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 SRP54 PF00448.22 EST48677.1 - 0.038 13.6 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_18 PF13238.6 EST48677.1 - 0.056 14.0 0.0 0.18 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain Chordopox_A20R PF05941.13 EST48677.1 - 0.063 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Chordopoxvirus A20R protein AAA_14 PF13173.6 EST48677.1 - 0.087 12.9 0.0 0.32 11.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EST48677.1 - 0.17 11.9 0.0 0.45 10.5 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EST48677.1 - 0.19 12.0 0.0 0.36 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Myb_DNA-binding PF00249.31 EST48679.1 - 3.8e-09 36.6 0.2 6e-09 36.0 0.2 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST48679.1 - 0.0017 18.6 0.0 0.0029 17.8 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EST48679.1 - 0.012 15.8 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 EST48679.1 - 0.014 15.3 0.1 0.023 14.6 0.1 1.3 1 0 0 1 1 1 0 Myb DNA-binding like Myb_DNA-binding PF00249.31 EST48680.1 - 6.2e-10 39.1 0.2 9.5e-10 38.5 0.2 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST48680.1 - 0.0003 21.0 0.0 0.00038 20.6 0.0 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST48680.1 - 0.003 17.4 0.1 0.0034 17.2 0.1 1.2 1 0 0 1 1 1 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EST48680.1 - 0.0033 17.6 0.1 0.0048 17.1 0.1 1.3 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DUF3545 PF12065.8 EST48681.1 - 0.14 12.2 7.5 0.047 13.7 2.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3545) Pkinase PF00069.25 EST48682.1 - 7.6e-23 81.2 0.7 1e-22 80.8 0.7 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST48682.1 - 1.4e-16 60.6 0.1 2.6e-16 59.7 0.1 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase DUF4719 PF15843.5 EST48683.1 - 0.67 10.0 1.4 0.69 10.0 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) SLATT_6 PF18169.1 EST48684.1 - 0.2 11.2 3.7 0.13 11.9 2.1 1.4 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 PI3_PI4_kinase PF00454.27 EST48685.1 - 7.2e-30 104.6 0.1 4e-21 75.9 0.1 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EST48685.1 - 3.2e-09 36.4 1.1 9.4e-09 34.9 1.1 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4840 PF16128.5 EST48685.1 - 0.036 14.1 0.2 0.1 12.7 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4840) MinE PF03776.14 EST48687.1 - 0.027 14.5 6.0 0.71 9.9 0.3 2.9 2 0 0 2 2 2 0 Septum formation topological specificity factor MinE BBS2_N PF14781.6 EST48689.1 - 0.36 10.7 4.8 1.1 9.2 2.9 2.6 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal Ank_2 PF12796.7 EST48691.1 - 9.3e-07 29.3 0.0 0.0066 17.0 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EST48691.1 - 1e-06 29.1 0.0 0.54 10.9 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EST48691.1 - 0.0067 16.8 0.2 12 6.9 0.0 4.4 5 0 0 5 5 5 1 Ankyrin repeat DBB PF14545.6 EST48691.1 - 0.062 13.2 1.0 0.17 11.8 0.3 2.0 2 0 0 2 2 2 0 Dof, BCAP, and BANK (DBB) motif, DndE PF08870.11 EST48692.1 - 0.035 14.4 0.1 0.078 13.2 0.1 1.5 1 0 0 1 1 1 0 DNA sulphur modification protein DndE AAA PF00004.29 EST48693.1 - 0.00018 22.0 4.0 0.021 15.2 0.7 2.8 1 1 1 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EST48693.1 - 0.0013 19.0 6.4 0.097 12.9 0.1 3.4 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.6 EST48693.1 - 0.004 17.6 0.0 0.076 13.4 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain TniB PF05621.11 EST48693.1 - 0.012 15.0 0.7 0.34 10.3 0.1 2.7 3 0 0 3 3 3 0 Bacterial TniB protein RNA_helicase PF00910.22 EST48693.1 - 0.024 15.0 0.3 0.22 11.9 0.0 2.5 2 0 0 2 2 2 0 RNA helicase DEAD PF00270.29 EST48693.1 - 0.11 12.2 1.5 0.59 9.9 0.1 2.7 1 1 2 3 3 3 0 DEAD/DEAH box helicase MFS_1 PF07690.16 EST48695.1 - 4e-27 95.1 20.0 9.7e-23 80.6 8.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATPase_gene1 PF09527.10 EST48695.1 - 0.32 11.2 13.3 0.11 12.7 1.0 3.2 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Spore_YhaL PF14147.6 EST48695.1 - 6.8 6.5 5.7 9.8 6.0 2.5 2.8 2 0 0 2 2 2 0 Sporulation protein YhaL Mitovir_RNA_pol PF05919.11 EST48696.1 - 0.58 9.3 6.8 0.82 8.8 6.8 1.1 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase Myb_DNA-bind_5 PF13873.6 EST48696.1 - 0.84 9.8 8.0 1.6 8.9 0.1 3.6 4 1 0 4 4 4 0 Myb/SANT-like DNA-binding domain Baculo_PEP_C PF04513.12 EST48696.1 - 0.93 9.5 7.8 0.86 9.6 1.6 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spore_III_AB PF09548.10 EST48696.1 - 2.5 8.2 13.6 0.13 12.3 6.8 2.1 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) NPV_P10 PF05531.12 EST48696.1 - 6.3 7.3 7.7 4.3 7.9 1.2 3.0 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein HSCB_C PF07743.13 EST48696.1 - 7.7 7.1 16.4 3.1 8.4 1.7 3.8 1 1 3 4 4 4 0 HSCB C-terminal oligomerisation domain ATP-synt_ab PF00006.25 EST48697.1 - 1.5e-93 312.3 0.0 2.7e-93 311.5 0.0 1.4 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 EST48697.1 - 1.2e-27 96.2 0.0 2.7e-27 95.0 0.0 1.7 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 EST48697.1 - 1.7e-12 47.7 1.0 5.6e-12 46.0 0.5 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain Peptidase_M23 PF01551.22 EST48697.1 - 0.0037 17.4 0.1 1.3 9.2 0.0 3.3 3 0 0 3 3 3 1 Peptidase family M23 Rep_Org_C PF06926.11 EST48699.1 - 0.0088 16.3 4.6 0.014 15.7 1.5 3.0 2 0 0 2 2 2 1 Putative replisome organiser protein C-terminus Helicase_C PF00271.31 EST48700.1 - 2e-16 60.3 0.4 7.5e-15 55.2 0.0 3.2 3 1 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 EST48700.1 - 2e-12 47.2 0.3 2.7e-11 43.6 0.2 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 EST48700.1 - 0.0018 19.0 0.8 0.0055 17.4 0.8 1.8 1 0 0 1 1 1 1 RecQ zinc-binding Ribosomal_L20 PF00453.18 EST48702.1 - 0.088 12.9 0.7 9 6.4 0.2 2.4 1 1 0 2 2 2 0 Ribosomal protein L20 zf-CHY PF05495.12 EST48703.1 - 1e-12 48.3 14.7 1.5e-12 47.8 14.7 1.3 1 0 0 1 1 1 1 CHY zinc finger Acatn PF13000.7 EST48704.1 - 0.63 8.5 1.4 0.85 8.0 1.4 1.1 1 0 0 1 1 1 0 Acetyl-coenzyme A transporter 1 RabGAP-TBC PF00566.18 EST48708.1 - 3.7e-05 23.5 3.3 5.5e-05 22.9 3.3 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CagS PF16707.5 EST48708.1 - 0.065 13.2 0.2 0.16 11.9 0.1 1.7 2 0 0 2 2 2 0 Cag pathogenicity island protein S of Helicobacter pylori Asparaginase PF00710.20 EST48710.1 - 4e-57 192.8 0.0 6.1e-57 192.3 0.0 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 EST48710.1 - 9.9e-20 70.9 0.0 1.6e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain AMP-binding PF00501.28 EST48710.1 - 0.052 12.1 0.1 0.091 11.3 0.1 1.3 1 0 0 1 1 1 0 AMP-binding enzyme Asparaginase PF00710.20 EST48711.1 - 2.8e-57 193.4 0.0 3.9e-57 192.9 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 EST48711.1 - 7.4e-20 71.3 0.0 1.2e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain RabGAP-TBC PF00566.18 EST48713.1 - 3.1e-05 23.8 3.4 4.3e-05 23.3 3.4 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CagS PF16707.5 EST48713.1 - 0.064 13.3 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Cag pathogenicity island protein S of Helicobacter pylori Auto_anti-p27 PF06677.12 EST48716.1 - 8e-11 41.9 12.4 5.9e-08 32.7 2.4 2.2 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) IBR PF01485.21 EST48716.1 - 0.0022 18.2 8.7 0.19 12.0 1.1 2.3 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain zf-ribbon_3 PF13248.6 EST48716.1 - 0.025 14.0 5.9 0.81 9.2 0.2 3.5 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_15 PF17032.5 EST48716.1 - 0.038 14.7 2.5 0.61 10.9 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon family DZR PF12773.7 EST48716.1 - 0.046 13.8 7.5 0.64 10.1 7.4 2.4 1 1 0 1 1 1 0 Double zinc ribbon Zn_ribbon_SprT PF17283.2 EST48716.1 - 0.048 13.6 0.1 0.048 13.6 0.1 2.0 2 0 0 2 2 2 0 SprT-like zinc ribbon domain BppU_N PF10651.9 EST48716.1 - 0.049 13.3 1.5 0.064 13.0 1.5 1.2 1 0 0 1 1 1 0 BppU N-terminal domain OrfB_Zn_ribbon PF07282.11 EST48716.1 - 0.057 13.3 1.4 2.7 8.0 0.1 2.3 2 0 0 2 2 2 0 Putative transposase DNA-binding domain YacG PF03884.14 EST48716.1 - 0.058 13.1 3.1 2.3 8.0 0.5 2.7 1 1 1 2 2 2 0 DNA gyrase inhibitor YacG TF_Zn_Ribbon PF08271.12 EST48716.1 - 0.53 9.8 9.2 6.8 6.3 0.3 2.9 2 1 0 2 2 2 0 TFIIB zinc-binding zinc-ribbons_6 PF07191.12 EST48716.1 - 0.65 10.0 7.0 7.7 6.6 7.3 2.2 1 1 1 2 2 2 0 zinc-ribbons C1_1 PF00130.22 EST48716.1 - 0.74 9.7 3.2 1.2 9.1 0.3 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 EST48716.1 - 0.82 9.6 6.7 1 9.4 1.4 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Zn_Tnp_IS1595 PF12760.7 EST48716.1 - 1.5 8.9 4.8 24 5.0 0.2 3.2 3 0 0 3 3 3 0 Transposase zinc-ribbon domain DNA_ligase_ZBD PF03119.16 EST48716.1 - 1.7 8.7 9.4 8 6.6 1.8 3.8 3 1 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain PGK PF00162.19 EST48717.1 - 9.2e-137 456.0 0.2 1e-136 455.8 0.2 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Thioredoxin PF00085.20 EST48719.1 - 1e-16 60.8 0.0 1.1e-16 60.7 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EST48719.1 - 5.9e-05 23.5 0.0 8.7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EST48719.1 - 0.018 15.4 0.1 0.33 11.3 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_5 PF13743.6 EST48719.1 - 0.085 12.5 0.0 1.1 8.9 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin UPRTase PF14681.6 EST48720.1 - 1e-61 208.0 0.0 1.2e-61 207.8 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EST48720.1 - 8.2e-14 51.4 0.1 1.4e-13 50.6 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain SYCP2_SLD PF18584.1 EST48721.1 - 0.044 14.0 1.8 0.073 13.3 1.8 1.3 1 0 0 1 1 1 0 Synaptonemal complex 2 Spt16M-like domain Cas9_PI2 PF18070.1 EST48721.1 - 0.13 13.0 0.6 0.28 11.9 0.6 1.6 1 0 0 1 1 1 0 CRISPR-Cas9 PI domain BLOC1S3 PF15753.5 EST48722.1 - 0.066 13.3 4.0 0.22 11.7 4.0 2.1 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 zf-UBR PF02207.20 EST48724.1 - 1.3e-08 34.9 16.2 1.3e-08 34.9 16.2 3.1 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) Pkinase PF00069.25 EST48725.1 - 4.1e-66 223.0 0.1 5.5e-66 222.6 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST48725.1 - 3.8e-42 144.4 0.1 4.9e-42 144.0 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EST48725.1 - 0.0022 17.3 0.5 0.033 13.5 0.0 2.1 1 1 0 2 2 2 1 Kinase-like Abi_2 PF07751.11 EST48725.1 - 0.0025 18.1 0.7 0.0051 17.1 0.7 1.4 1 0 0 1 1 1 1 Abi-like protein DUF3310 PF11753.8 EST48725.1 - 0.027 14.7 0.3 10 6.4 0.0 2.7 2 1 0 2 2 2 0 Protein of unknwon function (DUF3310) Vac_Fusion PF02346.16 EST48728.1 - 0.065 12.9 0.1 0.19 11.4 0.0 1.7 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 GDPD PF03009.17 EST48729.1 - 6.8e-06 26.0 0.1 1.1e-05 25.3 0.1 1.5 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF5539 PF17693.1 EST48730.1 - 0.15 11.7 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5539) PT PF04886.12 EST48731.1 - 8.4e-08 31.6 63.3 1.1e+03 -0.7 0.2 7.9 3 1 0 3 3 1 0 PT repeat Trigger_C PF05698.14 EST48731.1 - 2.1e-05 24.6 22.7 0.057 13.4 10.6 2.8 1 1 1 2 2 2 2 Bacterial trigger factor protein (TF) C-terminus GlutR_dimer PF00745.20 EST48731.1 - 8.3e-05 23.0 28.0 1.3e+04 -3.3 0.2 6.0 2 1 0 2 2 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF445 PF04286.12 EST48731.1 - 0.00025 21.0 14.1 0.00025 21.0 14.1 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF445) YueH PF14166.6 EST48731.1 - 0.00052 19.8 23.7 1.8e+04 -10.2 23.7 4.6 1 1 0 1 1 0 0 YueH-like protein MgtE_N PF03448.17 EST48731.1 - 0.00089 19.8 6.9 0.78 10.4 6.9 2.6 1 1 0 1 1 1 1 MgtE intracellular N domain DUF2939 PF11159.8 EST48731.1 - 0.0011 19.3 22.3 3.4e+03 -1.5 0.0 4.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2939) YpjP PF14005.6 EST48731.1 - 0.003 17.6 3.3 1 9.4 3.3 2.5 1 1 0 1 1 1 1 YpjP-like protein MetOD1 PF18546.1 EST48731.1 - 0.093 12.7 13.7 2.9e+02 1.4 13.7 3.0 1 1 0 1 1 1 0 Metanogen output domain 1 pP_pnuc_2 PF18166.1 EST48731.1 - 0.17 12.0 8.1 1.3e+03 -0.6 8.1 3.9 1 1 0 1 1 1 0 Predicted pPIWI-associating nuclease LBP_BPI_CETP PF01273.25 EST48731.1 - 0.18 11.4 33.9 5.8e+03 -3.3 0.0 5.2 2 1 0 2 2 1 0 LBP / BPI / CETP family, N-terminal domain HI0933_like PF03486.14 EST48731.1 - 0.42 9.3 28.6 1.9 7.1 12.0 2.2 1 1 1 2 2 2 0 HI0933-like protein Cystatin PF00031.21 EST48732.1 - 4.4e-07 30.1 0.1 4.8e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 Cystatin domain SQAPI PF16845.5 EST48732.1 - 2.6e-05 24.5 0.1 3.4e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Aspartic acid proteinase inhibitor DctP PF03480.13 EST48732.1 - 0.053 12.8 0.0 0.063 12.6 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 DUF5607 PF18355.1 EST48732.1 - 0.12 12.9 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5607) KLRAQ PF10205.9 EST48733.1 - 0.0067 16.6 1.8 0.0067 16.6 1.8 2.6 1 1 0 2 2 2 1 Predicted coiled-coil domain-containing protein PA28_alpha PF02251.18 EST48733.1 - 0.037 14.1 0.7 0.67 10.0 0.0 2.9 3 0 0 3 3 3 0 Proteasome activator pa28 alpha subunit ZapB PF06005.12 EST48733.1 - 0.8 10.2 11.6 86 3.7 11.7 3.3 1 1 0 1 1 1 0 Cell division protein ZapB EamA PF00892.20 EST48735.1 - 1.2e-07 31.9 1.8 1.2e-07 31.9 1.8 4.5 3 2 1 4 4 4 1 EamA-like transporter family Nuc_sug_transp PF04142.15 EST48735.1 - 8.9e-05 21.8 2.3 8.9e-05 21.8 2.3 2.1 2 0 0 2 2 2 1 Nucleotide-sugar transporter PUNUT PF16913.5 EST48735.1 - 0.00048 19.4 17.6 0.0016 17.7 17.6 1.9 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport CPP1-like PF11833.8 EST48735.1 - 0.0014 18.3 1.5 0.0034 17.1 1.4 1.7 1 1 0 1 1 1 1 Protein CHAPERONE-LIKE PROTEIN OF POR1-like RhodobacterPufX PF11511.8 EST48735.1 - 0.015 14.9 0.7 0.53 9.9 0.0 2.8 2 0 0 2 2 2 0 Intrinsic membrane protein PufX CRT-like PF08627.10 EST48735.1 - 0.019 13.9 17.1 0.014 14.3 9.7 2.1 1 1 1 2 2 2 0 CRT-like, chloroquine-resistance transporter-like CAF1C_H4-bd PF12265.8 EST48736.1 - 2.5e-09 37.3 0.3 5.8e-09 36.1 0.3 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EST48736.1 - 0.0001 23.0 4.7 1 10.4 0.0 5.7 6 0 0 6 6 6 2 WD domain, G-beta repeat GDPD PF03009.17 EST48740.1 - 6.5e-07 29.3 0.2 1.2e-06 28.5 0.2 1.5 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF1410 PF07198.11 EST48740.1 - 0.13 12.8 0.2 1.5 9.3 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1410) ROK PF00480.20 EST48742.1 - 4.5e-71 239.7 3.3 5.2e-71 239.5 3.3 1.0 1 0 0 1 1 1 1 ROK family FGGY_N PF00370.21 EST48742.1 - 6.9e-05 22.5 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 EST48742.1 - 0.0058 16.2 0.0 0.33 10.4 0.0 2.2 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family Hydant_A_N PF05378.13 EST48742.1 - 0.02 14.6 0.3 0.04 13.6 0.3 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region Myb_DNA-binding PF00249.31 EST48746.1 - 3.4e-13 49.5 0.4 1e-05 25.6 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST48746.1 - 3.4e-12 46.4 3.3 2.2e-11 43.9 1.1 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EST48746.1 - 0.0027 18.1 1.8 0.58 10.6 0.4 2.3 2 0 0 2 2 2 2 Myb/SANT-like DNA-binding domain SLIDE PF09111.10 EST48746.1 - 0.013 15.5 0.3 0.1 12.6 0.0 2.1 1 1 1 2 2 2 0 SLIDE VanZ PF04892.12 EST48748.1 - 0.019 15.7 0.3 0.023 15.4 0.3 1.1 1 0 0 1 1 1 0 VanZ like family ParcG PF10274.9 EST48749.1 - 7.8e-79 264.1 0.0 9.8e-79 263.7 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein DCB PF16213.5 EST48749.1 - 0.046 13.4 0.0 0.086 12.5 0.0 1.4 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 ToxN_toxin PF13958.6 EST48749.1 - 0.082 13.2 0.3 0.32 11.2 0.0 1.9 2 0 0 2 2 2 0 Toxin ToxN, type III toxin-antitoxin system MMS19_C PF12460.8 EST48749.1 - 0.085 12.0 0.0 0.097 11.8 0.0 1.2 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal DUF2073 PF09846.9 EST48750.1 - 0.065 13.1 0.1 0.068 13.0 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2073) Acyltransferase PF01553.21 EST48751.1 - 2.8e-10 39.9 0.0 5e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase SHIPPO-rpt PF07004.12 EST48752.1 - 0.021 15.7 7.0 13 6.9 0.1 5.0 5 1 0 5 5 5 0 Sperm-tail PG-rich repeat EF-hand_7 PF13499.6 EST48754.1 - 1.2e-30 105.7 2.6 3.8e-15 56.1 1.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EST48754.1 - 7.6e-30 100.2 4.8 1e-08 34.1 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EST48754.1 - 6.2e-24 81.8 4.4 6.9e-08 31.8 0.5 4.5 3 1 1 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 EST48754.1 - 9.1e-24 83.1 9.0 5.3e-10 39.0 0.1 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EST48754.1 - 1.4e-18 65.4 6.0 1.9e-06 27.1 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 EST48754.1 - 9e-13 48.4 0.0 1.2e-05 25.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 EST48754.1 - 1.4e-06 28.3 5.6 0.0056 16.8 0.2 3.0 1 1 3 4 4 4 4 Dockerin type I domain SPARC_Ca_bdg PF10591.9 EST48754.1 - 2.9e-06 27.6 0.0 0.067 13.5 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EST48754.1 - 4.1e-06 26.7 0.3 0.056 13.4 0.2 2.1 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF5580 PF17743.1 EST48754.1 - 0.00047 18.8 0.0 0.0005 18.8 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) EFhand_Ca_insen PF08726.10 EST48754.1 - 0.0036 17.4 0.1 0.012 15.7 0.0 2.0 2 1 0 2 2 2 1 Ca2+ insensitive EF hand Caleosin PF05042.13 EST48754.1 - 0.005 16.8 0.1 0.75 9.7 0.0 2.6 2 2 1 3 3 3 1 Caleosin related protein EF-hand_11 PF08976.11 EST48754.1 - 0.0066 17.3 0.1 0.036 14.9 0.0 1.8 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 EST48754.1 - 0.03 14.4 0.0 0.17 11.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) LydB PF16084.5 EST48755.1 - 0.13 12.1 0.0 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 LydA-holin antagonist tRNA-synt_1c PF00749.21 EST48756.1 - 3.5e-96 321.8 0.0 4.7e-96 321.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EST48756.1 - 3.6e-21 75.8 1.1 7.6e-21 74.7 0.2 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain Plasmod_dom_1 PF09715.10 EST48758.1 - 0.33 11.0 2.1 1.4 9.1 0.1 2.6 3 0 0 3 3 3 0 Plasmodium protein of unknown function (Plasmod_dom_1) Sec7 PF01369.20 EST48759.1 - 4.4e-32 111.2 0.2 7.7e-31 107.2 0.2 3.1 1 1 0 1 1 1 1 Sec7 domain Pentapeptide_4 PF13599.6 EST48760.1 - 1.8 8.8 16.4 0.2 11.9 3.5 4.0 2 1 1 3 3 3 0 Pentapeptide repeats (9 copies) DUF1254 PF06863.12 EST48761.1 - 0.047 13.7 0.0 1.3 9.1 0.0 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1254) CCSMST1 PF15013.6 EST48761.1 - 0.11 12.6 0.0 0.11 12.6 0.0 1.8 2 0 0 2 2 2 0 CCSMST1 family GF_recep_IV PF14843.6 EST48761.1 - 1.4 8.7 6.0 7.5 6.4 0.6 2.6 2 0 0 2 2 2 0 Growth factor receptor domain IV Aa_trans PF01490.18 EST48762.1 - 3.3e-46 157.8 39.1 4e-46 157.6 39.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SKG6 PF08693.10 EST48762.1 - 0.15 11.5 0.2 0.15 11.5 0.2 3.1 2 1 0 2 2 2 0 Transmembrane alpha-helix domain MFS_1 PF07690.16 EST48763.1 - 4.1e-23 81.9 47.8 4.9e-23 81.6 41.1 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-C2HC_2 PF13913.6 EST48764.1 - 1.3e-14 53.7 26.2 7.8e-08 32.0 1.6 4.3 4 0 0 4 4 4 3 zinc-finger of a C2HC-type DZR PF12773.7 EST48764.1 - 0.00012 22.0 17.3 0.00014 21.9 1.5 4.9 5 0 0 5 5 5 1 Double zinc ribbon DUF2318 PF10080.9 EST48764.1 - 0.00025 21.1 11.8 0.16 12.1 0.1 3.9 4 0 0 4 4 4 3 Predicted membrane protein (DUF2318) zinc_ribbon_2 PF13240.6 EST48764.1 - 0.0028 17.3 6.6 0.0028 17.3 6.6 5.9 5 1 1 6 6 6 2 zinc-ribbon domain FAM76 PF16046.5 EST48764.1 - 0.083 12.2 2.2 4.3 6.6 0.0 3.0 3 0 0 3 3 3 0 FAM76 protein Actin_micro PF17003.5 EST48764.1 - 0.28 10.3 0.1 1.8 7.7 0.0 2.1 2 0 0 2 2 2 0 Putative actin-like family zf_UBZ PF18439.1 EST48764.1 - 0.32 10.6 14.9 2.5 7.8 0.0 5.1 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger Trm112p PF03966.16 EST48764.1 - 1.4 9.6 3.4 2.5e+02 2.3 0.0 4.1 4 0 0 4 4 4 0 Trm112p-like protein Cript PF10235.9 EST48764.1 - 2.2 8.9 7.1 14 6.3 0.1 4.1 4 0 0 4 4 4 0 Microtubule-associated protein CRIPT DHHC PF01529.20 EST48766.1 - 1.4e-14 54.3 12.4 1.4e-14 54.3 12.4 2.9 2 2 0 2 2 2 1 DHHC palmitoyltransferase Ribosomal_S7e PF01251.18 EST48768.1 - 2e-22 79.8 1.3 2.7e-22 79.4 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S7e XhlA PF10779.9 EST48769.1 - 4.5 7.5 8.8 11 6.3 3.3 2.9 2 0 0 2 2 2 0 Haemolysin XhlA UPF0004 PF00919.20 EST48770.1 - 0.041 13.9 0.0 0.081 13.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein family UPF0004 DUF512 PF04459.12 EST48770.1 - 0.047 13.0 0.0 0.055 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF512) Snf7 PF03357.21 EST48772.1 - 6.3e-07 29.1 13.7 8.5e-07 28.7 13.7 1.2 1 0 0 1 1 1 1 Snf7 PspA_IM30 PF04012.12 EST48772.1 - 0.0053 16.4 16.6 0.089 12.4 16.6 2.0 1 1 0 1 1 1 1 PspA/IM30 family NUC194 PF08163.12 EST48772.1 - 0.046 12.7 5.7 0.051 12.5 5.7 1.1 1 0 0 1 1 1 0 NUC194 domain DUF4355 PF14265.6 EST48772.1 - 0.056 13.7 10.8 0.092 13.0 10.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) COMM_domain PF07258.14 EST48772.1 - 0.068 13.3 2.8 0.57 10.3 2.8 2.3 1 1 0 1 1 1 0 COMM domain TMPIT PF07851.13 EST48772.1 - 0.23 10.7 6.2 0.29 10.3 6.2 1.3 1 0 0 1 1 1 0 TMPIT-like protein NBD_C PF17042.5 EST48772.1 - 0.37 11.3 4.3 18 5.8 4.1 2.1 1 1 1 2 2 2 0 Nucleotide-binding C-terminal domain YlqD PF11068.8 EST48772.1 - 2.1 8.7 17.0 1.6e+02 2.6 17.0 2.1 1 1 0 1 1 1 0 YlqD protein ZnuA PF01297.17 EST48772.1 - 3.3 7.1 7.2 10 5.5 7.1 1.7 1 1 1 2 2 2 0 Zinc-uptake complex component A periplasmic Calici_MSP PF05752.11 EST48772.1 - 3.3 7.5 8.1 1.2 8.9 0.2 2.5 1 1 2 3 3 3 0 Calicivirus minor structural protein TFR_dimer PF04253.15 EST48772.1 - 3.8 7.6 7.4 27 4.9 0.1 2.5 1 1 0 2 2 2 0 Transferrin receptor-like dimerisation domain Myb_DNA-binding PF00249.31 EST48773.1 - 2.9e-06 27.4 0.0 4.7e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST48773.1 - 0.0023 18.1 0.0 0.0036 17.5 0.0 1.4 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST48773.1 - 0.21 11.5 0.0 0.3 11.0 0.0 1.1 1 0 0 1 1 1 0 Myb DNA-binding like UPF0004 PF00919.20 EST48774.1 - 0.036 14.1 0.0 0.062 13.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein family UPF0004 DUF512 PF04459.12 EST48774.1 - 0.076 12.3 0.0 0.09 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF512) Nucleoside_tran PF01733.18 EST48775.1 - 5.9e-22 78.4 16.3 5.9e-22 78.4 16.3 2.4 1 1 1 2 2 2 1 Nucleoside transporter Pkinase PF00069.25 EST48777.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain MMR_HSR1 PF01926.23 EST48779.1 - 1.1e-17 64.1 0.1 4.1e-13 49.4 0.0 2.7 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EST48779.1 - 6e-09 35.6 0.0 0.00011 21.8 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 EST48779.1 - 5e-06 26.2 0.1 3e-05 23.6 0.0 2.2 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EST48779.1 - 8.8e-05 22.6 1.6 0.029 14.4 0.0 3.1 3 1 0 3 3 3 1 Dynamin family AAA_16 PF13191.6 EST48779.1 - 0.004 17.6 0.1 0.14 12.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EST48779.1 - 0.0044 16.9 0.0 3.9 7.4 0.0 2.9 1 1 0 2 2 2 2 RsgA GTPase cobW PF02492.19 EST48779.1 - 0.019 14.5 0.1 0.13 11.8 0.0 2.2 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 EST48779.1 - 0.029 14.9 0.1 0.2 12.2 0.0 2.4 2 1 1 3 3 3 0 AAA domain GN3L_Grn1 PF08701.11 EST48779.1 - 0.085 13.0 12.6 0.52 10.5 12.6 2.2 1 1 0 1 1 1 0 GNL3L/Grn1 putative GTPase PduV-EutP PF10662.9 EST48779.1 - 0.097 12.4 0.0 0.37 10.5 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Nucleoside_tran PF01733.18 EST48781.1 - 1e-09 38.2 8.1 2.6e-09 36.9 8.1 1.6 1 1 0 1 1 1 1 Nucleoside transporter DUF347 PF03988.12 EST48781.1 - 0.26 11.5 8.1 1 9.6 0.2 2.8 3 0 0 3 3 3 0 Repeat of Unknown Function (DUF347) adh_short PF00106.25 EST48782.1 - 3.6e-11 42.9 0.0 5.6e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EST48782.1 - 4.2e-06 26.8 0.0 6.7e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EST48782.1 - 0.0012 18.8 0.0 0.0054 16.6 0.0 2.0 3 0 0 3 3 3 1 NAD(P)H-binding adh_short_C2 PF13561.6 EST48782.1 - 0.0067 16.0 0.0 0.0089 15.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PALP PF00291.25 EST48784.1 - 1.4e-60 205.2 0.0 1.6e-60 205.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme RIIa PF02197.17 EST48785.1 - 0.013 15.1 0.1 0.027 14.1 0.1 1.6 1 1 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit adh_short PF00106.25 EST48788.1 - 3.6e-11 42.9 0.0 5.6e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EST48788.1 - 4.2e-06 26.8 0.0 6.7e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EST48788.1 - 0.0012 18.8 0.0 0.0054 16.6 0.0 2.0 3 0 0 3 3 3 1 NAD(P)H-binding adh_short_C2 PF13561.6 EST48788.1 - 0.0067 16.0 0.0 0.0089 15.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase SseB_C PF14581.6 EST48789.1 - 0.015 15.4 0.0 0.055 13.6 0.0 2.0 1 0 0 1 1 1 0 SseB protein C-terminal domain DUF3452 PF11934.8 EST48789.1 - 0.47 10.0 4.2 2.6 7.6 0.2 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3452) VSP PF03302.13 EST48790.1 - 2.4e-06 26.7 110.2 0.0025 16.7 20.2 5.1 1 1 4 5 5 5 5 Giardia variant-specific surface protein Bacteriocin_IIc PF10439.9 EST48790.1 - 0.14 12.3 6.4 0.32 11.1 6.4 1.5 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DUF3042 PF11240.8 EST48790.1 - 1.7 8.8 4.2 3 7.9 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) VSP PF03302.13 EST48791.1 - 4.1e-06 25.9 38.2 0.0038 16.1 14.1 2.0 1 1 1 2 2 2 2 Giardia variant-specific surface protein Glucokinase PF02685.16 EST48792.1 - 2.7e-33 115.3 0.0 3.3e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Glucokinase ROK PF00480.20 EST48792.1 - 6.7e-05 22.5 0.1 0.00012 21.7 0.1 1.4 1 1 0 1 1 1 1 ROK family Kri1_C PF12936.7 EST48793.1 - 0.0011 19.2 0.1 0.0011 19.2 0.1 3.6 4 1 0 4 4 4 1 KRI1-like family C-terminal tRNA-synt_2b PF00587.25 EST48795.1 - 7.3e-34 117.3 0.0 5.8e-32 111.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_SAD PF07973.14 EST48795.1 - 3.3e-12 46.3 0.0 8.7e-11 41.8 0.0 2.4 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain HGTP_anticodon PF03129.20 EST48795.1 - 4e-09 36.5 0.0 9.1e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain VSP PF03302.13 EST48796.1 - 0.0039 16.1 19.4 0.0039 16.1 19.4 2.1 1 1 1 2 2 2 1 Giardia variant-specific surface protein Syndecan PF01034.20 EST48796.1 - 0.0047 16.8 0.1 0.0081 16.1 0.1 1.4 1 0 0 1 1 1 1 Syndecan domain TMEM154 PF15102.6 EST48796.1 - 0.016 15.1 0.1 0.025 14.5 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family FixQ PF05545.11 EST48796.1 - 0.026 14.5 0.0 0.041 13.9 0.0 1.2 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ DUF5385 PF17359.2 EST48796.1 - 0.03 13.9 0.6 0.038 13.6 0.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5385) DUF2207 PF09972.9 EST48796.1 - 0.034 12.9 0.0 0.043 12.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Stevor PF17410.2 EST48796.1 - 0.039 13.5 0.0 0.039 13.5 0.0 1.8 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame Glycophorin_A PF01102.18 EST48796.1 - 0.058 13.6 0.0 0.092 13.0 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A BatA PF07584.11 EST48796.1 - 0.15 12.4 0.8 0.23 11.8 0.8 1.2 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal Otopetrin PF03189.13 EST48796.1 - 0.17 10.7 0.2 0.36 9.6 0.0 1.6 2 0 0 2 2 2 0 Otopetrin PTH2 PF01981.16 EST48797.1 - 4.4e-13 49.5 0.0 4.5e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 KBP_C PF12309.8 EST48798.1 - 1.1e-19 71.3 10.1 2.1e-17 63.7 8.3 3.0 2 1 0 2 2 2 1 KIF-1 binding protein C terminal Pkinase PF00069.25 EST48800.1 - 9.7e-39 133.3 5.0 2.5e-34 118.8 0.2 3.6 3 1 1 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 EST48800.1 - 2.6e-22 79.4 0.1 3.1e-20 72.6 0.0 2.9 2 1 1 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.6 EST48800.1 - 3.6e-05 23.2 0.0 0.00011 21.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EST48800.1 - 0.026 13.3 0.0 0.045 12.5 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase CBS PF00571.28 EST48801.1 - 4.8e-27 94.2 1.5 3.3e-06 27.5 0.1 4.2 4 0 0 4 4 4 4 CBS domain Syndecan PF01034.20 EST48802.1 - 0.00068 19.5 0.1 0.0011 18.8 0.1 1.3 1 0 0 1 1 1 1 Syndecan domain Glycophorin_A PF01102.18 EST48802.1 - 0.0021 18.3 0.0 0.003 17.8 0.0 1.2 1 0 0 1 1 1 1 Glycophorin A DUF485 PF04341.12 EST48802.1 - 0.035 14.1 0.0 0.048 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF485 TMEM154 PF15102.6 EST48802.1 - 0.047 13.6 0.0 0.066 13.1 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family DUF5385 PF17359.2 EST48802.1 - 0.051 13.1 0.3 0.091 12.3 0.2 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF5385) CcmD PF04995.14 EST48802.1 - 0.16 12.1 0.1 0.23 11.6 0.1 1.2 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Fe_hyd_lg_C PF02906.14 EST48803.1 - 3e-65 220.3 0.2 7e-65 219.1 0.1 1.5 2 0 0 2 2 2 1 Iron only hydrogenase large subunit, C-terminal domain Fer4 PF00037.27 EST48803.1 - 2e-08 33.7 20.9 2.2e-06 27.3 4.9 3.4 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_9 PF13187.6 EST48803.1 - 1.4e-07 31.5 9.9 1.4e-07 31.5 9.9 2.8 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 EST48803.1 - 2.7e-07 31.1 11.2 2.7e-07 31.1 11.2 2.8 3 1 0 3 3 2 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EST48803.1 - 1.1e-06 29.5 11.6 0.00056 20.8 1.8 3.6 3 0 0 3 3 3 2 4Fe-4S double cluster binding domain Fer4_17 PF13534.6 EST48803.1 - 1.3e-05 25.6 8.2 1.3e-05 25.6 8.2 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 EST48803.1 - 3.9e-05 23.7 13.3 3.9e-05 23.7 13.3 3.7 4 1 1 5 5 5 2 4Fe-4S dicluster domain Fe_hyd_SSU PF02256.17 EST48803.1 - 0.00035 20.6 0.0 0.00093 19.2 0.0 1.8 1 0 0 1 1 1 1 Iron hydrogenase small subunit Fer4_6 PF12837.7 EST48803.1 - 0.0011 19.0 4.8 0.0011 19.0 4.8 3.6 4 0 0 4 4 3 2 4Fe-4S binding domain Fer4_8 PF13183.6 EST48803.1 - 0.0011 19.4 10.1 0.0011 19.4 10.1 2.7 2 1 1 3 3 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EST48803.1 - 0.0014 18.7 19.8 0.0031 17.6 14.2 3.3 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 EST48803.1 - 0.0039 18.0 7.5 0.0039 18.0 7.5 4.2 4 0 0 4 4 4 1 4Fe-4S binding domain Fer4_18 PF13746.6 EST48803.1 - 0.026 14.7 4.9 0.026 14.7 4.9 3.1 2 1 0 3 3 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 EST48803.1 - 0.026 14.6 6.8 0.026 14.6 6.8 3.6 4 0 0 4 4 2 0 4Fe-4S binding domain Fer4_4 PF12800.7 EST48803.1 - 0.028 14.9 4.8 0.028 14.9 4.8 3.3 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 EST48803.1 - 0.085 13.7 15.3 0.09 13.6 0.9 3.2 4 0 0 4 4 3 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 EST48803.1 - 0.19 12.5 11.6 1.1 10.1 1.9 3.6 3 0 0 3 3 3 0 4Fe-4S single cluster domain Fer4_13 PF13370.6 EST48803.1 - 3 8.5 17.1 1.7 9.3 0.4 3.3 3 0 0 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I tRNA-synt_2 PF00152.20 EST48804.1 - 8.4e-77 258.3 0.1 1.2e-76 257.8 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EST48804.1 - 5.3e-08 32.7 0.1 1.1e-07 31.7 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EST48804.1 - 0.00011 21.8 0.2 0.079 12.4 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Ery_res_leader1 PF08051.11 EST48805.1 - 0.3 11.3 1.0 1.3 9.4 0.1 2.4 2 0 0 2 2 2 0 Erythromycin resistance leader peptide MORN PF02493.20 EST48806.1 - 9.6e-28 94.4 51.2 0.00073 19.3 0.1 15.3 17 0 0 17 17 17 10 MORN repeat ID PF18543.1 EST48806.1 - 0.86 9.7 9.1 7.5 6.7 0.2 5.2 6 0 0 6 6 6 0 Intracellular delivery domain NGP1NT PF08153.12 EST48809.1 - 1.1e-29 103.1 1.2 2.9e-29 101.9 1.2 1.7 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 EST48809.1 - 6.4e-17 61.7 0.1 4e-13 49.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EST48809.1 - 1e-08 35.3 0.0 3.4e-08 33.6 0.0 1.8 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 EST48809.1 - 8.2e-07 28.7 0.1 7.9e-05 22.2 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 EST48809.1 - 0.00043 19.8 0.7 0.32 10.4 0.1 3.2 3 0 0 3 3 3 2 ADP-ribosylation factor family GTP_EFTU PF00009.27 EST48809.1 - 0.005 16.4 0.6 0.039 13.5 0.0 2.7 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 EST48809.1 - 0.023 14.0 0.0 0.2 11.0 0.0 2.3 2 0 0 2 2 2 0 AIG1 family Dynamin_N PF00350.23 EST48809.1 - 0.025 14.7 0.1 0.025 14.7 0.1 3.9 3 1 1 4 4 4 0 Dynamin family Glyco_hydro_81 PF03639.13 EST48809.1 - 0.16 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 81 N-terminal domain ABC_tran PF00005.27 EST48809.1 - 0.58 10.7 3.7 0.78 10.2 0.0 2.9 3 1 0 3 3 3 0 ABC transporter YlqD PF11068.8 EST48811.1 - 0.033 14.6 5.5 0.096 13.1 5.5 1.7 1 0 0 1 1 1 0 YlqD protein Phage_Mu_Gam PF07352.12 EST48811.1 - 0.048 13.6 2.1 0.11 12.4 2.1 1.5 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein ABC_tran_CTD PF16326.5 EST48811.1 - 0.097 12.9 1.2 0.25 11.6 1.2 1.7 1 0 0 1 1 1 0 ABC transporter C-terminal domain Baculo_PEP_C PF04513.12 EST48811.1 - 4 7.5 10.1 0.96 9.5 5.2 2.4 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus MMR_HSR1_Xtn PF16897.5 EST48812.1 - 1.8e-33 114.7 1.6 3.9e-33 113.6 1.6 1.6 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EST48812.1 - 7.9e-19 67.8 0.0 1.5e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 EST48812.1 - 1.7e-17 63.2 0.3 4e-17 62.0 0.3 1.7 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 EST48812.1 - 1.6e-11 43.9 0.1 3e-11 43.1 0.1 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EST48812.1 - 7.9e-05 22.8 0.2 0.027 14.5 0.0 2.4 2 0 0 2 2 2 2 Dynamin family YchF-GTPase_C PF06071.13 EST48812.1 - 0.1 12.8 0.3 10 6.4 0.3 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF933) DUF2292 PF10055.9 EST48812.1 - 1.7 8.3 4.8 28 4.4 3.9 2.6 2 0 0 2 2 2 0 Uncharacterized small protein (DUF2292) Peptidase_C1 PF00112.23 EST48814.1 - 1.1e-30 107.4 0.0 3e-30 105.9 0.0 1.8 1 1 0 1 1 1 1 Papain family cysteine protease NUDIX PF00293.28 EST48816.1 - 1.7e-11 44.3 0.0 2.3e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DHHC PF01529.20 EST48818.1 - 2.5e-15 56.8 9.5 2.5e-15 56.8 9.5 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF4501 PF14946.6 EST48818.1 - 0.0011 19.1 0.1 0.0025 17.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4501) LMSTEN PF07988.12 EST48819.1 - 0.063 12.8 0.1 0.23 11.0 0.0 1.9 2 0 0 2 2 2 0 LMSTEN motif Glucokinase PF02685.16 EST48820.1 - 3.1e-59 200.5 0.0 3.5e-59 200.4 0.0 1.0 1 0 0 1 1 1 1 Glucokinase ROK PF00480.20 EST48820.1 - 1.3e-09 37.9 0.0 2.6e-09 37.0 0.0 1.4 1 1 0 1 1 1 1 ROK family Hexokinase_1 PF00349.21 EST48820.1 - 0.17 11.8 0.1 4.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Hexokinase zf-C3HC4_2 PF13923.6 EST48821.1 - 0.13 12.1 10.6 0.29 11.0 10.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EST48821.1 - 0.15 12.0 8.8 0.44 10.4 8.8 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EST48821.1 - 0.16 12.1 8.1 0.085 12.9 5.6 1.9 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EST48821.1 - 1.2 9.3 10.9 3.9 7.7 10.9 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING RNA_pol_Rpc34 PF05158.12 EST48822.1 - 1.9e-08 34.1 7.1 2e-08 34.0 4.7 2.2 1 1 1 2 2 2 1 RNA polymerase Rpc34 subunit Peptidase_C1 PF00112.23 EST48823.1 - 1.5e-31 110.2 8.9 1.8e-30 106.7 8.9 2.4 1 1 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EST48823.1 - 0.0057 15.5 3.1 0.44 9.3 0.6 2.4 2 0 0 2 2 2 2 Peptidase C1-like family Type2_restr_D3 PF16902.5 EST48826.1 - 0.096 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Type-2 restriction enzyme D3 domain Pkinase PF00069.25 EST48827.1 - 9e-69 231.8 0.0 1.1e-68 231.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST48827.1 - 1.4e-31 109.8 0.0 2.2e-31 109.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EST48827.1 - 0.00024 20.5 1.4 0.00064 19.1 0.2 2.2 2 1 1 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 EST48827.1 - 0.00027 20.0 2.2 0.0011 18.0 2.2 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EST48827.1 - 0.072 12.4 0.5 0.14 11.5 0.5 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pho86 PF11124.8 EST48828.1 - 0.078 12.4 0.3 0.17 11.3 0.1 1.4 1 1 0 1 1 1 0 Inorganic phosphate transporter Pho86 TPK_catalytic PF04263.16 EST48829.1 - 1.2e-12 48.0 0.1 1.8e-12 47.3 0.1 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 EST48829.1 - 1.4e-06 27.9 0.0 2.7e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain MCM PF00493.23 EST48831.1 - 2.1e-82 275.6 0.1 4.3e-82 274.6 0.1 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 EST48831.1 - 4.4e-20 71.9 0.2 8.7e-20 70.9 0.2 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 EST48831.1 - 4.6e-16 58.8 0.9 1.2e-15 57.5 0.9 1.7 1 0 0 1 1 1 1 MCM OB domain AAA_5 PF07728.14 EST48831.1 - 3.4e-08 33.6 0.0 1.4e-07 31.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EST48831.1 - 4.3e-08 32.8 0.1 1.9e-06 27.4 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EST48831.1 - 5.8e-06 26.2 0.0 1.3e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 EST48831.1 - 7.2e-05 23.0 0.0 0.00016 21.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.26 EST48831.1 - 0.0029 17.3 0.2 0.012 15.3 0.2 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain DUF1128 PF06569.11 EST48831.1 - 0.035 14.1 0.0 0.21 11.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) Lactamase_B_5 PF14597.6 EST48831.1 - 0.038 13.5 0.0 0.1 12.0 0.0 1.7 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Pkinase PF00069.25 EST48833.1 - 5.2e-40 137.5 0.5 1.1e-36 126.6 0.2 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EST48833.1 - 1.8e-23 83.2 0.2 2e-22 79.7 0.0 2.4 2 1 1 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.6 EST48833.1 - 4e-05 23.1 0.0 0.0002 20.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EST48833.1 - 0.00044 19.3 0.1 0.0032 16.5 0.1 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EST48833.1 - 0.058 12.2 0.0 0.12 11.1 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Hormone_4 PF00220.17 EST48833.1 - 0.25 11.4 2.3 0.89 9.7 2.3 2.0 1 0 0 1 1 1 0 Neurohypophysial hormones, N-terminal Domain Metallophos PF00149.28 EST48834.1 - 7e-09 36.5 3.0 7e-09 36.5 3.0 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Choline_transpo PF04515.12 EST48835.1 - 6e-46 157.1 48.7 6e-46 157.1 48.7 2.9 3 0 0 3 3 3 2 Plasma-membrane choline transporter Glyco_transf_21 PF13506.6 EST48842.1 - 3e-08 33.3 0.0 4.7e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 EST48842.1 - 8e-07 29.2 0.9 1.5e-06 28.3 0.9 1.3 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EST48842.1 - 0.00043 20.3 0.0 0.00076 19.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EST48842.1 - 0.012 15.4 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 DEAD PF00270.29 EST48844.1 - 2e-26 92.8 0.6 6.8e-26 91.1 0.2 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EST48844.1 - 1e-21 77.4 1.3 2.1e-20 73.1 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EST48844.1 - 2.2e-06 27.8 0.1 2.3e-05 24.5 0.0 2.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 EST48844.1 - 0.017 15.1 0.0 0.042 13.8 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_22 PF13401.6 EST48844.1 - 0.12 12.7 3.1 6.9 7.0 2.7 3.1 2 1 0 2 2 2 0 AAA domain Kinesin PF00225.23 EST48846.1 - 1.4e-35 122.8 0.3 3e-35 121.7 0.3 1.6 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EST48846.1 - 8.8e-08 32.2 0.0 4.6e-07 29.9 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding YcaO PF02624.16 EST48846.1 - 0.061 12.6 0.0 0.089 12.1 0.0 1.3 1 0 0 1 1 1 0 YcaO cyclodehydratase, ATP-ad Mg2+-binding LSM PF01423.22 EST48847.1 - 1.5e-16 59.9 1.2 2.7e-16 59.0 1.2 1.4 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EST48847.1 - 0.025 14.7 0.2 0.036 14.2 0.2 1.6 1 1 0 1 1 1 0 Ataxin 2 SM domain NusG PF02357.19 EST48847.1 - 0.11 13.0 0.0 0.17 12.4 0.0 1.3 1 0 0 1 1 1 0 Transcription termination factor nusG Methyltr_RsmB-F PF01189.17 EST48848.1 - 1.2e-58 198.1 0.0 1.7e-58 197.6 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 EST48848.1 - 1.9e-13 50.7 0.0 3.7e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF PCMT PF01135.19 EST48848.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DFRP_C PF16543.5 EST48849.1 - 4.7e-12 46.2 3.3 4.7e-12 46.2 3.3 3.2 3 1 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 RapA_C PF12137.8 EST48849.1 - 1.9 7.4 12.0 5.1 6.0 9.2 2.3 2 0 0 2 2 2 0 RNA polymerase recycling family C-terminal MgsA_C PF12002.8 EST48849.1 - 2.2 8.2 7.4 1 9.3 2.4 2.4 1 1 0 2 2 2 0 MgsA AAA+ ATPase C terminal Torus PF16131.5 EST48849.1 - 2.6 8.8 21.5 0.075 13.7 4.8 4.0 3 3 0 3 3 3 0 Torus domain SlyX PF04102.12 EST48850.1 - 6.3 7.5 7.6 0.37 11.5 2.0 1.8 2 0 0 2 2 2 0 SlyX NRBF2 PF08961.10 EST48851.1 - 0.011 15.4 0.0 0.027 14.1 0.0 1.6 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator Defensin_5 PF18251.1 EST48851.1 - 0.028 14.5 0.9 0.081 13.0 0.9 1.8 1 0 0 1 1 1 0 Fungal defensin Copsin DivIC PF04977.15 EST48851.1 - 0.13 12.1 0.3 0.47 10.2 0.1 2.0 2 0 0 2 2 2 0 Septum formation initiator bZIP_2 PF07716.15 EST48851.1 - 5.7 7.1 6.2 17 5.6 0.1 3.6 4 0 0 4 4 4 0 Basic region leucine zipper Pkinase PF00069.25 EST48853.1 - 1e-64 218.4 0.0 1.4e-64 218.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST48853.1 - 4.6e-34 117.9 0.0 3.5e-33 115.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EST48853.1 - 1.1e-05 25.0 1.2 6.4e-05 22.4 1.2 2.0 1 1 0 1 1 1 1 Kinase-like WaaY PF06176.11 EST48853.1 - 2.9e-05 23.8 0.3 4.4e-05 23.2 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase_fungal PF17667.1 EST48853.1 - 0.00061 18.7 0.0 0.00089 18.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EST48853.1 - 0.0014 18.0 0.7 0.0028 17.1 0.7 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EST48853.1 - 0.0085 15.7 0.3 0.077 12.6 0.0 2.1 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EST48853.1 - 0.0088 15.7 0.7 0.023 14.3 0.2 2.0 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 EST48853.1 - 0.016 15.2 0.3 3.5 7.5 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 EST48853.1 - 0.058 12.9 0.2 0.13 11.7 0.2 1.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL SlyX PF04102.12 EST48854.1 - 0.04 14.5 1.8 0.053 14.1 1.8 1.4 1 0 0 1 1 1 0 SlyX Aerolysin PF01117.20 EST48856.1 - 0.017 14.4 0.5 0.024 13.9 0.5 1.2 1 0 0 1 1 1 0 Aerolysin toxin Cep57_CLD PF14073.6 EST48856.1 - 2.3 8.2 7.2 1.2 9.1 2.8 1.9 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 MIP-T3 PF10243.9 EST48857.1 - 8.2e-20 70.9 2.7 4.8e-10 39.4 0.2 2.7 2 0 0 2 2 2 2 Microtubule-binding protein MIP-T3 CH-like domain DnaB PF00772.21 EST48857.1 - 0.01 15.9 0.6 0.068 13.2 0.1 2.6 2 1 1 3 3 3 0 DnaB-like helicase N terminal domain DUF4205 PF13898.6 EST48858.1 - 2.3e-47 161.6 0.5 4e-47 160.8 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) UBA PF00627.31 EST48860.1 - 1.1e-06 28.4 0.1 1.1e-06 28.4 0.1 2.3 2 0 0 2 2 2 1 UBA/TS-N domain STI1 PF17830.1 EST48860.1 - 0.00012 22.0 12.5 0.00012 22.0 12.5 6.4 3 2 3 6 6 6 2 STI1 domain XPC-binding PF09280.11 EST48860.1 - 0.0011 18.7 29.5 0.11 12.3 14.0 4.3 2 2 0 2 2 2 2 XPC-binding domain Rad60-SLD PF11976.8 EST48860.1 - 0.0013 18.5 2.4 0.0018 18.1 0.5 2.3 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like CUE PF02845.16 EST48860.1 - 0.015 15.0 0.5 0.015 15.0 0.5 3.2 4 0 0 4 4 4 0 CUE domain ubiquitin PF00240.23 EST48860.1 - 0.35 10.7 2.8 1.6 8.5 0.6 2.5 1 1 1 2 2 2 0 Ubiquitin family GerD PF17898.1 EST48860.1 - 0.39 10.7 41.5 0.08 12.9 12.9 3.5 3 1 0 3 3 3 0 Spore germination GerD central core domain DUF2203 PF09969.9 EST48860.1 - 3.2 8.5 7.0 1.1 10.0 0.1 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) Amidinotransf PF02274.17 EST48861.1 - 4.5e-51 173.9 0.0 2.8e-49 168.0 0.0 2.1 2 0 0 2 2 2 2 Amidinotransferase PAD_porph PF04371.15 EST48861.1 - 0.057 12.7 0.2 5.6 6.1 0.0 2.2 2 0 0 2 2 2 0 Porphyromonas-type peptidyl-arginine deiminase Fez1 PF06818.15 EST48862.1 - 0.22 12.0 26.5 0.091 13.2 1.8 3.0 2 1 1 3 3 3 0 Fez1 PSRP-3_Ycf65 PF04839.13 EST48862.1 - 2.3 8.5 4.3 28 5.0 0.1 3.5 3 0 0 3 3 3 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) NPV_P10 PF05531.12 EST48862.1 - 7.5 7.1 15.3 0.92 10.0 0.9 4.2 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein MatE PF01554.18 EST48863.1 - 0.0022 17.6 6.9 0.0022 17.6 6.9 3.4 4 0 0 4 4 4 2 MatE LRR_6 PF13516.6 EST48864.1 - 1.8e-11 43.1 43.5 0.049 13.7 0.0 12.2 14 0 0 14 14 14 6 Leucine Rich repeat LRR_4 PF12799.7 EST48864.1 - 0.0033 17.8 49.0 0.052 14.0 2.7 8.4 5 3 4 9 9 9 7 Leucine Rich repeats (2 copies) DUF4201 PF13870.6 EST48868.1 - 8.7e-05 22.3 16.4 8.7e-05 22.3 16.4 2.4 1 1 0 2 2 2 1 Domain of unknown function (DUF4201) FemAB_like PF04339.12 EST48868.1 - 0.006 15.8 0.8 0.011 14.9 0.8 1.4 1 1 0 1 1 1 1 Peptidogalycan biosysnthesis/recognition DUF641 PF04859.12 EST48868.1 - 0.0072 16.7 21.1 0.069 13.5 0.7 3.4 3 0 0 3 3 3 2 Plant protein of unknown function (DUF641) HAP1_N PF04849.13 EST48868.1 - 0.016 14.4 29.8 0.52 9.5 28.0 2.2 1 1 1 2 2 2 0 HAP1 N-terminal conserved region Lebercilin PF15619.6 EST48868.1 - 0.018 14.7 3.3 0.018 14.7 3.3 3.2 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease ADIP PF11559.8 EST48868.1 - 0.021 14.9 28.1 0.024 14.7 6.9 3.4 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF2730 PF10805.8 EST48868.1 - 0.06 13.5 0.3 0.06 13.5 0.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) Baculo_PEP_C PF04513.12 EST48868.1 - 0.061 13.4 10.4 0.13 12.3 5.3 2.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.6 EST48868.1 - 0.078 12.3 31.0 0.076 12.3 7.8 2.6 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 EST48868.1 - 0.2 10.5 33.0 0.088 11.7 14.7 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF4200 PF13863.6 EST48868.1 - 0.28 11.6 30.2 1 9.7 9.5 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) Filament PF00038.21 EST48868.1 - 0.36 10.4 25.3 0.45 10.0 6.8 3.1 1 1 2 3 3 3 0 Intermediate filament protein UPF0242 PF06785.11 EST48868.1 - 0.92 9.6 35.2 0.21 11.7 9.6 2.8 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Phage_GP20 PF06810.11 EST48868.1 - 1.1 9.1 23.1 5.9 6.7 0.9 3.4 2 1 0 3 3 3 0 Phage minor structural protein GP20 FAM76 PF16046.5 EST48868.1 - 1.3 8.3 20.9 0.088 12.2 9.1 2.2 2 0 0 2 2 2 0 FAM76 protein Bacillus_HBL PF05791.11 EST48868.1 - 1.5 8.6 21.0 0.81 9.5 4.5 3.2 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) IFT57 PF10498.9 EST48868.1 - 1.6 7.6 26.1 0.61 9.0 11.9 3.0 1 1 1 3 3 3 0 Intra-flagellar transport protein 57 KASH_CCD PF14662.6 EST48868.1 - 3.1 7.6 31.2 0.24 11.2 14.2 3.1 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH DUF4407 PF14362.6 EST48868.1 - 4 6.7 17.2 0.62 9.4 7.0 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 EST48868.1 - 4.7 7.6 25.2 4.4e+02 1.2 24.7 2.4 1 1 0 1 1 1 0 Fez1 ATG16 PF08614.11 EST48868.1 - 8.6 6.5 32.1 0.18 12.0 16.9 2.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Snf7 PF03357.21 EST48869.1 - 2.5e-06 27.2 29.0 3.7e-06 26.7 29.0 1.3 1 0 0 1 1 1 1 Snf7 TcdB_N PF12918.7 EST48869.1 - 0.03 14.6 0.9 0.08 13.3 0.9 1.9 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain DUF2203 PF09969.9 EST48869.1 - 2.9 8.7 14.5 4.1 8.2 4.9 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Myb_DNA-binding PF00249.31 EST48871.1 - 2.2e-05 24.5 0.0 3.3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EST48871.1 - 0.018 15.2 0.2 0.039 14.1 0.2 1.6 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 eIF-5_eIF-2B PF01873.17 EST48872.1 - 1e-19 70.5 2.5 2.2e-19 69.5 2.5 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 zf-HYPF PF07503.12 EST48872.1 - 0.031 14.0 0.9 0.17 11.7 0.0 2.2 2 0 0 2 2 2 0 HypF finger Zn_Tnp_IS1595 PF12760.7 EST48872.1 - 0.06 13.3 0.3 0.16 12.0 0.1 1.8 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF3793 PF12672.7 EST48873.1 - 0.11 12.5 6.6 0.39 10.7 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3793) DUF2175 PF09943.9 EST48873.1 - 0.15 12.4 9.4 1.3 9.3 2.9 3.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) DUF2267 PF10025.9 EST48873.1 - 7.1 6.9 5.6 13 6.0 0.1 3.2 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2267) APC_rep PF18797.1 EST48874.1 - 0.034 15.1 2.2 9.2 7.3 0.5 3.4 2 0 0 2 2 2 0 Adenomatous polyposis coli (APC) repeat Frataxin_Cyay PF01491.16 EST48875.1 - 2.1e-18 66.4 0.0 2.2e-18 66.3 0.0 1.0 1 0 0 1 1 1 1 Frataxin-like domain Glucosamine_iso PF01182.20 EST48876.1 - 1.2e-23 84.2 0.0 1.8e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase VSP PF03302.13 EST48877.1 - 3.1e-11 42.8 229.2 0.0061 15.5 34.9 8.9 1 1 6 8 8 8 7 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EST48877.1 - 0.003 17.7 210.1 0.034 14.3 31.2 11.9 1 1 9 11 11 11 6 Furin-like repeat, cysteine-rich Dickkopf_N PF04706.12 EST48877.1 - 0.0059 17.1 17.5 0.0059 17.1 17.5 13.5 4 4 9 13 13 13 3 Dickkopf N-terminal cysteine-rich region Furin-like_2 PF15913.5 EST48879.1 - 3.6e-05 23.9 129.7 0.38 10.9 19.9 8.7 1 1 7 8 8 8 7 Furin-like repeat, cysteine-rich VSP PF03302.13 EST48879.1 - 4.4e-05 22.5 148.2 0.03 13.2 86.7 4.9 1 1 3 4 4 4 3 Giardia variant-specific surface protein Podoplanin PF05808.11 EST48879.1 - 0.031 14.4 0.2 0.053 13.6 0.2 1.3 1 0 0 1 1 1 0 Podoplanin Furin-like_2 PF15913.5 EST48881.1 - 3.7e-05 23.8 25.5 0.00098 19.3 15.9 2.1 1 1 1 2 2 2 2 Furin-like repeat, cysteine-rich CYYR1 PF10873.8 EST48881.1 - 0.0024 18.3 4.5 0.0024 18.3 4.5 2.0 1 1 1 2 2 2 1 Cysteine and tyrosine-rich protein 1 VSP PF03302.13 EST48881.1 - 0.0043 16.0 27.3 0.0043 16.0 27.3 2.0 1 1 1 2 2 2 1 Giardia variant-specific surface protein Dickkopf_N PF04706.12 EST48881.1 - 0.015 15.8 14.7 0.015 15.8 14.7 2.4 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region DUF1043 PF06295.12 EST48881.1 - 0.082 12.9 0.2 0.13 12.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Tad PF13400.6 EST48881.1 - 0.1 12.9 3.4 0.14 12.5 3.4 1.2 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like EphA2_TM PF14575.6 EST48881.1 - 0.23 12.4 0.3 0.54 11.2 0.0 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Podoplanin PF05808.11 EST48881.1 - 2.3 8.3 4.6 4.5 7.4 4.8 1.3 1 1 0 1 1 1 0 Podoplanin F420_ligase PF01996.16 EST48883.1 - 8.6e-36 123.5 0.0 9.8e-36 123.3 0.0 1.0 1 0 0 1 1 1 1 F420-0:Gamma-glutamyl ligase DUF1788 PF08747.11 EST48883.1 - 0.034 14.2 0.1 0.043 13.8 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1788) F420_ligase PF01996.16 EST48884.1 - 8.8e-27 94.0 0.0 9.7e-27 93.9 0.0 1.0 1 0 0 1 1 1 1 F420-0:Gamma-glutamyl ligase FANCL_C PF11793.8 EST48885.1 - 0.033 14.4 6.4 11 6.3 0.2 3.6 3 0 0 3 3 3 0 FANCL C-terminal domain zf-NOSIP PF15906.5 EST48885.1 - 1.2 9.3 4.8 47 4.2 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger of nitric oxide synthase-interacting protein DUF2407_C PF13373.6 EST48886.1 - 0.038 14.2 1.4 0.038 14.1 1.4 1.1 1 0 0 1 1 1 0 DUF2407 C-terminal domain DUF5326 PF17260.2 EST48886.1 - 1.8 8.8 8.2 0.2 11.8 1.7 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5326) Syndecan PF01034.20 EST48886.1 - 4.7 7.2 6.9 0.96 9.4 1.1 2.0 2 0 0 2 2 2 0 Syndecan domain RPM2 PF08579.11 EST48888.1 - 6.4e-05 23.3 4.7 8.3e-05 23.0 4.7 1.3 1 1 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) Asparaginase PF00710.20 EST48888.1 - 0.13 11.8 0.3 0.21 11.1 0.3 1.2 1 0 0 1 1 1 0 Asparaginase, N-terminal PIN PF01850.21 EST48889.1 - 0.11 13.0 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 PIN domain CYYR1 PF10873.8 EST48890.1 - 0.0093 16.4 0.4 0.0093 16.4 0.4 2.1 2 1 1 3 3 3 1 Cysteine and tyrosine-rich protein 1 Phage_holin_3_6 PF07332.11 EST48890.1 - 0.011 15.8 0.1 0.015 15.3 0.1 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Syndecan PF01034.20 EST48890.1 - 0.019 14.9 0.3 0.032 14.1 0.3 1.3 1 0 0 1 1 1 0 Syndecan domain Bacteriocin_IIc PF10439.9 EST48890.1 - 0.055 13.6 1.8 0.093 12.9 1.8 1.3 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Podoplanin PF05808.11 EST48890.1 - 0.071 13.2 0.0 0.09 12.9 0.0 1.2 1 0 0 1 1 1 0 Podoplanin DUF4690 PF15756.5 EST48890.1 - 0.18 12.4 0.5 0.3 11.7 0.5 1.3 1 0 0 1 1 1 0 Small Novel Rich in Cartilage EGF_2 PF07974.13 EST48891.1 - 0.048 14.0 17.1 0.048 14.0 17.1 6.6 4 3 2 6 6 6 0 EGF-like domain Laminin_EGF PF00053.24 EST48891.1 - 2.1 8.5 78.5 0.26 11.4 18.2 4.9 1 1 3 4 4 4 0 Laminin EGF domain Myb_DNA-binding PF00249.31 EST48895.1 - 2.3e-06 27.7 0.3 3.8e-06 27.0 0.3 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST48895.1 - 0.00075 19.7 0.9 0.00094 19.4 0.9 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EST48895.1 - 0.001 18.9 0.5 0.0011 18.8 0.5 1.2 1 0 0 1 1 1 1 Myb DNA-binding like Tricorn_C1 PF14684.6 EST48895.1 - 0.059 13.4 0.1 0.089 12.9 0.1 1.3 1 0 0 1 1 1 0 Tricorn protease C1 domain DUF4096 PF13340.6 EST48895.1 - 0.061 13.6 0.1 0.095 12.9 0.1 1.4 1 1 0 1 1 1 0 Putative transposase of IS4/5 family (DUF4096) LAGLIDADG_1 PF00961.19 EST48896.1 - 0.002 19.1 1.2 2.5 9.1 0.1 2.8 2 0 0 2 2 2 2 LAGLIDADG endonuclease CNDH2_N PF06278.11 EST48897.1 - 9.8e-11 41.9 0.0 3.5e-10 40.1 0.0 2.0 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal NSP16 PF06460.12 EST48897.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Coronavirus NSP16 Rad21_Rec8_N PF04825.13 EST48897.1 - 0.13 12.5 0.0 0.33 11.1 0.0 1.7 1 0 0 1 1 1 0 N terminus of Rad21 / Rec8 like protein MBF2 PF15868.5 EST48898.1 - 0.063 13.8 0.1 0.14 12.7 0.1 1.6 1 1 0 1 1 1 0 Transcription activator MBF2 Myb_DNA-bind_6 PF13921.6 EST48900.1 - 5.1e-15 55.5 0.0 2.9e-09 37.0 0.0 2.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EST48900.1 - 7.4e-14 51.7 0.0 2.7e-07 30.6 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain HTH_32 PF13565.6 EST48900.1 - 0.0045 17.6 0.5 2.2 8.9 0.1 2.3 1 1 1 2 2 2 2 Homeodomain-like domain NDUF_C2 PF06374.11 EST48900.1 - 0.016 15.3 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) TPX2 PF06886.11 EST48902.1 - 1.8e-07 31.3 20.3 1.8e-07 31.3 20.3 2.1 2 0 0 2 2 2 1 Targeting protein for Xklp2 (TPX2) AAA_23 PF13476.6 EST48902.1 - 0.16 12.5 6.3 0.2 12.1 6.3 1.1 1 0 0 1 1 1 0 AAA domain Cas_GSU0054 PF09609.10 EST48905.1 - 0.097 11.4 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein, GSU0054 family (Cas_GSU0054) EGF PF00008.27 EST48907.1 - 0.0019 18.5 3.1 0.0019 18.5 3.1 13.5 13 3 0 13 13 13 5 EGF-like domain EGF_2 PF07974.13 EST48907.1 - 0.0032 17.8 12.4 0.0032 17.8 12.4 12.6 11 4 2 13 13 13 7 EGF-like domain Phage_holin_3_6 PF07332.11 EST48907.1 - 0.053 13.6 0.3 0.084 12.9 0.3 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Syndecan PF01034.20 EST48907.1 - 0.075 13.0 0.4 0.13 12.2 0.4 1.3 1 0 0 1 1 1 0 Syndecan domain Bacteriocin_IIc PF10439.9 EST48907.1 - 2.4 8.4 6.9 0.38 10.9 1.7 2.2 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Laminin_EGF PF00053.24 EST48907.1 - 5.4 7.2 165.9 0.076 13.2 11.2 9.7 4 3 4 8 8 8 0 Laminin EGF domain PGM_PMM_I PF02878.16 EST48909.1 - 3.7e-32 110.9 0.0 6.6e-32 110.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EST48909.1 - 3.8e-14 52.8 0.1 7.3e-14 51.9 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EST48909.1 - 8.9e-14 52.0 0.1 1.9e-13 50.9 0.1 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EST48909.1 - 6.5e-06 26.2 0.0 1.7e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Actino_peptide PF14408.6 EST48909.1 - 0.19 11.8 0.2 3 8.0 0.0 2.2 2 0 0 2 2 2 0 Ribosomally synthesised peptide in actinomycetes PGM_PMM_IV PF00408.20 EST48910.1 - 7.4e-06 26.1 0.0 8.5e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain CBM_20 PF00686.19 EST48910.1 - 0.017 15.0 0.6 0.019 14.8 0.6 1.1 1 0 0 1 1 1 0 Starch binding domain ParD_antitoxin PF03693.14 EST48913.1 - 0.16 12.4 0.0 0.18 12.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH EAP30 PF04157.16 EST48916.1 - 1.2e-05 24.7 2.2 4e-05 23.0 2.1 1.8 1 1 0 1 1 1 1 EAP30/Vps36 family DUF2857 PF11198.8 EST48916.1 - 0.098 12.4 0.7 1.3 8.8 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2857) YjbE PF11106.8 EST48917.1 - 0.028 14.6 0.7 0.057 13.6 0.7 1.4 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE Beta_elim_lyase PF01212.21 EST48919.1 - 1.3e-54 185.5 0.0 1.7e-54 185.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 EST48919.1 - 0.064 11.9 0.0 0.098 11.3 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Aminotran_1_2 PF00155.21 EST48919.1 - 0.16 11.1 0.0 1.7 7.7 0.0 2.4 3 0 0 3 3 3 0 Aminotransferase class I and II GATA-N PF05349.12 EST48921.1 - 0.072 13.4 0.0 0.076 13.3 0.0 1.1 1 0 0 1 1 1 0 GATA-type transcription activator, N-terminal GATA-N PF05349.12 EST48924.1 - 0.072 13.4 0.0 0.076 13.3 0.0 1.1 1 0 0 1 1 1 0 GATA-type transcription activator, N-terminal Beta_elim_lyase PF01212.21 EST48926.1 - 1.3e-54 185.5 0.0 1.7e-54 185.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 EST48926.1 - 0.064 11.9 0.0 0.098 11.3 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Aminotran_1_2 PF00155.21 EST48926.1 - 0.16 11.1 0.0 1.7 7.7 0.0 2.4 3 0 0 3 3 3 0 Aminotransferase class I and II Thioredoxin_9 PF14595.6 EST48927.1 - 4.9e-12 45.8 0.0 5.9e-12 45.5 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin PF00085.20 EST48927.1 - 2.3e-10 40.4 0.1 2.6e-10 40.2 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EST48927.1 - 3.2e-05 24.2 0.0 0.054 13.8 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EST48927.1 - 0.00042 20.7 0.0 0.00067 20.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EST48927.1 - 0.0031 17.7 0.5 0.0073 16.5 0.5 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.6 EST48927.1 - 0.0035 17.4 0.1 0.0049 16.9 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin domain DUF953 PF06110.11 EST48927.1 - 0.0049 16.5 0.1 0.0067 16.0 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) HyaE PF07449.11 EST48927.1 - 0.011 15.7 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.24 EST48927.1 - 0.049 13.9 0.1 0.11 12.8 0.1 1.6 1 1 1 2 2 2 0 Glutaredoxin TraF PF13728.6 EST48927.1 - 0.052 13.4 0.0 0.063 13.1 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_5 PF13743.6 EST48927.1 - 0.067 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin QSOX_Trx1 PF18108.1 EST48927.1 - 0.13 12.4 0.0 0.19 12.0 0.0 1.2 1 0 0 1 1 1 0 QSOX Trx-like domain EAP30 PF04157.16 EST48929.1 - 1.2e-05 24.8 2.1 3.9e-05 23.0 2.1 1.8 1 1 0 1 1 1 1 EAP30/Vps36 family DUF2857 PF11198.8 EST48929.1 - 0.031 14.1 0.7 0.19 11.5 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2857) HlyE PF06109.13 EST48932.1 - 0.032 13.5 0.5 0.035 13.4 0.5 1.2 1 0 0 1 1 1 0 Haemolysin E (HlyE) DUF2340 PF10209.9 EST48932.1 - 0.071 13.6 1.7 1.9 9.0 0.1 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2340) Myb_DNA-binding PF00249.31 EST48933.1 - 3e-07 30.5 0.3 4e-07 30.1 0.3 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST48933.1 - 7.8e-06 26.1 0.3 1e-05 25.6 0.3 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EST48933.1 - 0.0016 18.6 0.3 0.0023 18.1 0.3 1.3 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Corona_NS4 PF03905.13 EST48937.1 - 0.038 14.0 0.0 0.094 12.7 0.0 1.6 1 0 0 1 1 1 0 Coronavirus non-structural protein NS4 RRM_3 PF08777.11 EST48938.1 - 1.1e-15 57.6 0.1 2.2e-15 56.5 0.1 1.5 1 0 0 1 1 1 1 RNA binding motif RRM_1 PF00076.22 EST48938.1 - 0.00033 20.4 0.1 0.00072 19.3 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Met_10 PF02475.16 EST48939.1 - 0.017 14.9 0.1 0.019 14.7 0.1 1.0 1 0 0 1 1 1 0 Met-10+ like-protein PIG-L PF02585.17 EST48941.1 - 4.2e-11 43.6 0.1 1.6e-09 38.5 0.0 2.9 3 0 0 3 3 3 1 GlcNAc-PI de-N-acetylase PRK PF00485.18 EST48942.1 - 1.5e-16 60.8 0.0 1.7e-15 57.3 0.0 2.4 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 EST48942.1 - 0.085 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 EST48943.1 - 1.6e-16 60.6 0.0 2e-15 57.0 0.0 2.5 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 EST48943.1 - 0.089 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain NIF PF03031.18 EST48945.1 - 2.6e-12 46.8 2.0 8.7e-12 45.1 0.2 2.5 1 1 1 2 2 2 2 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.7 EST48945.1 - 0.0022 17.9 0.1 0.025 14.5 0.0 2.5 3 0 0 3 3 3 1 twin BRCT domain BRCT_2 PF16589.5 EST48945.1 - 0.032 14.6 2.4 0.21 12.0 2.4 2.4 1 1 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EST48945.1 - 0.56 10.6 10.0 0.064 13.6 1.3 3.5 3 1 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain Myb_DNA-binding PF00249.31 EST48946.1 - 3.1e-06 27.3 0.2 4e-06 26.9 0.2 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST48946.1 - 8.1e-06 26.0 0.2 1.1e-05 25.6 0.2 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EST48946.1 - 0.0031 17.7 0.2 0.0044 17.2 0.2 1.3 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 SmpA_OmlA PF04355.13 EST48946.1 - 0.35 10.7 3.2 2.8 7.8 1.3 2.6 2 1 0 2 2 2 0 SmpA / OmlA family DUF4138 PF13595.6 EST48949.1 - 0.024 13.9 0.2 0.028 13.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4138) Thioredoxin PF00085.20 EST48951.1 - 6.2e-09 35.8 0.0 6.8e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EST48951.1 - 8.2e-09 35.7 0.1 0.0014 18.9 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EST48951.1 - 1.2e-05 25.8 0.0 1.6e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 EST48951.1 - 1.2e-05 25.1 0.0 1.6e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 EST48951.1 - 0.0034 17.5 0.0 0.0056 16.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like HMG_CoA_synt_C PF08540.10 EST48951.1 - 0.017 14.7 0.1 0.022 14.4 0.1 1.1 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A synthase C terminal Thioredoxin_3 PF13192.6 EST48951.1 - 0.089 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain Peptidase_C1 PF00112.23 EST48952.1 - 2.7e-58 197.7 2.5 3.2e-58 197.4 2.5 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EST48952.1 - 7.6e-05 21.7 3.9 0.0056 15.5 0.9 2.1 2 0 0 2 2 2 2 Peptidase C1-like family LBP_BPI_CETP PF01273.25 EST48953.1 - 0.0017 18.0 3.0 0.0017 18.0 3.0 1.7 2 0 0 2 2 2 1 LBP / BPI / CETP family, N-terminal domain Aa_trans PF01490.18 EST48954.1 - 1.2e-38 132.9 35.0 1.2e-38 132.9 35.0 1.5 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EST48954.1 - 2.8e-08 33.2 33.0 1.9e-07 30.5 33.0 2.3 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family Apolipoprotein PF01442.18 EST48956.1 - 0.07 13.0 0.2 0.08 12.8 0.2 1.0 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain TcpQ PF10671.9 EST48956.1 - 0.16 12.1 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Toxin co-regulated pilus biosynthesis protein Q MPS2 PF17060.5 EST48958.1 - 0.15 11.3 6.0 0.21 10.8 6.0 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 Sec2p PF06428.11 EST48958.1 - 2.2 8.3 15.6 2.2 8.3 3.2 2.8 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p DUF4165 PF13752.6 EST48959.1 - 0.17 11.9 0.0 0.18 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4165) Metal_CEHH PF14455.6 EST48960.1 - 0.071 12.7 0.0 0.078 12.6 0.0 1.1 1 0 0 1 1 1 0 Predicted metal binding domain WD40 PF00400.32 EST48961.1 - 4.2e-06 27.4 5.5 1.3 10.0 0.1 5.5 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EST48961.1 - 0.00019 21.7 0.0 6.2 7.2 0.0 3.4 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EST48961.1 - 0.047 13.3 0.0 6.5 6.3 0.0 2.9 1 1 2 3 3 3 0 PQQ-like domain DUF3822 PF12864.7 EST48961.1 - 0.061 12.5 0.0 0.096 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3822) tRNA-synt_His PF13393.6 EST48962.1 - 0.028 13.7 0.3 0.033 13.5 0.3 1.0 1 0 0 1 1 1 0 Histidyl-tRNA synthetase AAA_12 PF13087.6 EST48963.1 - 1.1e-55 188.4 0.5 3e-55 187.0 0.5 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EST48963.1 - 6.5e-31 108.1 0.7 2.1e-28 99.8 0.7 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EST48963.1 - 3.7e-10 40.3 0.0 1.3e-09 38.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain UPF1_Zn_bind PF09416.10 EST48963.1 - 1.7e-09 37.8 6.5 7.5e-09 35.7 6.5 2.2 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) Viral_helicase1 PF01443.18 EST48963.1 - 2.6e-07 30.6 0.0 6.4e-05 22.8 0.0 3.6 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 EST48963.1 - 2.5e-06 27.3 0.0 3.9e-05 23.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EST48963.1 - 0.018 15.0 0.4 0.091 12.8 0.1 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DEAD PF00270.29 EST48963.1 - 0.02 14.7 3.3 1.3 8.8 0.7 3.7 3 1 0 3 3 3 0 DEAD/DEAH box helicase zf-UBP PF02148.19 EST48963.1 - 1.1 9.6 6.6 3.8 7.9 6.6 1.9 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein AAA PF00004.29 EST48965.1 - 6.2e-14 52.6 0.1 6.9e-12 45.9 0.1 3.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EST48965.1 - 0.0008 19.8 0.0 0.0067 16.8 0.0 2.6 2 0 0 2 2 1 1 AAA ATPase domain RuvB_N PF05496.12 EST48965.1 - 0.0015 18.3 0.0 0.0047 16.7 0.0 1.9 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 EST48965.1 - 0.0022 17.8 0.0 0.0091 15.8 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein ABC_tran PF00005.27 EST48965.1 - 0.0036 17.8 0.3 0.041 14.4 0.0 2.9 3 0 0 3 3 2 1 ABC transporter Mg_chelatase PF01078.21 EST48965.1 - 0.0042 16.5 0.0 0.01 15.3 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 EST48965.1 - 0.006 16.9 0.0 0.087 13.1 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EST48965.1 - 0.008 16.7 0.1 0.042 14.4 0.0 2.4 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 EST48965.1 - 0.011 15.9 0.0 0.04 14.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EST48965.1 - 0.015 14.6 0.1 0.045 13.0 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.6 EST48965.1 - 0.02 14.6 0.2 0.1 12.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 EST48965.1 - 0.023 13.9 3.6 0.088 12.0 0.1 2.4 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_5 PF07728.14 EST48965.1 - 0.023 14.7 0.1 0.062 13.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 EST48965.1 - 0.031 14.2 0.1 0.068 13.1 0.1 1.6 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 EST48965.1 - 0.036 14.5 0.1 0.61 10.5 0.0 3.0 3 0 0 3 3 2 0 RNA helicase IQ PF00612.27 EST48965.1 - 0.046 13.5 5.1 0.11 12.3 1.4 2.8 2 0 0 2 2 2 0 IQ calmodulin-binding motif SKI PF01202.22 EST48965.1 - 0.085 13.0 0.3 0.49 10.5 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase Flavodoxin_1 PF00258.25 EST48966.1 - 9.9e-05 22.6 0.0 0.00018 21.8 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin Lactamase_B_2 PF12706.7 EST48966.1 - 0.00013 21.6 0.1 0.00074 19.1 0.0 2.0 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Flavodoxin_5 PF12724.7 EST48966.1 - 0.00026 21.3 0.0 0.00047 20.4 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin domain Peptidase_C1 PF00112.23 EST48967.1 - 1.3e-38 133.3 0.7 2.7e-38 132.2 0.7 1.5 1 0 0 1 1 1 1 Papain family cysteine protease CathepsinC_exc PF08773.11 EST48967.1 - 2.2e-18 66.7 1.6 3.7e-18 66.0 1.6 1.4 1 0 0 1 1 1 1 Cathepsin C exclusion domain GH43_C PF16369.5 EST48967.1 - 0.035 14.7 0.2 0.097 13.3 0.2 1.7 1 0 0 1 1 1 0 C-terminal lipocalin-like domain Peptidase_C1_2 PF03051.15 EST48967.1 - 0.054 12.3 0.1 0.091 11.5 0.1 1.3 1 0 0 1 1 1 0 Peptidase C1-like family SCIMP PF15050.6 EST48968.1 - 0.028 14.9 0.4 0.034 14.6 0.4 1.2 1 0 0 1 1 1 0 SCIMP protein DUF5423 PF17461.2 EST48968.1 - 0.041 12.7 2.0 0.044 12.6 2.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5423) DUF2892 PF11127.8 EST48968.1 - 0.057 13.5 0.9 0.072 13.1 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) TRAM_LAG1_CLN8 PF03798.16 EST48970.1 - 2.2e-26 92.8 20.4 2.9e-26 92.4 20.4 1.1 1 0 0 1 1 1 1 TLC domain Ras PF00071.22 EST48973.1 - 5.8e-60 201.6 0.6 8.2e-60 201.1 0.6 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EST48973.1 - 5.6e-34 116.9 0.4 1e-33 116.1 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EST48973.1 - 6.1e-14 51.9 0.0 8.9e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EST48973.1 - 1.8e-05 24.8 0.0 3.9e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EST48973.1 - 0.00022 20.8 0.0 0.0014 18.3 0.0 2.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EST48973.1 - 0.0011 18.3 0.0 0.002 17.5 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EST48973.1 - 0.02 14.8 0.1 8.9 6.2 0.0 2.7 1 1 2 3 3 3 0 RsgA GTPase DUF313 PF03754.13 EST48975.1 - 0.39 11.0 4.4 0.36 11.1 3.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF313) DNA_pol_D_N PF18018.1 EST48975.1 - 1 9.4 6.0 3.5 7.8 0.3 2.5 2 1 0 2 2 2 0 DNA polymerase delta subunit OB-fold domain YbjQ_1 PF01906.17 EST48975.1 - 1.7 9.4 3.7 0.64 10.7 0.2 2.0 2 0 0 2 2 2 0 Putative heavy-metal-binding Cpn60_TCP1 PF00118.24 EST48976.1 - 8.4e-149 496.3 2.6 9.5e-149 496.2 2.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF799 PF05643.11 EST48976.1 - 0.047 13.3 0.0 0.094 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative bacterial lipoprotein (DUF799) Pox_A3L PF05288.11 EST48977.1 - 9.1 6.4 9.3 15 5.6 1.1 2.5 2 0 0 2 2 2 0 Poxvirus A3L Protein Spec3 PF15795.5 EST48978.1 - 0.72 10.4 9.4 5.3 7.6 7.0 2.3 1 1 1 2 2 2 0 Ectodermal ciliogenesis protein Podoplanin PF05808.11 EST48979.1 - 0.0013 18.8 2.2 0.0013 18.8 2.2 1.6 2 0 0 2 2 2 1 Podoplanin TPPK_C PF12555.8 EST48979.1 - 0.0027 17.7 0.3 0.0044 17.0 0.3 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphokinase C terminal VSP PF03302.13 EST48981.1 - 0.0071 15.3 27.2 0.0071 15.3 27.2 2.6 1 1 2 3 3 3 2 Giardia variant-specific surface protein VSP PF03302.13 EST48982.1 - 0.035 13.0 121.3 0.096 11.5 35.9 6.1 1 1 5 6 6 6 0 Giardia variant-specific surface protein MatE PF01554.18 EST48984.1 - 7.6e-18 64.7 12.2 7.6e-18 64.7 12.2 2.1 2 0 0 2 2 2 1 MatE Polysacc_synt_C PF14667.6 EST48984.1 - 0.00042 20.4 5.3 0.00042 20.4 5.3 2.9 3 1 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain YMF19 PF02326.15 EST48984.1 - 1.5 9.7 6.0 20 6.0 0.1 3.3 3 0 0 3 3 3 0 Plant ATP synthase F0 TraL PF07178.11 EST48986.1 - 0.0035 17.8 0.1 0.0047 17.4 0.1 1.1 1 0 0 1 1 1 1 TraL protein DUF4064 PF13273.6 EST48986.1 - 0.0043 17.3 0.1 0.0053 17.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) DUF515 PF04415.12 EST48986.1 - 0.0047 15.4 1.8 0.0054 15.2 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF515) Chordopox_A13L PF05961.11 EST48986.1 - 0.0074 16.5 0.1 0.014 15.6 0.1 1.6 1 0 0 1 1 1 1 Chordopoxvirus A13L protein Myc_target_1 PF15179.6 EST48986.1 - 0.04 13.8 0.0 0.045 13.7 0.0 1.1 1 0 0 1 1 1 0 Myc target protein 1 DUF1043 PF06295.12 EST48986.1 - 0.043 13.8 0.5 0.087 12.8 0.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) Saf_2TM PF18303.1 EST48986.1 - 0.049 13.2 0.1 0.055 13.1 0.1 1.1 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain OAD_gamma PF04277.13 EST48986.1 - 0.18 12.4 1.6 0.25 12.0 1.6 1.3 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain ETRAMP PF09716.10 EST48986.1 - 1.5 8.9 7.1 3.7 7.7 7.1 1.8 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) CYYR1 PF10873.8 EST48986.1 - 3.2 8.2 6.1 4.3 7.8 6.1 1.3 1 1 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Nop52 PF05997.12 EST48987.1 - 5.3e-23 82.0 0.9 8.7e-23 81.2 0.9 1.3 1 0 0 1 1 1 1 Nucleolar protein,Nop52 DUF3276 PF11680.8 EST48987.1 - 0.1 12.7 2.0 1.1 9.4 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3276) ABC_tran PF00005.27 EST48988.1 - 3.5e-34 118.3 0.2 1.4e-17 64.5 0.0 2.8 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EST48988.1 - 1.1e-14 55.0 1.8 0.0058 16.5 0.1 4.2 2 2 2 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EST48988.1 - 3.1e-13 49.7 4.7 8.2e-06 25.4 0.2 3.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain RLI PF04068.15 EST48988.1 - 4.6e-08 32.8 3.7 4.6e-08 32.8 3.7 2.3 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_23 PF13476.6 EST48988.1 - 7.4e-08 33.1 6.4 0.004 17.7 0.1 2.6 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EST48988.1 - 5.4e-07 29.3 0.4 0.035 13.9 0.5 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain Fer4 PF00037.27 EST48988.1 - 6.8e-07 28.8 3.8 6.8e-07 28.8 3.8 3.1 3 0 0 3 3 3 1 4Fe-4S binding domain AAA_16 PF13191.6 EST48988.1 - 1.9e-06 28.4 0.0 0.1 12.9 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EST48988.1 - 7.3e-06 26.3 0.2 0.052 13.8 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA PF00004.29 EST48988.1 - 2e-05 25.1 0.0 0.2 12.0 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EST48988.1 - 3.3e-05 23.9 0.2 0.45 10.4 0.1 3.3 3 1 1 4 4 3 2 RsgA GTPase NACHT PF05729.12 EST48988.1 - 3.4e-05 23.8 0.1 0.1 12.5 0.0 3.0 3 0 0 3 3 2 2 NACHT domain RNA_helicase PF00910.22 EST48988.1 - 6.7e-05 23.2 0.1 0.29 11.5 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Fer4_2 PF12797.7 EST48988.1 - 8e-05 22.5 11.7 0.0037 17.3 1.5 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Rad17 PF03215.15 EST48988.1 - 9.8e-05 22.3 0.3 0.32 10.9 0.0 2.7 2 1 0 2 2 2 2 Rad17 P-loop domain Fer4_6 PF12837.7 EST48988.1 - 0.00032 20.6 3.6 0.00032 20.6 3.6 2.8 3 0 0 3 3 2 1 4Fe-4S binding domain AAA_24 PF13479.6 EST48988.1 - 0.00037 20.3 0.3 0.08 12.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain Fer4_21 PF14697.6 EST48988.1 - 0.00054 20.0 12.0 0.00054 20.0 12.0 2.0 2 0 0 2 2 1 1 4Fe-4S dicluster domain AAA_15 PF13175.6 EST48988.1 - 0.00057 19.7 11.8 0.02 14.6 1.6 3.9 3 2 1 5 5 4 2 AAA ATPase domain MMR_HSR1 PF01926.23 EST48988.1 - 0.00066 19.7 0.3 1.8 8.7 0.1 3.2 2 1 0 2 2 2 2 50S ribosome-binding GTPase Fer4_7 PF12838.7 EST48988.1 - 0.00079 20.0 12.3 0.0066 17.0 12.7 2.3 1 1 1 2 2 2 1 4Fe-4S dicluster domain AAA_33 PF13671.6 EST48988.1 - 0.00097 19.3 0.0 0.84 9.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EST48988.1 - 0.001 18.8 0.1 2.1 8.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain DUF815 PF05673.13 EST48988.1 - 0.001 18.3 0.0 0.23 10.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) TsaE PF02367.17 EST48988.1 - 0.0013 18.8 0.1 0.44 10.5 0.1 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 EST48988.1 - 0.0013 18.8 0.1 1.1 9.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ATPase PF06745.13 EST48988.1 - 0.0014 18.0 0.9 0.06 12.7 0.5 3.2 4 0 0 4 4 4 1 KaiC AAA_14 PF13173.6 EST48988.1 - 0.0019 18.2 0.4 0.77 9.8 0.2 2.8 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EST48988.1 - 0.0024 17.4 0.1 2.7 7.5 0.1 2.7 2 0 0 2 2 2 1 P-loop containing dynein motor region Fer4_16 PF13484.6 EST48988.1 - 0.0037 18.1 0.2 0.0037 18.1 0.2 3.3 4 0 0 4 4 2 1 4Fe-4S double cluster binding domain Septin PF00735.18 EST48988.1 - 0.0059 15.9 0.2 0.88 8.8 0.0 2.3 2 0 0 2 2 2 1 Septin VirE PF05272.11 EST48988.1 - 0.0062 16.3 1.1 2.4 7.8 0.0 3.3 2 1 1 3 3 3 1 Virulence-associated protein E Fer4_10 PF13237.6 EST48988.1 - 0.0076 16.3 2.1 0.0076 16.3 2.1 2.7 2 1 1 3 3 2 2 4Fe-4S dicluster domain Sigma54_activat PF00158.26 EST48988.1 - 0.012 15.3 0.1 0.4 10.4 0.1 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.18 EST48988.1 - 0.015 14.7 0.5 1.2 8.4 0.2 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Fer4_9 PF13187.6 EST48988.1 - 0.017 15.3 12.9 0.017 15.3 12.9 1.9 2 0 0 2 2 1 0 4Fe-4S dicluster domain Sigma54_activ_2 PF14532.6 EST48988.1 - 0.017 15.2 1.6 7.4 6.7 0.1 3.5 2 2 1 3 3 3 0 Sigma-54 interaction domain DUF413 PF04219.12 EST48988.1 - 0.021 14.9 0.1 0.068 13.2 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function, DUF AAA_18 PF13238.6 EST48988.1 - 0.025 15.1 0.1 13 6.3 0.1 2.8 2 1 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EST48988.1 - 0.037 14.3 0.0 14 6.0 0.0 2.6 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 EST48988.1 - 0.055 13.6 6.9 1.3 9.0 0.3 3.5 3 1 0 4 4 4 0 Helicase HerA, central domain Roc PF08477.13 EST48988.1 - 0.072 13.3 0.2 14 6.0 0.1 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 EST48988.1 - 0.08 12.8 2.2 18 5.2 0.6 3.4 3 0 0 3 3 3 0 NTPase AAA_27 PF13514.6 EST48988.1 - 0.11 12.1 0.1 5 6.6 0.1 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EST48988.1 - 0.12 11.5 0.4 14 4.8 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain MeaB PF03308.16 EST48988.1 - 0.13 11.2 0.4 1.3 7.9 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Rad51 PF08423.11 EST48988.1 - 0.16 11.2 0.3 0.69 9.1 0.1 2.0 2 0 0 2 2 2 0 Rad51 AAA_28 PF13521.6 EST48988.1 - 0.22 11.7 0.3 15 5.8 0.1 3.0 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 EST48988.1 - 0.24 11.7 1.5 18 5.7 0.3 3.0 3 0 0 3 3 2 0 AAA domain CHIP_TPR_N PF18391.1 EST48988.1 - 2 9.2 5.3 2.6 8.9 0.7 2.4 2 0 0 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain Fer4_3 PF12798.7 EST48988.1 - 3.6 8.8 15.0 0.4 11.7 3.2 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain zf-CCCH_7 PF18586.1 EST48989.1 - 0.15 12.4 0.8 0.36 11.2 0.1 1.9 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 DUF4006 PF13179.6 EST48991.1 - 0.07 13.1 0.1 0.17 11.8 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF4006) Inj_translocase PF16928.5 EST48993.1 - 1.2 8.5 8.0 2.5 7.5 4.7 2.3 1 1 1 2 2 2 0 DNA/protein translocase of phage P22 injectosome TGT_C2 PF14810.6 EST48994.1 - 0.16 12.1 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Patch-forming domain C2 of tRNA-guanine transglycosylase POR_N PF01855.19 EST48995.1 - 1.1e-38 133.3 0.3 2.5e-38 132.1 0.3 1.6 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg TPP_enzyme_C PF02775.21 EST48995.1 - 1.3e-10 41.3 0.0 4.7e-10 39.5 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4_16 PF13484.6 EST48995.1 - 4.1e-10 40.4 25.5 1.1e-07 32.7 12.6 3.2 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_7 PF12838.7 EST48995.1 - 7.7e-09 36.0 11.7 7.7e-09 36.0 11.7 2.5 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4 PF00037.27 EST48995.1 - 2e-08 33.7 25.0 2e-05 24.2 8.1 3.1 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_9 PF13187.6 EST48995.1 - 3.1e-07 30.5 16.1 2.8e-06 27.4 14.1 2.8 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_21 PF14697.6 EST48995.1 - 6.3e-07 29.4 13.5 6.3e-07 29.4 13.5 2.5 2 1 0 2 2 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 EST48995.1 - 1.7e-06 28.0 16.1 7.4e-06 26.0 14.0 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 EST48995.1 - 2.5e-06 27.3 24.7 4.6e-05 23.3 7.8 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_8 PF13183.6 EST48995.1 - 1.3e-05 25.6 8.9 1.3e-05 25.6 8.9 2.0 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 EST48995.1 - 2.3e-05 24.2 20.0 0.00025 21.0 2.6 3.1 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_17 PF13534.6 EST48995.1 - 0.00016 22.2 10.7 0.00016 22.2 10.7 2.6 1 1 2 3 3 3 3 4Fe-4S dicluster domain PFOR_II PF17147.4 EST48995.1 - 0.00016 21.9 0.0 0.00034 20.9 0.0 1.6 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II POR PF01558.18 EST48995.1 - 0.00064 19.8 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Fer4_4 PF12800.7 EST48995.1 - 0.0016 18.8 2.9 0.0016 18.8 2.9 3.3 4 0 0 4 4 3 1 4Fe-4S binding domain Fer4_18 PF13746.6 EST48995.1 - 0.014 15.6 10.1 0.52 10.5 1.6 2.6 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 EST48995.1 - 0.094 13.7 23.2 0.21 12.6 5.0 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_15 PF13459.6 EST48995.1 - 0.28 11.9 8.8 36 5.2 3.7 3.6 3 0 0 3 3 3 0 4Fe-4S single cluster domain Fer4_22 PF17179.4 EST48995.1 - 0.76 10.7 21.1 2.1 9.2 2.6 3.8 2 1 2 4 4 3 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 EST48995.1 - 5.9 7.5 18.8 0.79 10.3 4.4 3.2 3 0 0 3 3 2 0 4Fe-4S single cluster domain of Ferredoxin I CO_dh PF02552.16 EST48997.1 - 0.17 11.6 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit DUF3290 PF11694.8 EST48998.1 - 1.5 8.8 7.1 0.2 11.6 1.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3290) DUF2070 PF09843.9 EST48998.1 - 1.7 6.8 11.7 2.4 6.3 11.7 1.2 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) UCH PF00443.29 EST48999.1 - 3e-14 53.1 10.1 1.5e-09 37.8 10.1 3.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EST48999.1 - 0.00018 21.2 1.6 0.00059 19.5 0.6 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase LRR_4 PF12799.7 EST48999.1 - 0.00093 19.5 7.2 0.011 16.1 1.1 4.2 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) zf_C2H2_13 PF18508.1 EST48999.1 - 0.003 17.1 1.0 0.15 11.7 0.0 2.5 2 0 0 2 2 2 1 Zinc finger domain LRR_8 PF13855.6 EST48999.1 - 0.0042 16.8 5.3 0.042 13.6 2.3 3.2 2 1 1 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 EST48999.1 - 0.22 11.6 1.4 6.1 7.2 0.0 3.6 4 0 0 4 4 4 0 Leucine Rich repeat Pox_MCEL PF03291.16 EST49000.1 - 4e-55 187.2 0.2 4.7e-55 187.0 0.2 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 EST49000.1 - 3.4e-08 34.1 0.0 7.5e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EST49000.1 - 1e-05 26.2 0.0 2.6e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EST49000.1 - 1e-05 25.4 0.0 2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EST49000.1 - 0.00011 22.7 0.0 0.00027 21.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EST49000.1 - 0.00052 19.9 0.0 0.00076 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain ParBc_2 PF08857.11 EST49000.1 - 0.008 16.3 0.1 3.2 7.8 0.0 2.4 2 0 0 2 2 2 2 Putative ParB-like nuclease Methyltransf_20 PF12147.8 EST49000.1 - 0.039 13.1 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase ACP_PD PF04336.12 EST49001.1 - 0.19 12.2 7.7 0.27 11.7 0.6 3.1 2 1 1 3 3 3 0 Acyl carrier protein phosphodiesterase Aminotran_1_2 PF00155.21 EST49002.1 - 2.6e-39 135.4 0.0 3.1e-39 135.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EST49002.1 - 0.00069 18.3 0.0 0.0011 17.6 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme TauE PF01925.19 EST49003.1 - 7.7e-22 78.1 27.1 2.4e-11 43.7 14.4 2.7 2 1 0 2 2 2 2 Sulfite exporter TauE/SafE VSP PF03302.13 EST49007.1 - 0.0043 16.0 16.4 0.0043 16.0 16.4 4.3 1 1 3 4 4 4 2 Giardia variant-specific surface protein zf-C2H2_11 PF16622.5 EST49007.1 - 0.01 15.6 0.2 0.01 15.6 0.2 7.6 9 0 0 9 9 9 0 zinc-finger C2H2-type FYVE_2 PF02318.16 EST49007.1 - 0.03 14.5 7.4 0.03 14.5 7.4 5.6 1 1 6 7 7 7 0 FYVE-type zinc finger DUF3930 PF13067.6 EST49008.1 - 0.064 13.5 0.0 0.092 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3930) Myb_DNA-binding PF00249.31 EST49010.1 - 1e-07 32.0 0.0 1.9e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST49010.1 - 7.9e-07 29.2 0.0 1.1e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Ribosomal_L7Ae PF01248.26 EST49012.1 - 7.8e-18 64.0 0.4 9.9e-18 63.7 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Laminin_II PF06009.12 EST49012.1 - 0.12 12.4 0.5 0.21 11.6 0.5 1.3 1 0 0 1 1 1 0 Laminin Domain II FBA_2 PF07735.17 EST49013.1 - 0.36 11.0 5.6 1.6 8.9 0.3 2.6 2 1 0 2 2 2 0 F-box associated Ribosomal_S4Pg PF11993.8 EST49014.1 - 0.017 15.2 5.0 0.045 13.8 5.0 1.7 1 0 0 1 1 1 0 Ribosomal S4P (gammaproteobacterial) DUF3835 PF12927.7 EST49014.1 - 0.2 12.5 1.1 0.37 11.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3835) HSP70 PF00012.20 EST49015.1 - 0.00071 17.9 0.1 0.001 17.4 0.1 1.3 1 0 0 1 1 1 1 Hsp70 protein MutL PF13941.6 EST49015.1 - 0.02 13.5 0.1 0.034 12.8 0.1 1.3 1 0 0 1 1 1 0 MutL protein MreB_Mbl PF06723.13 EST49015.1 - 0.18 10.6 0.1 0.25 10.1 0.1 1.2 1 0 0 1 1 1 0 MreB/Mbl protein FtsA PF14450.6 EST49015.1 - 0.31 11.5 1.0 0.72 10.3 1.0 1.8 1 1 0 1 1 1 0 Cell division protein FtsA SYCP2_ARLD PF18581.1 EST49018.1 - 0.052 13.6 1.9 0.2 11.6 0.5 2.3 1 1 1 2 2 2 0 Synaptonemal complex 2 armadillo-repeat-like domain SGL PF08450.12 EST49019.1 - 0.02 14.5 0.0 0.055 13.1 0.0 1.7 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region BBS2_Mid PF14783.6 EST49019.1 - 0.056 13.5 0.5 11 6.1 0.0 3.7 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region DUF2205 PF10224.9 EST49023.1 - 0.12 12.3 0.4 0.12 12.3 0.4 1.7 2 0 0 2 2 2 0 Short coiled-coil protein ADK PF00406.22 EST49026.1 - 4.2e-44 150.3 0.0 5.1e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EST49026.1 - 4.5e-26 91.9 0.0 8.2e-26 91.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EST49026.1 - 4.4e-05 23.7 0.0 0.00022 21.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EST49026.1 - 0.00047 20.7 0.0 0.0012 19.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 EST49026.1 - 0.0078 16.0 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Cytidylate kinase AAA PF00004.29 EST49026.1 - 0.013 16.0 0.0 0.021 15.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EST49026.1 - 0.018 14.4 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 EST49026.1 - 0.027 14.2 0.0 0.04 13.7 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Hydin_ADK PF17213.3 EST49026.1 - 0.027 14.7 0.0 0.38 11.0 0.0 2.5 2 1 1 3 3 3 0 Hydin Adenylate kinase-like domain Thymidylate_kin PF02223.17 EST49026.1 - 0.078 12.6 0.0 0.24 11.0 0.0 1.7 2 0 0 2 2 2 0 Thymidylate kinase HAD_2 PF13419.6 EST49027.1 - 5.3e-26 91.8 0.3 1.7e-25 90.1 0.3 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EST49027.1 - 1.4e-09 38.6 0.0 5.2e-09 36.7 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EST49027.1 - 3.6e-07 30.8 0.0 1.8e-06 28.5 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EST49027.1 - 0.00016 21.7 0.1 0.00079 19.5 0.1 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EST49027.1 - 0.00021 21.3 0.0 0.00055 19.9 0.0 1.6 1 1 0 1 1 1 1 HAD-hyrolase-like Hydrolase_3 PF08282.12 EST49027.1 - 0.00085 19.1 0.0 0.053 13.3 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Spc7 PF08317.11 EST49030.1 - 0.0069 15.3 12.9 0.01 14.8 12.9 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF244 PF03112.14 EST49030.1 - 0.033 14.0 2.3 0.053 13.4 2.1 1.4 1 1 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF Baculo_PEP_C PF04513.12 EST49030.1 - 0.056 13.5 9.7 0.17 12.0 7.8 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1854 PF08909.11 EST49030.1 - 0.074 12.9 4.5 0.1 12.4 3.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1854) Terminase_2 PF03592.16 EST49030.1 - 0.21 12.1 6.5 0.3 11.6 6.5 1.2 1 0 0 1 1 1 0 Terminase small subunit BPL_N PF09825.9 EST49030.1 - 0.23 10.5 5.6 0.26 10.3 5.6 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal AI-2E_transport PF01594.16 EST49030.1 - 0.49 9.5 2.9 0.51 9.4 2.9 1.2 1 0 0 1 1 1 0 AI-2E family transporter DUF1943 PF09172.11 EST49030.1 - 0.59 9.3 5.5 0.68 9.1 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Remorin_C PF03763.13 EST49030.1 - 1.8 8.5 9.1 0.85 9.5 2.8 2.3 1 1 1 2 2 2 0 Remorin, C-terminal region DUF4407 PF14362.6 EST49030.1 - 1.8 7.8 16.1 2.7 7.3 3.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF1896 PF08989.10 EST49031.1 - 0.046 13.8 0.1 0.089 12.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1896) NDK PF00334.19 EST49033.1 - 9.7e-40 135.7 0.0 5.4e-20 71.8 0.0 2.1 2 0 0 2 2 2 2 Nucleoside diphosphate kinase DUF1126 PF06565.12 EST49033.1 - 0.00067 19.4 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 DUF1126 PH-like domain SBDS_C PF09377.10 EST49033.1 - 0.099 12.7 0.1 16 5.5 0.0 2.4 2 0 0 2 2 2 0 SBDS protein C-terminal domain WD40 PF00400.32 EST49034.1 - 2.6e-22 78.7 7.6 0.04 14.8 0.0 10.7 11 1 0 11 11 11 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EST49034.1 - 4.4e-11 42.9 0.1 0.01 16.1 0.0 5.8 5 1 2 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EST49034.1 - 4.2e-07 29.6 21.4 0.06 12.7 0.0 6.4 3 2 1 5 5 5 3 WD40-like domain CNH PF00780.22 EST49034.1 - 0.0085 15.7 1.5 2 8.0 0.0 4.5 5 1 1 6 6 6 1 CNH domain Coatomer_WDAD PF04053.14 EST49034.1 - 0.016 14.3 0.3 0.27 10.2 0.1 2.6 2 0 0 2 2 2 0 Coatomer WD associated region PP2C PF00481.21 EST49036.1 - 2.1e-63 214.3 0.5 2.4e-63 214.2 0.5 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EST49036.1 - 9.9e-09 35.1 0.6 1.8e-08 34.3 0.6 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C KA1 PF02149.19 EST49040.1 - 0.044 13.6 0.2 13 5.6 0.0 3.2 3 0 0 3 3 3 0 Kinase associated domain 1 Collagen PF01391.18 EST49041.1 - 0.068 12.9 2.7 0.11 12.3 2.7 1.2 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Tir_receptor_C PF07489.11 EST49043.1 - 0.11 12.4 0.3 0.14 12.1 0.3 1.1 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus TPR_2 PF07719.17 EST49046.1 - 0.00079 19.4 0.0 0.03 14.4 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EST49046.1 - 0.0091 16.6 0.5 0.064 13.9 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EST49046.1 - 0.038 14.3 0.0 2.7 8.4 0.0 2.2 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EST49046.1 - 0.044 13.6 0.0 0.29 11.0 0.0 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EST49046.1 - 0.19 12.0 0.0 13 6.3 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Cyt-b5 PF00173.28 EST49047.1 - 9.1e-06 25.7 0.0 1.4e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pectinesterase PF01095.19 EST49049.1 - 0.02 13.6 1.6 0.031 13.0 1.6 1.2 1 0 0 1 1 1 0 Pectinesterase Glyco_tranf_2_3 PF13641.6 EST49050.1 - 0.0091 15.9 0.0 0.025 14.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Class_IIIsignal PF04021.12 EST49050.1 - 0.46 10.5 1.6 1.1 9.4 1.6 1.7 1 0 0 1 1 1 0 Class III signal peptide ALS2CR11 PF15729.5 EST49053.1 - 0.088 11.9 11.4 0.1 11.7 11.4 1.0 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 candidate 11 MIase PF02426.16 EST49053.1 - 4.8 7.4 6.6 3 8.1 0.6 2.6 2 1 0 2 2 2 0 Muconolactone delta-isomerase DUF4320 PF14208.6 EST49053.1 - 6 7.0 9.0 0.88 9.7 3.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4320) DUF1842 PF08896.10 EST49054.1 - 0.1 12.9 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1842) DUF2222 PF09984.9 EST49056.1 - 0.00092 19.1 0.4 0.003 17.5 0.4 1.8 1 0 0 1 1 1 1 Uncharacterised signal transduction histidine kinase domain (DUF2222) Uteroglobin PF01099.17 EST49056.1 - 0.031 14.6 0.3 0.94 9.9 0.0 3.1 2 0 0 2 2 2 0 Uteroglobin family Ribosomal_L6 PF00347.23 EST49064.1 - 3.5e-18 66.0 0.7 9.7e-12 45.4 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Peptidase_S30 PF01577.16 EST49064.1 - 0.084 12.5 1.9 19 4.7 0.1 2.9 2 1 1 3 3 3 0 Potyvirus P1 protease MNSV_P7B PF06692.11 EST49066.1 - 0.021 14.8 0.1 3.8 7.6 0.0 2.7 2 0 0 2 2 2 0 Melon necrotic spot virus P7B protein Ribosomal_L6 PF00347.23 EST49067.1 - 2.8e-12 47.1 0.0 3.3e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L6 Peptidase_S30 PF01577.16 EST49067.1 - 0.028 14.1 0.1 5.7 6.5 0.0 2.0 1 1 1 2 2 2 0 Potyvirus P1 protease FLgD_tudor PF13861.6 EST49067.1 - 0.062 13.5 0.1 0.36 11.1 0.1 1.9 1 1 0 1 1 1 0 FlgD Tudor-like domain TMEM154 PF15102.6 EST49069.1 - 0.02 14.8 1.4 0.048 13.6 1.4 1.5 1 0 0 1 1 1 0 TMEM154 protein family Y_phosphatase PF00102.27 EST49070.1 - 2.4e-16 60.0 2.0 1.1e-15 57.9 2.0 1.9 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 EST49070.1 - 2e-05 24.4 0.0 4.4e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 EST49070.1 - 0.016 14.9 0.1 0.033 13.8 0.1 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) DUF667 PF05018.13 EST49071.1 - 2.5e-84 281.6 0.7 2.8e-84 281.5 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) MPS-4 PF17523.2 EST49072.1 - 3.7 7.7 6.3 38 4.5 3.9 2.9 2 0 0 2 2 2 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 Glucosamine_iso PF01182.20 EST49073.1 - 1.8e-09 37.8 0.0 2.7e-09 37.3 0.0 1.3 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase UPF0004 PF00919.20 EST49076.1 - 0.033 14.3 0.1 0.064 13.3 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein family UPF0004 DUF512 PF04459.12 EST49076.1 - 0.049 12.9 0.0 0.058 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF512) zf-CHY PF05495.12 EST49077.1 - 6.5e-07 29.7 14.9 6.5e-07 29.7 14.9 3.3 3 2 0 3 3 3 1 CHY zinc finger EMC1_C PF07774.13 EST49078.1 - 0.0056 16.4 0.5 0.0089 15.7 0.5 1.3 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal DUF4303 PF14136.6 EST49079.1 - 0.17 11.6 0.0 0.17 11.6 0.0 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4303) Prp19 PF08606.11 EST49080.1 - 0.0094 15.9 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 Prp19/Pso4-like PepSY PF03413.19 EST49080.1 - 0.038 14.6 0.1 0.062 13.9 0.1 1.3 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain zf-CHY PF05495.12 EST49081.1 - 0.0011 19.4 11.8 0.0011 19.4 11.8 3.3 3 0 0 3 3 3 1 CHY zinc finger Par3_HAL_N_term PF12053.8 EST49081.1 - 0.64 10.3 5.3 3 8.1 0.2 3.6 3 0 0 3 3 3 0 N-terminal of Par3 and HAL proteins Polyketide_cyc PF03364.20 EST49081.1 - 0.97 9.6 2.9 13 6.0 0.3 2.6 2 1 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport Syntaxin-6_N PF09177.11 EST49085.1 - 3.6 8.2 6.3 2.9 8.5 0.8 2.9 4 0 0 4 4 4 0 Syntaxin 6, N-terminal ITI_HC_C PF06668.12 EST49086.1 - 0.049 13.3 0.4 0.12 12.0 0.4 1.6 1 0 0 1 1 1 0 Inter-alpha-trypsin inhibitor heavy chain C-terminus HigB-like_toxin PF05015.13 EST49086.1 - 0.6 10.5 6.7 0.45 11.0 0.3 3.4 3 0 0 3 3 3 0 RelE-like toxin of type II toxin-antitoxin system HigB FAP PF07174.11 EST49087.1 - 8.8e-05 22.1 3.6 0.00014 21.4 3.6 1.4 1 0 0 1 1 1 1 Fibronectin-attachment protein (FAP) VSP PF03302.13 EST49087.1 - 0.00026 20.0 52.7 0.00074 18.5 0.6 3.7 2 1 1 3 3 3 3 Giardia variant-specific surface protein DUF4366 PF14283.6 EST49087.1 - 0.092 12.8 2.1 0.12 12.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) DUF4748 PF15932.5 EST49087.1 - 0.34 10.7 1.7 0.67 9.7 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) DUF3042 PF11240.8 EST49087.1 - 2.4 8.3 5.0 4.2 7.5 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) Bacteriocin_IIc PF10439.9 EST49087.1 - 5.6 7.2 10.1 13 6.0 10.1 1.5 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Podoplanin PF05808.11 EST49087.1 - 6.4 6.9 6.6 1.3 9.1 0.2 2.4 2 1 0 2 2 2 0 Podoplanin VSP PF03302.13 EST49089.1 - 0.00048 19.1 78.8 0.00062 18.7 2.6 3.1 1 1 2 3 3 3 3 Giardia variant-specific surface protein FAP PF07174.11 EST49091.1 - 8.8e-05 22.1 3.6 0.00014 21.4 3.6 1.4 1 0 0 1 1 1 1 Fibronectin-attachment protein (FAP) VSP PF03302.13 EST49091.1 - 0.00026 20.0 52.7 0.00074 18.5 0.6 3.7 2 1 1 3 3 3 3 Giardia variant-specific surface protein DUF4366 PF14283.6 EST49091.1 - 0.092 12.8 2.1 0.12 12.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) DUF4748 PF15932.5 EST49091.1 - 0.34 10.7 1.7 0.67 9.7 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) DUF3042 PF11240.8 EST49091.1 - 2.4 8.3 5.0 4.2 7.5 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) Bacteriocin_IIc PF10439.9 EST49091.1 - 5.6 7.2 10.1 13 6.0 10.1 1.5 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Podoplanin PF05808.11 EST49091.1 - 6.4 6.9 6.6 1.3 9.1 0.2 2.4 2 1 0 2 2 2 0 Podoplanin Arrestin_C PF02752.22 EST49093.1 - 0.083 13.3 0.1 0.11 12.9 0.1 1.2 1 0 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain Glyco_hydro_1 PF00232.18 EST49098.1 - 0.019 13.4 0.9 0.022 13.2 0.9 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 zf-TFIIIC PF12660.7 EST49098.1 - 0.02 14.8 3.1 0.083 12.8 3.0 2.0 1 1 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex DUF4985 PF16373.5 EST49098.1 - 0.19 12.2 3.7 8 7.0 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function AlcCBM31 PF11606.8 EST49099.1 - 0.029 14.5 1.2 0.05 13.8 1.2 1.4 1 0 0 1 1 1 0 Family 31 carbohydrate binding protein Pribosyltran PF00156.27 EST49100.1 - 1e-07 31.6 0.0 1.4e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EST49100.1 - 3.4e-05 23.4 0.0 4.8e-05 22.9 0.0 1.3 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase WD40 PF00400.32 EST49101.1 - 7.8e-06 26.5 0.8 0.0077 17.1 0.1 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat Ubie_methyltran PF01209.18 EST49101.1 - 0.016 14.6 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PEPcase_2 PF14010.6 EST49103.1 - 0.076 11.5 4.6 0.023 13.2 1.1 1.7 1 1 0 1 1 1 0 Phosphoenolpyruvate carboxylase EFhand_Ca_insen PF08726.10 EST49103.1 - 0.24 11.5 2.1 0.22 11.6 0.3 1.8 2 0 0 2 2 2 0 Ca2+ insensitive EF hand Pribosyltran PF00156.27 EST49104.1 - 2.1e-07 30.6 0.0 3.1e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EST49104.1 - 5.8e-05 22.6 0.0 9.3e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Myb_DNA-binding PF00249.31 EST49106.1 - 2.1e-05 24.6 0.0 2.9e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST49106.1 - 0.00029 21.0 0.0 0.045 14.0 0.0 2.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EST49107.1 - 5.7e-05 23.2 0.0 0.00035 20.7 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST49107.1 - 0.00041 20.5 0.0 0.022 15.0 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EST49110.1 - 1.3e-06 28.5 0.0 1.4e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST49110.1 - 0.0038 17.4 0.0 0.0043 17.3 0.0 1.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain HTH_AsnC-type PF13404.6 EST49110.1 - 0.14 12.0 0.1 0.48 10.3 0.1 1.8 1 1 0 1 1 1 0 AsnC-type helix-turn-helix domain CK_II_beta PF01214.18 EST49111.1 - 0.019 14.8 0.4 0.023 14.5 0.4 1.2 1 0 0 1 1 1 0 Casein kinase II regulatory subunit DEDD_Tnp_IS110 PF01548.17 EST49111.1 - 0.093 12.6 2.6 0.29 11.0 0.5 2.1 2 0 0 2 2 2 0 Transposase Rbx_binding PF18113.1 EST49112.1 - 0.062 13.1 0.1 0.12 12.2 0.1 1.5 1 1 0 1 1 1 0 Rubredoxin binding C-terminal domain NUMOD3 PF07460.11 EST49112.1 - 0.077 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 NUMOD3 motif (2 copies) AAA_6 PF12774.7 EST49114.1 - 2.2e-81 273.4 0.1 9.5e-81 271.3 0.0 2.3 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EST49114.1 - 6.4e-49 167.1 11.3 6.4e-49 167.1 11.3 5.4 3 2 2 5 5 3 1 Dynein heavy chain, N-terminal region 2 MT PF12777.7 EST49114.1 - 2.4e-25 89.3 17.6 2.4e-25 89.3 17.6 2.5 3 0 0 3 3 3 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 EST49114.1 - 1.5e-18 67.1 0.0 2.5e-09 37.2 0.0 4.2 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_lid_11 PF18198.1 EST49114.1 - 1e-06 28.7 0.0 5.6e-06 26.3 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_7 PF12775.7 EST49114.1 - 2.7e-05 23.7 10.5 6.1e-05 22.6 0.0 4.0 5 0 0 5 5 5 2 P-loop containing dynein motor region Dynein_heavy PF03028.15 EST49114.1 - 0.00029 20.9 0.0 0.002 18.2 0.0 2.6 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain AAA_16 PF13191.6 EST49114.1 - 0.017 15.5 3.2 16 5.8 0.0 5.6 3 1 1 4 4 4 0 AAA ATPase domain AAA PF00004.29 EST49114.1 - 0.024 15.1 1.1 0.23 11.9 0.0 3.5 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) TFIIE_beta PF02186.15 EST49114.1 - 0.33 11.3 2.0 1.1 9.5 0.1 3.1 2 0 0 2 2 1 0 TFIIE beta subunit core domain DUF948 PF06103.11 EST49114.1 - 4 7.8 24.3 0.23 11.7 1.6 6.2 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF5370 PF17340.2 EST49115.1 - 0.24 11.3 3.7 0.16 11.9 1.0 2.1 2 1 0 2 2 2 0 Family of unknown function (DUF5370) HEAT PF02985.22 EST49119.1 - 0.013 15.7 11.9 0.64 10.4 0.3 5.7 7 0 0 7 7 7 0 HEAT repeat Kinesin PF00225.23 EST49121.1 - 2.2e-92 309.5 0.2 3.6e-92 308.9 0.2 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EST49121.1 - 6.2e-25 87.9 0.2 2e-24 86.3 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding SplA PF11132.8 EST49121.1 - 0.11 12.3 0.3 4.5 7.1 0.0 2.5 2 0 0 2 2 2 0 Transcriptional regulator protein (SplA) DUF465 PF04325.13 EST49121.1 - 0.65 10.1 7.2 7 6.8 3.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF465) Consortin_C PF15281.6 EST49123.1 - 0.039 13.9 0.0 0.06 13.3 0.0 1.3 1 0 0 1 1 1 0 Consortin C-terminus OATP PF03137.20 EST49123.1 - 0.32 9.2 5.3 1.1 7.5 0.4 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Tim54 PF11711.8 EST49123.1 - 0.57 8.9 3.7 0.8 8.4 3.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Menin PF05053.13 EST49123.1 - 2.3 6.5 4.2 3 6.1 4.2 1.1 1 0 0 1 1 1 0 Menin CCSAP PF15748.5 EST49123.1 - 6.5 6.8 14.7 8.8 6.4 14.7 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated PI3_PI4_kinase PF00454.27 EST49124.1 - 1.4e-42 146.2 1.4 4.6e-42 144.6 0.3 2.4 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 EST49124.1 - 7e-20 71.5 13.7 7e-20 71.5 13.7 2.4 3 0 0 3 3 3 1 FAT domain FATC PF02260.20 EST49124.1 - 1.3e-05 24.9 1.1 5.4e-05 22.9 0.3 2.5 2 0 0 2 2 2 1 FATC domain DUF3385 PF11865.8 EST49124.1 - 0.0053 16.7 24.4 0.031 14.2 12.8 5.9 4 1 0 4 4 4 1 Domain of unknown function (DUF3385) Dpoe2NT PF12213.8 EST49124.1 - 7.5 6.9 7.2 60 4.0 0.1 4.8 3 1 1 4 4 4 0 DNA polymerases epsilon N terminal MINDY_DUB PF04424.13 EST49125.1 - 0.057 13.4 0.9 0.2 11.7 0.9 1.9 1 0 0 1 1 1 0 MINDY deubiquitinase Orf78 PF06024.12 EST49125.1 - 2.3 8.6 10.1 13 6.2 0.6 2.9 2 0 0 2 2 2 0 Orf78 (ac78) Thioredoxin_4 PF13462.6 EST49128.1 - 1.8 8.7 4.8 0.61 10.2 1.7 1.8 1 1 1 2 2 2 0 Thioredoxin DUF3540 PF12059.8 EST49129.1 - 4.6 7.0 16.4 0.43 10.4 1.5 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3540) UPF0184 PF03670.13 EST49129.1 - 6.6 7.2 8.6 2.4 8.6 0.1 3.9 2 1 2 4 4 4 0 Uncharacterised protein family (UPF0184) Rad52_Rad22 PF04098.15 EST49131.1 - 6.3e-32 110.6 0.0 7.9e-32 110.3 0.0 1.0 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein DUF2798 PF11391.8 EST49132.1 - 0.045 13.8 0.7 0.13 12.3 0.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2798) YukC PF10140.9 EST49132.1 - 0.054 12.3 0.3 0.09 11.6 0.3 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC ABC_tran PF00005.27 EST49133.1 - 1.1e-19 71.3 0.0 1.9e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EST49133.1 - 5.9e-13 49.3 0.0 1.1e-06 28.7 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EST49133.1 - 1.8e-06 27.6 0.3 0.012 15.1 0.0 2.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EST49133.1 - 0.0027 18.0 0.1 0.0066 16.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EST49133.1 - 0.0037 17.7 0.0 0.0098 16.3 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EST49133.1 - 0.011 15.5 0.0 0.26 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EST49133.1 - 0.025 14.6 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EST49133.1 - 0.027 14.4 0.1 0.049 13.5 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 EST49133.1 - 0.033 13.9 0.1 0.061 13.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 EST49133.1 - 0.045 12.9 0.1 0.066 12.4 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain Viral_helicase1 PF01443.18 EST49133.1 - 0.051 13.3 0.1 3.6 7.2 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_13 PF13166.6 EST49133.1 - 0.06 12.0 0.0 0.071 11.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 EST49133.1 - 0.067 13.4 0.0 2.5 8.4 0.0 2.6 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit PduV-EutP PF10662.9 EST49133.1 - 0.086 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.6 EST49133.1 - 0.094 12.8 0.5 0.77 9.8 0.3 2.4 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EST49133.1 - 0.1 12.5 0.1 0.24 11.3 0.2 1.7 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 EST49133.1 - 0.13 12.5 0.0 0.17 12.0 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EST49133.1 - 0.13 12.8 0.0 0.55 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EST49133.1 - 0.15 12.4 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase MobB PF03205.14 EST49133.1 - 0.16 11.9 0.1 0.26 11.2 0.1 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.6 EST49133.1 - 0.16 12.3 0.0 0.39 11.1 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 EST49133.1 - 0.17 12.4 4.7 0.39 11.2 4.7 1.9 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EST49133.1 - 0.18 11.5 4.5 0.45 10.2 4.5 1.8 1 1 0 1 1 1 0 AAA ATPase domain IP_trans PF02121.18 EST49136.1 - 1.2e-05 25.1 2.3 0.0032 17.1 0.2 2.1 1 1 1 2 2 2 2 Phosphatidylinositol transfer protein NIF PF03031.18 EST49137.1 - 8e-41 139.4 1.9 8e-41 139.4 1.9 1.4 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase Hydrolase PF00702.26 EST49137.1 - 0.075 13.3 0.0 0.55 10.5 0.1 1.8 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase DUF3694 PF12473.8 EST49138.1 - 0.16 12.6 2.2 0.24 12.0 2.2 1.5 1 1 0 1 1 1 0 Kinesin protein ABC_tran PF00005.27 EST49140.1 - 3.2e-18 66.5 0.0 5.9e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EST49140.1 - 1.4e-12 48.1 0.0 1.1e-06 28.7 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EST49140.1 - 3.4e-06 26.7 0.2 0.013 14.9 0.0 2.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA PF00004.29 EST49140.1 - 0.0041 17.6 0.0 0.01 16.2 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EST49140.1 - 0.009 16.3 0.0 0.022 15.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EST49140.1 - 0.01 15.6 0.0 0.23 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EST49140.1 - 0.031 14.3 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EST49140.1 - 0.031 14.2 0.1 0.059 13.3 0.1 1.4 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 EST49140.1 - 0.037 13.2 0.0 0.058 12.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Viral_helicase1 PF01443.18 EST49140.1 - 0.058 13.1 0.1 3.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase SbcCD_C PF13558.6 EST49140.1 - 0.077 13.2 0.0 2.7 8.3 0.0 2.5 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 EST49140.1 - 0.08 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.9 EST49140.1 - 0.11 12.3 0.1 0.21 11.3 0.1 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_13 PF13166.6 EST49140.1 - 0.12 10.9 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EST49140.1 - 0.14 12.7 0.0 0.59 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EST49140.1 - 0.16 12.2 0.0 0.23 11.6 0.0 1.3 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EST49140.1 - 0.17 12.3 0.0 0.32 11.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_15 PF13175.6 EST49140.1 - 0.23 11.1 3.5 0.65 9.7 3.5 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 EST49140.1 - 0.78 10.2 4.6 0.29 11.6 1.1 1.8 1 1 0 2 2 2 0 AAA domain Ocnus PF05005.15 EST49141.1 - 0.13 12.4 0.1 0.37 11.0 0.0 1.8 2 0 0 2 2 2 0 Janus/Ocnus family (Ocnus) DUF2798 PF11391.8 EST49141.1 - 0.52 10.4 10.3 0.32 11.1 0.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2798) Tmemb_55A PF09788.9 EST49141.1 - 0.78 8.8 4.7 2 7.4 4.7 1.7 1 0 0 1 1 1 0 Transmembrane protein 55A YukC PF10140.9 EST49141.1 - 2.5 6.9 8.4 0.25 10.1 0.3 2.7 3 0 0 3 3 3 0 WXG100 protein secretion system (Wss), protein YukC Rad52_Rad22 PF04098.15 EST49142.1 - 6.3e-32 110.6 0.0 7.9e-32 110.3 0.0 1.0 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Nrap_D5 PF17406.2 EST49143.1 - 0.0081 15.9 1.0 1 9.1 0.2 2.8 2 0 0 2 2 2 2 Nrap protein PAP/OAS1-like domain 5 Fer4_5 PF12801.7 EST49145.1 - 0.25 11.3 3.8 0.58 10.1 0.2 3.3 2 0 0 2 2 2 0 4Fe-4S binding domain Pkinase PF00069.25 EST49146.1 - 1.1e-58 198.7 0.2 1.7e-58 198.0 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST49146.1 - 2.5e-38 131.9 0.0 3.6e-38 131.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EST49146.1 - 2.6e-06 27.0 0.1 9.1e-06 25.2 0.0 1.9 1 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EST49146.1 - 1.7e-05 23.8 0.0 3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EST49146.1 - 0.052 12.9 0.4 0.081 12.3 0.4 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Rieske_3 PF18465.1 EST49146.1 - 0.097 12.9 0.1 0.39 11.0 0.0 2.0 2 0 0 2 2 2 0 Rieske 3Fe-4S Pkinase PF00069.25 EST49147.1 - 1.1e-61 208.6 0.0 1.2e-61 208.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST49147.1 - 4.4e-27 95.0 0.0 5.7e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EST49147.1 - 0.0011 18.4 0.2 0.0042 16.5 0.0 1.9 1 1 0 1 1 1 1 Kinase-like B-block_TFIIIC PF04182.12 EST49147.1 - 0.018 15.2 0.2 0.055 13.6 0.2 1.8 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC Haspin_kinase PF12330.8 EST49147.1 - 0.03 13.3 0.1 0.044 12.7 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 EST49147.1 - 0.052 12.6 0.5 0.2 10.6 0.0 1.9 2 0 0 2 2 2 0 Seadornavirus VP7 Ribosomal_L18 PF17135.4 EST49148.1 - 4.7e-43 146.8 1.1 5.4e-43 146.6 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 EST49148.1 - 6.9e-05 23.5 0.4 6.9e-05 23.5 0.4 1.6 2 0 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Raptor_N PF14538.6 EST49150.1 - 5.7e-10 39.3 0.2 5.7e-10 39.3 0.2 4.2 4 0 0 4 4 4 1 Raptor N-terminal CASPase like domain HEAT PF02985.22 EST49150.1 - 0.0009 19.3 0.6 0.92 9.9 0.0 4.2 4 0 0 4 4 4 1 HEAT repeat Rap_GAP PF02145.15 EST49151.1 - 1.5e-32 112.7 0.5 2.4e-32 112.0 0.5 1.3 1 0 0 1 1 1 1 Rap/ran-GAP LRR_9 PF14580.6 EST49152.1 - 3.2e-10 39.8 12.9 2e-07 30.7 4.2 3.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 EST49152.1 - 4.8e-08 33.2 19.8 3.7e-06 27.2 6.2 4.9 1 1 5 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EST49152.1 - 0.00099 18.8 22.4 0.017 14.9 9.4 4.7 2 2 1 3 3 3 1 Leucine rich repeat LRR_1 PF00560.33 EST49152.1 - 0.43 11.3 11.2 14 6.7 0.2 4.9 4 1 0 4 4 4 0 Leucine Rich Repeat DDE_Tnp_ISL3 PF01610.17 EST49152.1 - 0.91 9.2 7.1 0.15 11.8 0.8 2.6 1 1 1 2 2 2 0 Transposase LRR_6 PF13516.6 EST49152.1 - 5.5 7.3 7.3 10 6.4 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich repeat Nsp1_C PF05064.13 EST49153.1 - 0.011 15.6 7.1 0.011 15.6 7.1 1.6 2 0 0 2 2 2 0 Nsp1-like C-terminal region GBP PF02263.19 EST49153.1 - 0.013 14.8 2.9 0.018 14.4 2.9 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain TUG-UBL1 PF11470.8 EST49153.1 - 2.4 8.4 5.3 2.7 8.3 1.8 2.5 2 1 0 2 2 2 0 TUG ubiquitin-like domain Peptidase_M26_C PF07580.14 EST49154.1 - 0.071 11.6 0.2 0.071 11.6 0.2 1.1 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase C-terminal region RVT_1 PF00078.27 EST49155.1 - 0.0011 18.5 0.2 0.0036 16.8 0.1 1.9 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribonuc_L-PSP PF01042.21 EST49156.1 - 6.4e-13 48.8 0.0 7.8e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP HEAT_2 PF13646.6 EST49157.1 - 7.4e-27 93.6 11.7 5.4e-06 26.7 1.1 6.4 4 2 2 6 6 6 6 HEAT repeats HEAT PF02985.22 EST49157.1 - 4e-26 88.8 29.7 0.0065 16.6 0.0 13.4 12 1 2 14 14 14 9 HEAT repeat Vac14_Fab1_bd PF12755.7 EST49157.1 - 4.3e-12 46.5 12.1 0.0029 18.2 0.1 6.7 7 1 1 8 8 8 4 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EST49157.1 - 2.3e-09 37.5 20.0 0.00048 20.2 0.5 5.3 4 1 2 6 6 6 4 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EST49157.1 - 3.4e-07 30.6 14.6 0.0047 17.4 0.3 7.5 8 1 1 9 9 9 2 HEAT-like repeat Adaptin_N PF01602.20 EST49157.1 - 2.7e-06 26.3 21.9 0.0032 16.1 0.2 4.0 1 1 0 2 2 2 2 Adaptin N terminal region Tti2 PF10521.9 EST49157.1 - 0.0032 17.1 1.0 2.5 7.6 0.0 3.9 4 0 0 4 4 4 1 Tti2 family Katanin_con80 PF13925.6 EST49157.1 - 0.049 13.7 4.2 1.1 9.3 0.1 3.3 2 1 1 3 3 3 0 con80 domain of Katanin RIX1 PF08167.12 EST49157.1 - 0.08 12.7 1.4 2.2 8.0 0.1 3.4 3 1 1 4 4 4 0 rRNA processing/ribosome biogenesis Sep15_SelM PF08806.11 EST49157.1 - 0.11 12.7 0.1 30 4.9 0.0 2.7 2 0 0 2 2 2 0 Sep15/SelM redox domain EF-G-binding_N PF07299.11 EST49157.1 - 7.5 7.2 7.5 78 3.9 0.1 4.7 4 1 0 4 4 4 0 Elongation factor G-binding protein, N-terminal PKHD_C PF18331.1 EST49158.1 - 0.019 15.0 0.2 0.096 12.8 0.1 2.2 2 0 0 2 2 2 0 PKHD-type hydroxylase C-terminal domain DUF2603 PF10788.9 EST49159.1 - 0.063 13.3 0.0 0.067 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2603) tRNA_SAD PF07973.14 EST49160.1 - 0.00015 21.8 0.8 0.00015 21.8 0.8 2.1 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain DASH_Dad4 PF08650.10 EST49160.1 - 1.3 9.1 3.5 20 5.2 0.1 2.9 2 1 1 3 3 3 0 DASH complex subunit Dad4 Pkinase PF00069.25 EST49161.1 - 2.2e-68 230.5 0.0 2.7e-68 230.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST49161.1 - 2.5e-34 118.8 0.0 4.6e-34 117.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EST49161.1 - 0.0008 18.8 0.2 0.0015 17.9 0.2 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EST49161.1 - 0.0012 18.8 0.2 0.063 13.2 0.2 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EST49161.1 - 0.0093 15.3 0.2 0.02 14.3 0.2 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.20 EST49161.1 - 0.011 15.1 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase RIO1 PF01163.22 EST49161.1 - 0.02 14.5 0.2 0.039 13.5 0.2 1.5 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 EST49161.1 - 0.035 13.1 0.3 0.052 12.5 0.3 1.3 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 EST49161.1 - 0.12 12.0 0.1 0.38 10.4 0.0 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Chibby PF14645.6 EST49166.1 - 0.0063 16.9 0.2 0.007 16.8 0.2 1.2 1 0 0 1 1 1 1 Chibby family bZIP_2 PF07716.15 EST49166.1 - 0.008 16.2 1.7 0.051 13.7 0.4 2.1 1 1 1 2 2 2 1 Basic region leucine zipper DUF775 PF05603.12 EST49167.1 - 1.1e-13 51.2 1.8 6.7e-09 35.6 0.3 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF775) Exonuc_VII_S PF02609.16 EST49167.1 - 0.079 13.0 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Exonuclease VII small subunit MCM_N PF14551.6 EST49168.1 - 0.0018 18.9 2.3 0.022 15.3 2.1 3.3 1 1 0 1 1 1 1 MCM N-terminal domain Metallophos PF00149.28 EST49169.1 - 4.2e-25 89.4 0.0 8.3e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EST49169.1 - 0.0074 16.5 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain zf_UBZ PF18439.1 EST49171.1 - 0.0037 16.8 1.2 0.39 10.3 0.1 2.7 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger Yippee-Mis18 PF03226.14 EST49171.1 - 0.043 14.0 7.9 0.057 13.6 7.9 1.3 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 EST49171.1 - 0.12 12.6 6.7 0.16 12.2 6.7 1.2 1 0 0 1 1 1 0 C-terminal domain of RIG-I zf-LYAR PF08790.11 EST49171.1 - 0.58 10.1 0.1 0.58 10.1 0.1 3.0 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger TTL PF03133.15 EST49173.1 - 6.6e-68 229.0 4.3 8.9e-68 228.6 4.3 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EST49173.1 - 3.3e-11 42.9 1.0 2.2e-05 23.8 0.0 2.5 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EST49173.1 - 2.6e-05 23.6 0.0 0.17 11.1 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp RimK PF08443.11 EST49173.1 - 0.0011 18.6 0.1 0.57 9.8 0.0 2.2 2 0 0 2 2 2 2 RimK-like ATP-grasp domain LCAT PF02450.15 EST49174.1 - 2.2e-17 63.3 0.0 1.7e-16 60.4 0.0 2.0 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase PGAP1 PF07819.13 EST49174.1 - 3.1e-05 23.8 0.0 0.00051 19.8 0.0 2.3 2 0 0 2 2 2 1 PGAP1-like protein DUF900 PF05990.12 EST49174.1 - 0.00087 18.9 0.0 0.0027 17.3 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) Lipase_2 PF01674.18 EST49174.1 - 0.0023 17.5 0.1 0.0064 16.0 0.1 1.7 1 0 0 1 1 1 1 Lipase (class 2) DUF676 PF05057.14 EST49174.1 - 0.0024 17.4 0.0 0.0056 16.2 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 EST49174.1 - 0.006 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF915 PF06028.11 EST49174.1 - 0.089 12.1 0.0 0.61 9.4 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF3349 PF11829.8 EST49174.1 - 0.15 12.8 0.0 0.49 11.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3349) Pkinase PF00069.25 EST49175.1 - 9.8e-33 113.6 1.7 6.3e-32 111.0 1.7 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST49175.1 - 2.1e-18 66.6 0.3 2.1e-17 63.3 0.3 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase DUF5601 PF18151.1 EST49175.1 - 0.036 14.4 0.4 0.16 12.3 0.4 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF5601) ATP_bind_1 PF03029.17 EST49175.1 - 0.059 13.1 0.1 0.13 12.0 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FTA2 PF13095.6 EST49175.1 - 0.49 10.0 2.6 3.3 7.3 0.0 2.8 3 1 1 4 4 4 0 Kinetochore Sim4 complex subunit FTA2 Rib_recp_KP_reg PF05104.12 EST49176.1 - 6.8 7.7 9.8 12 6.9 9.8 1.3 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region Radical_SAM_C PF16199.5 EST49177.1 - 7.5e-24 83.6 0.1 1.4e-23 82.7 0.1 1.4 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 EST49177.1 - 6.5e-15 55.9 0.0 3e-14 53.7 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_10 PF13673.7 EST49177.1 - 0.0013 18.6 0.1 0.0035 17.3 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EST49177.1 - 0.064 13.5 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family TMF_TATA_bd PF12325.8 EST49178.1 - 1.6 9.0 9.5 1.8 8.8 3.5 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Myotub-related PF06602.14 EST49180.1 - 1e-97 327.3 3.4 1e-97 327.3 3.4 2.6 3 1 0 3 3 3 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 EST49180.1 - 0.0002 21.0 0.0 0.00052 19.7 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Orthopox_A49R PF06489.11 EST49180.1 - 0.0052 17.0 0.4 0.017 15.4 0.4 1.9 1 0 0 1 1 1 1 Orthopoxvirus A49R protein Y_phosphatase3 PF13350.6 EST49180.1 - 0.0069 16.4 0.1 0.049 13.6 0.0 2.2 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.20 EST49180.1 - 0.016 15.0 0.2 0.11 12.3 0.0 2.5 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain STT3 PF02516.14 EST49181.1 - 5.4e-51 174.0 29.4 7.9e-51 173.5 29.4 1.2 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit ETRAMP PF09716.10 EST49181.1 - 2.2 8.4 4.1 18 5.5 0.1 3.0 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) SF-assemblin PF06705.11 EST49182.1 - 9.7e-12 44.7 25.8 1.2e-11 44.4 25.8 1.0 1 0 0 1 1 1 1 SF-assemblin/beta giardin FAM184 PF15665.5 EST49182.1 - 0.0016 18.3 13.9 0.012 15.4 6.5 2.4 1 1 1 2 2 2 2 Family with sequence similarity 184, A and B Vac14_Fab1_bd PF12755.7 EST49182.1 - 0.052 14.2 0.4 0.4 11.3 0.1 2.4 2 1 0 2 2 2 0 Vacuolar 14 Fab1-binding region ApoO PF09769.9 EST49182.1 - 0.12 12.4 4.6 1.6 8.7 0.1 3.1 1 1 2 3 3 3 0 Apolipoprotein O DUF3086 PF11285.8 EST49182.1 - 1 8.4 9.0 6.6 5.7 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3086) Ank_2 PF12796.7 EST49183.1 - 0.25 11.9 3.9 53 4.5 0.0 4.0 4 0 0 4 4 4 0 Ankyrin repeats (3 copies) DUF5320 PF17253.2 EST49184.1 - 0.013 16.5 0.3 0.021 15.9 0.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5320) Elf1 PF05129.13 EST49185.1 - 1.2e-06 28.5 5.8 1.2e-06 28.5 5.8 3.0 3 0 0 3 3 3 2 Transcription elongation factor Elf1 like zf-Di19 PF05605.12 EST49185.1 - 0.003 17.8 1.6 0.0074 16.6 1.6 1.7 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Ank_2 PF12796.7 EST49186.1 - 5e-38 129.6 10.2 7.2e-10 39.3 0.0 4.9 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EST49186.1 - 2.6e-20 72.2 0.1 0.002 18.4 0.0 6.4 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 EST49186.1 - 8.4e-18 64.0 0.1 0.089 13.3 0.0 7.5 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.6 EST49186.1 - 2.2e-17 63.2 4.0 0.00024 21.6 0.0 6.1 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EST49186.1 - 3.7e-15 54.5 0.7 0.29 11.8 0.0 8.3 8 0 0 8 8 8 3 Ankyrin repeat DUF745 PF05335.13 EST49186.1 - 0.0092 15.7 8.9 0.0092 15.7 8.9 5.6 3 2 1 5 5 5 1 Protein of unknown function (DUF745) ANAPC5 PF12862.7 EST49186.1 - 0.039 14.0 1.6 0.23 11.6 1.6 2.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 LptF_LptG PF03739.14 EST49187.1 - 0.93 8.3 5.3 1 8.1 5.3 1.1 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG PAP_assoc PF03828.19 EST49189.1 - 0.0029 17.8 0.2 0.046 13.9 0.0 2.6 3 0 0 3 3 3 1 Cid1 family poly A polymerase Suv3_N PF18114.1 EST49189.1 - 0.038 14.1 0.8 0.16 12.1 0.4 2.2 2 0 0 2 2 2 0 Suv3 helical N-terminal domain DNA_pol3_a_NII PF11490.8 EST49189.1 - 0.14 12.1 5.1 3.4 7.6 0.7 3.1 2 1 0 2 2 2 0 DNA polymerase III polC-type N-terminus II DUF4487 PF14868.6 EST49191.1 - 0.022 13.6 2.4 0.035 12.9 2.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4487) ApbE PF02424.15 EST49192.1 - 0.16 11.5 1.0 0.19 11.2 1.0 1.2 1 0 0 1 1 1 0 ApbE family SecD-TM1 PF13721.6 EST49192.1 - 2.3 8.7 9.0 2.4 8.7 4.1 2.2 1 1 1 2 2 2 0 SecD export protein N-terminal TM region ZapB PF06005.12 EST49192.1 - 4.8 7.7 20.6 42 4.7 18.0 3.2 1 1 1 2 2 2 0 Cell division protein ZapB DUF4407 PF14362.6 EST49192.1 - 6.2 6.1 9.4 7.7 5.8 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tup_N PF08581.10 EST49193.1 - 1.5 9.2 4.9 1.3 9.4 2.5 2.1 2 1 0 2 2 2 0 Tup N-terminal DUF4558 PF15104.6 EST49194.1 - 0.0064 16.5 0.8 0.017 15.2 0.1 1.9 1 1 0 2 2 2 1 Domain of unknown function (DUF4558) RILP PF11461.8 EST49195.1 - 0.17 12.1 2.0 2.5 8.4 0.1 2.2 2 0 0 2 2 2 0 Rab interacting lysosomal protein Fungal_lectin_2 PF18647.1 EST49196.1 - 0.6 10.6 13.6 1.9 9.0 0.6 3.1 2 1 1 3 3 3 0 Alpha-galactosyl-binding fungal lectin DUF739 PF05339.11 EST49197.1 - 2.6 8.3 8.1 0.28 11.3 0.3 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF739) EF-hand_7 PF13499.6 EST49197.1 - 9.3 6.8 8.8 4.3 7.9 0.2 3.9 2 1 0 2 2 2 0 EF-hand domain pair Ribosomal_S14 PF00253.21 EST49199.1 - 5e-11 42.2 1.1 5e-11 42.2 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Helicase_C_2 PF13307.6 EST49200.1 - 3.5e-30 105.4 0.1 7.1e-30 104.4 0.1 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 EST49200.1 - 1.6e-23 83.2 7.4 3.3e-23 82.2 7.4 1.5 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 EST49200.1 - 0.0001 22.4 0.2 0.00035 20.6 0.2 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HBB PF06777.11 EST49200.1 - 0.0014 18.3 0.2 0.018 14.7 0.0 2.7 2 1 1 3 3 3 1 Helical and beta-bridge domain DEAD PF00270.29 EST49200.1 - 0.0055 16.5 0.3 0.28 10.9 0.3 2.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase Tox-PL-2 PF15643.6 EST49200.1 - 0.061 13.5 0.5 1.4 9.0 0.1 2.9 2 0 0 2 2 2 0 Papain fold toxin 2 NAD_Gly3P_dh_C PF07479.14 EST49200.1 - 0.066 13.5 0.6 5.2 7.4 0.1 2.7 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus RP-C PF03428.13 EST49200.1 - 0.18 11.5 0.1 0.36 10.5 0.1 1.5 1 0 0 1 1 1 0 Replication protein C N-terminal domain 7tm_1 PF00001.21 EST49201.1 - 0.06 12.7 0.1 0.073 12.4 0.1 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) O-ag_pol_Wzy PF14296.6 EST49201.1 - 0.068 11.8 0.0 0.088 11.4 0.0 1.1 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy DUF4224 PF13986.6 EST49201.1 - 0.099 12.6 0.0 0.24 11.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) JAB PF01398.21 EST49202.1 - 4.4e-13 49.3 0.0 7.5e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease PP2C PF00481.21 EST49204.1 - 1.9e-42 145.7 0.1 3.2e-42 145.0 0.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EST49204.1 - 0.014 15.4 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) Laminin_II PF06009.12 EST49204.1 - 0.016 15.2 0.8 0.027 14.5 0.8 1.4 1 0 0 1 1 1 0 Laminin Domain II DUF4505 PF14956.6 EST49204.1 - 0.041 13.6 0.4 0.078 12.7 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4505) L1R_F9L PF02442.17 EST49204.1 - 0.044 13.6 2.5 2.9 7.7 0.0 2.3 1 1 1 2 2 2 0 Lipid membrane protein of large eukaryotic DNA viruses YwhD PF08741.10 EST49207.1 - 0.15 11.8 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 YwhD family PP2C PF00481.21 EST49209.1 - 6e-36 124.4 0.0 8.4e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EST49209.1 - 0.003 17.2 0.0 0.0069 16.0 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C DUF4097 PF13349.6 EST49210.1 - 0.0045 16.4 0.1 0.02 14.3 0.1 1.9 2 0 0 2 2 2 1 Putative adhesin Kdo PF06293.14 EST49210.1 - 0.098 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2113 PF09886.9 EST49211.1 - 0.0066 15.8 0.1 0.017 14.5 0.1 1.6 1 1 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2113) Prefoldin_2 PF01920.20 EST49212.1 - 3.2e-11 43.1 0.5 3.8e-11 42.9 0.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit FliD_C PF07195.12 EST49212.1 - 0.0027 17.2 1.2 0.017 14.6 0.1 1.9 2 0 0 2 2 2 1 Flagellar hook-associated protein 2 C-terminus MtrB PF05440.12 EST49212.1 - 0.045 14.2 0.8 11 6.5 0.0 2.2 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B Met_gamma_lyase PF06838.11 EST49212.1 - 0.11 11.0 0.1 0.13 10.7 0.1 1.0 1 0 0 1 1 1 0 Methionine gamma-lyase DUF4988 PF16378.5 EST49212.1 - 0.18 11.5 2.2 1.9 8.1 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function Maf PF02545.14 EST49213.1 - 6.7e-47 159.4 0.0 7.5e-47 159.3 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein SRP68 PF16969.5 EST49214.1 - 1.1e-10 41.2 1.6 1.6e-10 40.6 0.9 1.5 1 1 0 1 1 1 1 RNA-binding signal recognition particle 68 TPR_2 PF07719.17 EST49214.1 - 0.1 12.8 0.0 5.4 7.4 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat AXE1 PF05448.12 EST49215.1 - 0.045 12.4 0.1 0.053 12.2 0.1 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) FUSC-like PF12805.7 EST49215.1 - 0.088 11.9 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS DUF4907 PF16250.5 EST49216.1 - 0.012 15.5 0.7 0.051 13.5 0.7 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4907) MORN PF02493.20 EST49217.1 - 6.3e-82 264.9 80.4 2.8e-07 30.0 0.3 17.5 17 1 0 17 17 17 17 MORN repeat Peptidase_S55 PF05580.12 EST49217.1 - 0.04 13.9 1.2 20 5.0 0.0 4.1 2 1 1 4 4 4 0 SpoIVB peptidase S55 DUF333 PF03891.15 EST49217.1 - 0.12 12.7 1.2 13 6.1 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF333) PhoLip_ATPase_C PF16212.5 EST49218.1 - 1.3e-43 149.6 31.1 1.3e-43 149.6 31.1 3.4 4 0 0 4 4 4 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 EST49218.1 - 5.6e-12 46.4 0.1 2.2e-09 37.9 0.1 2.9 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase PhoLip_ATPase_N PF16209.5 EST49218.1 - 2.4e-11 43.2 4.1 1.2e-10 40.9 4.1 2.3 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 EST49218.1 - 5.5e-10 39.1 2.3 1.4e-09 37.7 0.0 2.8 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EST49218.1 - 1.3e-06 28.4 1.7 4e-06 26.8 1.7 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EST49218.1 - 0.00044 20.3 0.0 0.0016 18.5 0.0 2.0 1 0 0 1 1 1 1 Cation transport ATPase (P-type) E2_bind PF08825.10 EST49218.1 - 0.022 14.9 1.8 7.9 6.7 0.9 2.7 2 0 0 2 2 2 0 E2 binding domain MFS_1 PF07690.16 EST49219.1 - 6.7e-17 61.4 54.8 1.3e-16 60.5 51.1 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FGF PF00167.18 EST49220.1 - 0.0015 18.7 0.0 0.008 16.3 0.0 2.5 1 1 0 1 1 1 1 Fibroblast growth factor MCM6_C PF18263.1 EST49221.1 - 0.22 11.7 5.8 7.7 6.8 5.8 2.3 1 1 0 1 1 1 0 MCM6 C-terminal winged-helix domain Cgr1 PF03879.14 EST49222.1 - 0.0029 18.0 14.3 0.0042 17.5 14.3 1.2 1 0 0 1 1 1 1 Cgr1 family Com_YlbF PF06133.11 EST49222.1 - 0.011 16.3 8.0 0.014 16.0 8.0 1.1 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA BRE1 PF08647.11 EST49222.1 - 0.21 11.6 13.7 0.61 10.2 8.1 2.0 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Acyltransferase PF01553.21 EST49223.1 - 1.5e-08 34.3 0.1 4.9e-08 32.7 0.1 1.8 1 1 0 1 1 1 1 Acyltransferase PHO4 PF01384.20 EST49223.1 - 0.14 11.2 0.1 0.13 11.2 0.1 1.1 1 0 0 1 1 1 0 Phosphate transporter family SNF2_N PF00176.23 EST49225.1 - 7.8e-39 133.4 5.0 7.8e-39 133.4 5.0 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EST49225.1 - 1.4e-15 57.5 3.8 4e-15 56.1 0.9 3.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EST49225.1 - 0.00011 22.3 0.5 0.00011 22.3 0.5 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit p25-alpha PF05517.12 EST49226.1 - 0.00053 20.2 1.4 0.0021 18.3 1.5 2.1 1 1 0 1 1 1 1 p25-alpha Sec23_helical PF04815.15 EST49226.1 - 3.7 7.4 6.2 3.5 7.5 0.3 3.1 3 1 0 3 3 3 0 Sec23/Sec24 helical domain DUF3120 PF11318.8 EST49227.1 - 0.074 13.4 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) S1 PF00575.23 EST49228.1 - 2.6e-09 37.3 0.2 6.6e-07 29.6 0.2 2.8 2 0 0 2 2 2 1 S1 RNA binding domain TPR_14 PF13428.6 EST49228.1 - 4.5e-05 23.9 6.2 0.062 14.1 0.2 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat SH3_13 PF18335.1 EST49228.1 - 0.061 13.2 0.0 0.32 10.9 0.0 2.2 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain TPR_19 PF14559.6 EST49228.1 - 0.11 13.0 4.9 0.86 10.2 0.5 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EST49228.1 - 0.43 10.9 2.9 2.4 8.5 0.1 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat S1 PF00575.23 EST49230.1 - 7.6e-05 23.0 0.5 0.011 16.1 0.0 4.0 3 0 0 3 3 3 1 S1 RNA binding domain TPR_8 PF13181.6 EST49230.1 - 0.0025 17.9 2.2 0.027 14.7 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EST49230.1 - 0.95 9.7 4.3 1.6 9.1 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat T4_Gp59_C PF08994.10 EST49231.1 - 0.21 12.2 6.5 0.11 13.1 3.5 2.1 2 0 0 2 2 2 0 T4 gene Gp59 loader of gp41 DNA helicase C-term DUF4384 PF14326.6 EST49232.1 - 0.033 14.3 0.1 0.066 13.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4384) SLAM PF06214.11 EST49232.1 - 0.1 12.6 1.5 0.25 11.3 1.4 1.7 1 1 1 2 2 2 0 Signaling lymphocytic activation molecule (SLAM) protein Trans_reg_C PF00486.28 EST49232.1 - 0.2 11.8 1.9 5.2 7.2 0.0 2.7 2 1 1 3 3 3 0 Transcriptional regulatory protein, C terminal APG6_N PF17675.1 EST49232.1 - 0.32 11.5 11.3 0.18 12.3 5.3 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region NleF_casp_inhib PF16809.5 EST49232.1 - 0.43 10.5 16.2 0.43 10.5 3.2 2.9 2 1 0 2 2 2 0 NleF caspase inhibitor DUF3130 PF11328.8 EST49232.1 - 0.63 10.3 6.2 0.42 10.9 2.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3130 DUF1664 PF07889.12 EST49232.1 - 0.98 9.5 12.1 3.3 7.8 0.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 EST49232.1 - 3.7 7.9 8.8 0.63 10.3 0.1 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4446 PF14584.6 EST49232.1 - 4.5 7.2 13.9 5.9 6.9 2.9 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF4446) DUF16 PF01519.16 EST49232.1 - 4.8 7.7 18.5 12 6.4 9.9 2.6 2 1 0 2 2 2 0 Protein of unknown function DUF16 TMF_TATA_bd PF12325.8 EST49232.1 - 5 7.4 10.5 5.8 7.2 3.2 3.1 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding KxDL PF10241.9 EST49232.1 - 5.3 7.4 22.9 2.4 8.5 0.3 3.9 3 2 0 3 3 3 0 Uncharacterized conserved protein IFT20 PF14931.6 EST49232.1 - 5.5 7.2 13.3 1.1 9.4 8.2 2.5 2 1 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 LRR_4 PF12799.7 EST49233.1 - 0.00036 20.9 4.5 0.36 11.3 0.8 3.0 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) TT1725 PF18324.1 EST49233.1 - 0.013 15.6 0.7 0.025 14.7 0.5 1.6 2 0 0 2 2 2 0 Hypothetical protein TT1725 LRR_8 PF13855.6 EST49233.1 - 0.085 12.6 2.5 1.7 8.4 1.8 2.7 1 1 2 3 3 3 0 Leucine rich repeat AAA_assoc PF14363.6 EST49234.1 - 0.0023 18.2 2.1 0.0024 18.2 0.8 1.7 2 0 0 2 2 2 1 Domain associated at C-terminal with AAA MIT_C PF16565.5 EST49234.1 - 0.0073 16.3 3.9 0.0073 16.3 3.9 1.9 1 1 1 2 2 2 1 Phospholipase D-like domain at C-terminus of MIT Med9 PF07544.13 EST49234.1 - 0.0088 16.1 4.3 0.0088 16.1 4.3 3.0 2 1 1 3 3 3 1 RNA polymerase II transcription mediator complex subunit 9 Erf4 PF10256.9 EST49234.1 - 0.19 11.9 3.9 0.25 11.5 1.1 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family Rx_N PF18052.1 EST49234.1 - 0.25 11.7 3.9 3.2 8.1 0.8 2.4 1 1 0 2 2 2 0 Rx N-terminal domain Phage_lysozyme PF00959.19 EST49234.1 - 0.3 11.6 2.5 0.52 10.8 2.4 1.7 1 1 0 1 1 1 0 Phage lysozyme TCTP PF00838.17 EST49234.1 - 0.74 10.1 9.5 0.25 11.7 2.3 2.3 1 1 2 3 3 3 0 Translationally controlled tumour protein BST2 PF16716.5 EST49234.1 - 1.4 9.5 12.2 0.068 13.8 3.9 2.7 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 Prefoldin_2 PF01920.20 EST49234.1 - 1.6 8.7 16.9 0.064 13.2 4.4 3.3 2 1 2 4 4 4 0 Prefoldin subunit Peptidase_C1 PF00112.23 EST49235.1 - 2.3e-58 197.8 7.9 2.7e-58 197.6 7.9 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EST49235.1 - 1.8e-08 33.6 3.0 0.0013 17.6 0.3 2.2 2 0 0 2 2 2 2 Peptidase C1-like family DUF1746 PF08508.10 EST49235.1 - 0.2 12.0 0.0 0.33 11.3 0.0 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1746) DNA_binding_1 PF01035.20 EST49237.1 - 0.052 13.7 0.0 0.16 12.1 0.0 1.8 2 0 0 2 2 2 0 6-O-methylguanine DNA methyltransferase, DNA binding domain CBM-like PF14683.6 EST49237.1 - 0.06 13.2 0.0 0.41 10.5 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide lyase family 4, domain III DUF4164 PF13747.6 EST49238.1 - 0.00083 19.6 7.4 0.00083 19.6 7.4 4.0 3 1 1 4 4 4 2 Domain of unknown function (DUF4164) End3 PF12761.7 EST49238.1 - 0.0068 16.6 25.2 0.045 13.9 7.9 2.8 2 1 0 3 3 3 2 Actin cytoskeleton-regulatory complex protein END3 UPF0242 PF06785.11 EST49238.1 - 0.0095 16.1 33.9 0.12 12.5 7.9 3.1 2 1 1 3 3 3 3 Uncharacterised protein family (UPF0242) N-terminus MH1 PF03165.16 EST49238.1 - 0.077 13.2 4.4 0.085 13.1 0.5 2.7 2 1 0 2 2 2 0 MH1 domain Ank_2 PF12796.7 EST49239.1 - 8.9e-18 64.7 9.5 5.5e-15 55.7 0.3 3.9 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 EST49239.1 - 3.9e-11 42.9 2.5 0.011 16.2 0.0 4.6 4 1 1 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 EST49239.1 - 1.5e-10 41.4 3.2 2.2e-08 34.5 0.1 3.4 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EST49239.1 - 2.2e-10 39.8 3.0 0.056 14.0 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EST49239.1 - 1.8e-08 34.5 6.6 8.7e-05 22.7 0.0 5.5 5 1 2 7 7 7 2 Ankyrin repeats (many copies) DUF3267 PF11667.8 EST49242.1 - 0.12 12.6 0.3 0.12 12.6 0.3 4.3 4 1 0 4 4 4 0 Putative zincin peptidase DUF5383 PF17355.2 EST49242.1 - 7.1 7.0 7.4 0.53 10.7 0.2 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5383) DUF4065 PF13274.6 EST49243.1 - 0.03 15.2 8.2 0.075 13.9 4.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4065) Aida_N PF08910.10 EST49243.1 - 0.039 14.4 0.6 0.61 10.5 0.0 2.3 2 0 0 2 2 2 0 Aida N-terminus WD40_like PF17005.5 EST49244.1 - 5.3e-05 22.7 0.1 0.00047 19.6 0.1 1.8 1 1 0 1 1 1 1 WD40-like domain WD40 PF00400.32 EST49244.1 - 0.00047 20.9 0.1 11 7.1 0.0 4.9 5 1 1 6 6 6 2 WD domain, G-beta repeat Herpes_PAP PF03325.13 EST49244.1 - 0.039 13.5 0.1 0.25 10.9 0.1 1.9 2 0 0 2 2 2 0 Herpesvirus polymerase accessory protein PRP9_N PF16958.5 EST49246.1 - 0.028 14.4 7.3 0.89 9.6 2.3 2.3 1 1 1 2 2 2 0 Pre-mRNA-splicing factor PRP9 N-terminus Fur_reg_FbpB PF13040.6 EST49246.1 - 0.037 13.6 0.4 0.12 11.9 0.4 1.9 1 0 0 1 1 1 0 Fur-regulated basic protein B Sod_Ni PF09055.11 EST49246.1 - 0.17 12.4 1.0 0.35 11.4 1.0 1.5 1 1 0 1 1 1 0 Nickel-containing superoxide dismutase DLEU7 PF15760.5 EST49246.1 - 0.22 11.0 0.5 0.31 10.5 0.5 1.2 1 0 0 1 1 1 0 Leukemia-associated protein 7 CUE PF02845.16 EST49246.1 - 0.34 10.7 0.0 0.34 10.7 0.0 2.3 3 0 0 3 3 3 0 CUE domain AAA_31 PF13614.6 EST49246.1 - 1.6 8.6 7.9 0.36 10.7 0.6 2.2 1 1 1 2 2 2 0 AAA domain DUF1397 PF07165.11 EST49248.1 - 0.047 13.1 0.2 0.086 12.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1397) CBM-like PF14683.6 EST49250.1 - 0.062 13.2 0.0 0.41 10.5 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide lyase family 4, domain III DNA_binding_1 PF01035.20 EST49250.1 - 0.075 13.2 0.0 0.23 11.6 0.0 1.8 2 0 0 2 2 2 0 6-O-methylguanine DNA methyltransferase, DNA binding domain Sec5 PF15469.6 EST49251.1 - 0.0048 16.7 0.4 0.0053 16.6 0.4 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec5 G2F PF07474.12 EST49251.1 - 0.07 12.9 0.0 0.075 12.8 0.0 1.0 1 0 0 1 1 1 0 G2F domain Jnk-SapK_ap_N PF09744.9 EST49253.1 - 0.0031 17.8 15.5 0.0031 17.8 15.5 3.4 2 1 1 3 3 3 1 JNK_SAPK-associated protein-1 DUF5371 PF17341.2 EST49253.1 - 0.44 10.8 4.7 12 6.2 0.3 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5371) FlaC_arch PF05377.11 EST49253.1 - 1.2 9.6 24.6 0.86 10.0 2.2 5.3 3 1 2 5 5 5 0 Flagella accessory protein C (FlaC) Snapin_Pallidin PF14712.6 EST49253.1 - 2.1 8.8 33.0 1.5 9.3 1.8 4.7 3 1 1 4 4 4 0 Snapin/Pallidin Lebercilin PF15619.6 EST49253.1 - 5.2 6.7 38.6 0.057 13.1 24.2 3.6 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease CENP-F_leu_zip PF10473.9 EST49253.1 - 6.2 6.8 39.7 0.87 9.6 21.7 3.7 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KASH_CCD PF14662.6 EST49253.1 - 8.6 6.1 42.0 0.029 14.2 25.8 3.8 2 2 2 4 4 4 0 Coiled-coil region of CCDC155 or KASH WXG100 PF06013.12 EST49253.1 - 9.5 6.5 14.5 6.3 7.1 1.9 3.7 3 1 0 3 3 3 0 Proteins of 100 residues with WXG DUF1664 PF07889.12 EST49253.1 - 9.6 6.3 24.6 9.4 6.3 0.3 3.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) F_bP_aldolase PF01116.20 EST49254.1 - 2.7e-101 338.8 0.8 3.5e-101 338.4 0.8 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II CutC PF03932.14 EST49254.1 - 0.012 15.1 0.1 0.031 13.7 0.1 1.6 1 0 0 1 1 1 0 CutC family DUF4773 PF15998.5 EST49255.1 - 2.9 8.5 6.0 1.4 9.5 0.4 3.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4773) Annexin PF00191.20 EST49256.1 - 3.5e-26 91.0 7.0 2.3e-10 40.4 0.1 4.8 4 1 0 4 4 4 4 Annexin TarS_C1 PF18674.1 EST49256.1 - 0.069 13.1 0.2 0.24 11.3 0.0 1.9 2 0 0 2 2 2 0 TarS beta-glycosyltransferase C-terminal domain 1 ThiF PF00899.21 EST49257.1 - 0.017 14.5 0.6 2.9 7.2 0.0 2.0 1 1 1 2 2 2 0 ThiF family SMC_N PF02463.19 EST49258.1 - 2e-24 86.3 23.0 3.7e-15 56.0 6.3 3.8 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EST49258.1 - 7.5e-10 39.1 31.1 7.5e-10 39.1 31.1 4.5 2 2 1 3 3 3 1 AAA ATPase domain SMC_hinge PF06470.13 EST49258.1 - 2e-09 37.8 0.0 8.4e-09 35.8 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EST49258.1 - 2.8e-09 37.2 0.6 1.9e-05 24.7 0.1 3.9 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EST49258.1 - 1.2e-05 24.9 0.1 5.1e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain Sec16 PF12932.7 EST49258.1 - 3.1 8.4 5.4 1.6 9.3 1.4 2.7 2 0 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region GCN5L1 PF06320.13 EST49259.1 - 2.7e-10 40.4 3.4 3.1e-10 40.2 3.4 1.1 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) Aha1_N PF09229.11 EST49262.1 - 1.4e-17 64.1 6.8 1.7e-17 63.9 6.8 1.0 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal HAP1_N PF04849.13 EST49263.1 - 0.0032 16.7 36.5 0.14 11.3 36.5 2.3 1 1 0 1 1 1 1 HAP1 N-terminal conserved region PRKG1_interact PF15898.5 EST49263.1 - 0.017 16.0 8.4 0.017 16.0 8.4 3.5 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain Spc7 PF08317.11 EST49263.1 - 0.17 10.8 36.8 0.46 9.3 8.9 2.2 1 1 0 2 2 2 0 Spc7 kinetochore protein DUF932 PF06067.11 EST49263.1 - 4 7.1 7.3 11 5.7 0.0 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF932) DUF1931 PF09123.11 EST49266.1 - 0.033 14.3 0.1 0.069 13.3 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1931) Actin PF00022.19 EST49267.1 - 2e-35 122.2 0.0 6.9e-19 67.7 0.3 2.2 1 1 1 2 2 2 2 Actin Toprim_3 PF13362.6 EST49267.1 - 0.023 15.1 0.0 0.047 14.0 0.0 1.5 1 0 0 1 1 1 0 Toprim domain PseudoU_synth_1 PF01416.20 EST49268.1 - 3.7e-11 43.4 0.0 1.9e-07 31.5 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase CRISPR_Cas2 PF09827.9 EST49270.1 - 0.11 12.7 0.2 0.29 11.4 0.1 1.7 1 1 0 1 1 1 0 CRISPR associated protein Cas2 Aa_trans PF01490.18 EST49271.1 - 1.9e-22 79.6 33.1 2.4e-22 79.2 33.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein bZIP_1 PF00170.21 EST49275.1 - 2.8 8.1 21.7 0.93 9.6 0.3 5.4 3 1 2 5 5 5 0 bZIP transcription factor DUF5001 PF16392.5 EST49276.1 - 0.014 15.2 0.7 0.095 12.6 0.1 2.2 2 0 0 2 2 2 0 Ig-like domain Mob1_phocein PF03637.17 EST49277.1 - 5.5e-38 130.6 1.0 6.2e-38 130.5 1.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family RNA_pol_Rpc4 PF05132.14 EST49278.1 - 1.6e-06 28.6 12.4 2.7e-05 24.7 12.4 2.7 1 1 0 1 1 1 1 RNA polymerase III RPC4 DUF3338 PF11819.8 EST49278.1 - 0.0044 17.0 0.2 0.0078 16.2 0.2 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3338) CopK PF11525.8 EST49278.1 - 0.043 13.4 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 Copper resistance protein K Acyltransferase PF01553.21 EST49279.1 - 0.00042 19.9 0.0 0.0014 18.2 0.0 1.8 1 1 0 1 1 1 1 Acyltransferase UBA_4 PF14555.6 EST49280.1 - 2.8e-05 23.8 0.1 7.5e-05 22.5 0.1 1.7 1 0 0 1 1 1 1 UBA-like domain GAGBD PF16828.5 EST49280.1 - 0.0074 16.4 0.6 0.015 15.4 0.6 1.5 1 0 0 1 1 1 1 GAG-binding domain on surface antigen Smr PF01713.21 EST49280.1 - 0.0075 16.6 0.1 0.02 15.2 0.1 1.8 1 1 0 1 1 1 1 Smr domain Helicase_PWI PF18149.1 EST49280.1 - 0.0084 16.3 1.0 0.019 15.2 1.0 1.7 1 0 0 1 1 1 1 N-terminal helicase PWI domain TBCC PF07986.12 EST49281.1 - 3.5e-18 65.5 1.0 7.6e-18 64.4 1.0 1.6 1 0 0 1 1 1 1 Tubulin binding cofactor C Cyclin_C PF02984.19 EST49282.1 - 8e-15 55.0 1.1 2.1e-14 53.6 0.2 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain DUF3385 PF11865.8 EST49282.1 - 6.4e-05 22.9 0.7 0.28 11.1 0.5 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3385) Cyclin_N PF00134.23 EST49282.1 - 0.11 12.3 3.9 0.12 12.1 1.3 2.0 2 0 0 2 2 2 0 Cyclin, N-terminal domain 5_3_exonuc_N PF02739.16 EST49283.1 - 0.022 14.6 0.5 0.022 14.6 0.5 2.0 2 1 1 3 3 3 0 5'-3' exonuclease, N-terminal resolvase-like domain DUF2228 PF10228.9 EST49284.1 - 0.0038 17.0 2.2 0.0044 16.8 2.2 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2228) Sipho_Gp157 PF05565.11 EST49284.1 - 0.0073 16.3 2.3 0.0078 16.2 2.3 1.1 1 0 0 1 1 1 1 Siphovirus Gp157 ZapB PF06005.12 EST49284.1 - 0.0074 16.7 7.2 0.032 14.7 2.8 2.1 1 1 1 2 2 2 1 Cell division protein ZapB DUF4337 PF14235.6 EST49284.1 - 0.012 15.8 0.6 0.013 15.6 0.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) BORCS7 PF16088.5 EST49284.1 - 0.013 15.7 5.8 0.017 15.4 5.8 1.1 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 7 Spectrin PF00435.21 EST49284.1 - 0.016 15.7 7.1 0.032 14.7 7.1 1.5 1 1 0 1 1 1 0 Spectrin repeat BLOC1_2 PF10046.9 EST49284.1 - 0.021 15.1 7.8 0.036 14.4 7.8 1.4 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3958 PF13125.6 EST49284.1 - 0.024 14.8 4.3 0.024 14.8 4.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3958) ADIP PF11559.8 EST49284.1 - 0.056 13.5 10.2 0.065 13.3 10.2 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF848 PF05852.11 EST49284.1 - 0.085 13.0 4.6 0.1 12.7 4.6 1.1 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) KLRAQ PF10205.9 EST49284.1 - 0.093 13.0 7.9 0.088 13.1 6.4 1.6 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Nup54 PF13874.6 EST49284.1 - 0.096 12.8 5.6 0.092 12.9 4.5 1.5 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF2247 PF10004.9 EST49284.1 - 0.099 12.4 2.8 0.15 11.8 2.8 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) FliJ PF02050.16 EST49284.1 - 0.12 12.6 8.6 0.14 12.4 8.6 1.2 1 0 0 1 1 1 0 Flagellar FliJ protein MtrB PF05440.12 EST49284.1 - 0.15 12.5 0.7 0.24 11.8 0.7 1.4 1 1 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B DUF1664 PF07889.12 EST49284.1 - 0.18 11.8 8.0 0.7 9.9 8.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) UPF0449 PF15136.6 EST49284.1 - 0.21 12.1 4.5 0.28 11.7 4.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Phage_GPO PF05929.11 EST49284.1 - 0.28 10.8 4.6 0.27 10.8 4.6 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase YabA PF06156.13 EST49284.1 - 0.28 11.8 8.1 0.27 11.9 2.4 2.1 1 1 1 2 2 2 0 Initiation control protein YabA Fzo_mitofusin PF04799.13 EST49284.1 - 0.37 10.3 5.7 0.44 10.1 5.7 1.1 1 0 0 1 1 1 0 fzo-like conserved region DUF948 PF06103.11 EST49284.1 - 0.77 10.1 6.5 1.1 9.6 4.2 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4175 PF13779.6 EST49284.1 - 1.4 6.7 8.5 1.6 6.5 8.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DASH_Dam1 PF08653.10 EST49284.1 - 2.4 8.0 9.8 1.1 9.2 1.0 2.9 1 1 2 3 3 3 0 DASH complex subunit Dam1 DivIC PF04977.15 EST49284.1 - 2.5 7.9 9.5 0.38 10.6 4.4 1.9 1 1 1 2 2 2 0 Septum formation initiator bZIP_2 PF07716.15 EST49284.1 - 3.1 8.0 10.8 0.83 9.8 0.5 2.9 2 1 1 3 3 3 0 Basic region leucine zipper AI-2E_transport PF01594.16 EST49284.1 - 6.4 5.8 6.6 14 4.8 6.6 1.6 1 1 0 1 1 1 0 AI-2E family transporter RuvB_N PF05496.12 EST49285.1 - 0.073 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DUF29 PF01724.16 EST49286.1 - 2.7 8.2 14.0 5.1 7.3 1.4 2.5 1 1 1 2 2 2 0 Domain of unknown function DUF29 MMR_HSR1 PF01926.23 EST49287.1 - 0.00069 19.7 0.0 0.0016 18.5 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 EST49287.1 - 0.0034 17.0 0.0 0.19 11.3 0.0 2.7 2 1 0 2 2 2 1 Ras family RIIa PF02197.17 EST49287.1 - 0.0037 16.9 0.5 0.0078 15.9 0.2 1.7 2 0 0 2 2 2 1 Regulatory subunit of type II PKA R-subunit Roc PF08477.13 EST49287.1 - 0.032 14.5 0.0 0.076 13.2 0.0 1.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Cyc-maltodext_C PF10438.9 EST49287.1 - 0.034 14.2 0.9 0.15 12.1 0.9 2.0 1 1 0 1 1 1 0 Cyclo-malto-dextrinase C-terminal domain TniB PF05621.11 EST49287.1 - 0.098 12.1 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Abhydrolase_1 PF00561.20 EST49288.1 - 2.6e-08 33.8 0.1 6.7e-08 32.5 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EST49288.1 - 8.3e-07 29.8 0.0 8.4e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EST49288.1 - 3.4e-06 26.5 0.1 3.1e-05 23.4 0.0 2.0 1 1 0 2 2 2 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 EST49288.1 - 0.0004 20.3 0.8 0.019 14.9 0.0 2.8 2 1 1 3 3 3 1 Lipase (class 3) FSH1 PF03959.13 EST49288.1 - 0.0041 16.8 0.3 0.024 14.3 0.1 2.2 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Thioesterase PF00975.20 EST49288.1 - 0.0097 16.0 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain BAAT_C PF08840.11 EST49288.1 - 0.016 15.1 0.2 0.029 14.3 0.2 1.6 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal CoA_binding_2 PF13380.6 EST49290.1 - 9.9e-08 32.5 0.0 2.2e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 CoA binding domain AAA_18 PF13238.6 EST49292.1 - 0.71 10.4 3.0 0.52 10.9 0.3 2.3 2 1 0 2 2 2 0 AAA domain PAH PF02671.21 EST49292.1 - 0.74 10.0 3.9 1 9.6 0.2 3.4 3 0 0 3 3 3 0 Paired amphipathic helix repeat Vps35 PF03635.17 EST49293.1 - 3.2e-20 72.2 24.2 5e-09 35.3 20.0 4.0 2 1 0 2 2 2 2 Vacuolar protein sorting-associated protein 35 F-112 PF09645.10 EST49293.1 - 0.018 15.1 1.1 0.1 12.7 0.2 2.6 2 0 0 2 2 2 0 F-112 protein Tubulin PF00091.25 EST49294.1 - 5.7e-66 222.5 0.0 9.2e-66 221.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EST49294.1 - 1.3e-50 170.7 0.1 2.6e-50 169.8 0.1 1.5 2 0 0 2 2 2 1 Tubulin C-terminal domain CAP_N PF01213.19 EST49296.1 - 0.18 11.3 4.1 0.19 11.1 4.1 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF2937 PF11157.8 EST49296.1 - 0.32 10.7 2.0 0.39 10.4 1.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2937) YtxH PF12732.7 EST49296.1 - 0.44 11.1 3.7 13 6.4 3.7 2.4 1 1 0 1 1 1 0 YtxH-like protein DUF1974 PF09317.11 EST49296.1 - 1 8.9 5.1 1.3 8.6 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) DUF3713 PF12506.8 EST49296.1 - 1.6 9.0 8.0 0.64 10.3 0.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3713) DUF2433 PF10360.9 EST49296.1 - 4 7.6 7.1 21 5.2 7.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2433) LMBR1 PF04791.16 EST49296.1 - 4.4 6.1 7.8 5.1 5.9 7.8 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2018 PF09442.10 EST49296.1 - 9.6 7.3 13.4 5.5 8.0 5.2 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF2018) Tcp10_C PF07202.13 EST49297.1 - 1.7e-21 76.9 1.2 1.7e-21 76.9 1.2 2.5 4 0 0 4 4 4 1 T-complex protein 10 C-terminus zf-CCCH_7 PF18586.1 EST49297.1 - 0.94 9.9 4.5 0.5 10.7 1.0 2.4 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 DUF494 PF04361.13 EST49298.1 - 0.015 15.2 0.0 0.018 15.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF494) Ribosomal_S8e PF01201.22 EST49299.1 - 0.01 16.0 0.4 0.013 15.7 0.4 1.2 1 0 0 1 1 1 0 Ribosomal protein S8e CtsR PF05848.11 EST49299.1 - 0.026 14.4 0.1 0.044 13.7 0.1 1.4 1 0 0 1 1 1 0 CtsR N-terminal HTH domain CHDCT2 PF08074.11 EST49299.1 - 0.028 14.6 1.8 0.031 14.5 1.8 1.2 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain TRADD_N PF09034.10 EST49299.1 - 0.032 14.3 0.9 0.053 13.6 0.9 1.3 1 0 0 1 1 1 0 TRADD, N-terminal domain DUF4366 PF14283.6 EST49299.1 - 0.046 13.8 0.7 0.057 13.5 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) TruD PF01142.18 EST49300.1 - 1.2e-34 119.9 0.2 1.1e-33 116.7 0.1 2.5 2 1 0 2 2 2 1 tRNA pseudouridine synthase D (TruD) PhetRS_B1 PF18262.1 EST49300.1 - 0.1 12.8 0.0 4.7 7.5 0.0 2.8 2 0 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain DUF775 PF05603.12 EST49301.1 - 0.00012 21.7 2.3 0.13 11.8 0.0 2.1 1 1 0 2 2 2 2 Protein of unknown function (DUF775) Helicase_IV_N PF12462.8 EST49303.1 - 1.6 8.7 9.7 4.6 7.2 2.9 2.2 2 0 0 2 2 2 0 DNA helicase IV / RNA helicase N terminal ADP_ribosyl_GH PF03747.14 EST49306.1 - 3.7e-42 145.0 0.0 4.6e-42 144.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase FERM_M PF00373.18 EST49306.1 - 0.068 13.6 0.6 0.13 12.6 0.3 1.4 1 1 0 1 1 1 0 FERM central domain NIF PF03031.18 EST49307.1 - 2e-36 125.1 1.4 2.8e-36 124.6 1.4 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase MHC_II_alpha PF00993.20 EST49307.1 - 0.12 12.1 0.0 9.2 6.0 0.0 2.6 2 0 0 2 2 2 0 Class II histocompatibility antigen, alpha domain Cyclin PF08613.11 EST49308.1 - 4e-11 43.6 1.5 1e-10 42.2 1.5 1.8 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EST49308.1 - 1.2e-05 25.1 0.2 1.9e-05 24.4 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain SWIRM PF04433.17 EST49308.1 - 0.00042 20.6 0.0 0.00099 19.4 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain Pkinase PF00069.25 EST49309.1 - 2.5e-50 171.3 0.0 2.9e-50 171.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST49309.1 - 1.3e-23 83.6 0.0 2e-23 83.0 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 EST49309.1 - 0.007 15.4 0.4 0.086 11.8 0.4 2.1 1 1 1 2 2 2 1 Poxvirus serine/threonine protein kinase APH PF01636.23 EST49309.1 - 0.03 14.3 0.1 0.048 13.6 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family DNApol3-delta_C PF09115.10 EST49309.1 - 0.042 14.3 0.4 0.1 13.1 0.4 1.6 1 0 0 1 1 1 0 DNA polymerase III, delta subunit, C terminal RIO1 PF01163.22 EST49309.1 - 0.073 12.7 0.1 0.68 9.5 0.1 2.0 1 1 1 2 2 2 0 RIO1 family PH_2 PF08458.10 EST49309.1 - 0.11 12.8 0.1 1.2 9.5 0.0 2.5 3 0 0 3 3 3 0 Plant pleckstrin homology-like region DMA PF03474.14 EST49309.1 - 0.15 11.7 0.0 0.55 9.9 0.0 2.0 1 0 0 1 1 1 0 DMRTA motif Nuf2 PF03800.14 EST49312.1 - 5.5e-12 46.0 4.5 3.5e-11 43.4 4.5 2.4 1 1 0 1 1 1 1 Nuf2 family ZapB PF06005.12 EST49312.1 - 6.2e-05 23.4 1.7 6.2e-05 23.4 1.7 3.0 2 1 0 2 2 2 1 Cell division protein ZapB bZIP_1 PF00170.21 EST49312.1 - 0.014 15.4 1.1 0.052 13.7 0.0 2.7 2 1 0 2 2 2 0 bZIP transcription factor Mga PF05043.13 EST49312.1 - 0.085 13.4 3.6 0.49 11.0 3.6 2.4 1 0 0 1 1 1 0 Mga helix-turn-helix domain DUF948 PF06103.11 EST49312.1 - 0.1 12.9 8.2 2 8.8 0.2 4.1 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF573 PF04504.14 EST49312.1 - 0.11 13.1 2.3 10 6.9 0.0 3.2 3 1 1 4 4 4 0 Protein of unknown function, DUF573 LPP PF04728.13 EST49312.1 - 2.4 8.6 8.9 1.7 9.1 1.7 3.9 3 1 0 3 3 3 0 Lipoprotein leucine-zipper Fez1 PF06818.15 EST49312.1 - 5 7.5 14.6 1.4e+03 -0.4 14.2 2.2 1 1 0 1 1 1 0 Fez1 TPR_MLP1_2 PF07926.12 EST49312.1 - 5.1 7.2 10.7 5.4 7.1 0.1 3.6 1 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein CENP-H PF05837.12 EST49312.1 - 5.2 7.5 14.9 0.59 10.6 3.6 3.2 1 1 2 3 3 3 0 Centromere protein H (CENP-H) Laminin_II PF06009.12 EST49312.1 - 7.1 6.6 12.4 3.6 7.6 0.5 3.4 3 1 1 4 4 4 0 Laminin Domain II MFS_1 PF07690.16 EST49313.1 - 6.4e-10 38.5 32.6 6.4e-10 38.5 32.6 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF2633 PF11119.8 EST49313.1 - 0.52 10.3 0.0 0.52 10.3 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2633) DUF4231 PF14015.6 EST49313.1 - 7.5 7.1 8.2 1.1 9.7 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Transposase_1 PF01359.18 EST49315.1 - 0.13 12.1 3.0 0.46 10.3 0.0 3.4 3 0 0 3 3 3 0 Transposase (partial DDE domain) SET PF00856.28 EST49316.1 - 1.8e-11 44.8 0.1 2e-11 44.6 0.1 1.4 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 EST49316.1 - 2.2e-05 24.4 11.8 2.2e-05 24.4 11.8 2.1 2 1 0 2 2 2 1 MYND finger Acyltransferase PF01553.21 EST49318.1 - 1.4e-11 44.2 0.0 7.2e-11 41.8 0.0 2.0 1 1 1 2 2 2 1 Acyltransferase Histone PF00125.24 EST49319.1 - 1.6e-21 77.0 3.8 1.8e-21 76.8 3.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EST49319.1 - 1.2e-05 25.4 0.4 1.7e-05 24.9 0.4 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 EST49319.1 - 0.0023 18.2 0.4 0.0045 17.3 0.4 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 EST49319.1 - 0.0049 17.2 0.7 0.009 16.4 0.7 1.6 1 1 0 1 1 1 1 CENP-S protein Aa_trans PF01490.18 EST49320.1 - 1.7e-28 99.5 41.5 3e-28 98.7 41.5 1.4 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EST49320.1 - 1.5e-05 24.2 27.9 1.5e-05 24.2 27.9 3.5 2 1 2 4 4 4 1 Tryptophan/tyrosine permease family Phosphorylase PF00343.20 EST49321.1 - 6.4e-278 923.9 1.1 8.5e-278 923.4 0.1 1.6 2 0 0 2 2 2 1 Carbohydrate phosphorylase DUF4709 PF15821.5 EST49321.1 - 0.00039 20.7 0.2 0.018 15.3 0.0 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4709) SPOB_a PF14689.6 EST49321.1 - 0.079 12.7 0.8 3.5 7.4 0.1 2.6 2 0 0 2 2 2 0 Sensor_kinase_SpoOB-type, alpha-helical domain SKA2 PF16740.5 EST49321.1 - 0.091 12.6 0.1 0.31 10.8 0.1 1.9 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 Hom_end_hint PF05203.16 EST49322.1 - 2.1e-11 44.2 0.0 3.3e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Hom_end-associated Hint SAM_Ste50p PF09235.10 EST49322.1 - 0.14 12.5 0.1 0.44 10.8 0.1 1.9 1 0 0 1 1 1 0 Ste50p, sterile alpha motif FAM153 PF15722.5 EST49323.1 - 0.11 12.8 0.3 0.16 12.4 0.3 1.2 1 0 0 1 1 1 0 FAM153 family VitD-bind_III PF09164.10 EST49323.1 - 0.79 9.8 4.1 9.2 6.3 0.2 2.3 2 0 0 2 2 2 0 Vitamin D binding protein, domain III VESA1_N PF12785.7 EST49325.1 - 0.07 12.1 2.4 0.066 12.2 2.4 1.0 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 DUF2615 PF11027.8 EST49325.1 - 0.078 13.1 4.2 0.19 11.9 4.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2615) Nucleoporin_N PF08801.11 EST49326.1 - 0.031 13.0 1.6 0.35 9.6 0.0 2.8 1 1 3 4 4 4 0 Nup133 N terminal like DUF4820 PF16091.5 EST49327.1 - 0.096 12.0 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) LRR_1 PF00560.33 EST49327.1 - 0.46 11.2 3.3 89 4.3 0.1 3.8 3 1 1 4 4 4 0 Leucine Rich Repeat DASH_Dad2 PF08654.10 EST49328.1 - 0.62 10.5 5.2 1.9 9.0 2.4 2.7 1 1 2 3 3 3 0 DASH complex subunit Dad2 DrrA_P4M PF14860.6 EST49328.1 - 0.62 9.9 7.8 1 9.2 6.4 2.0 1 1 1 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain HeH PF12949.7 EST49329.1 - 0.0053 16.4 0.1 0.091 12.5 0.0 2.8 2 0 0 2 2 2 1 HeH/LEM domain Prefoldin_2 PF01920.20 EST49330.1 - 1.7e-17 63.3 9.3 1.8e-17 63.2 9.3 1.0 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 EST49330.1 - 0.00031 20.6 4.2 0.0084 16.0 0.2 2.1 1 1 1 2 2 2 2 Prefoldin subunit FliJ PF02050.16 EST49330.1 - 0.013 15.7 9.9 0.41 10.9 5.3 2.1 1 1 1 2 2 2 0 Flagellar FliJ protein Spectrin PF00435.21 EST49330.1 - 0.026 15.0 7.2 0.05 14.1 6.7 1.7 1 1 0 1 1 1 0 Spectrin repeat DUF3080 PF11279.8 EST49330.1 - 0.055 12.7 3.3 0.12 11.6 3.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3080) Helo_like_N PF17111.5 EST49330.1 - 0.16 11.3 4.7 2.7 7.3 0.2 2.1 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins Glutaredoxin2_C PF04399.13 EST49330.1 - 0.18 11.7 1.7 9.9 6.0 0.1 2.1 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain Baculo_PEP_C PF04513.12 EST49330.1 - 0.19 11.8 3.1 2.3 8.3 0.1 2.0 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus EURL PF06937.11 EST49330.1 - 0.2 11.0 2.9 0.34 10.3 2.9 1.5 1 1 0 1 1 1 0 EURL protein Exonuc_VII_L PF02601.15 EST49330.1 - 0.23 11.0 2.8 0.25 10.9 2.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF812 PF05667.11 EST49330.1 - 0.35 9.7 7.5 0.47 9.3 7.5 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF812) GOLGA2L5 PF15070.6 EST49330.1 - 0.39 9.3 9.9 0.07 11.8 0.5 2.0 1 1 1 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 bZIP_1 PF00170.21 EST49330.1 - 0.46 10.6 4.4 2.9 8.0 1.7 2.1 2 0 0 2 2 2 0 bZIP transcription factor USP8_interact PF08941.10 EST49330.1 - 0.55 10.0 4.1 0.99 9.2 4.0 1.6 1 1 0 1 1 1 0 USP8 interacting DUF148 PF02520.17 EST49330.1 - 0.61 10.2 7.2 4.9 7.3 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function DUF148 DUF745 PF05335.13 EST49330.1 - 0.69 9.6 5.9 11 5.7 5.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF745) SlyX PF04102.12 EST49330.1 - 4.2 8.1 11.3 26 5.5 0.2 2.7 2 1 0 2 2 2 0 SlyX Sec2p PF06428.11 EST49330.1 - 4.6 7.3 12.6 2 8.5 3.9 2.7 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p TMF_DNA_bd PF12329.8 EST49330.1 - 5.9 7.0 13.2 6.5 6.8 6.9 2.8 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DNA_ligase_A_M PF01068.21 EST49331.1 - 1.1e-52 178.7 0.1 3.4e-52 177.1 0.0 1.8 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EST49331.1 - 8.7e-25 88.0 1.7 8.7e-25 88.0 1.7 1.8 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EST49331.1 - 1e-12 48.5 0.0 2.6e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 EST49331.1 - 7.8e-06 26.3 0.0 1.9e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 RNA ligase ERCC4 PF02732.15 EST49332.1 - 6.9e-07 29.6 0.3 6.9e-07 29.6 0.3 3.3 3 1 1 4 4 4 1 ERCC4 domain GSH_synth_ATP PF03917.17 EST49334.1 - 0.19 10.5 0.0 0.2 10.4 0.0 1.0 1 0 0 1 1 1 0 Eukaryotic glutathione synthase, ATP binding domain RNA_pol_Rpb5_C PF01191.19 EST49336.1 - 0.083 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain ImcF-related_N PF14331.6 EST49339.1 - 0.037 13.4 0.3 0.047 13.0 0.3 1.2 1 0 0 1 1 1 0 ImcF-related N-terminal domain SHIPPO-rpt PF07004.12 EST49339.1 - 0.038 14.9 0.4 4.6 8.3 0.0 3.4 3 0 0 3 3 3 0 Sperm-tail PG-rich repeat HMMR_N PF15905.5 EST49339.1 - 0.11 12.0 2.6 3.7 6.9 0.2 2.5 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal Metallophos PF00149.28 EST49340.1 - 1.8e-12 48.2 0.0 3.5e-12 47.3 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EST49340.1 - 1.6e-08 34.9 0.2 3.6e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 EST49340.1 - 0.13 11.5 0.0 5.4 6.3 0.0 2.7 2 1 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily V-ATPase_G PF03179.15 EST49344.1 - 2.7 8.6 6.3 3.6 8.2 2.1 2.6 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit RRN3 PF05327.11 EST49345.1 - 7.7e-08 31.3 2.0 7.7e-08 31.3 2.0 1.8 1 1 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 MIB_HERC2 PF06701.13 EST49346.1 - 2.9e-13 49.9 2.4 1.2e-08 35.1 0.1 2.9 3 0 0 3 3 3 2 Mib_herc2 CEP170_C PF15308.6 EST49347.1 - 0.6 8.6 3.5 1.1 7.8 3.5 1.3 1 0 0 1 1 1 0 CEP170 C-terminus DUF3902 PF13042.6 EST49349.1 - 0.084 12.5 2.7 0.21 11.1 2.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3902) Pkinase PF00069.25 EST49350.1 - 4e-62 210.0 0.1 4e-62 210.0 0.1 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST49350.1 - 1.7e-29 102.9 0.2 3.4e-29 101.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EST49350.1 - 0.0025 17.8 0.0 1.4 8.8 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EST49350.1 - 0.003 16.9 2.4 0.0037 16.7 0.0 2.3 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 EST49350.1 - 0.0044 16.0 0.2 0.016 14.2 0.0 1.9 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase DUF4162 PF13732.6 EST49350.1 - 0.038 14.7 0.2 15 6.4 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4162) DUF3173 PF11372.8 EST49351.1 - 0.014 15.3 0.1 1.3 9.0 0.0 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3173) CutA1 PF03091.15 EST49351.1 - 0.046 13.6 0.0 0.27 11.1 0.0 2.4 1 0 0 1 1 1 0 CutA1 divalent ion tolerance protein MutS_IV PF05190.18 EST49352.1 - 1.4 9.4 9.5 0.63 10.4 2.7 3.0 2 0 0 2 2 2 0 MutS family domain IV WD40 PF00400.32 EST49353.1 - 3.8e-07 30.7 5.8 0.43 11.5 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EST49353.1 - 5.9e-07 29.7 0.9 0.0064 16.8 0.1 4.9 4 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain HAD_2 PF13419.6 EST49355.1 - 1.1e-20 74.4 0.9 1.3e-20 74.2 0.9 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 EST49355.1 - 1.6e-06 28.6 0.0 2.1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EST49355.1 - 2.3e-06 28.1 0.3 7.1e-05 23.2 0.3 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.18 EST49355.1 - 0.00018 21.3 0.2 0.0014 18.4 0.2 2.1 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase DUF5344 PF17279.2 EST49355.1 - 1.7 9.3 4.5 13 6.5 0.1 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5344) IMPa_helical PF18642.1 EST49356.1 - 0.043 14.2 0.1 0.15 12.5 0.1 1.9 1 0 0 1 1 1 0 Immunomodulating metalloprotease helical domain DUF4359 PF14271.6 EST49356.1 - 0.68 10.7 4.7 2.5 8.9 1.4 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4359) EF-hand_7 PF13499.6 EST49357.1 - 2.7e-06 27.7 1.6 0.036 14.5 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EST49357.1 - 0.00043 20.0 2.4 0.064 13.2 0.3 3.6 3 1 0 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.9 EST49357.1 - 0.025 14.9 0.4 0.72 10.2 0.2 2.1 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Sigma70_r1_1 PF03979.14 EST49357.1 - 0.066 13.3 1.4 2 8.5 0.2 2.2 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 CAF1 PF04857.20 EST49358.1 - 3.1e-14 52.9 0.5 2.8e-06 26.7 0.0 2.6 1 1 1 2 2 2 2 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.20 EST49358.1 - 0.071 12.8 0.0 2.2 8.0 0.0 2.3 2 1 0 2 2 2 0 3'-5' exonuclease DUF3791 PF12668.7 EST49359.1 - 0.073 13.1 0.1 1.8 8.7 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3791) TACC_C PF05010.14 EST49360.1 - 0.034 13.9 28.1 0.04 13.7 22.3 2.9 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF745 PF05335.13 EST49360.1 - 1.2 8.8 21.4 1.7 8.3 11.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) EF-hand_6 PF13405.6 EST49361.1 - 2.3e-08 33.3 8.1 1.2 9.3 0.0 6.9 6 0 0 6 6 6 4 EF-hand domain EF-hand_1 PF00036.32 EST49361.1 - 2.3e-05 23.6 1.1 0.56 9.9 0.0 6.0 6 0 0 6 6 6 1 EF hand EF-hand_7 PF13499.6 EST49361.1 - 2.6e-05 24.6 4.3 0.19 12.2 0.1 5.1 6 0 0 6 6 6 2 EF-hand domain pair SipA_VBS PF17985.1 EST49361.1 - 0.11 12.4 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 SipA vinculin binding site DUF3452 PF11934.8 EST49361.1 - 0.19 11.3 8.0 0.26 10.8 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF3452) HTH_OrfB_IS605 PF12323.8 EST49361.1 - 0.58 9.7 4.3 0.15 11.6 0.2 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Ribosomal_S26e PF01283.19 EST49364.1 - 2.8e-37 127.4 6.9 3e-37 127.3 6.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.7 EST49364.1 - 0.0021 18.6 1.1 0.005 17.4 1.1 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EST49364.1 - 0.0049 17.8 0.7 0.0085 17.0 0.7 1.3 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 EST49364.1 - 0.0076 16.4 0.3 0.14 12.3 0.1 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain DUF5637 PF18687.1 EST49364.1 - 0.035 14.1 0.6 0.063 13.3 0.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5637) Fer4 PF00037.27 EST49364.1 - 0.23 11.3 4.6 0.27 11.1 0.9 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain TIP49 PF06068.13 EST49365.1 - 7.5e-142 472.7 2.9 1e-141 472.3 2.9 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EST49365.1 - 7.3e-20 70.9 0.9 2.2e-19 69.4 0.9 1.9 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 EST49365.1 - 5.1e-10 39.9 0.2 2.6e-06 27.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EST49365.1 - 3.3e-08 33.4 0.3 1.3e-05 25.0 0.0 3.0 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EST49365.1 - 1.7e-06 28.5 0.2 4e-05 24.1 0.2 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EST49365.1 - 5.4e-06 26.7 0.1 0.052 13.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 EST49365.1 - 0.00035 20.6 1.1 0.081 12.9 1.1 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_5 PF07728.14 EST49365.1 - 0.0012 18.8 0.1 0.049 13.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EST49365.1 - 0.0015 18.2 0.1 0.1 12.3 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_7 PF12775.7 EST49365.1 - 0.0025 17.3 0.1 0.0069 15.9 0.0 1.7 2 0 0 2 2 2 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 EST49365.1 - 0.0047 16.3 0.1 0.3 10.5 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EST49365.1 - 0.0061 17.1 0.2 0.032 14.8 0.0 2.4 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EST49365.1 - 0.0092 15.7 0.1 0.03 14.1 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein Parvo_NS1 PF01057.17 EST49365.1 - 0.01 14.9 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_33 PF13671.6 EST49365.1 - 0.013 15.7 0.0 0.03 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 EST49365.1 - 0.014 14.8 0.3 0.29 10.5 0.0 2.5 3 0 0 3 3 3 0 Bacterial TniB protein PhoH PF02562.16 EST49365.1 - 0.014 14.8 1.5 0.024 14.1 0.2 2.0 2 0 0 2 2 2 0 PhoH-like protein DNA_pol3_delta2 PF13177.6 EST49365.1 - 0.015 15.0 0.1 0.045 13.5 0.0 1.7 2 0 0 2 2 2 0 DNA polymerase III, delta subunit AAA_19 PF13245.6 EST49365.1 - 0.018 15.4 1.1 0.68 10.3 1.1 2.6 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 EST49365.1 - 0.026 13.6 2.7 0.4 9.7 0.2 2.5 2 1 1 3 3 3 0 Type II/IV secretion system protein AAA_25 PF13481.6 EST49365.1 - 0.029 13.9 0.1 0.064 12.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EST49365.1 - 0.035 14.0 0.0 0.081 12.8 0.0 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_17 PF13207.6 EST49365.1 - 0.039 14.4 0.8 0.16 12.4 0.4 2.3 2 1 0 2 2 2 0 AAA domain CPT PF07931.12 EST49365.1 - 0.044 13.6 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein APS_kinase PF01583.20 EST49365.1 - 0.077 12.9 0.0 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 Adenylylsulphate kinase TsaE PF02367.17 EST49365.1 - 0.14 12.1 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2570 PF10828.8 EST49368.1 - 4.7 7.1 16.5 35 4.3 15.7 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) DUF1764 PF08576.10 EST49369.1 - 1.4e-20 74.1 3.0 1.7e-20 73.8 3.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF1764) WASH-7_C PF14746.6 EST49369.1 - 0.057 13.1 0.2 0.09 12.5 0.2 1.3 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal Peptidase_C28 PF05408.11 EST49371.1 - 0.012 15.4 0.3 0.041 13.6 0.1 1.7 2 0 0 2 2 2 0 Foot-and-mouth virus L-proteinase YlbD_coat PF14071.6 EST49373.1 - 0.76 10.0 6.4 1.7 8.9 1.0 2.2 1 1 1 2 2 2 0 Putative coat protein AMPK1_CBM PF16561.5 EST49374.1 - 3.7e-25 87.9 0.6 9.9e-25 86.6 0.6 1.7 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 EST49374.1 - 5.5e-16 58.6 1.9 1.4e-15 57.3 1.9 1.7 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM_48 PF02922.18 EST49374.1 - 3.7e-05 24.0 0.2 0.00038 20.7 0.0 2.5 3 0 0 3 3 3 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) CBM53 PF16760.5 EST49374.1 - 0.012 16.2 0.3 0.028 15.0 0.3 1.6 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) PQQ_3 PF13570.6 EST49375.1 - 0.23 12.0 0.0 5.9 7.5 0.0 3.2 4 0 0 4 4 4 0 PQQ-like domain zf-RING_2 PF13639.6 EST49376.1 - 5.1e-10 39.5 9.3 9.7e-10 38.6 9.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EST49376.1 - 6e-07 29.2 9.4 1.4e-06 28.1 9.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EST49376.1 - 2.2e-06 27.9 9.8 2.2e-06 27.9 9.8 2.1 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EST49376.1 - 6.9e-06 26.0 5.4 1.2e-05 25.2 3.1 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EST49376.1 - 8.9e-06 25.5 10.0 2e-05 24.3 10.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EST49376.1 - 1.1e-05 25.1 6.9 1.1e-05 25.1 6.9 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 EST49376.1 - 2.2e-05 24.2 7.1 4.3e-05 23.3 7.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EST49376.1 - 0.00024 20.7 6.7 0.00049 19.7 6.7 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 EST49376.1 - 0.001 19.1 5.4 0.0032 17.5 5.4 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EST49376.1 - 0.0013 18.6 8.2 0.0032 17.4 8.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain TerY_C PF15616.6 EST49376.1 - 0.0099 16.0 5.3 0.031 14.4 5.3 1.9 1 1 0 1 1 1 1 TerY-C metal binding domain DUF3888 PF13027.6 EST49376.1 - 0.029 14.8 1.9 0.23 11.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3888) zf-RING_10 PF16685.5 EST49376.1 - 0.03 14.5 5.6 0.03 14.5 5.6 2.0 2 0 0 2 2 1 0 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 EST49376.1 - 0.048 13.5 8.1 0.13 12.2 8.0 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 DUF2072 PF09845.9 EST49376.1 - 0.053 13.8 11.3 3.9 7.7 11.3 2.3 1 1 0 1 1 1 0 Zn-ribbon containing protein zf-Nse PF11789.8 EST49376.1 - 0.053 13.3 5.4 0.073 12.9 3.7 2.2 2 0 0 2 2 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 EST49376.1 - 0.12 12.5 6.9 0.39 10.9 6.9 1.9 1 1 0 1 1 1 0 RING-variant domain zf-RING_6 PF14835.6 EST49376.1 - 0.2 11.5 5.5 0.37 10.7 1.7 2.4 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-UDP PF14569.6 EST49376.1 - 0.52 10.5 7.6 0.15 12.2 3.5 2.1 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-C3HC4_4 PF15227.6 EST49376.1 - 1.2 9.4 8.6 4 7.7 8.6 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 EST49376.1 - 1.9 8.7 9.1 22 5.3 9.1 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 EST49376.1 - 9.2 6.4 9.3 28 4.9 8.5 2.2 2 1 0 2 2 1 0 Zinc-finger Rpr2 PF04032.16 EST49377.1 - 0.0038 17.5 13.4 0.0096 16.2 13.4 1.7 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Transpos_assoc PF13963.6 EST49377.1 - 2.9 8.3 15.1 2.6 8.4 6.5 2.8 1 1 2 3 3 3 0 Transposase-associated domain zf-C2H2 PF00096.26 EST49378.1 - 1.9e-32 109.9 46.0 3.4e-06 27.2 3.2 6.4 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EST49378.1 - 3.3e-28 95.9 43.8 7.7e-05 23.2 2.5 6.4 6 0 0 6 6 6 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EST49378.1 - 2e-20 72.2 38.7 6.2e-07 29.6 0.3 7.9 8 0 0 8 8 8 5 Zinc-finger double domain zf-met PF12874.7 EST49378.1 - 1.1e-11 44.7 37.9 0.0027 18.0 1.6 7.1 7 0 0 7 7 6 5 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EST49378.1 - 3.3e-10 40.0 43.6 0.019 15.2 0.5 7.5 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 EST49378.1 - 2.6e-08 34.0 32.4 9.5e-06 25.8 4.5 4.7 2 1 1 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 EST49378.1 - 2.3e-07 31.1 39.3 0.13 12.6 11.3 5.8 1 1 3 5 5 5 4 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 EST49378.1 - 7.3e-05 22.5 11.6 0.072 12.9 0.2 5.3 1 1 4 5 5 5 1 C2H2 type zinc-finger (1 copy) zf-C2H2_3rep PF18868.1 EST49378.1 - 0.00075 20.2 28.5 0.34 11.6 1.5 5.0 2 1 1 3 3 3 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_8 PF15909.5 EST49378.1 - 0.0014 18.9 18.4 0.011 16.0 5.5 2.8 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-C2HC_2 PF13913.6 EST49378.1 - 0.0022 17.8 29.1 0.096 12.6 0.7 5.8 6 0 0 6 6 5 3 zinc-finger of a C2HC-type Zn-C2H2_12 PF18112.1 EST49378.1 - 0.0081 16.6 5.9 0.014 15.9 2.8 5.6 5 0 0 5 5 5 2 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_6 PF13912.6 EST49378.1 - 0.009 16.0 4.3 0.025 14.6 2.2 7.0 7 0 0 7 7 7 2 C2H2-type zinc finger zf-BED PF02892.15 EST49378.1 - 0.011 15.8 34.2 0.12 12.4 1.0 6.4 2 1 4 6 6 6 0 BED zinc finger zinc_ribbon_9 PF14369.6 EST49378.1 - 0.011 15.9 19.6 2.6 8.4 0.0 5.8 6 0 0 6 6 6 0 zinc-ribbon Prok-RING_1 PF14446.6 EST49378.1 - 0.016 15.1 20.6 6.6 6.7 0.1 6.1 6 0 0 6 6 6 0 Prokaryotic RING finger family 1 zf_UBZ PF18439.1 EST49378.1 - 0.017 14.7 27.4 0.72 9.5 0.8 6.2 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger Elf1 PF05129.13 EST49378.1 - 0.019 15.0 24.9 0.075 13.1 6.9 4.9 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like HypA PF01155.19 EST49378.1 - 0.02 14.9 0.6 0.02 14.9 0.6 3.8 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA BolA PF01722.18 EST49378.1 - 0.021 15.1 11.1 0.77 10.1 4.5 4.1 2 1 0 2 2 2 0 BolA-like protein PyrI_C PF02748.15 EST49378.1 - 0.036 14.0 19.2 0.067 13.1 0.2 5.4 4 1 1 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain GAGA PF09237.11 EST49378.1 - 0.077 12.8 8.9 0.41 10.5 1.1 3.7 1 1 2 3 3 3 0 GAGA factor DUF2225 PF09986.9 EST49378.1 - 0.094 12.4 18.5 0.28 10.9 0.1 4.5 2 1 3 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2225) Prok-RING_4 PF14447.6 EST49378.1 - 0.099 12.5 18.8 0.81 9.6 5.3 4.7 5 1 0 5 5 5 0 Prokaryotic RING finger family 4 zf-MIZ PF02891.20 EST49378.1 - 0.15 11.8 19.6 0.35 10.6 8.3 3.7 5 0 0 5 5 3 0 MIZ/SP-RING zinc finger zf-C2H2_11 PF16622.5 EST49378.1 - 0.21 11.4 25.6 0.78 9.6 0.6 5.0 4 0 0 4 4 4 0 zinc-finger C2H2-type UBZ_FAAP20 PF15750.5 EST49378.1 - 0.22 11.5 0.3 0.22 11.5 0.3 4.2 5 0 0 5 5 4 0 Ubiquitin-binding zinc-finger Trm112p PF03966.16 EST49378.1 - 0.26 11.9 4.1 3.4 8.3 0.3 2.8 3 0 0 3 3 2 0 Trm112p-like protein zinc_ribbon_15 PF17032.5 EST49378.1 - 0.27 12.0 27.8 0.47 11.2 0.9 4.0 1 1 3 4 4 4 0 zinc-ribbon family zf-Sec23_Sec24 PF04810.15 EST49378.1 - 0.27 11.3 24.8 15 5.8 0.3 6.2 6 0 0 6 6 6 0 Sec23/Sec24 zinc finger zf_C2H2_10 PF18414.1 EST49378.1 - 0.29 10.7 5.6 3.2 7.4 0.0 3.5 3 0 0 3 3 3 0 C2H2 type zinc-finger Zn-ribbon_8 PF09723.10 EST49378.1 - 0.42 10.8 29.3 1.1 9.4 3.7 5.0 2 1 4 6 6 6 0 Zinc ribbon domain C1_4 PF07975.12 EST49378.1 - 1 9.7 28.9 4.5 7.6 2.9 5.1 2 1 2 5 5 5 0 TFIIH C1-like domain Rad50_zn_hook PF04423.14 EST49378.1 - 1.1 9.2 6.8 23 4.9 0.1 3.9 3 1 1 4 4 4 0 Rad50 zinc hook motif MFMR_assoc PF16596.5 EST49378.1 - 1.6 9.2 8.7 2.1 8.8 8.3 1.4 1 1 0 1 1 1 0 Disordered region downstream of MFMR zinc-ribbons_6 PF07191.12 EST49378.1 - 1.7 8.7 29.6 1.1 9.3 3.4 5.1 2 1 2 4 4 4 0 zinc-ribbons LIM PF00412.22 EST49378.1 - 2.8 8.2 30.3 31 4.9 3.8 5.2 2 1 3 5 5 5 0 LIM domain DUF2256 PF10013.9 EST49378.1 - 6.7 6.9 19.0 17 5.6 0.1 5.7 6 0 0 6 6 5 0 Uncharacterized protein conserved in bacteria (DUF2256) RPN2_C PF18004.1 EST49378.1 - 7.2 6.5 10.3 0.42 10.5 0.2 2.2 1 1 1 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain B9-C2 PF07162.11 EST49379.1 - 1.3e-23 84.0 1.1 2.4e-23 83.2 1.1 1.5 1 1 0 1 1 1 1 Ciliary basal body-associated, B9 protein DUF4250 PF14056.6 EST49380.1 - 0.014 15.3 0.5 0.031 14.2 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) Seryl_tRNA_N PF02403.22 EST49380.1 - 0.015 15.5 4.6 0.05 13.8 4.6 1.9 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Methyltransf_28 PF02636.17 EST49380.1 - 0.018 14.7 0.1 0.018 14.7 0.1 2.6 2 1 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF1664 PF07889.12 EST49380.1 - 0.23 11.5 2.6 0.68 10.0 2.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) YabA PF06156.13 EST49380.1 - 6.6 7.4 8.1 3.4 8.4 4.5 2.5 1 1 1 2 2 2 0 Initiation control protein YabA PHD PF00628.29 EST49381.1 - 5.7e-05 22.9 7.1 0.00012 21.9 7.1 1.6 1 0 0 1 1 1 1 PHD-finger RE_ApaLI PF09499.10 EST49381.1 - 0.0085 15.8 0.1 0.016 14.9 0.1 1.4 1 0 0 1 1 1 1 ApaLI-like restriction endonuclease Filament PF00038.21 EST49381.1 - 0.18 11.4 6.6 2.3 7.7 1.1 2.2 2 0 0 2 2 2 0 Intermediate filament protein DUF3447 PF11929.8 EST49382.1 - 0.023 14.6 0.1 0.047 13.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3447) SOBP PF15279.6 EST49383.1 - 2.5 8.6 17.5 2.9 8.4 17.5 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein Neur_chan_memb PF02932.16 EST49383.1 - 5.2 7.1 6.8 6.2 6.8 6.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.13 EST49383.1 - 6 6.8 26.5 6.6 6.6 26.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_M14 PF00246.24 EST49386.1 - 8.2e-19 68.5 0.0 1.5e-18 67.6 0.0 1.5 1 0 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 EST49386.1 - 9.8e-08 32.3 1.3 9.8e-07 29.1 1.3 2.5 1 1 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain PA28_beta PF02252.18 EST49389.1 - 2.5e-08 33.7 2.4 2.5e-08 33.7 2.4 1.7 2 0 0 2 2 2 1 Proteasome activator pa28 beta subunit Paramyxo_P PF01806.17 EST49389.1 - 0.034 13.6 0.2 0.034 13.6 0.2 1.5 2 0 0 2 2 2 0 Paramyxovirinae P phosphoprotein C-terminal region DUF4962 PF16332.5 EST49389.1 - 0.15 10.6 5.1 0.012 14.1 0.6 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4962) Nudix_hydro PF18290.1 EST49389.1 - 1.3 9.1 4.2 0.44 10.6 0.8 1.9 2 1 0 2 2 2 0 Nudix hydrolase domain DUF2605 PF10792.9 EST49389.1 - 1.6 8.7 7.5 0.39 10.7 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2605) SHIPPO-rpt PF07004.12 EST49390.1 - 3.9e-31 106.5 33.3 4.4e-05 24.2 0.3 6.1 6 0 0 6 6 6 6 Sperm-tail PG-rich repeat ECR1_N PF14382.6 EST49390.1 - 2.4e-05 24.0 1.5 15 5.5 0.0 5.7 6 0 0 6 6 6 3 Exosome complex exonuclease RRP4 N-terminal region Peptidase_S77 PF03420.13 EST49391.1 - 0.25 11.0 0.8 0.58 9.8 0.8 1.6 1 0 0 1 1 1 0 Prohead core protein serine protease Ras PF00071.22 EST49393.1 - 4.1e-52 176.1 2.5 5.2e-52 175.7 2.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EST49393.1 - 2.1e-30 105.4 0.9 3.6e-30 104.6 0.9 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EST49393.1 - 9.2e-14 51.3 0.2 1.2e-13 50.9 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EST49393.1 - 9.1e-06 25.7 0.1 1.6e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EST49393.1 - 3.3e-05 23.4 0.2 4.1e-05 23.0 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EST49393.1 - 0.0023 17.9 0.6 0.43 10.5 0.2 2.4 1 1 1 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 EST49393.1 - 0.031 14.3 0.3 2.4 8.2 0.0 2.5 1 1 1 2 2 2 0 Dynamin family Toxin_R_bind_C PF07951.12 EST49393.1 - 0.068 12.8 0.7 0.4 10.3 0.7 2.0 1 1 0 1 1 1 0 Clostridium neurotoxin, C-terminal receptor binding Sec20 PF03908.13 EST49394.1 - 3.1e-08 33.4 1.8 6.3e-08 32.4 0.2 1.9 1 1 1 2 2 2 1 Sec20 Tsg PF04668.12 EST49394.1 - 0.11 13.2 0.2 0.15 12.7 0.2 1.2 1 0 0 1 1 1 0 Twisted gastrulation (Tsg) protein conserved region Hit1_C PF18268.1 EST49396.1 - 0.021 15.0 0.5 0.37 11.0 0.1 3.2 3 0 0 3 3 3 0 Hit1 C-terminal MRFAP1 PF15155.6 EST49397.1 - 0.099 13.2 1.3 21 5.7 0.1 2.8 2 0 0 2 2 2 0 MORF4 family-associated protein1 DUF5635 PF18685.1 EST49397.1 - 2.7 8.0 9.4 4.2 7.4 1.3 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5635) CT_C_D PF02682.16 EST49397.1 - 6.7 6.4 11.5 1.6 8.4 0.6 3.7 3 1 0 3 3 3 0 Carboxyltransferase domain, subdomain C and D PEX-1N PF09262.11 EST49397.1 - 8.2 6.9 22.6 0.23 11.9 0.3 4.4 4 2 0 4 4 4 0 Peroxisome biogenesis factor 1, N-terminal R-HINP1I PF11463.8 EST49398.1 - 0.00036 20.1 0.2 0.00036 20.1 0.2 1.9 2 1 0 2 2 2 1 R.HinP1I restriction endonuclease Carbam_trans_N PF02543.15 EST49398.1 - 0.022 14.4 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus FHA PF00498.26 EST49399.1 - 1.2e-05 25.6 0.5 4.9e-05 23.6 0.4 2.2 2 0 0 2 2 2 1 FHA domain RTT107_BRCT_5 PF16770.5 EST49399.1 - 0.0083 16.0 1.5 0.015 15.1 0.0 2.3 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain PseudoU_synth_1 PF01416.20 EST49401.1 - 3.1e-21 75.8 0.0 9.5e-20 71.1 0.0 2.3 2 0 0 2 2 2 1 tRNA pseudouridine synthase zf-DBF PF07535.12 EST49402.1 - 0.0044 17.1 1.0 0.025 14.7 1.0 2.4 1 0 0 1 1 1 1 DBF zinc finger Nop PF01798.18 EST49402.1 - 3.2 7.2 10.1 0.08 12.4 0.3 2.9 3 0 0 3 3 3 0 snoRNA binding domain, fibrillarin PT PF04886.12 EST49402.1 - 4.9 6.8 7.8 0.42 10.2 1.3 2.3 2 0 0 2 2 2 0 PT repeat TLD PF07534.16 EST49403.1 - 6.9e-10 39.3 1.4 6.9e-10 39.3 1.4 2.4 2 1 1 3 3 3 1 TLD TBK1_ULD PF18396.1 EST49403.1 - 0.0014 18.6 1.4 0.0014 18.6 1.4 2.6 3 0 0 3 3 3 1 TANK binding kinase 1 ubiquitin-like domain Peptidase_C28 PF05408.11 EST49403.1 - 0.14 11.9 0.4 2.2 7.9 0.1 2.3 2 0 0 2 2 2 0 Foot-and-mouth virus L-proteinase WPP PF13943.6 EST49405.1 - 0.03 14.7 0.0 0.038 14.4 0.0 1.1 1 0 0 1 1 1 0 WPP domain UBA_2 PF08587.11 EST49407.1 - 0.13 12.3 4.0 0.14 12.3 0.3 2.8 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) Methyltransf_16 PF10294.9 EST49408.1 - 5.5e-11 42.5 0.2 1.6e-08 34.5 0.1 2.5 1 1 2 3 3 3 2 Lysine methyltransferase Methyltransf_23 PF13489.6 EST49408.1 - 0.00029 20.7 0.0 0.00057 19.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EST49408.1 - 0.013 15.1 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Ribosomal_S8 PF00410.19 EST49409.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S8 PseudoU_synth_1 PF01416.20 EST49410.1 - 1.3e-18 67.4 0.0 3.7e-16 59.5 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase HALZ PF02183.18 EST49411.1 - 0.33 11.2 0.1 0.33 11.2 0.1 6.6 5 1 1 6 6 6 0 Homeobox associated leucine zipper FUSC PF04632.12 EST49411.1 - 0.41 9.1 13.3 0.21 10.1 1.7 2.6 2 1 1 3 3 3 0 Fusaric acid resistance protein family Myb_DNA-bind_3 PF12776.7 EST49411.1 - 0.51 11.3 0.1 0.51 11.3 0.1 4.5 2 2 2 5 5 5 0 Myb/SANT-like DNA-binding domain Ank_2 PF12796.7 EST49412.1 - 5.2e-15 55.8 6.2 6.4e-05 23.5 0.0 7.0 7 0 0 7 7 7 3 Ankyrin repeats (3 copies) Ank PF00023.30 EST49412.1 - 7.3e-07 29.4 5.3 5.5 7.6 0.3 6.4 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 EST49412.1 - 2.9e-06 27.4 0.0 35 4.9 0.0 6.9 6 0 0 6 6 6 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EST49412.1 - 3.8e-06 27.3 3.2 0.12 13.0 0.0 6.0 7 0 0 7 7 7 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EST49412.1 - 8.7e-06 25.7 6.9 1.2 9.9 0.1 6.7 7 0 0 7 7 7 3 Ankyrin repeat Glyco_hydro_77 PF02446.17 EST49413.1 - 5.9e-117 391.4 7.9 8e-117 390.9 7.9 1.1 1 0 0 1 1 1 1 4-alpha-glucanotransferase CBM_20 PF00686.19 EST49413.1 - 1.9e-11 43.7 1.6 1.8e-07 30.9 0.0 3.3 3 0 0 3 3 3 2 Starch binding domain Integrase_H2C2 PF17921.1 EST49413.1 - 0.12 12.5 6.6 2 8.6 0.2 2.7 2 0 0 2 2 2 0 Integrase zinc binding domain MLTD_N PF06474.12 EST49417.1 - 1.1 9.5 5.0 9.3 6.5 0.5 2.4 2 0 0 2 2 2 0 MltD lipid attachment motif DUF3043 PF11241.8 EST49420.1 - 0.76 9.8 1.5 0.92 9.5 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Microcin PF03526.13 EST49422.1 - 0.1 12.4 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 Colicin E1 (microcin) immunity protein Pkinase PF00069.25 EST49424.1 - 6.7e-66 222.4 0.3 1.2e-65 221.6 0.3 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EST49424.1 - 4.5e-41 140.8 0.2 9.2e-41 139.8 0.2 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EST49424.1 - 0.058 12.2 0.0 0.058 12.2 0.0 2.7 3 0 0 3 3 3 0 Fungal protein kinase DUF3455 PF11937.8 EST49426.1 - 0.089 13.2 0.2 0.73 10.2 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3455) Kinesin PF00225.23 EST49427.1 - 1.4e-112 375.9 0.9 1.4e-112 375.9 0.9 3.0 2 1 1 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 EST49427.1 - 1.4e-24 86.8 0.3 1.4e-24 86.8 0.3 2.9 2 1 0 2 2 2 1 Microtubule binding BST2 PF16716.5 EST49427.1 - 0.083 13.5 0.4 0.083 13.5 0.4 4.4 2 1 2 4 4 4 0 Bone marrow stromal antigen 2 Adipogenin PF15202.6 EST49428.1 - 0.1 12.7 0.1 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 Adipogenin RRM_3 PF08777.11 EST49432.1 - 1.9e-15 56.7 0.8 3.2e-15 56.0 0.3 1.5 2 0 0 2 2 2 1 RNA binding motif RRM_1 PF00076.22 EST49432.1 - 0.05 13.4 0.1 0.089 12.6 0.1 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_9 PF12781.7 EST49434.1 - 3.2e-67 225.9 7.8 1.6e-66 223.6 8.5 1.8 2 0 0 2 2 2 1 ATP-binding dynein motor region Dynein_heavy PF03028.15 EST49434.1 - 3.4e-16 59.4 0.0 9.7e-13 48.3 0.0 2.7 2 0 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain Dynein_C PF18199.1 EST49435.1 - 2.8e-90 302.7 0.2 3.8e-90 302.2 0.2 1.2 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 EST49435.1 - 3e-46 157.2 0.2 5.1e-46 156.5 0.2 1.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain DUF956 PF06115.11 EST49435.1 - 0.11 12.2 0.0 0.35 10.6 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF956) Lipase_3 PF01764.25 EST49436.1 - 0.023 14.5 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) zf-C2H2_12 PF18658.1 EST49437.1 - 0.2 11.2 1.0 4.3 7.0 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger C2H2-type Pox_A_type_inc PF04508.12 EST49437.1 - 0.74 9.8 3.4 1.4 8.9 0.2 3.2 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat DUF695 PF05117.12 EST49437.1 - 3.5 7.8 8.3 2.6 8.2 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF695) YkyA PF10368.9 EST49438.1 - 0.006 16.3 1.8 0.0074 16.0 1.8 1.1 1 0 0 1 1 1 1 Putative cell-wall binding lipoprotein DUF4446 PF14584.6 EST49438.1 - 0.0064 16.5 0.1 0.0071 16.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4446) Laminin_II PF06009.12 EST49438.1 - 0.02 14.9 0.3 0.023 14.7 0.3 1.1 1 0 0 1 1 1 0 Laminin Domain II DUF1664 PF07889.12 EST49438.1 - 0.04 14.0 1.1 0.054 13.5 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) COG2 PF06148.11 EST49438.1 - 0.048 13.7 0.3 0.057 13.5 0.3 1.1 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 SNARE PF05739.19 EST49438.1 - 0.099 12.7 0.1 0.099 12.7 0.1 2.2 3 0 0 3 3 3 0 SNARE domain TolA_bind_tri PF16331.5 EST49438.1 - 0.14 12.3 4.7 1 9.5 4.7 2.1 1 1 0 1 1 1 0 TolA binding protein trimerisation YqjK PF13997.6 EST49438.1 - 0.15 12.4 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 YqjK-like protein DUF349 PF03993.12 EST49438.1 - 0.17 12.2 1.9 0.23 11.8 1.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) TPR_2 PF07719.17 EST49439.1 - 0.0014 18.6 0.3 1.2 9.4 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EST49439.1 - 0.033 14.5 0.4 10 6.5 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EST49440.1 - 0.0017 18.3 0.3 1.2 9.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EST49440.1 - 0.03 14.6 0.3 9.5 6.6 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EST49440.1 - 0.26 12.0 0.9 5.4 7.9 0.2 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat YkyA PF10368.9 EST49441.1 - 0.006 16.3 1.8 0.0074 16.0 1.8 1.1 1 0 0 1 1 1 1 Putative cell-wall binding lipoprotein DUF4446 PF14584.6 EST49441.1 - 0.0064 16.5 0.1 0.0071 16.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4446) Laminin_II PF06009.12 EST49441.1 - 0.02 14.9 0.3 0.023 14.7 0.3 1.1 1 0 0 1 1 1 0 Laminin Domain II DUF1664 PF07889.12 EST49441.1 - 0.04 14.0 1.1 0.054 13.5 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) COG2 PF06148.11 EST49441.1 - 0.048 13.7 0.3 0.057 13.5 0.3 1.1 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 SNARE PF05739.19 EST49441.1 - 0.099 12.7 0.1 0.099 12.7 0.1 2.2 3 0 0 3 3 3 0 SNARE domain TolA_bind_tri PF16331.5 EST49441.1 - 0.14 12.3 4.7 1 9.5 4.7 2.1 1 1 0 1 1 1 0 TolA binding protein trimerisation YqjK PF13997.6 EST49441.1 - 0.15 12.4 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 YqjK-like protein DUF349 PF03993.12 EST49441.1 - 0.17 12.2 1.9 0.23 11.8 1.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) EcoEI_R_C PF08463.10 EST49442.1 - 0.034 14.3 0.6 0.036 14.2 0.6 1.1 1 0 0 1 1 1 0 EcoEI R protein C-terminal ProRS-C_2 PF09181.10 EST49442.1 - 0.093 12.9 0.1 0.17 12.0 0.1 1.5 1 1 0 1 1 1 0 Prolyl-tRNA synthetase, C-terminal MMR_HSR1 PF01926.23 EST49443.1 - 0.0012 18.9 0.3 0.0044 17.1 0.1 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 EST49443.1 - 0.021 15.0 0.1 0.05 13.8 0.1 1.7 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 EST49443.1 - 0.043 14.1 0.0 0.057 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EST49443.1 - 0.052 13.3 0.0 0.052 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EST49443.1 - 0.066 13.6 0.2 0.12 12.8 0.2 1.6 1 1 0 1 1 1 0 RNA helicase Ras PF00071.22 EST49443.1 - 0.073 12.7 0.1 0.14 11.8 0.1 1.5 1 1 0 1 1 1 0 Ras family AAA_22 PF13401.6 EST49443.1 - 0.14 12.4 0.0 0.15 12.3 0.0 1.3 1 1 0 1 1 1 0 AAA domain Kinesin PF00225.23 EST49446.1 - 1.8e-101 339.4 0.0 1.8e-101 339.4 0.0 2.8 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 EST49446.1 - 1.2e-23 83.7 0.0 1.2e-23 83.7 0.0 3.3 2 1 0 2 2 2 1 Microtubule binding WBS_methylT PF12589.8 EST49447.1 - 7.6e-09 36.2 4.2 1.2e-08 35.6 4.2 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 EST49447.1 - 1.4e-08 35.2 0.0 3.6e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EST49447.1 - 1e-05 25.5 0.0 2.8e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EST49447.1 - 4.1e-05 24.2 0.0 0.0001 23.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EST49447.1 - 0.012 14.9 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PCMT PF01135.19 EST49447.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 EST49447.1 - 0.13 13.0 0.1 0.42 11.4 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain TGT PF01702.18 EST49448.1 - 1.6e-118 395.9 0.0 2e-118 395.6 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Topoisom_bac PF01131.20 EST49449.1 - 2.1e-105 353.1 0.9 2.8e-105 352.7 0.9 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 EST49449.1 - 6.2e-15 55.3 0.5 2.5e-14 53.3 0.0 2.3 3 0 0 3 3 3 1 Toprim domain Toprim_2 PF13155.6 EST49449.1 - 0.007 16.8 0.0 0.024 15.1 0.0 1.9 1 0 0 1 1 1 1 Toprim-like Toprim_4 PF13662.6 EST49449.1 - 0.048 14.1 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 Toprim domain CutC PF03932.14 EST49450.1 - 0.075 12.5 0.0 0.082 12.4 0.0 1.1 1 0 0 1 1 1 0 CutC family Histone PF00125.24 EST49451.1 - 7.6e-09 36.0 1.5 1.5e-08 35.1 1.5 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EST49451.1 - 0.0014 18.9 0.2 0.0027 18.0 0.2 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Lambda_Kil PF06301.11 EST49451.1 - 0.029 14.0 0.0 0.053 13.1 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage lambda Kil protein ANAPC4_WD40 PF12894.7 EST49452.1 - 2.7e-07 30.8 0.8 0.041 14.2 0.1 4.8 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EST49452.1 - 0.00017 22.3 1.2 0.45 11.5 0.1 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 EST49452.1 - 0.00054 19.1 1.3 0.0027 16.8 1.2 1.9 1 1 1 2 2 2 1 Coatomer WD associated region TFIIA PF03153.13 EST49453.1 - 0.0048 16.9 22.7 0.0061 16.6 22.7 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DHHA1 PF02272.19 EST49453.1 - 0.019 15.4 0.5 0.019 15.4 0.5 3.2 2 2 2 4 4 4 0 DHHA1 domain BPL_N PF09825.9 EST49453.1 - 0.055 12.5 13.9 0.49 9.4 13.3 2.1 2 0 0 2 2 2 0 Biotin-protein ligase, N terminal TcpQ PF10671.9 EST49453.1 - 0.2 11.8 1.7 1 9.6 0.1 3.0 3 0 0 3 3 3 0 Toxin co-regulated pilus biosynthesis protein Q Prominin PF05478.11 EST49453.1 - 0.48 8.3 23.2 0.85 7.5 23.2 1.4 1 0 0 1 1 1 0 Prominin DUF1664 PF07889.12 EST49453.1 - 1.3 9.0 17.5 0.23 11.5 2.6 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) DUF3837 PF12939.7 EST49453.1 - 4.6 7.7 13.0 1.4 9.4 0.7 4.2 3 1 0 4 4 4 0 Domain of unknown function (DUF3837) NHL PF01436.21 EST49454.1 - 2.4e-13 49.4 0.2 0.02 14.9 0.0 5.9 5 1 0 5 5 5 4 NHL repeat Calycin_like PF13944.6 EST49454.1 - 0.095 13.0 0.3 0.095 13.0 0.3 2.7 2 1 1 3 3 3 0 Calycin-like beta-barrel domain Ceramidse_alk_C PF17048.5 EST49455.1 - 0.048 13.5 0.0 0.069 13.0 0.0 1.2 1 0 0 1 1 1 0 Neutral/alkaline non-lysosomal ceramidase, C-terminal EzrA PF06160.12 EST49455.1 - 0.23 9.6 7.5 0.29 9.3 7.5 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF2408 PF10303.9 EST49455.1 - 0.36 11.4 4.3 0.93 10.1 4.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) FapA PF03961.13 EST49455.1 - 0.46 9.0 4.2 0.5 8.9 4.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Rhodanese PF00581.20 EST49456.1 - 8.3e-10 39.1 0.0 1.4e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain RVT_N PF13655.6 EST49457.1 - 0.074 13.3 0.5 12 6.3 0.1 2.3 2 0 0 2 2 2 0 N-terminal domain of reverse transcriptase SNF2_N PF00176.23 EST49457.1 - 0.25 10.0 2.1 0.48 9.1 0.2 1.9 1 1 0 2 2 2 0 SNF2 family N-terminal domain NuDC PF16273.5 EST49457.1 - 0.76 10.4 3.2 20 5.8 0.1 2.3 2 0 0 2 2 2 0 Nuclear distribution C domain Colicin_Pyocin PF01320.18 EST49458.1 - 0.07 13.2 0.7 0.37 10.9 0.6 2.3 1 1 0 1 1 1 0 Colicin immunity protein / pyocin immunity protein gpW PF02831.15 EST49458.1 - 0.19 11.7 0.5 0.48 10.4 0.5 1.7 1 0 0 1 1 1 0 gpW N6_N4_Mtase PF01555.18 EST49458.1 - 0.51 10.0 5.0 0.49 10.1 4.1 1.4 1 1 0 1 1 1 0 DNA methylase THF_DHG_CYH PF00763.23 EST49458.1 - 1.5 9.1 11.5 4.3 7.7 3.2 2.2 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Peptidase_M29 PF02073.15 EST49459.1 - 4e-09 35.8 0.0 0.0059 15.4 0.0 3.1 3 0 0 3 3 3 2 Thermophilic metalloprotease (M29) DUF2661 PF10860.8 EST49459.1 - 0.065 13.3 0.7 0.15 12.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2661) PHP_C PF13263.6 EST49460.1 - 0.00016 21.4 0.0 0.00032 20.4 0.0 1.5 1 0 0 1 1 1 1 PHP-associated PHP PF02811.19 EST49460.1 - 0.00022 21.5 0.6 0.00034 20.9 0.6 1.4 1 1 0 1 1 1 1 PHP domain SEP PF08059.13 EST49461.1 - 5.4e-11 42.9 0.0 1.5e-10 41.5 0.0 1.8 1 0 0 1 1 1 1 SEP domain TPR_22 PF18833.1 EST49461.1 - 0.039 14.1 1.2 0.13 12.4 1.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Phage_GP20 PF06810.11 EST49461.1 - 3.4 7.5 9.3 0.41 10.5 0.5 3.1 2 2 1 3 3 3 0 Phage minor structural protein GP20 FHA PF00498.26 EST49462.1 - 6.2e-14 52.1 0.9 1.8e-13 50.6 0.2 2.2 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 EST49462.1 - 8.7e-06 26.0 1.7 2.7e-05 24.4 0.0 2.7 3 0 0 3 3 3 1 Inner membrane component of T3SS, cytoplasmic domain SIX1_SD PF16878.5 EST49462.1 - 0.0019 18.7 0.3 0.0019 18.7 0.3 3.8 4 1 0 4 4 4 1 Transcriptional regulator, SIX1, N-terminal SD domain RVT_1 PF00078.27 EST49463.1 - 0.022 14.3 0.9 0.049 13.1 0.2 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2024 PF09630.10 EST49463.1 - 0.023 14.6 0.3 0.054 13.4 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2024) Fe_hyd_lg_C PF02906.14 EST49464.1 - 9.8e-11 41.8 1.3 5.3e-10 39.4 0.2 2.6 2 1 0 2 2 2 1 Iron only hydrogenase large subunit, C-terminal domain RPW8 PF05659.11 EST49464.1 - 0.094 12.4 2.1 0.23 11.1 2.1 1.7 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 TBCC PF07986.12 EST49466.1 - 1.4e-21 76.4 3.3 1.4e-21 76.4 3.3 1.7 2 0 0 2 2 2 1 Tubulin binding cofactor C DEAD PF00270.29 EST49466.1 - 0.0061 16.3 1.4 0.011 15.5 0.4 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF3387 PF11867.8 EST49466.1 - 0.009 15.4 0.2 0.014 14.8 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3387) CAP_C PF08603.11 EST49466.1 - 0.5 10.0 7.2 0.18 11.4 3.6 2.0 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) C terminal HIPIP PF01355.17 EST49466.1 - 4.5 7.7 6.8 12 6.3 0.9 2.8 2 1 1 3 3 3 0 High potential iron-sulfur protein Macro PF01661.21 EST49467.1 - 7e-13 48.7 0.0 1.3e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Macro domain NDUFB10 PF10249.9 EST49468.1 - 0.038 14.5 0.6 0.062 13.8 0.6 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 BCIP PF13862.6 EST49469.1 - 3.4e-12 46.6 1.9 1.5e-11 44.5 1.9 1.8 1 1 0 1 1 1 1 p21-C-terminal region-binding protein LSM PF01423.22 EST49471.1 - 1.1e-13 50.6 0.7 1.3e-13 50.4 0.7 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EST49471.1 - 0.0025 17.9 0.0 0.003 17.7 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 EST49471.1 - 0.0054 16.8 0.1 0.0082 16.2 0.1 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain Sigma54_AID PF00309.20 EST49472.1 - 0.31 10.9 3.7 17 5.3 0.0 3.2 2 0 0 2 2 2 0 Sigma-54 factor, Activator interacting domain (AID) cNMP_binding PF00027.29 EST49473.1 - 7.5e-34 115.7 0.0 4.3e-16 58.8 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Syndecan PF01034.20 EST49474.1 - 0.033 14.1 0.4 0.055 13.4 0.4 1.4 1 0 0 1 1 1 0 Syndecan domain EVI2A PF05399.11 EST49474.1 - 0.18 11.4 0.1 0.22 11.1 0.1 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) DUF3149 PF11346.8 EST49474.1 - 1.1 8.9 6.1 2.2 7.9 6.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Mog1 PF04603.12 EST49476.1 - 6.4e-13 49.3 0.1 3.8e-12 46.7 0.1 1.9 1 1 0 1 1 1 1 Ran-interacting Mog1 protein LeuA_dimer PF08502.10 EST49477.1 - 0.058 13.3 0.1 0.1 12.5 0.0 1.5 2 0 0 2 2 2 0 LeuA allosteric (dimerisation) domain bZIP_Maf PF03131.17 EST49477.1 - 0.94 10.0 13.0 0.1 13.1 3.8 2.7 1 1 0 2 2 2 0 bZIP Maf transcription factor CENP-F_leu_zip PF10473.9 EST49477.1 - 2.9 7.9 18.8 0.079 13.0 8.4 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cep57_CLD_2 PF14197.6 EST49477.1 - 8 6.6 11.5 0.31 11.2 2.6 2.7 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 Seryl_tRNA_N PF02403.22 EST49478.1 - 0.013 15.7 1.7 0.039 14.2 0.5 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF5089 PF17002.5 EST49478.1 - 0.015 15.1 0.2 0.015 15.1 0.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF5089) Corona_S2 PF01601.16 EST49478.1 - 0.03 12.9 3.5 0.042 12.3 3.5 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein PsiF_repeat PF07769.14 EST49478.1 - 0.077 12.9 0.0 0.34 10.8 0.1 2.0 2 0 0 2 2 2 0 psiF repeat Phage_Mu_Gam PF07352.12 EST49478.1 - 0.17 11.8 2.9 0.36 10.7 2.9 1.5 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein SAPIS-gp6 PF16722.5 EST49478.1 - 0.34 11.4 3.5 0.28 11.6 1.4 1.8 1 1 0 1 1 1 0 Pathogenicity island protein gp6 in Staphylococcus ATP-synt_G PF04718.15 EST49478.1 - 0.6 11.0 5.0 2.2 9.2 5.0 2.0 1 1 0 1 1 1 0 Mitochondrial ATP synthase g subunit KNOX2 PF03791.13 EST49478.1 - 0.72 9.4 3.3 1 8.9 0.2 2.5 2 1 1 3 3 3 0 KNOX2 domain TTL PF03133.15 EST49479.1 - 3.6e-55 187.2 3.6 5.5e-55 186.6 3.6 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EST49479.1 - 5.6e-10 38.9 0.3 0.00082 18.7 0.0 2.4 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EST49479.1 - 2.5e-07 30.2 0.0 0.0028 17.0 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp GARS_A PF01071.19 EST49479.1 - 0.00037 20.3 0.0 0.0012 18.6 0.0 1.8 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 EST49479.1 - 0.0038 16.8 0.1 0.085 12.4 0.0 2.3 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 EST49479.1 - 0.011 15.8 0.0 0.091 12.8 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain HABP4_PAI-RBP1 PF04774.15 EST49479.1 - 0.038 14.8 0.3 0.29 12.0 0.1 2.1 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family LRR_6 PF13516.6 EST49480.1 - 0.0003 20.6 1.0 0.58 10.4 0.0 3.3 3 0 0 3 3 3 2 Leucine Rich repeat MgsA_C PF12002.8 EST49481.1 - 3.3e-30 105.2 0.0 4.9e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.29 EST49481.1 - 5.8e-11 42.9 0.2 1.3e-10 41.8 0.2 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EST49481.1 - 5e-07 30.3 0.4 0.0021 18.5 0.0 3.0 1 1 1 3 3 3 2 AAA ATPase domain RuvB_N PF05496.12 EST49481.1 - 8.8e-06 25.6 0.0 4.4e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EST49481.1 - 3.5e-05 24.1 0.7 0.045 14.0 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_14 PF13173.6 EST49481.1 - 8.2e-05 22.7 0.0 0.00017 21.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EST49481.1 - 0.00014 21.6 0.2 0.048 13.4 0.2 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 EST49481.1 - 0.00016 21.7 0.1 0.0075 16.3 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EST49481.1 - 0.00018 22.1 0.1 0.00086 19.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 EST49481.1 - 0.00023 21.4 0.1 0.0011 19.3 0.1 2.2 1 1 0 1 1 1 1 AAA C-terminal domain Mg_chelatase PF01078.21 EST49481.1 - 0.0007 19.0 0.1 0.052 12.9 0.0 3.0 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 EST49481.1 - 0.0029 18.0 1.1 1.2 9.5 0.0 2.7 2 1 1 3 3 3 1 AAA domain DUF815 PF05673.13 EST49481.1 - 0.012 14.8 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 EST49481.1 - 0.028 14.6 0.0 0.052 13.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain CPT PF07931.12 EST49481.1 - 0.029 14.2 0.0 0.064 13.1 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DNA_pol3_delta2 PF13177.6 EST49481.1 - 0.031 14.1 1.2 3.5 7.4 0.5 2.7 3 0 0 3 3 3 0 DNA polymerase III, delta subunit NACHT PF05729.12 EST49481.1 - 0.053 13.4 0.1 0.18 11.7 0.0 1.8 1 1 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 EST49481.1 - 0.055 13.2 0.2 0.38 10.4 0.0 2.3 2 1 0 2 2 2 0 AAA domain PRK PF00485.18 EST49481.1 - 0.058 13.1 0.2 1.7 8.3 0.1 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family TsaE PF02367.17 EST49481.1 - 0.07 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 EST49481.1 - 0.081 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 EST49481.1 - 0.11 11.6 0.1 0.24 10.6 0.1 1.6 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 EST49481.1 - 0.11 12.1 0.1 0.24 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain tRNA-synt_1 PF00133.22 EST49483.1 - 3.9e-40 137.7 0.0 1.9e-28 99.1 0.0 2.7 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EST49483.1 - 2.7e-23 82.4 0.3 1.1e-10 40.9 0.0 3.3 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EST49483.1 - 6.1e-08 32.8 0.1 1.5e-07 31.5 0.1 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EST49483.1 - 3.8e-07 29.7 0.0 7.9e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain CEP63 PF17045.5 EST49483.1 - 0.039 13.8 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa tRNA-synt_1_2 PF13603.6 EST49483.1 - 0.056 13.0 0.1 1.3 8.5 0.0 2.6 2 0 0 2 2 2 0 Leucyl-tRNA synthetase, Domain 2 DUF3417 PF11897.8 EST49483.1 - 0.093 13.2 0.1 2.3 8.7 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3417) DUF4292 PF14125.6 EST49483.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4292) Robl_LC7 PF03259.17 EST49485.1 - 7e-10 38.6 0.0 8.3e-10 38.3 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain SRTM1 PF15872.5 EST49486.1 - 0.046 13.9 0.4 0.089 12.9 0.4 1.5 1 0 0 1 1 1 0 Serine-rich and transmembrane domain-containing protein 1 TMEM154 PF15102.6 EST49486.1 - 0.2 11.6 1.0 1.6 8.6 1.1 2.0 2 0 0 2 2 2 0 TMEM154 protein family Aa_trans PF01490.18 EST49488.1 - 1.2e-13 50.6 47.7 7.1e-13 48.0 44.4 2.7 2 1 0 2 2 2 1 Transmembrane amino acid transporter protein PHO4 PF01384.20 EST49490.1 - 0.05 12.6 0.2 0.05 12.7 0.2 1.1 1 0 0 1 1 1 0 Phosphate transporter family Fes1 PF08609.10 EST49493.1 - 9.1e-06 26.5 2.2 8.9e-05 23.3 0.3 2.5 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 TSCPD PF12637.7 EST49493.1 - 0.01 16.1 0.1 0.026 14.8 0.1 1.7 1 0 0 1 1 1 0 TSCPD domain EF-hand_7 PF13499.6 EST49494.1 - 3.1e-09 37.1 0.5 4.1e-09 36.8 0.5 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EST49494.1 - 2.1e-08 33.9 0.3 3.3e-08 33.3 0.3 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EST49494.1 - 5.3e-08 31.9 0.9 0.0012 18.3 0.4 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EST49494.1 - 1.1e-06 28.1 0.1 0.0082 16.0 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_10 PF14788.6 EST49494.1 - 0.003 17.4 0.2 0.015 15.2 0.1 2.1 1 1 1 2 2 2 1 EF hand EF-hand_4 PF12763.7 EST49494.1 - 0.0044 16.9 0.2 0.0055 16.6 0.2 1.3 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand TB2_DP1_HVA22 PF03134.19 EST49495.1 - 5.6e-18 64.6 1.5 7.5e-18 64.2 1.5 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family PAXX PF15384.6 EST49496.1 - 0.1 12.3 0.8 0.15 11.8 0.2 1.5 2 0 0 2 2 2 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 Methyltransf_8 PF05148.15 EST49500.1 - 1.1e-46 159.5 0.0 1.3e-46 159.2 0.0 1.1 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 EST49500.1 - 0.0012 19.5 0.0 0.0051 17.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EST49500.1 - 0.0026 18.5 0.1 0.038 14.7 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EST49500.1 - 0.0049 16.7 0.0 0.42 10.4 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 EST49500.1 - 0.18 11.1 0.0 0.38 10.0 0.0 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Vhr1 PF04001.13 EST49501.1 - 0.049 13.9 0.1 0.057 13.7 0.1 1.1 1 0 0 1 1 1 0 Transcription factor Vhr1 PP2C PF00481.21 EST49502.1 - 2e-23 83.4 0.0 3.5e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EST49502.1 - 2.6e-05 24.0 0.2 0.00034 20.3 0.0 2.8 2 1 0 2 2 2 1 Protein phosphatase 2C INCENP_N PF12178.8 EST49502.1 - 0.12 12.4 0.4 0.26 11.3 0.4 1.5 1 0 0 1 1 1 0 Chromosome passenger complex (CPC) protein INCENP N terminal ApoLp-III PF07464.11 EST49502.1 - 0.37 10.9 5.3 2.5 8.2 0.4 2.2 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) CRT10 PF08728.10 EST49504.1 - 0.021 13.0 0.1 0.025 12.8 0.1 1.0 1 0 0 1 1 1 0 CRT10 DNA_RNApol_7kD PF03604.13 EST49505.1 - 8.7e-06 25.3 0.8 8.7e-06 25.3 0.8 1.8 2 1 0 2 2 2 1 DNA directed RNA polymerase, 7 kDa subunit DUF2318 PF10080.9 EST49505.1 - 0.0078 16.3 0.3 0.0078 16.3 0.3 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2318) PI3K_rbd PF00794.18 EST49505.1 - 0.015 15.5 0.1 0.015 15.5 0.1 1.0 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain Myb_DNA-bind_6 PF13921.6 EST49506.1 - 5.4e-15 55.4 1.7 4.8e-09 36.3 0.3 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EST49506.1 - 1.4e-10 41.1 0.8 0.00011 22.4 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EST49507.1 - 9.1e-12 45.0 5.7 8.5e-07 29.1 0.8 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EST49507.1 - 2.2e-10 40.6 3.5 3.2e-08 33.7 1.3 2.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EST49507.1 - 0.0053 17.1 1.1 0.0053 17.1 1.1 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Rap1_C PF11626.8 EST49507.1 - 0.014 15.5 0.2 0.024 14.7 0.2 1.5 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 EST49507.1 - 0.1 12.8 3.4 4.9 7.4 0.4 2.3 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 HARE-HTH PF05066.13 EST49507.1 - 0.12 12.7 0.3 1 9.8 0.1 2.2 2 1 0 2 2 2 0 HB1, ASXL, restriction endonuclease HTH domain DUF4107 PF13389.6 EST49508.1 - 0.14 12.3 0.1 0.17 12.0 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4107) RTP1_C1 PF10363.9 EST49510.1 - 0.01 16.0 0.6 0.051 13.7 0.1 2.4 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 PurS PF02700.14 EST49513.1 - 0.092 12.9 0.1 0.26 11.5 0.1 1.7 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine (FGAM) synthase UPF0154 PF03672.13 EST49513.1 - 0.7 10.0 4.4 0.57 10.2 0.5 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) tRNA-synt_2d PF01409.20 EST49516.1 - 3.6e-86 288.6 0.0 5.9e-86 287.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA_synthFbeta PF17759.1 EST49516.1 - 1.3e-05 24.8 0.0 0.00028 20.4 0.0 2.2 2 0 0 2 2 2 1 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2b PF00587.25 EST49516.1 - 0.00027 21.0 0.0 0.00047 20.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 EST49516.1 - 0.0023 17.1 0.2 0.011 14.9 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) PheRS_DBD1 PF18552.1 EST49516.1 - 0.0084 15.8 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 PheRS DNA binding domain 1 DUF4208 PF13907.6 EST49516.1 - 0.081 13.4 0.4 51 4.4 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4208) DMAP_binding PF06464.11 EST49516.1 - 0.2 12.5 1.3 0.87 10.4 0.7 2.5 3 1 0 3 3 3 0 DMAP1-binding Domain Cnn_1N PF07989.11 EST49517.1 - 0.0068 16.5 0.9 0.015 15.4 0.9 1.6 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 TSC22 PF01166.18 EST49517.1 - 0.011 16.1 0.8 0.12 12.7 0.1 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family bZIP_1 PF00170.21 EST49517.1 - 0.061 13.4 1.6 9.3 6.4 0.1 2.4 2 0 0 2 2 2 0 bZIP transcription factor HALZ PF02183.18 EST49517.1 - 0.08 13.2 2.6 1.1 9.5 0.1 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper Shugoshin_N PF07558.11 EST49517.1 - 0.091 12.6 0.0 0.33 10.8 0.0 2.0 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Endonuc_subdom PF09062.10 EST49517.1 - 0.12 13.2 0.1 0.25 12.2 0.1 1.4 1 0 0 1 1 1 0 PI-PfuI Endonuclease subdomain ZapB PF06005.12 EST49517.1 - 0.27 11.7 7.9 2.4 8.7 4.1 2.6 2 1 0 2 2 2 0 Cell division protein ZapB YabA PF06156.13 EST49517.1 - 0.47 11.1 2.8 2 9.1 0.3 2.4 1 1 1 2 2 2 0 Initiation control protein YabA DUF2960 PF11173.8 EST49520.1 - 0.8 10.2 6.0 3.3 8.2 1.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2960) CHASE PF03924.13 EST49521.1 - 0.18 11.7 0.0 0.19 11.6 0.0 1.0 1 0 0 1 1 1 0 CHASE domain Ago_N_1 PF18351.1 EST49523.1 - 0.072 13.5 0.0 0.081 13.4 0.0 1.1 1 0 0 1 1 1 0 Fungal Argonaute N-terminal domain Cor1 PF04803.12 EST49524.1 - 0.0038 17.4 0.2 0.024 14.9 0.0 2.0 2 0 0 2 2 2 1 Cor1/Xlr/Xmr conserved region Thioredoxin_13 PF18401.1 EST49524.1 - 0.1 12.5 0.0 0.29 11.1 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like domain Enkurin PF13864.6 EST49525.1 - 0.002 18.5 1.3 0.0026 18.2 1.3 1.2 1 0 0 1 1 1 1 Calmodulin-binding Glyco_hydro_2_N PF02837.18 EST49526.1 - 0.017 15.0 0.4 0.017 15.0 0.4 1.7 2 0 0 2 2 2 0 Glycosyl hydrolases family 2, sugar binding domain Tnp_P_element PF12017.8 EST49527.1 - 0.018 14.4 0.1 0.9 8.9 0.0 2.4 1 1 1 2 2 2 0 Transposase protein Saf_2TM PF18303.1 EST49527.1 - 0.073 12.7 0.8 0.21 11.2 0.3 2.0 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain Saf_2TM PF18303.1 EST49528.1 - 0.1 12.2 1.6 0.22 11.1 0.8 2.0 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain OSTbeta PF15048.6 EST49528.1 - 0.34 11.0 1.2 0.89 9.7 1.2 1.7 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Collectrin PF16959.5 EST49528.1 - 3.8 7.3 8.2 15 5.4 0.1 2.9 3 0 0 3 3 3 0 Renal amino acid transporter Thioredoxin PF00085.20 EST49530.1 - 9.4e-25 86.6 0.0 1.8e-23 82.4 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 EST49530.1 - 0.0023 18.4 0.1 0.018 15.5 0.1 2.3 2 1 0 2 2 2 1 Thioredoxin-like domain Calsequestrin PF01216.17 EST49530.1 - 0.0063 15.6 0.2 0.043 12.9 0.0 1.9 1 1 1 2 2 2 1 Calsequestrin Thioredoxin_8 PF13905.6 EST49530.1 - 0.05 13.9 0.0 0.54 10.6 0.0 2.6 2 1 0 2 2 2 0 Thioredoxin-like Ribosomal_L1 PF00687.21 EST49532.1 - 5.3e-29 101.4 2.6 6.3e-29 101.2 2.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family LIG3_BRCT PF16759.5 EST49532.1 - 0.011 16.0 0.0 0.023 15.0 0.0 1.6 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain XLF PF09302.11 EST49532.1 - 0.031 14.4 0.1 0.046 13.9 0.1 1.3 1 0 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Get5_C PF18514.1 EST49532.1 - 0.084 12.6 0.1 0.22 11.2 0.1 1.8 2 0 0 2 2 2 0 Get5 C-terminal domain HTH_11 PF08279.12 EST49534.1 - 0.095 12.7 0.1 0.29 11.1 0.1 1.8 1 0 0 1 1 1 0 HTH domain DUF3597 PF12200.8 EST49534.1 - 0.78 10.3 6.1 2.8 8.5 0.6 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3597) His_Phos_2 PF00328.22 EST49536.1 - 4.8e-10 39.3 1.0 5.1e-07 29.4 0.7 3.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) H-kinase_dim PF02895.14 EST49537.1 - 0.00026 21.3 0.2 0.00027 21.3 0.2 1.2 1 1 0 1 1 1 1 Signal transducing histidine kinase, homodimeric domain Nse4_C PF08743.10 EST49537.1 - 0.027 14.7 0.2 0.053 13.8 0.2 1.5 1 1 0 1 1 1 0 Nse4 C-terminal DUF4927 PF16279.5 EST49537.1 - 0.066 14.2 0.1 0.084 13.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4927) DUF5494 PF17598.2 EST49538.1 - 0.18 11.9 1.2 0.65 10.2 0.3 2.2 2 1 0 2 2 2 0 Family of unknown function (DUF5494) DUF3747 PF12565.8 EST49541.1 - 0.013 14.9 0.3 0.056 12.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3747) CcmD PF04995.14 EST49541.1 - 0.032 14.3 0.3 0.058 13.5 0.3 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) NS3_envE PF02723.14 EST49541.1 - 0.51 10.5 8.3 0.15 12.1 4.7 2.0 2 0 0 2 2 2 0 Non-structural protein NS3/Small envelope protein E Peptidase_M57 PF12388.8 EST49542.1 - 0.15 11.6 1.0 0.33 10.5 1.0 1.5 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Ribosomal_L29 PF00831.23 EST49542.1 - 0.2 11.7 4.3 1.6 8.8 0.3 3.5 2 1 0 2 2 2 0 Ribosomal L29 protein LEDGF PF11467.8 EST49542.1 - 2 8.1 9.4 0.48 10.1 0.9 2.6 3 0 0 3 3 3 0 Lens epithelium-derived growth factor (LEDGF) CC2-LZ PF16516.5 EST49542.1 - 7.5 7.0 29.3 2.6 8.5 9.8 3.4 1 1 2 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Yuri_gagarin PF15934.5 EST49543.1 - 0.027 14.3 0.6 0.033 14.0 0.6 1.3 1 1 0 1 1 1 0 Yuri gagarin Csm1_N PF18504.1 EST49543.1 - 0.077 13.3 0.6 0.1 13.0 0.6 1.3 1 0 0 1 1 1 0 Csm1 N-terminal domain HTH_13 PF11972.8 EST49543.1 - 0.093 12.8 0.1 0.12 12.4 0.1 1.2 1 0 0 1 1 1 0 HTH DNA binding domain DASH_Dam1 PF08653.10 EST49543.1 - 0.16 11.8 0.8 0.3 10.9 0.2 1.8 2 1 0 2 2 2 0 DASH complex subunit Dam1 Fer4 PF00037.27 EST49544.1 - 3.6e-10 39.2 27.3 1.2e-05 24.9 9.6 2.3 2 1 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EST49544.1 - 4.7e-08 33.5 18.8 8.1e-08 32.7 18.9 1.4 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 EST49544.1 - 1.6e-07 31.3 18.5 1.8e-07 31.1 18.5 1.1 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 EST49544.1 - 2.2e-06 27.4 21.9 9.1e-05 22.3 4.0 2.7 2 1 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 EST49544.1 - 2.2e-06 27.7 18.8 3.3e-06 27.2 18.8 1.3 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 EST49544.1 - 2.3e-06 27.6 19.1 4e-05 23.6 19.7 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 EST49544.1 - 2.1e-05 25.4 19.5 0.0043 18.0 3.6 2.1 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_6 PF12837.7 EST49544.1 - 2.2e-05 24.3 26.6 0.031 14.4 12.3 2.6 1 1 1 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 EST49544.1 - 0.00023 21.4 21.4 0.05 14.1 7.3 2.9 1 1 1 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 EST49544.1 - 0.00049 20.5 17.3 0.0095 16.4 2.9 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 EST49544.1 - 0.0024 18.7 20.0 0.14 13.1 4.2 2.8 3 1 0 3 3 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 EST49544.1 - 0.0029 18.1 17.5 0.15 12.6 6.3 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.6 EST49544.1 - 0.0046 17.7 9.1 0.0046 17.7 9.1 2.8 1 1 2 3 3 3 1 4Fe-4S single cluster domain Fer4_13 PF13370.6 EST49544.1 - 0.024 15.2 22.2 0.11 13.1 8.9 2.5 1 1 1 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 EST49544.1 - 0.13 12.5 16.7 0.16 12.2 6.4 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 EST49544.1 - 0.54 11.1 18.1 1.8 9.5 3.7 2.1 1 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4 PF00037.27 EST49545.1 - 3.6e-10 39.2 27.3 1.2e-05 24.9 9.6 2.3 2 1 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EST49545.1 - 4.7e-08 33.5 18.8 8.1e-08 32.7 18.9 1.4 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 EST49545.1 - 1.6e-07 31.3 18.5 1.8e-07 31.1 18.5 1.1 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 EST49545.1 - 2.2e-06 27.4 21.9 9.1e-05 22.3 4.0 2.7 2 1 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 EST49545.1 - 2.2e-06 27.7 18.8 3.3e-06 27.2 18.8 1.3 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 EST49545.1 - 2.3e-06 27.6 19.1 4e-05 23.6 19.7 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 EST49545.1 - 2.1e-05 25.4 19.5 0.0043 18.0 3.6 2.1 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_6 PF12837.7 EST49545.1 - 2.2e-05 24.3 26.6 0.031 14.4 12.3 2.6 1 1 1 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 EST49545.1 - 0.00023 21.4 21.4 0.05 14.1 7.3 2.9 1 1 1 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 EST49545.1 - 0.00049 20.5 17.3 0.0095 16.4 2.9 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_3 PF12798.7 EST49545.1 - 0.0024 18.7 20.0 0.14 13.1 4.2 2.8 3 1 0 3 3 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 EST49545.1 - 0.0029 18.1 17.5 0.15 12.6 6.3 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.6 EST49545.1 - 0.0046 17.7 9.1 0.0046 17.7 9.1 2.8 1 1 2 3 3 3 1 4Fe-4S single cluster domain Fer4_13 PF13370.6 EST49545.1 - 0.024 15.2 22.2 0.11 13.1 8.9 2.5 1 1 1 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 EST49545.1 - 0.13 12.5 16.7 0.16 12.2 6.4 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 EST49545.1 - 0.54 11.1 18.1 1.8 9.5 3.7 2.1 1 1 1 3 3 3 0 4Fe-4S dicluster domain Aa_trans PF01490.18 EST49546.1 - 7.8e-29 100.6 47.6 1.2e-28 99.9 47.6 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AAA_6 PF12774.7 EST49547.1 - 1.6e-128 428.3 0.0 9.4e-128 425.8 0.0 2.6 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EST49547.1 - 6.1e-116 387.8 7.7 6.1e-116 387.8 7.7 4.9 7 0 0 7 7 5 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 EST49547.1 - 4.7e-100 335.9 20.4 4.7e-100 335.9 20.4 3.4 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 AAA_8 PF12780.7 EST49547.1 - 4.6e-86 288.3 2.7 1.7e-85 286.5 0.0 3.1 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 EST49547.1 - 4.3e-78 261.4 4.0 4.3e-78 261.4 4.0 6.2 5 1 1 6 6 5 2 ATP-binding dynein motor region Dynein_C PF18199.1 EST49547.1 - 7.9e-75 251.9 10.4 5.5e-74 249.2 0.2 4.4 4 0 0 4 4 4 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 EST49547.1 - 9.4e-66 220.8 0.1 5e-59 198.9 0.0 4.0 4 0 0 4 4 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EST49547.1 - 5.7e-46 156.3 0.2 9.7e-45 152.3 0.2 2.9 1 1 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EST49547.1 - 4.7e-39 133.1 0.2 1.2e-35 122.2 0.2 4.2 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 EST49547.1 - 2.4e-32 112.3 18.1 2.4e-32 112.3 18.1 3.2 4 0 0 4 4 4 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 EST49547.1 - 1.2e-25 90.1 2.3 4.1e-07 30.1 0.0 6.8 7 1 0 7 7 6 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 EST49547.1 - 1.1e-22 80.5 0.0 1.4e-21 76.9 0.0 3.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 EST49547.1 - 4.8e-16 58.8 0.1 4.1e-15 55.8 0.1 2.8 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 EST49547.1 - 1.6e-10 41.5 3.1 0.0093 16.4 0.0 6.4 6 0 0 6 6 5 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EST49547.1 - 8e-09 35.9 1.1 0.027 14.7 0.0 5.9 6 0 0 6 6 6 2 AAA domain AAA_16 PF13191.6 EST49547.1 - 2e-05 25.1 5.5 0.043 14.2 0.0 6.1 5 0 0 5 5 5 1 AAA ATPase domain IstB_IS21 PF01695.17 EST49547.1 - 6.5e-05 22.7 0.2 0.079 12.7 0.0 4.0 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_33 PF13671.6 EST49547.1 - 0.00017 21.8 0.7 3.1 8.0 0.0 5.0 4 0 0 4 4 4 1 AAA domain PhoH PF02562.16 EST49547.1 - 0.017 14.6 1.7 1.4 8.4 0.0 3.7 3 0 0 3 3 3 0 PhoH-like protein ABC_tran PF00005.27 EST49547.1 - 0.048 14.2 2.0 4.8 7.7 0.0 4.2 3 0 0 3 3 2 0 ABC transporter Sigma54_activat PF00158.26 EST49547.1 - 0.048 13.4 0.0 11 5.7 0.0 3.0 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 EST49547.1 - 0.068 12.6 0.1 3.4 7.0 0.0 2.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Roc PF08477.13 EST49547.1 - 0.072 13.3 0.8 3.6 7.8 0.0 3.5 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase CBP_BcsN PF17038.5 EST49547.1 - 0.12 11.8 0.1 0.36 10.2 0.1 1.8 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsN VirE3 PF06661.11 EST49547.1 - 0.18 11.0 1.9 0.17 11.1 0.2 1.7 2 0 0 2 2 2 0 VirE3 Peptidase_M3_N PF08439.10 EST49547.1 - 0.33 11.2 2.1 1.2 9.4 0.1 3.0 2 0 0 2 2 2 0 Oligopeptidase F Snapin_Pallidin PF14712.6 EST49548.1 - 1.8e-05 25.1 7.8 2.1e-05 24.8 7.8 1.0 1 0 0 1 1 1 1 Snapin/Pallidin phiKZ_IP PF12699.7 EST49548.1 - 0.016 14.3 0.3 0.027 13.6 0.1 1.3 1 1 0 1 1 1 0 phiKZ-like phage internal head proteins Yopt PF09467.10 EST49550.1 - 0.16 12.1 0.0 0.22 11.6 0.0 1.3 1 1 0 1 1 1 0 Hypothetical protein Yopt DUF3681 PF12442.8 EST49552.1 - 0.66 10.5 3.6 2 9.0 0.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3681) Aa_trans PF01490.18 EST49553.1 - 4.5e-35 121.2 45.3 5.4e-35 120.9 45.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein HupF_HypC PF01455.18 EST49557.1 - 0.22 11.7 0.9 0.43 10.8 0.3 1.7 2 0 0 2 2 2 0 HupF/HypC family Beta_elim_lyase PF01212.21 EST49561.1 - 1.3e-54 185.5 0.0 1.7e-54 185.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 EST49561.1 - 0.064 11.9 0.0 0.098 11.3 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Aminotran_1_2 PF00155.21 EST49561.1 - 0.16 11.1 0.0 1.7 7.7 0.0 2.4 3 0 0 3 3 3 0 Aminotransferase class I and II Thioredoxin_9 PF14595.6 EST49562.1 - 4.9e-12 45.8 0.0 5.9e-12 45.5 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin PF00085.20 EST49562.1 - 2.3e-10 40.4 0.1 2.6e-10 40.2 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EST49562.1 - 3.2e-05 24.2 0.0 0.054 13.8 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EST49562.1 - 0.00042 20.7 0.0 0.00067 20.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EST49562.1 - 0.0031 17.7 0.5 0.0073 16.5 0.5 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.6 EST49562.1 - 0.0035 17.4 0.1 0.0049 16.9 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin domain DUF953 PF06110.11 EST49562.1 - 0.0049 16.5 0.1 0.0067 16.0 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) HyaE PF07449.11 EST49562.1 - 0.011 15.7 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.24 EST49562.1 - 0.049 13.9 0.1 0.11 12.8 0.1 1.6 1 1 1 2 2 2 0 Glutaredoxin TraF PF13728.6 EST49562.1 - 0.052 13.4 0.0 0.063 13.1 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_5 PF13743.6 EST49562.1 - 0.067 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin QSOX_Trx1 PF18108.1 EST49562.1 - 0.13 12.4 0.0 0.19 12.0 0.0 1.2 1 0 0 1 1 1 0 QSOX Trx-like domain DUF2617 PF10936.8 EST49564.1 - 0.079 13.0 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF2617 LSM14 PF12701.7 EST49564.1 - 0.12 12.5 1.4 1.7 8.8 0.2 2.3 2 0 0 2 2 2 0 Scd6-like Sm domain Amidase_2 PF01510.25 EST49564.1 - 0.15 12.5 0.9 4.9 7.6 0.5 2.4 1 1 1 2 2 2 0 N-acetylmuramoyl-L-alanine amidase Fer4_24 PF18109.1 EST49564.1 - 0.63 10.4 5.0 14 6.0 0.2 2.8 2 0 0 2 2 2 0 Ferredoxin I 4Fe-4S cluster domain Sigma54_DBD PF04552.13 EST49564.1 - 0.67 9.6 6.6 0.17 11.6 3.2 1.8 2 1 0 2 2 2 0 Sigma-54, DNA binding domain HALZ PF02183.18 EST49564.1 - 4.7 7.5 8.7 39 4.6 0.3 3.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper bZIP_2 PF07716.15 EST49564.1 - 9.2 6.4 11.5 1.3 9.2 1.7 2.9 3 0 0 3 3 3 0 Basic region leucine zipper Kelch_4 PF13418.6 EST49565.1 - 7.3e-29 99.5 2.5 5.3e-07 29.5 0.0 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 EST49565.1 - 2.9e-28 97.5 7.4 3.4e-06 27.2 0.1 6.8 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.6 EST49565.1 - 3.3e-24 84.4 5.5 2.3e-08 33.8 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 EST49565.1 - 1.3e-20 72.7 0.1 1.7e-05 24.3 0.0 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 EST49565.1 - 2.6e-18 65.6 4.1 0.0027 17.9 0.0 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 EST49565.1 - 3.7e-15 55.2 6.1 7.9e-05 22.5 0.0 6.0 6 0 0 6 6 6 3 Kelch motif DUF3213 PF11491.8 EST49565.1 - 0.82 9.9 3.3 25 5.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3213) DUF1664 PF07889.12 EST49565.1 - 2.8 8.0 9.9 0.079 13.0 1.9 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4366 PF14283.6 EST49566.1 - 0.00019 21.5 0.2 0.00024 21.2 0.2 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4366) VSP PF03302.13 EST49566.1 - 0.00025 20.1 12.7 0.00046 19.2 12.7 1.5 1 1 0 1 1 1 1 Giardia variant-specific surface protein Podoplanin PF05808.11 EST49566.1 - 0.056 13.5 0.1 0.11 12.5 0.0 1.5 2 0 0 2 2 2 0 Podoplanin Gram_pos_anchor PF00746.21 EST49566.1 - 0.12 12.4 0.9 0.19 11.7 0.9 1.3 1 0 0 1 1 1 0 LPXTG cell wall anchor motif PARM PF17061.5 EST49566.1 - 8.6 6.4 7.2 14 5.7 6.7 1.5 1 1 0 1 1 1 0 PARM Orai-1 PF07856.12 EST49567.1 - 0.67 9.6 8.7 0.75 9.4 6.9 1.9 1 1 1 2 2 2 0 Mediator of CRAC channel activity LBP_BPI_CETP PF01273.25 EST49569.1 - 0.038 13.6 0.8 0.075 12.6 0.8 1.5 1 0 0 1 1 1 0 LBP / BPI / CETP family, N-terminal domain Furin-like_2 PF15913.5 EST49570.1 - 1.5e-10 41.2 167.7 0.00027 21.0 13.8 10.2 1 1 10 11 11 11 6 Furin-like repeat, cysteine-rich VSP PF03302.13 EST49570.1 - 5.1e-08 32.2 176.2 0.037 12.9 35.6 7.9 1 1 6 7 7 7 5 Giardia variant-specific surface protein DUF4366 PF14283.6 EST49570.1 - 3.5 7.6 5.2 0.79 9.8 0.6 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) Tctex-1 PF03645.13 EST49571.1 - 6.9e-30 103.3 0.4 7.8e-30 103.2 0.4 1.0 1 0 0 1 1 1 1 Tctex-1 family QueF PF14489.6 EST49571.1 - 0.045 13.9 0.1 0.15 12.2 0.0 1.7 1 1 1 2 2 2 0 QueF-like protein Pox_VLTF3 PF04947.14 EST49571.1 - 0.063 13.0 0.1 0.077 12.7 0.1 1.1 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like DLP_helical PF18709.1 EST49571.1 - 0.087 12.0 0.2 0.095 11.9 0.2 1.1 1 0 0 1 1 1 0 Dynamin-like helical domain Plasmodium_HRP PF05403.11 EST49572.1 - 0.17 11.6 2.5 0.34 10.7 2.5 1.4 1 0 0 1 1 1 0 Plasmodium histidine-rich protein (HRPII/III) Metallophos PF00149.28 EST49573.1 - 2.5e-23 83.7 0.9 3.8e-23 83.0 0.9 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4366 PF14283.6 EST49577.1 - 0.00046 20.3 0.0 0.0012 19.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) VSP PF03302.13 EST49577.1 - 0.00076 18.4 58.4 0.0009 18.2 12.2 2.4 1 1 1 2 2 2 1 Giardia variant-specific surface protein Podoplanin PF05808.11 EST49577.1 - 0.1 12.7 0.2 0.34 11.0 0.0 1.8 2 0 0 2 2 2 0 Podoplanin Gram_pos_anchor PF00746.21 EST49577.1 - 0.3 11.1 0.9 0.48 10.4 0.9 1.3 1 0 0 1 1 1 0 LPXTG cell wall anchor motif MSG PF02349.15 EST49578.1 - 0.17 12.1 2.8 0.24 11.6 2.8 1.3 1 0 0 1 1 1 0 Major surface glycoprotein LBP_BPI_CETP PF01273.25 EST49579.1 - 0.0032 17.1 1.6 0.0087 15.7 1.6 1.8 1 1 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain Glyco_hydro_35 PF01301.19 EST49580.1 - 5.8e-35 121.4 0.0 9.8e-35 120.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Cellulase PF00150.18 EST49580.1 - 0.00039 20.0 0.5 0.00068 19.2 0.2 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DUF4874 PF16173.5 EST49580.1 - 0.087 12.5 0.1 0.26 11.0 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4874) DUF4434 PF14488.6 EST49580.1 - 0.093 12.7 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) PK PF00224.21 EST49582.1 - 2.2e-24 86.0 0.0 2.4e-24 85.9 0.0 1.0 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain Podoplanin PF05808.11 EST49583.1 - 0.082 13.0 3.9 0.21 11.7 4.1 1.7 1 1 0 1 1 1 0 Podoplanin DUF4366 PF14283.6 EST49583.1 - 1.3 9.1 5.7 4.3 7.4 5.7 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Myb_DNA-bind_7 PF15963.5 EST49584.1 - 0.0047 16.8 1.0 0.0066 16.3 1.0 1.2 1 0 0 1 1 1 1 Myb DNA-binding like Fox-1_C PF12414.8 EST49585.1 - 0.051 14.0 0.2 0.053 13.9 0.2 1.1 1 0 0 1 1 1 0 Calcitonin gene-related peptide regulator C terminal Pox_A11 PF05061.13 EST49585.1 - 0.21 10.9 0.0 0.23 10.7 0.0 1.0 1 0 0 1 1 1 0 Poxvirus A11 Protein zf-CHCC PF10276.9 EST49586.1 - 0.37 10.9 4.3 11 6.1 0.1 3.4 4 1 1 5 5 5 0 Zinc-finger domain zf-ribbon_3 PF13248.6 EST49586.1 - 2 7.9 10.0 0.35 10.3 3.8 2.6 2 1 0 2 2 2 0 zinc-ribbon domain UPF0242 PF06785.11 EST49587.1 - 0.11 12.5 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Cupin_2 PF07883.11 EST49587.1 - 0.14 11.9 0.4 0.22 11.3 0.4 1.3 1 0 0 1 1 1 0 Cupin domain XTBD PF11952.8 EST49588.1 - 0.018 14.8 0.6 0.032 14.0 0.6 1.4 1 0 0 1 1 1 0 XRN-Two Binding Domain, XTBD Flu_M2 PF00599.17 EST49588.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Influenza Matrix protein (M2) Cupin_2 PF07883.11 EST49588.1 - 0.14 11.9 0.4 0.21 11.4 0.4 1.2 1 0 0 1 1 1 0 Cupin domain EGF_2 PF07974.13 EST49589.1 - 0.026 14.9 11.8 0.026 14.9 11.8 3.6 3 0 0 3 3 3 0 EGF-like domain EGF_2 PF07974.13 EST49592.1 - 0.03 14.7 11.8 0.03 14.7 11.8 6.3 5 0 0 5 5 5 0 EGF-like domain Yip1 PF04893.17 EST49594.1 - 0.00026 20.8 24.7 0.00026 20.8 24.7 1.9 1 1 1 2 2 2 1 Yip1 domain Interferon PF00143.19 EST49595.1 - 0.021 15.0 5.1 0.026 14.7 5.1 1.1 1 0 0 1 1 1 0 Interferon alpha/beta domain OSCP PF00213.18 EST49595.1 - 0.029 14.5 3.4 0.037 14.1 3.4 1.1 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit Calici_coat_C PF08435.11 EST49595.1 - 0.041 13.4 0.4 0.053 13.0 0.4 1.1 1 0 0 1 1 1 0 Calicivirus coat protein C-terminal Fib_alpha PF08702.10 EST49595.1 - 0.34 11.1 8.8 0.49 10.6 8.8 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Sec62 PF03839.16 EST49600.1 - 7.2 6.0 5.4 11 5.5 5.4 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4748 PF15932.5 EST49603.1 - 0.18 11.6 1.1 0.34 10.7 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) DUF3042 PF11240.8 EST49603.1 - 1.5 8.9 4.3 3.4 7.8 4.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) Bacteriocin_IIc PF10439.9 EST49603.1 - 3.3 7.9 9.4 6 7.1 9.4 1.3 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DUF2613 PF11021.8 EST49604.1 - 0.042 14.0 0.7 0.12 12.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Histone PF00125.24 EST49605.1 - 8.5e-12 45.6 1.0 4e-11 43.4 0.1 1.9 1 1 1 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EST49605.1 - 2.8e-08 33.9 0.1 5e-08 33.1 0.0 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-18kDa PF02269.16 EST49605.1 - 0.025 14.6 0.9 0.038 14.0 0.9 1.5 1 1 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Histone_H2A_C PF16211.5 EST49605.1 - 0.19 11.5 0.0 0.19 11.5 0.0 2.4 3 0 0 3 3 3 0 C-terminus of histone H2A Protocadherin PF08374.11 EST49606.1 - 0.0068 16.4 0.4 0.013 15.5 0.4 1.3 1 0 0 1 1 1 1 Protocadherin EphA2_TM PF14575.6 EST49606.1 - 0.021 15.7 0.7 0.056 14.3 0.7 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 EST49606.1 - 0.12 12.3 0.5 0.2 11.5 0.5 1.3 1 0 0 1 1 1 0 TMEM154 protein family Fe_hyd_lg_C PF02906.14 EST49607.1 - 8.7e-66 222.0 2.2 1.4e-65 221.4 2.2 1.3 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fer4 PF00037.27 EST49607.1 - 3.6e-13 48.7 11.9 3.1e-08 33.1 1.9 2.8 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_9 PF13187.6 EST49607.1 - 8e-11 41.9 15.5 5.5e-09 36.1 4.2 3.9 3 2 1 4 4 4 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 EST49607.1 - 8.3e-11 42.3 7.5 8.3e-11 42.3 7.5 2.9 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 EST49607.1 - 4.1e-09 36.1 18.6 6.9e-05 22.7 2.6 3.6 3 0 0 3 3 3 3 4Fe-4S binding domain Fer4_10 PF13237.6 EST49607.1 - 1.4e-07 31.5 3.0 1.7e-05 24.8 0.4 3.7 4 1 0 4 4 3 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 EST49607.1 - 7.2e-06 26.8 11.1 7e-05 23.7 0.2 3.7 4 0 0 4 4 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 EST49607.1 - 7.9e-06 25.9 10.1 7.9e-06 25.9 10.1 3.4 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 EST49607.1 - 1.1e-05 25.3 26.7 0.00022 21.1 3.6 4.1 4 0 0 4 4 4 2 4Fe-4S binding domain Fer4_18 PF13746.6 EST49607.1 - 7.7e-05 22.9 4.7 0.025 14.8 0.2 3.7 4 0 0 4 4 4 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 EST49607.1 - 0.0001 22.8 7.7 0.0001 22.8 7.7 2.9 3 2 3 6 6 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.6 EST49607.1 - 0.00017 22.3 11.7 0.019 15.7 0.3 3.3 3 0 0 3 3 3 2 4Fe-4S single cluster domain Fer4_22 PF17179.4 EST49607.1 - 0.00024 21.9 11.6 0.016 16.0 0.5 4.0 4 0 0 4 4 4 2 4Fe-4S dicluster domain Fe_hyd_SSU PF02256.17 EST49607.1 - 0.00044 20.3 0.0 0.00091 19.3 0.0 1.5 1 0 0 1 1 1 1 Iron hydrogenase small subunit Fer4_8 PF13183.6 EST49607.1 - 0.00046 20.6 8.2 0.00046 20.6 8.2 2.9 3 1 1 4 4 3 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 EST49607.1 - 0.0025 18.3 7.3 0.24 12.0 1.0 2.9 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_4 PF12800.7 EST49607.1 - 0.0031 17.9 2.1 0.0031 17.9 2.1 4.1 4 0 0 4 4 3 1 4Fe-4S binding domain Fer4_3 PF12798.7 EST49607.1 - 0.054 14.4 7.6 0.054 14.4 7.6 4.4 4 0 0 4 4 4 0 4Fe-4S binding domain VIT PF08487.10 EST49608.1 - 0.019 15.2 0.1 0.32 11.2 0.0 2.0 2 0 0 2 2 2 0 Vault protein inter-alpha-trypsin domain EGF PF00008.27 EST49608.1 - 0.088 13.1 10.3 0.25 11.7 10.3 1.8 1 0 0 1 1 1 0 EGF-like domain EGF_2 PF07974.13 EST49608.1 - 0.32 11.4 10.7 0.35 11.3 8.7 2.3 1 1 0 1 1 1 0 EGF-like domain Arm PF00514.23 EST49609.1 - 6.4e-39 130.8 16.4 1.2e-08 34.7 0.0 9.3 9 0 0 9 9 9 7 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EST49609.1 - 1.2e-14 54.5 7.9 3.4e-06 27.4 1.1 5.1 3 2 2 5 5 5 5 HEAT repeats Adaptin_N PF01602.20 EST49609.1 - 4.6e-10 38.7 6.6 2.1e-05 23.3 2.0 3.2 2 1 1 3 3 3 2 Adaptin N terminal region HEAT PF02985.22 EST49609.1 - 2.5e-09 36.6 10.8 0.037 14.3 0.2 7.2 8 0 0 8 8 8 2 HEAT repeat Cnd1 PF12717.7 EST49609.1 - 1.3e-08 35.1 0.3 0.29 11.1 0.2 3.9 2 2 2 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EST49609.1 - 6.4e-06 26.5 18.8 0.57 10.7 0.2 6.5 6 2 3 9 9 9 4 HEAT-like repeat RICTOR_V PF14668.6 EST49609.1 - 0.00033 20.8 0.2 0.082 13.2 0.0 3.7 3 1 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 Arm_2 PF04826.13 EST49609.1 - 0.0007 19.1 0.4 0.55 9.6 0.0 3.4 3 0 0 3 3 3 1 Armadillo-like V-ATPase_H_C PF11698.8 EST49609.1 - 0.001 19.2 0.3 1.2 9.2 0.0 4.1 4 1 1 5 5 5 1 V-ATPase subunit H Proteasom_PSMB PF10508.9 EST49609.1 - 0.0029 16.2 2.4 0.85 8.0 0.1 2.3 1 1 0 2 2 2 2 Proteasome non-ATPase 26S subunit HEAT_PBS PF03130.16 EST49609.1 - 0.0077 16.8 4.1 5.3 8.0 0.0 5.3 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Mo25 PF08569.11 EST49609.1 - 0.0086 15.5 0.2 0.92 8.8 0.1 3.0 2 1 0 2 2 2 1 Mo25-like M11L PF11099.8 EST49609.1 - 0.01 16.1 0.6 6.9 6.9 0.1 3.5 2 1 1 3 3 3 0 Apoptosis regulator M11L like ALF PF03752.13 EST49609.1 - 0.94 9.5 3.7 21 5.2 1.3 3.3 3 0 0 3 3 3 0 Short repeats of unknown function MFS_1 PF07690.16 EST49611.1 - 0.12 11.3 38.9 0.028 13.3 35.5 1.6 1 1 1 2 2 2 0 Major Facilitator Superfamily DUF2613 PF11021.8 EST49612.1 - 0.033 14.3 0.0 0.12 12.4 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) DUF4748 PF15932.5 EST49613.1 - 0.17 11.6 1.1 0.34 10.7 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) DUF3042 PF11240.8 EST49613.1 - 2.5 8.2 5.2 5.6 7.1 5.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) UQ_con PF00179.26 EST49615.1 - 5.3e-21 74.7 0.0 6.1e-21 74.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme GP57 PF17594.2 EST49616.1 - 0.16 11.7 3.0 0.11 12.2 0.9 1.8 2 0 0 2 2 2 0 Phage Tail fiber assembly helper gene product 57 FlaC_arch PF05377.11 EST49616.1 - 0.33 11.4 2.1 3.4 8.1 0.2 3.0 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) Atg14 PF10186.9 EST49616.1 - 0.39 9.8 13.9 0.46 9.5 13.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PAXX PF15384.6 EST49617.1 - 0.0066 16.2 0.3 0.0092 15.7 0.3 1.3 1 0 0 1 1 1 1 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 Lzipper-MIP1 PF14389.6 EST49617.1 - 0.072 13.4 0.6 0.17 12.2 0.2 1.9 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 BRX_N PF13713.6 EST49617.1 - 0.082 12.7 0.2 0.18 11.6 0.0 1.8 2 0 0 2 2 2 0 Transcription factor BRX N-terminal domain SlyX PF04102.12 EST49617.1 - 0.9 10.2 4.5 20 5.9 0.3 2.6 2 1 1 3 3 3 0 SlyX zf-C2H2 PF00096.26 EST49618.1 - 4.5e-21 74.1 32.8 2.4e-05 24.6 0.2 5.3 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EST49618.1 - 9e-21 72.8 29.9 0.00042 20.9 0.1 5.3 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EST49618.1 - 1.1e-09 38.2 26.8 0.0099 16.3 0.2 6.3 6 0 0 6 6 6 3 Zinc-finger double domain zf-met PF12874.7 EST49618.1 - 5e-09 36.2 22.4 0.14 12.6 0.8 5.5 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EST49618.1 - 1.8e-08 34.5 27.1 0.011 16.0 0.9 5.8 6 0 0 6 6 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EST49618.1 - 7.2e-06 26.3 26.6 0.075 13.4 1.8 5.0 1 1 4 5 5 5 3 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 EST49618.1 - 3.3e-05 23.7 34.1 0.14 12.2 1.8 5.9 5 1 0 5 5 5 3 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 EST49618.1 - 3.6e-05 23.8 23.2 0.14 12.3 5.9 5.0 2 1 3 5 5 5 4 Zinc ribbon domain Elf1 PF05129.13 EST49618.1 - 4.5e-05 23.4 2.0 4.5e-05 23.4 2.0 3.8 2 2 1 3 3 3 2 Transcription elongation factor Elf1 like zf-C2H2_11 PF16622.5 EST49618.1 - 7.9e-05 22.3 21.4 0.063 13.0 0.9 4.6 5 0 0 5 5 4 3 zinc-finger C2H2-type zf_UBZ PF18439.1 EST49618.1 - 0.00016 21.2 17.7 0.9 9.2 0.1 5.4 5 0 0 5 5 5 3 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 EST49618.1 - 0.00041 20.6 2.1 0.00041 20.6 2.1 3.4 2 2 2 4 4 4 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 EST49618.1 - 0.00044 20.5 2.6 0.00044 20.5 2.6 2.8 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-C2H2_9 PF16293.5 EST49618.1 - 0.00065 19.5 9.8 5.9 6.8 0.0 4.9 3 2 2 5 5 5 0 C2H2 type zinc-finger (1 copy) BolA PF01722.18 EST49618.1 - 0.0023 18.2 2.8 0.81 10.0 0.0 3.4 2 1 1 3 3 3 1 BolA-like protein HypA PF01155.19 EST49618.1 - 0.0024 17.9 17.8 0.2 11.7 1.5 4.1 1 1 3 4 4 4 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-FCS PF06467.14 EST49618.1 - 0.0025 17.7 17.5 0.84 9.6 4.5 4.6 4 1 0 4 4 4 1 MYM-type Zinc finger with FCS sequence motif zf-C2H2_3rep PF18868.1 EST49618.1 - 0.0027 18.4 17.1 0.025 15.2 12.0 3.2 1 1 1 2 2 2 1 Zinc finger C2H2-type, 3 repeats DUF2340 PF10209.9 EST49618.1 - 0.0049 17.3 0.8 0.014 15.9 0.3 1.8 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2340) ADK_lid PF05191.14 EST49618.1 - 0.0063 16.5 7.6 1.2 9.2 0.1 3.7 3 1 1 4 4 4 1 Adenylate kinase, active site lid LIM PF00412.22 EST49618.1 - 0.0079 16.4 22.6 1.4 9.2 2.0 4.8 2 2 2 4 4 4 1 LIM domain HNH PF01844.23 EST49618.1 - 0.01 16.0 22.1 5.3 7.3 0.4 5.1 5 0 0 5 5 5 0 HNH endonuclease DZR PF12773.7 EST49618.1 - 0.011 15.8 16.1 7.1e+02 0.3 14.9 3.1 1 1 0 1 1 1 0 Double zinc ribbon GAGA PF09237.11 EST49618.1 - 0.011 15.5 2.2 0.82 9.5 0.3 2.6 1 1 1 2 2 2 0 GAGA factor zinc_ribbon_15 PF17032.5 EST49618.1 - 0.013 16.2 16.8 0.42 11.4 4.6 3.0 1 1 0 2 2 2 0 zinc-ribbon family HNH_5 PF14279.6 EST49618.1 - 0.021 14.7 17.4 0.25 11.2 3.6 4.2 4 0 0 4 4 4 0 HNH endonuclease zf_C2H2_ZHX PF18387.1 EST49618.1 - 0.035 13.8 2.2 0.035 13.8 2.2 4.7 4 1 1 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF3268 PF11672.8 EST49618.1 - 0.049 14.0 9.0 0.71 10.2 1.2 3.1 3 0 0 3 3 3 0 zinc-finger-containing domain zf-RRN7 PF11781.8 EST49618.1 - 0.053 13.2 13.8 2 8.2 0.2 5.0 5 0 0 5 5 5 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zinc_ribbon_4 PF13717.6 EST49618.1 - 0.073 13.0 17.3 8.7 6.4 0.1 5.1 4 1 0 4 4 4 0 zinc-ribbon domain Prok-RING_1 PF14446.6 EST49618.1 - 0.083 12.8 20.8 1.3 9.0 3.3 5.0 3 2 0 3 3 3 0 Prokaryotic RING finger family 1 Ta0938 PF11494.8 EST49618.1 - 0.094 13.0 0.1 0.094 13.0 0.1 3.2 1 1 2 3 3 3 0 Ta0938 STPPase_N PF16891.5 EST49618.1 - 0.14 12.6 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain DUF4524 PF15025.6 EST49618.1 - 0.21 11.3 3.8 0.25 11.1 1.5 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4524) zf_C2H2_10 PF18414.1 EST49618.1 - 0.26 10.9 5.4 3.5 7.3 0.0 3.8 3 0 0 3 3 3 0 C2H2 type zinc-finger YhfH PF14149.6 EST49618.1 - 0.26 11.3 13.4 16 5.6 0.3 4.5 4 0 0 4 4 4 0 YhfH-like protein zf-C2HC_2 PF13913.6 EST49618.1 - 0.26 11.2 0.2 0.26 11.2 0.2 5.1 5 1 0 5 5 5 0 zinc-finger of a C2HC-type zinc-ribbons_6 PF07191.12 EST49618.1 - 0.44 10.6 20.2 3.5 7.7 4.9 4.3 1 1 2 3 3 3 0 zinc-ribbons zinc_ribbon_9 PF14369.6 EST49618.1 - 0.47 10.7 0.1 0.47 10.7 0.1 4.7 6 0 0 6 6 5 0 zinc-ribbon zinc_ribbon_5 PF13719.6 EST49618.1 - 0.85 9.4 0.0 0.85 9.4 0.0 4.7 5 0 0 5 5 4 0 zinc-ribbon domain RNA_POL_M_15KD PF02150.16 EST49618.1 - 0.86 9.5 15.2 5.9 6.9 0.1 4.6 5 0 0 5 5 5 0 RNA polymerases M/15 Kd subunit Zn-C2H2_12 PF18112.1 EST49618.1 - 0.88 10.1 16.0 5.9 7.4 0.8 5.1 5 0 0 5 5 5 0 Autophagy receptor zinc finger-C2H2 domain zf-BED PF02892.15 EST49618.1 - 1 9.5 23.2 2.3 8.3 0.7 5.2 2 2 3 5 5 5 0 BED zinc finger DUF983 PF06170.12 EST49618.1 - 2.2 8.7 15.5 9.6 6.7 0.1 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF983) Terminase_GpA PF05876.12 EST49618.1 - 2.5 6.5 11.1 0.13 10.8 1.1 2.3 1 1 0 2 2 2 0 Phage terminase large subunit (GpA) TF_Zn_Ribbon PF08271.12 EST49618.1 - 4.9 6.8 20.7 2.2 7.8 3.0 4.5 3 2 0 3 3 3 0 TFIIB zinc-binding DUF2225 PF09986.9 EST49618.1 - 8.4 6.0 16.1 1.6 8.4 0.2 4.1 2 2 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) OrfB_Zn_ribbon PF07282.11 EST49618.1 - 9.9 6.2 21.0 4.1 7.4 3.2 4.6 1 1 4 5 5 5 0 Putative transposase DNA-binding domain TPR_1 PF00515.28 EST49619.1 - 5.1e-08 32.4 6.0 0.00066 19.4 0.1 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EST49619.1 - 5.9e-08 32.2 2.9 0.024 14.7 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EST49619.1 - 4.6e-05 23.0 2.4 0.27 10.9 0.3 3.4 2 2 0 2 2 2 2 TPR repeat TPR_17 PF13431.6 EST49619.1 - 0.00054 20.2 1.4 0.33 11.4 0.2 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EST49619.1 - 0.011 16.0 0.1 0.22 11.9 0.0 2.8 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 EST49619.1 - 0.015 15.6 0.1 0.035 14.4 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Type_III_YscG PF09477.10 EST49619.1 - 0.018 15.1 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_8 PF13181.6 EST49619.1 - 0.04 14.2 4.0 1.3 9.4 0.0 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EST49619.1 - 0.075 13.1 0.4 3.6 7.8 0.0 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EST49619.1 - 0.11 13.2 2.3 1.8 9.4 0.0 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 EST49619.1 - 0.24 11.9 1.5 0.38 11.3 0.6 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-C2H2 PF00096.26 EST49621.1 - 4.5e-21 74.1 32.8 2.4e-05 24.6 0.2 5.3 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EST49621.1 - 9e-21 72.8 29.9 0.00042 20.9 0.1 5.3 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EST49621.1 - 1.1e-09 38.2 26.8 0.0099 16.3 0.2 6.3 6 0 0 6 6 6 3 Zinc-finger double domain zf-met PF12874.7 EST49621.1 - 5e-09 36.2 22.4 0.14 12.6 0.8 5.5 5 0 0 5 5 5 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EST49621.1 - 1.8e-08 34.5 27.1 0.011 16.0 0.9 5.8 6 0 0 6 6 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EST49621.1 - 7.2e-06 26.3 26.6 0.075 13.4 1.8 5.0 1 1 4 5 5 5 3 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 EST49621.1 - 3.3e-05 23.7 34.1 0.14 12.2 1.8 5.9 5 1 0 5 5 5 3 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 EST49621.1 - 3.6e-05 23.8 23.2 0.14 12.3 5.9 5.0 2 1 3 5 5 5 4 Zinc ribbon domain Elf1 PF05129.13 EST49621.1 - 4.5e-05 23.4 2.0 4.5e-05 23.4 2.0 3.8 2 2 1 3 3 3 2 Transcription elongation factor Elf1 like zf-C2H2_11 PF16622.5 EST49621.1 - 7.9e-05 22.3 21.4 0.063 13.0 0.9 4.6 5 0 0 5 5 4 3 zinc-finger C2H2-type zf_UBZ PF18439.1 EST49621.1 - 0.00016 21.2 17.7 0.9 9.2 0.1 5.4 5 0 0 5 5 5 3 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 EST49621.1 - 0.00041 20.6 2.1 0.00041 20.6 2.1 3.4 2 2 2 4 4 4 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 EST49621.1 - 0.00044 20.5 2.6 0.00044 20.5 2.6 2.8 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-C2H2_9 PF16293.5 EST49621.1 - 0.00065 19.5 9.8 5.9 6.8 0.0 4.9 3 2 2 5 5 5 0 C2H2 type zinc-finger (1 copy) BolA PF01722.18 EST49621.1 - 0.0023 18.2 2.8 0.81 10.0 0.0 3.4 2 1 1 3 3 3 1 BolA-like protein HypA PF01155.19 EST49621.1 - 0.0024 17.9 17.8 0.2 11.7 1.5 4.1 1 1 3 4 4 4 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-FCS PF06467.14 EST49621.1 - 0.0025 17.7 17.5 0.84 9.6 4.5 4.6 4 1 0 4 4 4 1 MYM-type Zinc finger with FCS sequence motif zf-C2H2_3rep PF18868.1 EST49621.1 - 0.0027 18.4 17.1 0.025 15.2 12.0 3.2 1 1 1 2 2 2 1 Zinc finger C2H2-type, 3 repeats DUF2340 PF10209.9 EST49621.1 - 0.0049 17.3 0.8 0.014 15.9 0.3 1.8 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2340) ADK_lid PF05191.14 EST49621.1 - 0.0063 16.5 7.6 1.2 9.2 0.1 3.7 3 1 1 4 4 4 1 Adenylate kinase, active site lid LIM PF00412.22 EST49621.1 - 0.0079 16.4 22.6 1.4 9.2 2.0 4.8 2 2 2 4 4 4 1 LIM domain HNH PF01844.23 EST49621.1 - 0.01 16.0 22.1 5.3 7.3 0.4 5.1 5 0 0 5 5 5 0 HNH endonuclease DZR PF12773.7 EST49621.1 - 0.011 15.8 16.1 7.1e+02 0.3 14.9 3.1 1 1 0 1 1 1 0 Double zinc ribbon GAGA PF09237.11 EST49621.1 - 0.011 15.5 2.2 0.82 9.5 0.3 2.6 1 1 1 2 2 2 0 GAGA factor zinc_ribbon_15 PF17032.5 EST49621.1 - 0.013 16.2 16.8 0.42 11.4 4.6 3.0 1 1 0 2 2 2 0 zinc-ribbon family HNH_5 PF14279.6 EST49621.1 - 0.021 14.7 17.4 0.25 11.2 3.6 4.2 4 0 0 4 4 4 0 HNH endonuclease zf_C2H2_ZHX PF18387.1 EST49621.1 - 0.035 13.8 2.2 0.035 13.8 2.2 4.7 4 1 1 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF3268 PF11672.8 EST49621.1 - 0.049 14.0 9.0 0.71 10.2 1.2 3.1 3 0 0 3 3 3 0 zinc-finger-containing domain zf-RRN7 PF11781.8 EST49621.1 - 0.053 13.2 13.8 2 8.2 0.2 5.0 5 0 0 5 5 5 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zinc_ribbon_4 PF13717.6 EST49621.1 - 0.073 13.0 17.3 8.7 6.4 0.1 5.1 4 1 0 4 4 4 0 zinc-ribbon domain Prok-RING_1 PF14446.6 EST49621.1 - 0.083 12.8 20.8 1.3 9.0 3.3 5.0 3 2 0 3 3 3 0 Prokaryotic RING finger family 1 Ta0938 PF11494.8 EST49621.1 - 0.094 13.0 0.1 0.094 13.0 0.1 3.2 1 1 2 3 3 3 0 Ta0938 STPPase_N PF16891.5 EST49621.1 - 0.14 12.6 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain DUF4524 PF15025.6 EST49621.1 - 0.21 11.3 3.8 0.25 11.1 1.5 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4524) zf_C2H2_10 PF18414.1 EST49621.1 - 0.26 10.9 5.4 3.5 7.3 0.0 3.8 3 0 0 3 3 3 0 C2H2 type zinc-finger YhfH PF14149.6 EST49621.1 - 0.26 11.3 13.4 16 5.6 0.3 4.5 4 0 0 4 4 4 0 YhfH-like protein zf-C2HC_2 PF13913.6 EST49621.1 - 0.26 11.2 0.2 0.26 11.2 0.2 5.1 5 1 0 5 5 5 0 zinc-finger of a C2HC-type zinc-ribbons_6 PF07191.12 EST49621.1 - 0.44 10.6 20.2 3.5 7.7 4.9 4.3 1 1 2 3 3 3 0 zinc-ribbons zinc_ribbon_9 PF14369.6 EST49621.1 - 0.47 10.7 0.1 0.47 10.7 0.1 4.7 6 0 0 6 6 5 0 zinc-ribbon zinc_ribbon_5 PF13719.6 EST49621.1 - 0.85 9.4 0.0 0.85 9.4 0.0 4.7 5 0 0 5 5 4 0 zinc-ribbon domain RNA_POL_M_15KD PF02150.16 EST49621.1 - 0.86 9.5 15.2 5.9 6.9 0.1 4.6 5 0 0 5 5 5 0 RNA polymerases M/15 Kd subunit Zn-C2H2_12 PF18112.1 EST49621.1 - 0.88 10.1 16.0 5.9 7.4 0.8 5.1 5 0 0 5 5 5 0 Autophagy receptor zinc finger-C2H2 domain zf-BED PF02892.15 EST49621.1 - 1 9.5 23.2 2.3 8.3 0.7 5.2 2 2 3 5 5 5 0 BED zinc finger DUF983 PF06170.12 EST49621.1 - 2.2 8.7 15.5 9.6 6.7 0.1 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF983) Terminase_GpA PF05876.12 EST49621.1 - 2.5 6.5 11.1 0.13 10.8 1.1 2.3 1 1 0 2 2 2 0 Phage terminase large subunit (GpA) TF_Zn_Ribbon PF08271.12 EST49621.1 - 4.9 6.8 20.7 2.2 7.8 3.0 4.5 3 2 0 3 3 3 0 TFIIB zinc-binding DUF2225 PF09986.9 EST49621.1 - 8.4 6.0 16.1 1.6 8.4 0.2 4.1 2 2 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) OrfB_Zn_ribbon PF07282.11 EST49621.1 - 9.9 6.2 21.0 4.1 7.4 3.2 4.6 1 1 4 5 5 5 0 Putative transposase DNA-binding domain Type_III_YscG PF09477.10 EST49622.1 - 0.0054 16.8 0.0 0.0082 16.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_2 PF07719.17 EST49622.1 - 0.0063 16.5 1.4 2.3 8.6 0.0 3.2 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 EST49622.1 - 0.0066 16.8 0.2 0.0097 16.2 0.2 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 EST49622.1 - 0.015 15.7 0.4 0.084 13.3 0.1 2.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EST49622.1 - 0.015 15.1 0.4 0.41 10.6 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 EST49622.1 - 0.035 13.8 0.2 0.2 11.4 0.0 2.2 1 1 0 2 2 2 0 TPR repeat TPR_19 PF14559.6 EST49622.1 - 0.065 13.7 0.9 0.12 12.9 0.9 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Diplomonada/Spironucleus_salmonicida-SSK3.0/GCA_000497125.1_SSK3.0_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Diplomonada/Spironucleus_salmonicida-SSK3.0/GCA_000497125.1_SSK3.0_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Diplomonada/Spironucleus_salmonicida-SSK3.0/GCA_000497125.1_SSK3.0_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Diplomonada/Spironucleus_salmonicida-SSK3.0/GCA_000497125.1_SSK3.0_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 09:57:28 2019 # [ok]